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    100 results match your criteria Chondrodermatitis Nodularis Helicis

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    Observational study of chondrodermatitis nodularis helicis treated with methyl aminolevulinate photodynamic therapy.
    J Am Acad Dermatol 2017 Feb 16. Epub 2017 Feb 16.
    Unit of Dermatology, San Jorge Hospital, Huesca, Spain.
    Background: Therapies used to treat chondrodermatitis nodularis helicis (CNH), such as surgical excision, pressure relief, or topical steroids report varying degrees of success.

    Objective: We evaluated the response and safety of methyl aminolevulinate (MAL) photodynamic therapy (PDT) in CNH.

    Methods: This retrospective, observational study performed at the University Hospital Ramon y Cajal (Madrid, Spain) and Hospital San Jorge (Huesca, Spain) included all patients diagnosed with CNH and treated with MAL-PDT from 2008 to 2015. Read More

    Chondrodermatitis nodularis helicis: A review of current therapies.
    Dermatol Ther 2017 Jan 9;30(1). Epub 2016 Oct 9.
    Texas A&M Health Science Center College of Medicine, Temple, Texas, USA.
    Chondrodermatitis nodularis helicis (CNH) is characterized by a tender nodule located on the helix or antihelix. Age groups impacted by CNH vary from study to study, but the majority of studies report an average age range from 50 to 80 years. Various treatment options have been described in the literature, including surgical techniques, laser therapy, curettage, topical and intralesional corticosteroids, and pressure relieving techniques. Read More

    Management of Chondrodermatitis Nodularis Helicis: A Systematic Review and Treatment Algorithm.
    Dermatol Surg 2016 Oct;42(10):1125-34
    *Department of Dermatology, Hotel Dieu de France Hospital; †Saint Joseph University, Faculty of Medicine, and Departments of Plastic and Reconstructive Surgery, ‡Dermatology, and §Ophtalmology, Hotel Dieu de France Hospital, Achrafieh, Lebanon; ‖Saint Joseph University, Factulty of Medicine, and Hotel Dieu de France Hospital, Achrafieh, Lebanon.
    Background: Chondrodermatitis nodularis helicis (CNH) is an idiopathic benign inflammatory painful condition of the ear. Still, to date, no study has yet evaluated nor compared treatments regarding their safety and efficacy.

    Objective: The objective of this study is to review all available treatment modalities of CNH that were described in the literature, compare their efficacy and propose a treatment algorithm. Read More

    Therapeutic Options of Chondrodermatitis Nodularis Helicis.
    Plast Surg Int 2016 27;2016:4340168. Epub 2016 Jan 27.
    Department of Plastic Surgery and Breast Surgery, Roskilde Hospital, 4000 Roskilde, Denmark.
    Chondrodermatitis Nodularis Helicis is a benign inflammatory process affecting the skin and cartilage of the ear. It typically presents as a painful nodule surrounded by an area of erythema and often prevents the patient from sleeping on the affected side. Many treatments have been described in the literature, but the condition is prone to recurrence. Read More

    The Usefulness of 0.2% Topical Nitroglycerin for Chondrodermatitis Nodularis Helicis.
    Actas Dermosifiliogr 2015 Sep 20;106(7):555-61. Epub 2015 May 20.
    Servicio de Dermatología, Hospital Universitario 12 de Octubre, Madrid, España.
    Background And Objective: Chondrodermatitis nodularis helicis (CNH) is a painful idiopathic degenerative condition involving the skin and cartilage of the helix or antihelix of the ear. Topical nitroglycerin 2% is a relatively recent treatment option for CNH that has produced good results, although with adverse effects (17% of cases). The use of a lower concentration would probably achieve similar results with fewer adverse effects. Read More

    Chondrodermatitis nodularis chronica helicis in a patient with systemic sclerosis associated with primary biliary cirrhosis (Reynolds syndrome): A case report.
    Eur J Rheumatol 2014 Dec 1;1(4):161-163. Epub 2014 Dec 1.
    Department of Rheumatology, University Hospital Ramón y Cajal, Madrid, Spain.
    Chondrodermatitis nodularis chronica helicis is a rare non-neoplastic inflammatory and degenerative process of the external ear, characterized by necrobiotic changes in the dermis that extend down to the perichondrium. This condition has been occasionally reported in patients with limited cutaneous systemic sclerosis but not in those with concomitant primary biliary cirrhosis; this association is known as Reynolds syndrome. We report a 70-year-old woman diagnosed with primary biliary cirrhosis at age 47 and with limited cutaneous systemic sclerosis at age 54 who developed a painful ulcerated nodule on the helical rim of the left ear shortly after the last diagnosis. Read More

