38,576 results match your criteria Cholelithiasis


Successful endoscopic treatment of a large impacted gallstone in the duodenum using laser lithotripsy, Bouveret's syndrome: A case report.

World J Gastroenterol 2020 May;26(19):2458-2463

Department of Gastroenterology, Franciscus Gasthuis & Vlietland, Rotterdam 3045 PM, Zuid-Holland, Netherlands.

Background: Bouveret´s syndrome is defined as a gastric outlet obstruction after passage of a gallstone through a fistula into the duodenum. Due to its rarity, the diagnosis of Bouveret's syndrome is often delayed and causes a high morbidity and mortality rate.

Case Summary: A 93-year-old female presented with worsening pain in the right upper abdomen and vomiting. Read More

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http://dx.doi.org/10.3748/wjg.v26.i19.2458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7243648PMC

Laparoscopic cholecystectomy in a patient with situs inversus totalis after videolaparoscopic sleeve-Case report.

Int J Surg Case Rep 2020 May 19;71:202-204. Epub 2020 May 19.

Clementino Fraga Filho University Hospital (HUCFF - UFRJ), Brazil.

Introduction: Situs inversus totalis is the technical term used when there is a complete transposition of all organs to the opposite side referring to classical embryogenic orientation. Laparoscopic cholecystectomy is one of the most performed surgeries in the world.

Presentation Of Case: We report the case of a 61-year-old female patient who had previously undergone videolaparoscopic gastroplasty 7 months ago, who developed refractary biliary colic and underwent videolaparoscopic cholecystectomy. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.045DOI Listing

Evidence-Based Management of Calculous Biliary Disease for the Acute Care Surgeon.

Surg Infect (Larchmt) 2020 May 29. Epub 2020 May 29.

Department of Surgery, University of Michigan, Ann Arbor, Michigan, USA.

Gallstones and cholecystitis are common clinical problems. There is a wide spectrum of disease severity, from rare symptoms of biliary colic to severe cholecystitis with marked gallbladder infection and inflammation that can cause life-threatening sepsis. The care of such patients is similarly varied and multi-disciplinary. Read More

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http://dx.doi.org/10.1089/sur.2020.110DOI Listing

Perioperative outcomes of the patients treated using laparoscopic cholecystectomy after emergent endoscopic retrograde cholangiopancreatography for bile duct stones: Does timing matter?

Ulus Travma Acil Cerrahi Derg 2020 May;26(3):396-404

Department of General Surgery, University of Health Sciences Gülhane Training and Research Hospital, Ankara-Turkey.

Background: There is no consensus on the optimal timing for laparoscopic cholecystectomy (LC) after emergent endoscopic retrograde cholangiopancreatography (ERCP) for suspected choledocholithiasis. Although certain data suggest that an early interval or single-stage treatment by LC, together with laparoscopic bile duct exploration, has more favorable outcomes, delayed LC is most often preferred as the standard treatment of patients with gallstones and choledocholithiasis following ERCP due to lack of experience, necessary instrumentation, or organizational restrictions. This study aims to compare the effects of different time intervals between ERCP and LC on perioperative outcomes. Read More

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http://dx.doi.org/10.14744/tjtes.2020.94401DOI Listing

Review on gall bladder myeloid sarcoma: a great masquerader.

Chin Clin Oncol 2020 May 20. Epub 2020 May 20.

Hemato-Oncology Division, Department of Internal Medicine, Saint Vincent Hospital, Worcester, MA, USA.

Pain in abdomen has wide differentials and narrowing down the clinical possibilities depends on type of pain, location, characterization which is usually assisted by imaging studies. Cholecystitis and cholelithiasis are amongst the common causes of acute abdomen. This study reviews the literature for the clinical characteristics, differential diagnosis, treatment and prognosis of reported cases of gallbladder myeloid sarcoma (GB-MS) who presented with abdominal symptoms. Read More

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http://dx.doi.org/10.21037/cco-19-250DOI Listing

Giant stentolith: A rare complication of long-dwelling biliary endoprosthesis.

Arab J Gastroenterol 2020 May 15. Epub 2020 May 15.

Department of Surgical Gastroenterology, King George's Medical University, Lucknow, UP, India.

Endoscopic biliary stenting is performed for various indications in routine clinical practice. Plastic stents are indicated primarily for short-term biliary decompression and require removal or exchange after 12-16 weeks. However, patients who become asymptomatic after the procedure may not return for scheduled stent removal and subsequently present with severe complications. Read More

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http://dx.doi.org/10.1016/j.ajg.2020.04.008DOI Listing

Simultaneous surgical treatment tactics of acute destructive cholecystitis combined with choledocholithiasis: A case report.

