39,954 results match your criteria Cholelithiasis

Cholecystectomy and bariatric surgery in asymptomatic patients with cholelithiasis?

Jorge de Tomás

Cir Esp (Engl Ed) 2022 May 14. Epub 2022 May 14.

Unidad de Cirugía Esofagogástrica, HGU Gregorio Marañón, Madrid, Spain. Electronic address:

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Biomarkers and Disease Trajectories Influencing Women's Health: Results from the UK Biobank Cohort.

Phenomics 2022 May 12:1-10. Epub 2022 May 12.

Department of Epidemiology and Health Statistics, School of Public Health and Key Laboratory of Ministry of Education for Gastrointestinal Cancer, Fujian Medical University, Xue Yuan Road 1, University Town, Fuzhou, 350122 China.

Women's health is important for society. Despite the known biological and sex-related factors influencing the risk of diseases among women, the network of the full spectrum of diseases in women is underexplored. This study aimed to systematically examine the women-specific temporal pattern (trajectory) of the disease network, including the role of baseline physical examination indexes, and blood and urine biomarkers. Read More

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Relative contribution of susceptibility weighted imaging, compared to conventional MRI, in the detection of common bile-duct calculi.

Diagn Interv Radiol 2022 Mar;28(2):131-137

Fortis Memorial Research Institute, Gurgaon, India.

PURPOSE We aimed to evaluate the relative contribution of susceptibility weighted imaging (SWI) in the detection of common bile-duct (CBD) stones in comparison to the conventional MRI protocol containing magnetic resonance cholangiopancreatography (MRCP), balanced turbo field echo (BTFE), and T2-weighted spin-echo imaging techniques. METHODS MRI data containing MRCP, BTFE, T2-weighted imaging, and abdominal SWI were independently evaluated by 2 sets of experienced radiologists in 44 patients with confirmed CBD stones. Endoscopic retrograde cholangiopancreatography, and endoscopic ultrasound where available, was used as the reference gold standard. Read More

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Patients with Primary and Secondary Bile Duct Stones Harbor Distinct Biliary Microbial Composition and Metabolic Potential.

Front Cell Infect Microbiol 2022 25;12:881489. Epub 2022 Apr 25.

Center for Microbiota and Immunological Diseases, Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Introduction: Cholelithiasis has a high incidence worldwide and limited treatment options due to its poorly understood pathogenesis. Furthermore, the role of biliary microbiota in cholelithiasis remains understudied. To address these questions, we performed microbial sequencing from biliary samples from primary bile duct stone (PBDS) and secondary bile duct stone (SBDS) patients. Read More

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[Diagnostic value of gamma-glutamyl transferase and alkaline phosphatase for cholecystolithiasis complicated with occult pancreaticobiliary reflux].

Zhonghua Yi Xue Za Zhi 2022 May;102(18):1359-1363

Center of Gallbladder Disease, Shanghai East Hospital, Institute of Gallstone Disease, School of Medicine, Tongji University, Shanghai 200120, China.

To explore the diagnostic value of the preoperative liver function for occult pancreaticobiliary reflux (OPBR) in patients with gallstones. Patients with gallstones in Shanghai East Hospital were enrolled from December 2020 to June 2021. Their intraoperative bile and clinical data were collected. Read More

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[Pay attention to endoscopic diagnosis and treatment for confluence disease of pancreaticobiliary ducts].

C Zhang Y L Yang

Zhonghua Yi Xue Za Zhi 2022 May;102(18):1326-1329

Cholelithiasis Center, Tongji University Affiliated Shanghai East Hospital, Shanghai 200120, China.

The confluence of pancreaticobiliary ducts refers to the area between the end of common bile duct, the opening of main pancreatic duct and duodenal papilla. Those confluence diseases of pancreaticobiliary ducts will cause obstruction of biliary and pancreatic outflow tract, cholestasis, pancreatic juice deposition or pancreaticobiliary reflux, and thus induce gallstones, cholangitis, pancreatitis and other diseases. Endoscopic ampullary sphincterotomy is an important way to treat biliary and pancreatic diseases, but the length of incision is determined by the anatomy of Oddi sphincter. Read More

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[Laparoscopic Common Bile Duct Exploration for Treatment of Common Bile Duct Stones:Clinical Analysis of 158 Cases].

Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2022 Apr;44(2):286-289

Department of General Surgery,the Number One Hospital of Zhangjiakou,Zhangjiakou,Hebei 075000,China.

Objective To evaluate the safety and effectiveness of laparoscopic common bile duct exploration in the treatment of common bile duct stones. Methods A retrospective analysis was conducted for 158 patients with cholecystolithiasis and choledocholithiasis admitted to the Number One Hospital of Zhangjiakou from January 2015 to December 2019.The patients were assigned into three groups according to the diameters of cystic duct and common bile duct,degrees of abdominal infection and tissue edema,and operation method. Read More

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Risk factors for gallbladder cancer development in northern India: A gallstones-matched, case-control study.

