37,852 results match your criteria Cholelithiasis


The Cholecystectomy As A Day Case (CAAD) Score: A Validated Score of Preoperative Predictors of Successful Day-Case Cholecystectomy Using the CholeS Data Set.

World J Surg 2019 Apr 23. Epub 2019 Apr 23.

Trent Oesophago-Gastric Unit, Nottingham University Hospitals NHS Trust, Nottingham City Hospital, Hucknall Road, Nottingham, NG5 1PB, UK.

Background: Day-case surgery is associated with significant patient and cost benefits. However, only 43% of cholecystectomy patients are discharged home the same day. One hypothesis is day-case cholecystectomy rates, defined as patients discharged the same day as their operation, may be improved by better assessment of patients using standard preoperative variables. Read More

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http://dx.doi.org/10.1007/s00268-019-04981-5DOI Listing

Lumen-apposing metal stent-assisted electrohydraulic lithotripsy and mechanical lithotripsy for cholelithiasis in a nonsurgical patient.

VideoGIE 2019 Apr 4;4(4):159-160. Epub 2019 Mar 4.

Division of Gastroenterology and Interventional Endoscopy, St. John Hospital and Medical Center, Detroit, Michigan, USA.

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https://linkinghub.elsevier.com/retrieve/pii/S24684481193000
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http://dx.doi.org/10.1016/j.vgie.2018.12.016DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6470361PMC
April 2019
1 Read

Safety and feasibility of cholecystectomy in octogenarians. Analysis of a single center series of 316 patients.

HPB (Oxford) 2019 Apr 20. Epub 2019 Apr 20.

General and Digestive Surgery Department, Hepato-Bilio-Pancreatic Surgery Department, Hospital Clínico San Carlos, Instituto de Investigación Sanitaria del Hospital Clínico San, Carlos (IdISSC), Madrid, Spain.

Introduction: Cholecystectomy is the treatment of choice for symptomatic cholelithiasis. However, outcomes for patients over 80years of age are not well studied. The primary aim of this study was to describe the safety and feasibility of cholecystectomy, including in the acute setting, in a cohort of patients≥80 years of age. Read More

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http://dx.doi.org/10.1016/j.hpb.2019.03.373DOI Listing

Novel Technique for Laparoscopic Common Bile Duct Exploration Using Endovascular Instrumentation.

Cureus 2019 Feb 9;11(2):e4041. Epub 2019 Feb 9.

Surgery, Midland Surgical Associates, Midland, USA.

Treatment of choledocholithiasis is sometimes a two-step process involving both surgeons and gastroenterologists. Common bile duct (CBD) exploration can be performed at the same time as cholecystectomy but often requires the use of rigid tools, increasing the risk of CBD damage. Here, we report the case of a 64-year-old man who presented with epigastric pain and a positive Murphy's sign. Read More

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http://dx.doi.org/10.7759/cureus.4041DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6456357PMC
February 2019

Histopathological Changes in Gallbladder Mucosa Associated with Cholelithiasis: A Prospective Study.

Niger J Surg 2019 Jan-Jun;25(1):21-25

Department of Surgery, GGS Medical College and Hospital, Faridkot, Punjab, India.

Background And Aims: Cholelithiasis is known to produce diverse histopathological changes in the gallbladder mucosa. In the present study, we aimed to find the correlation between various gallstone characteristics (i.e. Read More

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http://dx.doi.org/10.4103/njs.NJS_15_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6452760PMC

Incidence and Risk Factors for Cholelithiasis After Bariatric Surgery.

Obes Surg 2019 Apr 17. Epub 2019 Apr 17.

Bariatric and Metabolic Surgery Center, DIPRECA Hospital, Vital Apoquindo 1200, Las Condes, Santiago, Chile.

Background: Obesity and rapid weight loss after bariatric surgery (BS) are independent risk factors for development of cholelithiasis (CL), a prevalent disease in the Chilean population. This study aimed to determine the incidence of CL in obese Chilean patients 12 months after BS and identify risk factors for development of gallstones.

Methods: Retrospective study of patients who underwent BS in 2014. Read More

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http://link.springer.com/10.1007/s11695-019-03760-4
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http://dx.doi.org/10.1007/s11695-019-03760-4DOI Listing
April 2019
1 Read

Preoperative and postoperative risk factors in laparoscopic cholecystectomy converted to open surgery.

Adv Clin Exp Med 2019 Apr 13. Epub 2019 Apr 13.

General Surgery Department, Atatürk Research and Education Hospital, Ankara, Turkey.

Background: Laparoscopic cholecystectomy (LC) is nowadays the gold standard in the surgical treatment of cholelithiasis and gallbladder diseases. But sometimes it may be inevitable to convert it to open surgery to safely end the procedure.

Objectives: In this study, we aimed to investigate the risk factors for conversion to open surgery from LC. Read More

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http://dx.doi.org/10.17219/acem/81519DOI Listing
April 2019
1 Read

Efficiency of fluorescent cholangiography during laparoscopic cholecystectomy for subvesical bile ducts: A case report.

