1,761 results match your criteria Choanal Atresia


[Clinical research on surgical treatment of benign lesions in maxillary sinus by modified prelacrimal duct recess approach].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Dec;32(24):1847-1850

Department of Otolaryngology Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, and Key Laboratory of Otolaryngology Head and Neck Surgery(Capital Medical University), Ministry of Education, Beijing, 100730, China.

To explore the clinical effects, surgical procedure and indications of surgical treatment for benign lesions in maxillary sinus through modified prelacrimal duct recess approach. All 21 patients in this study who diagnosed with benign lesions in maxillary sinus, received routine preoperational exam and underwent endoscopic maxillary sinus surgery through modified prelacrimal duct recess approach. Postoperatively patients received routine medical treatment, and regular follow-up for average 11. Read More

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December 2018
1 Read

Completely Endoscopic Approach Using a Skeeter Drill to Treat Bilateral Congenital Choanal Atresia in a 33 Week Born Pre-term Baby.

Indian J Otolaryngol Head Neck Surg 2018 Dec 4;70(4):608-610. Epub 2018 Jun 4.

3Care Hospitals, Hyderabad, India.

Choanal atresia (CA) is a relatively rare condition manifesting with respiratory distress. Endoscopic approaches have superseded transnasal and transpalatal approaches. We present a case of a premature baby of 1. Read More

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December 2018
5 Reads

Unmasking familial CPX by WES and identification of novel clinical signs.

Am J Med Genet A 2018 Nov 21:e40630. Epub 2018 Nov 21.

Human Molecular Genetics, de Duve Institute, University of Louvain, Brussels, Belgium.

Mutations in the T-Box transcription factor gene TBX22 are found in X-linked Cleft Palate with or without Ankyloglossia syndrome (CPX syndrome). In addition to X-linked inheritance, ankyloglossia, present in the majority of CPX patients, is an important diagnostic marker, but it is frequently missed or unreported, as it is a "minor" feature. Other described anomalies include cleft lip, micro and/or hypodontia, and features of CHARGE syndrome. Read More

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November 2018
1 Read

SPINT2 (HAI-2) missense variants identified in congenital sodium diarrhea/tufting enteropathy affect the ability of HAI-2 to inhibit prostasin but not matriptase.

Hum Mol Genet 2018 Nov 15. Epub 2018 Nov 15.

Department of Pediatrics I, Medical University of Innsbruck, Innsbruck, Austria.

The syndromic form of congenital sodium diarrhea (SCSD) is caused by bi-allelic mutations in SPINT2, which encodes a Kunitz type serine protease inhibitor (HAI-2). We report three novel SCSD patients, two novel SPINT2 mutations, and review published cases. The most common findings in SCSD patients were choanal atresia (20/34), and keratitis of infantile onset (26/34). Read More

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November 2018
6 Reads

Choanal polyps in children and adults: 10-year experience from a tertiary care hospital.

Eur Arch Otorhinolaryngol 2018 Nov 14. Epub 2018 Nov 14.

Institute for Pathology, Military Medical Academy Faculty of Medicine, Belgrade, Serbia.

Purpose: Choanal polyps (CPs) are benign, solitary, soft-tissue lesions extending towards the junction between the nasal cavity and the nasopharynx through the choana. The aim of this retrospective study was to evaluate clinical and histological characteristics of CPs in children comparing to adult patients.

Methods: Characteristics of CPs treated in our hospital (demography, main complaints, side, localization, surgical approach, histological characteristics, accompanying paranasal sinus diseases, association with allergic rhinitis, postoperative follow-up period, and recurrence rates) were retrospectively reviewed. Read More

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November 2018
2 Reads

Familial congenital choanal atresia with GATA3 associated hypoparathyroidism-deafness-renal dysplasia syndrome unidentified on auditory brainstem response.

Auris Nasus Larynx 2018 Nov 2. Epub 2018 Nov 2.

Shizuoka Prefectural Hospital Organization, Department of Medical Genetics, Shizuoka, Japan.