Indian J Med Res 2021 May;154(5):699-706

Department of Surgical Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India.

Background & Objectives: A high incidence of gallbladder cancer (GBC) is observed in northern India. This study was aimed to identify the factors involved in developing GBC in this region.

Methods: A gallstones-matched, case-control study was conducted in northern India. Read More

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Prevalence of Empyema or Mucocele or Other Histological Diagnoses in Patients Undergoing Cholecystectomy With Diagnosis of Chronic Cholecystitis.

Cureus 2022 Apr 3;14(4):e23773. Epub 2022 Apr 3.

Surgery, Government Hospital Ghaziabad, Lahore, PAK.

Background Chronic cholecystitis is inflammation of the gall bladder usually caused by stones. The aim was to find out the prevalence of mucocele and empyema in chronic cholecystitis using cholecystectomy findings and histopathological reports. Methodology This was a cross-sectional observational study conducted in Surgical Ward 1, Jinnah Postgraduate Medical Center, Karachi from December 2019 to December 2021 for two years. Read More

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A Nomogram-based Model to Predict Neoplastic Risk for Patients with Gallbladder Polyps.

J Clin Transl Hepatol 2022 Apr 30;10(2):263-272. Epub 2021 Jun 30.

Department of Hepato-biliary-pancreatic Surgery, The Affiliated Changzhou No. 2 People's Hospital of Nanjing Medical University, Changzhou, Jiangsu, China.

Background And Aims: Gallbladder polyp (GBP) assessment aims to identify the early stages of gallbladder carcinoma. Many studies have analyzed the risk factors for malignant GBPs. In this retrospective study, we aimed to establish a more accurate predictive model for potential neoplastic polyps in patients with GBPs. Read More

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Gallstone Ileus with Cholecystogastric Fistula in an Older Female.

Eur J Case Rep Intern Med 2022 29;9(4):003345. Epub 2022 Apr 29.

Emergency Medicine Department, Charleston Area Medical Center, Charleston, WV, USA.

Cholecystogastric fistulas are a rare but life-threatening complication of cholelithiasis. This medical condition has been explained in detail in several cases in the medical literature. However, there is still conflicting debate on how well to effectively manage patients with such a complex medical condition. Read More

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The Natural History of Asymptomatic Gallstones: a Longitudinal Study and Prediction Model.

Clin Gastroenterol Hepatol 2022 May 2. Epub 2022 May 2.

Cleveland Clinic Lerner College of Medicine, Case Western Reserve University, Cleveland, OH, USA; Center for Value-Based Care Research, Medicine Institute, Cleveland Clinic, Cleveland, OH, USA. Electronic address:

Background & Aims: Despite the high prevalence of asymptomatic gallstones (AG), there are limited data on their natural history. We aimed to determine the rate of symptom development in a contemporary population; determine factors associated with progression to symptomatic gallstones (SG); and develop a clinical prediction model.

Methods: DESIGN: Retrospective cohort. Read More

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[Prediction model for gallstones can support the general practitioner].

Henk J Schers

Ned Tijdschr Geneeskd 2022 04 14;166. Epub 2022 Apr 14.

Radboud Universitair Medisch Centrum, afd. Eerstelijnsgeneeskunde.

The management of gallstones in primary care is challenging. After diagnosis, the GP has to decide which symptomatic patients will profit from referral for surgery. This is complicated, as many patients will continue to have symptoms also after surgery. Read More

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[Jaundice due to a rare cause: detection through systematic analysis].

Ned Tijdschr Geneeskd 2022 04 6;166. Epub 2022 Apr 6.

Medisch Spectrum Twente, afd. Maag-, Darm en Leverziekten, Enschede.

Background: Jaundice is a clinical symptom as a result of cholestasis. It can be caused by a wide variety of disorders. Its differential diagnosis is broad. Read More

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Cystic fibrosis-related liver disease is an independent risk factor for mortality and increased health care resource utilization in hospitalized pediatric patients with cystic fibrosis.

Pediatr Pulmonol 2022 May 2. Epub 2022 May 2.

Division of Pediatric Gastroenterology, Hepatology and Nutrition, UH Rainbow Babies and Children's Hospital/Case Western Reserve University School of Medicine, Cleveland, Ohio, USA.

Background: Cystic fibrosis-related liver disease (CFLD) is more prevalent in recent decades due to the increasing life expectancy of patients with cystic fibrosis (CF). There is paucity of population-level data on the impact of CFLD on hospital outcomes.

