1,563 results match your criteria Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih[Journal]


Pancreatic Cancer Presents as Inguinal Mass: A Case Report and Literature Review.

Authors:
Haiyan Zhu Min Dai

Chin Med Sci J 2020 Mar;35(1):101-104

Department of General Surgery, Haian Hospital Affiliated to Nantong University, Jiangsu 226600, China.

A 70-year-old male presenting with a mass in the right inguinal area was treated with surgery, and was diagnosed pathologically as spermatic cord metastasis of pancreatic cancer. He was given systemic chemotherapy. Unfortunately, he died of ascites and cachexia three months later. Read More

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http://dx.doi.org/10.24920/003566DOI Listing

Acute Pancreatitis Complicated by Sheehan's Syndrome: A Case Report and Literature Review.

Chin Med Sci J 2020 Mar;35(1):95-100

Department of Gastroenterology, The First Affiliated Hospital of Jinan University, Guangzhou 510632, China.

A 44-year-old woman was transferred to the ICU of the First Affiliated Hospital of Jinan University for 2 days of persistent epigastric pain and 7 hours of unconsciousness. Her admission diagnosis was severe acute necrotizing pancreatitis (hypertriglyceridemia type) with multiple organ dysfunctions. The results of CT revealed a small area of necrotizing pancreatitis, which was not consistent with the severe clinical manifestations. Read More

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http://dx.doi.org/10.24920/003574DOI Listing

Immediate Nipple Reconstruction Following Breast Reduction.

Chin Med Sci J 2020 Mar;35(1):92-94

Breast Plastic and Reconstructive Surgery Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100144, China.

Necrosis of nipple-areola complex is one of the major complications of breast reduction in gigatomastia. We present a case study of a 32-year-old patient with severe gigantomastia, who required an immediate nipple reconstruction during breast reduction. The final reconstruction was satisfactory. Read More

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http://dx.doi.org/10.24920/003581DOI Listing

Association Between Homocysteine Level and Methylenetetrahydrofolate Reductase Gene Polymorphisms in Type 2 Diabetes Accompanied by Dyslipidemia.

Chin Med Sci J 2020 Mar;35(1):85-91

Department of Pharmacy, Shandong Provincial Qianfoshan Hospital, Jinan 250014, China.

Objective To investigate the association between total homocysteine (tHcy) level in plasma and methylenetetrahydrofolate reductase () C677T and A1298C genetic polymorphisms in a Chinese Han nationality population with type 2 diabetes mellitus (T2DM) accompanied by dyslipidemia. Methods This case-control study enrolled T2DM patients with dyslipidemia and without dyslipidemia respectively. Sanger dideoxy-mediated chain-termination method was used to detect the gene polymorphisms of C677T and A1298C. Read More

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http://dx.doi.org/10.24920/003532DOI Listing

Methylenetrahydrofolate Reductase Gene C677T Polymorphism and Diabetic Retinopathy: a Meta-Analysis.

Chin Med Sci J 2020 Mar;35(1):71-84

Beijing Tongren Eye Center & Beijing Ophthalmology and Visual Sciences Key Laboratory, Beijing Tongren Hospital, Capital Medical University, Beijing 100730, China.

Objective To investigate the association between the methylenetetrahydrofolate reductase gene C677T ( C677T) polymorphism and diabetic retinopathy (DR). Methods A total of 6971 subjects including 2707 DR patients and 4264 controls from 23 studies were enrolled in the study. A random-effects model was applied to estimate the overall effects and the stratified effects of the C677T polymorphism on the risk of DR, and study quality was also assessed. Read More

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http://dx.doi.org/10.24920/003535DOI Listing

Acute Myocardial Infarction After Tranexamic Acid: Review of Published Case Reports.

Chin Med Sci J 2020 Mar;35(1):65-70

Department of Anesthesiology, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.

Objective To summarize cases of acute myocardial infarction (AMI) after tranexamic acid (TXA) administration. Methods Electronic databases were searched to identify all case reports presenting AMI after use of TXA. Two authors independently extracted data of patients' manifestation, examinations, medical history, treatment and outcome. Read More

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http://dx.doi.org/10.24920/003596DOI Listing

Transcriptional Profile Alteration of Peripheral Blood in Chronic Hypoxia.

Chin Med Sci J 2020 Mar;35(1):54-64

State Key Laboratory of Cardiovascular Diseases, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100037, China.

