671 results match your criteria Chondromyxoid Fibroma


Surface-type chondromyxoid fibroma in an elderly patient: a case report and literature review.

Skeletal Radiol 2018 Nov 29. Epub 2018 Nov 29.

Department of Musculoskeletal Radiology, NYU Langone Health, New York, NY, USA.

Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm that typically occurs in young adults. Juxtacortical or surface-type CMF are rarer still and we present the case of a surface-type CMF in a 78-year-old woman, with only one other case described in a patient of a similar age previously. This patient was an otherwise healthy woman who presented for evaluation of a palpable lump in the anterior proximal tibia. Read More

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November 2018

Huge chondromyxoid fibroma of the right iliac wing with tremendous soft tissue extensions.

BJR Case Rep 2018 21;4(1):20170014. Epub 2017 Oct 21.

Department of Radiology, Benha University, Benha, Egypt.

This report describes a huge chondromyxoid fibroma (CMF) that developed in the right iliac crest and wing. The tumour is rare, perhaps the rarest of all bone tumours, and its occurrence in the iliac crest and wing of a 63-year-old male is extraordinarily uncommon. The patient complained of gradual onset of right groin pain over a period of more than 2 years and low back pain and tender swelling of the right gluteal region over a period of another 1 year. Read More

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October 2017
4 Reads

Fine-needle aspiration features of extraskeletal myxoid chondrosarcoma: A study of cytological and molecular features.

Diagn Cytopathol 2018 Nov 24;46(11):950-957. Epub 2018 Oct 24.

Serviço de Anatomia Patológica, Instituto Português de Oncologia de Lisboa Francisco Gentil, Lisbon, Portugal.

Background: Extraskeletal myxoid chondrosarcoma (EMC) is a tumor of uncertain differentiation. Few data are available regarding its cytomorphological features in fine-needle aspiration (FNA). Specific cytogenetic alterations involving the NR4A3 gene are found in EMC and can be identified in FNA samples. Read More

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November 2018
1 Read

Histone H3K36M mutation and trimethylation patterns in chondroblastoma.

Histopathology 2018 Aug 11. Epub 2018 Aug 11.

Department of Pathology, Memorial Sloan Kettering Cancer Center, Great Neck, NY, USA.

Aims: Histones are essential components of chromatin, and mutations in histones lead to alterations in methylation and acetylation, which play an important role in tumorigenesis. Most of the chondroblastomas harbour the H3K36M mutation. With the availability of a mutation-specific antibody, we sought to assess the sensitivity of this antibody and the alterations of histone methylation in a series of chondroblastoma cases. Read More

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August 2018
13 Reads

Treatment of cryotherapy and orthotopic transplantation following chondromyxoid fibroma of zygomatic bone: A case report.

Medicine (Baltimore) 2018 Aug;97(31):e11707

Department of Oral, Maxillofacial, Cephalic and Cervical Tumors, Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine, Huangpu District, Shanghai, China.

Introduction: Chondromyxoid fibrotherma (CMF) is a rare benign cartilage tumor that occurs more frequently in young males at the age of 20 to 30. It occurs more frequently on long bones, but rarely involves craniofacial bones.

Case Presentation: This study mainly introduced a 30-year-old male with CMF of zygomatic bone. Read More

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August 2018
3 Reads

Ear and Temporal Bone: Cartilaginous and Osseous Pathologies.

Head Neck Pathol 2018 Sep 1;12(3):378-391. Epub 2018 Aug 1.

Department of Pathology, Division of Pathology & Laboratory Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.

Although the majority of conditions involving the ear and temporal bone are inflammatory or epithelial based, cartilage and osseous entities will also be encountered. The pathologic examination of these underlying cartilaginous and osseous structures and their histologic findings and associated differential diagnoses will be discussed. Correlation with clinical and imaging findings are also critical for accurate determination of the pathologic entity. Read More

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September 2018
1 Read

Phosphaturic mesenchymal tumor, an unusual localization in head and neck.

J Surg Case Rep 2018 May 22;2018(5):rjy091. Epub 2018 May 22.

