722,672 results match your criteria Chinese medical sciences journal = Chung-kuo i hsueeh k'o hsueeh tsa chih / Chinese Academy of Medical Sciences[Journal]
Cell Physiol Biochem 2018 Dec 6;51(5):2148-2159. Epub 2018 Dec 6.
Minimally Invasive Treatment Center, Fudan University Shanghai Cancer Center, Shanghai,
Background/aims: Although oxaliplatin is one of the most effective chemotherapeutic drugs used to treat colorectal cancer (CRC), long-term administration usually induces acquired drug resistance during the course of treatment. Thus, there is an urgent need to explore novel strategies to improve the efficiency of cancer therapy. The aim of this study was to explore the effect of microRNA-122 (miR-122) on reversing oxaliplatin resistance in CRC. Read More
Cell Physiol Biochem 2018 Dec 6;51(5):2073-2084. Epub 2018 Dec 6.
Faculty of Information Technology & State Key Laboratory of Quality Research in Chinese Medicines, Macau University of Science and Technology, Macau, China.
Background/aims: One of the most important impacts of personalized medicine is the connection between patients' genotypes and their drug responses. Despite a series of studies exploring this relationship, the predictive ability of such analyses still needs to be strengthened.
Methods: Here we present the Lq penalized network-constrained logistic regression (Lq-NLR) method to meet this need, in which the predictors are integrated into the gene expression data and biological network knowledge and are combined with a more aggressive penalty function. Read More
J Environ Manage 2018 Dec 3;232:692-701. Epub 2018 Dec 3.
Chinese Academy of Environmental Planning, Beijing, China.
Suppliers' adoption of sustainable practices plays a critical role for global companies to improve environmental performance. Based on the absorptive capacity theory, this study empirically explores how suppliers' knowledge bases and power relationships influence their adoption of sustainability practices. A longitudinal case study with eight suppliers has been conducted. Read More
Water Res 2018 Nov 14;149:596-606. Epub 2018 Nov 14.
State Key Laboratory of Environmental Aquatic Chemistry, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, China; National Engineering Laboratory for VOCs Pollution Control Material & Technology, University of Chinese Academy of Sciences, Beijing, 101408, China. Electronic address:
Wastewater treatment plants (WWTPs) are major sources of airborne bacteria, which could pose health risks to WWTP workers and surrounding residents. In this study, air samples were collected from various treatment facilities of a typical WWTP. Community compositions of airborne bacteria were identified by high-throughput sequencing technique. Read More
Cognition 2018 Dec 3;183:269-276. Epub 2018 Dec 3.
Department of Linguistics, University of Hong Kong, Hong Kong.
This cross-modal priming study is one of the first to empirically test the long-held assumption that individual morphemes of multimorphemic words are represented according to a hierarchical structure. The results here support the psychological reality behind this assumption: Recognition of trimorphemic words (e.g. Read More
J Neurol Sci 2018 Nov 28;396:225-231. Epub 2018 Nov 28.
Department of Ophthalmology, Military General Hospital of Beijing PLA, Beijing, China. Electronic address:
Background And Objective: Adult demyelinating optic neuritis (ON) with positive myelin-oligodendrocyte glycoprotein antibody (MOG-Ab) has distinct clinical features. This study aimed to investigate the point prevalence, relationship with steroid dependency and prognosis value of MOG-Ab in adult ON.
Methods: Clinical data analysis was undertaken in adults with ON admitted between December 2014 and January 2016. Read More
Midwifery 2018 Nov 23;69:158-162. Epub 2018 Nov 23.
Nursing Department of Shanghai First Maternity and Infant Hospital, Tongji University School of Medicine, No.2699, West Gaoke Road, Pudong New Area, Shanghai 201204, China.
Background: Depression is the most prevalent psychiatric disease during and after pregnancy (Aktas and Yesilcicek, 2015). Social supportive system (SSS) serves to protect against the development of depressive symptoms (Moshki and Cheravi, 2016). The mitigating effect of SSS on depression among expectant Chinese women is unclear. Read More
Water Res 2018 Nov 21;150:191-199. Epub 2018 Nov 21.