Objective Many physiological and pathological conditions, including cyanotic congenital heart diseases (CCHD), are accompanied by chronic hypoxia, which might interfere with the transcription process. However, the transcriptome profile in peripheral blood under hypoxia is still unidentified. The present work aimed to explore the transcriptional profile alteration of peripheral blood in chronic hypoxia. Read More

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http://dx.doi.org/10.24920/003598DOI Listing

Vascular Transcriptome Profiling Reveals Aging-Related Genes in Angiotensin Ⅱ-Induced Hypertensive Mouse Aortas.

Chin Med Sci J 2020 Mar;35(1):43-53

State Key Laboratory of Medical Molecular Biology, Department of Biochemistry and Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College, Beijing 100005, China.

Objective Angiotensin Ⅱ (Ang Ⅱ)-induced vascular damage is a major risk of hypertension. However, the underlying molecular mechanism of AngⅡ-induced vascular damage is still unclear. In this study, we explored the novel mechanism associated with Ang II-induced hypertension. Read More

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http://dx.doi.org/10.24920/003709DOI Listing

NF-κB Inhibitor Parthenolide Promotes Renal Tubules Albumin Uptake in Type 2 Diabetic Nephropathy.

Chin Med Sci J 2020 Mar;35(1):31-42

Department of Nephrology, Peking Union Medical College Hospital, Chinese Academy of Medicine Sciences & Peking Union Medical College, Beijing 100730, China.

Objective Injured tubular reabsorption is highlighted as one of the causes of increased albuminuria in the early stage of diabetic nephropathy; however, the underlying mechanism has not been fully elucidated. In this study, we aimed to explore whether reducing inflammation and remodeling the insulin signaling pathway could improve albumin uptake of renal tubules. Methods 8-week-old male db/db mice (=8), a type 2 diabetic nephropathy model, administered with nuclear factor kappa-B (NF-κB) inhibitor parthenolide (PTN, 1 mg/kg) intraperitoneally every other day for 8 weeks, were as the treatment group. Read More

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http://dx.doi.org/10.24920/003573DOI Listing

Lrrc34 Is Highly Expressed in SSCs and Is Necessary for SSC Expansion .

Chin Med Sci J 2020 Mar;35(1):20-30

Department of Biochemistry and Molecular Biology, State Key Laboratory of Medical Molecular Biology, Institute of Basic Medical Sciences Chinese Academy of Medical Sciences & School of Basic Medicine Peking Union Medical College, Beijing 100005, China.

Objective To discover critical genes contributing to the stemness and maintenance of spermatogonial stem cells (SSCs) and provide new insights into the function of the leucine-rich repeat (LRR) family member Lrrc34 (leucine-rich repeat-containing 34) in SSCs from mice. Methods Bioinformatic methods, including differentially expressed gene (DEG), gene ontology (GO) enrichment and Kyoto Encyclopedia of Genes and Genomes (KEGG) pathway analyses, were used to uncover latent pluripotency-related genes. Reverse transcription-polymerase chain reaction (RT-PCR) and immunofluorescence analyses were utilized to verify the mRNA and protein expression levels, respectively. Read More

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http://dx.doi.org/10.24920/003680DOI Listing

Early Warning of Acute Altitude Sickness by Physiological Variables and Noninvasive Cardiovascular Indicators.

Chin Med Sci J 2020 Mar;35(1):13-19

Department of Cardiology, Chinese PLA General Hospital, Beijing 100853, China.

Objective To examine if the variations at sea level would be able to predict subsequent susceptibility to acute altitude sickness in subjects upon a rapid ascent to high altitude. Methods One hundred and six Han nationality male individuals were recruited to this research. Dynamic electrocardiogram, treadmill exercise test, echocardiography, routine blood examination and biochemical analysis were performed when subjects at sea level and entering the plateau respectively. Read More

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http://dx.doi.org/10.24920/003552DOI Listing

Chinese Expert Consensus on Perioperative Medication in Laser Corneal Refractive Surgeries (2019).

Authors:
Ying Li Yan Wang

Chin Med Sci J 2020 Mar;35(1):1-12

Tianjin Eye Hospital, Nankai University Eye Hospital, Tianjin 300020, China.