Maxillo-Facial Unit, Policlinico A. Gemelli, Università Cattolica del Sacro Cuore, Largo Agostino Gemelli, 8, 00168 Rome, Italy.

Phosphaturic mesenchymal tumor (PMT) is a rare mesenchymal neoplasm associated with tumor-induced osteomalacia involving bone and soft tissue that produces paraneoplastic hypophosphatemic osteomalacia. The common physiologic defect in this conditions involves an impairment in renal tubular phosphate reabsorption with a downregulation of renal 1α-hydroxylase activity, while calcium metabolism remains essentially unaffected. Microscopic features consist of spindle cells, multinucleated giant cells and calcifications embedded in a chondromyxoid matrix with variable cellularity and prominent vascularity. Read More

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May 2018
9 Reads

Ectomesenchymal Chondromyxoid Tumor: A Neoplasm Characterized by Recurrent RREB1-MKL2 Fusions.

Am J Surg Pathol 2018 Oct;42(10):1297-1305

Department of Pathology, UT Southwestern Medical Center, Dallas, TX.

Ectomesenchymal chondromyxoid tumor is a rare and benign neoplasm with a predilection for the anterior dorsal tongue. Despite morphologic heterogeneity, most cases are characterized by a proliferation of bland spindle cells with a distinctive reticular growth pattern and myxoid stroma. The immunophenotype of these neoplasms is likewise variable; most cases express glial fibrillary acid protein and S100 protein, with inconsistent reports of keratin and myoid marker expression. Read More

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October 2018
7 Reads

[Effectiveness of unicompartment allografts replacement for bone tumor around the knee].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2017 Aug;31(8):908-912

Department of Orthopaedics, General Hospital of Chinese PLA, Beijing, 100853, P.R.China.

Objective: To analyze the effectiveness of unicompartment allografts replacement for reconstructing bone defect after bone tumor resection around knee.

Methods: Between January 2007 and January 2014, a total of 9 patients received unicompartment allografts replacement to treat bone tumor around the knee, including 6 males and 3 females, with an average age of 25.8 years (range, 17-38 years). Read More

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Fine needle aspiration cytology finding of a parotid mass with chondromyxoid matrix and variable epithelial cytological atypia.

Authors:
Hyun-Jung Kim

Cytojournal 2018 2;15:10. Epub 2018 Apr 2.

Address: Department of Pathology, Inje University, Sanggye -Paik Hospital, Seoul, Korea.

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Immune cell infiltration in Ectomesenchymal chondromyxoid tumor: An immunohistochemical study.

Oral Oncol 2018 Jun;81:112-115

Oral Pathology, Department of Stomatology, Public Oral Health and Forensic Dentistry, School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto, Brazil. Electronic address:

Ectomesenchymal chondromyxoid tumor (ECT) is a rare benign neoplasm, often affecting the anterior dorsum of the tongue. To date, approximately 74 cases of lingual ECT have been published. This report describes, for the first time, the morphological and immunohistochemical features of a unique ECT case, which revealed diffuse infiltration by immune cells with a dendritic-like appearance inside the tumor proliferation. Read More

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June 2018
1 Read

A case report on partial scapulectomy with glenoid preservation for Chondromyxoid fibroma of scapula.

J Clin Orthop Trauma 2018 Mar 28;9(Suppl 1):S129-S135. Epub 2017 Dec 28.

Professor, Department of Orthopaedics, Assam Medical College & Hospital, Dibrugarh, Assam, India.

Chondromyxoid fibroma is a benign bone tumour accounting for less than 1% of all primary bone tumours. It usually affects the metaphyseal region of long bones in the first or second decade of life. It rarely occurs in scapula. Read More

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March 2018
2 Reads

Liquid-based cytology versus conventional cytology in fine-needle aspirates of salivary gland neoplasms.

Indian J Pathol Microbiol 2018 Jan-Mar;61(1):45-49

Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India.

Background: Liquid-based cytology (LBC) is a method of retrieving and processing of cytological material for the assessment of both gynecological and nongynecological cases introduced in 1996. Mostly conventional smears (CS) are prepared in Indian scenario; however, due to increasing popularity of LBC in nongynecology specimens, LBC is also used in few centers for diagnosing salivary gland neoplasm.