Int J Surg Case Rep 2019 Mar 30;57:194-196. Epub 2019 Mar 30.

Department of Gastroenterological Surgery, Ishikawa Prefectural Central Hospital, 2-1 Kuratsuki-Higashi, Kanazawa, 920-8530, Japan. Electronic address:

Introduction: The subvesical bile ducts are located in the peri-hepatic connective tissue of the gallbladder fossa. Injury of the subvesical bile ducts provokes the severe complication of bile leak. Until now, fluorescent cholangiography has been employed during hepatobiliary surgery. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612193016
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http://dx.doi.org/10.1016/j.ijscr.2019.03.042DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461590PMC
March 2019
1 Read

Simultaneous laparoscopic partial pericystectomy and cholecystectomy: Is it safe? A case report.

Int J Surg Case Rep 2019 Mar 28;57:190-193. Epub 2019 Mar 28.

Al-Mouwasat University Hospital, Damascus University, Faculty of Medicine, Damascus, Syria. Electronic address:

Background: Initial reservations regarding spillage and the ability to manage the cyst wall have been allayed by many reports which show satisfying results with minimal complications using laparoscopic techniques. Here, we study the possibility and safety of simultaneous laparoscopic pericystectomy with one of the most common laparoscopic procedure; laparoscopic cholecystectomy.

Case Presentation: A 37 y/o female from a rural area in Syria was referred to our clinic after one year of total pericystectomy from both right and left lobes of lung. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22102612193014
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http://dx.doi.org/10.1016/j.ijscr.2019.03.028DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6461566PMC
March 2019
3 Reads

Cytoplasmic Fibrillar Aggregates in Gallbladder Epithelium Are a Frequent Mimic of Cystoisospora in Pediatric Cholecystectomy Specimens.

Arch Pathol Lab Med 2019 Apr 10. Epub 2019 Apr 10.

From the Department of Pathology, University of Maryland Medical Center, Baltimore (Dr Rose); the Department of Pathology, The Ohio State University Wexner Medical Center, Columbus (Drs C. A. Arnold, Badizadegan, Carter, Conces, Kahwash, Nicol, and M. A. Arnold); and the Department of Pathology and Laboratory Medicine, Nationwide Children's Hospital, Columbus, Ohio (Drs Badizadegan, Carter, Conces, Kahwash, Nicol, and M. A. Arnold). Dr Carter is now with Indiana University Health, Southern Indiana Pathologists, Bloomington.

Context.—: Cystoisospora belli is an intracellular parasite associated with gastrointestinal disease in immunocompromised hosts. Although infection has been classically associated with intestinal disease, studies have identified Cystoisospora in the gallbladder of immunocompetent patients based on hematoxylin-eosin morphology. Read More

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http://dx.doi.org/10.5858/arpa.2018-0335-OADOI Listing
April 2019
1 Read

Structural characterization and screening of chemical markers of flavonoids in Lysimachiae Herba and Desmodii Styracifolii Herba by ultra high-performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry based metabolomics approach.

J Pharm Biomed Anal 2019 Apr 3;171:52-64. Epub 2019 Apr 3.

Department of Pharmaceutical Analysis, School of Pharmacy, Hebei Medical University, 361 East Zhongshan Road, Shijiazhuang, Hebei 050017, PR China. Electronic address:

In traditional Chinese medicine, Lysimachiae Herba (LH) and Desmodii Styracifolii Herba (DSH) have been widely used for the treatment of calculi, but there is a certain focus in clinical application. Flavonoids as their pharmacologically active substances were focusly studied to make clear of their chemical compositions and reveal the similarities and differences between LH and DHS by analysis of characteristic marker components at the molecular level. An ultra high performance liquid chromatography quadrupole time-of-flight tandem mass spectrometry (UPLC-QTOF-MS/MS) approach based on metabolite profiling was established. Read More

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http://dx.doi.org/10.1016/j.jpba.2019.04.003DOI Listing
April 2019
2 Reads

The Liver in Sickle Cell Disease.

Clin Liver Dis 2019 May 21;23(2):177-189. Epub 2019 Feb 21.

Institute of Liver Studies, King's College Hospital NHS Foundation Trust, Denmark Hill, London SE5 9RS, UK. Electronic address:

Patients with sickle cell disease can develop liver disease as a result of intrahepatic sickling of erythrocytes, viral hepatitis and iron overload secondary to multiple blood transfusions, and gallstone disease as a result of chronic hemolysis. The spectrum of clinical liver disease is wide and often multifactorial. Some patients develop cirrhosis that may progress to end-stage liver failure. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10893261183010
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http://dx.doi.org/10.1016/j.cld.2018.12.002DOI Listing
May 2019
3 Reads

Follicular cholecystitis: Clinicopathologic associations.