Key Laboratory of Environmental Nanotechnology and Health Effects, Research Center for Eco-Environmental Sciences, Chinese Academy of Sciences, Beijing, 100085, PR China; Centre of Integrated Water-Energy-Food Studies (iWEF), School of Animal, Rural, and Environmental Sciences, Nottingham Trent University, Brackenhurst Campus, NG25 0QF, UK. Electronic address:
Many arsenic-bearing freshwaters are facing with eutrophication and consequent algae-induced anoxia/hypoxia events. However, arsenic cycling in eutrophic waters and its impact on public health are poorly understood. Laboratory simulation experiments are performed in this study to investigate the effect of algal blooms on the cycling of arsenic in a sediment-water-air system. Read More
Biomed Pharmacother 2018 Dec 3;110:302-311. Epub 2018 Dec 3.
College of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu 610075, PR China; Sichuan Neo-Green Pharmaceutical Technology Development Co., Ltd, Chengdu 610081, PR China. Electronic address:
Ethnopharmacological Relevance: Er Shen Wan (ESW), has been empirically used for treating spleen-kidney Yang deficiency (SKYD) syndrome in Traditional Chinese medicine (TCM) for centuries and shows a variety of activities. The medicinal formula is a mixture of two component herbs, Psoraleae Fructus (PF, Bu-Gu-Zhi in Chinese) and Myristicae Semen (MS, Rou-Dou-Kou in Chinese). The current study was designed to evaluate ESWP antidiuretic treatment of polyuria and to explore potential mechanisms of renal water metabolism in the rat model of SKYD-induced diarrhea. Read More
Atherosclerosis 2018 Nov 23;280:147-154. Epub 2018 Nov 23.
Department of Anesthesiology, Shuan Ho Hospital, Taipei Medical University, New Taipei City, Taiwan; Department of Anesthesiology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan; Department of Anesthesiology, Taipei Medical University Hospital, Taipei, Taiwan; Health Policy Research Center, Taipei Medical University Hospital, Taipei, Taiwan; School of Chinese Medicine, College of Chinese Medicine, China Medical University, Taichung, Taiwan. Electronic address:
Background And Aims: The risk of stroke in epileptic patients and the impact of epilepsy history on stroke patients' outcome have not been studied completely. Our purpose is to evaluate whether patients with epilepsy have increased risk of stroke or post-stroke mortality.
Methods: In Study I, we conducted a retrospective cohort study of 6746 patients with newly diagnosed epilepsy and 26,984 persons without epilepsy between 2000 and 2008, in the database of National Health Insurance in Taiwan. Read More
Bioelectrochemistry 2018 Aug 22;126:64-71. Epub 2018 Aug 22.
Key Laboratory of Marine Materials and Related Technologies, Zhejiang Key Laboratory of Marine Materials and Protective Technologies, Ningbo Institute of Materials Technology and Engineering, Chinese Academy of Sciences, Ningbo 315201, China.
The adverse corrosion and corrosion inhibitory effects of the marine isolated bacterium Bacillus vietnamensis were determined on different alloys. The corrosion rates of the steel alloys increased in the presence of Bacillu vietnamensis; although the alloys containing Cu were found to be protected from corrosion when exposed to this bacterium. The first assay bacterial mechanism confirmed the presence of protease enzyme, which was then identified by LC-MS/MS analysis. Read More
J Ethnopharmacol 2018 Dec 3. Epub 2018 Dec 3.
CSIR-National Botanical Research Institute, Plant Transgenic Laboratory, P.O. Box 436, Rana Pratap Marg,Lucknow-226 001, U.P., India. Electronic address:
Ethnopharmacological Relevance: The genus Psoralea (Fabaceae) harbours 105 accepted species that are extensively used by local peoples and medicinal practitioners of China, India, and other countries for treatment of tooth decay, psoriasis, leucoderma, leprosy, kidney problems, tuberculosis, indigestion, constipation and impotence. Presently, pharmacological research reports are available on only few species namely Bituminaria bituminosa (Syn: P. bituminosa), P. Read More
Int Immunopharmacol 2018 Dec 3;66:336-346. Epub 2018 Dec 3.
Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, 524001, China. Electronic address:
Acute lung injury (ALI), which is mainly triggered by infection, pneumonia, vasculitis, and sepsis, has no specific and effective therapy except for primary supportive treatment or bedside care. Excessive inflammation caused by innate immune cells is the major characteristic of ALI. Forsythoside B, a phenylethanoside compound, possesses good antioxidant and anti-bacterial properties in vivo and in vitro. Read More
Brain Res Bull 2018 Dec 3. Epub 2018 Dec 3.
