Search Our Scientific Publications & Authors

J Ayub Med Coll Abbottabad 2018 Oct-Dec;30(4):608-610

Department of Radiology, First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.

Chondroblastoma is an uncommon and benign bone tumour. No more than 10 cases of lumbar chondroblastoma have been reported in the past 20 years. To describe the clinical presentations and radiological features of a rare case of chondroblastoma of the lumbar spine, this study reports one case involving the third lumbar vertebrae. Read More

Clinics (Sao Paulo) 2018 11 29;73:e540. Epub 2018 Nov 29.

Emergency Department, Second Affiliated Hospital of the Zhejiang University School of Medicine, Hangzhou, Zhejiang, 310090.

Objectives: To investigate the diagnosis and treatment of tibial intercondylar chondroblastoma.

Methods: We retrospectively analyzed the diagnosis and treatment of 12 patients with tibial intercondylar chondroblastoma admitted to the orthopedics department from May 2011 to February 2016; among them were 4 males and 3 females aged 10-19 years, with an average age of 15.7 years. Read More

J Foot Ankle Surg 2018 Nov - Dec;57(6):1105-1109

Professor, Department of Orthopedic and Orthopedic Oncology, University of Padova, Padova, Italy. Electronic address:

Chondroblastoma (CB) of the foot is a rare lesion. The purpose of this report was to report a large series from a single institution to analyze clinical, radiographic, and histologic characteristics; treatment; and local recurrence. We present 40 patients (30 males, 10 females; mean age 25 years) diagnosed and treated for CB of the foot from 1975 to 2012. Read More

Cardiovasc Intervent Radiol 2019 Feb 16;42(2):304-307. Epub 2018 Oct 16.

Department of Interventional Radiology, Centre Léon Berard, 28 Prom. Léa Et Napoléon Bullukian, 69008, Lyon, France.

Surgical curettage is currently the standard of care for the chondroblastoma, but in peri-articular tumors it is limited by its morbidity. In this preliminary report, we evaluate the feasibility of percutaneous cryotherapy as an alternative ablative treatment for chondroblastoma. Three patients with a chondroblastoma treated by CT scan-guided cryotherapy are presented in this article. Read More

Adv Anat Pathol 2018 Nov;25(6):400-412

Department of Pathology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA.

Although some soft tissue and bone tumors can be identified based on histologic features alone, immunohistochemistry plays a critical diagnostic role for most mesenchymal tumor types. The discovery of recurrent genomic alterations in many benign and malignant mesenchymal neoplasms has added important biologic insights and expanded the spectrum of some diagnostic subgroups. Some tumors are defined by unique genomic alterations, whereas others share abnormalities that are not tumor-specific and can be observed in a sometimes broad range of biologically unrelated neoplasms. Read More

Head Neck Pathol 2018 Sep 1;12(3):367-377. Epub 2018 Aug 1.

Department of Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 55902, USA.

Giant cell rich lesions of the temporal bone encompass a wide spectrum of disease that includes infectious, reactive, and neoplastic processes. When dealing with any lesion that can potentially involve bone, it is important to understand both the clinical presentation and to correlate the histologic findings with the radiologic imaging. This review discusses the clinical, the pathologic features including the differential diagnosis, and the treatment of some of the more commonly encountered giant cell rich entities in this region. Read More

J Neurooncol 2018 Oct 2;140(1):99-106. Epub 2018 Jul 2.

Department of Orthopedic Oncology, Shanghai Changzheng Hospital, Second Military Medical University, 415 Fengyang Road, Huangpu District, Shanghai, China.

Purpose: Chondroblastoma (CB) in the spine is extremely rare and there is little published information regarding this subject. We attempt to explore the clinical features of spinal CB and address the importance of total resection, especially total en bloc spondylectomy (TES) for the treatment of spinal CB.

Methods: Clinical data of 13 consecutive CB patients who received surgical treatment in our center between January 2006 and December 2016 were reviewed retrospectively. Read More

Clin Orthop Surg 2018 Jun 18;10(2):253-259. Epub 2018 May 18.

