1,562 results match your criteria Cholesterol Embolism
Ann Vasc Surg 2018 Jun 5. Epub 2018 Jun 5.
Department of Surgery and Clinical Science, Division of Vascular Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi, Japan.
Background: Although iodinated contrast (IC) agents are commonly used in endovascular aneurysm repair (EVAR), perioperative use in patients with renal dysfunction or IC allergies is avoided. Carbon dioxide (CO)-guided angiography is a promising alternative. We aimed to evaluate short-term and midterm outcomes of EVAR using CO-guided angiography. Read More
Surg Case Rep 2018 Apr 4;4(1):29. Epub 2018 Apr 4.
Department of Surgical Oncology, Faculty of Medicine, University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-8655, Japan.
Background: Cholesterol crystal embolism (CCE) is caused by small crystals of cholesterol dispersed from atherosclerotic plaques of the aorta. There is an increasing interest in CCE because of the increased use of endovascular treatments. Here, we report a rare case of intestinal stenosis caused by CCE after functional end-to-end anastomosis (FEEA). Read More
Mayo Clin Proc 2018 May 24;93(5):597-606. Epub 2018 Mar 24.
Division of Pulmonary and Critical Care Medicine, Rochester, MN; INSERM UMR1227, Lymphocytes B et Autoimmunité, Université de Bretagne Occidentale, CHU de Brest, Brest, France.
Objective: To assess the cardiovascular disease (CVD) and venous thromboembolism (VTE) risks among patients with newly diagnosed antineutrophil cytoplasmic antibodies (ANCA)-associated vasculitis (AAV).
Patients And Methods: A population-based incident AAV cohort of 58 patients diagnosed between 1996 and 2015 in Olmsted County, MN, was identified by medical record review. For each patient, 3 age- and sex-matched non-AAV comparators were randomly selected from the same population and assigned an index date corresponding to the AAV incidence date. Read More
Indian J Pathol Microbiol 2018 Jan-Mar;61(1):116-119
Department of Pathology and Laboratory Medicine, Military Hospital, Jalandhar, Punjab, India.
A 43-year-old apparently healthy male presented with fever and presyncope. He was suspected to have massive pulmonary thromboembolism based on the clinico-biochemical profile. Despite aggressive thrombolytic therapy, he succumbed to his illness within 12 h of admission. Read More
Diabetes Res Clin Pract 2018 Apr 16;138:220-228. Epub 2018 Feb 16.
School of Medicine, College of Medicine, China Medical University, Taichung, Taiwan; Department of Family Medicine, China Medical University Hospital, Taichung, Taiwan. Electronic address:
Aims: A risk scoring system for predicting ischemic stroke incidence may identify type 2 diabetes patients at high risk for ischemic stroke who can benefit from preventive intervention programs. Such a risk scoring system can serve as a benchmark to test novel putative risk factors.
Methods: The study adopted a retrospective cohort, including 28,124 Chinese patients with type 2 diabetes aged 30-84 years during 2001-2004. Read More
Cardiovasc Interv Ther 2018 Jan 5. Epub 2018 Jan 5.
Department of Cardiology, Tokai University School of Medicine, 143 Shimokasuya, Isehara, Kanagawa, Japan.
We previously reported safety and usefulness of transradial iliac artery stenting using 6 Fr guiding sheath. However, radial artery occlusion was a major limitation of this procedure. We analyzed the safety and utility of slender transradial iliac artery stenting using a 4. Read More
J Stroke Cerebrovasc Dis 2018 Mar 2;27(3):764-770. Epub 2017 Nov 2.
Department of Neurosurgery, Hyogo Brain and Heart Center, Himeji City, Hyogo, Japan.
Background: New ischemic lesions on diffusion-weighted imaging (DWI) are frequently found after carotid artery stenting (CAS) and sometimes cause neurologic deficit. We investigated the rate and the potential factor of new DWI lesions during the perioperative period of CAS in symptomatic patients at our institution.
Materials And Methods: Of 187 consecutive patients who underwent CAS (April 2013-August 2016), we investigated 60 symptomatic patients with artery-to-artery embolism from carotid plaque. Read More
Europace 2017 Aug 9. Epub 2017 Aug 9.