Aim: The aim of this study is to compare CS and LBC in fine-needle aspiration cytology (FNAC) of the salivary gland neoplasms in terms of cytomorphological details, adequacy, ease of interpretation, pitfalls, and diagnostic efficiency. Read More

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November 2018
5 Reads
0.640 Impact Factor

Fluorescent In Situ Hybridization for TP53 in the Diagnosis of Pediatric Osteogenic Sarcoma.

Am J Surg Pathol 2018 Jun;42(6):744-749

Division of Pathology.

Osteogenic sarcoma (OS) is the most common malignant bone tumor in children and adolescents. Despite advances in molecular genetic characterization of pediatric and adult tumors, the diagnosis of OS still depends almost entirely on light microscopy. The lack of consistent genetic changes in OS has greatly hindered the development of any diagnostic molecular test. Read More

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June 2018
7 Reads

A Case of a Malignant Cutaneous Mixed Tumor (Chondroid Syringoma) of the Scapula Treated With Staged Margin-Controlled Excision.

Am J Dermatopathol 2018 Sep;40(9):679-681

Pathology, University of Massachusetts Medical School, Worcester, MA.

Cutaneous mixed tumor (chondroid syringoma) is the cutaneous counterpart of pleomorphic adenoma of salivary glands, comprised of both epithelial and mesenchymal components. Malignant transformation is exceptionally rare, with only a few cases reported. We report a case of a malignant cutaneous mixed tumor in an 86-year-old white man who presented with a pink indurated plaque on his left scapula. Read More

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September 2018
15 Reads

Ectomesenchymal chondromyxoid tumor: a comprehensive updated review of the literature and case report.

Int J Oral Sci 2018 02 28;10(1). Epub 2018 Feb 28.

IMAH, Institute of Morphological Analytics and Human Genetics, Grabenstraße 23, 8010, Graz, Austria.

Prompted by a unique case of an ectomesenchymal chondromyxoid tumor (ECT) of the palate in a 54-year-old female, we reviewed the English and German literature on this entity until the end of 2016 using PubMed. The search produced 74 lingual cases with a nearly equal sex distribution and a mean age of 39.3 years, and two extra-lingual cases sharing histological and immunohistological features including nodular growth, round, fusiform or spindle-shaped cellular architecture, and chondromyxoid stroma. Read More

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February 2018
8 Reads

Peering beneath the surface: Juxtacortical tumors of bone (part I).

Clin Imaging 2018 Sep - Oct;51:1-11. Epub 2018 Feb 3.

Department of Radiology, Cleveland Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA.

Juxtacortical or surface tumors of bone are neoplasms arising from or just outside the cortex, and are composed of different histologic types. Although the imaging appearances of these lesions have similarities to their intramedullary counterparts, their location alters their radiographic and MR characteristics, creating difficulties in diagnosis. Meanwhile, several non-neoplastic lesions, such as stress reaction/stress fracture and indolent infectious processes, compound the differential diagnosis. Read More

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December 2018
15 Reads

Chondromyxoid Fibroma of the Metatarsal Bone: A Diagnosis Using Fine Needle Aspiration Biopsy.

J Cytol 2018 Jan-Mar;35(1):67-68

Department of Orthpaedics, Andaman and Nicobar Islands Institute of Medical Sciences, Port Blair, India.

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February 2018
3 Reads

Malignant Ewing-Like Neoplasm With an EWSR1-KLF15 Fusion: At the Crossroads of a Myoepithelial Carcinoma and a Ewing-Like Sarcoma. A Case Report With Treatment Options.

Int J Surg Pathol 2018 Aug 1;26(5):440-447. Epub 2018 Feb 1.

1 University of Alabama at Birmingham, AL, USA.

We present a case of a malignant Ewing-like neoplasm of the parotid gland in a 20-year-old woman with an EWSR1-KLF15 gene fusion that presented with pulmonary metastasis. Despite the fact that the tumor was essentially immunohistochemically negative for keratins, p63, and p40, we interpret this neoplasm as an unusual form of a high-grade myoepithelial carcinoma based on its focal plasmacytoid cytology, chondromyxoid matrix, SOX10, S100 protein, and calponin expression, and the knowledge that the EWSR1-KLF15 gene fusion has, to date, only been identified in 2 tumors, both myoepithelial carcinomas of the kidney. We also present a cytogenetic analysis of this unusual tumor. Read More

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August 2018
10 Reads

Benign Chondromyxoid Fibroma of the Iliac Crest.