Methods: We interrogated nonoverlapping years (2003-2016) of the National Inpatient Sample and Kids' Inpatient Database to include all hospitalized patients <21 years of age with a primary diagnosis of CF within the United States. Read More

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Laparoscopic Cholecystectomy in a Patient With Situs Inversus Totalis Presenting With Cholelithiasis: A Case Report.

Front Surg 2022 14;9:874494. Epub 2022 Apr 14.

Department of Hepatobiliary Surgery, Chengdu Second People's Hospital, Chengdu, China.

Laparoscopic cholecystectomy is the standard treatment for cholelithiasis. A very rare condition named situs inversus should not be considered as a contraindication for laparoscopic cholecystectomy. Here, we reported a case of successful laparoscopic cholecystectomy in a patient with situs inversus totalis. Read More

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[Perioperative management of laparoscopic cholecystectomy in a patient with paroxysmal nocturnal haemoglobinuria undergoing ravulizumab treatment].

Rinsho Ketsueki 2022 ;63(4):260-264

Department of Hematology, Tokyo Medical and Dental University.

Paroxysmal nocturnal hemoglobinuria (PNH) is characterized by hemolysis, thrombosis, and bone marrow failure. Infection, pregnancy, and surgical operation have the potential to evoke severe episodes of hemolysis and thrombosis. Therefore, the use of an antibody agent against complement component 5 (C5), eculizumab, one day before the operation is recommended. Read More

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Difficult gall bladder in adolescents with cystic fibrosis and symptomatic cholelithiasis: What is the best treatment choice?

J Pediatr Surg 2022 Apr 22. Epub 2022 Apr 22.

Department of Pediatric Surgery and Urology, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy; Chief of Surgical Department, Institute for Maternal and Child Health, IRCCS "Burlo Garofolo", Trieste, Italy.

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Risk Factors for Urgent or Emergent Cholecystectomy Mid-workup for Symptomatic Cholelithiasis.

Am Surg 2022 Apr 29:31348221093535. Epub 2022 Apr 29.

Department of Surgery, 8395Walter Reed National Military Medical Center, Bethesda, MD, USA.

Background: Patients who undergo cholecystectomy often do so for diagnoses related to the sequelae of gallstones. Many patients present acutely, requiring urgent removal due to complications of cholelithiasis. This study aims to characterize the patient population likely to present acutely during ongoing workup for cholelithiasis to better identify those who may benefit from expedited care. Read More

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Analysis of the Relationship Between Periampullary Diverticulum and Recurrent Bile Duct Stones After Endoscopy on Magnetic Resonance Imaging of Magnetic Nanoparticles.

J Biomed Nanotechnol 2022 Feb;18(2):607-615

Department of Hepatobiliary Pancreatic Surgery and Liver Transplantation Center, The First Hospital of Shanxi Medical University, Taiyuan, 030000, China.

The objective of this work was to investigate the effect of magnetic resonance cholangiopancreatography (MRCP) based on super-paramagnetic iron oxide nanoparticles (SPIONs) on the recurrence diagnosis of periampullary diverticulum (PAD) and bile duct stone (BDS), so as to provide a scientific research basis for the recidivation factors of bile duct stones in clinic. Patients with PAD diagnosed in hospital from July 2019 to March 2021 (who had undergone endoscopic gallstone surgery) were selected for study in this work. They were rolled into two groups, the parapapillary group (123 cases) and the cholangiopancreatic duct directly opening in the diverticulum group (97 cases), according to the clinical classification. Read More

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February 2022

Cholecystectomy in the elderly: clinical outcomes and risk factors.

Ann Ital Chir 2022 ;93:160-167

Aim Of The Study: Recent decades have seen a steady increase in the number of elderly patients undergoing cholecystectomy surgery. The objective of this study is to evaluate clinical outcomes in this cohort of patients and to identify any predictive factors correlative with adverse outcomes arising in the postoperative period.

Method: A retrospective study was conducted regarding patients aged ≥65 years who underwent cholecystectomy surgery. Read More

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Endoscopic electrohydraulic lithotripsy treatment of sigmoid bowel obstruction caused by gallstones.

BMJ Case Rep 2022 04 26;15(4). Epub 2022 Apr 26.

Department of Surgery, Zealand University Hospital, Koge, Sjælland, Denmark

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Factors Influencing Gallstone Formation: A Review of the Literature.

Biomolecules 2022 04 6;12(4). Epub 2022 Apr 6.

Department of Neurosurgery, Wayne State University School of Medicine, Detroit, MI 48201, USA.

Gallstone disease is a common pathology of the digestive system with nearly a 10-20% incidence rate among adults. The mainstay of treatment is cholecystectomy, which is commonly associated with physical pain and may also seriously affect a patient's quality of life. Clinical research suggests that cholelithiasis is closely related to the age, gender, body mass index, and other basic physical characteristics of patients. Read More

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Translational Applications of Extracorporeal Shock Waves in Dental Medicine: A Literature Review.