Int J Surg Case Rep 2020 May 12;70:230-233. Epub 2020 May 12.

Department of Surgery, Asfendiyarov Kazakh National Medical University, 050012 Almaty, Kazakhstan; City Clinical Hospital No. 4, 050054 Almaty, Kazakhstan.

Introduction: The widespread development of minimally invasive treatment methods have expanded the choices and options available to surgeons to manage patients suffering from cholelithiasis and its complications, including choledocholithiasis. As new surgical strategies are developed and become widely available, there is an ongoing debate as to which surgical strategies are optimal for the management of acute cholecystitis and concomitant choledocholithiasis. The treatment of patients in this category should be carried out according to clear criteria, taking into consideration the patient's condition, concomitant diseases, the size of calculi in the common bile duct as well as the resources of the medical institution. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.081DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7231816PMC

Incidence of and risk factors for late cholecystectomy in survivors of childhood cancer: A report from the Childhood Cancer Survivor Study.

Eur J Cancer 2020 May 15;133:4-13. Epub 2020 May 15.

Department of Surgery, Boston Children's Hospital and Harvard Medical School, Boston, MA, USA; Department of Paediatric Oncology, Dana-Farber Cancer Institute and Harvard Medical School, Boston, MA, USA.

Background: Gallbladder disease and need for cholecystectomy are common and significant contributors to patient morbidity and healthcare costs. Childhood cancer survivors are at elevated risk for developing cholelithiasis. However, their incidence of and risk factors for late (>5 years from diagnosis) cholecystectomy have not been studied. Read More

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http://dx.doi.org/10.1016/j.ejca.2020.03.004DOI Listing

Is concomitant cholecystectomy safe during abdominal wall reconstruction? An AHSQC analysis.

Hernia 2020 May 16. Epub 2020 May 16.

Comprehensive Hernia Center, Digestive Disease and Surgery Institute, Cleveland Clinic Foundation, Cleveland, OH, 44195, USA.

Purpose: Unlike routine ventral hernia repair, abdominal wall reconstruction (AWR) can results in large pieces of mesh and extensive manipulation of the intra-abdominal contents, rendering subsequent laparoscopic cholecystectomy challenging. This study addresses the additional wound morbidity of concomitant cholecystectomy.

Methods: The Americas Hernia Society Quality Collaborative (AHSQC) was retrospectively reviewed and logistic regression modeling was used to control for multiple covariates. Read More

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http://dx.doi.org/10.1007/s10029-020-02208-4DOI Listing

Same-day endoscopic ultrasound, retrograde cholangiopancreatography and stone extraction, followed by cholecystectomy: A case report and literature review.

Int J Surg Case Rep 2020 May 11;70:115-118. Epub 2020 May 11.

Departments of Surgery and Gastroenterology, Charles-LeMoyne Hospital, Greenfield Park, Canada.

Introduction: Common bile duct stone-related events and their recurrence are frequent even after endoscopic retrograde cholangiopancreatography and stone extraction. Cholecystectomy should be carried out as soon as possible after the initial episode to prevent complications.

Case Presentation: We present a case of a patient who underwent endoscopic ultrasound, cholangiopancreatography with stone extraction and cholecystectomy on the same day. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.04.063DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7229231PMC

The increasing prevalence and adverse impact of morbid obesity in paediatric acute pancreatitis.

Pediatr Obes 2020 May 14:e12643. Epub 2020 May 14.

Division of Gastroenterology, Hepatology, and Nutrition, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.

Objective: Morbid obesity is proinflammatory has been associated with adverse clinical outcomes in acute pancreatitis (AP) among adults. Obesity is increasingly prevalent in children and hence, we sought to evaluate the impact of morbid obesity on the clinical outcomes of AP using a large paediatric population-based cohort.

Methods: We analysed the US Kids' Inpatient Database between years 2003 and 2016 to include all patients (age ≤ 21 years) with a primary diagnosis of AP using specific ICD-9-CM and ICD-10-CM codes. Read More

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http://dx.doi.org/10.1111/ijpo.12643DOI Listing

Plasma Procalcitonin Is Useful for Predicting the Severity of Acute Cholecystitis.

Emerg Med Int 2020 14;2020:8329310. Epub 2020 Jan 14.

Eskisehir Osmangazi University Medical Center, Department of Emergency Medicine, Meselik, 26480 Eskisehir, Turkey.

Background: Acute cholecystitis is a common complication of cholelithiasis. Delayed diagnosis may constitute morbidity and mortality; therefore, early diagnosis and determining the severity of acute cholecystitis are crucial.

