28,596 results match your criteria Chlamydia


Does Male Circumcision Reduce Women's Risk of Sexually Transmitted Infections, Cervical Cancer, and Associated Conditions?

Front Public Health 2019 31;7. Epub 2019 Jan 31.

Department of Urology, University of Washington School of Medicine, Seattle, WA, United States.

Male circumcision (MC) is proven to substantially reduce men's risk of a number of sexually transmitted infections (STIs). We conducted a detailed systematic review of the scientific literature to determine the relationship between MC and risk of STIs and associated conditions in women. Database searches by "circumcision women" and "circumcision female" identified 68 relevant articles for inclusion. Read More

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http://dx.doi.org/10.3389/fpubh.2019.00004DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365441PMC
January 2019
1 Read

Seventy Years of Vaccine Research - Limitations of the Past and Directions for the Future.

Front Microbiol 2019 31;10:70. Epub 2019 Jan 31.

Genecology Research Centre, The University of the Sunshine Coast, Maroochydore, QLD, Australia.

is a major bacterial pathogen that infects humans, as well as a wide range of animals, including marsupials, birds, cats, pigs, cattle, and sheep. Antibiotics are the only treatment currently available, however, with high rates of re-infection, there is mounting pressure to develop vaccines. In this review, we analyzed how vaccine trials have developed over the past 70 years and identified where future trials need to be focused. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2019.00070
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http://dx.doi.org/10.3389/fmicb.2019.00070DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6365973PMC
January 2019
2 Reads

Randomized, open-label, multicenter study of azithromycin compared with doxycycline for treating anorectal Chlamydia trachomatis infection concomitant to a vaginal infection (CHLAZIDOXY study).

Medicine (Baltimore) 2019 Feb;98(7):e14572

University Bordeaux.

Background: Chlamydia trachomatis can lead to a persistent infection in the lower gastrointestinal tract, suggesting a potential role of autoinoculation of cervical chlamydial infection from the rectal site, contributing to repeat infections. Moreover, around 75% of women with urogenital C. trachomatis have concurrent anorectal infection. Read More

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http://dx.doi.org/10.1097/MD.0000000000014572DOI Listing
February 2019
2 Reads

An evaluation of sexually transmitted infection and odds of preterm or early term birth using propensity score matching.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

California Preterm Birth Initiative, University of California San Francisco, San Francisco, California, USA.

Background: Few studies have examined the relationship between sexually transmitted infections (STIs) and preterm birth (<37 weeks gestation) by subtype (<32 weeks, 32 - 36 weeks, spontaneous, provider-initiated). Here, we evaluate the odds of preterm (by subtype) and early term (37 and 38 weeks gestation) birth in women with an STI compared to a propensity score matched reference population.

Methods: The sample was selected from California births in 2007-2012. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000985DOI Listing
February 2019
1 Read

The prevalence of Mycoplasma genitalium and association with HIV infection in symptomatic patients, Johannesburg, South Africa, 2007-2014.

Sex Transm Dis 2019 Feb 11. Epub 2019 Feb 11.

Centre for HIV & STIs, National Institute for Communicable Diseases, National Health Laboratory Service, Johannesburg, South Africa.

Background: Mycoplasma genitalium is associated with genital discharge syndrome, but limited prevalence data is available in South Africa. The prevalence rates of M. genitalium infection and HIV co-infection were determined in urogenital specimens collected from male and female patients presenting with genital discharge syndrome to a primary health care centre in Johannesburg, South Africa from 2007 through 2014. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000984DOI Listing
February 2019
1 Read

Fitz-Hugh-Curtis Syndrome: A Diagnosis to Consider in a Woman with Right Upper Quadrant Abdominal Pain without Gallstones.

Eur J Case Rep Intern Med 2018 22;5(2):000743. Epub 2018 Feb 22.

Internal Medicine Department, Ospedale La Carità, Locarno, Switzerland.

A young woman presented with right upper quadrant abdominal pain exacerbated by movement and breathing. Extensive evaluation revealed no gallstones or any other specific cause. Urine polymerase chain reaction results for were positive, so the clinical diagnosis of Fitz-Hugh-Curtis syndrome was confirmed. Read More

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http://dx.doi.org/10.12890/2017_000743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346932PMC
February 2018

Chlamydia trachomatis in women with pelvic inflammatory disease (PID): report from a tertiary center in eastern Nepal.

Trop Doct 2019 Feb 12:49475519826195. Epub 2019 Feb 12.