Hum Pathol 2019 Apr 1. Epub 2019 Apr 1.

Department of Pathology and Immunology, School of Medicine, Washington University in St. Louis, 425 S Euclid Ave, Campus Box 8118, St. Louis, MO, USA 63110.. Electronic address:

Follicular cholecystitis (FC) is a relatively rare entity with uncertain causal associations. In this study, we aimed to explore different clinicopathologic associations of FC, and to better characterize the entity. A retrospective review of archival H&E slides and pertinent clinical information was undertaken for all cholecystectomy cases with a rendered diagnosis of "follicular cholecystitis", from 1991 to 2017. Read More

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http://dx.doi.org/10.1016/j.humpath.2019.03.003DOI Listing
April 2019
3 Reads

Gallstone ileus of the sigmoid colon. A case repor.

Ann Ital Chir 2019 Mar 28;8. Epub 2019 Mar 28.

Gallstone ileus is a complication of cholelithiasis which is due to gallstone migration through a fistula between the gallbladder and the gastrointestinal tract followed by intraluminal impaction. This uncommon form of mechanical bowel obstruction occurs in <1% of patients with cholelithiasis. Gallstone ileus due to cholecystocolonic fistula is rare, and therefore appropriate surgical treatment is still a matter of debate. Read More

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March 2019
3 Reads

Effectiveness of Ursodeoxycholic Acid in the Prevention of Cholelithiasis After Sleeve Gastrectomy.

Obes Surg 2019 Apr 3. Epub 2019 Apr 3.

Service des Explorations Fonctionnelles, Centre Intégré Nord Francilien de prise en charge de l'Obésité (CINFO), Hôpital Louis Mourier (AP-HP), Université Paris Diderot, Sorbonne Paris Cité, 178 Rue des Renouillers, 92701, Colombes Cedex, France.

Purpose: The use of ursodeoxycholic acid (UDCA) to prevent gallstone formation after sleeve gastrectomy (SG) is still debated. Furthermore, no study has assessed the effectiveness of UDCA on gallstone formation after the first postoperative year. Our aim was to compare the incidence of cholelithiasis (CL) at 1 and 3 years after SG between patients treated or not treated with UDCA. Read More

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http://dx.doi.org/10.1007/s11695-019-03862-zDOI Listing
April 2019
1 Read

Hepatobiliary and pancreatic manifestations in inflammatory bowel diseases: a referral center study.

BMC Gastroenterol 2019 Apr 3;19(1):48. Epub 2019 Apr 3.

Department of Gastroenterology and Hepatology, Medical school and University of Ioannina, Ioannina, Greece.

Background: Hepatobiliary and pancreatic manifestations have been reported in patients with Crohn's disease or ulcerative colitis. Our aim was to describe the prevalence of hepatobiliary and pancreatic manifestations in inflammatory bowel disease and their association with the disease itself and the medications used.

Methods: Data were retrospectively extracted from the clinical records of patients followed up at our tertiary IBD referral Center. Read More

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http://dx.doi.org/10.1186/s12876-019-0967-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6446300PMC
April 2019
2 Reads

Sonography of Acute Cholecystitis and Its Mimics.

Radiol Clin North Am 2019 May 10;57(3):535-548. Epub 2019 Feb 10.

Department of Imaging Sciences, University of Rochester Medical Center, 601 Elmwood Avenue, Box 648, Rochester, NY 14642, USA.

Right upper quadrant (RUQ) abdominal pain is a common complaint. Acute cholecystitis (AC) is the primary diagnostic consideration in most adults presenting with acute onset RUQ abdominal pain; however, a variety of other conditions can mimic AC. Abdominal ultrasound (US) receives the highest score for imaging appropriateness for these patients. Read More

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http://dx.doi.org/10.1016/j.rcl.2019.01.002DOI Listing
May 2019
3 Reads

Interventional radiology-operated percutaneous cholecystoscopy with ultrasonic lithotripsy and stone basket retrieval: A treatment for symptomatic cholelithiasis in non-operative candidates.

J Med Imaging Radiat Oncol 2019 Mar 29. Epub 2019 Mar 29.

David Geffen School of Medicine at UCLA, Los Angeles, California, USA.

Interventional radiology-operated percutaneous endoscopy has seen a recent resurgence with potential to return to the scope of Interventional Radiology practice. Endoscopy adds a new dimension to the Interventional Radiology armamentarium by offering a unique opportunity to diagnose and treat conditions under direct visualization with improved maneuverability. Cholecystoscopy (gallbladder endoscopy), as a method for percutaneous removal of gallstones, is an effective treatment option in patients with symptomatic cholelithiasis who are poor candidates for surgical cholecystectomy. Read More

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https://onlinelibrary.wiley.com/doi/abs/10.1111/1754-9485.12
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http://dx.doi.org/10.1111/1754-9485.12879DOI Listing
March 2019
8 Reads

Low-Phospholipid Associated Cholelithiasis (LPAC) syndrome: A synthetic review.