J Orthop Sports Phys Ther 2018 Feb;48(2):122

A 23-year-old woman initiated a running program and after 2 months began experiencing right hip joint pain and sharp pain at the iliac crest. Following evaluation by her primary care physician, she was referred to a physical therapist. Eighteen months later, the patient had developed a bony prominence at the iliac crest that was painful to touch. Read More

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February 2018
5 Reads

Peering beneath the surface: juxtacortical tumors of bone (part II).

Clin Imaging 2018 Jul - Aug;50:113-122. Epub 2018 Jan 11.

Department of Radiology, Cleveland Medical Center, University Hospitals of Cleveland, Case Western Reserve University, Cleveland, OH, USA.

Juxtacortical or surface tumors of bone are neoplasms arising from or just outside the cortex, and are composed of different histologic types. Although the imaging appearances of these lesions have similarities to their intramedullary counterparts, their location alters their radiographic and MR characteristics, creating difficulties in diagnosis. Meanwhile, several non-neoplastic lesions, such as stress reaction/stress fracture and indolent infectious processes, compound the differential diagnosis. Read More

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October 2018
13 Reads

Chondromyxoid Fibroma Arising in Craniofacial Sites: A Clinicopathologic Analysis of 25 Cases.

Am J Surg Pathol 2018 Mar;42(3):392-400

Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, MA.

Chondromyxoid fibroma (CMF) is a rare benign tumor, usually arising in the metaphysis of long bones in young adults. Occurrence in craniofacial bones presents a particular diagnostic challenge given its unusual location and resemblance to malignant mimics. We describe the clinicopathologic features of 25 cases of craniofacial CMF identified between 1999 and 2017. Read More

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March 2018
6 Reads

Matrix-producing metaplastic breast carcinoma - a rare tumor with heterologous elements.

Ger Med Sci 2017 6;15:Doc17. Epub 2017 Dec 6.

National Institute of Pathology (ICMR), Safdarjung Hospital Campus, New Delhi, India.

Metaplastic breast carcinomas are ductal carcinomas that undergo metaplasia into non-glandular growth patterns. They are very rare and account for less than 1% of all invasive breast carcinomas. Matrix-producing carcinoma is an extremely rare and aggressive subtype of metaplastic breast carcinoma that is characterized by a ductal carcinomatous component with direct transition to areas with cartilaginous/osseous differentiation without an intervening spindle cell element. Read More

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August 2018
1 Read

Radiological presentation of chondromyxoid fibroma in the sellar region: A CARE-compliant article and literature review.

Medicine (Baltimore) 2017 Dec;96(49):e9049

aDepartment of Neurology, Shengjing Hospital of China Medical University, Shenyang, Liao Ning, ChinabDepartment of Pathology, Duke University Medical Center, Durham, NCcDepartment of Pathology, First Affiliated Hospital of China Medical University and College of Basic Medical Sciences, Shenyang, Liao Ning, China.

Rationale: Chondromyxoid fibroma (CMF) is a rare benign bone neoplasm which often occurs in the lower extremities. Little is known about the radiological and histological presentation of CMF in the sellar region.

Patient Concerns: A 16-year-old Asian male presented to the hospital 12 months ago with bilateral diplopia involving right visual fields, intermittent headaches, and dizziness. Read More

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December 2017
14 Reads

Preliminary Exploration of the Diagnosis and Treatment of Skull-Based Chondromyxoid Fibromas.

Oper Neurosurg (Hagerstown) 2018 Sep;15(3):270-277

Department of Neurosurgery, Huashan Hospital, Fudan University, Shanghai, China.

Background: Chondromyxoid fibromas (CMFs) are benign tumors that occur rarely in the skull base.

Objective: To conduct a preliminary exploration of the diagnosis and treatment of cranial CMFs.