    Nitroglycerin patch for the treatment of chondrodermatitis nodularis helicis: a new therapeutic option.
    Dermatol Ther 2014 Sep-Oct;27(5):278-80. Epub 2014 Jun 9.
    Dermatology and Venereology Department, Virgen de Las Nieves Hospital, Granada, Spain.
    Chondrodermatitis nodularis helicis (CNH) is an inflammatory process that affects the skin and cartilage of the ear. At present, there are many treatment options, although they are not always effective. Based on previous studies where nitroglycerin 2% gel was used, we propose the use of nitroglycerin patches. Read More

    [Chondrodermatitis nodularis chronica helicis: a descriptive study of 99 patients].
    Ann Dermatol Venereol 2013 Nov 22;140(11):687-92. Epub 2013 Oct 22.
    Clinique dermatologique de Strasbourg, hôpital civil de Strasbourg, 1, place de l'Hôpital, 97091 Strasbourg cedex, France. Electronic address:
    Background: Painful nodule of the ear was described at the start of the 20th century as a form of chronic chondrodermatitis nodularis helicis (CNH). It comprises a painful erythematous papule or nodule appearing on the ear and adhering to cartilage, and which may or may not have a central scab. The aim of this study was to describe the clinical characteristics of CNH as well as the population currently affected by such lesions, and to identify predisposing factors. Read More

    Gouty tophi on the ear: a review.
    Cutis 2013 Oct;92(4):190-2
    Midlands Clinic, 705 N Sioux Point Rd, Dakota Dunes, SD 57049, USA.
    Although the classic location of gouty tophi is the great toe (podagra), gouty tophi of the ear also is common and is worth including in the differential diagnosis in patients presenting with ear lesions. Other entities presenting as papules or nodules on the ear include chondrodermatitis nodularis helicis (CNH), actinic keratosis, basal cell carcinoma, squamous cell carcinoma, verruca vulgaris, amyloids, rheumatoid nodules, and elastotic nodules. If tophaceous gout is suspected, alcohol fixation of the biopsy specimen is preferable, as it enables visualization of characteristic needle-shaped urate crystals. Read More

    Chondrodermatitis nodularis chronica helicis excision and reconstruction.
    J Laryngol Otol 2013 Jan 7;127(1):63-4. Epub 2012 Dec 7.
    Department of Otolaryngology, Head and Neck Surgery, Southern General Hospital, Glasgow, Scotland, UK.
    Background: Chondrodermatitis nodularis chronica helicis is a common benign condition of the pinna. It presents as a painful, well demarcated nodule on the pinna that may be associated with surrounding erythema or an overlying crust.

    Methods: This paper describes techniques for the excision of chondrodermatitis nodularis chronica helicis on both the helix and anti-helix, and reconstruction of the defect. Read More

    Accessory tragus: a possible sign of Goldenhar syndrome.
    Cutis 2011 Aug;88(2):62-4
    New Jersey Medical School, 185 South Orange Ave, Newark, NJ 07103, USA.
    The accessory tragus is a relatively common benign congenital anomaly. The tragus is a cartilaginous projection that normally occurs anterior to the external auditory meatus. Although aberrancy of the tragus may occur in isolation and is exclusively derived from the first branchial arch, it may occasionally signal a defect in the first or second branchial arches. Read More

    Topical nitroglycerin: a promising treatment option for chondrodermatitis nodularis helicis.
    J Am Acad Dermatol 2011 Sep 6;65(3):531-6. Epub 2011 May 6.
    Division of Dermatology, Scott and White Memorial Hospital and Clinic and Texas A&M Health Science Center College of Medicine, Temple, TX 76501, USA.
    Background: Chondrodermatitis nodularis helicis (CNH) is a painful nodule that often interferes with sleep and occurs on the helix or antihelix of the ear in older patients. Although several case reports describe a variety of seemingly effective surgical and conservative treatment options, well-studied treatment modalities have varying efficacy rates and can often demonstrate disappointing results.

