18,766 results match your criteria Cholecystitis


The impact of empiric endoscopic biliary sphincterotomy on future gallstone-related complications in patients with non-severe acute biliary pancreatitis whose cholecystectomy was deferred or not performed.

Surg Endosc 2018 Dec 7. Epub 2018 Dec 7.

Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, 10330, Thailand.

Background: Early cholecystectomy (EC) is recommended in patients with acute biliary pancreatitis (ABP). In real-life practice, cholecystectomy is frequently deferred due to various reasons and delayed cholecystectomy (DC) is performed instead. Endoscopic sphincterotomy (ES) is an alternative to prevent recurrent pancreatitis, however other gallstone-related complications (GCs) may still develop. Read More

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December 2018

Detection and monitoring of postinterventional success and complications of the liver using contrast-enhanced ultrasound (CEUS) - a case report after interventional treatment of a giant hemangioma.

Med Ultrason 2018 Dec;20(4):536-538

Department of Radiology, Interdisciplinary Ultrasound-Center Ludwig-Maximilians-University of Munich - Grosshadern Campus, Munich, Germany.

This case report relates the use of contrast-enhanced ultrasound (CEUS) for the assessment and treatment of a postinterventional cholecystitis, a rare but important complication after transcatheter arterial embolization of a giant hemangioma. Regarding the imaging diagnosis, hemangiomas have specific features allowing a fast recognition by all radiological modalities,and in recent years, especially by CEUS. Read More

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December 2018

Positive Murphy's Sign in Pericardial Hematoma from a Right Atrial Tear.

Cureus 2018 Oct 2;10(10):e3402. Epub 2018 Oct 2.

Cardiology, Maricopa Integrated Health System, Phoenix, USA.

A positive Murphy's sign in a patient with right upper quadrant abdominal pain is the arrest of inspiration during deep palpation of the quadrant. It is usually suggestive of acute cholecystitis. We report an unusual case of a positive Murphy's sign not due to acute cholecystitis, but rather from a pericardial hematoma from a right atrial tear causing right heart failure. Read More

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October 2018

[Endogenic antimicrobial peptides and cytokines in calculous cholecystitis].

Khirurgiia (Mosk) 2018 (10):51-54

Azerbaijan Medical University, Baku, Azerbaijan.

Aim: To analyze concentration of some antimicrobial peptides and cytotoxins in acute calculous cholecystitis regarding gallbladder inflammation grade.

Material And Methods: There were 69 patients with catarrhal (29), phlegmonous (24) inflammation and gangrenous phlegmon (19). Some antimicrobial peptides (HNP-α, BPI, endotoxin, neutrophil elastase, lactoferritin, hepcidin) and cytokines (TNF-α, IL-6, 8, 10) in blood serum as well as hepcidin, TNF-α and IL-6 in hepatic biopsy samples were assessed. Read More

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January 2018

Extending the Indication for Laparoscopic Surgery in Patients With Pan-Peritonitis.

Surg Laparosc Endosc Percutan Tech 2018 Dec 10. Epub 2018 Dec 10.

Surgery, Hanyang University Guri Hospital, Hanyang University School of Medicine, Seoul, Korea.

Background: There have been reports of favorable results in patients with peritonitis who underwent laparoscopic surgery. The present study evaluated the outcomes of laparoscopic surgery in patients with pan-peritonitis.

Materials And Methods: We enrolled 148 patients who underwent open and laparoscopic surgery for pan-peritonitis between January 2015 and December 2017 at Hanyang University Guri Hospital. Read More

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December 2018

Pre-surgery age-adjusted Charlson Comorbidity Index is associated with worse outcomes in acute cholecystitis.

Dig Liver Dis 2018 Oct 11. Epub 2018 Oct 11.

Surgery Unit, IRCCS Ospedale Policlinico San Martino, Genoa, Italy.

Background: Beneficial effects of cholecystectomy in acute cholecystitis (AC) might be weakened by complications. The age-adjusted Charlson Comorbidity Index (CCI) assesses disease relevance in the prediction of one-year mortality.

