39,246 results match your criteria Cholelithiasis Imaging

Glucose 6 phosphate dehydrogenase deficiency: A single-center experience.

Turk Arch Pediatr 2021 1;56(3):245-248. Epub 2021 May 1.

Pediatric Hematology and Oncology Clinic, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.

Objective: This study aims to evaluate the demographic information, clinical and laboratory findings of patients with glucose 6 phosphate dehydrogenase deficiency.

Material And Methods: We collected data by reviewing files and electronic records of 65 patients with glucose 6 phosphate dehydrogenase deficiency under the age of 18 years who were followed up in our clinic between 2007 and 2019. Demographic, clinical, and laboratory features, family history, complications of the disease, and history of splenectomy and cholecystectomy were evaluated. Read More

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Role of EGFR and HER-2/NEU Expression in Gall Bladder Carcinoma (GBC).

J Lab Physicians 2021 Mar 19;13(1):29-35. Epub 2021 May 19.

Department of Pediatric Surgery, Apollo Gleneagles Hospital, Kolkata, India.

 Gall bladder carcinoma (GBC) is the most common malignancy of the biliary tract. Being known for its geographical and racial variations, and compared with the global statistics, its incidence is higher in the Indian subcontinent, mainly in the northern and eastern regions, accounting for 80 to 95% of cases.  This study was conducted to evaluate the clinic-pathological spectrum and expression of EGFR and HER-2/NEU in GBCs and to understand their relation to prognosis, paving the way for targeted therapies for better treatment outcomes and patient survival. Read More

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Maternal bile acid profile and subtype analysis of intrahepatic cholestasis of pregnancy.

Orphanet J Rare Dis 2021 Jun 7;16(1):259. Epub 2021 Jun 7.

The Department of Obstetrics and Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.

Background: ICP pregnant women have a unique profile of serum bile acid metabolism, thus the early and accurate identification of ICP patients is beneficial to early appropriate treatment and improvement of pregnancy outcomes. In this study, ultra-high performance liquid chromatography-mass spectrometry/mass spectrometry (UPLC-MS/MS) was used to analyze the 15 types of serum bile acid profiles among patients with ICP in third trimester, patients with cholelithiasis, and patients with hepatitis B virus. The ICP diagnostic model established by partial least squares-discriminant analysis (PLS-DA) was used to screen the differential bile acids for clinical subtypes of ICP. Read More

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Association between metabolic syndrome and incidence of cholelithiasis in the Korean population.

J Gastroenterol Hepatol 2021 Jun 7. Epub 2021 Jun 7.

Departments of Occupational and Environmental Medicine, School of Medicine, Kyung Hee University, Seoul, Korea.

Background And Aim: Cholelithiasis is one of the most common gastrointestinal diseases worldwide. The metabolic syndrome (MetS), a combination of various metabolic abnormalities, is also common with a continually increasing prevalence. These diseases are associated with several risk factors. Read More

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Management of Obscurely Dilated Common Bile Duct with Normal Liver Function Tests: A Pragmatic Approach.

World J Surg 2021 Jun 6. Epub 2021 Jun 6.

Department of Gastrointestinal Surgery, G B Pant Institute of Post Graduate Medical Education and Research, 1, Jawaharlal Nehru Marg, New Delhi, 110002, India.

Objective: Dilated common bile duct (CBD) (8-15 mm) with normal liver function tests is seen not infrequently, while management of such patients is ambiguous. We propose a treatment algorithm for this cohort of patients after observing them over a period of 8 years.

Methods: Seventy-eight such patients were managed from 2009 to 2017 and categorized as: Group A-dilated CBD with post-cholecystectomy status (n = 15); B-dilated CBD with cholelithiasis (n = 34); C-dilated CBD without cholelithiasis (n = 16); D-dilated CBD with no cause identified and underwent CBD excision (n = 13). Read More

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[Management of cholelithiasis in times of COVID-19. A challenge for the system].

Cir Esp 2021 Jun 1. Epub 2021 Jun 1.

Unidad de Cirugía Hepatobiliopancreática, Hospital del Mar, Barcelona. Universidad Pompeu Fabra, Spain.

