264 results match your criteria Chondromyxoid Fibroma Imaging


Benign bony tumors of the paranasal sinuses, orbit, and skull base.

Am J Otolaryngol 2022 May-Jun;43(3):103404. Epub 2022 Feb 26.

Weill Cornell Medical College, Department of Otolaryngology - Head and Neck Surgery, 2315 Broadway, 3rd Floor, New York, NY 10024, United States of America. Electronic address:

Benign bony tumors of the skull base and paranasal sinuses are uncommon entities, with an overall higher incidence in males. Benign bony tumors may lead to local expansion with resultant mass effect of potentially critical structures. Some benign bony tumors may undergo malignant transformation. Read More

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Imaging features of cartilaginous tumors of the head and neck.

J Clin Imaging Sci 2021 4;11:66. Epub 2021 Dec 4.

Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona, United States.

There is a wide spectrum of head and neck cartilaginous lesions which include both neoplastic and nonneoplastic processes. Cartilaginous tumors of the head and neck are uncommon, posing a diagnostic challenge. Benign cartilaginous tumors that may occur in the head and neck include chondroma, chondroblastoma, chondromyxoid fibroma, osteochondroma, and synovial chondromatosis. Read More

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December 2021

Chondromyxoid Fibroma-Like Osteosarcoma in a 13 Years Old Girl: A Report of a New Case.

Clin Pathol 2021 Jan-Dec;14:2632010X211057555. Epub 2021 Nov 18.

Department of Pathology, Maternity and Children's Hospital Ibn Sina University Hospital, Rabat, Morocco.

Osteosarcoma (OS) is the most common primary non hematopoietic malignant tumor of bone with a strict histologic definition: the presence of unequivocal osteoid produced by neoplastic cells. Rare variants displaying low-grade histological features have been described; among which chondromyxoid fibroma-like (CMF-OS) is the rarest. However, despite its bland morphology; CMF-like OS has an aggressive clinical behavior and a poor prognosis. Read More

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November 2021

Craniofacial Chondromyxoid Fibromas: A Systematic Review and Analysis Based on Anatomic Locations.

World Neurosurg 2022 Jun 25;162:21-28. Epub 2021 Oct 25.

Department of Neurosurgery, Mayo Clinic, Phoenix, Arizona, USA; Department of Radiology, Mayo Clinic, Phoenix, Arizona, USA; Department of Otolaryngology, Mayo Clinic, Phoenix, Arizona, USA; Precision Neuro-therapeutics Innovation Lab, Mayo Clinic, Phoenix, Arizona, USA; Neurosurgery Simulation and Innovation Lab, Mayo Clinic, Phoenix, Arizona, USA. Electronic address:

Background: Craniofacial chondromyxoid fibromas (CMFs) are a rare benign tumor of cartilaginous origin. They are commonly misdiagnosed due to the paucity of information on tumor characteristics. We performed a systematic review to characterize CMFs located in different regions of the craniofacial skeleton. Read More

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A Rare Cause of Peripheral Facial Nerve Palsy: Chondromyxoid Fibroma of the Temporal Bone.

J Craniofac Surg 2022 May 14;33(3):e276-e279. Epub 2021 Sep 14.

1st Department of Otorhinolaryngology - Head and Neck Surgery, University of Athens Medical School.

Purpose: To report a rather rare entity of facial palsy due to chondromyxoid fibroma. The authors present a case along with clinico-pathological features, management, treatment options and follow-up.

Methods: The authors present a case of a 29-year-old male who suffered from right facial weakness and numbness for a period of 6-months. Read More

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[Retrofacial approach to remove a rare chondromyxoid fibroma of the infralabyrinthine space].

Vestn Otorinolaringol 2021 ;86(4):106-110

The National Medical Research Center for Otorhinolaryngology of the Federal Medico-Biological Agency of Russia, Moscow, Russia.

A very rare case of 46-yaer-old woman with chondromyxoid fibroma (CMF) of infralabyrinthine area of temporal bone was described in this article. The only manifestation of this disease was a severe temporary pain in the postauricular area with irradiation in the occipital bone and headache during the last 3 months. A detail description of the CT scan and MRI data was presented. Read More

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September 2021

Case report of a female child with right nasal chondromyxoid fibroma.

J Pak Med Assoc 2021 Jul;71(7):1897-1899

Department of Histopathology, Dow University of Health Sciences, Karachi, Pakistan.

Chondromyxoid fibroma is a rare tumour, representing <1% of all primary bone neoplasm. We report the case of a four-year-old female child with a one-year history of nasal obstruction and facial swelling. A large enhanced lesion with amorphous densities spreading into the right cribriform plate and floor of sphenoid sinus, laterally into the right lamina papyracea, inferolaterally into the medial wall of maxillary sinus, posteriorly into the nasopharynx and superior aspect of oropharynx was observed on CT scan. Read More

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A Case Report of Chondromyxoid Fibroma of the Neck of Femur, Intracapsular Location.

