2,290 results match your criteria Chondrocalcinosis


Severe hemochromatosis arthropathy in the absence of iron overload.

Hepatology 2018 Dec 18. Epub 2018 Dec 18.

London Health Sciences Centre University Hospital, 339 Windermere Rd, London, Ontario, Canada.

An 18 year old man presented with bilateral knee pains. He had first developed symptoms at age 15 in 1991. Physical examination in 1995 by a senior rheumatology consultant showed patellofemoral crepitus and pain on movement of the patellae over the femur with slight loss of flexion. Read More

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http://doi.wiley.com/10.1002/hep.30469
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http://dx.doi.org/10.1002/hep.30469DOI Listing
December 2018
4 Reads

Spinal involvement with calcium pyrophosphate deposition disease in an academic rheumatology center: A series of 37 patients.

Semin Arthritis Rheum 2018 Oct 14. Epub 2018 Oct 14.

Université Paris Diderot France, France; Department of Rheumatology, Hôpital Lariboisière, Assistance Publique des Hôpitaux de Paris, 75010 Paris, France; INSERM U1132, Hôpital Lariboisière, Université Paris Diderot, France. Electronic address:

Background: Calcium pyrophosphate dihydrate deposition disease (CPPD) has been reported to involve the spine, but few systematic studies have been published.

Objective: To further characterize the spinal involvement with CPPD by a review of CPPD patients hospitalized in a rheumatology department.

Methods: We retrospectively reviewed data for patients consecutively admitted with a diagnosis of CPPD in the rheumatology department of Lariboisière hospital in Paris, France over 5 years by using a standardized protocol and electronic case report forms. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00490172183043
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http://dx.doi.org/10.1016/j.semarthrit.2018.10.009DOI Listing
October 2018
6 Reads

[A muscular calcium pyrophosphate deposition pseudo-abscess: An atypical localization of chondrocalcinosis].

Rev Med Interne 2018 Oct 19. Epub 2018 Oct 19.

Service de médecine interne, hôpital Avicenne, AP-HP, 93000 Bobigny, France.

Introduction: Chondrocalcinosis results from calcium pyrophosphate crystals deposition in the joints. We report an exceptional case of aseptic psoas abscess with a deposition of calcium pyrophosphate crystals.

Case Report: A 92-year-old man presented to our department for an acute onset of inflammatory pain in the left hip. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02488663183070
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http://dx.doi.org/10.1016/j.revmed.2018.09.006DOI Listing
October 2018
7 Reads

Synovial Chondromatosis and Calcium Pyrophosphate Deposition of the Temporomandibular Joint: Challenging Diagnosis.

J Craniofac Surg 2018 Nov;29(8):e792-e794

Department of Maxillofacial Surgery.

Background: The association between the synovial chondromatosis (SC) and the calcium pyrophosphate deposition (pseudogotta) in temporomandibular joint (TMJ) is very rare and has been described just 1 patient in the literature.

Clinical Presentation: A 64-year-old woman was referred to Dipartimento di Scienze Odontostomatologiche e Maxillo-Facciali, Sapienza Università di Roma after complaining about right temporomandibular pain, limitation in mandibular movements, and tumefaction in the right preauricular region. The patient was hospitalized for the surgery. Read More

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http://dx.doi.org/10.1097/SCS.0000000000004830DOI Listing
November 2018
10 Reads

Subclinical crystal arthropathy: a silent contributor to inflammation and functional disability in knees with osteoarthritis-an ultrasound study.

J Med Ultrason (2001) 2018 Oct 16. Epub 2018 Oct 16.

Rheumatology Department, Università Politecnica delle Marche, "Carlo Urbani" Hospital, Iesi, Ancona, Italy.

Purpose: This study aimed at investigating the prevalence of crystal deposits with knee osteoarthritis (OA) by ultrasonography and measure the inflammatory burden associated with crystal deposits in OA using WOMAC score.

Methods: Adult patients with primary knee OA diagnosed according to the American College of Rheumatology criteria were included. Participants were subjected to history taking, clinical examination, knee US, and plain radiography. Read More

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http://dx.doi.org/10.1007/s10396-018-0912-zDOI Listing
October 2018
21 Reads
0.740 Impact Factor

Ultrasonography, an operator-dependent modality versus dual-energy computed tomography (DECT) in the detection of chondrocalcinosis: with regard to Tanikawa et al.'s study.

Authors:
Angel Checa

J Orthop Surg Res 2018 Oct 16;13(1):255. Epub 2018 Oct 16.

Lourdes Medical Center Burlington County, Willingboro, NJ, 08046, USA.

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http://dx.doi.org/10.1186/s13018-018-0953-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6192358PMC
October 2018
1 Read

Age-Related Prevalence of Periodontoid Calcification and Its Associations with Acute Cervical Pain.

Asian Spine J 2018 Dec 16;12(6):1117-1122. Epub 2018 Oct 16.

Department of Orthopedic Surgery, Akita University Graduate School of Medicine, Akita, Japan.