Laser corneal refractive surgery has become an important treatment to correct ametropia in recent years. Rational medication in the perioperative period is essential to ensure the success of the surgery and to reduce complications. However, in this area there has been no consistent understanding and unified application guide across the world. Read More

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http://dx.doi.org/10.24920/003712DOI Listing

Expert Recommendations for Tracheal Intubation in Critically ill Patients with Noval Coronavirus Disease 2019.

Chin Med Sci J 2020 Feb 27. Epub 2020 Feb 27.

Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences, Beijing, 100730 China.

Coronavirus Disease 2019 (COVID-19), caused by a novel coronavirus (SARS-CoV-2), is a highly contagious disease. It firstly appeared in Wuhan, Hubei province of China in December 2019. During the next two months, it moved rapidly throughout China and spread to multiple countries through infected persons travelling by air. Read More

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http://dx.doi.org/10.24920/003724DOI Listing
February 2020

Association between 1 Homozygous Deletion and Risk of Pancreatic Cancer: A Meta Analysis.

Chin Med Sci J 2019 Sep;34(3):205-210

China Medical University, Shenyang 110013, China.

Objective To clarify the possible association of 1 homozygous deletion with the susceptibility to pancreatic cancer. Methods We searched PubMed database, Chinese Journal Full Text Database (CNKI), and EMBASE to find the eligible studies published up to April 18, 2018 for evaluating the relationship between 1 homozygous deletion and pancreatic cancer. The frequency of null genotype for 1 between the pancreatic cancer group and the healthy control group was compared with - test, and odds ratios (s) value and 95% confidence interval (95% ) were calculated. Read More

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http://dx.doi.org/10.24920/003490DOI Listing
September 2019

Research on the Antitumor Compounds from .

Authors:

Chin Med Sci J 2019 Sep;34(3):232

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September 2019

Artificial Musk R&D and Manufacturing.

Authors:

Chin Med Sci J 2019 Sep;34(3):230-231

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September 2019

Management of an Adult with Goodpasture's Syndrome Following Brain Trauma with Extracorporeal Membrane Oxygenation: A Case Report.

Chin Med Sci J 2019 Sep;34(3):226-229

Institute of Clinical Nutrition, Guangzhou Red Cross Hospital, Medical College, Jinan University, Guangzhou 510220, China.

A 22-year-old man suffered from acute pulmonary hemorrhage and deteriorated renal function occurred within 3 days after traumatic brain injury. Mechanical ventilation cannot correct his severe hypoxemia, therefore, venoarterial extracorporeal membrane oxygenation (VA-ECMO) support was initiated and finally resolved his hypoxemia. Concomitantly, continuous renal replacement therapy was performed to improve his kidney function. Read More

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http://dx.doi.org/10.24920/003478DOI Listing
September 2019
2 Reads

Transvaginal Reduction of a Heterotopic Cornual Pregnancy with Conservation of Intrauterine Pregnancy.

Chin Med Sci J 2019 Sep;34(3):221-225

Center of Reproductive Medicine, Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, Shanghai 201204, China.

Here we report a case of heterotopic cornual pregnancy after fertilization who was diagnosed at 6 weeks after frozen embryos transfer. The heterotopic pregnancy was successfully terminated by transvaginal ultrasound-guided selective fetal reduction. At 38+1 weeks, she underwent a cesarean section and delivered a healthy 3300 g male infant with Apgar score of 10-10' evaluated at 1 min and 5 min. Read More

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http://dx.doi.org/10.24920/003485DOI Listing
September 2019
1 Read

Research Progress on Diagnosis and Treatment of Chronic Osteomyelitis.

Chin Med Sci J 2019 Sep;34(3):211-220

Key Laboratory of Emergency and Trauma of Ministry of Education, Hainan Medical University, Haikou 571199, China.

We review the representatives literatures on chronic osteomyelitis, sum up the new insights in recent years into diagnostic options and treatment regimens, analyze the advantages and disadvantages of various diagnostic approaches and treatment strategies, and propose areas of interest to make current diagnostic and treatment strategies more specific. Read More

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http://dx.doi.org/10.24920/003493DOI Listing
September 2019
1 Read

IL-36 Promotes Inflammatory Activity and Inhibits Differentiation of Keratinocytes .

