1,655 results match your criteria Cholesterol Embolism


Delayed Onset of Retinal Embolism After Coronary Angioplasty.

J Invasive Cardiol 2021 Jun 6;33(6):E483. Epub 2021 May 6.

Servicio de Oftalmología, Hospital Clínico San Carlos, Calle profesor Martín Lagos s/n, Madrid, 28040, Spain.

Although rare, retinal artery cholesterol emboli (Hollenhorst plaques) post angioplasty can be a severe event that can cause irreversible visual disturbances, usually taking place during or following the procedure. However, as the number of procedures continues to increase, interventional radiologists or cardiologists who perform coronary catheterization should be cognizant of its possible delayed occurrence, as in the case presented herein. Read More

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Cutaneous Polymer-Coating Embolism After Endovascular Procedures: Report of Two Cases and a Literature Review.

Am J Dermatopathol 2021 Feb 16. Epub 2021 Feb 16.

Departments of Pathology; Cardiology, and Dermatology, Clinical University Hospital, Santiago de Compostela, Spain; and Departments of Dermatology, and Forensic Sciences and Pathology, Faculty of Medicine, University of Santiago de Compostela.

Abstract: Different hydrophilic and hydrophobic polymers are used as lubricious coatings to reduce vascular traumas in minimally invasive percutaneous procedures. Although they are usually very safe, there is still a risk of serious complications in patients undergoing such procedures, mostly derived from the devices' coating detachment and systemic embolization. The lungs are the most common organ involved, followed by the central nervous system. Read More

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February 2021

Ischemic small bowel perforation caused by cholesterol crystal embolism following transcatheter arterial chemoembolization for recurrent hepatocellular carcinoma: a case report.

Surg Case Rep 2021 Feb 10;7(1):45. Epub 2021 Feb 10.

Department of Surgery, The Jikei University School of Medicine, 3-25-8, Nishi-Shinbashi, Minato-ku, Tokyo, 105-8461, Japan.

Background: Cholesterol crystal embolism (CCE) following transcatheter arterial chemoembolization (TACE) is rare.

Case Presentation: A 71-year-old man underwent TACE for recurrence of hepatocellular carcinoma (HCC). On postoperative day (POD) 5, he developed abdominal pain and fever. Read More

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February 2021

Ischemic stroke and retinal artery occlusion after carotid aneurysm embolization.

Radiol Case Rep 2021 Mar 9;16(3):701-703. Epub 2021 Jan 9.

Hôpital Fondation Adolphe de Rothschild, 25, rue Manin, 75019 Paris, France.

We present the case of a 72-year-old male with a right carotid aneurysm incidentally discovered after an ischemic stroke. After management of the stroke, stent-assisted coil embolization was performed to treat the aneurysm. Two simultaneous and early complications occurred: new ischemic strokes and branch retinal artery occlusions, respectively in the right occipital lobe and in the right eye. Read More

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Spontaneous Cholesterol Crystal Embolism and Aortic Plaques.

Intern Med 2021 Jun 15;60(12):1981-1982. Epub 2021 Jan 15.

Division of Internal Medicine, Mitsui Memorial Hospital, Japan.

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Crystalopathy - underestimated entity in nephrology.

Vnitr Lek 2020 ;66(6):371-377

Crystal is a solid particle with a geometric shape because its atoms, ions, or molecules are arranged in a regular ordered structure. However, in case of accidental order of the particles, we are talking about the amorphous substances which can also form crystallike particles. Crystallopathy is a disease that involves crystals of crystallike particulate matter in the pathogenesis of tissue injury. Read More

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January 2021

The significance of Holter electrocardiography in the etiological evaluation of transient ischemic stroke.

Brain Circ 2020 Jul-Sep;6(3):191-195. Epub 2020 Sep 30.

Department of Neurology, Izmir Tepecik Education and Research Hospital, Izmir,, Turkey.

Background: Transient ischemic attack (TIA) is a common neurovascular disorder associated with a higher risk of stroke within the first 24 h after the first event. Acute cerebral and arterial neuroimaging combined with long-term electrocardiography (ECG) monitoring have been proven to be useful in determining etiology. Cardio-embolism constitutes 20%-26% etiology of TIAs most of them with atrial fibrillation (AF). Read More

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September 2020

Durvalumab-associated vasculitis presenting as 'the blue toe syndrome'.

BMJ Case Rep 2020 Nov 18;13(11). Epub 2020 Nov 18.

Internal Medicine, St John of Gods Hospital Midland, Perth, Western Australia, Australia.