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Establishment of a nomogram prediction model for long diameter 10-15 mm gallbladder polyps with malignant tendency.

Surgery 2021 Jun 2. Epub 2021 Jun 2.

Department of Hepatobiliary Surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China. Electronic address:

Background: Surgical indications for the treatment of gallbladder polyps are controversial. Evaluation of gallbladder polyps with malignant tendency and indications for cholecystectomy in patients with long diameter polyps of 10 to 15 mm require further analysis and discussion. In this study, our objective was to re-evaluate indications for the surgical resection of gallbladder polyps and construct a nomogram model for the prediction of gallbladder polyps with malignant tendency. Read More

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Laparoscopy in Low-Income Countries: 10-Year Experience and Systematic Literature Review.

Int J Environ Res Public Health 2021 May 28;18(11). Epub 2021 May 28.

The Cambridge Centre for Sport & Exercise Sciences, Anglia Ruskin University, Cambridge CB1 1PT, UK.

Laparoscopy is a procedure that ultimately reduces hospital stay time and speeds up post-operative recovery. It is mainly performed in high-income countries but its implementation in many low- and middle-income countries (LMICs) is increasing. However, no aggregate data exist regarding the outcomes of this procedure in resource-limited settings. Read More

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Surgical Management of Gallstone Ileus in Low-Settings Hospital during COVID-19 Outbreak: A Case Report.

Surg J (N Y) 2021 Apr 25;7(2):e54-e58. Epub 2021 May 25.

University of Baghdad, Baghdad, Iraq.

 Gallstone ileus is a very infrequent complication of cholelithiasis in which single or multiple stones pass through an abnormal fistula to the lumen of the intestine leading to a true mechanical obstruction. We are reporting a case of a female who developed intestinal obstruction due to gallstones during the coronavirus disease 2019 (COVID-19) outbreak and was managed urgently surgically in a low-settings hospital.  An 85-year-old white female with 40 years history of gallstone disease, hypertension, and type-2 diabetes presented to the accidents and emergency unit with upper central crampy abdominal pain for 5 days associated with green color vomiting and absolute constipation. Read More

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Post-pregnancy recurrent biliary colic with intraoperative diagnosis of limy bile syndrome.

Int J Surg Case Rep 2021 May 13;83:105976. Epub 2021 May 13.

Department of Surgery, General and Oncologic Surgery Unit, Santa Croce e Carle Hospital, Cuneo, Italy.

Introduction: Limy bile syndrome (LBS) is an unusual condition in which gallbladder and/or bile ducts are filled with paste-like radiopaque material with a high calcium carbonate content. It can be rarely associated with PTH disorder and hypercalcemia.

Presentation Of Case: A 35-year-old woman presented with epigastric and right hypochondrium pain since a few hours. Read More

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Fetal intracranial hemorrhage associated with maternal coagulopathy and vitamin K deficiency after biliary drain placement: A case report and literature review.

Case Rep Womens Health 2021 Jul 20;31:e00329. Epub 2021 May 20.

Department of Obstetrics and Gynecology, Division of Maternal and Fetal Medicine, University of Arkansas for Medical Sciences, Little Rock, AR, United States of America.

Introduction: Fetal intracranial hemorrhage (ICH) is a rare but serious prenatal diagnosis. Predisposing factors include maternal trauma and fetal coagulation dysfunction. Maternal vitamin K deficiency has been described as an etiology. Read More

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How correct is the postponed cholecystectomy during the coronavirus disease-19 pandemic process? Gallstone ileus is not a myth anymore.

Cir Cir 2021 ;89(3):390-393

Department of General Surgery, University of Health Sciences, Haseki Training and Research Hospital, Istanbul, Turkey.

Posponer cirugías electivas durante el proceso pandémico de Covid-19 aumentó el riesgo de complicaciones graves de enfermedades benignas. El íleo biliar es una de las raras complicaciones de la colelitiasis (0,3-0,5%). Los episodios recurrentes de colecistitis aguda están involucrados en la fisiopatología. Read More

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Clinical and therapeutic features of acute cholecystitis in diabetic patients.

Exp Ther Med 2021 Jul 13;22(1):758. Epub 2021 May 13.