Hypoparathyroidism-deafness-renal dysplasia (HDR) syndrome is a rare autosomal dominant disorder primarily caused by GATA3 haploinsufficiency and is challenging to diagnose in early childhood. We report a Japanese family with HDR syndrome and congenital choanal atresia. The 6-year-old female proband was diagnosed with epilepsy at the age of three. Read More

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November 2018
8 Reads

Choanal Atresia and Other Neonatal Nasal Anomalies.

Clin Perinatol 2018 Dec 18;45(4):751-767. Epub 2018 Sep 18.

Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins School of Medicine, 601 North Caroline Street, Room 6161B, Baltimore, MD 21287, USA.

Congenital nasal deformities can cause nasal obstruction with early respiratory distress. Choanal atresia is characterized by no communication between the nasal cavity and nasopharynx. Pyriform aperture stenosis involves more anterior nasal obstruction with limited intranasal space. Read More

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December 2018
8 Reads

Phenotypic spectrum of CHARGE syndrome based on clinical characteristics

Turk J Med Sci 2018 Oct 31;48(5):911-915. Epub 2018 Oct 31.

Background/aim: CHARGE syndrome is a rare autosomal dominant disease with multiple congenital anomalies and cognitive impairment, which is caused by mutations in the CHD7 gene. This study aimed to disclose the mild end of the phenotypic spectrum of CHARGE syndrome, which has a highly variable expressivity. Materials and methods: Twenty-one patients who had at least one of the major symptoms of CHARGE syndrome (coloboma, choanal atresia, characteristic ear anomalies, semicircular canal hypoplasia, and cranial nerve anomalies) were included in the study. Read More

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October 2018
4 Reads

Skull base anatomy and surgical safety in isolated and CHARGE-associated bilateral choanal atresia.

Int J Pediatr Otorhinolaryngol 2018 Dec 14;115:61-64. Epub 2018 Sep 14.

Department of Otolaryngology, Royal Children's Hospital Melbourne, Parkville, Victoria, Australia; Murdoch Children's Research Institute, University of Melbourne, Victoria, Australia.

Introduction: Bilateral choanal atresia (BCA) is associated with a high incidence of congenital abnormalities that include skull base anomalies and defects. Surgical repair of BCA is necessary in the early neonatal period and any altered anatomy of the adjacent skull base will heighten the risk of intracranial injury. This risk may be further increased in patients with CHARGE syndrome. Read More

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December 2018
8 Reads

Gross morphological and ultrastructural characterization of the oropharyngeal cavity of the Eurasian hoopoe captured from Egypt.

Anat Sci Int 2018 Oct 24. Epub 2018 Oct 24.

Department of Anatomy and Embryology, Faculty of Veterinary Medicine, Kafrelsheikh University, Kafrelsheikh, 33516, Egypt.

The present study aimed to give full morphological insight into the oropharyngeal cavity of Eurasian hoopoe at the level of gross morphology in addition to ultrastructural inspection including light- and scanning electron microscopy. The oropharyngeal cavity has a triangular appearance with a very long rostrally located beak, helping the bird achieve its feeding mechanism. The floor of the oropharyngeal cavity is divided into three parts; a pre-lingual part with a pre-lingual fold, a lingual part containing a rudimentary triangular tongue, and a laryngeal part, which contains a small elevated laryngeal mound. Read More

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October 2018
1 Read

Choanal atresia and stenosis: Development and diseases of the nasal cavity.

Authors:
Hiroshi Kurosaka

Wiley Interdiscip Rev Dev Biol 2019 Jan 15;8(1):e336. Epub 2018 Oct 15.

Department of Orthodontics and Dentofacial Orthopedics, Graduate School of Dentistry, Osaka University, Osaka, Japan.

Proper craniofacial development in vertebrates depends on growth and fusion of the facial processes during embryogenesis. Failure of any step in this process could lead to craniofacial anomalies such as facial clefting, which has been well studied with regard to its molecular etiology and cellular pathogenesis. Nasal cavity invagination is also a critical event in proper craniofacial development, and is required for the formation of a functional nasal cavity and airway. Read More

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January 2019
10 Reads

Prognostic Factors and Management of Patients with Choanal Atresia.

J Pediatr 2018 Oct 2. Epub 2018 Oct 2.