J Visc Surg 2019 Mar 25. Epub 2019 Mar 25.

Service de chirurgie générale, digestive et transplantation hépatique et intestinale (general, digestive, liver transplant and intestinal surgery department), hôpital de la Croix Rousse, hospices civils de Lyon, 103, grande rue de la Croix-Rousse, 69317 Lyon cedex 04, France.

Low-Phospholipid Associated Cholelithiasis (LPAC) is a genetic disease responsible for the development of intrahepatic lithiasis. It is associated with a mutation of the ABCB4 gene which codes for protein MDR3, a biliary carrier. As a nosological entity, it is defined by presence of two of the three following criteria: age less than 40 years at onset of biliary symptoms, recurrence of biliary symptoms after cholecystectomy, and intrahepatic hyperechogenic foci detected by ultrasound. Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2019.02.006DOI Listing
March 2019
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Risk of cholangiocarcinoma in patients undergoing therapeutic endoscopic retrograde cholangiopancreatography or cholecystectomy: A population based study.

World J Gastrointest Oncol 2019 Mar;11(3):238-249

Institute of Medicine, Chung Shan Medical University, Taichung 40201, Taiwan.

Background: Cholangiocarcinoma is a highly lethal disease that had been underestimated in the past two decades. Many risk factors are well documented for in cholangiocarcinoma, but the impacts of advanced biliary interventions, like endoscopic sphincterotomy (ES), endoscopic papillary balloon dilatation (EPBD), and cholecystectomy, are inconsistent in the previous literature.

Aim: To clarify the risks of cholangiocarcinoma after ES/EPBD, cholecystectomy or no intervention for cholelithiasis using the National Health Insurance Research Database (NHIRD). Read More

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http://dx.doi.org/10.4251/wjgo.v11.i3.238DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6425330PMC
March 2019
1 Read

Surgical emergencies in pregnancy in the era of modern diagnostics and treatment.

Taiwan J Obstet Gynecol 2019 Mar;58(2):177-182

R.G.Kar Medical College and Hospital, India.

Pregnancy can be complicated with different surgical emergencies which may potentially endanger the mother as well as foetus. In the modern era of advanced diagnostics and treatments, neither of them in response to a surgical emergency in a pregnant woman should be delayed. Appropriate early intervention is essential to decrease the morbidity and mortality. Read More

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http://dx.doi.org/10.1016/j.tjog.2019.01.001DOI Listing
March 2019
1 Read

Cholelithiasis: Presentation and Management.

J Midwifery Womens Health 2019 Mar 25. Epub 2019 Mar 25.

University of Louisiana at Lafayette, Lafayette, LA.

Cholelithiasis affects approximately 15% of the US population. Rising trends in obesity and metabolic syndrome have contributed to an increase in diagnosis of cholelithiasis. There are several risk factors for cholelithiasis, both modifiable and nonmodifiable. Read More

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http://dx.doi.org/10.1111/jmwh.12959DOI Listing
March 2019
4 Reads

Role of 99mTc-HIDA Scan for Assessment of Gallbladder Dyskinesia and Comparison of Gallbladder Dyskinesia with Various Parameters in Laparoscopic Cholecystectomy Patients.

Minim Invasive Surg 2019 14;2019:5705039. Epub 2019 Feb 14.

General Surgery Department, Sri Ramachandra Medical University, Chennai, India.

Objectives: Pathogenesis of gallstone includes bile stasis due to defect in the gallbladder muscle contraction. Our aim of the study is to find out the role of 99mTc-HIDA scan in assessment of gallbladder dyskinesia in cholelithiasis patients before laparoscopic cholecystectomy and compare the gallbladder dyskinesia with various parameters like symptoms of patients, diabetic status of patients, gallstones size and number, and cholecystitis features in histopathology report after surgery.

Material And Method: This is a prospective observational study conducted at our hospital for three years. Read More

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http://dx.doi.org/10.1155/2019/5705039DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6393923PMC
February 2019
1 Read

Delayed laparoscopic cholecystectomy in a case of acute cholecystitis and intestinal malrotation type I.

Clin Pract 2019 Jan 20;9(1):1091. Epub 2019 Feb 20.

Internal Medicine Service, Alvarez Buylla Hospital, Mieres, Spain.

In adults, intestinal malrotation is an oligosymptomatic entity that is occasionally discovered during the course of diagnostic studies for other causes. In the case described herein, intestinal malrotation was discovered during investigation for cholelithiasis and acute cholecystitis. Malrotation may occur due to alterations in the asymmetric cellular dynamics of the mesentery responsible for intestinal shortening and unilateral retraction, this may occur as a secondary event following alterations in the expression of homeodomain transcription factors. Read More

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http://dx.doi.org/10.4081/cp.2019.1091DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6390095PMC
January 2019
5 Reads

Gallbladder Disease in Children: A 20-year Single-centre Experience.