Department of Encephalopathy, Shaanxi Provincial Hospital of Traditional Chinese Medicine, Xi'an, Shaanxi, 710003, China. Electronic address:
Reticulons (RTNs) are a group of membrane-bound proteins that are dominantly localized to the endoplasmic reticulum (ER). RTN1-C, one isoform of RTNs highly expressed in the brain, has been shown to mediate neuronal injury in cerebral ischemia models. The aim of this study was to investigate the role of RTN1-C in an in vitro model of Parkinson's disease (PD) mimicked by 1-Methyl-4-phenylpyridinium (MPP) treatment in SN4741 cells. Read More
Biochim Biophys Acta Mol Cell Biol Lipids 2018 Dec 3. Epub 2018 Dec 3.
State Key Laboratory of Molecular Developmental Biology, Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China; University of Chinese Academy of Sciences, Beijing 100049, China. Electronic address:
Lipid homeostasis is important for executing normal cellular functions and maintaining physiological conditions. The biophysical properties and intricate metabolic network of lipids underlie the coordinated regulation of different lipid species in lipid homeostasis. To reveal the homeostatic response among different lipids, we systematically knocked down 40 lipid metabolism genes in Drosophila S2 cells by RNAi and profiled the lipidomic changes. Read More
Int J Biol Macromol 2018 Dec 3. Epub 2018 Dec 3.
Key Laboratory of Traditional Chinese Veterinary Medicine and Animal Health in Fujian Province, Fujian Agriculture and Forestry University, Fuzhou 350002, PR China. Electronic address:
Codonopsis pilosula polysaccharides (CPPS) has been shown to possess a variety of biological activities. In previous study, CPPS was successfully modified to obtain its best selenizing Codonopsis pilosula polysaccharides (sCPPS). The purpose of this study was to investigate the protective effect of the selenizing derivative of CPPS (sCPPS) from HO-induced oxidative damage in RAW264. Read More
Life Sci 2018 Dec 3. Epub 2018 Dec 3.
College of Pharmacy, Nanjing University of Chinese Medicine, Nanjing 210023, China; Key Laboratory of Acupuncture and Medicine Research of Ministry of Education, Nanjing University of Chinese Medicine, Nanjing 210023, China. Electronic address:
Aims: Electro-acupuncture (EA) is frequently recommended as a complementary therapy for premature ovarian failure (POF) in the clinical. However, little information exists about its potential treatment mechanisms. The study was designed to observe the effect of EA to ovarian function and fertility in POF mice model, and investigated its potential mechanisms on PI3K/AKT/mTOR signaling pathway. Read More
J Theor Biol 2018 Dec 3. Epub 2018 Dec 3.
School of Electrical, Computer and Energy Engineering, Arizona State University, Tempe, AZ 85287, USA.; Department of Physics, Arizona State University, Tempe, Arizona 85287, USA.
Radiotherapy plays a vital role in cancer treatment, for which accurate prognosis is important for guiding sequential treatment and improving the curative effect for patients. An issue of great significance in radiotherapy is to assess tumor radiosensitivity for devising the optimal treatment strategy. Previous studies focused on gene expression in cells closely associated with radiosensitivity, but factors such as the response of a cancer patient to irradiation and the patient survival time are largely ignored. Read More
Fitoterapia 2018 Dec 3. Epub 2018 Dec 3.
Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, School of Medicine, Shenzhen University Health Science Center, Shenzhen 518060, People's Republic of China. Electronic address:
Nine multifarious new meroterpenoids, cochlearols E-M (1-9), along with seven known meroterpenoids 10-16, were isolated from the fruiting bodies of Ganoderma cochlear. Racemic 1, 6-8, 10 and 13 were separated by chiral HPLC. The structures were elucidated based on detailed spectroscopic analyses (HRESIMS, 1D/2D-NMR) and calculated electronic circular dichroism (ECD). Read More
Fitoterapia 2018 Dec 3. Epub 2018 Dec 3.