Department of Pediatric Otolaryngology Head and Neck Surgery, La Timone Children's Hospital (Aix-Marseille University), Marseille, France.

Objective: To analyze prognostic factors in the management of patients with choanal atresia.

Study Design: This is a review of 114 patients operated on for choanal atresia in a tertiary care center between November 1986 and November 2016, including clinical characteristics, surgical management, and postoperative course with final nasal patency. The data were collected in a database that was updated over time. Read More

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October 2018
12 Reads

Relation between adenoid size and otitis media with effusion.

Eur Ann Otorhinolaryngol Head Neck Dis 2018 Dec 2;135(6):399-402. Epub 2018 Oct 2.

Department of Otorhinolaryngology and Head and Neck Surgery, University Hospital Hradec Kralove, Charles University, Faculty of Medicine in Hradec Kralove, Hradec Kralove, Czech Republic.

Aims: This study compares the efficacy of adenoidectomy on otitis media with effusion (OME) in patients with different size of adenoids and the connection between differently sized adenoids and middle ear effusion.

Material And Methods: Children with a history of at least 3 months' OME underwent adenoidectomy and myringotomy without the insertion of a tympanostomy tube. Treatment assignment was stratified by adenoids' size causing choanal obstruction (grade I-III) and according to Eustachian tube ostium obstruction (grade A-C). Read More

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December 2018
10 Reads

Molecular Detection of Mycoplasma synoviae from Backyard and commercial Turkeys in Some Parts of Iran.

Arch Razi Inst 2018 Jun 1;73(2):79-85. Epub 2018 Mar 1.

Department of Poultry and Obstetrics, Science and Research Branch, Islamic Azad University, Tehran, Iran.

M. synoviae (MS) is an economically important pathogen and the major cause of airsacculitis and infectious synovitis in turkeys. Infection with this pathogen may remain asymptomatic but can render infected birds susceptible to secondary infections. Read More

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June 2018
1 Read

Oropharyngeal Trichomonosis Due to Trichomonas Gypaetinii in a Cinereous Vulture ( Aegypius Monachus) Fledgling in Spain.

J Wildl Dis 2018 Sep 20. Epub 2018 Sep 20.

6 Department of Animal Health, Faculty of Veterinary Sciences, Complutense University of Madrid, Av. Puerta de Hierro, s/n, Madrid 28040, Spain.

A juvenile Cinereous Vulture ( Aegypius monachus) fledgling was found disorientated on the roof of a building in Madrid City, Spain, in October 2016. A veterinary examination revealed multiple plaques distributed throughout the oropharyngeal cavity. Lesions were located under the tongue and at the choanal slit, hard palate, and esophagus opening and ranged from 2 to 7 mm, coalescing in areas up to 2 cm, with a yellowish color of the surface. Read More

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September 2018
2 Reads

Circumaortic double left innominate vein: Two novel echocardiographic diagnostic clues for a tricky diagnosis.

Echocardiography 2018 11 17;35(11):1898-1900. Epub 2018 Sep 17.

Pediatric Interventional Cardiologist, Children's Medical Center (Pediatric Center of Excellence), Affiliated to Tehran University of Medical Sciences, Tehran, Iran.

We report a 7-year-old boy with unilateral choanal atresia who was referred for cardiac consultation before surgery. On echocardiography, the heart was normal except the presence of a double-circle appearance and a V-shaped structure on the suprasternal notch view. Cardiac computed tomography (CT) angiography confirmed the diagnosis of the double left innominate vein (DLIV). Read More

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November 2018
1 Read
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Prevalence of methicillin-resistant Staphylococcus aureus (MRSA) in broilers and workers at 'pluck shops' in Trinidad.

Trop Anim Health Prod 2018 Aug 31. Epub 2018 Aug 31.

School of Veterinary Medicine, Faculty of Medical Sciences, University of the West Indies, St. Augustine, Trinidad and Tobago.

Livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) is a cause of zoonotic infections in many countries. People with occupational contact with food animal production are at risk of colonization. The aim of this study was to determine the prevalence of MRSA and their frequency of resistance to other antimicrobial agents from broilers and workers at the 'pluck shops' in Trinidad. Read More

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August 2018
2 Reads

Congenital Choanal Atresia Repair: An Analysis of Adverse Perioperative Events.