Study Design: Prospective study.

Purpose: To assess the prevalence of periodontoid calcification and its associations with acute cervical pain.

Overview Of Literature: Calcium pyrophosphate dihydrate (CPPD) deposition disease is a common rheumatological disorder that occurs especially in elderly patients. Read More

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http://dx.doi.org/10.31616/asj.2018.12.6.1117DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284135PMC
December 2018
1 Read

Reverse Total Shoulder Arthroplasty: Indications and Techniques Across the World.

Am J Orthop (Belle Mead NJ) 2018 Sep;47(9)

Department of Orthopedic Surgery, Academic Medical Center, Amsterdam, The Netherlands.

Reverse total shoulder arthroplasty (RTSA) is a common treatment for rotator cuff tear arthropathy. We performed a systematic review of all the RTSA literature to answer if we are treating the same patients with RTSA, across the world. A systematic review was registered with PROSPERO, the international prospective register of systematic reviews, and performed with Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines using 3 publicly available free databases. Read More

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http://dx.doi.org/10.12788/ajo.2018.0079DOI Listing
September 2018
15 Reads

Severe calcium pyrophosphate dihydrate deposition disease of the metacarpophalangeal joints.

BMJ Case Rep 2018 Sep 28;2018. Epub 2018 Sep 28.

Medicine/Rheumatology, University of Kentucky, Lexington, Kentucky, USA.

We report a case of calcium pyrophosphate deposition disease (CPPD) with an unusual presentation of severe chondrocalcinosis with atypical large burden deposited in the metacarpophalangeal joints as well as more typical deposition in wrists and knees as demonstrated on plain radiographs. A 77-year-old African-American woman 1-year status post parathyroidectomy for hyperparathyroidism initially presented to the rheumatology clinic to treat suspected rheumatoid arthritis given her pattern of joint involvement but was found to have CPPD. The patient's history is notable for end-stage renal disease which complicates medical management. Read More

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http://dx.doi.org/10.1136/bcr-2018-226132DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6169684PMC
September 2018
8 Reads

Localised foot and ankle amyloid deposition.

Pathol Res Pract 2018 Oct 27;214(10):1661-1666. Epub 2018 Aug 27.

Department of Histopathology, NDORMS, University of Oxford, Nuffield Orthopaedic Centre, Oxford, OX3 7HE, UK. Electronic address:

Background: Localised (transthyretin-associated) amyloid is commonly seen in articular/periarticular tissues of elderly individuals. Whether age-associated, amyloid deposition occurs in foot and ankle (F&A) tissues has not previously been investigated. In this study we assessed the nature and frequency of F&A amyloid deposition and determined whether it is associated with age and/or specific articular/periarticular F&A lesions. Read More

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http://dx.doi.org/10.1016/j.prp.2018.08.027DOI Listing
October 2018
2 Reads

Clinical features and risk of recurrence of acute calcium pyrophosphate crystal arthritis.

Clin Exp Rheumatol 2018 Jul 19. Epub 2018 Jul 19.

Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea.

Objectives: It is unclear whether attack recurrence rates are similar between acute calcium pyrophosphate (CPP) crystal arthritis and gout. This study compared the clinical features and recurrence rates of both conditions.

Methods: In this retrospective study, we reviewed 106 patients with acute CPP crystal arthritis (based on the presence of CPP crystals and/or chondrocalcinosis) and 173 patients with gout (based on the presence of monosodium urate crystals). Read More

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July 2018
4 Reads

[Update on Gout and Calcium pyrophosphate deposition (CPPD)].

Dtsch Med Wochenschr 2018 Aug 7;143(16):1157-1166. Epub 2018 Aug 7.

The metabolic diseases gout and calciumpyrophosphate deposition (CPPD) (formerly: chondrocalcinosis/pseudogout) are crystal arthropathies which are caused by crystals in synovial fluid and in the case of gout also in periarticular structures. Today, in particular gout is considered as an auto-inflammatory process since phagocytosis of monosodium urate crystals by monocytes/macrophages results in the activation of the innate immune system by activation of the NRLP3-Inflammasome and consecutive secretion of the key cytokine interleukin-1ß and other pro-inflammatory cytokines. The prevalence of both crystal arthropathies rises with increasing age of patients. Read More

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http://dx.doi.org/10.1055/a-0504-5684DOI Listing
August 2018
2 Reads

Pain after stroke: A review.

Rev Neurol (Paris) 2018 Dec 24;174(10):671-674. Epub 2018 Jul 24.

Unité de soins intensifs neuro-vasculaires et réseau bourgogne-AVC, CHU de Dijon Bourgogne, 14, rue Paul-Gaffarel, 21079 Dijon cedex, France.