Durvalumab is a selective, high-affinity human immunoglobulin monoclonal antibody in a class called check point inhibitors, that blocks PD-L1 on tumour cells. Despite clinical success in increasing progression-free survival rates in patients with stage III non-small-cell lung cancer, durvalumab has been associated with immune-related side effects such as pneumonitis and colitis. We present a case of an 84-year-old woman with acral vasculitis presenting as blue toe syndrome, associated with prolonged use of durvalumab. Read More

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November 2020

Mimics of vasculitis.

Rheumatology (Oxford) 2021 01;60(1):34-47

Division of Rheumatology, University of California, Los Angeles, Los Angeles, CA, USA.

While prompt diagnosis of vasculitis is important, recognition of vasculitis mimics is equally essential. As in the case of vasculitis, an approach to mimics based on the anatomic size of vessels can be useful. Infections can mimic vasculitis of any vessel size, including the formation of aneurysms and induction of ANCAs. Read More

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January 2021

The new prognostic factor for pulmonary embolism: The ratio of monocyte count to HDL cholesterol.

Am J Emerg Med 2020 Jul 16. Epub 2020 Jul 16.

Health Science University, Adana City Research and Training Hospital, Department of Emergency Medicine, Adana, Turkey.

Purpose: Aim of this study is to investigate effectiveness of the monocyte to HDL cholesterol ratio in patients diagnosed with pulmonary embolism for predicting intra-hospital mortality.

Method: A total of 269 patients diagnosed with pulmonary embolism in the emergency clinic were included in the study. Study was conducted retrospectively. Read More

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Angiogenic Dreaded Killer: Cholesterol Crystal Embolization.

Intern Med 2021 Mar 14;60(6):825-826. Epub 2020 Oct 14.

Department of Gastroenterology and Hepatology, Hokkaido University Hospital, Japan.

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An Autopsy Case of Acute Pancreatitis Caused by Cholesterol Crystal Embolization.

Intern Med 2021 Mar 14;60(6):839-845. Epub 2020 Oct 14.

Department of Gastroenterology, Faculty of Medicine, Oita University, Japan.

Cholesterol crystal embolization (CCE) shows a poor prognosis and it can cause ischemic organ damage due to a cholesterol embolism from atherosclerotic lesions in large blood vessels. Such an embolism mainly affects the kidneys and skin, although cases involving digestive organs have also been reported. We encountered an autopsy case of CCE with damage mainly to the digestive organs, including the pancreas. Read More

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Cholesterol embolization and arterial occlusion from the Heimlich maneuver.

Am J Emerg Med 2021 05 30;43:290.e1-290.e3. Epub 2020 Sep 30.

Department of Emergency Medicine, San Antonio Uniformed Services Health Education Consortium, 3551 Roger Brooke Dr, Fort Sam Houston, TX 78234, United States. Electronic address:

The Heimlich maneuver is a lifesaving bystander intervention to assist an individual with airway obstruction however, cholesterol embolization syndrome is a rare, but serious potential complication of the Heimlich maneuver. We present the case of the 56-year-old female presenting to the emergency department with acute right foot pain following performance of the Heimlich maneuver who was found to have distal arterial occlusion resulting from cholesterol embolization syndrome. The patient underwent right popliteal artery exploration, right popliteal and tibial thrombectomy, and popliteal patch angioplasty resulting in restoration of blood flow to her right foot. Read More

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Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China.

JAMA Netw Open 2020 09 1;3(9):e2017507. Epub 2020 Sep 1.

Guangdong Provincial Engineering Technology Research Center of Environmental and Health Risk Assessment, Department of Occupational and Environmental Health, Sun Yat-sen University School of Public Health, Guangzhou, China.

Importance: Living in areas with more vegetation (referred to as residential greenness) may be associated with cardiovascular disease (CVD), but little data are available from low- and middle-income countries. In addition, it remains unclear whether the presence of cardiometabolic disorders modifies or mediates the association between residential greenness and CVD.

Objective: To evaluate the associations between residential greenness, cardiometabolic disorders, and CVD prevalence among adults in China. Read More

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September 2020

A rare case of fatal multi-organ polymer graft material and cholesterol embolization following aortic repair.

Cardiovasc Pathol 2021 Jan - Feb;50:107287. Epub 2020 Sep 13.

Department of Pathology and Laboratory Medicine, East Carolina University/Vidant Medical Center, Greenville, NC, USA.