Guangdong Key Laboratory for Genome Stability & Disease Prevention, School of Pharmaceutical Sciences, Shenzhen University Health Science Center, Shenzhen 518060, PR China. Electronic address:
Two new nucleoside derivatives, named asponguanosines A and B (1 and 2), three new N-acetyldopamine analogues, aspongamides C-E (3-5), one new sesquiterpene, aspongnoid D (6), and three known compounds were isolated from the medicinal insect Aspongopus chinensis. Their structures including absolute configurations were assigned by using spectroscopic methods and ECD and C NMR calculations. Biological activities of compounds 3-7 towards human cancer cells, COX-2, ROCK1, and JAK3 were evaluated. Read More
J Invest Dermatol 2018 Dec 3. Epub 2018 Dec 3.
Department of Paediatrics, Prince of Wales Hospital, Hong Kong, SAR China.
Some previously described environmental associations for atopic eczema (AE) may be due to reverse causation. We explored the role of reverse causation by comparing individual- and school-level results for multiple AE risk factors. ISAAC Phase Three surveyed children within schools (the sampling unit) on AE symptoms and potential risk factors. Read More
Am J Obstet Gynecol 2018 Dec 3. Epub 2018 Dec 3.
Department of Dermatology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China. Electronic address:
Cochrane Database Syst Rev 2018 Dec 2;12:CD011215. Epub 2018 Dec 2.
School of Korean Medicine, Pusan National University, Beom-eu, Meulgeum, Yangsan, Korea, South, 626-870.
Background: Carpal tunnel syndrome (CTS) is a compressive neuropathic disorder at the level of the wrist. Acupuncture and other methods that stimulate acupuncture points, such as electroacupuncture, auricular acupuncture, laser acupuncture, moxibustion, and acupressure, are used in treating CTS. Acupuncture has been recommended as a potentially useful treatment for CTS, but its effectiveness remains uncertain. Read More
Br J Pharmacol 2018 Dec 6. Epub 2018 Dec 6.
Division of Hypothalamic Research, the University of Texas Southwestern Medical Center at Dallas, Dallas, Texas, USA.
Background And Purpose: Acute insulin administration results in a hyperpolarization and concomitant decrease of firing rate in a subpopulation of arcuate Proopiomelanocortin (POMC) and Neuropeptide Y/Agouti-related peptide (NPY/AgRP) cells. This rapid effect on cellular activity has been implicated as a cellular correlate of insulin effects on energy balance and glucose homeostasis. Recent evidence suggests that zinc in mammalian insulin formulations is required for the insulin-induced inhibition of arcuate POMC neurons, while guinea-pig insulin, which fails to bind zinc, activates POMC neurons in mice. Read More
PLoS One 2018 6;13(12):e0208690. Epub 2018 Dec 6.
CAS Key Laboratory of Mental Health, Institute of Psychology, Beijing, China.
Self-care is important for type 2 diabetes mellitus (T2DM) patients' disease prognosis, but there is a common phenomenon of self-regulation failure in T2DMs. In order to figure this problem out, the current study explored the interaction between self-regulation resource depletion and diabetes self-care based on the limited resource model of self-regulation. 104 patients were surveyed using the Self-Regulatory Fatigue Scale (SRF-S) and the Diabetes Self-care Scale (DSCS) in study 1. Read More
PLoS One 2018 6;13(12):e0208473. Epub 2018 Dec 6.
Department of Psychology, School of Sociology and Psychology, Central University of Finance and Economics, Beijing, China.
We were interested in how specific cultural value and adolescent social behavior would influence each other over time. Thus the present study explored the longitudinal and bidirectional relations between adolescents' power distance value and prosocial behavior toward powerful people over a year. A sample of 434 Chinese adolescents participated in the investigation (initial mean age = 11. Read More
PLoS One 2018 6;13(12):e0208398. Epub 2018 Dec 6.
Department of Neuroepidemiology, Beijing Neurosurgical Institute, Capital Medical University, Beijing, China.
Stroke is a serious threat to human health that often leads to severe complications, and currently ranks first as leading cause of death in China. However, reliable data on stroke burden in China in the 21st century are lacking. We used the data from NESS-China (National Epidemiological Survey of Stroke in China) for assessing the adverse health effects of stroke in Chinese population. Read More
PLoS One 2018 6;13(12):e0207392. Epub 2018 Dec 6.
Sanbo Brain Institute, Sanbo Brain Hospital, Capital Medical University, Beijing, China.
Background: Insomnia is one of the main symptoms of sleep disorders. Previous studies have suggested that alcohol intake is associated with several adverse health outcomes. The association between alcohol consumption and insomnia has been addressed in several studies with different results. Read More
PLoS One 2018 6;13(12):e0207683. Epub 2018 Dec 6.