Pain after stroke (PAS) is a common clinical problem that is both underdiagnosed and undertreated. Yet, it induces depression and cognitive troubles, and impairs quality of life. To provide tools for practitioners, this report describes the most common PAS syndromes, including central post-stroke pain, spasticity and contractures, shoulder pain and complex regional pain syndromes, as well as headache and chondrocalcinosis, along with their risk factors, their prevention and their specific treatments. Read More

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http://dx.doi.org/10.1016/j.neurol.2017.11.011DOI Listing
December 2018
2 Reads

Unicompartmental knee arthroplasty: Current indications, technical issues and results.

EFORT Open Rev 2018 06 6;3(6):363-373. Epub 2018 Jun 6.

Department of Orthopaedic Surgery, La Paz University Hospital - IdiPaz, Spain.

An age younger than 60 years, a body weight of 180 lb (82 kg) or more, performing heavy work, having chondrocalcinosis and having exposed bone in the patellofemoral (PF) joint are not contraindications for unicompartmental knee arthroplasty (UKA).Severe wear of the lateral facet of the PF joint with bone loss and grooving is a contraindication for UKA.Medial UKA should only be performed in cases of severe osteoarthritis (OA) as shown in pre-operative X-rays, with medial bone-on-bone contact and a medial/lateral ratio of < 20%. Read More

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http://dx.doi.org/10.1302/2058-5241.3.170048DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026888PMC
June 2018
4 Reads

Incidence of knee chondrocalcinosis and its risk factors in a community-based cohort.

Int J Rheum Dis 2018 Jul;21(7):1391-1397

Department of Rheumatology, Hanyang University Hospital for Rheumatic Diseases, Seoul, Korea.

Aim: Chondrocalcinosis results from deposition of calcium pyrophosphate dihydrate in articular cartilage. It is a relatively common radiographic finding of the joints, especially the knee. This study investigated the incidence and the risk factors for the development of knee chondrocalcinosis in the general population. Read More

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http://dx.doi.org/10.1111/1756-185X.13317DOI Listing
July 2018
5 Reads

Acute locked superior shoulder dislocation in a patient with cuff tear arthropathy.

BMJ Case Rep 2018 Jun 20;2018. Epub 2018 Jun 20.

Center for Musculoskeletal Surgery, Charite Universitatsmedizin Berlin Campus Virchow-Klinikum, Berlin, Germany.

In the field of traumatic shoulder dislocations, this report of a 61-year-old female patient discusses the case of an acute locked superior shoulder dislocation in conjunction with a chronic rotator cuff arthropathy resulting from a low-energy fall on the outstretched and abducted arm. Radiological assessment revealed a complex combination of associated bony injuries including a fracture of the upper part of the glenoid and an impaction fracture of the inferior articular surface of the humeral head. Closed reduction and immobilisation were not successful in obtaining joint stability. Read More

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http://dx.doi.org/10.1136/bcr-2018-225237DOI Listing
June 2018
10 Reads

SMOC2 inhibits calcification of osteoprogenitor and endothelial cells.

PLoS One 2018 13;13(6):e0198104. Epub 2018 Jun 13.

Laboratory of Tissue Homeostasis and Disease, Skeletal Biology and Engineering Research Center, Department of Development and Regeneration, KU Leuven, Leuven, Belgium.

Tissue calcification is an important physiological process required for the normal structure and function of bone. However, ectopic or excessive calcification contributes to diseases such as chondrocalcinosis, to calcium deposits in the skin or to vascular calcification. SMOC2 is a member of the BM-40/osteonectin family of calcium-binding secreted matricellular proteins. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0198104PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5999237PMC
January 2019
5 Reads

Emergent nanotherapies in microcrystal-induced arthritis.

Int Immunopharmacol 2018 Aug 8;61:197-203. Epub 2018 Jun 8.

Laboratorio de Líquido Sinovial, Instituto Nacional de Rehabilitación "Luis Guillermo Ibarra-Ibarra (INR-LGII), Calz. México-Xochimilco No. 289, Col. Arenal de Guadalupe, Delegación Tlalpan, C.P. 14389 Ciudad de México, Mexico.

The anti-inflammatory and immunomodulatory effects of nanoparticles in several chronic diseases have been extensively researched. The aim of this review is to examine how nanoparticles modulate the inflammatory pathways that characterize the most prevalent forms of microcrystal-induced arthritis, including gout, pseudogout, and BCP-induced arthritis. The nanoparticles of chitosan-coated calcium phosphate, uricase, aceclofenac, and gold have been investigated in crystal-inducedarthritis. Read More

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http://dx.doi.org/10.1016/j.intimp.2018.06.007DOI Listing
August 2018
19 Reads

Calcification of the acetabular labrum of the hip: prevalence in the general population and relation to hip articular cartilage and fibrocartilage degeneration.

Arthritis Res Ther 2018 05 30;20(1):104. Epub 2018 May 30.

Department of Orthopaedics, University Medical Center Hamburg-Eppendorf, Martinistraße 52, 20246, Hamburg, Germany.

Background: Meniscal calcification is considered to play a relevant role in the pathogenesis of osteoarthritis of the knee. Little is known about the biology of acetabular labral disease and its importance in hip pathology. Here, we analyze for the first time the calcification of the acetabular labrum of the hip (ALH) and its relation to hip cartilage degeneration. Read More

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http://dx.doi.org/10.1186/s13075-018-1595-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5977492PMC
May 2018
6 Reads

Cartilage diseases.