Department of Orthopaedic Surgery, Kyoto University, Kyoto, Japan.

Unsintered hydroxyapatite (u-HA) and poly-L-lactide (PLLA) composites (u-HA/PLLA) are osteoconductive and biodegradable. Screw (Super-Fixsorb MX30) and plate (Super-Fixsorb MX40 Mesh) systems made of u-HA/PLLA are typically used in small bones in maxillofacial surgeries. After the resection of bone tumors in larger bones, reconstructions with β-tricalcium phosphate (β-TCP) implants of strong compression resistance have been reported. Read More

Int J Surg Pathol 2018 Dec 18;26(8):766-771. Epub 2018 May 18.

1 University of Pennsylvania, Philadelphia, PA, USA.

Clear cell chondrosarcoma (CCCS) is a rare variant of conventional chondrosarcoma with low-grade malignant features that may be confused radiographically and histologically with chondroblastoma. We report a case of a 50-year-old female who presented with 6 months of left hip pain. Initial radiographs demonstrated an osteolytic lesion with adjacent area of sclerosis in the proximal left femur. Read More

J Surg Oncol 2018 Jun 3;117(8):1786-1798. Epub 2018 May 3.

Queen Elizabeth II Health Sciences Center, Halifax Infirmary, Dalhousie University, Halifax, Nova Scotia, Canada.

Bone tumors are relatively rare in the foot and ankle region. Many of them present as cystic lesions on plain films. Due to the relative rarity of these lesions and the complex anatomy of the foot and ankle region, identification of such lesions is often delayed or they get misdiagnosed and mismanaged. Read More

Medicine (Baltimore) 2018 Apr;97(17):e0336

Department of Radiology.

Chondroblastoma is a rare benign tumor, consisting of tissue resembling foetal cartilage, and arising in the epiphyses, or apophyses of long tubular bone. However, chondroblastoma of the cortex of the long bone metaphysis is extremely rare.A 15-year-old girl presented a 10-month history of intermittent knee pain and without mobility limitation. Read More

Clin Orthop Relat Res 2018 03;476(3):568-577

V. Hegde, Z. D. C. Burke, H. Y. Park, S. D. Zoller, D. Johansen, B. V. Kelley, N. M. Bernthal, Department of Orthopaedic Surgery, University of California-Los Angeles, Santa Monica, CA, USA B. D Levine, K. Motamedi, L. L. Seeger, Department of Radiological Sciences, University of California-Los Angeles, Los Angeles, CA, USA N. C. Federman, Department of Pediatrics, University of California-Los Angeles, Los Angeles, CA, USA S. D. Nelson, Department of Pathology, University of California-Los Angeles, Santa Monica, CA, USA.

Background: Although there is widespread acceptance of core needle biopsy (CNB) for diagnosing solid tumors, there is reluctance by some clinicians to use CNB for aneurysmal bone cysts (ABCs) as a result of concerns of safety (bleeding, nerve injury, fracture, readmission, or infection) and reliability, particularly to rule out malignant diagnoses like telangiectatic osteosarcoma. This is especially true when CNB tissue is sent from an outside hospital, where the technique used to obtain the tissue may be spurious.

Questions/purposes: (1) Is CNB effective (provided adequate information to indicate appropriate surgical treatment without further open biopsy) as an initial diagnostic test for ABC? (2) Is CNB accurate (pathology consistent with the subsequent definitive surgical pathologic diagnosis) in differentiating between benign lesions such as primary or secondary ABCs and malignant radiolucent lesions such as telangiectatic osteosarcoma? (3) What are the complications of CNB? (4) Is there any difference in the effectiveness or accuracy of CNB performed at outside institutions when compared with a referral center?

Methods: A retrospective study of our musculoskeletal tumor board pathology database (1990-2016) was performed using search criteria "aneurysmal bone cyst" or "telangiectatic osteosarcoma. Read More

J Foot Ankle Surg 2018 Mar - Apr;57(2):396-400. Epub 2018 Jan 4.