Indian Pediatr 2019 Mar 19. Epub 2019 Mar 19.

Department of Pediatric Surgery, University Hospital of Split, Spinciceva; and University of Split, School of Medicine, Soltanska; Split, Croatia.

Objective: Aim of this study was to examine the changes in incidence of pediatric cholecystectomies.

Methods: Children were divided into two groups regarding year of surgery (Group I: 1998-2007; Group II: 2008-2017) and their characteristics were compared.

Results: Number of cholecystecomies increased from 11 to 34. Read More

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March 2019
1 Read

Abdominal pain and vomiting during pregnancy due to cholesterolosis.

BMJ Case Rep 2019 Mar 20;12(3). Epub 2019 Mar 20.

Department of Obstetrics and Gynecology, OLVG, Amsterdam, The Netherlands.

We present a 22-year-old pregnant woman at 15 weeks of gestation, with abdominal pain and vomiting. We demonstrate that diagnosis and treatment of vomiting and abdominal pain in pregnancy can be difficult. Therefore, involvement of other medical specialists is important when common treatments fail. Read More

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http://dx.doi.org/10.1136/bcr-2018-227826DOI Listing
March 2019
3 Reads

Massive hemoperitoneum and upper gastrointestinal hemorrhage following liver rupture secondary to gallbladder perforation: A case report and literature review.

Medicine (Baltimore) 2019 Mar;98(11):e14729

Department of Liver Surgery & Liver Transplantation Center, West China Hospital of Sichuan University, Chendu, Sichuan.

Rationale: Available literature states that the common reasons for non-traumatic spontaneous liver rupture are hepatocellular carcinoma, macronodular cirrhosis, hemangioma, and other tumors; gallbladder perforation is not cited as a cause.

Patient Concerns: The patient presented with sudden-onset right upper quadrant pain with tarry stool for 3 days after eating with dysphoria and increasing thirst; gradually, hemorrhagic shock developed. He had no history of trauma, no background of chronic hepatitis, and no cirrhosis. Read More

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http://dx.doi.org/10.1097/MD.0000000000014729DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6426586PMC
March 2019
1 Read

Prospective observational study on cholelithiasis in patients with carcinoma gall bladder in a tertiary referral hospital of Eastern India.

J Cancer Res Ther 2019 Jan-Mar;15(1):153-156

Department of Surgery, IPGMER/SSKM Hospital; Department of Surgical Oncology, Chittaranjan National Cancer Institute, Kolkata, West Bengal, India.

Context: Gallbladder carcinoma (GBCA) is the fifth most common types of gastrointestinal malignancy and is the most common malignancy of the biliary tract. Cholelithiasis, gallbladder polyps, porcelain gall, and choledochal cysts are common known associations with GBCA. Because of the better understanding of the etiopathogenesis, the traditional nihilistic attitude toward the prognosis has, over the years, given way to greater interest and hope for treating the disease. Read More

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http://dx.doi.org/10.4103/jcrt.JCRT_939_17DOI Listing
March 2019
2 Reads

[Gallbladder epidermoid carcinoma].

Rev Med Chil 2018 Dec;146(12):1438-1443

Departamento de Cirugía Oncológica Gastrointestinal, Instituto Nacional de Cancerología, México.

Background: Gallbladder epidermoid carcinoma is rare and more common in women over 55 years of age.

Aim: To report the features of 15 patients with gallbladder epidermoid carcinoma.

Material And Methods: Review of medical records of patients with gallbladder cancer in an oncology service. Read More

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http://dx.doi.org/10.4067/s0034-98872018001201438DOI Listing
December 2018
5 Reads

Technical Aspects of Bile Duct Evaluation and Exploration: An Update.

Surg Clin North Am 2019 Apr 10;99(2):259-282. Epub 2019 Feb 10.

Rutgers, New Jersey Medical School, 185 South Orange Avenue, MSB G586, Newark, NJ 07103, USA. Electronic address:

Consensus guidelines recommend patients with symptomatic cholelithiasis and suspected choledocholithiasis have common bile duct exploration (CBDE) at the time of cholecystectomy to prevent downstream problems. Despite superiority of single-stage cholecystectomy with CBDE, 2-stage precholecystectomy/postcholecystectomy with endoscopic clearance of the duct is commonly practiced. This is related to inadequate training in minimally invasive techniques, lack of technical support for efficient and safe CBDE, and surgeons' inexperience with complex biliary pathologic condition. Read More

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http://dx.doi.org/10.1016/j.suc.2018.12.007DOI Listing
April 2019
1 Read

An Update on Technical Aspects of Cholecystectomy.

Surg Clin North Am 2019 Apr 10;99(2):245-258. Epub 2019 Feb 10.