4th Surgery Department, Emergency University Hospital Bucharest, 050098 Bucharest, Romania.

The present study aimed to compare the clinical, paraclinical, intraoperative findings, and postoperative complications in acute cholecystitis in diabetic patients vs. non-diabetic patients. A 2-year retrospective study was performed on the patients who underwent emergency cholecystectomy for acute cholecystitis between 2017 and 2019 at the 4th Department of Surgery, Emergency University Hospital Bucharest. Read More

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Simple Blood Tests May Be Used to Predict the Increased Risk of Conversion in Elective Laparoscopic Cholecystectomy Surgery.

J Laparoendosc Adv Surg Tech A 2021 May 24. Epub 2021 May 24.

Department of General Surgery, SisliHamidiyeEtfal Medical Practice and Research Center, University of Health Sciences, Istanbul, Turkey.

In this study, we aimed to evaluate the possibility if simple blood tests that can be made in majority of hospitals may be used predict to risk of conversion to laparoscopic surgery to an open approach. The hospital records of 636 patients who underwent elective laparoscopic cholecystectomy (L-C) were retrospectively reviewed, and 583 patients included in the study protocol. Preoperative laboratory tests of all patients and data of patients who underwent conversion from laparoscopic surgery to open surgery were examined. Read More

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Large bowel obstruction secondary to gallstones.

J Surg Case Rep 2021 May 18;2021(5):rjab137. Epub 2021 May 18.

Department of Surgery, Lehigh Valley Health Network, Allentown, PA, USA.

Gallstone ileus is a rare complication of cholelithiasis, representing 1% of bowel obstructions. The usual site of obstruction is the ileocecal valve, though other sites have been reported. Here, we present two cases of gallstone ileus within the distal colon requiring surgical intervention. Read More

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Metastasis of missed cholangiocarcinoma in the left lobe through abdominal wall laparoscopic port-site and umbilicus after laparoscopic cholecystectomy: Case report and literature review.

Radiol Case Rep 2021 Jul 5;16(7):1785-1789. Epub 2021 May 5.

Departments of Radiology, Guangdong Hospital of Traditional Chinese Medicine, Zhuhai, 519000, China.

Laparoscopic cholecystectomy (LC) has been widely used by surgeons. However, the missed diagnosis of intraperitoneal malignant tumor may occur. If the malignancy exists, the changes of the abdominal environment or the laparoscopic operation might brought the cancer cells to abdominal cavity or wall, to more extreme condition, will be located in the navel, which is known as Sister Mary Joseph's nodule(SMJN). Read More

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Remaining issues of recommended management in current guidelines for asymptomatic common bile duct stones.

World J Gastroenterol 2021 May;27(18):2131-2140

Department of Gastroenterology, Kumamoto City Hospital, Kumamoto City 862-8505, Japan.

Current guidelines for treating asymptomatic common bile duct stones (CBDS) recommend stone removal, with endoscopic retrograde cholangiopancreatography (ERCP) being the first treatment choice. When deciding on ERCP treatment for asymptomatic CBDS, the risk of ERCP-related complications and outcome of natural history of asymptomatic CBDS should be compared. The incidence rate of ERCP-related complications, particularly of post-ERCP pancreatitis for asymptomatic CBDS, was reportedly higher than that of symptomatic CBDS, increasing the risk of ERCP-related complications for asymptomatic CBDS compared with that previously reported for biliopancreatic diseases. Read More

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[National survey on the treatment of cholelitiasis in Spain during the initial period of the COVID-19 pandemic].

Cir Esp 2021 May 19;99(5):346-353. Epub 2020 Jul 19.

Servicio de Cirugía, Hospital Universitario de Guadalajara, Guadalajara, España.

Introduction: The extraordinary impact of COVID-19 pandemic on Spanish hospitals has led to a redistribution of resources for the treatment of these patients, with a decreased capacity of care for other common diseases. The aim of the present study is to analyse how this situation has affected the treatment of cholecystitis and cholelythiasis.