Objectives: This study aimed to determine the validity of blood procalcitonin (PCT) levels in assessing the severity of acute cholecystitis. Read More

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http://dx.doi.org/10.1155/2020/8329310DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7201449PMC
January 2020

"Analysis of readmissions to the emergency department among patients presenting with abdominal pain".

BMC Emerg Med 2020 May 12;20(1):37. Epub 2020 May 12.

2nd Department of General Surgery, Jagiellonian University Medical College, Kopernika 21 St, 31-501, Cracow, Poland.

Background: Abdominal pain is one of the most common complaints among patients admitted to the Emergency Department (ED). Diagnosis and management of abdominal pain may be a challenge and there are patients who require admission to the ED more than once in a short period of time. Our purpose was to assess the incidence of readmissions among patients treated in the ED due to abdominal pain and to investigate the impact of readmission on the further course of treatment. Read More

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http://dx.doi.org/10.1186/s12873-020-00334-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7216723PMC

A Single-Center Experience with Minimally Invasive Transgastric ERCP in Patients with Previous Gastric Bypass: Lessons Learned and Technical Considerations.

Am Surg 2020 Apr;86(4):300-307

As bariatric surgery increases, there is a growing population of patients with biliary obstruction and anatomy which precludes transoral access through endoscopic retrograde cholangiopancreatography (ERCP). Minimally invasive transgastric ERCP (TG-ERCP) offers a feasible alternative for the treatment. A retrospective review was performed of all patients who underwent laparoscopic or robotic-assisted TG-ERCP between 2010 and 2017. Read More

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Choledochal cyst- unusual presentation in the adult phase: Case report.

Int J Surg Case Rep 2020 Apr 2;70:33-36. Epub 2020 Apr 2.

Digestive System Surgery Service at Getúlio Vargas Teaching Hospital (HUGV), Avenida Apurinã, 4 - Praça 14 de Janeiro, Manaus, Amazonas, 69020-170, Brazil. Electronic address:

Introduction: Bile duct cysts are congenital malformations characterized by bile duct dilatation with intra and/or extrahepatic localization. About 80% of cases are diagnosed in childhood, so their presentation in adults is rare and repeatedly associated with complications.

Presentation Of Case: A 38-year-old female patient complained of severe abdominal pain for one month, with no associated cholestatic signs. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.03.014DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210471PMC

[Descending Colon Cancer with Synchronous Solitary Small Intestinal Metastasis-A Case Report].

Gan To Kagaku Ryoho 2020 Jan;47(1):120-122

Dept. of Surgical Oncology, Osaka City Juso Hospital.

A 77-year-old man presented with biliary colic and was diagnosed with descending colon cancer and cholelithiasis.During the surgery, a mass was detected in the upper jejunum, located 5 cm from the Treitz ligament on the anal side.Open left hemicolectomy with partial jejunal resection was performed. Read More

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January 2020

Variants in ABCB4 (MDR3) across the spectrum of cholestatic liver diseases in adults.

J Hepatol 2020 May 3. Epub 2020 May 3.

Division of Gastroenterology and Hepatology, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria. Electronic address:

The ATP binding cassette subfamily B member 4 (ABCB4) gene on chromosome 7 encodes the ABCB4 protein (alias multi drug resistance 3 protein [MDR3]), a P-glycoprotein in the canalicular membrane of the hepatocytes that acts as a translocator of phospholipids into bile. Several variants in ABCB4 have been identified so far that lead to ABCB4 deficiency accounting for a disease spectrum ranging from progressive familial cholestasis type 3 (PFIC-3) to less severe forms presenting as low phospholipid associated cholelithiasis (LPAC), intrahepatic cholestasis of pregnancy (ICP) or drug-induced liver injury (DILI). Furthermore, whole genome sequencing identified ABCB4 variants to be associated with an increased incidence of gallstone disease, gallbladder and cholangiocarcinoma, liver cirrhosis or elevated liver function tests. Read More

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http://dx.doi.org/10.1016/j.jhep.2020.04.036DOI Listing

A unusual case of multifocal pyogenic abscess formation following ERCP procedure.

BMC Surg 2020 May 6;20(1):92. Epub 2020 May 6.

Department of Surgery A, Galilee Medical Center, Nahariya, Israel.

Background: Endoscopic retrograde cholangiopancreatography (ERCP) is essential for managing biliary and pancreatic disorders. Infection is the most morbid complication of ERCP and among the most common causes of ERCP-related death.

Case Presentation: A 69-year-old man presented with right upper quadrant abdominal pain, obstructive jaundice and abnormal liver function tests. Read More

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http://dx.doi.org/10.1186/s12893-020-00759-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7203808PMC

Laparoscopic Cholecystectomy in the Cirrhotic: Review of Literature on Indications and Technique.