Division of Hepatobiliary, Pancreatic, and Gastrointestinal Surgery, Washington University School of Medicine, 660 South Euclid Avenue Box 8109, St Louis, MO 63110, USA. Electronic address:

Laparoscopic cholecystectomy has revolutionized the field of surgery, and is currently the gold standard in the treatment for symptomatic cholelithiasis. The goal of every laparoscopic cholecystectomy should be attainment of the critical view of safety before cutting the cystic duct and artery to reduce the risk of bile duct injury. Open cholecystectomy is most commonly performed when laparoscopic cholecystectomy is converted to open or when laparoscopic cholecystectomy is contraindicated. Read More

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http://dx.doi.org/10.1016/j.suc.2018.11.005DOI Listing

Gallstone Disease: Cholecystitis, Mirizzi Syndrome, Bouveret Syndrome, Gallstone Ileus.

Surg Clin North Am 2019 Apr;99(2):231-244

Rutgers, New Jersey Medical School, 185 South Orange Avenue, MSB G586, Newark, NJ 07102, USA.

Gallstone disease is a leading cause of morbidity in the United States and usually requires surgical or endoscopic interventions for diagnosis and/or treatment. Although gallstone disease is classically associated with the inflammatory sequela of cholecystitis, gallstones can also contribute to other clinical presentations such as gallstone ileus, Mirizzi syndrome, and Bouveret syndrome. This article explores the common-and uncommon-causes of surgical pathology owing to gallstones with an emphasis on clinical identification, diagnostics, and management options. Read More

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http://dx.doi.org/10.1016/j.suc.2018.12.006DOI Listing
April 2019
1 Read

Bile Metabolism and Lithogenesis: An Update.

Surg Clin North Am 2019 Apr;99(2):215-229

Department of Surgery, University of California Irvine; Hepatobiliary and Pancreas Surgery, Department of Surgery, University of California Irvine, Orange, CA, USA. Electronic address:

Bile is composed of multiple macromolecules, including bile acids, free cholesterol, phospholipids, bilirubin, and inorganic ions that aid in digestion, nutrient absorption, and disposal of the insoluble products of heme catabolism. The synthesis and release of bile acids is tightly controlled and dependent on feedback mechanisms that regulate enterohepatic circulation. Alterations in bile composition, impaired gallbladder relaxation, and accelerated nucleation are the principal mechanisms leading to biliary stone formation. Read More

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http://dx.doi.org/10.1016/j.suc.2018.12.003DOI Listing
April 2019
2 Reads

An Update on Biliary Dyskinesia.

Authors:
Clancy J Clark

Surg Clin North Am 2019 Apr;99(2):203-214

General Surgery Residency, Center for Applied and Experiential Learning, Wake Forest Baptist Health, Medical Center Boulevard, Winston Salem, NC 27157, USA. Electronic address:

Biliary dyskinesia is a functional disorder of the gallbladder or sphincter of Oddi. While cholecystectomy for symptomatic cholelithiasis is widely accepted, debate remains regarding the clinical benefit of invasive procedures for biliary dyskinesia. This article will review current best evidence in the diagnosis and management of biliary dyskinesia. Read More

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http://dx.doi.org/10.1016/j.suc.2018.11.004DOI Listing

Comparison of clinical characteristics and outcomes of pyogenic liver abscess patients < 65 years of age versus ≥ 65 years of age.

BMC Infect Dis 2019 Mar 7;19(1):233. Epub 2019 Mar 7.

National Local Joint Engineering Research Center for Precision Surgery & Regenerative Medicine, Shaanxi Provincial Center for Regenerative Medicine and Surgical Engineering, Institute of Advanced Surgical Technology and Engineering, First Affiliated Hospital, Xi'an Jiaotong University, 76 West Yanta Road, P.O. Box 124, Xi'an, 710061, Shaanxi Province, China.

Background: Pyogenic liver abscess (PLA) in the elderly is insufficiently elucidated. A few studies attempted to investigate the role of age in PLA have yielded controversial results. The purpose of this study was to explore the possible differences in the comorbidity, microbiological characteristics and clinical course between elderly and young PLA patients. Read More

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http://dx.doi.org/10.1186/s12879-019-3837-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407260PMC
March 2019
3 Reads

Sickle cell diseases: What can nuclear medicine offer?

Hell J Nucl Med 2019 Jan-Apr;22(1):2-3. Epub 2019 Mar 7.

Nuclear Medicine Unit, Interdisciplinary Department of Medicine, University of Bari "Aldo Moro", Bari, Italy.

Sickle cell disease (SCD) is the best known haemoglobinopathy, caused by a mutation substituting valina for glutamic acid at position 6 of the beta-globin chain of adult hemoglobin A, resulting in hemoglobin S (HbS). The homozygous HbS disease (HbSS), an autosomal recessive disorder, is the most common form and the Mediterranean area, along with sub-Saharian African and India, have the highest prevalence (1%-15%). In particular, Sicily with a prevalence of 2%-5%, is among the most interested regions. Read More

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http://dx.doi.org/10.1967/s002449910950DOI Listing
March 2019
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Safe laparoscopic cholecystectomy: Adoption of universal culture of safety in cholecystectomy.