Chin Med Sci J 2019 Sep;34(3):199-204

Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Objective Psoriasis is an immune-mediated inflammatory disease. Despite advances in the study of its pathogenesis, the exact development mechanism of psoriasis remains to be fully elucidated. Hyperproliferative epidermis plays a crucial role in psoriasis. Read More

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http://dx.doi.org/10.24920/003489DOI Listing
September 2019
1 Read

Value of CT-Angiography in the Emergency Management of Severe Hemoptysis.

Chin Med Sci J 2019 Sep;34(3):194-198

Department of Radiology, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing 100730, China.

Objective To depict imaging anatomy of bronchial artery (BA) using multidetector CT-angiography (MDCTA) and evaluate the value of MDCTA for management of hemoptysis patients requiring admission to emergency room. Methods We retrospectively studied the clinical and radiological data of patients with severe hemoptysis (≥100 ml of expectorated blood in a 24-hour period) requiring admission to emergency room from Jan 1, 2013 to Dec 31, 2015. Patients' images of MDCTA, treatment modalities, and outcome were discussed. Read More

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http://dx.doi.org/10.24920/003482DOI Listing
September 2019
2 Reads

Downregulation of iASPP Expression Suppresses Proliferation, Invasion and Increases Chemosensitivity to Paclitaxel of Head and Neck Squamous Cell Carcinoma .

Chin Med Sci J 2019 Sep;34(3):184-193

Department of Pharmacy, , Xiangya Hospital, Central South University, Changsha 410008, China.

Objective Our previous study has revealed that iASPP is elevated in human head and neck squamous cell carcinoma (HNSCC) and iASPP overexpression signifcantly correlates with tumor malignant progression and poor survival of HNSCC. This study investigated the function of iASPP playing in proliferation and invasion of HNSCC . Methods HNSCC cell line Tu686 transfected with Lentiviral vector-mediated iASPP-specific shRNA and control shRNA were named the shRNA-iASPP group and shRNA-NC group, respectively. Read More

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http://dx.doi.org/10.24920/003558DOI Listing
September 2019
1 Read

Five-year Clinical Outcomes of CAD Patients Complicated with Diabetes after StentBoost-optimized Percutaneous Coronary Intervention.

Chin Med Sci J 2019 Sep;34(3):177-183

Department of Cardiology, The Fourth Medical Center of Chinese PLA General Hospital, Beijing 100048, China.

Objective To evaluate the instant effects and five-year clinical outcomes of coronary artery disease patients complicated with diabetes mellitus after StentBoost-optimized percutaneous coronary intervention (PCI). Methods From March 2009 to July 2010, 184 patients undergoing PCI at our hospital were found stent underexpansion or malapposition by StentBoost after stents implantation and were divided into the diabetic (=73, 39.67%) and the non-diabetic group (=111, 60. Read More

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http://dx.doi.org/10.24920/003496DOI Listing
September 2019
3 Reads

Identification of CDK6 and RHOU in Serum Exosome as Biomarkers for the Invasiveness of Non-functioning Pituitary Adenoma.

Chin Med Sci J 2019 Sep;34(3):168-176

State Key Laboratory of Medical Molecular Biology & Key Laboratory of RNA and Hematopoietic Regulation & Department of Biochemistry, Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences & School of Basic Medicine, Peking Union Medical College, Beijing 100005, China.

Objective To explore circulating biomarkers for screening the invasiveness of non-functioning pituitary adenomas (NF-PAs). Methods The exosomal RNAs were extracted from serum of patients with invasive NF-PA (INF-PA) or noninvasive NF-PA (NNF-PA). Droplet digital PCR was adapted to detect the mRNA expression of candidate genes related to tumor progression or invasion, such as cyclin dependent kinase 6 (CDK6), ras homolog family member U (RHOU), and spire type actin nucleation factor 2 (SPIRE2). Read More

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http://dx.doi.org/10.24920/003585DOI Listing
September 2019

Regional Differences of the Urinary Proteomes in Healthy Chinese Individuals.

Chin Med Sci J 2019 Sep;34(3):157-167

Department of Biochemistry and Molecular Biology, Gene Engineering Drug and Biotechnology Beijing Key Laboratory, Beijing Normal University, Beijing 100875, China.

Objective Urine is a promising biomarker source for clinical proteomics studies. Regional physiological differences are common in multi-center clinical studies. In this study, we investigate whether significant differences are present in the urinary proteomes of individuals from different regions in China. Read More

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http://dx.doi.org/10.24920/003504DOI Listing
September 2019
1 Read

Integrative Analysis Confirmed the Association between Osteoprotegerin and Osteoporosis.