Chirurgia (Bucur) 2020 Mar-Apr;115(2):208-212

Cholelithiasis is twice more common in patients suffering from liver cirrhosis compared to overall population and in those patients, acute cholecystitis occurs significantly more often. Our goal was to review the literature and to overview the indications, contra-indications, and alternatives in the cirrhotic with biliary stones. We conducted a systematic review of the literature using the key words "Cirrhosis", "cholecystectomy", "laparoscopy"and "indications". Read More

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http://dx.doi.org/10.21614/chirurgia.115.2.208DOI Listing

Genetic mutational analysis of β-catenin gene affecting GSK-3β phosphorylation plays a role in gallbladder carcinogenesis: Results from a case control study.

Cancer Treat Res Commun 2020 Apr 21;23:100173. Epub 2020 Apr 21.

Department of General Surgery, Institute of Medical Sciences, Banaras Hindu University, Varanasi, 221 005, India. Electronic address:

This manuscript has reported different mutations of β-catenin gene in gallbladder cancer patients which affect GSK-3β phosphorylation site.

Purpose: Gallbladder carcinoma (GBC) is a relatively rare and fatal cancer with poor prognosis. The molecular mechanism of gallbladder carcinogenesis is still not clear. Read More

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http://dx.doi.org/10.1016/j.ctarc.2020.100173DOI Listing

Evaluation of Liver Function Tests and Serum Bilirubin Levels After Laparoscopic Cholecystectomy.

Med Arch 2020 Feb;74(1):24-27

Department of General Surgery, Faculty of Medicine, Poursina Hospital, Guilan University of Medical Sciences, Rasht, IR Iran.

Introduction: Laparoscopic cholecystectomy has been known as one of the most important prevalent and minimally invasive surgeries in medicine.

Aim: The aim here was to investigate the changes in liver enzymes and bilirubin levels after laparoscopic cholecystectomy in patients diagnosed with chronic cholecystitis.

Methods: This cross-sectional study was conducted at Poursina Hospital (Rasht, Iran) and 128 patients who met both inclusion and exclusion criteria were enrolled for further investigations. Read More

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http://dx.doi.org/10.5455/medarh.2020.74.24-27DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7164731PMC
February 2020

Bouveret syndrome as a rare cause of gastric outlet obstruction.

Proc (Bayl Univ Med Cent) 2020 Apr 10;33(2):235-236. Epub 2020 Jan 10.

Department of Gastroenterology, Upstate Medical UniversitySyracuseNew York.

Biliary-enteric fistula is a rare complication of cholelithiasis that can lead to gallstone ileus. Gallstone impaction in the duodenum and pylorus is extremely rare and can lead to gastric outlet obstruction, a condition known as Bouveret syndrome. Bouveret syndrome needs to be diagnosed and managed in a timely fashion, as it has a high mortality rate. Read More

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http://dx.doi.org/10.1080/08998280.2019.1708841DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7155981PMC

Development of an artificial intelligence system using deep learning to indicate anatomical landmarks during laparoscopic cholecystectomy.

Surg Endosc 2020 Apr 18. Epub 2020 Apr 18.

Faculty of Medicine, Department of Gastroenterological and Pediatric Surgery, Oita University, 1-1 Idaigaoka, Hasama-machi, Yufu-City, Oita, 879-5593, Japan.

Background: The occurrence of bile duct injury (BDI) during laparoscopic cholecystectomy (LC) is an important medical issue. Expert surgeons prevent intraoperative BDI by identifying four landmarks. The present study aimed to develop a system that outlines these landmarks on endoscopic images in real time. Read More

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http://dx.doi.org/10.1007/s00464-020-07548-xDOI Listing

Depletion of hepatic forkhead box O1 does not affect cholelithiasis in male and female mice.

J Biol Chem 2020 May 9;295(20):7003-7017. Epub 2020 Apr 9.

Division of Endocrinology and Diabetes, Department of Pediatrics, UPMC Children's Hospital of Pittsburgh, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania 15224

Cholelithiasis is one of the most prevalent gastroenterological diseases and is characterized by the formation of gallstones in the gallbladder. Both clinical and preclinical data indicate that obesity, along with comorbidity insulin resistance, is a predisposing factor for cholelithiasis. Forkhead box O1 (FoxO1) is a key transcription factor that integrates insulin signaling with hepatic metabolism and becomes deregulated in the insulin-resistant liver, contributing to dyslipidemia in obesity. Read More

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http://dx.doi.org/10.1074/jbc.RA119.012272DOI Listing

[Optimal dates of surgery for acute calculous cholecystitis].