World J Gastrointest Surg 2019 Feb;11(2):62-84

Transplant and HPB Surgery, the Iowa Clinic-Iowa Methodist Hospital, Des Moines, IA 50309, United States.

The incidence of biliary injury after laparoscopic cholecystectomy (LC) has shown a declining trend though it may still be twice that as with open cholecystectomy. Major biliary or vasculobiliary injury is associated with significant morbidity. As prevention is the best strategy, the concept of a culture of safe cholecystectomy has been recently introduced to educate surgeons and apprise them of basic tenets of safe performance of LC. Read More

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http://dx.doi.org/10.4240/wjgs.v11.i2.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397793PMC
February 2019
2 Reads

Predictors of abnormalities on magnetic resonance cholangiopancreatography: is there a role when the biliary tree is normal on previous imaging?

Ann Gastroenterol 2019 Mar-Apr;32(2):193-198. Epub 2019 Jan 15.

Department of Gastroenterology (Bhamini Vadhwana, John Graby, Martin Lewis, Anouchka Goldman, Kevin J. Monahan).

Background: There is limited evidence supporting the use of magnetic resonance cholangiopancreatography (MRCP) if the biliary tree is within normal limits on ultrasound scan (US) or computed tomography (CT). The aim of this study was to assess the role of MRCP in the absence of a dilated biliary system on index imaging.

Methods: A retrospective observational study of consecutive MRCP investigations (n=427) was performed between October 2010 and June 2013 at a single district general hospital. Read More

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http://dx.doi.org/10.20524/aog.2019.0352DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394272PMC
January 2019
1 Read

Frequency of Hepatobiliary Manifestations and Concomitant Liver Disease in Inflammatory Bowel Disease Patients.

Biomed Res Int 2019 31;2019:7604939. Epub 2019 Jan 31.

Department of Life Sciences, Universidade do Estado da Bahia, Rua Silveira Martins 2555, Cabula 41150-000, Salvador, Bahia, Brazil.

Background: In inflammatory bowel disease (IBD) patients there are reports of the occurrence of hepatobiliary manifestations, so the aim of this study was to evaluate the hepatobiliary manifestations in patients with Crohn's disease (CD) and ulcerative colitis (UC) from an IBD reference center.

Methods: Cross-sectional study in an IBD reference center, with interviews and review of medical charts, between July 2015 and August 2016. A questionnaire addressing epidemiological and clinical characteristics was used. Read More

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https://www.hindawi.com/journals/bmri/2019/7604939/
Publisher Site
http://dx.doi.org/10.1155/2019/7604939DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6374878PMC
January 2019
9 Reads

Big-data analysis: A clinical pathway on endoscopic retrograde cholangiopancreatography for common bile duct stones.

World J Gastroenterol 2019 Feb;25(8):1002-1011

Department of Gastroenterology, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing 210008, Jiangsu Province, China.

Background: A clinical pathway (CP) is a standardized approach for disease management. However, big data-based evidence is rarely involved in CP for related common bile duct (CBD) stones, let alone outcome comparisons before and after CP implementation.

Aim: To investigate the value of CP implementation in patients with CBD stones undergoing endoscopic retrograde cholangiopancreatography (ERCP). Read More

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https://www.wjgnet.com/1007-9327/full/v25/i8/1002.htm
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http://dx.doi.org/10.3748/wjg.v25.i8.1002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6397721PMC
February 2019
8 Reads
2.369 Impact Factor

Digital Affinity in Medical Students Influences Learning Outcome: A Cluster Analytical Design Comparing Vodcast With Traditional Lecture.

J Surg Educ 2019 May - Jun;76(3):711-719. Epub 2019 Mar 2.

Institute for Medical Teaching and Medical Educational Research, University Hospital Wuerzburg, Würzburg, Germany.

Background/objective: Undergraduate medical education still relies on lectures as the core teaching activity. However, e-learning and new media have begun to augment learning and information gathering over the last few years. The aim of this study was to investigate the effect of 2 teaching formats in surgical education, a classic lecture and a video podcast (vodcast), on knowledge gain, in particular with respect to the participants' characteristics and preferences. Read More

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http://dx.doi.org/10.1016/j.jsurg.2018.12.001DOI Listing
March 2019
4 Reads

Determinants for symptomatic gallstone disease readmissions - results from a cohort with screen-detected gallstone disease.

J Visc Surg 2019 Feb 26. Epub 2019 Feb 26.

Center for Clinical Research and Prevention, Bispebjerg and Frederiksberg Hospital, Nordre Fasanvej 57, 2000 Frederiksberg, Denmark; Department of Public Health, Faculty of Health and Medical Sciences, University of Copenhagen, Øster Farimagsgade 5, 1014 Copenhagen, Denmark; The Faculty of Medicine, Aalborg University, Niels Jernes Vej 10, 9220 Aalborg, Denmark.