Methods: It is a descriptive national study after online voluntary distribution of a specific questionnaire with Google Drive™ to members of the Spanish Association of Surgeons (AEC). Read More

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Usefulness of endoscopic ultrasound in patients with minilithiasis and/or biliary sludge as a cause of symptoms of probable biliary origin after cholecystectomy.

Gastroenterol Hepatol 2021 May 21. Epub 2021 May 21.

Department of Gastroenterology, Hospital Universitari Mútua Terrassa, Fundació per la Recerca Mútua Terrassa, Terrrassa, Catalonia, Spain; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBERehd), Spain. Electronic address:

Introduction: Endoscopic ultrasound (EUS) is a more sensitive technique than transabdominal ultrasound for the diagnosis of gallstones. This greater sensitivity, especially in the diagnosis of microlithiasis/biliary sludge, facilitates the indication of cholecystectomy in patients with symptoms of probable biliary origin but may result in over-indication of this surgery.

Objectives: Evaluate the role of EUS in the diagnosis of minilithiasis/biliary sludge in patients with digestive symptoms of probable biliary origin by resolving the symptoms after cholecystectomy. Read More

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Autoimmune polyendocrine syndrome type 1: an Italian survey on 158 patients.

J Endocrinol Invest 2021 May 18. Epub 2021 May 18.

FIRS Laboratories RSR Ltd, Cardiff, UK.

Background: Autoimmune Polyglandular Syndrome type 1 (APS-1) is a rare recessive inherited disease, caused by AutoImmune Regulator (AIRE) gene mutations and characterized by three major manifestations: chronic mucocutaneous candidiasis (CMC), chronic hypoparathyroidism (CH) and Addison's disease (AD).

Methods: Autoimmune conditions and associated autoantibodies (Abs) were analyzed in 158 Italian patients (103 females and 55 males; F/M 1.9/1) at the onset and during a follow-up of 23. Read More

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Analysis of SET and MYND Domain-Containing Protein 3 (SMYD3) Expression in Gallbladder Cancer: a Pilot Study.

Indian J Surg Oncol 2021 Apr 11;12(Suppl 1):111-117. Epub 2020 Jul 11.

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005 India.

The Suvar, Enhancer of zeste, and Trithorax (SET) and myeloid-Nervy-DEAF-1 (MYND) domain-containing protein 3 (SMYD3) is a histone lysine methyltransferase and has been recently unveiled to play significant roles in the progression of human cancer via regulating various key cancer-associated genes and pathways. The role of SMYD3 in gallbladder cancer (GBC) still needs to be studied. In the present study, we examined the SMYD3 gene expression at mRNA and protein level to look its impact on risk for developing gallbladder carcinogenesis. Read More

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Molecular Oncology of Gall Bladder Cancer.

Indian J Surg Oncol 2021 Apr 16;12(Suppl 1):57-64. Epub 2019 Nov 16.

Department of Surgical Oncology, King George's Medical University, Lucknow, Uttar Pradesh 226003 India.

Gall bladder carcinoma (GBC) is a worldwide problem, with a higher incidence in areas of the world where cholelithiasis is common. As GBC is usually diagnosed in an advanced stage, the mortality is high. An understanding of the molecular pathways of carcinogenesis and the mutations involved in the development and progression of GBC could be useful in early diagnosis. Read More

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Gemfibrozil-Induced Polyuria.

Eur J Case Rep Intern Med 2021 27;8(4):002546. Epub 2021 Apr 27.

Patient First Medical Center affiliated with Beaumont Hospital, Dearborn, Michigan USA.

Gemfibrozil is a lipid-regulating agent used mainly to treat patients with hypertriglyceridaemia, especially those at risk for acute pancreatitis. Like any other pharmacological agent, gemfibrozil has known adverse effects, mainly gastrointestinal, such as cholelithiasis, gallstones, elevated transaminase, and other non-specific symptoms including dyspepsia, nausea and vomiting. Other reported adverse reactions are dizziness and vertigo, myopathy and rhabdomyolysis, angioedema, urticaria and rash. Read More

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Clear-Cell Adenocarcinoma of the Gallbladder with Alpha-Fetoprotein Production: A Case Report and Review of the Literature.

Gastrointest Tumors 2021 Apr 27;8(2):52-57. Epub 2021 Jan 27.