Matrix Biol 2018 10 24;71-72:51-69. Epub 2018 May 24.

Department of Biological Engineering, MIT, Cambridge, MA 02139, USA; Department of Mechanical Engineering, MIT, Cambridge, MA 02139, USA; Department of Electrical Engineering and Computer Science, MIT, Cambridge, MA 02139, USA. Electronic address:

Hyaline cartilages, fibrocartilages and elastic cartilages play multiple roles in the human body including bearing loads in articular joints and intervertebral discs, providing joint lubrication, forming the external ears and nose, supporting the trachea, and forming the long bones during development and growth. The structure and organization of cartilage's extracellular matrix (ECM) are the primary determinants of normal function. Most diseases involving cartilage lead to dramatic changes in the ECM which can govern disease progression (e. Read More

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http://dx.doi.org/10.1016/j.matbio.2018.05.005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6146013PMC
October 2018
24 Reads

Cartilage calcification of the ankle joint is associated with osteoarthritis in the general population.

BMC Musculoskelet Disord 2018 May 24;19(1):169. Epub 2018 May 24.

Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University Medical Center Göttingen, Robert-Koch-Straße 40, 37075, Göttingen, Germany.

Background: Cartilage calcification (CC) is associated with osteoarthritis (OA) in weight-bearing joints, such as the hip and the knee. However, little is known about the impact of CC and degeneration on other weight-bearing joints, especially as it relates to the occurrence of OA in the ankles. The goal of this study is to analyse the prevalence of ankle joint cartilage calcification (AJ CC) and to determine its correlation with factors such as histological OA grade, age and BMI in the general population. Read More

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https://bmcmusculoskeletdisord.biomedcentral.com/articles/10
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http://dx.doi.org/10.1186/s12891-018-2094-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5968601PMC
May 2018
7 Reads

Risk and risk factors for revision after primary reverse shoulder arthroplasty for cuff tear arthropathy and osteoarthritis: a Nordic Arthroplasty Register Association study.

J Shoulder Elbow Surg 2018 Sep 18;27(9):1596-1601. Epub 2018 May 18.

Department of Orthopedics and Traumatology, Turku University Hospital, Turku, Finland.

Background: Reverse shoulder arthroplasty (RSA) has gained increasing popularity in the treatment of rotator cuff tear arthropathy (CTA). The purpose of this study was to evaluate the survival of RSA and the risk factors for revision following RSA.

Methods: RSA patients with CTA or osteoarthritis were identified from the Nordic Arthroplasty Register Association registry data (2004-2013). Read More

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http://dx.doi.org/10.1016/j.jse.2018.02.060DOI Listing
September 2018
2 Reads

Diagnosis and Treatment of Gout and Pseudogout for Everyday Practice.

Prim Care 2018 Jun;45(2):213-236

San Antonio Uniformed Services Health Consortium, Department of Rheumatology, 3851 Roger Brooke Drive, San Antonio, TX 78234, USA.

Gout and pseudogout are crystalline arthropathies commonly seen in primary care. It is important to understand their pathophysiology to facilitate recognition and appropriate treatment. Prompt gouty arthritis treatment relieves short-term suffering. Read More

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http://dx.doi.org/10.1016/j.pop.2018.02.004DOI Listing
June 2018
6 Reads

The "tipping point" for 931 elective shoulder arthroplasties.

J Shoulder Elbow Surg 2018 Sep 7;27(9):1614-1621. Epub 2018 May 7.

Department of Orthopaedics and Sports Medicine, University of Washington, Seattle, WA, USA. Electronic address:

Background: A patient with arthritis usually experiences the progression of symptoms over time. At some stage, the patient may decide that the symptoms have reached a level of severity that leads him or her to elect to proceed with joint replacement; we refer to this degree of symptom severity as the "tipping point." Our goal was to study the factors that influenced the tipping point for patients undergoing elective shoulder arthroplasty. Read More

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http://dx.doi.org/10.1016/j.jse.2018.03.008DOI Listing
September 2018
1 Read

Long-term clinical and radiographic outcome of rotator cuff repair with a synthetic interposition graft: a consecutive case series with 17 to 20 years of follow-up.

J Shoulder Elbow Surg 2018 Sep 3;27(9):1622-1628. Epub 2018 May 3.

Department of Clinical and Experimental Medicine, Faculty of Health Sciences, Linköping University, Linköping, Sweden; Department of Orthopedics, Linköping University Hospital, Linköping, Sweden.

Background: Treatment options for irreparable cuff tears include synthetic interposition grafts, but whether such grafts can maintain acceptable shoulder function and prevent cuff tear arthropathy in the long-term is unknown.

