90 results match your criteria Chorea Gravidarum

Chorea gravidarum associated with systemic lupus erythematosus and antiphospholipid syndrome: case report.

Cir Cir 2020 ;88(Suppl 1):59-62

Servicio de Reumatología, Hospital Juárez de México, Ciudad de México, México.

Las manifestaciones neuropsiquiátricas en los pacientes con lupus eritematoso sistémico (LES) y síndrome antifosfolípido (SAF) secundario son muy frecuentes. En ambos casos, la fisiopatología se correlaciona con vasculopatía asociada a anticuerpos antifosfolípido y neurotoxicidad por anticuerpos y citocinas. La corea es el único trastorno del movimiento incluido en los 19 síndromes neuropsiquiátricos del LES según el American College of Rheumatology, con presentación inusual (prevalencia del 2%), y puede ocurrir como primera manifestación de la enfermedad. Read More

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September 2021

Treatment of Secondary Chorea: A Review of the Current Literature.

Tremor Other Hyperkinet Mov (N Y) 2020 07 16;10:22. Epub 2020 Jul 16.

Icahn School of Medicine at Mount Sinai, US.

Background: Chorea consists of involuntary movements affecting the limbs, trunk, neck or face, that can move from one body part to another. Chorea is conceptualized as being "primary" when it is attributed to Huntington's disease (HD) or other genetic etiologies, or "secondary" when it is related to infectious, pharmacologic, metabolic, autoimmune disorders, or paraneoplastic syndromes. The mainstay of the secondary chorea management is treating the underlying causative disorder; here we review the literature regarding secondary chorea. Read More

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Movement disorders in pregnancy.

Handb Clin Neurol 2020 ;172:219-239

Division of Neurology, Department of Medicine, University of Alberta, Edmonton, AB, Canada. Electronic address:

Movement disorders in women during pregnancy are uncommon. Therefore, high quality studies are limited, and guidelines are lacking for the treatment of movement disorders in pregnancy, thus posing a significant therapeutic challenge for the treating physicians. In this chapter, we discuss movement disorders that arise during pregnancy and the preexisting movement disorders during pregnancy. Read More

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Rev Colomb Obstet Ginecol 2019 09;70(3):189-194

Docente del Departamento de Ginecobstetricia, Universidad Industrial de Santander, Unidad de Medicina Materno-Fetal del Hospital Universitario de Santander, Bucaramanga (Colombia).

Objective: To present a case of chorea gravidarum and conduct a review of the published literature on the treatment for this condition, and on maternal and fetal prognosis.

Methods: Case presentation of a 16-year-old primiparous patient admitted to a Level III public hospital at 8 weeks of gestation complaining of involuntary head and limb movements and right lower limb hyperreflexia lasting three days. The patient had a history of Sydenham chorea. Read More

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September 2019

Identifying the aetiology of sudden acute abnormal involuntary movements in a primigravid.

BMJ Case Rep 2018 Dec 19;11(1). Epub 2018 Dec 19.

Department of Obstetrics and Gynecology, Philippine General Hospital, Manila, Metro Manila, Philippines.

A 20-year-old primigravid experienced sudden stiffening of the neck, upper and lower extremities and trunk associated with joint pains. She was generally well before hospital admission with no history of attacks, except for her inflammatory bowel disease that was treated more than a year ago. During physical examination, the patient manifested neck flexion deviated to the right, deviation of the eyes downward and to the right, spooning of the upper extremities, exhibition of milkmaid's grip, extension of both lower extremities and jerky speech. Read More

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December 2018

Movement Disorders in Women.

Semin Neurol 2017 12 21;37(6):653-660. Epub 2017 Dec 21.

Division of Movement Disorders, Department of Neurology, Massachusetts General Hospital, Boston, Massachusetts.

Movement disorders such as Parkinson's disease (PD), restless legs syndrome (RLS), chorea, essential tremor, and Tourette syndrome, occur in men and women of all ages. Yet, considerable sex differences in epidemiology, clinical features, and treatment exist in these disorders. In this review, we highlight key differences in the evaluation and management of women with movement disorders, addressing sex-specific complications of treatment and unique challenges surrounding the management of movement disorders during pregnancy. Read More

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December 2017

Chorea gravidarum associated with Moyamoya angiopathy treated with alpha-methyldopa.

Clin Neurol Neurosurg 2017 07 6;158:126. Epub 2017 May 6.

