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Cureus 2022 Feb 21;14(2):e22451. Epub 2022 Feb 21.

Department of Neurological Surgery, University of Washington, Seattle, USA.

Chondroblastoma is a rare bone tumor, most often found in epiphyseal plates of long bones. It has infrequently been reported in the skull, most often in the temporal bone. We present a case of chondroblastoma of the occipital bone in a pediatric patient presenting with a bony protuberance of the occiput and imaging consistent with obstructive hydrocephalus, which persisted even after removal of the obstructing tumor. Read More

J Clin Imaging Sci 2021 4;11:66. Epub 2021 Dec 4.

Department of Radiology, Mayo Clinic Arizona, Phoenix, Arizona, United States.

There is a wide spectrum of head and neck cartilaginous lesions which include both neoplastic and nonneoplastic processes. Cartilaginous tumors of the head and neck are uncommon, posing a diagnostic challenge. Benign cartilaginous tumors that may occur in the head and neck include chondroma, chondroblastoma, chondromyxoid fibroma, osteochondroma, and synovial chondromatosis. Read More

Cureus 2021 Nov 11;13(11):e19467. Epub 2021 Nov 11.

Department of Surgery, Ministry of the National Guard - Health Affairs, Jeddah, SAU.

We present a case of chondroblastoma-like chondroma (CLC) of soft tissue that manifested as a palmar mass on the left hand of an 84-year-old man. Physical examination, imaging investigation, and needle biopsy initially suggested a giant cell tumor of the tendon sheath, until a correct diagnosis was made based on excised specimen histology. The patient underwent a marginal excision for soft-tissue mass removal. Read More

J Am Podiatr Med Assoc 2021 Sep;111(5)

Chondroblastoma located in the talus is a rare incidence, and due to the weightbearing duty of the talus, the results of local excision may not be favorable. While the volume of the tumor increases, more sophisticated techniques may be undertaken. Cell-free matrix application for extensive osteochondral defects is gaining popularity for its structural support when it is used with microfracture and autograft application. Read More

Int Orthop 2022 03 19;46(3):653-660. Epub 2021 Nov 19.

Department of Orthopaedics and Traumatology, Kasralainy School of Medicine, Cairo University, Cairo, Egypt.

Purpose: Femoral head chondroblastoma poses a surgical challenge. Anatomical limitations may lead to increased risk of local recurrence, damage to the articular cartilage, growth disturbances, and/or avascular necrosis (AVN). We are presenting our results with surgical hip dislocation approach with the aim to evaluate its efficacy in preventing recurrence and its safety, preserving a functional hip joint and avoiding complications. Read More

Acta Medica (Hradec Kralove) 2021 ;64(3):170-173

The Jessenius Medical Faculty of Comenius University in Martin, Slovakia.

Introduction: Temporal bone chondroblastoma is a rare, locally aggressive tumour originating from immature cartilage, which recurs to a high degree. Treatment is surgical. Radiotherapy is reserved for recurrence. Read More

Radiol Case Rep 2021 Dec 2;16(12):3729-3733. Epub 2021 Oct 2.

Department of Radiology, NYC Health + Hospital / Harlem, New York, USA.

Chondroblastoma is an uncommon osseous neoplasm that accounts for less than 1% of all bone tumors. Characteristically it arises in the epiphysis or apophysis of long bones in young patients and may extend into the metaphysis. A sixteen-year-old male presents with a 1-year history of left knee pain associated with joint stiffness and interfering with performing daily activities. Read More

Open Med (Wars) 2021 13;16(1):1372-1377. Epub 2021 Sep 13.

Department of Oral and Maxillofacial Surgery, Stomatological Hospital, Southern Medical University, Guangzhou 510280, China.

Chondroblastoma is one of the uncommon benign bone tumors, particularly when located in the mandibular condyle. Such a location makes its diagnosis difficult when based on only its clinical presentation and radiographic features. Herein the current report presents a case of chondroblastoma of the mandibular condyle: its clinical presentation, radiographic features, and immediate condylar reconstruction after resection. Read More

Eur J Radiol 2021 Nov 17;144:109950. Epub 2021 Sep 17.

Department of Radiology and Physical Medicine, Hospital Virgen de las Nieves, University of Granada, Spain.

Purpose: To present our experience on the implementation of radiofrequency thermal ablation (RFA) for the treatment of chondroblastoma.

Materials And Methods: This case series includes 12 patients (10 males) with chondroblastoma using RFA under CT guidance. Tumours were located in the humeral head (3), femoral head (2), distal femoral epiphysis (4), tibial epiphysis (2) and calcaneus (1). Read More

Foot (Edinb) 2021 Dec 29;49:101845. Epub 2021 Jun 29.