6 Additional Professor, Department of Microbiology, BP Koirala Institute of Health Sciences, Dharan, Nepal.

Chlamydia trachomatis is an important agent of pelvic inflammatory disease (PID) globally. Laboratory diagnosis, which is vital for early and appropriate treatment, remains a challenge in resource-limited settings. Our study was undertaken to detect C. Read More

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http://dx.doi.org/10.1177/0049475519826195DOI Listing
February 2019

Chlamydia pneumoniae enhances Interleukin 8 (IL-8) production with reduced azithromycin sensitivity under hypoxia.

APMIS 2019 Mar;127(3):131-138

Department of Medical Laboratory Science, Faculty of Health Sciences, Hokkaido University, Sapporo, Japan.

Obligate intracellular bacterium Chlamydia pneumoniae causes respiratory tract infections such as community-acquired pneumonia. During infection, C. pneumoniae induces inflammatory responses in host cells and the oxygen concentration at the infection sites subsequently decreases. Read More

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http://dx.doi.org/10.1111/apm.12924DOI Listing
March 2019
1 Read

Targeted advertisement of chlamydia screening on social media: A mixed-methods analysis.

Digit Health 2019 Jan-Dec;5:2055207619827193. Epub 2019 Feb 1.

School of Psychology, The University of Southampton, Southampton, UK.

Objective: Chlamydia is one of the most common sexually transmitted infections in teenagers and young adults. This study used a mixed-methods analysis to investigate targeted promotion of chlamydia home-testing on social media.

Methods: Our first study, in which face-to-face interviews with young women were conducted, sought to explore their attitudes and preferences towards social media-based health promotion. Read More

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http://dx.doi.org/10.1177/2055207619827193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360644PMC
February 2019
1 Read

Dermatologic care for lesbian, gay, bisexual, and transgender persons: Epidemiology, screening, and disease prevention.

J Am Acad Dermatol 2019 Mar;80(3):591-602

Department of Dermatology, Kaiser Permanente, San Francisco, California.

Lesbian, gay, bisexual, and transgender (LGBT) persons face important health issues relevant to dermatologists. Men who have sex with men (MSM) are at higher risk of certain infectious diseases, including HIV, syphilis and other sexually transmitted diseases (STDs), methicillin-resistant Staphylococcus aureus infections, and invasive meningococcal disease, and might be at higher risk of non-infectious conditions, including skin cancer. Recommendations for preventive health care, including screening for HIV and other STDs, sexual health-related vaccinations, and HIV pre-exposure prophylaxis, differ for MSM compared with non-MSM. Read More

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http://dx.doi.org/10.1016/j.jaad.2018.02.045DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6375301PMC
March 2019
1 Read

Presumptive and Follow-up Treatment for Gonorrhea and Chlamydia Among Patients Attending Public Health Department Clinics in Virginia, 2016.

Sex Transm Dis 2019 Mar;46(3):199-205

Background: Presumptive antibiotic treatment is common for suspected chlamydia (CT) and gonorrhea (GC) infections before laboratory confirmation to prevent complications, reduce loss-to-follow-up, and interrupt transmission. We assessed this practice in sexually transmitted disease (STD) and family planning clinics.

Methods: We performed a retrospective analysis of data from clinics in Virginia in 2016 using administrative data merged with electronic laboratory reporting data. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000922DOI Listing

Flap endonuclease-initiated enzymatic repairing amplification for ultrasensitive detection of target nucleic acids.

Nanoscale 2019 Feb 11. Epub 2019 Feb 11.

Department of Chemical and Biomolecular Engineering (BK 21+ program), KAIST, Daehak-ro 291, Yuseong-gu, Daejeon 305-701, Republic of Korea.

A new isothermal nucleic acid amplification method termed FERA (Flap endonuclease-initiated Enzymatic Repairing Amplification) is developed for the ultrasensitive detection of target nucleic acids. In the FERA method, flap endonuclease (FEN) catalyzes the hydrolytic cleavage at the junction of single- and double-stranded DNAs which is formed only in the presence of target nucleic acids, and releases short oligonucleotides to promote the cyclic enzymatic repairing amplification (ERA) combined with FEN-based amplification. As a result, a large amount of single- and double-stranded DNAs are generated under the isothermal conditions, leading to the high fluorescence intensity from the SYBR I green dye. Read More

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http://dx.doi.org/10.1039/c8nr06699jDOI Listing
February 2019

Acceptability and feasibility of sexually transmissible infection screening among pregnant women in Hanoi, Vietnam.

Sex Health 2019 Feb 11. Epub 2019 Feb 11.