Department of Neurology, Alfried-Krupp-Hospital, Essen, Germany. Electronic address:

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Sanjay Pandey

J Assoc Physicians India 2013 Jul;61(7):471-4, 483

Chorea is an involuntary movement disorder characterised by flowing and rhythmic in nature. Hyperkinetic movement disorders such as myoclonus may be mistaken for chorea. Pathogenes of chorea is complex and results from dysfunction of network between motor nucleus of thalamus and subcortical nuclei including globus pallidus interna. Read More

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Sex differences in Parkinson's disease and other movement disorders.

Exp Neurol 2014 Sep 28;259:44-56. Epub 2014 Mar 28.

Parkinson's Disease and Movement Disorders Center, 330 S. 9th St, 2nd Floor, Philadelphia, PA 19107, USA.

Movement disorders including Parkinson's disease (PD), Huntington's disease (HD), chorea, tics, and Tourette's syndrome (TS) display sex differences in disease susceptibility, disease pathogenesis, and clinical presentation. PD is more common in males than in females. Epidemiologic studies suggest that exposure to endogenous and exogenous estrogen contributes to these sex differences. Read More

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September 2014

Movement disorders in pregnancy.

Continuum (Minneap Minn) 2014 Feb;20(1 Neurology of Pregnancy):148-61

Purpose Of Review: This review discusses movement disorders that occur during pregnancy, the treatment of preexisting movement disorders, and the influence the pregnant state has on movement disorders symptoms, in order to guide clinicians in providing better counseling for female patients who are pregnant or considering pregnancy.

Recent Findings: Unique considerations for movement disorders during pregnancy include investigations and their safety during pregnancy and the impact of treatment on both the pregnant patient and her fetus.

Summary: The most common movement disorders arising in pregnancy are restless leg syndrome and chorea gravidarum. Read More

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February 2014

[Antiphospolipid syndrome related chorea gravidarum case with psychotic symptoms misdiagnosed as conversion disorder: case report].

Turk Psikiyatri Derg 2013 ;24(4):280-3

Chorea gravidarum (CG) is a rare movement disorder characterized by rapid, irregular randomly distributed involuntary movements during pregnancy. Similar to Sydenham chorea, psychiatric symptoms may be observed in cases of CG. CG may be idiopathic or secondary to an underlying cause. Read More

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Chorea gravidarum: a rarity in West still haunts pregnant women in the East.

BMJ Case Rep 2013 Jun 27;2013. Epub 2013 Jun 27.

Department of Internal Medicine, VCSG Government Medical Sciences and Research Institute, Srinagar (Garhwal), Uttarakhand, India.

A pregnant woman, in her early 20s, presents with chorea following an emotional outburst. While the family members feel it to be a spirit haunting her, we try to establish the medical diagnosis of the present condition. There is a history of rheumatic fever in the past and examination reveals choreioathetoid jerky movements of her upper limbs with jerky speech, spooning of her limbs and demonstration of milkmaid's grip. Read More

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Demonstration of choreic movements in a case of chorea gravidarum.

BMJ Case Rep 2013 Feb 15;2013. Epub 2013 Feb 15.

Department of Internal Medicine, VCSG Government Medical Sciences and Research Institute, Srinagar (Garhwal), Uttarakhand, India.

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February 2013

[Anaestheia for valve replacement in the second trimester of pregnancy].

Rev Esp Anestesiol Reanim 2014 Jan 8;61(1):35-8. Epub 2012 Dec 8.

Servicio de Anestesiología, Hospital de Clínicas, Facultad de Medicina, Universidad de la República, Montevideo, Uruguay.

Cardiac surgery in the pregnant woman gives rise to several anesthetic challenges, as the mother, but mainly the fetus, have a risk of high morbidity and mortality. In this context, the cardiopulmonary bypass is the most complex period, owing to the risks of fetal hypoxia it entails. Due to the absence, for ethical reasons, of prospective trials that provide generally accepted guidelines in intraoperative management, it means that physicians have to work based on case reports in the literature. Read More

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January 2014

Gowers' Queen Square case notes on chorea: a 21st century re-appraisal.

Eur Neurol 2013 3;69(1):48-52. Epub 2012 Nov 3.

Neurology Division, University Hospital, Belo Horizonte, Brazil.