Method: This was a retrospective case series of 13 consecutive patients treated with a synthetic interposition graft made of Dacron (DuPont, Wilmington, DE, USA). Patients were examined with bilateral ultrasonography, bilateral x-ray imaging, Constant-Murley score, and Western Ontario Rotator Cuff score. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10582746183022
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http://dx.doi.org/10.1016/j.jse.2018.03.011DOI Listing
September 2018
2 Reads

Radiological features of crystal-induced arthropathy associated with hereditary hemochromatosis with homozygous C282Y mutation.

Reumatol Clin 2018 May 3. Epub 2018 May 3.

Servicio de Reumatología, Hospital Universitario Nuestra Señora de Candelaria, Santa Cruz de Tenerife, Tenerife, España. Electronic address:

I present a clinical case of a 64-year-old male patient with hemochromatosis (homozygous C282Y) and crystal induced arthropathy showing the most common radiological features found in this metabolic disorder and the differences that may exist when compared to other primary degenerative processes or other inflammatory pathologies. Read More

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http://dx.doi.org/10.1016/j.reuma.2018.01.012DOI Listing
May 2018
5 Reads

Clinical and ultrasound findings in patients with calcium pyrophosphate dihydrate deposition disease.

Med Ultrason 2018 May;20(2):159-163

Department Of Rheumatology,Iuliu Haţieganu University of Medicine and Pharmacy Cluj-Napoca, Cluj-Napoca, Romania.

Aim: To evaluate the presence and distribution of calcium pyrophosphate (CPP) deposits in joints commonly affected by CPP deposition (CPPD) disease (acromio-clavicular, gleno-humeral, wrists, hips, knees, ankles, and symphysis pubis joints) using ultrasound (US).

Material And Methods: Thirty consecutive patients fulfilling McCarty diagnostic criteria for CPPD were consecutively enrolled in the study. The data registered using the US included the affected joints, the calcification site, and the pattern of calcification (thin hyperechoic bands, parallel to the surface of the hyaline cartilage, hyperechoic spots, and hyperechoic nodular or oval deposits). Read More

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http://dx.doi.org/10.11152/mu-1193DOI Listing
May 2018
4 Reads

Coexisting Gout and Chondrocalcinosis on Hand Radiograph.

J Rheumatol 2018 May;45(5):723-724

Department of Rheumatology, University Teaching Hospital, Besançon, France. Ethics approval for this case report was not required in accordance with the policy of the authors' institution.

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http://dx.doi.org/10.3899/jrheum.171154DOI Listing
May 2018
16 Reads

Inhibition of nucleotide pyrophosphatase/phosphodiesterase 1: implications for developing a calcium pyrophosphate deposition disease modifying drug.

Rheumatology (Oxford) 2018 08;57(8):1472-1480

Department of Rheumatology, Tel Aviv University, Tel Aviv, Israel.

Objectives: Calcium pyrophosphate deposition (CPPD) is associated with osteoarthritis and is the cause of a common inflammatory articular disease. Ecto-nucleotide pyrophosphatase/phosphodiesterase 1 (eNPP1) is the major ecto-pyrophosphatase in chondrocytes and cartilage-derived matrix vesicles (MVs). Thus, eNPP1 is a principle contributor to extracellular pyrophosphate levels and a potential target for interventions aimed at preventing CPPD. Read More

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http://dx.doi.org/10.1093/rheumatology/key092DOI Listing
August 2018
8 Reads

Therapy for CPPD: Options and Evidence.

Curr Rheumatol Rep 2018 Apr 19;20(6):31. Epub 2018 Apr 19.

Instituto de Investigación Sanitaria y Biomédica de Alicante (ISABIAL), Universidad Miguel Hernández, Alicante, Spain.

Purpose Of Review: Current evidence and accumulated experience for the management of calcium pyrophosphate deposition disease (CPPD) are presented.

Recent Findings: Contrary to other rheumatic inflammatory conditions that account for high interest and growing research, advances in treating CPPD are still very limited and mostly derive from those achieved in gout. Once formed, calcium pyrophosphate crystals cannot be dissolved; therefore, management relies on the control of crystal-derived inflammation. Read More

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http://dx.doi.org/10.1007/s11926-018-0739-zDOI Listing
April 2018
10 Reads

Pseudogout among Patients Fulfilling a Billing Code Algorithm for Calcium Pyrophosphate Deposition Disease.

Rheumatol Int 2018 Jun 17;38(6):1083-1088. Epub 2018 Apr 17.

Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, 60 Fenwood Road, Suite 6016, Boston, MA, 02115, USA.

To test the performance of a billing claims-based calcium pyrophosphate deposition disease (CPPD) algorithm for identifying pseudogout. We applied a published CPPD algorithm at an academic institution and randomly selected 100 patients for electronic medical record review for 3 phenotypes: (1) definite/probable CPPD, (2) definite/probable pseudogout; (3) definite pseudogout. Clinical data were recorded and positive predictive value (PPV) (95% CI) for each phenotype was calculated. Read More

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http://dx.doi.org/10.1007/s00296-018-4029-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5975352PMC
June 2018
4 Reads

Magnesium disorders can cause calcium pyrophosphate deposition disease: A case report and literature review.