Teaching Hospital, School of Clinical Medicine, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Atherosclerosis-predominant vasculopathy is a common complication of diabetes with high morbidity and high mortality, which is ruining the patient's daily life. As is known to all, traditional Chinese medicine (TCM) SHENQI compound and western medicine rosiglitazone play an important role in the treatment of diabetes. In particular, SHENQI compound has a significant inhibitory effect on vascular lesions. Read More
Endocr Connect 2018 Dec 1. Epub 2018 Dec 1.
L Chen, Endocrinology, Tongji Hospital affiliated with Tongji Medical School of Huazhong University of Science and Technology, Wuhan, 430022, China.
Screening for (pre)diabetes is recommended in China using fasting blood glucose as routine strategy currently but not oral glucose tolerance test (OGTT) in high-risk population. We aimed to explore the impact by not performing an OGTT in Han Chinese over 40 years. 6682 participants were included in the prospective cohort study followed up for 3 years. Read More
Expert Opin Pharmacother 2018 Dec 6:1-8. Epub 2018 Dec 6.
d Division of Cardiology, Department of Medicine and Therapeutics , The Chinese University of Hong Kong, Prince of Wales Hospital , Hong Kong , China.
Introduction: Direct oral anticoagulants (DOACs) have gained momentum in recent years in patients requiring anticoagulation for the prevention and management of venous thromboembolism and thromboembolic events caused by atrial fibrillation. The use of these agents involves potential bleeding complications, particularly during invasive procedures. With increasing use of DOACs, adequate knowledge regarding the perioperative management of patients on DOACs has become indispensable. Read More
FASEB J 2018 Dec 6:fj201802075R. Epub 2018 Dec 6.
Key Laboratory of Microgravity, Center of Biomechanics and Bioengineering, Institute of Mechanics, Chinese Academy of Sciences, Beijing, China.
Bone marrow-derived mesenchymal stem cells (BMSCs) are able to differentiate into functional hepatocytelike cells, which are expected to serve as a potential cell source in regenerative medicine, tissue engineering, and clinical treatment of liver injury. Little is known about whether and how space microgravity is able to direct the hepatogenic differentiation of BMSCs in the actual space microenvironment. In this study, we examined the effects of space microgravity on BMSC hepatogenic differentiation on board the SJ-10 Recoverable Scientific Satellite. Read More
ACS Chem Neurosci 2018 Dec 6. Epub 2018 Dec 6.
CAS Key Laboratory of Receptor Research , Shanghai Institute of Materia Medica, Chinese Academy of Sciences , 555 Zu Chong Zhi Road , Shanghai 201203 , China.
Alzheimer's disease (AD) is well-known as a severe neurodegeneration disease involving complicated etiologies, and cholinesterase inhibition remain the prevailing mode of clinical intervention in AD management. Although most clinically applied cholinesterase inhibitors (ChEIs) achieve limited clinical outcomes, research on the central cholinergic system is still thriving. Recently, an impressive amount of knowledge regarding novel acetylcholinesterase functions, as well as the close association between the central cholinergic system and other key elements for AD pathogenesis, has accumulated, highlighting that this field still has great potential for future drug development. Read More
Thorac Cancer 2018 Dec 6. Epub 2018 Dec 6.
Department of Interventional Medicine, The Second Hospital of Shandong University, Jinan, China.
Surgery remains the first choice of cure for early stage lung cancer. However, many patients are diagnosed at advanced stage, and thus miss the opportunity to undergo surgery. As such patients derive limited benefits from chemotherapy or radiotherapy, alternatives focusing on local control have emerged, including iodine-125 seed implantation. Read More
Depress Anxiety 2018 Dec 6. Epub 2018 Dec 6.
School of Biomedical Sciences, The Chinese University of Hong Kong, Shatin, Hong Kong.
Background: Numerous studies have suggested associations between depression and cardiometabolic (CM) diseases. However, little is known about the mechanism underlying this comorbidity, and whether the relationship differs by depression subtypes.
Methods: Using polygenic risk scores (PRS) and linkage disequilibrium (LD) score regression, we investigated the genetic overlap of various depression-related phenotypes with a comprehensive panel of 20 CM traits. Read More
Int J Cancer 2018 Dec 6. Epub 2018 Dec 6.