Faculty of Medicine, School of Health Sciences, University of Iceland, Vatnsmyrarvegur 16, 101 Reykjavik, Iceland.
Aims: Atrial fibrillation (AF) has been associated with cognitive impairment. Additionally, brain volume may be reduced in individuals with AF. Potential causes may include cerebral micro-embolism or reduced stroke volume due to the beat-to-beat variation in AF. Read More
Intern Med 2018 Jan 25;57(1):71-74. Epub 2017 Sep 25.
Department of Medicine and Clinical Science, Graduate School of Medical Sciences, Kyushu University, Japan.
An 80-year-old man presented at our hospital with renal failure. He had been treated with edoxaban, an oral direct factor Xa inhibitor, for deep vein thrombosis for 10 months prior to admission. Although the pulses in his bilateral pedal arteries were palpable, cyanosis was present in the bilateral toes. Read More
BMJ Case Rep 2017 Sep 21;2017. Epub 2017 Sep 21.
Department of Critical Care Medicine, Centro Policlinico Valencia "La Viña", Valencia, Venezuela.
EJVES Short Rep 2017 4;35:11-15. Epub 2017 Apr 4.
Department of Vascular and Endovascular Surgery, Sir Charles Gairdner Hospital, Nedlands, Perth, WA, Australia.
Introduction: Endovascular aneurysm repair (EVAR) is the most commonly used approach for treatment of abdominal aortic aneurysms (AAA). Testicular infarction is a rare complication of EVAR. A novel case of acute global testicular infarction post-EVAR from cholesterol embolisation mimicking torsion is presented. Read More
Intern Med 2017 09 21;56(18):2531-2533. Epub 2017 Aug 21.
Department of Nephrology, Toyohashi Municipal Hospital, Japan.
Thromb Res 2017 Oct 10;158:49-58. Epub 2017 Aug 10.
Department of Pharmacy Practice and Science, University of Kentucky College of Pharmacy, Lexington, KY, USA; Department of Pharmaceutical Outcomes and Policy, University of Florida College of Pharmacy, Gainesville, FL, USA. Electronic address:
Background: Statins have been shown to have a protective effect for venous thromboembolism (VTE) in the general population. This study sought to assess the association between statins and the risk for cancer-associated deep vein thrombosis (DVT) and pulmonary embolism (PE).
Methods: Patients with newly diagnosed cancer were followed for up to one year in a healthcare claims database (2010-2013). Read More
Nihon Shokakibyo Gakkai Zasshi 2017;114(8):1436-1445
Department of Histopathology and Cytology, Kyoto Second Red Cross Hospital.
A 78-year-old man with hypertension, nephrosclerosis, and angina pectoris visited his family doctor with a history of fatigue and leg edema. He had a history of percutaneous coronary intervention 5 years prior, and was taking low-dose aspirin. Blood tests revealed hypoalbuminemia, gastrointestinal Tc-HSA scintigraphy was positive, and alpha-1 antitrypsin clearance was high;therefore, the hypoalbuminemia was thought to be secondary to a protein-losing enteropathy. Read More
Clin Biochem 2017 Dec 29;50(18):1020-1024. Epub 2017 Jul 29.
Ankara Ataturk Training and Research Hospital, Department of Clinical Biochemistry, Turkey.
BMC Cardiovasc Disord 2017 07 4;17(1):179. Epub 2017 Jul 4.
Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, 465 Kajii-cho, Kawaramachi-Hirokoji, Kamigyo-ku, Kyoto, 602-8566, Japan.
Background: Plaque shifting is a serious complication of endovascular treatment (EVT) for aortoiliac bifurcation lesions. It is challenging to predict the occurrence of unfavorable plaque shifting correctly.
Case Presentation: We report the case of an 88-year-old Japanese woman who experienced constant pain at rest in her left leg. Read More
BMC Nephrol 2017 Jun 7;18(1):187. Epub 2017 Jun 7.
Maisonneuve-Rosemont Hospital Research Center, Montreal, Canada.