Eur J Rheumatol 2018 Mar 29;5(1):53-57. Epub 2017 Aug 29.

Division of Rheumatology, Department of Internal Medicine, University of Missouri, Columbia, MO, USA.

Calcium pyrophosphate deposition (CPPD) disease, also known as pseudogout, is one of the most common forms of inflammatory arthritis. A variety of comorbidities and metabolic conditions have been recognized to predispose to CPPD. We describe here a patient with chronic CPP arthritis due to hypomagnesemia, which is one of the metabolic etiologies associated with CPPD, especially in younger patients. Read More

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http://dx.doi.org/10.5152/eurjrheum.2017.16116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895153PMC
March 2018
4 Reads

Detection of calcium pyrophosphate dihydrate crystals in knee meniscus by dual-energy computed tomography.

J Orthop Surg Res 2018 Apr 5;13(1):73. Epub 2018 Apr 5.

Department of Clinical Biomechanics, Keio University School of Medicine, 35 Shinamomachi, Shinjyuku, Tokyo, Japan.

Background: Calcium pyrophosphate dihydrate (CPPD) crystals are commonly observed in osteoarthritic joints. The aim of our study was to investigate the efficacy of a dual-energy computed tomography (DECT) for detecting CPPD crystals in knee meniscus.

Methods: Twenty-six patients undergoing primary total knee arthroplasty were included in the study. Read More

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http://dx.doi.org/10.1186/s13018-018-0787-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5887196PMC
April 2018
5 Reads

Pseudogout - a rare manifestation of hungry bone syndrome after focused parathyroidectomy.

Ann R Coll Surg Engl 2018 May 1;100(5):e106-e108. Epub 2018 Apr 1.

Division of General Surgery (Thyroid and Endocrine Surgery), University Surgical Cluster, Department of Surgery, National University Health System , Singapore.

Pseudogout, also known as calcium pyrophosphate deposition disease, is a rheumatological condition arising from accumulation of calcium pyrophosphate dihydrate crystals in connective tissues. We present a case of a 56-year-old Bangladeshi woman who underwent focused right inferior parathyroidectomy for primary hyperparathyroidism from a right inferior parathyroid adenoma. On the first post-operative day, she complained of left elbow painful swelling with redness and warmth. Read More

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http://dx.doi.org/10.1308/rcsann.2018.0028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5956596PMC
May 2018
6 Reads

Tophaceous Chondrocalcinosis Mimicking Chronic External Otitis.

Otol Neurotol 2018 Jun;39(5):e407-e409

Audiology Unit, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, University of Milan, Milan.

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http://dx.doi.org/10.1097/MAO.0000000000001776DOI Listing
June 2018
4 Reads

Identification of calcium pyrophosphate deposition disease (CPPD) by ultrasound: reliability of the OMERACT definitions in an extended set of joints-an international multiobserver study by the OMERACT Calcium Pyrophosphate Deposition Disease Ultrasound Subtask Force.

Ann Rheum Dis 2018 Aug 13;77(8):1194-1199. Epub 2018 Mar 13.

Rheumatology Unit, Università di Torino, Torino, Italy.

Objectives: To assess the reliability of the OMERACT ultrasound (US) definitions for the identification of calcium pyrophosphate deposition disease (CPPD) at the metacarpal-phalangeal, triangular fibrocartilage of the wrist (TFC), acromioclavicular (AC) and hip joints.

Methods: A web-based exercise and subsequent patient-based exercise were carried out. A panel of 30 OMERACT members, participated at the web-based exercise by evaluating twice a set of US images for the presence/absence of CPPD. Read More

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http://ard.bmj.com/lookup/doi/10.1136/annrheumdis-2017-21254
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http://dx.doi.org/10.1136/annrheumdis-2017-212542DOI Listing
August 2018
30 Reads

Unusual cause of neck pain.

BMJ Case Rep 2018 Mar 5;2018. Epub 2018 Mar 5.

Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

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http://dx.doi.org/10.1136/bcr-2018-224183DOI Listing
March 2018
6 Reads

Injury to the axillary and suprascapular nerves in rotator cuff arthropathy and after reverse shoulder arthroplasty: a prospective electromyographic analysis.

J Shoulder Elbow Surg 2018 Jul 21;27(7):1275-1282. Epub 2018 Feb 21.

Department of Orthopaedic Surgery and Traumatology, Shoulder and Elbow Unit, Clínico San Carlos Hospital, Madrid, Spain; Surgery Department, Complutense University, Madrid, Spain.

Background: Neurologic pre- and postoperative injuries to the axillary and/or suprascapular nerve (SSN) have a higher incidence than expected and may lead to significantly decreased functional outcomes and increased risk of reverse shoulder arthroplasty (RSA) failure.