J Orthop Case Rep 2021 ;11(1):79-81

Department of Orthopaedics, All India Institute of Medical Sciences, New Delhi, India.

Introduction: Chondromyxoid fibroma (CMF) is an uncommon benign tumor accounts for <2% of all benign and <1% all bone tumors. It is a cartilage tumor with myxoid and fibrous elements. Because of rarity and resemblance with other benign and malignant tumor, diagnosis of this tumor always remains challenging. Read More

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January 2021

Subperiosteal chondromyxoid fibroma: a rare case involving the humeral diaphysis.

Skeletal Radiol 2021 Mar 15;50(3):597-602. Epub 2020 Aug 15.

Department of Radiology, University of Ottawa, Ottawa, ON, K1H 8L6, Canada.

Initially described, in 1948, as a tumor that could be mistaken with chondrosarcoma at histopathology, chondromyxoid fibroma is now a well-recognized entity. Surface-type chondromyxoid fibroma, however, remains an extremely rare occurrence. We present a case of a 55-year-old woman, who experienced right arm pain for 5 years. Read More

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Chondromyxoid Fibroma of the Sacral Spine.

Int J Surg Pathol 2020 Oct 4;28(7):799-803. Epub 2020 May 4.

Rutgers New Jersey Medical School, Newark, NJ, USA.

. Chondromyxoid fibromas are rare tumors of cartilaginous origin typically found in long bones. They usually present during the second and third decades of life. Read More

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October 2020

Chondromyxoid Fibroma of the Mastoid: A Rare Entity with Comprehensive Literature Review.

J Int Adv Otol 2020 Apr;16(1):117-122

Department of Otorhinolaryngology, University Hospital Antwerp, University of Antwerp, Antwerp, Belgium.

Chondromyxoid fibroma (CMF) is the least commonly occurring bone tumor of cartilaginous origin. It is usually situated in the metaphysis of long bones of the lower limbs. Localization of the tumor in the skull is extremely rare. Read More

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Chondromyxoid fibroma of the temporal bone: A rare case report.

Medicine (Baltimore) 2020 Mar;99(11):e19487

Department of Otorhinolaryngology, Beijing Tongren Hospital.

Rationale: Chondromyxoid fibroma (CMF) is a rare form of benign bone tumor and easily misdiagnosed as fibrosarcoma. Hence, to explore the clinical manifestations, diagnostic tests, and therapeutic procedures for temporal bone cartilage myxoid fibroma, it is important to optimize patient treatment and avoid overtreatment. Previous research has discussed cases of CMF, but this paper presents a systematic, complete, and comprehensive introduction of this disease based on this case and related literature. Read More

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Secondary aneurysmal bone cysts and associated primary lesions: imaging features of 49 cases.

Clin Imaging 2020 Jun 30;62:23-32. Epub 2020 Jan 30.

Department of Radiology and Biomedical Imaging, University of California, San Francisco, 505 Parnassus Ave, San Francisco, CA 94143, United States of America.

Purpose: To describe the imaging, anatomic, and clinical features of a series of secondary aneurysmal bone cysts (ABC) and to ascertain their most commonly associated primary bone lesions.

Methods: Forty-nine cases of histopathologically proven secondary ABCs were retrospectively reviewed. Demographic data and clinical history were obtained. Read More

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Chondromyxoid fibroma-like osteosarcoma: a case series and literature review.

BMC Musculoskelet Disord 2020 Jan 29;21(1):53. Epub 2020 Jan 29.

Department of Imaging, Tongren Hospital, Shanghai Jiao Tong University School of Medicine, 1111 Xian Xia Road, Shanghai, 200050, China.

Background: Chondromyxoid fibroma-like osteosarcoma (CMF-OS) is an exceedingly rare subtype of low-grade central osteosarcoma (LGCO), accounting for up to 10% of cases and making it difficult to diagnose. CMF-OS is frequently misdiagnosed on a radiological examination and biopsy, even after the initial operation. Its treatment is a controversial issue due to its low-grade classification and actual high-grade behavior. Read More

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January 2020

Primary chondromyxoid fibroma of the orbit: An orbital mass with calcification.

Indian J Ophthalmol 2019 12;67(12):2110-2113

Department of Ophthalmology, Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India.

Primary orbital chondromyxoid fibroma is a rarely reported entity. A 34-year-old lady presented with painless, non-axial proptosis of the left eye of 6 months duration. Orbital imaging showed a supero-temporal mass with calcific foci and bone erosion. Read More

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December 2019

Chondromyxoid fibroma of the temporal bone: A case report and review of the literature.