Background: Low molecular weight heparins (LMWH) have been extensively studied and became the treatment of choice for several indications including pulmonary embolism. While their efficacy in hemodialysis is considered similar to unfractionated heparin (UFH), their safety remains controversial mainly due to a risk of bioaccumulation in patients with renal impairment. The aim of this systematic review was to evaluate the safety of LMWH when compared to UFH for extracorporeal circuit (ECC) anticoagulation. Read More
Int J Mol Sci 2017 May 24;18(6). Epub 2017 May 24.
Division of Nephrology, Tongji University School of Medicine, Shanghai 200120, China.
Renal disease caused by cholesterol crystal embolism (CCE) occurs when cholesterol crystals become lodged in small renal arteries after small pieces of atheromatous plaques break off from the aorta or renal arteries and shower the downstream vascular bed. CCE is a multisystemic disease but kidneys are particularly vulnerable to atheroembolic disease, which can cause an acute, subacute, or chronic decline in renal function. This life-threatening disease may be underdiagnosed and overlooked as a cause of chronic kidney disease (CKD) among patients with advanced atherosclerosis. Read More
Clin Med Insights Case Rep 2017 17;10:1179547616684649. Epub 2017 Feb 17.
Division of Nephrology, Department of Internal Medicine, Jichi Medical University, Shimotsuke-Shi, Japan.
The avoidance of any form of anticoagulation is advised in cases of cholesterol embolization syndrome (CES). We herein describe a case of CES in a man with a history of unprovoked pulmonary embolism for which warfarinization was performed. Despite anecdotal reports of successful anticoagulation in CES patients with certain indications, irreversible renal failure, which was sufficiently severe to require chronic hemodialysis, eventually developed in our patient. Read More
Dtsch Arztebl Int 2017 Apr;114(14):251
J Stroke Cerebrovasc Dis 2017 Aug 13;26(8):1670-1677. Epub 2017 Apr 13.
Department of Neurology, University Hospital Donostia, San Sebastián, Spain; Faculty of Medicine, University of the Basque Country, Leioa, Spain.
Objective: The aims of this study are, first, to calculate the risk of brain ischemia recurrence and embolic source diagnosis in the follow-up of patients with ESUS (embolic stroke of undetermined source) and, second, to identify the predictors of these events including cardiologic, laboratory, and clinical factors.
Methods: A retrospective observational cohort study of stroke patients admitted to the stroke unit in a single tertiary hospital from 2012 to 2014 was performed. Patients fulfilling ESUS criteria were identified and followed by medical history review until March 2016. Read More
Best Pract Res Clin Gastroenterol 2017 Feb 28;31(1):105-109. Epub 2016 Jul 28.
Department of Vascular Diseases, Skåne University Hospital, 2-205 02 Malmö, Sweden. Electronic address:
Visceral arteries such as the coeliac (CA), superior mesenteric (SMA), and the inferior mesenteric artery (IMA) might be affected by atherosclerotic occlusive lesions with or without thrombosis or embolization causing ischaemic symptoms from the gastrointestinal tract. After treatment of an acute event, these patients should be offered both non-pharmacological and pharmacological secondary prevention to reduce risk for future ischaemic arterial manifestations. Patients with mesenteric ischaemia caused by atherosclerosis should be evaluated concerning platelet antiaggregation with low dose aspirin or clopidogrel, and those with cardioembolic disease should be recommended anticoagulant treatment with either warfarin or one of the direct oral anticoagulants (DOAC; apixaban, dabigatran, edoxaban, or rivaroxaban). Read More
J Thromb Haemost 2017 04 25;15(4):695-701. Epub 2017 Feb 25.
Department of Clinical Epidemiology, Leiden University Medical Center, Leiden, the Netherlands.
Essentials The role of lipid levels in the risk of recurrent venous thrombosis is unclear. Lipids were assessed in patients with a first venous thrombosis (n = 2106) followed for 6.9 years. Read More
Przegl Lek 2017;74(2):53-6
Background: Pulmonary embolism is a clinical manifestation of venous thromboembolism (VTE), also comprising deep vein thrombosis. It is considered to be a consequence of environmental and genetic factors. The number of predisposing risk factors is high. Read More
Cardiovasc Interv Ther 2017 Oct 9;32(4):401-404. Epub 2016 Nov 9.