Radiology & Orthopeadic Surgery, UT Southwestern, 5323 Harry Hines Blvd, Dallas, TX, United States. Electronic address:

Bone tumors and tumor-like lesions (pseudotumors) are not uncommonly encountered as asymptomatic findings on imaging, or as symptomatic lesions clinically. Radiographic imaging is the first diagnostic tool for their management strategy, since the symptoms are commonly non-specific, such as pain, swelling, and redness. Image findings must be analyzed with attention to the specific features such as lesion location, margination, zone of transition, mineralization, size and multifocality, soft tissue component and/or loco-regional extent. Read More

Curr Med Imaging 2022 ;18(6):674-683

Department of Radiology, The Third Hospital of Hebei Medical University, 139 Ziqiang Road Shijiazhuang, Hebei Province, 050051, China.

Background: The scapula is a small irregular-shaped flat bone, which may suffer from a variety of tumors or tumor-like lesions. As the imaging manifestations are complex and changeable, correct imaging diagnosis is difficult.

Introduction: At present, there are few related radiology literatures, and it is necessary to fully analyze the imaging signs of different types of benign and malignant tumors in scapula to guide clinical treatment. Read More

Virchows Arch 2021 Dec 30;479(6):1255-1261. Epub 2021 Aug 30.

Department of Cultural Heritage, University of Bologna, Ravenna, Italy.

Giant cell tumor (GCT) of the bone is a locally aggressive and rarely metastasizing neoplasm. It is composed of neoplastic mononuclear stromal cells with a monotonous appearance admixed with macrophages and osteoclast-like giant cells. In a small subset of cases, GCT is malignant. Read More

Pol J Radiol 2021 5;86:e401-e414. Epub 2021 Jul 5.

The Royal Orthopedic Hospital, United Kingdom.

Purpose: Greater trochanter (GT) lesions are relatively uncommon. They can be traumatic, infective including tuber-culosis, inflammatory, and neoplastic (primary and metastatic osseous lesions). Although imaging of greater trochanter lesions remains essential for differential diagnoses, an image-guided biopsy is a mainstay for diagnosis and to guide subsequent management. Read More

Insights Imaging 2021 Jul 27;12(1):106. Epub 2021 Jul 27.

Department of Interventional Radiology, Hospital Clínic Barcelona, Barcelona, Spain.

Background: To review the safety and efficacy of percutaneous cryoablation for the treatment of chondroblastoma and osteoblastoma in the pediatric and adolescent population.

Materials And Methods: A retrospective review from 2016 to 2020 was performed to evaluate clinical and imaging response to percutaneous cryoablation in 11 symptomatic patients with diagnosis of chondroblastoma and osteoblastoma treated from two pediatric hospitals with at least 12-month follow-up. Technical success (correct needle placement and potential full coverage of the tumor with the planned ablation zone) and clinical success (relief of the symptoms) were evaluated. Read More

World J Clin Cases 2021 Jul;9(20):5709-5716

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha 410011, Hunan Province, China.

Background: Chondroblastoma (CB) is an intermediate tumor of cartilage origin. CB involving the sacrum is a very rare pathology.

Case Summary: A 17-year-old male with sacral CB was diagnosed as CB during the first surgery, and 18 mo later, the tumor recurred and a second surgery was performed with the same pathology result of CB. Read More

Unfallchirurg 2021 Sep 8;124(9):738-746. Epub 2021 Jul 8.

Klinik für Tumororthopädie, Universitätsmedizin Essen, Essen, Deutschland.

Introduction: Conventional chondrosarcoma is the second most common primary malignant bone tumor and usually occurs at older adult ages. It is rare in childhood and adolescence.

Case History: This case report presents the treatment course of a 13-year-old boy with a symptomatic chondrogenic tumor of the right distal femur. Read More

J Cardiothorac Surg 2021 Jul 7;16(1):192. Epub 2021 Jul 7.

Department of Cardiothoracic Surgery, the Third Affiliated Hospital of Sun Yat-Sen University, No.600 Tianhe Road, Guangzhou, China.

Introduction: Chondroblastoma is a rare, benign locally but aggressive bone tumor. It accounts for < 1% of primary bony tumors, and mostly arises from long bones; the rib chondroblastoma is especial rare. Due to its rarity, there are no definitive or standard treatment guidelines. Read More

J Orthop Case Rep 2021 ;11(1):67-71

Department of Orthopaedics, Apollo Speciality Hospitals, Ayanambakkam, Chennai, Tamil Nadu, India.

Introduction: Chondroblastoma is a rare benign cartilaginous neoplasm arising in the epiphysis of long bones in young patients. It is an uncommon benign but locally aggressive tumor, mostly located in the secondary centers of ossification. These tumors arise near a joint or growth plate and surgical excision is always challenging. Read More

BMC Musculoskelet Disord 2021 Jun 16;22(1):549. Epub 2021 Jun 16.

Musculoskeletal Tumor Center, Peking University People's Hospital, Beijing, 100044, China.