Ischemia is a common complication of various endovascular procedures including endovascular aortic aneurysm repair. Multiple mechanisms can contribute to the pathogenesis of ischemia: thrombosis, arterial dissection, graft malpositioning, cholesterol embolization, and polymer graft embolization which is an underrecognized complication. To the best of our knowledge, only 38 cases of polymer graft embolization have been reported in the literature. Read More

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December 2020

Cholesterol Crystal in Thrombus Removed by Mechanical Thrombectomy Should be a Strong Marker for Aortogenic Embolic Stroke.

J Stroke Cerebrovasc Dis 2020 Oct 30;29(10):105178. Epub 2020 Jul 30.

Department of Neurological Science, Graduate School of Medicine, Nippon Medical School. Electronic address:

Aortogenic embolic stroke (AES) is an important stroke mechanism. However, as many stroke patients have aortic atheromatous lesions, it is unclear whether these lesions are the cause of these strokes. Cholesterol crystals are the solid, crystalline form of cholesterol that is found in atherosclerosis, but not in cardiac diseases such as atrial fibrillation, valvular diseases, and cardiomyopathy. Read More

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October 2020

[Repeated Hemoptysis after Thoracic Endovascular Aortic Repair for Ruptured Thoracic Aortic Aneurysm with Hemoptysis;Report of a Case].

Kyobu Geka 2020 Sep;73(9):695-699

Department of Cardiovascular Surgery, Kyoto-Katsura Hospital, Kyoto, Japan.

In recent years, re-rupture due to endoleaks after thoracic endovascular aortic repair (TEVAR) for ruptured thoracic aortic aneurysms has become a problem. Hemoptysis has been reported in patients after pneumocentesis. We report a patient who developed delayed hemoptysis not related to endoleak after TEVAR. Read More

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September 2020

Monocyte High Density Lipoprotein Cholesterol Ratio as a New Prognostic Factor for Mesenteric Embolism.

J Coll Physicians Surg Pak 2020 Jul;30(7):688-693

Department of General Surgery, Health Science University, Adana City Research and Training Hospital, Turkey.

Objective: To determine the effectiveness of the ratio of monocyte count to high density lipoprotein cholesterol in predicting in-hospital mortality.

Study Design: Descriptive study.

Place And Duration Of Study: Intensive Care Unite, Adana Numune Research and Training Hospital, Turkey, from January 2018 to December 2019. Read More

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50-year-old man • foot pain • "purple" toe • history of smoking • Dx?

Authors:
Meagan Vermeulen

J Fam Pract 2020 Jul/Aug;69(6):E14-E16

Department of Family Medicine, Rowan University School of Osteopathic Medicine, Stratford, NJ, USA. Email:

► Foot pain ► "Purple" toe ► History of smoking. Read More

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November 2020

Cholesterol Embolization Syndrome From Penetrating Aortic Ulcer.

Cureus 2020 Jun 17;12(6):e8670. Epub 2020 Jun 17.

Internal Medicine, Magnolia Regional Health Center, Corinth, USA.

Penetrating aortic ulcer (PAU) is an important, albeit, rarer cause of embolization to internal organs and distal extremities. Embolization occurs as a result of the disruption of cholesterol deposition in the wall of the aorta by a PAU. The classic presentation of cholesterol embolization syndrome (CES) includes pain, pallor, poikilothermia, paresthesia, and paralysis with intact pulses. Read More

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Cholesterol Embolization Syndrome After Carotid Artery Stenting Associated with Delayed Cerebral Hyperperfusion Intracerebral Hemorrhage.

World Neurosurg 2020 10 15;142:274-282. Epub 2020 Jul 15.

Neuroendovascular Therapy Center, Aichi Medical University, Aichi, Japan; Department of Neurosurgery, Aichi Medical University, Aichi, Japan.

Background: The cholesterol embolization syndrome (CES) results from the distal embolization of cholesterol crystals from atheromatous plaques in large vessels such as the aorta and results in multiorgan damage.

Case Description: We present the case of a patient with definite CES with skin manifestations (e.g. Read More

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October 2020

Cholesterol Emboli Co-Existing with Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis in a 76-Year-Old Woman.

Tohoku J Exp Med 2020 05;251(1):61-68

Department of Nephrology, Shinshu University Hospital.

Anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis injures small vessels and causes severe systemic organ injury. Main target antigens of ANCA are myeloperoxidase and proteinase 3. ANCA strongly associates with the development and progression of the vasculitis. Read More

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Multiple Small Bowel Perforations Associated With Cholesterol Crystal Embolization After Transcatheter Aortic Valve Replacement.