Department of Cardiology, Heart Center, St. Luke's International Hospital, 5-12-3 Akashichou, Chuou-ku, Tokyo, 106-0085, Japan.
In daily practice, the iatrogenic complication hydrophilic polymer embolization (HPE) is under-recognized. An 86-year-old male experienced a distal foot embolization after transcatheter aortic valve replacement. Rashes appeared only in the access side foot just after the procedure. Read More
Cutis 2016 Sep;98(3):E8-E10
Department of Dermatology, Kurume University School of Medicine, Japan.
Heart Vessels 2016 Nov 5;31(11):1886-1888. Epub 2016 Mar 5.
Department of Cardiovascular Medicine, National Cerebral and Cardiovascular Center, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.
Subclavian artery stenosis can cause a flow reversal-so-called steal-not only in the ipsilateral vertebral artery, but also in the internal mammary artery in patients with a history of coronary-artery bypass grafting. Subclavian artery stenosis is also associated with peripheral artery disease elsewhere. We report a novel finding of axillo-femoral bypass steal due to subclavian artery stenosis identified by vascular ultrasonography. Read More
Med Intensiva 2018 05 25;42(4):e4. Epub 2016 Oct 25.
Unidad de Cuidados Intensivos, Hospital Universitario Reina Sofía, Córdoba, España.
J Am Heart Assoc 2016 Oct 20;5(10). Epub 2016 Oct 20.
Center for Healthcare Advancement and Outcomes, Baptist Health South Florida, Miami, FL Miami Cardiac & Vascular Institute, Baptist Health South Florida, Miami, FL Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL Department of Medicine, Herbert Wertheim College of Medicine, Florida International University, Miami, FL Ciccarone Center for the Prevention of Heart Disease, Johns Hopkins University, Baltimore, MD
Background: The American Heart Association introduced the Life's Simple 7 (LS7) metrics to assess and promote cardiovascular health. We examined the association between the LS7 metrics and noncardiovascular disease.
Methods And Results: We studied 6506 men and women aged between 45 and 84 years, enrolled in the Multi-Ethnic Study of Atherosclerosis. Read More
Neth J Med 2016 Oct;74(8):365
Department of Internal Medicine, Rijnstate Hospital, Arnhem, the Netherlands.
N Engl J Med 2016 Sep;375(11):e25
Bichat Hospital, Paris, France
Invest Ophthalmol Vis Sci 2016 09;57(11):4589-98
Department of Ophthalmology Seoul National University College of Medicine, Seoul National University Bundang Hospital, Seongnam, South Korea.
Purpose: To analyze the characteristics of retinal emboli and their association with vascular reperfusion in retinal artery occlusion (RAO).
Methods: In this retrospective comparative case series, we analyzed emboli in patients with acute central retinal artery occlusion (CRAO) or branch retinal artery occlusion (BRAO) and visible emboli, and analyzed vascular reperfusion in patients with visible emboli causing blockage of perfusion. The patients were divided into emboli "movement" and "no movement" groups and their vascular reperfusion states were compared. Read More
Clin Appl Thromb Hemost 2017 Nov 24;23(8):973-979. Epub 2016 Sep 24.
2 The Cholesterol, Metabolism, and Thrombosis Center, Cincinnati, OH, USA.
We compared thrombophilia and hypofibrinolysis in 6 men with Klinefelter syndrome (KS), without previously known familial thrombophilia, who had sustained deep venous thrombosis (DVT)-pulmonary emboli (PE) or mesenteric artery thrombosis on testosterone replacement therapy (TRT). After the diagnosis of KS, TRT had been started in the 6 men at ages 11, 12, 13, 13, 19, and 48 years. After starting TRT, DVT-PE or mesenteric artery thrombosis was developed in 6 months, 1, 11, 11, 12, and 49 years. Read More
Folia Med (Plovdiv) 2016 Apr-Jun;58(2):77-88
Department of Propedeutics of Internal Medicine, Faculty of Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria
Micro- and macrovascular pathology is a frequent finding in a number of common rheumatic diseases. Secondary Raynaud's phenomenon (RP) is among the most common symptoms in systemic sclerosis and several other systemic autoimmune diseases including a broad differential diagnosis. It should be also differential from other peripheral vascular syndromes such as embolism, thrombosis, etc. Read More
Medicine (Baltimore) 2016 Aug;95(32):e4495
aEmergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing Institute of Heart, Lung and Blood Vascular Disease, Beijing, China bDepartment of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Background: Previous studies have shown that idiopathic pulmonary embolism is positively associated with other cardiovascular events, such as myocardial infarction and stroke, suggesting a potentially important association between atherosclerosis risk factors and venous thromboembolism (VTE). We performed a meta-analysis to evaluate the correlation between risk factors for atherosclerosis and VTE.