    Objectives: The purpose of this study was to evaluate the efficacy of 2% topical nitroglycerin for the treatment of CNH. Read More

    Clinical appearance, differential diagnoses and therapeutical options of chondrodermatitis nodularis chronica helicis Winkler.
    J Dtsch Dermatol Ges 2011 Apr 31;9(4):287-91. Epub 2011 Jan 31.
    Department of Dermatology, Bremerhaven Reinkenheide Hospital, Bremerhaven, Germany.
    The article on chondrodermatitis nodularis chronica helicis summarizes various clinical pictures and differential diagnoses of this entity. This lesion is usually characterized by a solid or cystic nodule but ulcerations or crusts may also occur. The most common differential diagnoses include benign or malignant tumours, which are often confused with chondrodermatitis nodularis chronica helicis. Read More

    Chondrodermatitis nodularis chronica helicis and photodynamic therapy: a new therapeutic option?
    Dermatol Ther 2011 Jan-Feb;24(1):144-7
    Department of Dermatology, University of Siena A.O.U.S., Siena, Italy.
    Chondrodermatitis nodularis chronica helicis (CNCH) is a fairly frequent disorder of unknown etiology. Although the elective therapy is surgery, local application of topical steroids, antibiotic ointments, intralesional injection of collagen, cryotherapy, curettage followed by diathermy, and CO(2) laser treatment have also been proposed. The aim of the study was to test the utility of photodynamic therapy (PDT) for CNCH. Read More

    Chondrodermatitis nodularis chronica helicis - a conservative therapeutic approach by decompression.
    J Dtsch Dermatol Ges 2011 Apr 23;9(4):292-6. Epub 2010 Nov 23.
    Department of Dermatology and Venereology, Medical University of Innsbruck, Austria.
    Background: Chondrodermatitis nodularis chronica helicis is a rather common condition which substantially affects quality of life causing pain and sleeping disturbances. Surgical treatment is connected with a tendency to recurrence. Mechanical pressure is probably the main etiological factor. Read More

    Advances in the understanding of chondrodermatitis nodularis chronica helices: the perichondrial vasculitis theory.
    Clin Otolaryngol 2009 Apr;34(2):147-50
    Head and Neck Department, University College London Hospital, London, UK.
    Objectives: Chondrodermatitis nodularis chronica helicis (CNCH) usually presents as a painful nodule affecting the pinna. The aetiology of the disease is unknown. Several theories have been suggested. Read More

    Chondrodermatitis nodularis chronica helicis in monozygotic twins.
    Clin Exp Dermatol 2009 Apr 29;34(3):358-9. Epub 2008 Oct 29.
    Department of Dermatology, University of California, San Francisco, CA 94143-0989, USA.
    Chondrodermatitis nodularis chronica helicis (CNCH) is a benign inflammatory nodule of the helix. Patients report severe tenderness upon pressure. Commonly seen in middle-aged men, there are no reports of this disease in twins. Read More

    The use of C3d and C4d immunohistochemistry on formalin-fixed tissue as a diagnostic adjunct in the assessment of inflammatory skin disease.
    J Am Acad Dermatol 2008 Nov;59(5):822-33
    Department of Pathology and Laboratory Medicine, Weill Medical College of Cornell University, New York, New York 10065, USA.
    Background: Direct immunofluorescent (DIF) testing defines an important diagnostic adjunct in the classification of various inflammatory skin conditions; it requires fresh tissue, a laboratory equipped to perform the procedure, and a pathologist skilled in its interpretation. Although advances have been made in the development of antibodies that can be applied to paraffin-embedded tissue, there has been no reported success on the application of paraffin tissue-based immunohistochemistry as a potential substitute for DIF testing on skin biopsy material.

    Objective: We applied C3d and C4d immunohistochemistry on paraffin-embedded, formalin-fixed tissue to define a potential application of these two antibodies as a diagnostic adjunct in the evaluation of various inflammatory skin diseases. Read More

    The punch and graft technique: a novel method of surgical treatment for chondrodermatitis nodularis helicis.
    Br J Dermatol 2007 Oct 2;157(4):744-7. Epub 2007 Aug 2.
    Department of Dermatology, Sunderland Royal Hospital, Sunderland, U.K.
    Background: Chondrodermatitis nodularis helicis (CDNH) is a painful inflammatory condition affecting the helix of the ear. Several surgical treatments are described in the literature, with different cure rates and cosmetic outcomes.