Aims: To evaluate whether age-adjusted CCI predicted complications (including surgical complications, intensive care unit [ICU] admission, and in-hospital death) among patients undergoing cholecystectomy for AC. Read More

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October 2018

The efficacy and safety of tazobactam/ceftolozane in combination with metronidazole in Japanese patients with complicated intra-abdominal infections.

J Infect Chemother 2018 Dec 5. Epub 2018 Dec 5.

Japan Development, MSD K.K., Tokyo, Japan. Electronic address:

Tazobactam/ceftolozane, a novel antimicrobial therapy, is active against Pseudomonas aeruginosa and most extended-spectrum β-lactamase (ESBL)-producing Enterobacteriaceae. We report the results of the efficacy and safety of tazobactam/ceftolozane in Japanese patients with complicated intra-abdominal infections (cIAI). A multicenter, open-label, noncomparative study (MK-7625A Protocol 013, ClinicalTrials. Read More

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December 2018

Characteristics and Timing of Interhospital Transfers of Emergency General Surgery Patients.

J Surg Res 2019 Jan 26;233:8-19. Epub 2018 Jul 26.

Department of Surgery, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin.

Background: Transferred emergency general surgery (EGS) patients have increased morbidity, mortality, and costs, yet little is known about the characteristics of such transfers. Increasing specialization and a decreasing general surgery workforce have led to concerns about access to care, which may lead to increased transfers. We sought to evaluate the reasons for and timing of transfers for EGS diagnoses. Read More

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January 2019
1 Read

Predictors of 30 Day Readmission Following Percutaneous Cholecystostomy.

J Surg Res 2019 Jan 26;233:1-7. Epub 2018 Jul 26.

Department of Surgery, Yale School of Medicine, New Haven, Connecticut. Electronic address:

Background: High-risk patients undergoing cholecystectomy may experience increased morbidity and mortality. Percutaneous cholecystostomy (PC) has been utilized as a treatment option for acute cholecystitis in this cohort. Little is known about risk factors for readmission following PC. Read More

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January 2019
1 Read

Clinical Outcomes of Elective Laparoscopic Cholecystectomy: Retrospective Comparative Study Between Patients With and Without Xanthogranulomatous Cholecystitis.

Surg Laparosc Endosc Percutan Tech 2018 Dec 3. Epub 2018 Dec 3.

Department of Surgery, University Hospital of Pontevedra, Pontevedra, Spain.

Aim: The aim of this study was to evaluate the results of laparoscopic cholecystectomy (LC) in patients with xanthogranulomatous cholecystitis (XGC) compared with patients without XGC.

Methods: A retrospective study was performed including patients who had undergone elective LC between January 2003 and November 2017. Results of patients with XGC (25) were compared with those of patients without XGC (2181) with respect to operative time, conversion rate, drain use, postoperative complications, and postoperative stay. Read More

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December 2018
1 Read

Outcomes of emergency abdominal surgery in octogenarians: A single-center analysis.

Am J Surg 2018 Nov 27. Epub 2018 Nov 27.

Department of Visceral Surgery and Medicine, Inselspital, Bern University Hospital, University of Bern, Switzerland. Electronic address:

Background: The aim of this study was to assess outcomes of octogenarians undergoing emergency abdominal surgery (EAS).

Methods: Octogenarians undergoing EAS 12/2011-12/2016 were retrospectively analysed. The outcomes were assessed by univariable and multivariable regression analysis. Read More

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November 2018
1 Read

Acute cholecystitis - a cohort study in a real-world clinical setting (REWO study, NCT02796443).

Pragmat Obs Res 2018 25;9:69-75. Epub 2018 Oct 25.

Department of Visceral and Thoracic Surgery, Asklepios Klinik Langen, Langen, Germany,

Background: For decades, the optimal timing of surgery for acute cholecystitis has been controversial. Recent meta-analyses and population-based studies favor early surgery. One recent large randomized trial has demonstrated that a delayed approach increases morbidity and cost compared to early surgery within 24 hours of hospital admission. Read More

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October 2018
3 Reads

Acute Acalculous Cholecystitis in a Previously Healthy Infant

Authors:
A Jenkinson

Ir Med J 2018 May 10;111(5):763. Epub 2018 May 10.