Otolaryngol Head Neck Surg 2018 Nov 28;159(5):920-926. Epub 2018 Aug 28.

2 Department of Otolaryngology-Head and Neck Surgery, School of Medicine, West Virginia University, Morgantown, West Virginia, USA.

Objectives: To identify risk factors and determine the perioperative morbidity of infants undergoing congenital choanal atresia (CCA) repair.

Study Design: Retrospective analysis of the ACS-NSQIP-P database (American College of Surgeons National Surgical Quality Improvement-Pediatric).

Setting: Tertiary medical center. Read More

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November 2018
9 Reads

Pediatric Nasal Obstruction.

Otolaryngol Clin North Am 2018 Oct 19;51(5):971-985. Epub 2018 Jul 19.

Department of Otolaryngology, Upper Airway Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, MLC 2018, Cincinnati, OH 45229, USA; Department of Pulmonary Medicine, Upper Airway Center, Cincinnati Children's Hospital Medical Center, University of Cincinnati, 3333 Burnet Avenue, MLC 2018, Cincinnati, OH 45229, USA. Electronic address:

Nasal obstruction is one of the most common problems seen by pediatric otolaryngologists. Prompt treatment of nasal obstruction can be critical in newborns and infants because of their obligatory nasal breathing. Older children will typically have more inflammatory, infectious, or traumatic causes of nasal obstruction. Read More

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October 2018
17 Reads

Vastus Lateralis Muscle Free Flap for Skull Base Osteoradionecrosis in Nasopharyngeal Carcinoma.

J Neurol Surg B Skull Base 2018 Aug 27;79(4):349-352. Epub 2017 Nov 27.

Department of Otorhinolaryngology, Head and Neck Surgery, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, Hong Kong.

 To describe the first experience with a free vastus lateralis muscle-only flap to be used to cover and protect the exposed skull base and carotid artery from radiotherapy-induced skull base osteoradionecrosis (ORN).  Retrospective review of a case series.  Tertiary academic medical center. Read More

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August 2018
3 Reads

How does nonsyndromic craniosynostosis affect on bone width of nasal cavity in children? - Computed tomography study.

PLoS One 2018 13;13(7):e0200282. Epub 2018 Jul 13.

Department of Radiodiagnostics and Invasive Radiology, School of Medicine in Katowice, Medical University of Silesia, Katowice, Poland.

Craniosynostosis is caused by premature fusion of one or more cranial sutures, restricting skull, brain and face growth. Nonsyndromic craniosynostosis could disturb the proportions of face. Although morphometric diameters of nasal cavity in healthy children are already known, they have not been established yet in children with nonsyndromic craniosynostosis. Read More

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July 2018
6 Reads

The Pathogenesis of Choanal Atresia.

JAMA Otolaryngol Head Neck Surg 2018 Aug;144(8):758-759

Department of Otolaryngology-Head and Neck Surgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

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August 2018
4 Reads

Extranasopharyngeal angiofibroma mimicking choanal polyp in patients with chronic paranasal sinusitis.

Auris Nasus Larynx 2018 Jun 25. Epub 2018 Jun 25.

Department of Otorhinolaryngology-Head and Neck Surgery, Ilsan Paik Hospital, Inje University College of Medicine, Goyang, Republic of Korea. Electronic address:

Extranasopharyngeal angiofibroma (ENA) is an angiofibroma that occurs in the extranasopharynx. It shows pathologic findings, such as juvenile angiofibroma (JNA), which accounts for 0.5% of head and neck mass. Read More

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June 2018
12 Reads

Atypical CHARGE associated with a novel frameshift mutation of CHD7 in a Chinese neonatal patient.

BMC Pediatr 2018 Jun 26;18(1):203. Epub 2018 Jun 26.

Department of Neonatology, Women's Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China.