Methods: In December 2014, we searched MEDLINE and EMBASE for studies evaluating the associations between VTE and risk factors for atherosclerosis and pooled outcome data using random-effects meta-analysis. Read More
Exp Ther Med 2016 Aug 17;12(2):1012-1018. Epub 2016 May 17.
Department of Nephrology, The First Affiliated Hospital of Xiamen University, Xiamen, Fujian 361003, P.R. China.
Cholesterol embolism is a multisystemic disorder with clinical manifestations that resemble vasculitis. Anti-neutrophil cytoplasmic antibodies (ANCA) are a defining feature of ANCA-associated vasculitis, and the presence of ANCA in cholesterol embolism complicates its differential diagnosis and treatment. At present, the role of ANCA in cholesterol embolism remains unclear and no effective treatment is currently available. Read More
Respir Res 2016 07 19;17(1):86. Epub 2016 Jul 19.
Department of Emergency Medicine and Department of Cellular and Integrative Physiology, Indiana University Medical School, 720 Eskanazi Avenue, Indianapolis, IN, 46202, USA.
Background: Pulmonary thromboembolism (PTE) is a common diagnosis and a leading cause of cardiovascular morbidity and mortality. A growing literature has associated PE with systemic inflammation, and global hyper-coagulability, which contribute to lung remodeling and clot recurrence. The source and mechanism of inflammation remains unstudied. Read More
Int J Cardiol 2016 Oct 23;220:284-9. Epub 2016 Jun 23.
Department of Cardiology, Beijing Anzhen Hospital, Capital Medical University, National Clinical Research Centre for Cardiovascular Diseases, Beijing, China. Electronic address:
Background: Atrial fibrillation (AF) is associated with increased incidence of cardiovascular disease, and hence, statin therapy is indicated in majority of AF patients.
Methods And Results: We analyzed data from the Chinese Atrial Fibrillation Registry (CAFR) involving 11,496 AF patients from 2011 to 2014. Practice patterns of statin therapy and factors associated with statin underuse were analyzed. Read More
Gastroenterology 2016 Aug 1;151(2):243-4. Epub 2016 Jul 1.
Internal Medicine Unit, Istituti Ospitalieri di Cremona, Cremona, Italy.
Nephrology (Carlton) 2016 Jul;21(7):631
Manly Hospital, Sydney, New South Wales, Australia.
Pol Merkur Lekarski 2016 May;40(239):283-7
Medical University of Lodz, Poland: Department of Pharmacology and Toxicology.
Unlabelled: Pulmonary embolism (PE) usually is a clinical manifestation of venous thromboembolism. The lack of simple and safe laboratory test to confirm or exclude PE is a problem that slows down the diagnosis.
Aim: The aim of the study was the assessment the usefulness of D-dimer and HDL cholesterol concentration in predicting the occurrence of acute pulmonary embolism. Read More
Rinsho Byori 2016 Jan;64(1):66-71
Along with the established evidence on the association between a low HDL cholesterol level and arterial thrombosis, several limited studies have suggested that low HDL cholesterol is also a risk factor for venous thrombosis, such as deep vein thrombosis and pulmonary embolism. As well as emerging evidence from clinical studies, basic research has proposed the interaction between HDL and key molecules in the field of thrombosis and hemostasis; HDL interacts with megakaryocytes to affect the production of platelets, suppresses the aggregation of platelets, protects against the injury of endothelial cells, and inhibits coagulation and fibrinolysis cascades. Considering these reports together, HDL can possess anti-thrombotic properties as one of its pleiotropic effects other than its role in the reverse transport system of cholesterol. Read More
Nihon Shokakibyo Gakkai Zasshi 2016 05;113(5):804-12
Department of Gastrointestinal and Hepato-Biliary-Pancreatic Surgery, Nippon Medical School.