Department of General Paediatrics OLCHC, Crumlin Road, Crumlin, Dublin

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May 2018
1 Read

Importance of routine histopathological examination of a gallbladder surgical specimen: Unexpected gallbladder cancer.

J Cancer Res Ther 2018 Oct-Dec;14(6):1325-1329

Department of General Surgery, Faculty of Medicine, Adıyaman University, Adıyaman, Turkey.

Introduction: Cholecystectomy performed for benign diseases of the gallbladder is important for the diagnosis of gallbladder cancer. This is done by pathological examination of the removed specimens for patients with no detected or suspected complications before surgery. Although some centers undertake selective approaches for histopathological examination of gallbladder specimens, many centers perform this examination routinely. Read More

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November 2018
4 Reads

Acute acalculous cholecystitis in children.

World J Gastroenterol 2018 Nov;24(43):4870-4879

Department of Medicine, School of Medicine, Nazarbayev University, Astana 010000, Kazakhstan.

Acute acalculous cholecystitis (AAC) is the inflammatory disease of the gallbladder in the absence of gallstones. AAC is estimated to represent at least 50% to 70% of all cases of acute cholecystitis during childhood. Although this pathology was originally described in critically ill or post-surgical patients, most pediatric cases have been observed during several infectious diseases. Read More

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November 2018
5 Reads

Situs Inversus Totalis: Laparoscopic Cholecystectomy and Some Modifications.

Mymensingh Med J 2018 Oct;27(4):872-878

Professor Dr Md Kamruzzaman Khan, Professor Department of Surgery, Dhaka Community Medical College and Hospital, Dhaka, Bangladesh.

Laparoscopic cholecystectomy has become the standard approach since its introduction in 1987 by Mouret. Situs inversus totalis is a rare anomaly in which transposition of the organ to the opposite site of the body occurs. Laparoscopic cholecystectomy due to gall stone disease in such few cases has been reported in the literature. Read More

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October 2018
1 Read

Same-admission versus delayed cholecystectomy for mild acute biliary pancreatitis: a systematic review and meta-analysis.

BMC Surg 2018 Nov 29;18(1):111. Epub 2018 Nov 29.

Department of Hepatobiliary Surgery, Dongyang People's Hospital, 60 West Wuning Road, 322100, Dongyang, Zhejiang, China.

Background: The timing of laparoscopic cholecystectomy (LC) performed after the mild acute biliary pancreatitis (MABP) is still controversial. We conducted a review to compare same-admission laparoscopic cholecystectomy (SA-LC) and delayed laparoscopic cholecystectomy (DLC) after mild acute biliary pancreatitis (MABP).

Methods: We systematically searched several databases (PubMed, EMBASE, Web of Science, and the Cochrane Library) for relevant trials published from 1 January 1992 to 1 June 2018. Read More

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November 2018
1 Read

Infectious Complications in Critically Ill Liver Failure Patients.

Semin Respir Crit Care Med 2018 Oct 28;39(5):578-587. Epub 2018 Nov 28.

Division of Infectious Diseases, Department of Medicine, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Infections remain a leading cause of morbidity and mortality among patients with liver failure. A number of factors, including relative immune dysfunction and systemic inflammation, bacterial translocation, gut dysbiosis, small intestine bacterial overgrowth, altered bile acid pools, and changes in pH due to acid suppression, contribute to the high rates of infection in this population. Though a range of infections can complicate the course of cirrhotic patients, spontaneous bacterial peritonitis (SBP), cholangitis, and cholecystitis in addition to other infections (i. Read More

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October 2018
4 Reads

Surgical ultrasonography at the bedside: a comparison of surgical trainees with trained sonographers for symptomatic cholelithiasis - a first Australian experience.

ANZ J Surg 2018 Nov 28. Epub 2018 Nov 28.

Upper Gastrointestinal Surgery Unit, Liverpool Hospital, Sydney, New South Wales, Australia.