Methods: A retrospective analysis of 19 cases of CMFs in the base of the skull between 2009 and 2014 in our hospital was conducted. Read More

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September 2018
5 Reads

Ectomesenchymal chondromyxoid neoplasm. An unusual presentation. A case report.

Int J Surg Case Rep 2017 25;41:162-164. Epub 2017 Oct 25.

ENT Deptt., Al-Farwaniya Hospital, Kuwait.

Ectomesenchymal chondromyxoid tumor (ECMT) is a rare benign intraoral tumor. Clinically, it presents as a slow growing, painless, firm, submucosal swelling exclusively occurring on the anterior dorsum of the tongue. Till date not more than 45 cases have been reported in literature. Read More

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October 2017
1 Read

Long-lasting chondromyxoid fibroma of the zygoma: A rare case report and review of literature.

J Educ Health Promot 2017 9;6:78. Epub 2017 Aug 9.

Department of Otolaryngology, Clinical Pathology Division, Department of Pathology, School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran.

Chondromyxoid fibroma (CMF) is a benign tumor which usually occurs in skeletal long bones. Its presence in zygoma is extremely rare. The patient was a 47-year-old female, with chief complaint of painful swelling in the left side of zygoma since 1 month ago after a long-lasting painless swelling for about 15 years. Read More

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August 2017
11 Reads

An intracortical chondromyxoid fibroma in the diaphysis of the metatarsal.

Skeletal Radiol 2017 Dec 15;46(12):1757-1762. Epub 2017 Aug 15.

Department of Pathology, Korea University Ansan Hospital, Ansan-si, Republic of Korea.

Chondromyxoid fibromas (CMFs) are rare, benign, primary tumors of bones, and occur in the metaphyses of the medullary canals of the long bones. The occurrence of intracortical CMFs is extremely rare. Very few cases of intracortical CMFs located in the long tubular bones have been reported to date. Read More

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December 2017
3 Reads

Case of chondroid syringoma mimicking a nodular hidradenoma: A diagnostic pitfall on cytopathology.

Diagn Cytopathol 2018 Jan 3;46(1):59-62. Epub 2017 Aug 3.

Department of Pathology, North Delhi Municipal Corporation Medical College and Hindu Rao Hospital, New Delhi, India.

Limited literature is available on the use of fine needle aspiration (FNA) for skin tumors. Awareness of cytological features of these lesions is important to prevent misdiagnosis. A 45-year-old male, presented with slowly growing swelling over the thigh since 4 years. Read More

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January 2018
4 Reads

Chondromyxoid fibroma of the distal fibula treated by percutaneous radiofrequency ablation.

J Orthop Surg (Hong Kong) 2017 May-Aug;25(2):2309499017720830

4 Department of Orthopedic Surgery, Hadassah-Hebrew University School of Medicine, Shaare Zedek Medical Center, Jerusalem, Israel.

Background: Percutaneous radiofrequency ablation (RFA) has been shown to be an effective treatment for soft tissue lesions and also benign bone tumors, especially osteoid osteoma. There are limited data regarding this technique in other bone tumors, specifically larger and more aggressive ones.

Purposes: To describe the use of RFA as a definitive treatment and an alternative to traditional open surgery for the treatment of chondromyxoid fibroma (CMF), a benign but locally aggressive bone tumor. Read More

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March 2018
4 Reads

[Rare location of chondromyxoid fibroma: about a case].

Pan Afr Med J 2017;26:219. Epub 2017 Apr 24.

Service de Chirurgie Orthopédique et de Traumatologie, CHU Ibn Sina, Université Mohammed V Souissi, Rabat, Maroc.

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February 2018
6 Reads

A rare benign tumor of breast masquerading on fine needle aspiration cytology: A case report.

Breast Dis 2017 ;37(2):105-107

Pleomorphic adenoma is a common tumor encountered in major salivary gland and very rarely seen in breast. This matrix producing tumor can be confused with fibroadenoma, phyllodes tumor and metaplastic carcinoma on fine needle aspiration cytology(FNAC). Pre-operative diagnosis of pleomorphic adenoma helps in preventing surgical over or under treatment of the disease. Read More

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September 2018
11 Reads

Combined Use of Mammography and FNA Eliminates Pitfalls in the Management of Metaplastic Breast Carcinoma.