Chin Med Sci J 2019 Jun;34(2):147-156

Center for Genetic Epidemiology and Genomics, School of Public Health, Jiangsu Key Laboratory of Preventive and Translational Medicine for Geriatric Diseases, Medical College of Soochow University, Suzhou, Jiangsu 215123, China.

Objective This study aimed to verify the association between osteoprotegerin gene () and its variants with osteoporosis (OP) by performing integrative analysis.Methods We used the KGG software to perform gene-based association analysis, which integrated all publicly available single-nucleotide polymorphism (SNP)-based values and obtained an overall value for the . The significant SNPs were screened for expression quantitative trait loci (eQTLs). Read More

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http://dx.doi.org/10.24920/003466DOI Listing
June 2019
2 Reads

A Survey of Surgical Patient's Perception about Anesthesiologist in a Large Scale Comprehensive Hospital in China.

Chin Med Sci J 2019 Jun;34(2):140-146

Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Objectives This study aim to evaluate patient's perception about anesthesiologists' job roles and investigate their expectations for anesthesia care.Methods We designed a self-administered questionnaire for this cross-sectional survey study and delivered questionnaire forms to adult in-patients who were scheduled for elective surgery before pre-operative anesthetic visit the day before surgery. We collected information of respondents' demographic data, education background, health literacy and previous experience of anesthesia, perception of anesthesiologist's job, the expectation on anesthesia care. Read More

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http://dx.doi.org/10.24920/003503DOI Listing

Medical Knowledge Extraction and Analysis from Electronic Medical Records Using Deep Learning.

Chin Med Sci J 2019 Jun;34(2):133-139

Engineering Research Center of Mobile Health Management, Ministry of Education, Hangzhou Normal University, Hangzhou 311121, China.

Objectives Medical knowledge extraction (MKE) plays a key role in natural language processing (NLP) research in electronic medical records (EMR), which are the important digital carriers for recording medical activities of patients. Named entity recognition (NER) and medical relation extraction (MRE) are two basic tasks of MKE. This study aims to improve the recognition accuracy of these two tasks by exploring deep learning methods. Read More

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http://dx.doi.org/10.24920/003589DOI Listing

A Survey on Intelligent Screening for Diabetic Retinopathy.

Chin Med Sci J 2019 Jun;34(2):120-132

School of Computing Science and Engineering;Hunan Province Engineering Technology Research Center of Computer Vision and Intelligent Medical Treatment, Changsha 410083, China.

Diabetic retinopathy (DR) is one of the leading causes of vision loss and can be effectively avoided by screening, early diagnosis and treatment. In order to increase the universality and efficiency of DR screening, many efforts have been invested in developing intelligent screening, and there have been great advances. In this paper, we survey DR screening from four perspectives: 1) public color fundus image datasets of DR; 2) DR classification and related lesion-extraction approaches; 3) existing computer-aided systems for DR screening; and 4) existing issues, challenges, and research trends. Read More

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http://dx.doi.org/10.24920/003587DOI Listing

Multi-Atlas Based Methods in Brain MR Image Segmentation.

Chin Med Sci J 2019 Jun;34(2):110-119

College of Computer Science and Technology, Nanjing University of Aeronautics and Astronautics, MIIT Key Laboratory of Pattern Analysis and Machine Intelligence, Nanjing 211106, China.

Brain region-of-interesting (ROI) segmentation is an important prerequisite step for many computer-aid brain disease analyses. However, the human brain has the complicated anatomical structure. Meanwhile, the brain MR images often suffer from the low intensity contrast around the boundary of ROIs, large inter-subject variance and large inner-subject variance. Read More

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http://dx.doi.org/10.24920/003576DOI Listing
June 2019
2 Reads

Application of Mixed Reality Technology in Visualization of Medical Operations.

Chin Med Sci J 2019 Jun;34(2):103-109

Educational Technology Center, The PLA General Hospital, 100853 Beijing, China.