Background: Symptomatic cholelithiasis accounts for a significant burden of emergency general surgical presentations in Australia and the Western population. Access to hepatobiliary ultrasonography to facilitate diagnosis can lead to delays in timely treatment. Surgical ultrasonography at the bedside (SUB) can mitigate this barrier to patient care. Read More

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November 2018
1 Read

Bacteriological profile of intra-abdominal infections in a tertiary care hospital.

Iran J Microbiol 2018 Aug;10(4):208-214

Nizam's Institute of Medical Sciences Panjagutta, Hyderabad, Telangana, India.

Background And Objectives: Intra-abdominal infections (IAIs) include a wide spectrum of pathological conditions, ranging from uncomplicated appendicitis to fecal peritonitis .The resulting infections should be diagnosed early and treated based on the organism isolated and its susceptibility. In this study the bacteriological profile and antimicrobial resistance pattern of intra-abdominal infections was analyzed. Read More

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August 2018
4 Reads

Comet tail artifact on ultrasonography: is it a reliable finding of benign gallbladder diseases?

Ultrasonography 2018 Oct 3. Epub 2018 Oct 3.

Department of Radiology, Eulji University Hospital, Daejeon, Korea.

Purpose: The aim of this study was to evaluate whether the comet tail artifact on ultrasonography can be used to reliably diagnose benign gallbladder diseases.

Methods: This retrospective study reviewed the clinical findings, imaging findings, preoperative ultrasonographic diagnoses, and pathological diagnoses of 150 patients with comet tail artifacts who underwent laparoscopic cholecystectomy with pathologic confirmation. The extent of the involved lesion was classified as localized or diffuse, depending on the degree of involvement and the anatomical section of the gallbladder that was involved. Read More

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October 2018
5 Reads

Cholecystectomy following percutaneous cholecystostomy tube placement leads to higher rate of CBD injuries.

Surg Endosc 2018 Nov 26. Epub 2018 Nov 26.

Division of Bariatric, Foregut and Advanced Gastrointestinal Surgery, Department of Surgery, Stony Brook University Medical Center, 100 Nichols Road, HSC T19, Stony Brook, NY, 11794, USA.

Introduction: Percutaneous cholecystostomy tube (PCT) placement is often the management of severe acute cholecystitis in the unstable patient. PCT can be later reversed and cholecystectomy performed. The purpose of this study is to investigate the incidence of subsequent cholecystectomy and clinical factors associated with subsequent procedure. Read More

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November 2018
6 Reads

Typhoid fever complicated by cholecystitis in a 10-year-old boy.

J Paediatr Child Health 2018 Nov 25. Epub 2018 Nov 25.

Department of Infectious Disease, Royal Hobart Hospital, Hobart, Tasmania, Australia.

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November 2018
1 Read

Gallbladder volvulus-acute cholecystitis 'with a twist'.

Authors:
James Aljoe

J Surg Case Rep 2018 Nov 19;2018(11):rjy303. Epub 2018 Nov 19.

General Surgery, Manly Hospital, 150 Darley Road Manly Sydney, Manly, New South Wales, Australia.

A Caucasian 92-year-old female was admitted to hospital with acute epigastric pain associated with vomiting. Initial investigations revealed mildly raised inflammatory markers, normal liver function tests but a markedly distended gallbladder with prominent wall thickening. The patient was managed with intravenous antibiotics for acute cholecystitis but deteriorated significantly on Day 2 of admission. Read More

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November 2018
1 Read

Preoperative endoscopic retrograde cholangio-pancreatography (ERCP) is a risk factor for surgical site infections after laparoscopic cholecystectomy.

Am J Surg 2018 Sep 29. Epub 2018 Sep 29.

Department of Surgery, Massachusetts General Hospital, Boston, MA, USA. Electronic address:

Background: We sought to examine whether preoperative endoscopic retrograde cholangio-pancreatography (ERCP) increases the risk of surgical site infections (SSI) after laparoscopic cholecystectomy.