Department of Urology, Indraprashtha Apollo Hospital, Delhi, India.

Gallbladder tumors are the fifth most common cancers of the gastrointestinal tract with poor prognosis and low survival. The most common type is adenocarcinoma of which the clear cell type is an unusual histologic variant with alpha-fetoprotein (AFP)-producing gallbladder carcinoma, reported extremely rarely, which makes the index case an uncommon entity. AFP secretion by gallbladder carcinomas may occur given the similar embryological origin of liver and gallbladder. Read More

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Laparoscopic Cholecystectomy for Gallbladder Dysfunction and Polyps: Incidence and Follow up.

JSLS 2021 Apr-Jun;25(2)

University Hospital Hairmyres, Lanarkshire, Scotland, UK.

Aim: This study aims to evaluate the incidence, indications, management, and long term follow up of cholecystectomy in patients with no gallstones, other than acalculous acute cholecystitis.

Methods: Prospectively collected data of 5675 patients undergoing laparoscopic cholecystectomy (LC) over 28 years was extracted and analyzed. Patients with biliary symptoms, no stones on ultrasound scans and abnormal hepatobiliary iminodiacetic acid scans, and those with confirmed gallbladder polyps (GBP) were included. Read More

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Upper Gastrointestinal Bleeding: A Potential Precursor to Bouveret's Syndrome.

Cureus 2021 Apr 8;13(4):e14368. Epub 2021 Apr 8.

Division of Gastroenterology and Hepatology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA.

Bouveret's syndrome is a rare complication of cholelithiasis. It is characterized by a gallstone entering the intestine through a cholecystoenteric fistula, impacting the duodenum and causing gastric outlet obstruction. Rarely, it presents with hematemesis and melena. Read More

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Acute Pancreatitis in Children: The Clinical Profile at a Tertiary Hospital.

Cureus 2021 May 6;13(5):e14871. Epub 2021 May 6.

Medicine, College of Medicine and Medical Sciences, Arabian Gulf University, Manama, BHR.

Objectives The clinical course and progression of acute pancreatitis are poorly understood to date, necessitating more studies of clinical profiles during the disease. Moreover, understanding the etiologies and clinical presentations of acute pancreatitis (AP) in children can contribute to early diagnosis and, hence, earlier interventions. Therefore, this article aims to study the clinical profiles of children with acute pancreatitis (AP) in relation to complications and other variables. Read More

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Horseshoe kidney leading to ERCP failure; innovative use of guide wire during laparoscopic CBD exploration: A case report.

Int J Surg Case Rep 2021 May 29;82:105927. Epub 2021 Apr 29.

Department of General Surgery, Mata Chanan Devi Hospital, New Delhi, India.

Introduction: Horseshoe kidneys are the most common fusion defect of the kidneys, which amounts to about 0.25% of the population. They are usually asymptomatic and are often identified incidentally. Read More

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A rare case of gallstone ileus-the unanswered question.

Chi Fai Tsang

J Surg Case Rep 2021 Apr 29;2021(4):rjab164. Epub 2021 Apr 29.

Department of General Surgery, Prince of Wales Hospital and Community Health Services, Sydney, New South Wales 2002, Australia.

Gallstone ileus is caused by an impaction of one or more gallstones within the gastrointestinal tract leading to mechanical intestinal obstruction. It is a rare complication of cholelithiasis and found in 2-3% of all cases associated with recurrent episodes of cholecystitis. This case study demonstrates an atypical presentation of gallstone ileus. Read More

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Elderly patients (≥ 80 years) with acute calculous cholangitis have similar outcomes as non-elderly patients (< 80 years): Propensity score-matched analysis.

World J Hepatol 2021 Apr;13(4):456-471

Department of General Surgery, Tan Tock Seng Hospital, Singapore 308433, Singapore.

Background: Acute cholangitis (AC) is a disease spectrum with varying extent of severity. Age ≥ 75 years forms part of the criteria for moderate (Grade II) severity in both the Tokyo Guidelines (TG13 and TG18). Aging is associated with reduced physiological reserves, frailty, and sarcopenia. Read More

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