Khirurgiia (Mosk) 2020 (3):56-60

A.I. Evdokimov Moscow State University of Medicine and Dentistry of the Ministry of Health of Russia, Moscow, Russia.

Objective: To analyze the results of surgical treatment of acute calculous cholecystitis depending on dates of surgery.

Material And Methods: There were 123 patients with acute calculous cholecystitis in 2017. The sample enrolled 111 females (90. Read More

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http://dx.doi.org/10.17116/hirurgia202003156DOI Listing

Association of Body Mass Index and Diet with Symptomatic Gall Stone Disease: A Case-Control Study.

Cureus 2020 Mar 5;12(3):e7188. Epub 2020 Mar 5.

Surgery, Texas Tech University Health Sciences Center, Lubbock, USA.

Background: Gall stone disease (GSD) is one of the commonest gastrointestinal disorders. Causative factors can be non-modifiable as genetics and modifiable like dietary habits. High-fat diet and high BMI are well known contributing factors world-over. Read More

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http://dx.doi.org/10.7759/cureus.7188DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7135725PMC

Two cases of agenesis of the dorsal pancreas and a review of the literature.

BMC Gastroenterol 2020 Apr 6;20(1):94. Epub 2020 Apr 6.

Department of General Surgery, Xuanwu Hospital, Capital Medical University, No.45 Changchun Street, Beijing, 100053, China.

Background: Agenesis of the dorsal pancreas (ADP) is a very rare disease with no specific symptoms, and the pathogenesis is not clear. Some patients will be accompanied by other diseases, such as pancreatic tumor or pancreatitis. But most cases are very atypical and difficult to distinguish. Read More

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http://dx.doi.org/10.1186/s12876-020-01245-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7137410PMC

Laparoscopic-guided versus transincisional rectus sheath block for pediatric single-incision laparoscopic cholecystectomy: A randomized controlled trial.

J Pediatr Surg 2020 Mar 12. Epub 2020 Mar 12.

Division of Pediatric Surgery, Johns Hopkins All Children's Hospital, St. Petersburg, Florida, USA. Electronic address:

Purpose: The purpose of our study was to compare the effectiveness of transincisional (TI) versus laparoscopic-guided (LG) rectus sheath block (RSB) for pain control following pediatric single-incision laparoscopic cholecystectomy (SILC).

Methods: Forty-eight patients 10-21 years old presenting to a single institution for SILC from 2015 to 2018 were randomized to TI or LG RSB. Apart from RSB technique, perioperative care protocols were identical between groups. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2020.03.002DOI Listing

The Treatment of Gallstone Disease.

Dtsch Arztebl Int 2020 Feb;117(9):148-158

Department of General, Abdominal, Thoracic, and Vascular Surgery, Memmingen Hospital, Memmingen Department of Internal Medicine II (Gastroenterology, Hepatology, Endocrinology, Diabetology, and Nutritional Medicine), Saarland University Hospital, Homburg.

Background: Gallstone disease affects up to 20% of the European population, and cholelithiasis is the most common reason for hospitalization in gastroenterology.

Methods: This review is based on pertinent publications retrieved by a selective search of the literature, including the German clinical practice guidelines on the diagnosis and treatment of gallstones and corresponding guidelines from abroad.

Results: Regular physical activity and an appropriate diet are the most important measures for the prevention of gallstone disease. Read More

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http://dx.doi.org/10.3238/arztebl.2020.0148DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7132079PMC
February 2020

A novel etiologic factor of highly elevated cholestanol levels: progressive familial intrahepatic cholestasis.

J Pediatr Endocrinol Metab 2020 May;33(5):665-669

Pediatric Metabolism, Ministry of Health Ankara City Hospital, University of Health Science, Ankara, Turkey.

Background Progressive familial intrahepatic cholestasis type 3 (PFIC3) is an uncommon cholestatic liver disease caused by mutations in the ATP binding cassette subfamily B member 4 (ABCB4) gene. Although PFIC3 is frequently identified in childhood, ABCB4 disease-causing alleles have been described in adults affected by intrahepatic cholestasis of pregnancy, hormone-induced cholestasis, low-phospholipid-associated cholelithiasis syndrome or juvenile cholelithiasis, cholangiocarcinoma and in sporadic forms of primary biliary cirrhosis. Cholestanol is a biomarker which is elevated especially in cerebrotendinous xanthomatosis and rarely in primary biliary cirrhosis (PBC) and Niemann Pick type C. Read More

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http://dx.doi.org/10.1515/jpem-2019-0314DOI Listing

Cholelithiasis After Sleeve Gastrectomy and Effectiveness of Ursodeoxycholic Acid Treatment.