Orthopedic Surgeon, Department of Orthopedic Surgery, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea. Electronic address:

Chondroblastomas of the talus can lead to joint collapse and are often treated using curettage and bone grafting. In the present report, we describe the case of a 19-year-old female with a large chondroblastoma of the talus associated with a secondary aneurysmal cyst. We treated the large cartilage lesion, which involved most of the talus, with an iliac bone graft combined with bone cement to fill the large bone defect and preserve the subchondral bone of the articular surface of the dome of the talus. Read More

Skeletal Radiol 2018 Jun 6;47(6):853-857. Epub 2018 Jan 6.

Department of Pathology, Hospital Universitario de León, León, Spain.

A chondroblastoma-like osteosarcoma (CLO) in the proximal epiphysis and metaphysis of the tibia in a 30-year-old male is presented. With a wrong diagnosis of chondroblastoma, an aggressive curettage was performed. Later, the patient refused en-bloc resection. Read More

Pathologe 2018 Mar;39(2):132-138

Knochentumor-Referenzzentrum und DÖSAK-Zentralregister am Institut für Pathologie, Universitätsspital Basel, Schoenbeinstraße 40, 4031, Basel, Schweiz.

Chondroblastomas are very rare benign primary bone tumors occurring preferentially in the epiphyses or apophyses of long bones in children and adolescents. In most cases the typical histological and imaging findings lead to a correct diagnosis that may be substantiated by demonstrating the highly specific point mutation in the H3F3B gene (p.K36M), either by sequencing or immunohistochemistry. Read More

Ann Acad Med Singapore 2017 Oct;46(10):410-412

Department of Diagnostic Imaging, National University Hospital, Singapore.

J Am Podiatr Med Assoc 2017 Sep;107(5):440-445

We present a rare case of calcaneal chondroblastoma with subsequent surgical revision after graft rejection in a 13-year-old boy. Complications were encountered after the injectable bone graft filler was placed in the calcaneus after curettage. With noted subsequent sinus tract formation, revision surgery was performed that involved dissection of the sinus tract, removal of bone void filler, and application of demineralized bone matrix sponge human allograft soaked in vancomycin-impregnated saline. Read More

J Clin Orthop Trauma 2017 Aug 24;8(Suppl 1):S48-S52. Epub 2017 Jul 24.

Department of Applied Clinical Science & Biotechnology, University of L'Aquila, Piazzale Salvatore Tommasi 1, L'Aquila, Italy.

Introduction: Chondroblastoma (also known as Codman tumor) is a rare intermediate grade cartilaginous neoplasm, representing less than 1% of all primary bone tumors; it characteristically arises in the epiphysis or apophysis of a long bone in young patients, predominantly males. The most frequent location of chondroblastoma is the humerus (70% incidence rate) and more rarely it is located in the pelvis. When it affects the hip, the triradiate cartilage is the most common site. Read More

Head Neck 2017 11 24;39(11):2171-2179. Epub 2017 Jul 24.

Department of Radiology, Seoul National University Hospital, Seoul, Korea.

Background: Chondroblastoma commonly involves the temporal bone in the craniofacial region, but its imaging features have not been elucidated. This study aimed to describe the imaging features of temporal bone chondroblastoma with their pathologic correlation.

Methods: Radiopathologic correlation was performed in 5 patients with temporal bone chondroblastoma from our database and in 11 patients identified through a PubMed search. Read More

Eur J Orthop Surg Traumatol 2017 Aug 20;27(6):843-849. Epub 2017 Jun 20.

Department of Orthopaedics and Orthopaedic Oncology, University of Padova, Via Giustiniani 3, 35128, Padua, Italy.

Purpose: Chondroblastoma (CB) is a rare benign tumor that occurs most commonly in the second decade of life. No studies on CB in adulthood have been reported. Our purposes were to report a single-institution experience on CB in adults and to discuss the clinical and imaging findings, type of treatment, oncologic and functional outcomes. Read More

Semin Nucl Med 2017 07 12;47(4):322-351. Epub 2017 Apr 12.