We report a case of jejunal perforation related to cholesterol crystal embolism (CCE) in a woman in her seventies. The jejunum was partially resected;histological examination of the resected tissue revealed that the perforation was caused by CCE. On postoperative day 12, computed tomography (CT) showed free air in the abdomen. Read More
Turk Kardiyol Dern Ars 2016 Apr;44(3):251-5
Department of Internal Medicine and Nephrology, İstanbul Medeniyet University, Göztepe Training and Research Hospital, İstanbul, Turkey.
Cholesterol embolization syndrome (CES) is a multisystemic disease with immunological features, and a rare but an important cause of acute kidney injury (AKI) following invasive angiography. It frequently occurs in the elderly male population with extensive atherosclerosis. CES should be considered in the differential diagnosis of AKI following angiography, as prognosis and treatment are completely different from contrast-induced nephropathy. Read More
Nihon Naika Gakkai Zasshi 2016 May;105(5):850-856
Clin Exp Nephrol 2017 Apr 21;21(2):228-235. Epub 2016 Apr 21.
Department of Nephrology, Japan Community Health Care Organization Sendai Hospital, 3-16-1 Tsutsumimachi, Aoba-ku, Sendai, Miyagi, 981-8501, Japan.
Background: Corticosteroids have been widely used in patients with cholesterol crystal embolism (CCE) and low-density lipoprotein apheresis (LDL-A) was reported to reduce the risk of end-stage renal disease in patients with CCE. This study was designed to evaluate the renoprotective effects of LDL-A in combination with corticosteroids in patients with CCE.
Methods: Thirty-five patients with CCE who, between 2008 and 2013, had shown renal deterioration after vascular interventions were retrospectively evaluated. Read More
Int J Surg Case Rep 2016 13;23:89-92. Epub 2016 Apr 13.
Department of Pathology, Haukeland University Hospital, Jonas Lies vei 65, 5021 Bergen, Norway; The Gade Laboratory for Pathology, Department of Clinical Medicine, University of Bergen, Haukeland University Hospital, 5021 Bergen, Norway. Electronic address:
Introduction: When ischemic events ascribable to microembolization occur during open repair of proximal abdominal aortic aneurysms, a likely origin of atheroembolism is not always found.
Presentation Of Case: A 78-year old man with enlargement of the entire aorta underwent open repair for a pararenal abdominal aortic aneurysm using supraceliac aortic clamping for 20min. Then the graft was clamped, the supraceliac clamp was removed, and the distal and right renal anastomoses were also completed. Read More
J Thromb Haemost 2016 06 10;14(6):1183-91. Epub 2016 May 10.
K. G. Jebsen Thrombosis Research and Expertise Center (TREC), Department of Clinical Medicine, University of Tromsø-The Arctic University of Norway, Tromsø, Norway.
Unlabelled: Essentials Registry-based studies indicate a link between arterial- and venous thromboembolism (VTE). We studied this association in a cohort with confounder information and validated outcomes. Myocardial infarction (MI) was associated with a 4. Read More
JAMA 2016 Apr;315(13):1396-7
Department of Dermatology and Pathology, University of Iowa Hospitals and Clinics, Iowa City.
World J Gastroenterol 2016 Mar;22(12):3502-5
Shunjiro Azuma, Maiko Ikenouchi, Takuji Akamatsu, Takeshi Seta, Shunji Urai, Yoshito Uenoyama, Yukitaka Yamashita, Department of Gastroenterology, Japan Red Cross Society Wakayama Medical Center, Wakayama-city, Wakayama 640-8558, Japan.
Cholesterol crystal embolization (CCE) is a rare systemic embolism caused by formation of cholesterol crystals from atherosclerotic plaques. CCE usually occurs during vascular manipulation, such as vascular surgery or endovascular catheter manipulation, or due to anticoagulation or thrombolytic therapy. We report a rare case of intestinal obstruction caused by spontaneous CCE. Read More