Aim Of The Study: Selection of patients for cholecystectomy is hampered by lack of objective criteria. The objectives of this cohort study were to identify if patient, symptoms, or gallstone disease characteristics determined readmission in an unselected cohort with screen-detected gallstone disease and who had experienced a first admission with symptomatic gallstone disease.

Methods: Data from three random sampled population-based cohorts were used. Read More

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http://dx.doi.org/10.1016/j.jviscsurg.2019.02.005DOI Listing
February 2019
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Ectopic papilla of Vater in duodenum bulb: A hospital-based study.

Medicine (Baltimore) 2019 Feb;98(8):e14642

Division of Gastroenterology, Department of Internal Medicine, Taichung Tzu-Chi Hospital, Taichung, Taiwan.

The major papilla of Vater can be ectopically present in the stomach, pyloric canal, duodenal bulb, and third or fourth portion of the duodenum. In this study, we determined the clinical significance of ectopic papilla of Vater by endoscopic retrograde cholangiopancreatogram (ERCP).A retrospective study was conducted by reviewing the medical records of 6133 patients receiving ERCP from 1988 to 2011. Read More

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http://dx.doi.org/10.1097/MD.0000000000014642DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6407926PMC
February 2019
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Adolescent gallstones-need for early intervention in symptomatic idiopathic gallstones.

Pediatr Surg Int 2019 May 26;35(5):569-574. Epub 2019 Feb 26.

Department of Paediatric Surgery, John Hunter Children's Hospital, 2 Lookout Road, New Lambton Heights, Newcastle, NSW, 2305, Australia.

Background And Aim: Currently, there is a paucity of the literature describing the natural history of cholelithiasis (CL) and choledocholithiasis (CDL) in adolescent children. This study aims to analyse the changing demographics of paediatric and adolescent gallstones.

Methodology: Retrospective review of all children (Age 0-18 years) presenting with symptomatic gallstones over the last 15 years (2002-2017) at a single tertiary institution. Read More

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http://dx.doi.org/10.1007/s00383-019-04461-wDOI Listing
May 2019
2 Reads

Etiology and clinical characteristics of pediatric acute pancreatitis in Saudi Arabia: a 20-year experience from a single tertiary center.

Int J Pediatr Adolesc Med 2018 Mar 24;5(1):13-17. Epub 2018 Feb 24.

King Abdullah Specialist Children Hospital, Pediatric Gastroenterology, Riyadh, Saudi Arabia.

Background: Cases of acute pancreatitis (AP) have increased among pediatric populations worldwide; however, the natural course of this condition in Saudi Arabia was unknown.

Aim: To report the characteristics as well as outcomes of pediatric AP.

Patients And Methods: A retrospective chart review study was conducted to include acute pancreatitis in patients ≤ 19 years. Read More

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http://dx.doi.org/10.1016/j.ijpam.2018.01.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6363251PMC
March 2018
1 Read

"Endoscopic ultrasound first policy" in acute pancreatitis of presumed biliary origin.

Authors:
Vincent Zimmer

Am J Med 2019 Feb 22. Epub 2019 Feb 22.

Department of Medicine, Marienhausklinik St. Josef Kohlhof, Neunkirchen, Germany; Department of Medicine II, Saarland University Medical Center, Saarland University Homburg, Germany. Electronic address:

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http://dx.doi.org/10.1016/j.amjmed.2019.01.033DOI Listing
February 2019
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Conservative Management of Gallstone Disease in the Elderly Population: Outcomes and Recurrence.

Scand J Surg 2019 Feb 21:1457496919832147. Epub 2019 Feb 21.

1 Department of General and Digestive Surgery, Hospital Universitario de la Princesa, Madrid, Spain.

Background & Aims:: The prevalence of gallstone disease increases with age, being early cholecystectomy the most accepted treatment in the vast majority of patients in order to prevent complications and recurrence. The aim of this study is to determine the recurrence rate and its possible predictors after initial non-operative management.

Materials And Methods:: We reviewed a consecutive series of patients, older than 65 years, admitted for a gallstone-related disease and treated with a non-operative management between January 2010 and December 2013. Read More

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http://dx.doi.org/10.1177/1457496919832147DOI Listing
February 2019
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Cholesterol cholelithiasis: part of a systemic metabolic disease, prone to primary prevention.

Expert Rev Gastroenterol Hepatol 2019 Feb 27;13(2):157-171. Epub 2018 Nov 27.

c Department of Biomedical Sciences and Human Oncology, Clinica Medica "A. Murri" , University of Bari Medical School , Bari , Italy.

Introduction: Cholesterol gallstone disease have relationships with various conditions linked with insulin resistance, but also with heart disease, atherosclerosis, and cancer. These associations derive from mechanisms active at a local (i.e. Read More

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http://dx.doi.org/10.1080/17474124.2019.1549988DOI Listing
February 2019
4 Reads