World J Clin Cases 2018 Dec;6(16):1210-1216

Department of Radiology, the Affiliated Hospital of Qingdao University, Qingdao 266000, Shandong Province, China.

Background: Chondromyxoid fibroma (CMF) is a rare benign bone tumour of cartilaginous origin, which usually affects the metaphysis of the long bone. Involvement of the temporal bone is extremely rare. Patients with CMF in the temporal bone can present some neurological deficits due to involvement of surrounding neural structures. Read More

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December 2018

Chondromyxoid fibroma with a secondary aneurysmal bone cyst of the distal radius: A case report.

J Orthop Sci 2021 Sep 21;26(5):935-939. Epub 2018 Dec 21.

Department of Orthopaedic Surgery, Faculty of Medicine, Saga University, 5-1-1 Nabeshima, Saga 849-8501, Japan.

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September 2021

Chondromyxoid Fibroma of the Pelvis: Institutional Case Series With a Focus on Distinctive Features.

Int J Surg Pathol 2019 Jun 23;27(4):352-359. Epub 2018 Dec 23.

1 Johns Hopkins University, Baltimore, MD, USA.

Chondromyxoid fibroma (CMF) is a relatively uncommon benign bone tumor of cartilaginous differentiation. The primary pitfall in the histopathologic diagnosis of CMF is confusion with a high-grade chondrosarcoma, owing to the atypical stellate and spindled cells set within a chondromyxoid background. CMF is particularly challenging to diagnose within the pelvis, where clinical suspicion for chondrosarcoma is high and benign lesions may grow to a large size to occupy the pelvic bones. Read More

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Surface-type chondromyxoid fibroma in an elderly patient: a case report and literature review.

Skeletal Radiol 2019 May 29;48(5):823-830. Epub 2018 Nov 29.

Department of Musculoskeletal Radiology, NYU Langone Health, New York, NY, USA.

Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm that typically occurs in young adults. Juxtacortical or surface-type CMF are rarer still and we present the case of a surface-type CMF in a 78-year-old woman, with only one other case described in a patient of a similar age previously. This patient was an otherwise healthy woman who presented for evaluation of a palpable lump in the anterior proximal tibia. Read More

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Huge chondromyxoid fibroma of the right iliac wing with tremendous soft tissue extensions.

BJR Case Rep 2018 21;4(1):20170014. Epub 2017 Oct 21.

Department of Radiology, Benha University, Benha, Egypt.

This report describes a huge chondromyxoid fibroma (CMF) that developed in the right iliac crest and wing. The tumour is rare, perhaps the rarest of all bone tumours, and its occurrence in the iliac crest and wing of a 63-year-old male is extraordinarily uncommon. The patient complained of gradual onset of right groin pain over a period of more than 2 years and low back pain and tender swelling of the right gluteal region over a period of another 1 year. Read More

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October 2017

Peering beneath the surface: Juxtacortical tumors of bone (part I).

Clin Imaging 2018 Sep - Oct;51:1-11. Epub 2018 Feb 3.

Department of Radiology, Cleveland Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA.

Juxtacortical or surface tumors of bone are neoplasms arising from or just outside the cortex, and are composed of different histologic types. Although the imaging appearances of these lesions have similarities to their intramedullary counterparts, their location alters their radiographic and MR characteristics, creating difficulties in diagnosis. Meanwhile, several non-neoplastic lesions, such as stress reaction/stress fracture and indolent infectious processes, compound the differential diagnosis. Read More

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December 2018

Benign Chondromyxoid Fibroma of the Iliac Crest.

J Orthop Sports Phys Ther 2018 02;48(2):122

A 23-year-old woman initiated a running program and after 2 months began experiencing right hip joint pain and sharp pain at the iliac crest. Following evaluation by her primary care physician, she was referred to a physical therapist. Eighteen months later, the patient had developed a bony prominence at the iliac crest that was painful to touch. Read More

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February 2018

Peering beneath the surface: juxtacortical tumors of bone (part II).

Clin Imaging 2018 Jul - Aug;50:113-122. Epub 2018 Jan 11.

Department of Radiology, Cleveland Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA.

Juxtacortical or surface tumors of bone are neoplasms arising from or just outside the cortex, and are composed of different histologic types. Although the imaging appearances of these lesions have similarities to their intramedullary counterparts, their location alters their radiographic and MR characteristics, creating difficulties in diagnosis. Meanwhile, several non-neoplastic lesions, such as stress reaction/stress fracture and indolent infectious processes, compound the differential diagnosis. Read More

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October 2018

Chondromyxoid Fibroma Arising in Craniofacial Sites: A Clinicopathologic Analysis of 25 Cases.