Department of Radiology and Nuclear Medicine, Deventer Ziekenhuis, Deventer, The Netherlands.

Positron emission tomography with the radiotracer F-fluoro-2-deoxy-d-glucose (FDG) plays an important role in the evaluation of bone pathology. However, FDG is not a cancer-specific agent, and knowledge of the differential diagnosis of benign FDG-avid bone alterations that may resemble malignancy is important for correct patient management, including the avoidance of unnecessary additional invasive tests such as bone biopsy. This review summarizes and illustrates the spectrum of benign bone conditions that may be FDG-avid and mimic malignancy, including osteomyelitis, bone lesions due to benign systemic diseases (Brown tumor, Erdheim-Chester disease, Gaucher disease, gout and other types of arthritis, Langerhans cell histiocytosis, and sarcoidosis), benign primary bone lesions (bone cysts, chondroblastoma, chondromyxoid fibroma, desmoplastic fibroma, enchondroma, giant cell tumor and granuloma, hemangioma, nonossifying fibroma, and osteoid osteoma and osteoblastoma), and a group of miscellaneous benign bone conditions (post bone marrow biopsy or harvest status, bone marrow hyperplasia, fibrous dysplasia, fractures, osteonecrosis, Paget disease of bone, particle disease, and Schmorl nodes). Read More

JBJS Rev 2017 05;5(5):e4

1Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina2Department of Orthopaedic Surgery, Duke University Hospital, Durham, North Carolina.

Neurochirurgie 2017 May 11;63(2):88-90. Epub 2017 May 11.

Service d'ORL et chirurgie cervico-faciale, hôpital Charles-Nicolle, CHU de Rouen, 76031 Rouen, France.

Introduction: Chondroblastoma is a rare tumor that can involve the temporal bone. Because it is a benign tumor, functional surgery must be proposed. We report a case of a patient with a massive chondroblastoma operated on with preservation of the facial nerve, and description of the surgical technique. Read More

Asian J Neurosurg 2017 Apr-Jun;12(2):266-269

Department of Neurosurgery, Grant Medical College and Sir J. J. Group of Hospitals, Byculla, Mumbai, Maharashtra, India.

This case highlights a rare possibility of occurrence of chondroblastoma, a bony tumor, at an uncommon location. Extraosseous, soft tissue location of this bony tumor is rare and more so for intracranial intra-axial location. We report a case of an intra-axial frontal lobe lesion, histologically proven to be an extraosseous chondroblastoma. Read More

Hand (N Y) 2017 03 8;12(2):NP14-NP18. Epub 2016 Jul 8.

Mayo Clinic, Rochester, MN, USA.

Chondroblastomas are benign tumors that typically occur in the epiphysis of long bones. Carpal bone chondroblastomas are very rare and are known to have less aggressive behavior with no evidence of recurrence reported. We present a case of a recurrent chondroblastoma in the capitate that was treated with repeat curettage, application of phenol, and bone grafting. Read More

Orthop Surg 2017 Feb 16;9(1):97-102. Epub 2017 Mar 16.

Department of Orthopaedics, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, China.

Objective: To evaluate the effectiveness of intramedullary nailing for benign lesions of the proximal femur.

Method: A retrospective analysis was carried out on 68 cases of benign lesions in the proximal femur at our hospital from April 2002 to April 2013 (38 men and 30 women). Mean age at surgery was 35. Read More

Ophthalmic Plast Reconstr Surg 2017 May/Jun;33(3S Suppl 1):S114-S116

Departments of *Ophthalmology and †Neurosurgery, Maywood, Illinois, U.S.A.

A 56-year-old male with history of chronic sinusitis was found to have a 3 cm left orbital lesion on CT. Subsequent MRI demonstrated a multilobulated enhancing soft tissue lesion at the superotemporal region of the left orbit. Initial biopsy was reported as a low-grade sarcoma. Read More

World Neurosurg 2017 Feb 18;98:867.e1-867.e3. Epub 2016 Dec 18.