J Laparoendosc Adv Surg Tech A 2020 Mar 31. Epub 2020 Mar 31.

İstanbul Bariatrics, Obesity and Advanced Laparoscopy Center, İstanbul, Turkey.

Few adverse effects may occur after bariatric surgery, one being the formation of gallstones. The aim of this study is to determine the incidence of cholelithiasis after laparoscopic sleeve gastrectomy (LSG) and whether ursodeoxycholic acid (UDCA) treatment reduces gallstone formation. Gall bladders of all patients planned for LSG were preoperatively checked by ultrasonography (USG). Read More

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http://dx.doi.org/10.1089/lap.2020.0077DOI Listing

Relationship of Cholelithiasis and Urolithiasis with Methylenetetrahydrofolate Reductase Polymorphisms.

J Invest Surg 2020 Mar 31:1-4. Epub 2020 Mar 31.

Division of Perinatology, Hacettepe University, Ankara, Turkey.

To investigate the relationship of cholelithiasis and urolithiasis with (MTHFR) polymorphism(s) in patients with poor obstetric history to search whether they are risk factors for adverse pregnancy outcome. This study is consisted of 94 patients with poor obstetric history. Patients were evaluated in terms of the presence of cholelithiasis and urolithiasis in association with MTHFR polymorphism(s). Read More

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http://dx.doi.org/10.1080/08941939.2020.1742402DOI Listing

Radiation exposure during endoscopic retrograde cholangiopancreatography according to clinical determinants.

Medicine (Baltimore) 2020 Mar;99(13):e19498

Division of Gastroenterology and Hepatology, Department of Internal Medicine, Korea University College of Medicine, Seoul, Republic of Korea.

This study aimed to analyze the dose of radiation to which the physician is exposed during endoscopic retrograde cholangiopancreatography (ERCP) and to identify predictive factors of radiation exposure during the procedure. Furthermore, we evaluated the patient characteristics and procedural factors associated with prolonged fluoroscopy time (FT).A cross-sectional retrospective analysis of 780 ERCPs performed at a tertiary academic hospital over a 2-year period was conducted. Read More

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http://dx.doi.org/10.1097/MD.0000000000019498DOI Listing

Acute Abdominal Pain: Missed Diagnoses, Extra-Abdominal Conditions, and Outcomes.

J Clin Med 2020 Mar 25;9(4). Epub 2020 Mar 25.

Department of Emergency Medicine, University Hospital Basel, 4051 Basel, Switzerland.

Abdominal pain (AP) is a common reason for presentation to an emergency department (ED). With this prospective, observational all-comer study, we aimed to answer three questions: Which diagnoses are most often missed? What is the incidence of extra-abdominal causes? What is the prognosis of abdominal pain in a tertiary urban European ED? Participants were systematically interviewed for the presence of 35 predefined symptoms. For all patients with abdominal pain, the index visit diagnoses were recorded. Read More

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http://dx.doi.org/10.3390/jcm9040899DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7230393PMC

Laparoscopy for Hepatolithiasis: Biliary Duct Exploration with Primary Closure Versus T-Tube Drainage.

J Laparoendosc Adv Surg Tech A 2020 Mar 27. Epub 2020 Mar 27.

Department of General Surgery, The Second Affiliated Hospital of Shanxi Medical University, Taiyuan, China.

A recent meta-analysis showed that the primary closure (PC) of the biliary duct in the absence of T-tube (TT) drainage is a safe alternative for cholelithiasis after laparoscopic biliary exploration. However, its feasibility, benefits, and indications in hepatolithiasis remain undefined. From October 2008 to October 2012, we enrolled 84 patients with intrahepatic bile duct stones who underwent laparoscopic bile duct exploration (LBDE) and/or hepatectomy with TT-drainage or PC. Read More

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http://dx.doi.org/10.1089/lap.2020.0081DOI Listing

Gallstone Ileus: An Unusual Cause of Intestinal Obstruction.

Cureus 2020 Mar 15;12(3):e7284. Epub 2020 Mar 15.

Surgery, The Wollongong Hospital, Wollongong, AUS.

Gallstone ileus is an uncommon complication of gallstones and a rare cause of intestinal obstruction. Typically as a result of the formation of cholecystoduodenal fistula, surgical removal of the gallstone is the mainstay of treatment in order to relieve the intestinal obstruction. A 34-year-old male with no history of cholelithiasis presented with features of a small bowel obstruction. Read More

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http://dx.doi.org/10.7759/cureus.7284DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7077742PMC

Schaftoside alleviates HFD-induced hepatic lipid accumulation in mice via upregulating farnesoid X receptor.