Background: CHARGE syndrome is an autosomal dominant malformation disorder caused by heterozygous loss of function mutations in the chromatin remodeler CHD7, which has been estimated to occur in 1:10,000 births worldwide. It is a genetic disorder closely resembles other pattern of anomalies. Genetic testing should be pointed out as a useful method for clinical diagnosis. Read More

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June 2018
4 Reads

Infectious bronchitis virus gel vaccination: evaluation of Mass-like (B-48) and 793/B-like (1/96) vaccine kinetics after combined administration at 1 day of age.

Poult Sci 2018 Oct;97(10):3501-3509

Department of Animal Medicine, Production and Health (MAPS), University of Padua, 35020 Legnaro (PD), Italy.

Infectious bronchitis (IB) control has a strong impact on poultry farming, because of the necessary epidemiological knowledge for planning the best strategy, the optimal strain association, the priming and boosting interventions. Broiler farming is even more problematic given the short and intense productive cycle, which requires an early onset of protection against most of the infectious threats, possibly with limited respiratory post-vaccination reactions that would have a direct impact on the bird health and productivity. For this purpose, gel vaccination has been proposed as a new approach for infectious bronchitis virus (IBV) control and vaccine intake, kinetics and compatibility of combined strains administered by gel have been analyzed in this study. Read More

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October 2018
11 Reads

Assessment of posterior choanal obstruction caused by adenoidal hypertrophy: Intra-operative mirror versus rigid nasendoscopic examination.

Int J Pediatr Otorhinolaryngol 2018 Jul 25;110:144-146. Epub 2018 Apr 25.

Department of Ear, Nose and Throat Surgery, Queen's Hospital, Barking, Havering and Redbridge University Hospitals NHS Trust, UK. Electronic address:

Objectives: The aim of the study is to compare the degree of posterior choanal obstruction caused by adenoidal hypertrophy intra-operatively, when assessed by mirror versus rigid nasendoscopic examination, in children undergoing adenoidectomy.

Methods: This is a prospective blinded study including all consecutive paediatric cases undergoing adenoidectomy under care of the senior author during the period from June 2015 to December 2016. All cases were performed under general anaesthesia. Read More

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July 2018
4 Reads

Diagnostic and Therapeutic Management of Nasal Airway Obstruction: Advances in Diagnosis and Treatment.

JAMA Facial Plast Surg 2018 Sep;20(5):409-418

Department of Otolaryngology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston.

Importance: Nasal airway obstruction (NAO) is a common complaint in the otolaryngologist's office and can have a negative influence on quality of life (QOL). Existing diagnostic methods have improved, but little consensus exists on optimal tools. Furthermore, although surgical techniques for nasal obstruction continue to be developed, effective outcome measurement is lacking. Read More

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September 2018
9 Reads

[Analysis of related factors of recurrent otitis media with effusion in children].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2017 Aug;31(15):1168-1173

Department of Otorhinolaryngology, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.

To investigate the influencing factors of recurrent episodes of otitis media with effusion in children.A retrospective summary of the clinical data of 210 cases of children with otitis media with effusion, 75 cases of recurrence after treatment, 135 cases were recovered, the recurrence of the related factors and after symptomatic treatment effect is analyzed.Logistic regression analysis results found that adenoid hypertrophy (Ⅲ°, Ⅳ°), tonsil hypertrophy (Ⅳ°) and sinusitis (including choanal polyp), a positive allergens, upper respiratory tract infection, the stomach esophagus regurgitation, cleft palate, younger age has significant effect on recurrence of otitis media with effusion, have significant difference (< 0. Read More

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Nasal fibroscopy as a routine screening procedure of sinonasal adenocarcinoma of woodworkers: French longitudinal case study.

Head Neck 2018 Oct 13;40(10):2193-2198. Epub 2018 May 13.

Occupational Disease Department, CHU de Toulouse, Toulouse, France.

Background: The purpose of this study was to assess the relevancy of flexible nasoendoscopy as a routine screening procedure of sinonasal adenocarcinoma among people occupationally exposed to wood dust.

Methods: This study included woodworkers, occupationally exposed to wood dust. Evaluations were scheduled at the time of inclusion (T0) and after a 2-year period (T1). Read More

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October 2018
2 Reads

Iatrogenic traumatic optic neuropathy: report of an injury occurring during a choanal atresia correction surgery treatment.