With the continuous progress of virtual simulation technology, medical surgery visualization system has been developed from two-dimensional to three-dimensional, from digital to network and intelligentization. The visualization system with mixed reality technology will also be used in all stage of medical surgery, such as case discussion, surgical planning, intraoperative guidance, post-operative evaluation, rehabilitation, so as to further promote high intelligence, high precision of medical surgery, and consequently improve effectiveness of treatment and quality of medical service. This paper discusses the composition and technical characteristics of medical operation visualization system based on mixed reality technology, and introduces some typical applications of mixed reality technology in medical operation visualization, which provides a new perspective for the application of mixed technology in medical surgery. Read More

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http://dx.doi.org/10.24920/003564DOI Listing

Constructing Large Scale Cohort for Clinical Study on Heart Failure with Electronic Health Record in Regional Healthcare Platform: Challenges and Strategies in Data Reuse.

Chin Med Sci J 2019 Jun;34(2):90-102

Shanghai Hospital Development Center, Shanghai 200041, China.

Regional healthcare platforms collect clinical data from hospitals in specific areas for the purpose of healthcare management. It is a common requirement to reuse the data for clinical research. However, we have to face challenges like the inconsistence of terminology in electronic health records (EHR) and the complexities in data quality and data formats in regional healthcare platform. Read More

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http://dx.doi.org/10.24920/003579DOI Listing
June 2019
3 Reads

Collaborations of Industry, Academia, Research and Application Improve the Healthy Development of Medical Imaging Artificial Intelligence Industry in China.

Chin Med Sci J 2019 Jun;34(2):84-88

Department of Radiology, Changzheng Hospital, Naval Medical University (Second Military Medical University), Shanghai 200003, China.

In recent years, artificial intelligence (AI) has developed rapidly in the field of medical imaging. However, the collaborations among hospitals, research institutes and enterprises are insufficient at the present, and there are various issues in technological transformation and value landing of products in this area. To solve the core problems in the developmental path of medical imaging AI, the Chinese Innovative Alliance of Industry, Education, Research and Application of Artificial Intelligence for Medical Imaging compiled the . Read More

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http://dx.doi.org/10.24920/003619DOI Listing

Artificial Intelligence in Healthcare and Medicine: Promises, Ethical Challenges and Governance.

Authors:
Jian Guan

Chin Med Sci J 2019 Jun;34(2):76-83

Clinical Center, the National Scientific Data Sharing Platform for Population and Health.

Artificial intelligence (AI) is rapidly being applied to a wide range of fields, including medicine, and has been considered as an approach that may augment or substitute human professionals in primary healthcare. However, AI also raises several challenges and ethical concerns. In this article, the author investigates and discusses three aspects of AI in medicine and healthcare: the application and promises of AI, special ethical concerns pertaining to AI in some frontier fields, and suggestive ethical governance systems. Read More

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http://dx.doi.org/10.24920/003611DOI Listing

The Artificial Intelligence-Enabled Medical Imaging: Today and Its Future.

Chin Med Sci J 2019 Jun;34(2):71-75

Institute for Medical Imaging Technology, School of Biomedical Engineering, Shanghai Jiao Tong University, Shanghai 200030, China.

Medical imaging is now being reshaped by artificial intelligence (AI) and progressing rapidly toward future. In this article, we review the recent progress of AI-enabled medical imaging. Firstly, we briefly review the background about AI in its way of evolution. Read More

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http://dx.doi.org/10.24920/003615DOI Listing

The Next Era: Flourish of National Health Care & Medicine with the World Leading Artificial Intelligence.

Authors:
Jian Wu

Chin Med Sci J 2019 Jun;34(2):69-70

College of Computer Science and Technology, Zhejiang University, Hangzhou 310027, China.

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http://dx.doi.org/10.24920/003628DOI Listing
June 2019
1 Read

Vertebral Artery Dissection Probably Caused by Massage: A Case Report.

Chin Med Sci J 2019 Mar;34(1):65-68

Medical Imaging Center, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China.

MASSAGE has been recommended to more people as an adjunct to health care. We illustrate a case of vertebral artery dissection (VAD) probably caused by massage that almost resulted in the patient's death. The patient experienced sudden cardiac arrest and paralysis. Read More

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http://dx.doi.org/10.24920/003480DOI Listing
March 2019
16 Reads

Successful Treatment of Severe Heparin-induced Thrombocytopenia with Intravenous Immunoglobulin, Platelet Transfusion and Rivaroxaban: A Case Report.

Chin Med Sci J 2019 Mar;34(1):60-64

Department of Hematology, The 2nd Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang 325027, China.