Vietnam currently has no antenatal screening program for curable sexually transmissible infections (STIs). The aim of this study was to determine the prevalence of curable STIs, correlates of infections and assess the acceptability and feasibility of antenatal STI screening in Hanoi, Vietnam. A study involving 800 pregnant women visiting Ha Dong Hospital in Hanoi, Vietnam from June 2016 to July 2017, was conducted. Read More

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http://dx.doi.org/10.1071/SH18041DOI Listing
February 2019

Chinese Herbal Formula Feilin Vaginal Gel Prevents the Cervicitis in Mouse Model.

Evid Based Complement Alternat Med 2019 10;2019:4168126. Epub 2019 Jan 10.

Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing 100700, China.

Cervicitis is a common sexually transmitted disease. In recent years, the abuse of antibiotic in the treatment of cervicitis results in the emergence of antibiotic-resistant bacteria; alternative strategies are needed to be developed. In this research, we investigated the effects of Feilin Vaginal Gel (FVG), a Chinese herbal formula, on the treatment of cervicitis. Read More

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http://dx.doi.org/10.1155/2019/4168126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348856PMC
January 2019
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HPV-Chlamydial Coinfection, Prevalence, and Association with Cervical Intraepithelial Lesions: A Pilot Study at Mbarara Regional Referral Hospital.

J Cancer Epidemiol 2019 10;2019:9092565. Epub 2019 Jan 10.

PhD, (MUK), Makerere University, College of Health Science, P.O. Box 7072, Kampala, Uganda.

Background: Human Pappilloma Virus (HPV) is the necessary cause of cervical cancer. A number of risk factors are believed to influence the role of HPV in the development of cervical cancer. This is so because majority of HPV infections are cleared and only a few are able to result into cancer. Read More

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http://dx.doi.org/10.1155/2019/9092565DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348791PMC
January 2019

Standardisation is necessary in urogenital and extragenital bacterial load determination by quantitative PCR: a review of literature and retrospective study.

Sex Transm Infect 2019 Feb 7. Epub 2019 Feb 7.

Department of Medical Microbiology, Maastricht University Medical Center, School of Public Health and Primary Care, Maastricht, The Netherlands.

Objectives: Pathogen load has been linked to disease severity in patients infected with HIV, resulting in international standards to adequately and reproducibly quantify load. (CT) load has been inconsistently linked to disease severity since extensive differences exist in quantification methods (14 methods in 28 articles). Differences include normalisation for human cell load due to CT's intracellular nature, despite the inability to distinguish inflammatory cells from epithelial cells with molecular techniques. Read More

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http://dx.doi.org/10.1136/sextrans-2018-053522DOI Listing
February 2019
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Identifying young people exposed to or at risk of sexual ill health: pilot implementation of an evidence-informed toolkit (SEXIT) at Swedish youth clinics.

Eur J Contracept Reprod Health Care 2019 Feb 7:1-9. Epub 2019 Feb 7.

f Närhälsan Research and Development Primary Health Care , Gothenburg , Sweden.

Objectives: We aimed to develop and pilot-implement an evidence-informed toolkit (SEXual health Identification Tool; SEXIT) for identifying young people exposed to or at risk of sexual ill health, at Swedish youth clinics, and to investigate SEXIT's potential to identify young people in need of special care and monitoring.

Methods: The SEXIT toolkit was developed, validated and pilot-implemented at three Swedish youth clinics. Pre-implementation staff readiness was assessed and youth clinic visitors' responses to SEXIT were analysed. Read More

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http://dx.doi.org/10.1080/13625187.2018.1564815DOI Listing
February 2019

A rare case of Fitz-Hugh-Curtis syndrome caused by in an HIV-positive male patient.

SAGE Open Med Case Rep 2019 16;7:2050313X18823592. Epub 2019 Jan 16.

University Hospital for Infectious Diseases 'Dr. Fran Mihaljević', Zagreb, Croatia.

Fitz-Hugh-Curtis syndrome, a rare complication of pelvic inflammatory disease, is an inflammation of the liver capsule (thus called perihepatitis) and the surrounding peritoneum. It occurs extremely rarely in men and is typically characterized by a sudden onset of severe pain in the right upper abdominal quadrant. Ultrasound examination of the liver does not reveal any morphologic changes, and liver function tests are usually normal. Read More

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http://dx.doi.org/10.1177/2050313X18823592DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350016PMC
January 2019
2 Reads

[Document: Chlamydia trachomatis: fundamentals of the importance of screening in the public health system].

Rev Chilena Infectol 2018 ;35(5):498-500

Comité de Advocacy de Chlamydia, Sociedad Chilena de Obstetricia y Ginecología Infantil y de la Adolescencia, Chile.