Department of Neurosurgery, West China Hospital of Sichuan University, Chengdu, Sichuan, China. Electronic address:

We present a rare case of giant soap bubble-shaped cystic lesion in the craniofacial region in an adult female. Histopathologic examination revealed the tumor consisted of 3 components including chondroblastoma, chondromyxoid fibroma, and hemorrhagic aneurysmal bone cyst. The present case is rare in terms of size, location, and histopathologic diagnosis, which is probably the result of underdeveloped health care in the remote place. Read More

Skeletal Radiol 2017 Mar 13;46(3):367-372. Epub 2016 Dec 13.

Department of Radiology, University Hospital of Strasbourg, 1 avenue Moliere, 67098, Strasbourg, France.

Chondroblastoma is a rare benign cartilage neoplasm that arises from the appendicular skeleton in the vast majority of the cases (80%). Chondroblastoma of the spine is an even more rare condition (30 cases reported), and vertebral chondroblastomas, unlike chondroblastomas of the extremities, present with the appearance of an aggressive tumor on CT and MR imaging and occur at least a decade later. Even though vertebral chondroblastomas are very uncommon tumors, they should nonetheless be included in the differential diagnosis when encountered with an aggressive vertebral mass, and a histological confirmation should be performed. Read More

Acta Orthop Traumatol Turc 2016 Dec 10;50(6):691-693. Epub 2016 Dec 10.

Department of Pathology, Oncology State Hospital, Ankara, Turkey.

We present a 37-year-old patient with a chondroblastoma in his right acromion. The acromion is an unusual site for this type of tumor and the typical surgical treatment involves resection of the involved acromion bone. The patient was surgically treated with resection of the right acromion and autogenous iliac bone grafting. Read More

Laryngoscope 2017 10 26;127(10):2340-2346. Epub 2016 Nov 26.

Department of Otorhinolaryngology, Mayo Clinic School of Medicine, Rochester, Minnesota, U.S.A.

Objectives: To elucidate the clinical behavior, treatment, and outcomes of tenosynovial giant cell tumors (TGCT) involving the temporomandibular joint (TMJ) and adjacent temporal bone.

Study Design: Retrospective case series with histopathologic review.

Methods: A retrospective chart review was performed identifying and collecting data from all cases of TGCT involving the TMJ and adjacent temporal bone that were treated at the authors' center between January 1960 and December 2015. Read More

Foot Ankle Spec 2017 Jun 25;10(3):274-277. Epub 2016 Oct 25.

Hospital Clinico, University of Chile, Independencia, Santiago (LBM).

Chondroblastomas are benign bone tumors that are usually located at epiphyseal regions of long bones, and are rarely located at the talus. The usual treatment consists of curettage and filling of the bone defect with bone either bone grafts or some other material, such as cement. The authors present a case of a massive chondroblastma of the talus, extending outside of bone boundaries and with a huge soft tissue mass and invasion of the adjacent calcaneus. Read More

J Can Chiropr Assoc 2016 Sep;60(3):226-232

Private practice, Surrey, BC.

Objective: To present a case of chronic elbow pain as a result of a hidden underlying osteochondral defect.

Clinical Features: A 17-year old baseball player presented with chronic lateral elbow pain. Examination revealed swelling of the elbow with signs of possible ligament, muscle, and tendon injury. Read More

Asia Ocean J Nucl Med Biol 2015 ;3(2):120-4

Department of Diagnostic Radiology and Nuclear Medicine, Tokyo Medical and Dental University, Yushima, Bunkyo-ku, Tokyo, Japan.

Temporal bone chondroblastoma is an extremely rare benign bone tumor. We encountered two cases showing similar imaging findings on computed tomography (CT), magnetic resonance imaging (MRI), and dual-time-point (18)F-fluorodeoxyglucose ((18)F-FDG) positron emission tomography (PET)/CT. In both cases, CT images revealed temporal bone defects and sclerotic changes around the tumor. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2016 Jun;30(6):675-679

Department of Orthopaedic Oncology Surgery, Beijing Jishuitan Hospital, Beijing, 100035, P.R.China.