J Biol Regul Homeost Agents 2018 Mar-Apr;32(2 Suppl. 2):87-90

Section of Oral and Maxillofacial Surgery, Department of Surgical Sciences, Dentistry, Gynecology and Pediatrics, University of Verona, Italy.

We report the case of a 36-year-old adult male patient who came to our attention for the evaluation of a possible iatrogenic injury suffered during the surgical correction of congenital choanal atresia. This case report retraces the patient's medical history and the events lapsed in the peri-operative time analyzing if any malpractice has occurred in causing the amaurosis. Read More

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May 2018
2 Reads

Clival Malformations in CHARGE Syndrome.

AJNR Am J Neuroradiol 2018 Jun 5;39(6):1153-1156. Epub 2018 Apr 5.

From the Department of Diagnostic Imaging and Radiology (E.S.M., M.T.W.), Children's National Medical Center, Washington, DC.

Background And Purpose: CHARGE syndrome is a multisystemic congenital disorder, most commonly including coloboma, heart malformations, choanal atresia, developmental delay, and genital and ear anomalies. The diagnostic criteria for CHARGE syndrome have been refined with time. However, limited reports describe skull base and craniocervical junction abnormalities. Read More

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June 2018
2 Reads

Detection of Mycoplasma gallisepticum in House Finches ( Haemorhous mexicanus) from Arizona.

Avian Dis 2018 Mar;62(1):14-17

A Department of Biological Sciences, Auburn University, Auburn, AL 36849.

In 1994, an endemic poultry pathogen, Mycoplasma gallisepticum (MG), was identified as the causative agent of a novel disease in house finches ( Haemorhous mexicanus). After an initial outbreak in Maryland, MG spread rapidly throughout eastern North American populations of house finches. Subsequently, MG spread slowly through the northern interior of North America and then into the Pacific Northwest, finally reaching California in 2006. Read More

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March 2018
7 Reads

Novel Chlamydia species isolated from snakes are temperature-sensitive and exhibit decreased susceptibility to azithromycin.

Sci Rep 2018 Apr 4;8(1):5660. Epub 2018 Apr 4.

Institute for Veterinary Pathology, Vetsuisse Faculty, University of Zurich, Winterthurerstrasse 268, CH-8057, Zurich, Switzerland.

Chlamydia species have recently been recognized as emerging pathogens in snakes. However, isolation of novel snake chlamydiae is critical and their growth characteristics are largely unknown. In this study, two novel chlamydial species are described: Chlamydia serpentis and Chlamydia poikilothermis, isolated after attempts on 23 cloacal and choanal swabs from 18 PCR-positive captive snakes originating from different Swiss snake collections. Read More

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April 2018
9 Reads

Combined Nasoseptal and Inferior Turbinate Flap for Reconstruction of Large Skull Base Defect After Expanded Endonasal Approach: Operative Technique.

Oper Neurosurg (Hagerstown) 2019 Jan;16(1):45-52

Department of Neurosurgery, Hôpital Lariboisière, AP-HP, Paris, France.

Backround: Increasing indications for endoscopic endonasal approaches have led neurosurgeons to develop new reconstruction techniques for larger skull base defects. Vascularized grafts have been a great adjunction to reduce the rate of cerebrospinal fluid leak and can also be used to cover exposed critical structures such as the internal carotid artery. The nasoseptal flap and the inferior or middle turbinate flap are thus widely used in endoscopic skull base surgery, but may be insufficient for very large defects. Read More

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January 2019
5 Reads

Congenital sodium diarrhea and chorioretinal coloboma with optic disc coloboma in a patient with biallelic SPINT2 mutations, including p.(Tyr163Cys).

Am J Med Genet A 2018 04;176(4):997-1000

Division of Genetics, Department of Pediatrics, University of California, San Francisco, San Francisco, California.