Sun Yat-sen University Cancer Center; State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Guangzhou 510060, China.
The prevalence of Lynch syndrome (LS) varies significantly in different populations, suggesting that ethnic features might play an important role. We enrolled 3330 consecutive Chinese patients who had surgical resection for newly diagnosed colorectal cancer. Universal screening for LS was implemented, including immunohistochemistry for mismatch repair (MMR) proteins, BRAF mutation test and germline sequencing. Read More
J Natl Cancer Inst 2018 Dec 6. Epub 2018 Dec 6.
Nanchang Center for Disease Control and Prevention, Nanchang, China.
Background: There is international consensus that benzene exposure is causally related to acute myeloid leukemia (AML), and more recent evidence of association with myelodysplastic syndromes (MDS). However, there are uncertainties about the exposure response, particularly risks by time since exposure and age at exposure.
Methods: In a case-cohort study in 110 631 Chinese workers followed up during 1972-1999 we evaluated combined MDS/AML (n = 44) and chronic myeloid leukemia (n = 18). Read More
Org Biomol Chem 2018 Dec 6. Epub 2018 Dec 6.
Department of Chemistry, Fudan University, Shanghai 200433, China.
The radical S-adenosylmethionine (SAM) superfamily is currently the largest known enzyme family. These enzymes reductively cleave SAM to produce a highly reactive 5'-deoxyadenosyl (dAdo) radical, which abstracts a hydrogen from the substrate and initiates diverse reactions. The canonic dAdo radical-mediated hydrogen abstraction can be changed to radical addition reactions by using olefin-containing substrate analogues, which result in adenosylation reactions. Read More
Org Biomol Chem 2018 Dec 6. Epub 2018 Dec 6.
Department of Chemistry, Huaibei Normal University, Huaibei, Anhui 235000, P. R. China. and State Key Laboratory of Organometallic Chemistry, Shanghai Institute of Organic Chemistry, Chinese Academy of Sciences, Shanghai 200032, P. R. China.
An effective protocol of photoredox catalyzed C2-alkylation of benzothiazoles with aliphatic carboxylic acids was disclosed. In the presence of an acridinium salt as a photocatalyst and air as an oxidant, a wide range of secondary or tertiary aliphatic carboxylic acids were employed as alkylation reagents, providing the desired products in good to excellent yields under mild reaction conditions with a broad substrate scope. Read More
Phys Chem Chem Phys 2018 Dec 6. Epub 2018 Dec 6.
College of Materials Science and Opto-electronic Technology, University of Chinese Academy of Sciences, Beijing 100049, P. R. China.
Layered P2-type CuO-coated Na2/3[Ni1/3Mn2/3]O2 (NNMO@CuO) with excellent rate capability and cycling performance was investigated as a sodium-ion battery cathode material for the first time. The NNMO@CuO cathode material combines the advantages of CuO coating and Cu2+ doping. Transmission electron microscopy (TEM) images, TEM elemental line scan analysis and ex situ scanning electron microscopy (SEM) images show that CuO has been successfully coated on the particle surface uniformly, and that this CuO layer effectively suppresses the exfoliation of the metal oxide layers and unfavorable side reactions. Read More
Aging Ment Health 2018 Dec 6:1-8. Epub 2018 Dec 6.
a Department of Social Work and Social Administration , The University of Hong Kong , Hong Kong.
Objectives: This study investigated the association between healthy lifestyle comprised of multiple domains, gender, and cognitive function in older Chinese people in Hong Kong.
Methods: We conducted a cross-sectional analysis with data from 1,831 community-dwellers aged 65 years and above. Participants' basic demographics, comorbidity, and six lifestyle factors: diet; smoking; alcohol drinking; and physical, mental, and social activities were surveyed. Read More
J Nat Prod 2018 Dec 6. Epub 2018 Dec 6.
Department of Natural Medicine Chemistry, School of Traditional Chinese Pharmacy , China Pharmaceutical University , 24 Tongjiaxiang , Nanjing 210009 , People's Republic of China.
Five oleanane-type triterpene glycosides including three new ones, proceraosides E-G (1-3), were isolated from a MeOH-soluble extract of Albizia procera bark. The structures of 1-3 were determined by use of NMR spectra, HRESIMS, and chemical methods. Compounds 1-5 exhibited inhibitory activities against the proliferation of the A549, SKBR3, AZ521, and HL60 human cancer cell lines (IC 0. Read More
Chem Res Toxicol 2018 Dec 6. Epub 2018 Dec 6.