In Vivo 2017 Jul-Aug;31(4):737-740

Department of Cytopathology, Hygeia Hospital, Athens, Greece.

Background: Due to its heterogeneity, metaplastic breast carcinoma (MBC) poses diagnostic dilemmas, leading to delayed treatment, thereby aggravating the prognosis. Over the years, there has been controversy regarding the role of fine-needle aspiration (FNA) cytology in timely diagnosis.

Case Report: A 54-year-old woman presented with a palpable mass in the upper outer quadrant of her right breast with corresponding mammographic findings and FNA was performed. Read More

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March 2018
11 Reads
1.150 Impact Factor

Phosphaturic Mesenchymal Tumors: Clinicopathologic, Immunohistochemical and Molecular Analysis of 22 Cases Expanding their Morphologic and Immunophenotypic Spectrum.

Am J Surg Pathol 2017 Oct;41(10):1371-1380

*Institute of Pathology ††Department of Hand & Plastic Surgery, University Hospital, Erlangen **Institute of Pathology ‡‡Department of Orthopedic & Traumatology, Section for Tumor Orthopedics, University Hospital, Bonn, Germany †Department of Pathology, Faculty of Medicine in Pilsen, Charles University, Prague ‡Biomedical Center of the Faculty of Medicine in Pilsen, Pilsen, Czech Republic §Department of Pathology, University of Pittsburgh Medical Center, Presbyterian Hospital, Pittsburgh, PA ∥Department of Pathology, National University Health System, Singapore ¶Department of Pathology, 3rd Medical Faculty in Prague, Charles University, Prague, Czech Republic.

Phosphaturic mesenchymal tumor (PMT) is a rare neoplasm of uncertain histogenesis that has been linked to tumor-induced osteomalacia (TIO) since 1959. The neoplastic cells produce increased amount of FGF23 which results in TIO via uncontrolled renal loss of phosphate (phosphaturia), and consequently diminished bone mineralization. To date, ∼300 cases have been reported. Read More

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October 2017
15 Reads

Benign Bone Conditions That May Be FDG-avid and Mimic Malignancy.

Semin Nucl Med 2017 07 12;47(4):322-351. Epub 2017 Apr 12.

Department of Radiology and Nuclear Medicine, Deventer Ziekenhuis, Deventer, The Netherlands.

Positron emission tomography with the radiotracer F-fluoro-2-deoxy-d-glucose (FDG) plays an important role in the evaluation of bone pathology. However, FDG is not a cancer-specific agent, and knowledge of the differential diagnosis of benign FDG-avid bone alterations that may resemble malignancy is important for correct patient management, including the avoidance of unnecessary additional invasive tests such as bone biopsy. This review summarizes and illustrates the spectrum of benign bone conditions that may be FDG-avid and mimic malignancy, including osteomyelitis, bone lesions due to benign systemic diseases (Brown tumor, Erdheim-Chester disease, Gaucher disease, gout and other types of arthritis, Langerhans cell histiocytosis, and sarcoidosis), benign primary bone lesions (bone cysts, chondroblastoma, chondromyxoid fibroma, desmoplastic fibroma, enchondroma, giant cell tumor and granuloma, hemangioma, nonossifying fibroma, and osteoid osteoma and osteoblastoma), and a group of miscellaneous benign bone conditions (post bone marrow biopsy or harvest status, bone marrow hyperplasia, fibrous dysplasia, fractures, osteonecrosis, Paget disease of bone, particle disease, and Schmorl nodes). Read More

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July 2017
25 Reads

Basal Cell Adenoma of Retromolar Region from Minor Salivary Gland Origin in a 45-Year-Old Female: A Case Report.

Craniomaxillofac Trauma Reconstr 2017 Jun 18;10(2):162-165. Epub 2016 Jul 18.

Department of Dentistry and Faciomaxillary Surgery, K.C. Multispeciality Hospital, Chennai, Tamil Nadu, India.