Heparin-induced thrombocytopenia (HIT) is a relatively infrequent complication of heparin administration. HIT can cause devastating thrombosis, making it one of the most serious adverse drug reactions encountered in clinical practice. We successfully treated a case of severe HIT presenting with thrombosis and life-threatening bleeding complications with intravenous immunoglobulin (IVIG), platelet transfusion and oral anticoagulant Rivaroxaban. Read More

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http://dx.doi.org/10.24920/003462DOI Listing
March 2019
7 Reads

Bilateral Peripheral Facial Paralysis Combined with HIV Meningitis During Acute HIV-1 Infection: A Case Report.

Chin Med Sci J 2019 Mar;34(1):55-59

Department of Dermatology and Venereology, Beijing Ditan Hospital Affiliated to Capital Medical University, Beijing 100015, China.

Here we reported a Chinese case of bilateral peripheral facial paralysis (PFP) in human immunodeficiency virusc (HIV) infected population. A 38-year-old homosexual male patient was referred to our hospital for bilateral facial paralysis. 21 days prior to admission he had developed high fever, chills, headache, fatigue, general malaise, nausea and vomiting. Read More

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http://dx.doi.org/10.24920/003460DOI Listing
March 2019
21 Reads

Humanistic Spirit Contained in Traditional Chinese Medicine should Be Valued.

Chin Med Sci J 2019 Mar;34(1):51-54

Department of Traditional Chinese Medicine, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100730, China.

Medicine is a science studying human's health and diseases as well as the regularity between them. Its research subject is human, who possess natural attribute, psychological attribute and social attribute. Therefore, medicine is bound to possess humanistic attribute. Read More

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http://dx.doi.org/10.24920/003486DOI Listing
March 2019
1 Read

Application and Progress of Texture Analysis in the Therapeutic Effect Prediction and Prognosis of Neoadjuvant Chemoradiotherapy for Colorectal Cancer.

Chin Med Sci J 2019 Mar;34(1):45-50

Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100730, China.

Colorectal cancer is one of the most common malignant tumors, and the morbidity and mortality are increasing gradually over the last years in China. Neoadjuvant chemoradiotherapy (nCRT) is currently applied to the treatment of colorectal cancer patients, and it is helpful to improve the prognosis. The sensitivity of patients to nCRT is different due to individual differences. Read More

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http://dx.doi.org/10.24920/003572DOI Listing
March 2019
2 Reads

Prediction of Hidden Blood Loss During Posterior Spinal Surgery.

Chin Med Sci J 2019 Mar;34(1):38-44

Department of Anesthesiology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Objective Identification of the risk factors for extraordinary hidden blood loss (HBL) could clarify the underlying causes and provide more appropriate management. This study aims to identify the predictors of HBL in spinal surgery.Methods Medical records were retrospectively retrieved to collect the data of patients who undergoing posterior thoracic and lumbar fusion surgery or scoliosis surgery. Read More

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http://dx.doi.org/10.24920/003463DOI Listing
March 2019
2 Reads

Value of Magnetic Resonance Imaging Texture Analysis in the Differential Diagnosis of Benign and Malignant Breast Tumors.

Chin Med Sci J 2019 Mar;34(1):33-37

Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China.

Objective To investigate the difference in texture features on diffusion weighted imaging (DWI) images between breast benign and malignant tumors.Methods Patients including 56 with mass-like breast cancer, 16 with breast fibroadenoma, and 4 with intraductal papilloma of breast treated in the Hainan Hospital of Chinese PLA General Hospital were retrospectively enrolled in this study, and allocated to the benign group (20 patients) and the malignant group (56 patients) according to the post-surgically pathological results. Texture analysis was performed on axial DWI images, and five characteristic parameters including Angular Second Moment (ASM), Contrast, Correlation, Inverse Difference Moment (IDM), and Entropy were calculated. Read More

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http://dx.doi.org/10.24920/003516DOI Listing
March 2019
5 Reads

Value of Texture Analysis on Gadoxetic Acid-enhanced MR for Detecting Liver Fibrosis in a Rat Model.

Chin Med Sci J 2019 Mar;34(1):24-32

Department of Radiology, Peking Union Medical College Hospital, Peking Union Medical College & Chinese Academy of Medical Sciences, Beijing 100730, China.