Biomedicines 2022 Apr 14;10(4). Epub 2022 Apr 14.

Department of Prosthetic Dental Sciences, College of Dentistry, King Saud University, Riyadh 11545, Saudi Arabia.

Extracorporeal shock wave therapy (ESWT) has been studied and applied extensively in medical practice for various applications including musculoskeletal, dermal, vascular, and cardiac indications. These indications have emerged from primary ESWT use in treating urolithiasis and cholelithiasis. Likewise, dental medicine has had its share of utilizing ESWT in various investigations. Read More

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Single-stage intraoperative ERCP combined with laparoscopic cholecystectomy versus preoperative ERCP Followed by laparoscopic cholecystectomy in the management of cholecystocholedocholithiasis: A meta-analysis of randomized trials.

Medicine (Baltimore) 2022 Mar 11;101(10):e29002. Epub 2022 Mar 11.

Department of Hepatobiliary Surgery, Zigong First People's Hospital, Zigong, Sichuan, China.

Objectives: The optimal treatment strategy for cholecystocholedocholithiasis is still controversial. We conducted an up-to-date meta-analysis to compare the efficacy and safety of the intra- endoscopic retrograde cholangiopancreatography (ERCP) + LC procedure with the traditional pre-ERCP +  laparoscopic cholecystectomy (LC) procedure in the management of cholecystocholedocholithiasis.

Methods: We searched the PubMed, Embase, Cochrane Library, and Web of Science databases up to September 2020. Read More

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The effectiveness and biosafety of diatrizoate contrast media in complicated cholelithiasis.

Pol Merkur Lekarski 2022 Apr;50(296):102-108

Ternopil V. Hnatiuk National Pedagogical University, Ternopil, Ukraine.

Adverse reactions after intravascular administration of iodine-based contrast media are well-known. Nevertheless the same type of contrast media is also used for endoscopic retrograde cholangiopancreatography and systemic absorption of contrast media after mentioned procedure routinely occurs, not much is known about effects of widely used diatrizoates (Triombrast) on the hepato-pancreato-biliary system in case of cholelithiasis treatment.

Aim: The aim of the present study was to determine the effectiveness and biosafety of diatrizoate contrast media in terms of complicated cholelithiasis healing using conventional and improved surgery treatment protocols based on set of biochemical markers. Read More

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Escitalopram-induced hepatitis: A case report.

World J Clin Cases 2022 Mar;10(8):2468-2473

Department of Pharmacy, Valenciennes Hospital, Valenciennes 59300, France.

Background: The antidepressant escitalopram is widely prescribed for the treatment of depression. It is generally well-tolerated, and cholestasis is not mentioned in its summary of product characteristics (SmPC). We present a case of cholestatic and cytolysis liver injury due to escitalopram and a VigiBase study. Read More

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Microbiologic risk factors of recurrent choledocholithiasis post-endoscopic sphincterotomy.

World J Gastroenterol 2022 Mar;28(12):1257-1271

Guangdong Provincial Key Laboratory of Microbial Safety and Health, Key Laboratory of Agricultural Microbiomics and Precision Application, Ministry of Agriculture and Rural Affairs, State Key Laboratory of Applied Microbiology Southern China, Institute of Microbiology, Guangdong Academy of Sciences, Guangzhou 510070, Guangdong Province, China.

Background: Choledocholithiasis is a severe disorder that affects a significant portion of the world's population. Treatment using endoscopic sphincterotomy (EST) has become widespread; however, recurrence post-EST is relatively common. The bile microbiome has a profound influence on the recurrence of choledocholithiasis in patients after EST; however, the key pathogens and their functions in the biliary tract remain unclear. Read More

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Laparoscopic radical hepatectomy and lymphadenectomy for incidental gallbladder cancer. Surgical technique with ICG fluorescence enhancement.

Surg Oncol 2022 Apr 4;42:101756. Epub 2022 Apr 4.

HPB and Liver Transplant Unit, Department of General Surgery, Clínica Universidad de Navarra, University of Navarra, Av. Pío XII, 36, 31008, Pamplona, Spain; Institute of Health Research of Navarra (IdisNA), C. de Irunlarrea, 3, 31008, Pamplona, Navarra, Spain. Electronic address:

Background: Radical re-resection has been demonstrated beneficial in incidental gallbladder cancer (iGBC) stages ≥ pT1b [1]. Anatomical resection (AR) of segments IVb-V is recommended, particularly for iGBC and liver-sided tumors [2]. Laparoscopically, this is a challenging procedure, as well as the regional lymphadenectomy, since inflammation from previous surgery can hinder identification of extrahepatic bile ducts. Read More

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