Methods: Patients admitted to an academic hospital from 2010 to 2016, who were older than 18 and had a laparoscopic or a laparoscopic converted to open cholecystectomy for complicated biliary tract disease were included. We compared those who had a preoperative ERCP to those who did not. Read More

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September 2018

A case report of epiploic appendagitis as a mimic of acute cholecystitis.

Int J Surg Case Rep 2018 Nov 13;53:327-329. Epub 2018 Nov 13.

NHS Western Isles, Western Isles Hospital, Macaulay Road, Stonorway, HS12AF, United Kingdom. Electronic address:

Introduction: Epiploic appendagitis is a rare cause of acute abdominal pain. It's presentation often mimics other causes of acute abdominal pain. It is important for clinicians to be aware of an epiploic appendagitis since a delay in diagnosis can lead to unnecessary hospital stay, antibiotic usage and surgical intervention [1-4]). Read More

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November 2018
9 Reads

Tokyo Guidelines for the Diagnosis of Acute Cholecystitis.

J Am Coll Surg 2018 Dec;227(6):624

St Louis, MO.

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December 2018
6 Reads

Preoperative Predictors of Choledocholithiasis in Patients Presenting with Acute Calculous Cholecystitis.

Gastrointest Endosc 2018 Nov 19. Epub 2018 Nov 19.

University of Michigan Health Care System; VA Healthcare System, Ann Arbor Michigan.

Background And Aims: Markedly elevated liver chemistries in patients presenting with acute calculous cholecystitis (AC) often prompt an evaluation for concomitant choledocholithiasis (CDL). However, current guidelines directing the workup for CDL fail to address this unique population. The aims of this study are to define the range of presenting lab values and imaging findings in AC, develop a model to predict the presence of concurrent CDL, and develop a management algorithm that can be easily applied on presentation. Read More

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November 2018
3 Reads

Percutaneous Cholecystostomy in Acute Cholecystitis-Predictors of Recurrence and Interval Cholecystectomy.

J Surg Res 2018 Dec 3;232:539-546. Epub 2018 Aug 3.

Department of Surgery, Lahey Hospital and Medical Center, Burlington, Massachusetts.

Background: Percutaneous cholecystostomy (PC) tube is a preferred option in acute cholecystitis for patients who are high risk for cholecystectomy (CCY). There are no evidence-based guidelines for patient care after PC. We identified the predictors of disease recurrence and successful interval CCY. Read More

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December 2018
2 Reads

Unnecessary abdominal interventions in patients with hereditary angioedema.

J Dtsch Dermatol Ges 2018 Dec 21;16(12):1443-1449. Epub 2018 Nov 21.

Department of Oto-Rhino-Laryngology Head and Neck Surgery, Ulm University Medical Center, Germany.

Background: Hereditary angioedema (HAE) is a rare genetic disorder that leads to recurrent development of mucosal and dermal swelling. It is mediated by bradykinin, and can affect virtually any part of the human body, including the gastrointestinal tract, the extremities, and the laryngeal and pharyngeal regions. Safe and potent drugs are available for acute and prophylactic treatment of HAE. Read More

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December 2018
7 Reads

Results of laparoscopic cholecystectomy in the elderly.

Rev Col Bras Cir 2018 Nov 14;45(5):e2020. Epub 2018 Nov 14.

Universidade Federal do Paraná, Departamento de Cirurgia, Curitiba, PR, Brasil.

Objective: to evaluate the results of laparoscopic cholecystectomy in the elderly compared with younger patients.

Methods: we retrospectively reviewed computerized medical records of all patients who underwent laparoscopic cholecystectomy for chronic or acute cholecystitis from January 1, 2011 to March 31, 2018 at a single teaching hospital. We stratified the patients into two groups: elderly (≥60 years of age) and younger (<60 years of age). Read More

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November 2018
5 Reads

Biliary Taeniasis with Cholecystitis: An Unusual Case of Infection with a Literature Review.

Am J Trop Med Hyg 2018 Nov 19. Epub 2018 Nov 19.

Department of Laboratory Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea.