The sexually transmitted infection caused by Chlamydia trachomatis has a high prevalence in Chile and other latitudes and is associated with serious risks to the reproductive health of those who become infected. Screening with self- collected samples and detection by amplification of nucleic acids is the most effective form of sanitary control. Until now, in Chile, the diagnosis and epidemiological management of C. Read More

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http://dx.doi.org/10.4067/s0716-10182018000500498DOI Listing
January 2018

Bacterial sexually transmitted infections in France: recent trends and patients' characteristics in 2016.

Euro Surveill 2019 Jan;24(5)

Santé publique France (the French national public health agency), Saint-Maurice, France.

Diagnoses of bacterial sexually transmitted infections (STI) have been increasing in France since their resurgence in the late 1990s. This article presents recent epidemiological trends until 2016 and the patients' characteristics. STI surveillance relies on sentinel networks: a clinician-based network RésIST (clinical, biological and behavioural data for early syphilis and gonorrhoea), the lymphogranuloma venereum (LGV) network (clinical, biological and behavioural data for rectal LGV, and the laboratory networks Rénachla and Rénago (demographic and biological data for chlamydial infections and gonorrhoea, respectively). Read More

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http://dx.doi.org/10.2807/1560-7917.ES.2019.24.5.1800038DOI Listing
January 2019
3 Reads

A case report of proctitis associated with Mycoplasma genitalium in a man who has sex with men.

Int J STD AIDS 2019 Feb 5:956462419825896. Epub 2019 Feb 5.

3 STI Unit Vall d'Hebron - Drassanes, Infectious Diseases Department, Hospital Vall d'Hebron, Barcelona, Spain.

Mycoplasma genitalium is an infection of increasing concern due to its potential to cause sequelae in the reproductive tract and the development of antimicrobial resistance. Its role as a cause of proctitis in people with high-risk sexual behaviour has not been properly defined yet but it seems to be less symptomatic than proctitis caused by Chlamydia trachomatis or Neisseria gonorrhoeae. We present a case of a man who has sex with men with proctitis associated with M. Read More

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http://dx.doi.org/10.1177/0956462419825896DOI Listing
February 2019
1 Read

[Ocular lesions in HIV-infected patients of the ophthalmic hospitals].

Vestn Oftalmol 2018 ;134(6):25-32

Perm State Medical University named after E.A. Wagner, 26 Petropavlovskaya St., Perm, Russian Federation, 614000; Institute of Immunology and Physiology, Ural Branch of the Russian Academy of Sciences, 91 Pervomaiskaya St., Yekaterinburg, Russian Federation, 620041.

Purpose: To analyze ophthalmic pathologies in HIV-infected patients of the ophthalmic hospitals of Perm city.

Material And Methods: Medical records of 75 HIV patients registered in Perm Regional Centre for Prevention and Control of AIDS and Infectious Diseases who had received treatment in ophthalmic in-patient clinics of Perm in 2005-2015 years were analyzed retrospectively. Patient examination included traditional ophthalmological methods, as well as immunological (determination of CD4 cells and viral load), serological (detection of antibodies to herpes simplex virus, cytomegalovirus, chlamydia, toxoplasma), general clinical methods, and consultations by allied specialists. Read More

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http://dx.doi.org/10.17116/oftalma201813406125DOI Listing
January 2018
3 Reads

Concurrent and time-lagged effects of social disorganization on chlamydia rate trajectories among United States counties and the District of Columbia, 2010-2015.

Sex Transm Dis 2019 Jan 30. Epub 2019 Jan 30.

Department of Epidemiology, Robert Stempel College of Public Health and Social Work, Florida International University, Miami, FL.

Objective: To examine the longitudinal relationship between social disorganization (SD) and genital Chlamydia trachomatis infection.

Methods: US county-level data for 2010-2015 were used. Reliability and principal component analysis revealed two SD factors: socioeconomic deprivation and demographic instability. Read More

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http://dx.doi.org/10.1097/OLQ.0000000000000982DOI Listing
January 2019
1 Read
2.842 Impact Factor

Occurrence of human papillomavirus (HPV) type replacement by sexual risk-taking behaviour group: Post-hoc analysis of a community randomized clinical trial up to nine years after vaccination (IV).

Int J Cancer 2019 Feb 5. Epub 2019 Feb 5.

Faculty of Social Sciences, Tampere University, Finland.