Methods: Patients who underwent a RSA for rotator cuff tear arthropathy (RCTA) were included from December 2014 to December 2015. This study focused on the clinical (Constant score), radiographic, and pre- and postoperative electromyographic evaluations at 3 and 6 months. Read More

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http://dx.doi.org/10.1016/j.jse.2017.12.030DOI Listing
July 2018
7 Reads

Optical spectral transmission to assess inflammation in hand and wrist joints of rheumatoid arthritis patients.

Rheumatology (Oxford) 2018 05;57(5):865-872

Department of Rheumatology and Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

Objective: To develop an optical spectral transmission (OST) model to measure joint inflammation, and thus disease activity, as well as to evaluate (patho-)physiological findings that could lead to misclassification of inflammation.

Methods: Forty-six RA patients were included in this cross-sectional study, where US scores, duplicate OST measurements and 28-joint DAS (DAS28) were acquired. With US as a reference standard, the diagnostic performance of OST in detecting inflammation at the joint level was evaluated using receiver operating characteristic (ROC) curve analyses. Read More

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http://dx.doi.org/10.1093/rheumatology/kex531DOI Listing
May 2018
11 Reads

An Unusual Case of Acute Chondrocalcinosis in Wrist Joint Presenting as Cellulitis.

Cureus 2017 Dec 6;9(12):e1916. Epub 2017 Dec 6.

Internal Medicine, Newark Beth Israel Medical Center.

Chondrocalcinosis is a common arthritic disorder among elderly patients. We present a case of a 71-year-old woman presenting with an acute episode of the left forearm with hand swelling. A provisional diagnosis of cellulitis was made and the patient was started on intravenous antibiotics. Read More

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http://dx.doi.org/10.7759/cureus.1916DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5800752PMC
December 2017
4 Reads

Pseudogout Attack after Pegfilgrastim Administration in Anaplastic Large Cell Lymphoma.

Intern Med 2018 Jun 9;57(12):1779-1782. Epub 2018 Feb 9.

Division of Gastroenterology and Hematology/Oncology, Department of Medicine, Asahikawa Medical University, Japan.

A 67-year-old man with relapsed anaplastic large cell lymphoma received salvage chemotherapy, and pegfilgrastim was used to prevent febrile neutropenia. On day 18 of chemotherapy, he developed a pseudogout attack. Although the first symptoms improved, another pseudogout attack occurred when he received the second course of chemotherapy and pegfilgrastim. Read More

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http://dx.doi.org/10.2169/internalmedicine.9362-17DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6047990PMC
June 2018
2 Reads

Differential diagnostic perspectives provided by en face microscopic examination of articular surface defects.

Clin Rheumatol 2018 Mar 4;37(3):831-836. Epub 2018 Feb 4.

Department of Vertebrate Paleontology, Carnegie Museum, Pittsburgh, PA, 15213, USA.

Surface defects have a central position in diagnosis of articular pathology. Recognizing the limitations of standard radiologic techniques and those imposed by positioning and averaging artifacts on CT evaluation, direct visualization of surface defects was pursued to identify disease characteristics that would facilitate interpretation of radiologic findings. Epi-illumination surface microscopy was utilized to examine macroscopically recognized articular surface defects in individuals in the Hamann-Todd, Terry, and Huntington human skeletal collections with previously verified diagnoses of rheumatoid arthritis, spondyloarthropathy, juvenile inflammatory arthritis (JIA), calcium pyrophosphate deposition disease (CPPD), gout, metastatic cancer, multiple myeloma, septic arthritis, tuberculosis, fungal arthritis, histiocytosis and sickle cell anemia (Rothschild and Rothschild Clin Infect Dis 20(5):1402-1408, 1995; Rothschild et al. Read More

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http://dx.doi.org/10.1007/s10067-018-4001-xDOI Listing
March 2018
6 Reads

Outcomes of an anatomic total shoulder arthroplasty with a contralateral reverse total shoulder arthroplasty.

J Shoulder Elbow Surg 2018 Jun 15;27(6):998-1003. Epub 2018 Feb 15.

Department of Orthopaedic Surgery, The Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

Background: It is common for patients to require staged bilateral shoulder arthroplasties. There is a unique cohort of patients who require an anatomic total shoulder arthroplasty (TSA) and a contralateral reverse shoulder arthroplasty (RSA). This study compared the outcomes of patients with a TSA in 1 shoulder and an RSA in the contralateral shoulder. Read More

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http://dx.doi.org/10.1016/j.jse.2017.12.005DOI Listing
June 2018
1 Read

Case report: Calcium pyrophosphate dihydrate deposition of the temporomandibular joint diagnosed by fine-needle aspiration cytology.

Diagn Cytopathol 2018 Jul 2;46(7):610-612. Epub 2018 Feb 2.

Department of Cytology, Karolinska University Hospital, Stockholm, Sweden.

Calcium pyrophosphate dihydrate deposition (CPDD) is the accepted name for a disease that mainly occurs in elderly patients. This disease affects many joints in particular the knee joint. CPDD is extremely rare in the temporomandibular joint (TMJ) with only few cases reported in the English literature. Read More

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http://dx.doi.org/10.1002/dc.23895DOI Listing
July 2018
3 Reads

Concurrence of rheumatoid arthritis and calcium pyrophosphate deposition disease: A case collection and review of the literature.