Objective To explore the ability of texture analysis of gadoxetic acid-enhanced magnetic resonance imaging (MRI) T1 mapping images, as well as T1-weighted (T1W), T2-weighted (T2W) and apparent diffusion coefficient (ADC) maps for distinguishing between varying degrees of hepatic fibrosis in an experimental rat model.Methods Liver fibrosis in rats was induced by carbon tetrachloride intraperitoneal injection for 4-12 weeks (n=30). In the control group (n=10) normal saline was applied. Read More

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http://dx.doi.org/10.24920/003562DOI Listing
March 2019
3 Reads

MRI Histogram Texture Feature Analysis of the Optic Nerve in the Patients with Optic Neuritis.

Chin Med Sci J 2019 Mar;34(1):18-23

Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China.

Objective To evaluate the optic nerve impairment using MRI histogram texture analysis in the patients with optic neuritis.Methods The study included 60 patients with optic neuritis and 20 normal controls. The coronal T2 weighted imaging (T2WI) with fat saturation and enhanced T1 weighted imaging (T1WI) were performed to evaluate the optic nerve. Read More

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http://dx.doi.org/10.24920/003507DOI Listing
March 2019
5 Reads

Differential Diagnostic Value of Texture Feature Analysis of Magnetic Resonance T2 Weighted Imaging between Glioblastoma and Primary Central Neural System Lymphoma.

Chin Med Sci J 2019 Mar;34(1):10-17

Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China.

Objective To investigate the difference in tumor conventional imaging findings and texture features on T2 weighted images between glioblastoma and primary central neural system (CNS) lymphoma.Methods The pre-operative MRI data of 81 patients with glioblastoma and 28 patients with primary CNS lymphoma admitted to the Chinese PLA General Hospital and Hainan Hospital of Chinese PLA General Hospital were retrospectively collected. All patients underwent plain MR imaging and enhanced T1 weighted imaging to visualize imaging features of lesions. Read More

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http://dx.doi.org/10.24920/003548DOI Listing
March 2019
21 Reads

Value of Texture Analysis of Intravoxel Incoherent Motion Parameters in Differential Diagnosis of Pancreatic Neuroendocrine Tumor and Pancreatic Adenocarcinoma.

Chin Med Sci J 2019 Mar;34(1):1-9

Department of Radiology, Hainan Hospital of Chinese PLA General Hospital, Sanya, Hainan 572013, China.

Objective To evaluate the value of texture features derived from intravoxel incoherent motion (IVIM) parameters for differentiating pancreatic neuroendocrine tumor (pNET) from pancreatic adenocarcinoma (PAC).Methods Eighteen patients with pNET and 32 patients with PAC were retrospectively enrolled in this study. All patients underwent diffusion-weighted imaging with 10 b values used (from 0 to 800 s/mm ). Read More

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http://dx.doi.org/10.24920/003531DOI Listing
March 2019
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An Early Pregnant Chinese Woman with Cerebral Venous Sinus Thrombosis Succeeding in Induction of Labor in the Second Trimester.

Chin Med Sci J 2018 Dec;33(4):267-271

Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

Cerebral venous sinus thrombosis (CVST) is a rare condition in early pregnancy. A 22-year-old Chinese woman at 10 weeks of pregnancy requested induced abortion and was diagnosed as CVST for a severe headache accompanying with nausea and vomiting. The patient was treated successfully with anticoagulation, followed by amniocentesis, and finally succeeded in induction of labor safely. Read More

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http://dx.doi.org/10.24920/31806DOI Listing
December 2018
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Combined Effects of Chronic Obstructive Pulmonary Disease and Depression on Spatial Memory in Old Rats.

Chin Med Sci J 2018 Dec;33(4):260-266

Department of Geriatrics,Hangzhou First People's Hospital, Hangzhou 310006, China.

Objective To investigate the combined effects of chronic obstructive pulmonary disease (COPD) and depression on spatial memory in old rats, aiming to better understand the comorbidity of the two diseases in geriatric patients. Methods The SD rats were assigned into five groups: adult control group (n=6), elderly control group (n=6), elderly COPD group (n=6), elderly depression group (n=6) and elderly COPD with depression group (n=6). Smoking and chronic unpredictable mild stress (CUMS) with solitary support were used to induce COPD model, depression model, respectively, and the both were applied for the comorbidity model. Read More

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http://dx.doi.org/10.24920/003470DOI Listing
December 2018
3 Reads