J Ethnopharmacol 2020 Jun 20;255:112776. Epub 2020 Mar 20.

School of Pharmaceutical Sciences, Guangzhou University of Chinese Medicine, Guangzhou, 510405, China. Electronic address:

Ethnopharmacology Relevance: The farnesoid X receptor (FXR) is a therapeutic target of for the treatment of non-alcoholic fatty liver disease (NAFLD) owing to its regulatory role in lipid homeostasis. Schaftoside (SS) is a bioactive compound of Herba Desmodii Styracifolii, which has traditionally been used to treat hepatitis and cholelithiasis. However, the potential hepatoprotective effect of SS against NAFLD and the underlying mechanisms remain unknown. Read More

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http://dx.doi.org/10.1016/j.jep.2020.112776DOI Listing

Etiology and mortality in severe acute pancreatitis: A multicenter study in Japan.

Pancreatology 2020 Apr 6;20(3):307-317. Epub 2020 Mar 6.

Department of Emergency Medicine, School of Medicine University of Occupational and Environmental Health, 1-1, Iseigaoka, Yahata Nishi, KitaKyushu, Fukuoka, Japan.

Background/objectives: Severe acute pancreatitis (SAP) has a high mortality rate despite ongoing attempts to improve prognosis through a various therapeutic modalities. This study aimed to delineate etiology-based routes that may guide clinical decisions for the treatment of SAP.

Methods: Using data from a recent retrospective multicenter study in Japan, we analyzed the association between clinical outcomes, mainly in-hospital mortality and pancreatic infection, and various etiologies while considering confounding factors. Read More

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http://dx.doi.org/10.1016/j.pan.2020.03.001DOI Listing

Laparoscopic management of cholecystocolonic fistula: A case report and a brief literature review.

Int J Surg Case Rep 2020 28;68:218-220. Epub 2020 Feb 28.

Department of Surgical, Oncologic and Stomatological Disciplines (Di.Chir.On.S.), University of Palermo, Italy. Electronic address:

Introduction: Cholecystoenteric fistula is a rare and late complication of cholelithiasis. The clinical presentation is mostly chronic and is not distinguishable from the dyspeptic symptoms of non-complicated cholelithiasis. For this reason, the preoperative diagnosis is difficult and uncertain, and it is often made up primarily intraoperatively and incidentally during cholecystectomy. Read More

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http://dx.doi.org/10.1016/j.ijscr.2020.02.052DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7078439PMC
February 2020

Cholecystectomy does not worsen progression or outcomes in non-alcoholic fatty liver disease.

Transl Gastroenterol Hepatol 2020 5;5. Epub 2020 Jan 5.

Division of Gastroenterology and Hepatology, University of South Dakota Sanford School of Medicine and Avera McKennan Hospital, Transplant Institute, Sioux Falls, SD, USA.

Background: Cholecystectomy is a frequently performed surgical procedure for symptomatic cholelithiasis, which is reported to be more common in patients with non-alcoholic steatohepatitis (NASH), given the common risk factors. However, the data remains unclear on the association of cholecystectomy with NASH. We performed a retrospective study to examine the association of cholecystectomy and NASH. Read More

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http://dx.doi.org/10.21037/tgh.2019.09.03DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7061184PMC
January 2020

Beta-Thalassemia Intermedia: A Single Thalassemia Center Experience from Northeastern Iraq.

Biomed Res Int 2020 28;2020:2807120. Epub 2020 Feb 28.

Thalassemia and Congenital Blood Disorders Center, Sulaymaniyah 46001, Iraq.

Objective: To determine the molecular characterization and disease-associated complications of beta-thalassemia intermedia (-TI) patients in Sulaymaniyah province, northeastern Iraq.

Methods: A total of 159 -TI) patients in Sulaymaniyah province, northeastern Iraq. -TI) patients in Sulaymaniyah province, northeastern Iraq. Read More

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http://dx.doi.org/10.1155/2020/2807120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7066418PMC
February 2020

A Modified Suture Technique in Hepaticojejunostomy.

Med Sci Monit 2020 Mar 19;26:e921896. Epub 2020 Mar 19.

Department of Hepatobiliary Surgery, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, Shandong, China (mainland).

BACKGROUND Hepaticojejunostomy is a common biliary reconstruction procedure in hepatobiliary surgery. The suture technique plays a key role in the procedure. The conventional suture technique is complex and time-consuming. Read More

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http://dx.doi.org/10.12659/MSM.921896DOI Listing

An Important Gallbladder Pathology Mimicking Gallbladder Carcinoma: Xanthogranulomatous Cholecystitis: A Single Tertiary Center Experience.