Oncogenic non-vaccine human papillomavirus (HPV) types may conceivably fill the vacated ecological niche of the vaccine types. The likelihood of this may differ by the risk of acquiring HPV infections. We examined occurrence of HPV types among vaccinated and unvaccinated subgroups of 1992-1994 birth cohorts with differing acquisition risks up to 9 years post-implementation of HPV vaccination in 33 Finnish communities randomized to: Arm A (gender-neutral HPV16/18 vaccination), Arm B (girls-only HPV16/18 vaccination and hepatitis B-virus (HBV) vaccination of boys), and Arm C (gender-neutral HBV vaccination). Read More

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http://dx.doi.org/10.1002/ijc.32189DOI Listing
February 2019
1 Read

Autophagy induction and PDGFR-β knockdown by siRNA-encapsulated nanoparticles reduce chlamydia trachomatis infection.

Sci Rep 2019 Feb 4;9(1):1306. Epub 2019 Feb 4.

University of Manitoba, College of Pharmacy, 750 McDermot Ave, Winnipeg, Manitoba, R3E 0T5, Canada.

C. trachomatis is the most common sexually transmitted bacterial infection in the world. Although the infection can be easily controlled by the use of antibiotics, several reports of clinical isolates that are resistant to antibiotics have prompted us to search for alternative strategies to manage this disease. Read More

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http://dx.doi.org/10.1038/s41598-018-36601-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6361950PMC
February 2019
1 Read

Lymphogranuloma venereum presenting as penile ulcer in two HIV-negative gay men.

Int J STD AIDS 2019 Feb 4:956462418821579. Epub 2019 Feb 4.

3 RPA Sexual Health, Sydney Local Health District, Camperdown, Australia.

An epidemic of lymphogranuloma venereum among men who have sex with men (MSM) has persisted in Australia for over a decade and virtually all diagnoses are made from rectal samples. We discuss two cases of human immunodeficiency virus-negative MSM who presented with a penile ulcer. The diagnosis can be made by ensuring a swab of any such ulcer is tested for Chlamydia trachomatis. Read More

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http://dx.doi.org/10.1177/0956462418821579DOI Listing
February 2019

The use of multiplex PCR for the detection of atypical pathogens in Egyptian children with CAP: a high rate of in early infancy.

J Egypt Public Health Assoc 2019 18;94(1). Epub 2019 Jan 18.

2Department of Clinical Pathology, Faculty of Medicine, Cairo University, 2 Atteia Abd El Hadi St., El Maadi, Cairo, 11562 Egypt.

Background: Atypical pathogen infections played an important role in community-acquired pneumonia (CAP) in children. Pathogen-specific clinical symptoms are often lacking, and it is difficult to detect atypical pathogens by culture methods. The use of multiplex polymerase chain reaction (PCR) methods enables testing for many pathogens simultaneously in a single analysis. Read More

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http://dx.doi.org/10.1186/s42506-018-0003-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6338716PMC
January 2019
6 Reads

Bacteriologic Profile and Susceptibility Pattern of Mechanically - Ventilated Pediatric Patients with Pneumonia.

J Glob Antimicrob Resist 2019 Jan 30. Epub 2019 Jan 30.

Department of Pediatrics, Alexandria University, Faculty of Medicine, El-Shatby Hospital, Alexandria, Egypt. Electronic address:

Purpose: Therapy of severe pneumonia is very challenging in view of the current widespread bacterial resistance to many antibiotics especially extended spectrum ß-lactams, carbapenems, and anti-pseudomonal drugs. The current study aimed at assessing antimicrobial sensitivity pattern and optimization of the antibiotic stewardship program applied in a university affiliated pediatric intensive care unit (PICU).

Subjects And Methods: This prospective cohort study included all patients aged 1 month to 12 years, admitted to the PICU with severe pneumonia episodes indicated for mechanical ventilation, and were followed up and investigated. Read More

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http://dx.doi.org/10.1016/j.jgar.2019.01.028DOI Listing
January 2019
1 Read

Optimization of a rapid test for antibodies to the Chlamydia trachomatis antigen Pgp3.

Diagn Microbiol Infect Dis 2018 Nov 10. Epub 2018 Nov 10.

Division of Parasitic Diseases and Malaria, Centers for Disease Control and Prevention, Atlanta, GA, USA. Electronic address:

Serological surveillance for trachoma could allow monitoring of transmission levels in areas that have achieved elimination targets. Platforms that allow testing in basic laboratories or testing of easy-to-manage samples such as dried blood spots would contribute to the feasibility of serologic testing. Blood from 506 1-12-year-olds in 2 villages in Kongwa district, Tanzania, was tested for antibodies against the antigen Pgp3. Read More

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http://dx.doi.org/10.1016/j.diagmicrobio.2018.11.001DOI Listing
November 2018

Screening for Sexually Transmitted Diseases.