Objective: To compare the healing process and clinical results of bioactive glass and allogenic bone in the repair of bone defects after benign bone tumor curettage.

Methods: Between November 2011 and December 2012, 20 patients with benign bone tumor received bioactive glass and allogenic bone for repair of bone defects after benign bone tumor curettage. There were 17 males and 3 females, aged 9-68 years (median, 18. Read More

Radiologe 2016 Jun;56(6):476-88

Pathologisches Institut, Universitätsklinik Freiburg, Breisacher Str. 115, 79106, Freiburg, Deutschland.

Primary cartilage-forming tumors of the bone are frequent entities in the daily work of skeletal radiologists. This article describes the correlation of pathology and radiology in cartilage-forming skeletal tumors, in particular, enchondroma, osteochondroma, periosteal chondromas, chondroblastoma and various forms of chondrosarcoma. After reading, the radiologist should be able to deduce the different patterns of cartilage tumors on radiographs, CT, and MRI from the pathological aspects. Read More

Oncol Lett 2016 Feb 7;11(2):1481-1485. Epub 2016 Jan 7.

Department of Orthopedics, The First Affiliated Hospital of Nanchang University, Artificial Joints Engineering and Technology Research Center of Jiangxi Province, Nanchang, Jiangxi 330006, P.R. China.

The patella is an unusual location for primary and metastatic bone tumors to develop. The most frequently encountered primary osteolytic lesions at the patella include giant cell tumors of the bone (GCT), chondroblastoma and aneurysmal bone cysts (ABC). However, the presentation of an ABC originating secondary to a GCT at the patella is rare. Read More

Clin Orthop Relat Res 2017 Mar;475(3):760-766

Carlos E. Ottolenghi Institute of Orthopedics, Italian Hospital of Buenos Aires, Potosí 4247 (1199), Buenos Aires, Argentina.

Background: Chondroblastoma is an uncommon, benign, but locally aggressive bone tumor that occurs in the apophyses or epiphyses of long bones, primarily in young patients. Although some are treated with large resections, aggressive curettage and bone grafting are more commonly performed to preserve the involved joint. Such intralesional resection may result in damage to the growth plate and articular cartilage, which can result in painful arthritis. Read More

J Belg Soc Radiol 2016 Feb 3;100(1):16. Epub 2016 Feb 3.

Hospital AZ Sint-Jan AV Bruges, BE.

Chondroblastoma is a rare benign bone tumor, most often localized in the epiphysis of long bones. We report a case of atraumatic shoulder pain in a 17-year old soccer player. This chondroblastoma case demonstrates the difficult differentiation of chondroblastoma from giant cell tumor and clear cell chondrosarcoma and highlights possible pitfalls and clinical importance. Read More

Auris Nasus Larynx 2016 Aug 29;43(4):468-71. Epub 2015 Dec 29.

Department of Otolaryngology, Head and Neck Surgery, Kyoto University, Graduate School of Medicine, Japan.

We report a case of temporal bone chondroblastoma that was totally invisible on MRI. The patient was a 64-year-old man who presented with several months history of vertigo. The CT scan with bone window setting showed destruction of the temporomandibular joint, the floor of the middle cranial fossa, and the superior semicircular canal. Read More

Cranio 2015 Oct 29;33(4):306-11. Epub 2015 Dec 29.

Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, College of Dentistry, Yonsei University , Seoul, Korea.

Aim: Chondroblastoma is a rare, benign bone tumor that accounts for approximately 1% of all primary bone tumors. Chondroblastoma that occurs at the temporomandibular joint can exhibit symptoms similar to those associated with other temporomandibular disorders. This case study aims to present an eight-year followup of chondroblastoma occurring at the temporomandibular joint. Read More

J Neurol Surg Rep 2015 Nov 9;76(2):e258-64. Epub 2015 Oct 9.