Am J Surg Pathol 2018 03;42(3):392-400

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

Chondromyxoid fibroma (CMF) is a rare benign tumor, usually arising in the metaphysis of long bones in young adults. Occurrence in craniofacial bones presents a particular diagnostic challenge given its unusual location and resemblance to malignant mimics. We describe the clinicopathologic features of 25 cases of craniofacial CMF identified between 1999 and 2017. Read More

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Radiological presentation of chondromyxoid fibroma in the sellar region: A CARE-compliant article and literature review.

Medicine (Baltimore) 2017 Dec;96(49):e9049

Department of Neurology, Shengjing Hospital of China Medical University, Shenyang, Liao Ning, China Department of Pathology, Duke University Medical Center, Durham, NC Department of Pathology, First Affiliated Hospital of China Medical University and College of Basic Medical Sciences, Shenyang, Liao Ning, China.

Rationale: Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm which often occurs in the lower extremities. Little is known about the radiological and histological presentation of CMF in the sellar region.

Patient Concerns: A 16-year-old Asian male presented to the hospital 12 months ago with bilateral diplopia involving right visual fields, intermittent headaches, and dizziness. Read More

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December 2017

Preliminary Exploration of the Diagnosis and Treatment of Skull-Based Chondromyxoid Fibromas.

Oper Neurosurg (Hagerstown) 2018 09;15(3):270-277

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.

Background: Chondromyxoid fibromas (CMFs) are benign tumors that occur rarely in the skull base.

Objective: To conduct a preliminary exploration of the diagnosis and treatment of cranial CMFs.

Methods: A retrospective analysis of 19 cases of CMFs in the base of the skull between 2009 and 2014 in our hospital was conducted. Read More

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September 2018

An intracortical chondromyxoid fibroma in the diaphysis of the metatarsal.

Skeletal Radiol 2017 Dec 15;46(12):1757-1762. Epub 2017 Aug 15.

Department of Pathology, Korea University Ansan Hospital, Ansan-si, Republic of Korea.

Chondromyxoid fibromas (CMFs) are rare, benign, primary tumors of bones, and occur in the metaphyses of the medullary canals of the long bones. The occurrence of intracortical CMFs is extremely rare. Very few cases of intracortical CMFs located in the long tubular bones have been reported to date. Read More

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December 2017

Chondromyxoid fibroma of the distal fibula treated by percutaneous radiofrequency ablation.

J Orthop Surg (Hong Kong) 2017 May-Aug;25(2):2309499017720830

4 Department of Orthopedic Surgery, Hadassah-Hebrew University School of Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.

Background: Percutaneous radiofrequency ablation (RFA) has been shown to be an effective treatment for soft tissue lesions and also benign bone tumors, especially osteoid osteoma. There are limited data regarding this technique in other bone tumors, specifically larger and more aggressive ones.

Purposes: To describe the use of RFA as a definitive treatment and an alternative to traditional open surgery for the treatment of chondromyxoid fibroma (CMF), a benign but locally aggressive bone tumor. Read More

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Benign Bone Conditions That May Be FDG-avid and Mimic Malignancy.

Semin Nucl Med 2017 07 12;47(4):322-351. Epub 2017 Apr 12.

Department of Radiology and Nuclear Medicine, Deventer Ziekenhuis, Deventer, The Netherlands.

Positron emission tomography with the radiotracer F-fluoro-2-deoxy-d-glucose (FDG) plays an important role in the evaluation of bone pathology. However, FDG is not a cancer-specific agent, and knowledge of the differential diagnosis of benign FDG-avid bone alterations that may resemble malignancy is important for correct patient management, including the avoidance of unnecessary additional invasive tests such as bone biopsy. This review summarizes and illustrates the spectrum of benign bone conditions that may be FDG-avid and mimic malignancy, including osteomyelitis, bone lesions due to benign systemic diseases (Brown tumor, Erdheim-Chester disease, Gaucher disease, gout and other types of arthritis, Langerhans cell histiocytosis, and sarcoidosis), benign primary bone lesions (bone cysts, chondroblastoma, chondromyxoid fibroma, desmoplastic fibroma, enchondroma, giant cell tumor and granuloma, hemangioma, nonossifying fibroma, and osteoid osteoma and osteoblastoma), and a group of miscellaneous benign bone conditions (post bone marrow biopsy or harvest status, bone marrow hyperplasia, fibrous dysplasia, fractures, osteonecrosis, Paget disease of bone, particle disease, and Schmorl nodes). Read More

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[Chondromyxoid fibroma of the mandible: a case report].

Hua Xi Kou Qiang Yi Xue Za Zhi 2016 Dec;34(6):654-656

Dept. of Oral and Maxillofacial Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.

Chondromyxoid fibroma (CMF) is a rare benign bone tumor. This tumor mostly affects the long bones of the appendicular skeleton but rarely grows in the craniofacial region. In this article, a case of CMF of the mandible was presented to enhance our understanding of CMF. Read More

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December 2016