Congenital sodium diarrhea is a rare and life-threatening disorder characterized by a severe, secretory diarrhea containing high concentrations of sodium, leading to hyponatremia and metabolic acidosis. It may occur in isolation or in association with systemic features such as facial dysmorphism, choanal atresia, imperforate anus, and corneal erosions. Mutations in the serine protease inhibitor, Kunitz-Type 2 (SPINT2) gene have been associated with congenital sodium diarrhea and additional syndromic features. Read More

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April 2018
4 Reads

[Diagnostics and management of choanal atresia].

HNO 2018 Apr;66(4):329-338

HNO-Klinik, Klinikum Stuttgart, Stuttgart, Deutschland.

Choanal atresia is a rare malformation that represents a special challenge. While bilateral choanal atresia usually needs to be surgically treated within a few days of birth, the intervention for one-sided choanal atresia can be postponed for years. Treatment planning requires adequate imaging (CT or MRI), which also serves to exclude other skull base malformities. Read More

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April 2018
6 Reads

Isolated choanal and gut atresias: pathogenetic role of serine protease inhibitor type 2 (SPINT2) gene mutations unlikely.

Eur J Med Res 2018 Mar 2;23(1):13. Epub 2018 Mar 2.

Department of Pediatrics I, Medical University of Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria.

Background: Choanal (CA) and gastrointestinal atresias (GA) are an important feature of syndromic congenital sodium diarrhea (sCSD), a disorder recently associated with mutations in the gene for serine protease inhibitor type 2 (SPINT2). It is, however, not known whether isolated non-syndromic CA and GA themselves might result from SPINT2 mutations.

Methods: We performed a prospective cohort study to investigate 19 CA and/or GA patients without diarrhea ("non-sCSD") for potential sCSD characteristic clinical features and SPINT2 mutations. Read More

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March 2018
6 Reads

Dealing a Neonate with CHARGE Syndrome:Anaesthesia perspective of perioperative care.

Pak J Med Sci 2017 Nov-Dec;33(6):1534-1537

Dr. Amjad Nadeem, FCPS. Department of Anaesthesia, Aga Khan University Hospital Karachi, Pakistan.

CHARGE syndrome is a condition that can disturb numerous areas of human body. As an abbreviation CHARGE stands for: coloboma, heart defects, atresia choanae, and retardation of growth, genital, and ear abnormalities. The configuration of malformations differs among individuals with this disorder, and the various health issues can be life-threatening during infancy and childhood. Read More

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March 2018
3 Reads

Early Transient Prenatal Ultrasound Features of Choanal Atresia.

J Ultrasound Med 2018 Oct 26;37(10):2439-2444. Epub 2018 Feb 26.

Helen Schneider Hospital for Women, Rabin Medical Center, Petach-Tikva, Israel.

We present a case series of early second-trimester prenatal ultrasound (US) features in 4 fetuses with a confirmed diagnosis of choanal atresia. The clinical characteristics and outcomes evaluated included prenatal US findings, genetic analyses, postmortem autopsies (2 cases), and computed tomographic findings. A transient large nasal cavity was detected by US in all 4 fetuses. Read More

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October 2018
3 Reads

Chitosan-adjuvanted Mycoplasma gallisepticum bacterin via intraocular administration enhances Mycoplasma gallisepticum protection in commercial layers.

Poult Sci 2018 Jun;97(6):1934-1940

Avian Health Research Unit, Department of Veterinary Medicine, Faculty of Veterinary Science, Chulalongkorn University, Patumwan, Bangkok 10330, Thailand.

Mycoplasma gallisepticum (MG) causes respiratory signs and economic losses in the poultry industry. MG vaccination is one of the effective prevention and control measures that have been used around the world. Our previous study demonstrated that chitosan-adjuvanted MG bacterin could effectively reduce pathological lesions induced by MG and that chitosan could be used as an adjuvant in MG bacterin. Read More

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June 2018
1 Read

Choanal Atresia: Birth Without Breath.

Indian J Otolaryngol Head Neck Surg 2018 Mar 16;70(1):53-58. Epub 2017 Oct 16.

2Department of ENT, Government Medical College, Bhavnagar, Gujarat India.