Prim Care 2019 Mar 24;46(1):157-173. Epub 2018 Dec 24.

Residency in General Preventive Medicine and Public Health, Florida Department of Health, Palm Beach County, 800 Clematis, West Palm Beach, FL 33401, USA.

This article discusses sexually transmitted infections (STI) screening and focuses on reportable STIs. This includes gonorrhea, chlamydia, syphilis, and human immunodeficiency virus. Hepatitis B and C, trichomonas, and herpes are covered as well. Read More

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http://dx.doi.org/10.1016/j.pop.2018.10.013DOI Listing
March 2019
3 Reads

Endogenous IL-17A mediated neutrophil infiltration by promoting chemokines expression during chlamydial lung infection.

Microb Pathog 2019 Jan 28;129:106-111. Epub 2019 Jan 28.

Department of Immunology, School of Basic Medical Sciences, Tianjin Medical University, Tianjin Key Laboratory of Cellular and Molecular Immunology, Key Laboratory of Educational Ministry of China, Tianjin, PR China. Electronic address:

Chlamydia is an obligate intracellular bacteria, which can infect cervix, urethra, conjunctiva, joints, lungs and so on. Neutrophils are important in host protection against microbial invasion during the early phase of infection. Here, to investigate the mechanism of IL-17A in recruiting neutrophils during Chlamydia muridarum (Cm) lung infection, we introduced IL-17A antibodies and IL-17 mice to confirm the effect of IL-17A on influencing neutrophil attractants expressions. Read More

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http://dx.doi.org/10.1016/j.micpath.2019.01.039DOI Listing
January 2019

Round pneumonia due to in a child.

Radiol Case Rep 2019 Apr 18;14(4):436-438. Epub 2019 Jan 18.

Department of Pediatrics, National Hospital Organization Saitama National Hospital, Saitama, Japan.

Round pneumonia is a disease commonly recognized in the pediatric age group, especially under the age of 8 years. is the most common agent causing this characteristic type of pneumonia. We herein report a case of a 6-year-old boy with only mild cough and low-grade fever who was then diagnosed with round pneumonia due to . Read More

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http://dx.doi.org/10.1016/j.radcr.2019.01.010DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348194PMC
April 2019
1 Read

A Synthetic, Small, Sulfated Agent Is a Promising Inhibitor of . Infection .

Front Microbiol 2018 16;9:3269. Epub 2019 Jan 16.

Department of Microbiology and Immunology, College of Graduate Studies, Midwestern University, Downers Grove, IL, United States.

is the most frequently reported sexually transmitted bacteria causing 2.9 million infections annually in the United States. Diagnosis, treatment, and sequelae of chlamydial disease cost billions of dollars each year in the United States alone. Read More

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https://www.frontiersin.org/article/10.3389/fmicb.2018.03269
Publisher Site
http://dx.doi.org/10.3389/fmicb.2018.03269DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6343517PMC
January 2019
3 Reads

Young people's preferences for the use of emerging technologies for asymptomatic regular chlamydia testing and management: a discrete choice experiment in England.

BMJ Open 2019 Jan 29;9(1):e023663. Epub 2019 Jan 29.

Enterprise and Innovation Group, Coventry University, Coventry, UK.

Objective: To undertake a comprehensive assessment of the strength of preferences among young people for attributes of emerging technologies for testing and treatment of asymptomatic chlamydia.

Design: Discrete choice experiment (DCE) with sequential mixed methods design. A staged approach to selection of attributes/levels included two literature reviews, focus groups with young people aged 16-24 years (n=21), experts' review (n=13) and narrative synthesis. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023663DOI Listing
January 2019
1 Read

Integrated Phosphoproteome and Transcriptome Analysis Reveals Chlamydia-Induced Epithelial-to-Mesenchymal Transition in Host Cells.

Cell Rep 2019 Jan;26(5):1286-1302.e8

Department of Molecular Biology, Max Planck Institute for Infection Biology, 10117 Berlin, Germany. Electronic address:

Chlamydia trachomatis (Ctr) causes a range of infectious diseases and is epidemiologically associated with cervical and ovarian cancers. To obtain a panoramic view of Ctr-induced signaling, we performed global phosphoproteomic and transcriptomic analyses. We identified numerous Ctr phosphoproteins and Ctr-regulated host phosphoproteins. Read More

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http://dx.doi.org/10.1016/j.celrep.2019.01.006DOI Listing
January 2019
4 Reads
7.207 Impact Factor

Ocular Chlamydia trachomatis infection: elimination with mass drug administration.