Background And Objectives: Treatment of benign osteolytic lesions in the femoral head and neck can be extremely challenging, particularly in children with open physis or for aggressive tumors with pathological fracture. There remains the difficult management decision as to whether to perform complete excision of the involved area or only curettage. Moreover, there is no agreed consensus on the optimal approach to lesion access when performing curettage, which included the transcervical, open and direct approach. Read More

World J Surg Oncol 2021 06 12;19(1):172. Epub 2021 Jun 12.

Department of Orthopaedic Surgery, Kodama Hospital, 1-3-2 Gotenyama, Takarazuka, Hyougo, 665-0841, Japan.

World J Surg Oncol 2021 Jun 12;19(1):171. Epub 2021 Jun 12.

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, 139 Renminzhong Road, Changsha, 410011, Hunan, China.

The purpose of this letter to the Editor is to report some shortcomings in the statistical analysis and variable grouping in the recent publication of the article "Clinical outcomes of chondroblastoma treated using synthetic bone substitute: risk factors for developing radiographic joint degeneration," and to further explore some of the factors that may affect the clinical prognosis of chondroblastoma patients. We also suggest future prospective controlled studies with large samples to improve the limitations encountered by Outani et al. (World J Surg Oncol. Read More

JBJS Case Connect 2021 05 17;11(2). Epub 2021 May 17.

Department of Orthopaedic Surgery, Duke University Medical Center, Durham, North Carolina.

Case: A 15-year-old boy with chondroblastoma of the right hemipelvis presented with significant periacetabular bone destruction. Neoadjuvant denosumab treatment facilitated initial joint preserving surgery. Unfortunately, he experienced 2 local recurrences and underwent wide surgical resection 2 years after his initial diagnosis. Read More

Histopathology 2021 Nov 21;79(5):720-730. Epub 2021 Jul 21.

Bone Tumour Reference Centre at the Institute of Pathology, University Hospital Basel, Basel, Switzerland.

Aims: Giant cell tumour of bone (GCTB) is histologically defined as a lesion containing reactive giant cells and a neoplastic mononuclear cell population; in up to 92% of cases, GCTB is characterised by a specific mutation of the histone gene H3F3A. The cellular composition ranges from giant-cell-rich to giant-cell-poor. The diagnosis of GCTB can be challenging, and several other lesions need to be excluded, e. Read More

BMC Musculoskelet Disord 2021 Apr 23;22(1):381. Epub 2021 Apr 23.

Ningxia Medical University, 1160 Shengli Street, Xingqing District, Yinchuan, 750004, People's Republic of China.

Background: Chondroblastoma (CB) is a rare, primary, benign bone tumor that commonly affects men aged 15-20 years. It is usually detected in the epiphysis of the long bones, such as the proximal femur, humerus, and tibia. The patella is an infrequent site. Read More

Semin Ultrasound CT MR 2021 Apr 29;42(2):123-133. Epub 2020 Aug 29.

Department of Musculoskeletal Imaging, The University of Texas MD Anderson Cancer Center, Houston, TX.

Recent scholarship on enchondroma, chondrosarcoma, and chondroblastoma is presented. The focus of this article is on the imaging appearance of these tumors and the means by which they can be distinguished from one another by both clinical and imaging criteria. Read More

Cureus 2021 Feb 26;13(2):e13565. Epub 2021 Feb 26.

Medical Sciences, Keele University, Keele, GBR.

Background Bone tumours of the talus are a rare cause of ankle pain. This study aims to provide additional clinical clarity regarding the presentation and management of a minimally researched topic. Methods Sixteen patients were diagnosed with bone tumour of the talus between 2002 and 2020 following referral for ankle pain. Read More

World Neurosurg 2021 04;148:236

Division of Neurosurgery, Department of Neurosciences, College of Medicine and Philippine General Hospital, University of the Philippines Manila, Manila, Philippines. Electronic address:

World Neurosurg 2021 04;148:235

Department of Spine Surgery, The Second Xiangya Hospital, Central South University, Changsha, China. Electronic address:

Clin Podiatr Med Surg 2021 Apr 26;38(2):227-233. Epub 2021 Jan 26.

The Iowa Clinic, 5950 University Avenue West, Des Moines, IA 50266, USA; Unitypoint Health - Iowa Methodist Medical Center, 1415 Woodland Avenue, Des Moines, IA 50309, USA.

Bone tumors of the foot are an uncommon finding. Most tumors are found incidentally on imaging and are benign. Care must be taken although due to the aggressive nature of malignant bone tumors that can occur in the calcaneus. Read More

BMJ Case Rep 2021 Feb 26;14(2). Epub 2021 Feb 26.

Otolaryngology, Central Manchester University Hospitals NHS Foundation Trust, Manchester, Greater Manchester, UK.

Chondroblastomas are rare, benign cartilage-producing primary bone tumours that account for 1% of all primary bone tumours. They are usually seen in young adult males and affect long tubulous bones such as the femur or humerus. Occurrences in non-tubular flat bones such as the craniofacial skeleton do occur but are seen in older adults. Read More