Bilateral Choanal atresia is a medical emergency. Corrective surgery is the mainstay of the treatment. Hegar's dilator was used in all cases to break the bony/membranous atretic plate. Read More

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March 2018
7 Reads

Endoscopic Surgery for Delayed Sinonasal Complications of Radiation Therapy for Nasopharyngeal Carcinoma: A Subjective Outcome.

Int J Radiat Oncol Biol Phys 2018 Apr 9;100(5):1222-1227. Epub 2018 Jan 9.

Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; Department of Otorhinolaryngology Head and Neck Surgery, Chaim Sheba Medical Center, Tel HaShomer, Israel. Electronic address:

Purpose: Delayed sinonasal complications of radiation therapy include choanal stenosis, osteoradionecrosis, chronic sinusitis, and intranasal synechiae. Only sporadic cases on their surgical treatment have been reported, with equivocal results.

Methods And Materials: We performed a prospective case series of all patients who had been surgically treated for delayed sinonasal complications of radiation therapy in our institution during the past 10 years. Read More

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April 2018
1 Read

Cleft Lip and Palate in CHARGE Syndrome: Phenotypic Features That Influence Management.

Cleft Palate Craniofac J 2018 Mar 14;55(3):342-347. Epub 2017 Dec 14.

1 Department of Plastic and Oral Surgery, Boston Children's Hospital, Boston, MA, USA.

Objective: Infants with syndromic cleft lip and/or cleft palate (CL/P) often require more complex care than their nonsyndromic counterparts. Our purpose was to (1) determine the prevalence of CL/P in patients with CHARGE syndrome and (2) highlight factors that affect management in this subset of children.

Design: This is a retrospective review from 1998 to 2016. Read More

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March 2018
3 Reads

[Endonasal endoscopic surgery of choanal atresia - long term results].

Laryngorhinootologie 2018 Feb 8. Epub 2018 Feb 8.

Universitätsklinikum Essen Klinik für Hals-Nasen-Ohren-Heilkunde, Kopf- und Hals-Chirurgie.

Introduction:  Choanal atresia is a rare abnormality. As neonates depend on transnasal respiration, bilateral choanal atresia causes an acute emergency. Transnasal endoscopic resection of congenital choanal atresia is a well-established therapy. Read More

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February 2018
6 Reads

Radiological comparison of inferior turbinate hypertrophy between allergic and non-allergic rhinitis: does allergy really augment turbinate hypertrophy?

Eur Arch Otorhinolaryngol 2018 Apr 7;275(4):923-929. Epub 2018 Feb 7.

Department of Otorhinolaryngology, Yonsei University College of Medicine, 50 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

Background: Inferior turbinate hypertrophy could be a result of allergic rhinitis (AR) that leads to nasal congestion and nasal airway obstruction, which is the most bothersome complaint in patients with AR. However, evidence regarding whether patients with AR have a more hypertrophied inferior turbinate than do patients with non-AR is lacking.

Objective: We aimed to evaluate the degree of inferior turbinate hypertrophy according to the presence of AR using radiological measurements of the inferior turbinate. Read More

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April 2018
2 Reads

Maxillo Ostio Choanal Polyp.

Balkan Med J 2018 01;35(1):116-117

Department of Otorhinolaryngology, Karabük University School of Medicine, Karabük, Turkey.

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January 2018
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CHLAMYDIA PSITTACI IN FERAL ROSY-FACED LOVEBIRDS ( AGAPORNIS ROSEICOLLIS) AND OTHER BACKYARD BIRDS IN MARICOPA COUNTY, ARIZONA, USA.

J Wildl Dis 2018 04 25;54(2):248-260. Epub 2018 Jan 25.

6   University of Georgia, College of Veterinary Medicine, Infectious Diseases Laboratory, 110 Riverbend Road, Athens, Georgia 30602, USA.

In 2013, a mortality event of nonnative, feral Rosy-faced Lovebirds ( Agapornis roseicollis) in residential backyards in Maricopa County, Arizona, US was attributed to infection with Chlamydia psittaci. In June 2014, additional mortality occurred in the same region. Accordingly, in August 2014 we sampled live lovebirds and sympatric bird species visiting backyard bird feeders to determine the prevalence of DNA and the seroprevalence of antibodies to C. Read More

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April 2018
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