Diosbulbin B (DBB) and 8-epidiosbulbin E acetate (EEA), belonging to furan-containing diterpenoid lactones, are the primary components of Dioscorea bulbifera L. (DB), a traditional Chinese medicine herb. Our earlier studies indicated that consumption of DBB or EEA induced acute hepatotoxicities. Read More
J Diabetes Investig 2018 Dec 6. Epub 2018 Dec 6.
Division of Endocrinology and Metabolism, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.
Diabetes remains a global epidemic problem and a tremendous health challenge especially in Asian population. Dramatic increases in the prevalence of diabetes across different countries or areas in Asia have been reported in recent epidemiological studies. While clinical guidelines have strengthen appropriate anti-hyperglycaemic medications and lifestyle modifications for optimal diabetes management, inadequate glycaemic control still occurs in many patients with an increased risk of developing microvascular and macrovascular complications. Read More
Transbound Emerg Dis 2018 Dec 6. Epub 2018 Dec 6.
MOE Joint International Research Laboratory of Animal Health and Food Safety, Engineering Laboratory of Animal Immunity of Jiangsu Province, College of Veterinary Medicine, Nanjing Agricultural University, Nanjing, China.
H3N2 CIV originated from avian species and emerged in dogs in Asia around 2005 where it became enzootic before reaching the USA in 2015. To investigate the key aspects of the evolution of H3N2 CIV regarding its emergence and adaptation in the canine host, we conducted an extensive analysis of all publicly available H3N2 CIV sequences spanning a 10-year period. We believe that H3N2 AIVs transferred to canines around 2002-2004. Read More
Cancer Sci 2018 Dec 6. Epub 2018 Dec 6.
Hepatobiliary Center, The First Affiliated Hospital of Nanjing Medical University, Key Laboratory of Liver Transplantation, Chinese Academy of Medical Sciences, Nanjing, China.
circular RNAs (circRNAs), a novel class of non-coding RNAs, have emerged as indispensable modulators in human malignancies. Aberrant cellular senescence is a phenotype observed in various cancers. The association of circRNAs with cellular senescence in tumor is still a virgin soil to be upturned. Read More
Respirology 2018 Dec 6. Epub 2018 Dec 6.
Tuberculosis and Chest Service, Centre for Health Protection, Department of Health, Hong Kong, China.
Transfusion 2018 Dec 6. Epub 2018 Dec 6.
Fetal Medicine Center, Department of Obstetrics and Gynecology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, 510000, China.
Background: Alloanti-M was once regarded as not clinically significant, with a few exceptions in extremely rare cases. However, an increasing number of cases of severe hemolytic disease of the fetus and newborn (HDFN), resulting in fetal hydrops and recurrent abortion caused by alloanti-M, have been reported mainly in the Asian population.
Study Design And Methods: Three pregnant Chinese women with a history of abnormal pregnancy with hydrops fetalis were encountered. Read More
Cochrane Database Syst Rev 2018 Dec 6;12:CD010284. Epub 2018 Dec 6.
Cochrane Singapore, Singapore Clinical Research Institute, Nanos Building #02-01, 31 Biopolis Way, Singapore, Singapore, 138669.
Background: Traditional Chinese herbal medicine (TCHM) is widely used for treating vascular dementia (VaD) in China. Recent studies of a number of TCHMs have demonstrated in vitro biological activity and therapeutic effects in animals, but the published clinical evidence has not been systematically appraised.
Objectives: To evaluate the efficacy and safety of TCHMs listed in either the Chinese Pharmacopoeia (CP) or the Chinese National Essential Drug List (NEDL) that are used to treat VaD. Read More
Anatol J Cardiol 2018 Dec 6. Epub 2018 Dec 6.
Department of Ultrasound Diagnosis, The Second Affiliated Hospital (Xinqiao Hospital) of Chinese People's Liberation Army Medical University; Chongqing-China.
Objective: To explore the clinical features and surgical treatment experience of primary cardiac valve tumor.
Methods: The present study retrospectively analyzed the clinical data of 11 patients with primary valvular tumors who underwent surgical treatment in our department from 1980 to 2016. Echocardiography of preoperative patients was indicated as a heart valve tumor. Read More