Taeniasis is a cosmopolitan helminthic disease caused by species, which included , , and . These parasites typically infect the small intestine, but cases of aberrant migration have been reported. We treated a 70-year-old man who presented with vomiting and colicky abdominal pain. Read More

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November 2018
7 Reads

Postoperative myxedema coma in patients undergoing major surgery: Case series.

Auris Nasus Larynx 2018 Nov 16. Epub 2018 Nov 16.

Department of Otolaryngology, Head & Neck and Maxillofacial Surgery, Tel Aviv Sourasky Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objective: Myxedema coma is a serious complication of hypothyroidism that can be precipitated by major surgery. It is extremely rare, with only a few reports in the literature. This study aims to present a relatively large case series of post-surgical myxedema coma and to analyze medical and surgical risk factors. Read More

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November 2018
5 Reads

Use of retrieval bag in the prevention of wound infection in elective laparoscopic cholecystectomy: is it evidence-based? A meta-analysis.

BMC Surg 2018 Nov 19;18(1):102. Epub 2018 Nov 19.

Department of Surgery, Ospedale Regionale di Bellinzona e Valli, Bellinzona, Switzerland.

Background: Surgical site infections complicate elective laparoscopic cholecystectomies in 2,4-3,2% of cases. During the operation the gallbladder is commonly extracted with a retrieval bag. We conducted a meta-analysis to clarify whether its use plays a role in preventing infections. Read More

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November 2018
2 Reads

Outcomes of Laparoscopic Cholecystectomy in Patients Supported with a Left Ventricular Assist Device.

J Laparoendosc Adv Surg Tech A 2018 Nov 16. Epub 2018 Nov 16.

5 Division of Acute Care Surgery, Department of Surgery, Duke University Medical Center , Durham, North Carolina.

Background: An increasing number of end-stage heart failure patients are supported with left ventricular assist device (LVAD) implantation and must be maintained on consistent anticoagulation. These patients are experiencing prolonged survival and, in some, there is development of new biliary disease. However, safety and outcomes of this procedure in this unique patient group is not well reported. Read More

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November 2018
8 Reads

An Unusual Case of Acute Cholecystitis with Amyloidosis: A Case Report and Literature Review.

Intern Med 2018 Nov 19. Epub 2018 Nov 19.

Department of Gastroenterology, Kyoto City Hospital, Japan.

We present an extremely rare case of amyloid A (AA) deposition in the gallbladder and review the literature on similar cases. The patient was a 76-year-old man who had been diagnosed with mild bronchiectasis three years previously, who was admitted to the hospital with right upper quadrant pain and fever. Computed tomography revealed swelling and wall thickening of the gallbladder with a small gallstone. Read More

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November 2018
4 Reads

Cholecystokinin secretion is suppressed by glucagon-like peptide-1: clue to the mechanism of the adverse gallbladder events of GLP-1-derived drugs.

Scand J Gastroenterol 2018 Nov 19:1-4. Epub 2018 Nov 19.

f Department of Endocrinology, Bispebjerg Hospital , University of Copenhagen , Copenhagen , Denmark.

Objective: Recent randomized and controlled trials of drugs derived from the gut hormone glucagon-like peptide-1 (GLP-1) show that the most frequent adverse symptoms are gastrointestinal, including gallbladder-related side effects such as cholithiasis and cholecystitis. Since the gut hormone cholecystokinin (CCK) stimulates bile secretion and regulates gallbladder motility and emptying, we examined the effect of GLP-1 on the secretion of CCK in normal subjects and patients with type 1 diabetes mellitus.

Materials And Methods: Plasma was sampled from 10 healthy subjects and 10 patients with diabetes. Read More

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November 2018
8 Reads

Subtotal cholecystectomy versus cholecystostomy.

Rev Esp Enferm Dig 2018 Nov 19;111. Epub 2018 Nov 19.

General Surgery, Warrington Hospital, United Kingdom.

Emergency laparoscopic cholecystectomy (LC) is associated with a higher morbidity and mortality, as compared to elective LC. A two-fold increase in 30-day re-admission after LC was associated with two or more pre-operative admissions with symptoms of cholecystitis, as opposed to index-admission-LC (IALC). This was presumably because of more inflammation due to repeated attacks of cholecystitis in the former cohort, making gallbladders more "difficult". Read More

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November 2018
2 Reads

Fibrin sealant agents: clinical application of TachoSil® in abdominal surgery. Six years experience in an emergency surgery department and review of the literature.