    Objectives: To determine the cure rate of a novel method of surgical treatment, the 'punch and graft' technique, for CDNH and to compare this with reported techniques. Read More

    Management of chondrodermatitis nodularis chronica helicis using a 'doughnut pillow'.
    J Laryngol Otol 2007 Nov 24;121(11):1096-8. Epub 2007 May 24.
    Department of ENT, Wrexham Maelor Hospital, Wrexham, UK.
    Unlabelled: Chondrodermatitis nodularis chronica helicis is a well-recognised painful condition of the pinna. There have been several modes of treatment described for this condition. Although the most common mode of treatment is surgery,1,2 several conservative approaches have also been tried. Read More

    Pediatric chondrodermatitis nodularis helicis.
    J Craniofac Surg 2007 Jan;18(1):228-31
    Department of Plastic Surgery, University of Virginia Health System, Charlottesville 22908-0376, USA.
    Chondrodermatitis nodularis helicis (CNH) is a rare condition of the pinna affecting mainly adults. A pediatric case of this condition is presented in the current report, and the literature of pediatric CNH is reviewed. Read More

    Neural hyperplasia in chondrodermatitis nodularis chronica helicis.
    J Am Acad Dermatol 2006 Nov;55(5):844-8
    Cutaneous Histopathology Laboratory, Dermatology Clinic of the University Hospitals, Strasbourg, France.
    Background: Chondrodermatitis nodularis chronica helicis (CNCH) is a common condition characterized by tender nodules of the helix, of uncertain mechanism. The pain is not explained by current physiopathological hypotheses.

    Objective: We sought to investigate possible nerve hyperplasia in CNCH. Read More

    Chondrodermatitis nodularis helicis as a marker of internal disease [corrected] associated with microvascular injury.
    J Cutan Pathol 2005 May;32(5):329-33
    Department of Pathology, The Ohio State University, Columbus, OH, USA.
    Chondrodermatitis nodularis helicis (CNH) is held to be an idiopathic degenerative process involving the upper dermis of the auricular rim. Chondrodermatitis typically occurs in elderly men where associations with underlying trauma and sun exposure have been postulated as potential inciting triggers. Its association as a marker of systemic disease is not well established. Read More

    Effective treatment of chondrodermatitis nodularis chronica helicis using a conservative approach.
    Br J Dermatol 2004 May;150(5):892-4
    Department of Plastic and Reconstructive Surgery, Norfolk and Norwich University Hospital NHS Trust, Norwich NR4 7UY, UK.
    Background: Chondrodermatitis nodularis chronica helicis (CNCH) is usually treated by surgical excision, but is prone to recurrence.

    Objectives: To examine whether CNCH could be treated nonsurgically using a home-made, pressure-relieving prosthesis.

    Methods: A retrospective comparison was made of the outcome in 41 subjects treated surgically and 15 treated nonsurgically between 1999 and 2001. Read More

    Juvenile chondrodermatitis nodularis helicis: a case report and literature review.
    Pediatr Dermatol 2003 Nov-Dec;20(6):488-90
    Department of Pathology, Tulane University Health Sciences Center, New Orleans, Louisiana 70112-2699, USA.
    Chondrodermatitis nodularis helicis (CNH) is a disorder that affects adults. Only one case of juvenile CNH has been reported, in an 8-year-old child who suffered from dermatomyositis. We report another child with juvenile CNH who was not afflicted with dermatomyositis or other systemic disorders. Read More

    Bilateral chondrodermatitis nodularis chronica helicis on the free border of the helix in a woman.
    J Am Acad Dermatol 2003 Oct;49(4):720-2
    Department of Dermatology, Friedrich-Schiller-University, Jena, Germany.
    Chondrodermatitis nodularis chronica helicis is characterized by the presence of small, intensely painful nodules on the free border of the helix of the ear with unknown origin. The lesion is typically localized unilaterally on the right ear. Pressure and trauma may play a role. Read More

    Connective tissue tumors.
    Recent Results Cancer Res 2002 ;160:343-50
    Department of Dermatology, University of Innsbruck, Austria.
    Connective tissue consists of collagen, elastic fibers and ground substances produced by fibrocytes. These cells are usually spindle-shaped with slender nuclei and bipolar cytoplasmic extensions. Apart from labeling for vimentin and variable reactivity for factor XIIIa and CD34, fibrocytes are immunonegative. Read More

    Chondrodermatitis nodularis chronica helicis.
    Arch Fam Med 1999 Sep-Oct;8(5):445-7
    Department of Family Medicine, Saginaw Cooperative Hospitals, Mich., USA.
    Chondrodermatitis nodularis chronica helicis is a painful nodule of the external ear. These uncommon lesions are most often encountered on the helix in white men older than 40 years, although they also rarely occur on the antihelix in women. The lesions frequently present with exquisite tenderness that interferes with sleep. Read More

    Auricular ossification.
    Australas J Dermatol 1998 Nov;39(4):268-70
    Department of Dermatology, Royal Melbourne Hospital, Parkville, Victoria, Australia.
    A patient with extensive bilateral auricular ossification presented with chondrodermatitis nodularis helicis on one side. The condition was otherwise asymptomatic. Ossification was detected on radiological and histological examination. Read More

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