Expert Rev Anti Infect Ther 2019 Jan 30:1-12. Epub 2019 Jan 30.

a Dana Center for Preventive Ophthalmology , Johns Hopkins Medical Institutions , Baltimore , MD , USA.

Introduction: Ocular Chlamydia trachomatis infection, the causative agent for trachoma, is responsible for 1.9 million cases of visual loss worldwide. Mass Drug Administration (MDA) with azithromycin to entire trachoma-endemic districts is part of the World Health Organization's public health strategy for trachoma elimination. Read More

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http://dx.doi.org/10.1080/14787210.2019.1577136DOI Listing
January 2019

Binding of Elementary Bodies by the Opportunistic Fungal Pathogen or Soluble β-Glucan, Laminarin, Inhibits Infectivity.

Front Microbiol 2018 14;9:3270. Epub 2019 Jan 14.

Department of Biomedical Sciences, Quillen College of Medicine, East Tennessee State University, Johnson City, TN, United States.

Microbial interactions represent an understudied facet of human health and disease. In this study, the interactions that occur between and the opportunistic fungal pathogen, were investigated. is a common component of the oral and vaginal microbiota responsible for thrush and vaginal yeast infections. Read More

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http://dx.doi.org/10.3389/fmicb.2018.03270DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6339894PMC
January 2019
1 Read

Extragenital chlamydia infection among active-duty women in the United States Navy.

Mil Med Res 2019 Jan 29;6(1). Epub 2019 Jan 29.

Division of Infectious Diseases, Naval Medical Center San Diego, 34800 Bob Wilson Drive, Ste 201, San Diego, CA, 92134, USA.

Background: Pharyngeal and anorectal reservoirs of gonorrhea (GC) and chlamydia (CT) are increasingly recognized among heterosexual women. While a number of studies performed at sexually transmitted disease (STD) clinics have found a high prevalence of extragenital GC/CT infection, such screening is typically not offered during routine primary care visits for women. We sought to define the prevalence of and factors associated with extragenital GC/CT among women in the U. Read More

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http://dx.doi.org/10.1186/s40779-019-0193-xDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6350339PMC
January 2019
1 Read

Outbreak of Chlamydia pneumoniae Infections and X-ray-Confirmed Pneumonia in Army Trainees at Fort Leonard Wood, Missouri, 2014.

Mil Med 2019 Jan 23. Epub 2019 Jan 23.

US Army Public Health Center, Aberdeen Proving Ground, MD.

Introduction: Chlamydia pneumoniae (Cp) is a bacterium that causes pneumonia and other respiratory diseases. Fever may be present early but absent by time of presentation to clinic. Increases in X-ray-confirmed pneumonia (XCP) and laboratory-confirmed Cp infections were observed in new soldiers in training at Fort Leonard Wood (FLW), Missouri, early in 2014. Read More

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http://dx.doi.org/10.1093/milmed/usy402DOI Listing
January 2019
7 Reads

Treatment effectiveness of azithromycin and doxycycline in uncomplicated rectal and vaginal Chlamydia trachomatis infections in women: a multicentre observational study (FemCure).

Clin Infect Dis 2019 Jan 28. Epub 2019 Jan 28.

Department of Sexual Health, Infectious Diseases, and Environmental Health, Heerlen, South Limburg Public Health Service, The Netherlands.

Background: Rectal infections with Chlamydia trachomatis (CT) are prevalent in women visiting a sexually transmitted infection (STI) outpatient clinic, but it remains unclear what the most effective treatment is. We assessed the effectiveness of doxycycline and azithromycin for the treatment of rectal and vaginal chlamydia in women.

Methods: This study is part of a prospective multicentre cohort study (FemCure). Read More

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http://dx.doi.org/10.1093/cid/ciz050DOI Listing
January 2019

Community-level chlamydial serology for assessing trachoma elimination in trachoma-endemic Niger.

PLoS Negl Trop Dis 2019 Jan 28;13(1):e0007127. Epub 2019 Jan 28.

Divison of Parasitic Diseases and Malaria, Centers for Disease Prevention and Control, Atlanta, Georgia, United States of America.

Background: Program decision-making for trachoma elimination currently relies on conjunctival clinical signs. Antibody tests may provide additional information on the epidemiology of trachoma, particularly in regions where it is disappearing or elimination targets have been met.

Methods: A cluster-randomized trial of mass azithromycin distribution strategies for trachoma elimination was conducted over three years in a mesoendemic region of Niger. Read More

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http://dx.plos.org/10.1371/journal.pntd.0007127
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http://dx.doi.org/10.1371/journal.pntd.0007127DOI Listing
January 2019
4 Reads

M. pneumoniae and C. pneumoniae are no relevant pathogens in critically ill patients with hospital-acquired respiratory tract infections.