G Chir 2018 Sep-Oct;34(5):326-330

Background: The success of every surgical procedure depends on an appropriate hemostatis. Topical haemostatic agents, like fibrin sealants, are an option for providing haemostasis and may be particularly useful for complex injuries.

Aim: The aim of the study is to evaluate the use of TachoSil® in abdominal surgery and its benefits to prevent bleedings, and to establish its fields of use. Read More

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November 2018
5 Reads

Acute Hepatitis B with Pancreatitis and Cholecystitis Leading to Acute Liver Failure and Death.

Clin Pract Cases Emerg Med 2018 Nov 15;2(4):304-308. Epub 2018 Aug 15.

Georgetown University Hospital, Department of Emergency Medicine, Washington, District of Columbia.

Acute liver failure is defined as severe acute liver injury, concurrent with encephalopathy and loss of hepatic synthetic function, in a patient without known pre-existing liver disease. Evaluation of acute liver failure in the emergency department should focus on identification of treatable causes. Acute liver failure from acute hepatitis B infection is a rare but potentially lethal occurrence. Read More

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November 2018
6 Reads

Immune Response to Opisthorchis viverrini Infection and Its Role in Pathology.

Adv Parasitol 2018 10;102:73-95. Epub 2018 Sep 10.

School of Public Health and Social Work, Faculty of Health, Queensland University of Technology, Brisbane, QLD, Australia.

Human liver fluke infection caused by Opisthorchis viverrini is a major public health problem in Mekong countries such as Thailand, Laos, Cambodia, Vietnam, and Myanmar with over 10 million infected through consumption of fish containing infective metacercariae. With no tissue migration phase and living entirely within the larger secondary (intrahepatic) bile ducts, liver flukes are only exposed to a biliary mucosal immune response, while their excretory and secretory products also stimulate chronic inflammation of biliary epithelium. Neither mucosal nor tissue immune responses appear to cause parasite death or protect against newly established flukes, as evidenced by the persistence of infection for decades in the body and rapid reinfection following treatment. Read More

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September 2018
4 Reads

[Radiologic diagnosis of the gallbladder and bile ducts - part 2 : Acute and chronic cholecystitis, primary sclerosing cholangitis (PSC), benign and malignant masses of the biliary system].

Radiologe 2018 Dec;58(12):1099-1114

Kinderradiologie im Dr. von Haunerschen Kinderspital der Radiologischen Klinik und Poliklinik, Ludwig-Maximilian-Universität München, München, Deutschland.

Upper abdominal pain, icterus and cholestasis are the symptoms leading to evaluation of the biliary tract. Together with its complications biliary stone disease is the main reason for inflammation of the biliary system. A distinction is made between acute and chronic variants. Read More

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December 2018
2 Reads

Learning from tragedy: the Julia Berg story.

Diagnosis (Berl) 2018 11;5(4):257-266

Department of Pathology, Yale School of Medicine, New Haven, CT, USA.

This is a case report involving diagnostic errors that resulted in the death of a 15-year-old girl, and commentaries on the case from her parents and involved providers. Julia Berg presented with fatigue, fevers, sore throat and right sided flank pain. Based on a computed tomography (CT) scan that identified an abnormal-appearing gall bladder, and markedly elevated bilirubin and "liver function tests", she was hospitalized and ultimately underwent surgery for suspected cholecystitis and/or cholangitis. Read More

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November 2018
9 Reads

() bloodstream infection following acute cholecystitis.

IDCases 2018 28;14:e00461. Epub 2018 Oct 28.

Department of Anesthesiology, Intensive Care Medicine and Pain Medicine, Saarland University Medical Center, University of Saarland, Homburg, Saar, Germany.