Surg Laparosc Endosc Percutan Tech 2020 Mar 16. Epub 2020 Mar 16.

Ministry of Health, University of Health Science, Kanuni Sultan Süleyman Training and Research Hospital, Istanbul, Turkey.

Background: Xanthogranulomatous cholecystitis (XGC) is an uncommon, focal, or diffuse destructive inflammatory disease of the gallbladder mimicking or being together with the gallbladder carcinoma. This study aimed to evaluate the diagnosis, treatment, and outcomes of patients with XGC as a single tertiary center experience in the light of literature.

Materials And Methods: Data about 34 patients with XGC identified after evaluating 2212 cholecystectomy specimens between January 2013 and December 2018 in a single tertiary center were documented to determine demographics (sex, age), clinical symptoms and findings, biochemical and imaging clues and operative findings, duration of hospitalization, postoperative complications, and histopathologic results. Read More

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http://dx.doi.org/10.1097/SLE.0000000000000781DOI Listing

Dilation of the cystic duct confluence in laparoscopic common bile duct exploration and stone extraction in patients with secondary choledocholithiasis.

BMC Surg 2020 Mar 17;20(1):50. Epub 2020 Mar 17.

Department of Anesthesiology, Shanghai Children's Medical Center, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Background: Many options exist for the management of cholelithiasis and secondary choledocholithiasis. Among them, laparoscopic common bile duct exploration (LCBDE) with choledocotomy followed by laparoscopic cholecystectomy has gained popularity. However, efforts should be made to ensure minimally invasive or noninvasive management of the common bile duct (CBD). Read More

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http://dx.doi.org/10.1186/s12893-020-00705-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7079474PMC
March 2020
1.240 Impact Factor

Cholelithiasis in the Dog: Prevalence, Clinical Presentation, and Outcome.

J Am Anim Hosp Assoc 2020 May/Jun;56(3):152. Epub 2020 Mar 17.

From Small Animal Hospital (P.M.W., K.B., G.H., S.B., M.C., G.N., A.E.R.) and Weipers Centre Equine Hospital (T.P.), University of Glasgow, Glasgow, United Kingdom.

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http://dx.doi.org/10.5326/JAAHA-MS-7000DOI Listing

The utility of digital cholangioscopy (SpyGlass DS) in biliary and pancreatic diseases: A clinical feasibility study at two tertiary care centers in Saudi Arabia (with Videos).

Arab J Gastroenterol 2020 Mar 13;21(1):49-53. Epub 2020 Mar 13.

King Fahad Medical City, Department of Gastroenterology and Hepatology, Riyadh, Saudi Arabia. Electronic address:

Background And Study Aim: Since its inception in 2007, single-operator cholangioscopy (SOC) has gained popularity for many diagnostically and therapeutically challenging biliary and pancreatic conditions. Many studies have been published to evaluate the feasibility, usefulness, cost-effectiveness, and safety profile of the first generation. This paper is a descriptive study in which we aim to share the experience of two tertiary care centers with the novel version of SOC, SpyGlass DS. Read More

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http://dx.doi.org/10.1016/j.ajg.2019.12.003DOI Listing

Management of Middle Hepatic Vein Injury during Laparoscopic Cholecystectomy: A Case Report.

Surg J (N Y) 2020 Jan 9;6(1):e47-e48. Epub 2020 Mar 9.

Department of Metabolic Support and Surgery for Intestinal Failure, Hospital Universitario Fundación Santa Fé de Bogotá, Bogotá, Colombia.

 Cholecystectomy continues to be the first choice for the treatment of symptomatic cholelithiasis. Especially in patients with acute cholecystitis, a laparoscopic approach has become the standard treatment option. Intraoperative complications of laparoscopic cholecystectomy include: bile duct injury, organ damage, and bleeding due to vascular injury. Read More

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http://dx.doi.org/10.1055/s-0040-1701695DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7062551PMC
January 2020

[How I treat... choledocholithiasis by retrograde cholangiopancreatography in a patient with gastric bypass].

Rev Med Liege 2020 Mar;75(3):140-144

Service de Gastroentérologie, CHC Saint-Joseph, Liège, Belgique.

Performing endoscopic retrograde cholangiopancreatography (ERCP) in bariatric patients with gastric bypass is often challenging. Many techniques have been described. Recently, Endoscopic ultrasound (EUS) - direct transgastric ERCP (EDGE) by using lumen-apposing metal stent (LAMS) has shown efficacy to reach biliary orifice and perform conventional ERCP with good safety profile and low risk of adverse events. Read More

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