Department of Neurological Surgery, UC Davis School of Medicine, Sacramento, California, United States.

Background and Importance Chondroblastoma is a benign primary bone tumor that typically develops in the epiphyses of long bones. Chondroblastoma of the craniofacial skeleton is extremely rare, with most cases occurring in the squamosal portion of the temporal bone. In this report, we describe the first case of chondroblastoma of the clivus presenting with cranial neuropathy that was treated with endoscopic endonasal resection. Read More

J Craniofac Surg 2015 Nov;26(8):e689-90

*Ear Nose and Throat Clinic †Pathology Clinic ‡Department of Otorhinolaryngology, Radiology Clinic, Istanbul Training and Research Hospital, Istanbul, Turkey.

Chondroblastoma is a highly destructive tumor originating from immature cartilage cells. Although chondroblastoma is defined as a benign tumor, it may exhibit malign tumor behaviors such as invasion or metastasis on neighboring structures. Magnetic resonance (MR) image is a solid mass lesion, which included heterogeneous hypointense in T2A and heterogeneous minimal hyperintense in T1A with destructive expansile characteristics and millimetric calcifications. Read More

J Cancer Res Ther 2015 Jul-Sep;11(3):669

Department of Orthopaedics, Kasturba Medical College, Manipal University, Manipal, Karnataka, India.

Benign Chondroblastoma generally occur in the epiphysis of long bones and rarely arise in carpal bones. We report a young male with chondroblastoma of scaphoid treated with curettage, bone grafting and K-wire fixation. At the last follow-up, 4 years after surgery, the patient was asymptomatic without recurrence. Read More

J Cancer Res Ther 2015 Jul-Sep;11(3):660

Department of Radiology, Tata Memorial Centre, Dr. Ernest Borges Marg, Parel, Mumbai, Maharashtra, India.

Chondroblastoma is a rare, benign tumor derived from chondroblasts, commonly presenting in the second decade of life. It is usually found in the epiphysis or apophysis of long bones; however, it may rarely affect flat bones like scapula. Occasionally a histologically typical chondroblastoma may exhibit an aggressive behavior that is not normally associated with benign tumors such as a large size, pulmonary metastases, joint and soft-tissue infiltration and local recurrence. Read More

Clin Neuropathol 2016 Jan-Feb;35(1):42-3

Nihon Jibiinkoka Gakkai Kaiho 2015 Mar;118(3):213-8

We report a case of chondroblastoma of the middle cranial fossa, probably arising from the (infra) mandibular fossa, and expanding to the attic and external auditory canal that was successfully removed using a middle cranial fossa approach. No recurrences occurred during an 8-year postoperative follow-up period. Initial biopsy findings suggested a pathological diagnosis of giant cell tumor that was later confirmed to be a chondroblastoma based on an immunohistochemical study of S-100. Read More

World Neurosurg 2016 Jan 1;85:364.e11-8. Epub 2015 Sep 1.

Division of Neurosurgery, Department of Neurosciences, Medical University of South Carolina, Charleston, South Carolina, USA. Electronic address:

Background: Calcifying pseudoneoplasm of the neuroaxis (CAPNON) is a rare, slow-growing tumor of a fibro-osseous origin that may present anywhere in the neuroaxis. Although typically benign, symptoms of CAPNONs typically present secondary to compression and surrounding mass effect. Histologically, the tumor has the characteristics of a foreign body reaction with giant cells, ossification, and the formation of psammoma bodies. Read More

Skeletal Radiol 2015 Jul 8;44(7):1045-50. Epub 2015 Apr 8.

Mallinckrodt Institute of Radiology, Washington University School of Medicine, 510 South Kingshighway Boulevard, Campus Box 8131, St. Louis, MO, 63110, USA,

Background: Chondroblastoma is a benign tumor classically located within the epiphysis of the long bones. The tumor is believed to arise from immature cells of the epiphyseal plate. Purely metaphyseal or diaphyseal chondroblastoma is exceedingly uncommon, occurring in approximately 2% of chondroblastoma cases. Read More