Objective: To analyze the case notes of 127 patients with chorea admitted to the National Hospital at Queen Square, London, under the care of William Richard Gowers and review his contribution to the study of choreas.

Methods: We consulted the case books available at the Queen Square Library, from 1878 to 1911, comprising 42 volumes.

Results: 97 patients (76. Read More

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Pregnancy in patients with Sydenham's Chorea.

Parkinsonism Relat Disord 2012 Jun 10;18(5):458-61. Epub 2012 Jan 10.

Movement Disorders Unit - Neurology Service, Department of Internal Medicine, The Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

Background: Sydenham's Chorea is a frequent cause of chorea during pregnancy, chorea gravidarum. The aim of this article is to describe the effect of pregnancy in a consecutive series of patients with diagnosis of Sydenham's Chorea.

Methods: A chart review was performed of all patients with the diagnosis of Sydenham's Chorea followed up at our institution from 07/1993 through 08/2010 and who became pregnant. Read More

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Chorea gravidarum.

Handb Clin Neurol 2011 ;100:231-5

Department of Neurology, University of Maryland School of Medicine, Baltimore, MD 21201, USA.

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Movement disorders and pregnancy: a review of the literature.

Mov Disord 2010 Apr;25(6):665-71

Department of Neurology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.

Pregnant patients are rarely encountered in the movement disorders clinic, but they present significant dilemmas regarding treatment and counseling for neurologists. While movement disorders in pregnancy once described those disorders arising de novo during pregnancy, such as chorea gravidarum or restless leg syndrome, advancing maternal age in Western countries will likely increase the number of women in whom pregnancy complicates a pre-existing movement disorder. Physicians treating these women must be aware of the impact of the movement disorder and its treatment on fertility, pregnancy, fetal development, lactation, and infant care. Read More

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[Chorea gravidarum. A case report].

Ginecol Obstet Mex 2009 Mar;77(3):156-9

Departamento de Ginecología y Obstetricia, Hospital General Salvador Zubirán Anchondo, Chihuahua, Chihuahua.

Chorea gravidarum is an uncommon condition characterized by involuntary movements, speaking alterations and in the affective status during first trimester pregnancy, the incidence is 1 by each 2275 pregnancies, it is self limiting and resolves when the pregnancy ends, most of the cases are idiopathic and the rest is associated to the antiphospholipid syndrome, rheumatic fever, thyrotoxicosis, systemic lupus erythematosus, syphilis, Huntington disease or induced by drugs. The recurrences can occur in the subsequent pregnancies. The dopamine antagonists as the haloperidol and the chlorpromazine are useful to control the symptoms and are safe at lower doses. Read More

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Consecutive pregnancy with chorea gravidarum associated with moyamoya disease.

J Perinatol 2009 Apr;29(4):317-9

Fertility Center of CHA General Hospital, Department of Obstetrics and Gynecology, College of Medicine, Pochon CHA University, Seoul, Korea.

Chorea gravidarum is uncommon movement disorder of pregnancy, characterized by involuntary, abrupt, non-rhythmic movements. It can be idiopathic or secondary to the underlying pathology. A 28-year-old, primigravida woman who was 8 weeks and 6 days of gestation presented with a history of involuntary choreiform movements in the left side limbs and facial twitch for 2 weeks. Read More

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The differential diagnosis of chorea.

Pract Neurol 2007 Nov;7(6):360-73

Department of Neurodegenerative Disease, UCL Institute of Neurology, London/National Hospital for Neurology and Neurosurgery, Queen Square, London, UK.

Chorea is a hyperkinetic movement disorder characterised by excessive spontaneous movements that are irregularly timed, randomly distributed and abrupt. In this article, the authors discuss the causes of chorea, particularly Huntington's disease and the genetic syndromes that may resemble it, including HDL1-3, inherited prion disease, spinocerebellar ataxias 1, 3 and 17, neuroacanthocytosis, dentatorubro-pallidoluysian atrophy (DRPLA), brain iron accumulation disorders, Wilson's disease, benign hereditary chorea, Friedreich's ataxia and mitochondrial disease. Acquired causes of chorea include vascular disease, post-infective autoimmune central nervous system disorders (PANDAS), drugs, systemic lupus erythematosus, antiphospholipid syndrome, thyrotoxicosis, AIDS, chorea gravidarum, and polycythaemia rubra vera. Read More

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November 2007

Movement disorders in pregnancy.