Infection 2019 Jan 28. Epub 2019 Jan 28.

Institute for Infectious Diseases and Infection Control, Jena University Hospital, Am Klinikum 1, 07747, Jena, Germany.

Purpose: To assess the incidence of Mycoplasma pneumoniae and Chlamydia pneumoniae in the pathogenesis of hospital-acquired respiratory tract infections (RTIs) in critically ill patients.

Methods: This is a retrospective cohort study of all ICU-patients ≥ 18 years with RTI who underwent conventional culture techniques and PCR testing for both M. pneumoniae and C. Read More

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http://dx.doi.org/10.1007/s15010-019-01273-xDOI Listing
January 2019
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Patient-Delivered Expedited Partner Therapy for Chlamydia trachomatis Infection Among Female Adolescents Using School-Based Health Centers.

J Pediatr Health Care 2019 Jan 22. Epub 2019 Jan 22.

Introduction: Expedited partner therapy (EPT) may reduce Chlamydia trachomatis reinfection. This pilot study was conducted to determine if female adolescents with C. trachomatis accept and deliver EPT to male sexual partners and whether it is associated with decreased C. Read More

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http://dx.doi.org/10.1016/j.pedhc.2018.11.008DOI Listing
January 2019
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Interaction of different Chlamydiae species with bovine spermatozoa.

BMC Microbiol 2019 Jan 25;19(1):23. Epub 2019 Jan 25.

Klinikum Veterinärmedizin, Clinic for Obstetrics, Gynecology and Andrology of Large and Small Animals, Justus-Liebig University Giessen, Frankfurter Strasse 106, 35392, Giessen, Germany.

Background: Interaction of spermatozoa and Chlamydiae spp. might contribute to reduced fertility in cattle. To proof this hypothesis, bovine semen was incubated with viable or heat inactivated Chlamydia (C. Read More

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https://bmcmicrobiol.biomedcentral.com/articles/10.1186/s128
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http://dx.doi.org/10.1186/s12866-019-1392-zDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347757PMC
January 2019
2 Reads

[Comparison of immunochromatographic (IC) and real-time polymerase chain reaction (Rt-PCR) tests for screening Neisseria gonorrhoeae, Chlamydia trachomatis, Ureaplasma spp. and Mycoplasma spp. in HIV-infected men].

Mikrobiyol Bul 2019 Jan;53(1):37-42

Hacettepe University Faculty of Medicine, Department of Infectious Diseases and Clinical Microbiology, Ankara, Turkey.

Laboratory testing is critical for sexually transmitted infections (STIs) as most of the infected people usually have no symptoms. It is known that having HIV and STI coinfection increases the risk of HIV transmission. Sensitive tests are required for the infection control. Read More

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http://dx.doi.org/10.5578/mb.67694DOI Listing
January 2019
3 Reads

Antibiotics for treating urogenital Chlamydia trachomatis infection in men and non-pregnant women.

Cochrane Database Syst Rev 2019 Jan 25;1:CD010871. Epub 2019 Jan 25.

Clinical Research Institute, Faculty of Medicine, Universidad Nacional de Colombia, Bogota, Colombia.

Background: The genital infection caused by Chlamydia trachomatis (CT) is a common sexually transmitted infection (STI) globally. The infection is mainly asymptomatic in women, thus it can produce infertility and chronic pelvic pain. In men infection is mainly symptomatic, but can evolve to prostatitis. Read More

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http://dx.doi.org/10.1002/14651858.CD010871.pub2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6353232PMC
January 2019
2 Reads

Developing non-invasive methodologies to assess koala population health through detecting Chlamydia from scats.

Mol Ecol Resour 2019 Jan 25. Epub 2019 Jan 25.

Global Change Ecology Research Group, University of the Sunshine Coast, 90 Sippy Downs Drive, Sippy Downs, Queensland, 4556, Australia.

Wildlife diseases are a recognized driver of global biodiversity loss, have substantial economic impacts, and are increasingly becoming a threat to human health. Disease surveillance is critical but remains difficult in the wild due to the substantial costs and potential biases associated with most disease detection methods. Non-invasive scat surveys have been proposed as a health monitoring methodology to overcome some of these limitations. Read More

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http://doi.wiley.com/10.1111/1755-0998.12999
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http://dx.doi.org/10.1111/1755-0998.12999DOI Listing
January 2019
4 Reads