(formerly ) is an anaerobic gram positive rod shaped bacterium belonging to the family of and a common member of the human gut microbiome. However, it is very rarely isolated from clinical human specimens, so data about its clinical significance are scarce. Here we report of a bloodstream infection due to following gangrenous cholecystitis in a 69 year old man. Read More

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October 2018
2 Reads

Perforated emphysematous cholecystitis and Streptococcus bovis.

Rev Esp Enferm Dig 2018 Nov 13;111. Epub 2018 Nov 13.

Cirugía General y del Aparato Digestivo, Hospital Universitario de La Princesa, España.

Streptococcus bovis is an uncommon cause of biliary tract infection, being acute cholecystitis including this microorganism extremely rare. This entity is more frequent in older patients with cardiovascular disease, diabetes, hepatitis, or neoplasms as colon cancer. Read More

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November 2018
2 Reads

Metastatic Cecal Adenocarcinoma to the Gallbladder Presenting with Acute Cholecystitis.

Case Rep Oncol Med 2018 21;2018:5308585. Epub 2018 Oct 21.

Department of Pathology, King Fahad Specialist Hospital, Dammam, Saudi Arabia.

Colorectal cancer (CRC) is one of the most common cancers and the second highest cause of cancer-related deaths (Jemal et al., 2011). Common presentations of CRC include alterations in bowel habit, weight loss, and lower gastrointestinal bleeding. Read More

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October 2018
26 Reads

Bariatric Surgery Did Not Increase the Risk of Gallstone Disease in Obese Patients: a Comprehensive Cohort Study.

Obes Surg 2018 Nov 11. Epub 2018 Nov 11.

Department of General Surgery, Buddhist Dalin Tzu Chi Hospital, No.2, Minsheng Rd., Dalin Township, Chiayi County, 622, Taiwan.

Purpose: The aim of this study was to evaluate the influence of bariatric surgery on gallstone disease in obese patients.

Materials And Methods: This large cohort retrospective study was conducted based on the Taiwan National Health Insurance Research Database. All patients 18-55 years of age with a diagnosis code for obesity (ICD-9-CM codes 278. Read More

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November 2018
7 Reads

Ductopenia and cirrhosis in a 32-year-old woman with progressive familial intrahepatic cholestasis type 3: A case report and review of the literature.

World J Gastroenterol 2018 Nov;24(41):4716-4720

Department of Hepatology, The Third Hospital of Zhenjiang Affiliated Jiangsu University, Zhenjiang 212003, Jiangsu Province, China.

Progressive familial intrahepatic cholestasis type 3 is caused by a mutation in the ATP-binding cassette, subfamily B, member 4 () gene encoding multidrug resistance protein 3. A 32-year-old woman with a history of acute hepatitis at age 9 years was found to have jaundice during pregnancy in 2008, and was diagnosed as having intrahepatic cholestasis of pregnancy. In 2009, she underwent cholecystectomy for gallstones and chronic cholecystitis. Read More

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November 2018
3 Reads

Cancel that PICC line order; cholecystostomy tube and short course of antibiotics.

Am J Surg 2018 Oct 29. Epub 2018 Oct 29.

Geisinger Medical Center, USA.

Background: Current guidelines do not specifically address optimal antibiotic duration following cholecystostomy. This study compares outcomes for short-course (<7 days) and long-course (≥7 days) antibiotics post-cholecystostomy.

Methods: This was a retrospective review of cholecystostomy patients (≥18 years) admitted (1/1/2007-12/31/2017) to one healthcare system. Read More

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October 2018
2 Reads

Emergency presentations of acute biliary pain: changing patterns of management in a tertiary institute.

ANZ J Surg 2018 Dec 9;88(12):1337-1342. Epub 2018 Nov 9.

HPB and Transplant Unit, Austin Hospital, Melbourne, Victoria, Australia.

Background: Acute biliary pain is the most common presentation of gallstone disease. Untreated patients risk recurrent pain, cholecystitis, obstructive jaundice, pancreatitis and multiple hospital presentations. We examine the outcome of implementing a policy to offer laparoscopic cholecystectomy on index presentation to patients with biliary colic in a tertiary hospital in Australia. Read More

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December 2018
9 Reads