Basal cell adenoma is a rare benign salivary gland neoplasm. The most common location is in parotid region. Clinically, gradual growth and firm consistency are seen. Read More

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June 2017
15 Reads

Myoepithelial Carcinoma of the Paracecal Mesentery: Aggressive Behavior of a Rare Neoplasm at an Unusual Anatomic Site.

Rare Tumors 2017 Mar 31;9(1):6504. Epub 2017 Mar 31.

Sarcoma Unit, Royal Marsden NHS Foundation Trust, London.

Myoepithelial tumors of the soft tissues represent a rare group of neoplasms that vary in their clinical behavior, pathologic features and genetics. They are histopathologically typified by a immunohistochemical phenotype, of expression of one or more epithelial markers, S100 protein and smooth muscle actin. Because of their rarity and occurrence over a wide age range and at a variety of anatomic sites, they can be difficult to diagnose due to the lack of familiarity by physicians, which is compounded by their spectrum of histologic features and morphologic overlap with several other neoplasms. Read More

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March 2017
9 Reads

Metaplastic Carcinoma With Extensive Chondromyxoid Differentiation Arising in Association With Microglandular Adenosis.

Int J Surg Pathol 2017 Sep 1;25(6):513-514. Epub 2017 Mar 1.

1 University of Michigan, Ann Arbor, MI, USA.

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September 2017

Multiple Calcifying Pseudoneoplasms of the Neuraxis.

Cureus 2017 Feb 21;9(2):e1044. Epub 2017 Feb 21.

Neurosurgery / Neuro Oncology Program, Mayo Clinic, Jacksonville, FL.

Calcifying pseudoneoplasms of the neuraxis (CAPNONs) are extremely rare tumors that are frequently misdiagnosed and overlooked by clinicians. To date, only 40 intracranial lesions have been reported, and in all instances, they were found as a solitary calcified mass. To our knowledge, the current case report is the first to illustrate the development of multiple intraaxial CAPNONs and shed more light on the origin of these lesions. Read More

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February 2017
2 Reads

Clinical features of ectomesenchymal chondromyxoid tumors: A systematic review of the literature.

Oral Oncol 2017 04 8;67:192-197. Epub 2017 Mar 8.

Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, 135 Rutledge Avenue, MSC 550, Charleston, SC 29425, USA. Electronic address:

Ectomesenchymal chondromyxoid tumors are rare, benign neoplasms of the head and neck most commonly found within the oral cavity. While histopathological evaluation has been the primary focus of prior studies, clinical characterization of this rare entity currently remains sparse. Thus, this study was performed to provide insights into the clinical characteristics of ectomesenchymal chondromyxoid tumors to aid clinicians in distinguishing the lesion from other benign and malignant processes for a more accurate diagnosis and treatment. Read More

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April 2017
8 Reads

[Chondromyxoid fibroma of the mandible: a case report].

Hua Xi Kou Qiang Yi Xue Za Zhi 2016 Dec;34(6):654-656

Dept. of Oral and Maxillofacial Surgery, General Hospital of Ningxia Medical University, Yinchuan 750004, China.

Chondromyxoid fibroma (CMF) is a rare benign bone tumor. This tumor mostly affects the long bones of the appendicular skeleton but rarely grows in the craniofacial region. In this article, a case of CMF of the mandible was presented to enhance our understanding of CMF. Read More

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December 2016
6 Reads

Carcinoma ex pleomorphic adenoma: A diagnostic challenge on cytology.

Diagn Cytopathol 2017 Jul 6;45(7):651-654. Epub 2017 Mar 6.

Department of Pathology, ESIC Medical College, Faridabad, Haryana, India.

Carcinoma ex pleomorphic adenoma (Ca ex PA) is a malignant neoplasm arising from primary or recurrent benign pleomorphic adenoma. It is rare with an annual incidence rate of 0.17 tumors per million. Read More

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July 2017
7 Reads

Chondromyxoid Fibroma of the Skull Base: Our Experience with an Elusive Disease.

J Neurol Surg A Cent Eur Neurosurg 2017 Nov 2;78(6):576-581. Epub 2017 Mar 2.

Rome Army Hospital "Celio," Neurosurgery Division, Sapienza University Rome, Dipartimento Scienze Neurosensoriali, Rome, Italy.