Semin Arthritis Rheum 2018 08 2;48(1):9-11. Epub 2017 Dec 2.

Division of Rheumatology, Department of Medicine, Medical College of Wisconsin, FOEB, 4th Floor, 9200 Wisconsin Ave, Milwaukee, WI 53226.

Objective: Calcium pyrophosphate deposition disease (CPDD) is arthritis caused by calcium pyrophosphate (CPP) crystal deposition in joints. It is commonly associated with aging as well as a handful of metabolic syndromes. Recent epidemiologic studies suggest a positive association of CPDD and rheumatoid arthritis (RA). Read More

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http://dx.doi.org/10.1016/j.semarthrit.2017.11.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6240440PMC
August 2018
14 Reads

Intraarticular calcifying aponeurotic fibroma of the wrist: mimicking gout or calcium pyrophosphate dihydrate deposition disease.

Skeletal Radiol 2018 May 14;47(5):729-734. Epub 2017 Dec 14.

Department of Radiology, CHA Bundang Medical Center, College of Medicine, CHA University, 59, Yatap-ro, Bundang-gu, Seongnam-si, Gyeonggi-do, 13496, Republic of Korea.

Calcifying aponeurotic fibroma is a rare, benign fibroblastic tumor that typically occurs in the palms of the hands and soles of the feet in children and adolescents. We report an unusual case of a calcifying aponeurotic fibroma with diffuse intra-articular involvement of the carpal joints in a 59-year-old female. Radiographs and computed tomography scans revealed a large lobulated soft tissue mass with multiple stippled calcifications around the carpal joints and numerous erosions of the second to fifth carpometacarpal and intercarpal joints. Read More

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http://dx.doi.org/10.1007/s00256-017-2847-7DOI Listing
May 2018
13 Reads

Genetic analysis of adults heterozygous for ALPL mutations.

J Bone Miner Metab 2018 Nov 13;36(6):723-733. Epub 2017 Dec 13.

Unité de Génétique Constitutionnelle, Service de Biologie, Centre Hospitalier de Versailles, 177 rue de Versailles, 78150, Le Chesnay, France.

Hypophosphatasia (HPP) is a rare inherited metabolic bone disease due to a deficiency of the tissue nonspecific alkaline phosphatase isoenzyme (TNSALP) encoded by the ALPL gene. Patients have consistently low serum alkaline phosphatase (AP), so that this parameter is a good hallmark of the disease. Adult HPP is heterogeneous, and some patients present only mild nonpathognomonic symptoms which are also common in the general population such as joint pain, osteomalacia and osteopenia, chondrocalcinosis, arthropathy and musculoskeletal pain. Read More

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http://dx.doi.org/10.1007/s00774-017-0888-6DOI Listing
November 2018
19 Reads

An investigation of the independent risk factors that differentiate gout from pseudogout in patients with crystal-induced acute arthritis: a cross-sectional study.

Rheumatol Int 2018 Jan 6;38(1):89-95. Epub 2017 Dec 6.

Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj Hospital, Mahidol University, 2 Wanglang Road, Bangkoknoi, Bangkok, 10700, Thailand.

Objectives: To identify independent risk factors that differentiate gout from pseudogout in patients that present with crystal-induced acute arthritis.

Methods: This cross-sectional study was conducted at Siriraj Hospital (Bangkok, Thailand) during the 25 May 2014-28 November 2014 study period. Patients who presented with crystal-induced acute arthritis were eligible for inclusion. Read More

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http://dx.doi.org/10.1007/s00296-017-3891-2DOI Listing
January 2018
11 Reads

Wrist inflammation: a retrospective comparison between septic and non-septic arthritis.

J Hand Surg Eur Vol 2018 May 3;43(4):431-437. Epub 2017 Dec 3.

Singapore General Hospital, Singapore.

This study aims to identify differences in demographics, clinical and laboratory data between wrist septic arthritis and non-septic arthritis in patients admitted for wrist inflammation. A retrospective review of inpatients from May 2012 to April 2015 was conducted. Seventy-seven patients were included. Read More

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http://dx.doi.org/10.1177/1753193417738166DOI Listing
May 2018
13 Reads

Crowned dens syndrome.

Pract Neurol 2018 Feb 24;18(1):57-59. Epub 2017 Nov 24.

Department of Neurology and Neurophysiology, Liverpool Hospital, Liverpool, New South Wales, Australia.

Crowned dens syndrome is a rare presentation of calcium pyrophosphate deposition disease. It is characterised by severe occipital pain and neck stiffness. Acute presentations are typically accompanied by fever and an inflammatory response and hence can be misdiagnosed as polymyalgia rheumatica or meningitis. Read More

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http://dx.doi.org/10.1136/practneurol-2017-001793DOI Listing
February 2018
6 Reads