Semin Neurol 2007 Nov;27(5):467-75

Department of Neurology, David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Movement disorders are not commonly seen during pregnancy. As a result, there are few studies on whether disease manifestations are affected by the hormonal changes that occur during pregnancy or on the teratogenicity of commonly used medications for movement disorders on the developing fetus. This article discusses movement disorders that are seen only during pregnancy (chorea gravidarum) or that may present during pregnancy (restless legs syndrome), the effect that pregnancy has on symptoms and treatment (in Parkinson's disease, essential tremor, dystonia, tic disorders, and Wilson's disease), and the role of genetic testing for movement disorders in genetic counseling for pregnant women. Read More

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November 2007

Chorea gravidarum.

L M Palanivelu

J Obstet Gynaecol 2007 Apr;27(3):310

Department of Family Planning and Sexual Health, Luton Primary Care Trust, London, UK.

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The reduced expression of the HADH2 protein causes X-linked mental retardation, choreoathetosis, and abnormal behavior.

Am J Hum Genet 2007 Feb 28;80(2):372-7. Epub 2006 Dec 28.

Department of Obstetrics and Gynecology, Technical University, Munich, Germany.

Recently, we defined a new syndromic form of X-linked mental retardation in a 4-generation family with a unique clinical phenotype characterized by mild mental retardation, choreoathetosis, and abnormal behavior (MRXS10). Linkage analysis in this family revealed a candidate region of 13.4 Mb between markers DXS1201 and DXS991 on Xp11; therefore, mutation analysis was performed by direct sequencing in most of the 135 annotated genes located in the region. Read More

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February 2007

Psychosis complicating Chorea gravidarum.

I Brockington

Arch Womens Ment Health 2006 Mar 22;9(2):113-4. Epub 2006 Jan 22.

Lower Brockington Farm, Bredenbury, Bromyard, UK.

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Dystonia gravidarum: a new entity?

Mov Disord 2006 Jan;21(1):69-70

Division of Neurology, National University Hospital, Singapore.

We describe cervical dystonia occurring in a 31-year-old, previously well, primigravid, primiparous Chinese woman at 4 weeks' amenorrhea, which was ameliorated with low-dose clonazepam and disappeared completely by the end of the second trimester without recurring despite her being tapered off benzodiazepine therapy. Investigations were unremarkable for structural and biochemical causes of dystonia. Chorea, paraballismus, and restless legs syndrome are known to occur during pregnancy, attributable to high estrogen levels. Read More

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January 2006

[Sydenham's chorea. A clinical analysis of 55 patients with a prolonged follow-up].

Rev Neurol 2004 Nov 1-15;39(9):810-5

Servicio de Neurología, Hospital Barros Luco-Trudeau, Santiago de Chile, Chile.

Introduction: Sydenham's chorea is permanently on the rise in developing countries and may suddenly reappear in developed nations.

Patients And Methods: We studied a prospective series of 55 cases, involving a total of 89 outbreaks with long-term follow-ups. All the cases were considered to be rheumatic from the outset, whether they were pure choreas or accompanied by the other signs from the Jones criterion, 38 and 17 respectively, in the first outbreak. Read More

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Chorea in a pregnant woman with rheumatic mitral stenosis.

Can J Cardiol 2003 May;19(6):719-21

Divison of Cardiology, St Michael's Hospital, Toronto, Canada.

Chorea gravidarum is a rare movement disorder of pregnancy with a broad differential diagnosis. Although often a benign condition, it may indicate underlying acute rheumatic fever, antiphospholipid antibody syndrome or a hypercoagulable state. However, now that rheumatic fever is rare in western countries, chorea gravidarum occurs most commonly in patients with chronic rheumatic heart disease. Read More

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Chorea gravidarum: a case report.

J Matern Fetal Neonatal Med 2002 Nov;12(5):353-4

Kartal Research Hospital, Department of Obstetrics and Gynecology, Istanbul, Turkey.

Chorea gravidarum is a rare syndrome in pregnancy. The clinical picture is of extrapyramidal symptoms such as involuntary movements, lack of coordination and slurred speech. Neuroleptics or benzodiazepines can be used for treatment. Read More

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November 2002

Chorea gravidarum.

Arch Neurol 2002 May;59(5):868-70

Department of Neurology and Psychaitry, The Federal University of Minas Gerais, Belo Horizonte, MG, Brazil.

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