Chondromyxoid fibroma (CMF) is an extremely rare lesion of the skull base. This histologic type typically predilects metaphysis of the long bones. It is locally invasive/infiltrative, and this tendency is more concerning in the skull base, where a radical resection is often technically impossible because of the presence of vital neurovascular structures. Read More

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November 2017
3 Reads

Primary Orbital Chondromyxoid Fibroma: A Rare Case.

Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S114-S116

Departments of *Ophthalmology and †Neurosurgery, Maywood, Illinois, U.S.A.

A 56-year-old male with history of chronic sinusitis was found to have a 3 cm left orbital lesion on CT. Subsequent MRI demonstrated a multilobulated enhancing soft tissue lesion at the superotemporal region of the left orbit. Initial biopsy was reported as a low-grade sarcoma. Read More

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September 2017
6 Reads

Exceptional Rare Giant Craniofacial Chondroid Tumor in Adult.

World Neurosurg 2017 Feb 18;98:867.e1-867.e3. Epub 2016 Dec 18.

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China. Electronic address:

We present a rare case of giant soap bubble-shaped cystic lesion in the craniofacial region in an adult female. Histopathologic examination revealed the tumor consisted of 3 components including chondroblastoma, chondromyxoid fibroma, and hemorrhagic aneurysmal bone cyst. The present case is rare in terms of size, location, and histopathologic diagnosis, which is probably the result of underdeveloped health care in the remote place. Read More

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February 2017
10 Reads

Pleomorphic Adenoma of the Eyelid with Apocrine Gland Origin; an Atypical Location.

J Ophthalmic Vis Res 2016 Oct-Dec;11(4):439-441

Department of Ophthalmology, Vila Nova de Gaia/Espinho Hospital Centre, Portugal.

Purpose: To describe the clinical presentation and treatment of a patient with a cutaneous pleomorphic adenoma of the eyelid.

Case Report: A 73-year-old male patient presented with a nodular mass on the lateral third of his right upper eyelid, which had slowly enlarged over 10 years. Radiologic features were of an extra-conical mass, with no invasion of adjacent structures. Read More

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December 2016

Pediatric Chondromyxoid Fibroma-Like Osteosarcoma.

Fetal Pediatr Pathol 2017 Apr 9;36(2):154-161. Epub 2016 Dec 9.

a Department of Pathology , Children's Hospital New Orleans , New Orleans , LA , USA.

Chondromyxoid fibroma-like osteosarcoma (CMF-OS) is a low-grade osteosarcoma, often misdiagnosed on initial biopsy as a benign lesion, with five cases previously described. We report a 13-year-old male with an intramedullary lytic CMF-OS of the right tibial proximal metaphysis with cortical destruction and soft tissue extension. Diagnosis was based on malignant new bone formation, increased mitotic figures, lamellar bone permeation with bony destruction, and correlation with imaging studies. Read More

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April 2017
7 Reads

Chondromyxoid Fibroma: A Rare Case Report and Review of Literature.

Cureus 2016 Sep 23;8(9):e803. Epub 2016 Sep 23.

Orthopaedics, Sumandeep Vidyapeeth, Vadodara, Gujarat.

Chondromyxoid fibroma (CMF) is one of the rarest benign tumors of cartilaginous origin. It accounts for less than 0.5% of bone tumors and less than two percent of benign bone tumors. Read More

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September 2016
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Cytodiagnosis of ChondromyxoidFibroma of the Metatarsal Head: A Case Report.

Iran J Pathol 2016 ;11(3):272-275

Dept. of Pathology, JN Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

Chondromyxoid fibroma (CMF) is a rare benign cartilaginous tumor with a predilection for the bones of lower extremities and about one fourth of the tumors involve the foot. Radiologically, an eccentric lytic lesion with well-defined margins is seen in the metaphysis of the bone. We hereby, report an 18 yr old young male who presented to Orthopedic Outpatient Department, JN Medical College, Aligarh Muslim University, India diagnosed with giant cell tumor of the third metatarsal bone of right foot on radiography but on fine needle aspiration cytology (FNAC) the diagnosis of CMF was made. Read More

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January 2016
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