JACC Cardiovasc Interv 2020 08 27;13(15):1831-1832. Epub 2020 May 27.

Department of Cardiovascular Medicine, Graduate School of Medical Science, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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Nontraumatic Multiple-Organ Fat Embolism: An Autopsy Case and Review of Literature.

Am J Forensic Med Pathol 2020 Jun;41(2):131-134

From the School of Forensic Medicine.

The patient was an 88-year-old woman with a 10-year history of hypertension. She was suspected to have been hit by a car. At the time of the event, she was conscious and able to stand on her own and had no obvious injuries. Read More

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F-fluorodeoxyglucose-positron emission tomography/computed tomography for the diagnosis of polymyalgia-like illnesses: a retrospective study.

BMC Rheumatol 2020 24;4:21. Epub 2020 Apr 24.

1Division of Hematology and Rheumatology, Department of Internal Medicine, National Defense Medical College, 3-2 Namiki, Tokorozawa, Saitama, 359-8513 Japan.

Background: Various inflammatory conditions may present with musculoskeletal symptoms similar to those of polymyalgia rheumatica (PMR). We investigated findings on F-fluorodexoxyglucose (FDG)-positron emission tomography/computed tomography (PET/CT) images that may differentiate PMR from polymyalgia-like illnesses.

Methods: We analyzed data from 25 patients with new-onset polymyalgia-like illnesses who fulfilled Bird's diagnostic criteria for PMR and had undergone FDG-PET/CT scan. Read More

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Proportion and risk factors of cholesterol crystal embolization after cardiovascular procedures: a retrospective national database study.

Heart Vessels 2020 Sep 10;35(9):1250-1255. Epub 2020 Apr 10.

Department of Clinical Epidemiology and Health Economics, School of Public Health, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo, 113-0033, Japan.

Cholesterol crystal embolization (CCE) is a rare, mainly iatrogenic condition. The proportion of CCE after cardiovascular procedures has not been fully elucidated. The purpose of this study was to determine the proportion of CCE diagnosed after cardiovascular procedures and to identify risk factors for CCE occurrence. Read More

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September 2020

Association between eosinophilia and renal prognosis in patients with pathologically proven cholesterol crystal embolism.

Clin Exp Nephrol 2020 Aug 7;24(8):680-687. Epub 2020 Apr 7.

Kidney Disease and Transplant Center, Shonan Kamakura General Hospital, 1370-1 Okamoto, Kamakura, Kanagawa, 247-8533, Japan.

Background: Approximately, 20-70% of patients with cholesterol crystal embolism (CCE) have eosinophilia. However, it remains unknown how eosinophilia influences renal prognosis in patients with CCE. In this study, we investigated the association between eosinophil count (Eo) and renal prognosis in CCE patients on steroid therapy. Read More

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Clinical features and prognosis of acute myocardial infarction caused by non-tumor origin coronary artery embolism.

Am J Emerg Med 2020 06 24;38(6):1185-1191. Epub 2020 Mar 24.

Department of Cardiology, The Key Laboratory of Cardiovascular Disease of Wenzhou, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325000, PR China.

Background: Several studies have indicated that acute myocardial infarction (AMI) secondary to coronary artery embolism (CE) has a poor prognosis. However, in the latter studies, CE of tumor origin accounts for a considerable proportion of cases and the clinical features and contribution to overall prognosis of non-tumor CE are unknown and therefore the subject of this study.

Methods: We retrospectively studied 2006 consecutive patients with AMI at our medical center from January 2014 to October 2018. Read More

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Peripheral Artery Disease and Venous Thromboembolic Events After Acute Coronary Syndrome: Role of Lipoprotein(a) and Modification by Alirocumab: Prespecified Analysis of the ODYSSEY OUTCOMES Randomized Clinical Trial.

Circulation 2020 05 29;141(20):1608-1617. Epub 2020 Mar 29.

Brigham and Women's Hospital Heart & Vascular Center and Harvard Medical School, Boston, MA (D.L.B.).

Background: Patients with acute coronary syndrome are at risk for peripheral artery disease (PAD) events and venous thromboembolism (VTE). PCSK9 (proprotein convertase subtilisin/kexin type 9) inhibitors reduce lipoprotein(a) and low-density lipoprotein cholesterol (LDL-C) levels. Our objective was to ascertain whether PCSK9 inhibition reduces the risk of PAD events or VTE after acute coronary syndrome, and if such effects are related to levels of lipoprotein(a) or LDL-C. Read More

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