33,993 results match your criteria Chinese medical journal[Journal]


Prognostic value of free triiodothyronine in patients with dilated cardiomyopathy.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Section of Pacing and Electrophysiology, Division of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu 210029, China.

Background: The association between free triiodothyronine (FT3) and long-term prognosis in dilated cardiomyopathy (DCM) patients has not been evaluated. The purpose of this study was to determine whether the level of FT3 could provide prognostic value in patients with DCM.

Methods: Data of consecutive patients diagnosed with DCM were collected from October 2009 to December 2014. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000896DOI Listing

Trans-cranial Doppler predicts early neurologic deterioration in anterior circulation ischemic stroke after successful endovascular treatment.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Department of Neurology, Liangxiang Hospital of Beijing Fangshan District, Beijing 102246, China.

Background: Early neurologic deterioration (END) may occur in patients with anterior circulation ischemic stroke (ACIS) after receiving endovascular treatment (EVT). Hemodynamic insufficiency, re-occlusion, and post-re-canalization hyper-perfusion are likely to play a critical role in END. We hypothesized that hemodynamic changes can predict END in patients with ACIS post-successful EVT using trans-cranial Doppler (TCD). Read More

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http://dx.doi.org/10.1097/CM9.0000000000000881DOI Listing

Zinc finger and BTB domain-containing protein 46 is essential for survival and proliferation of acute myeloid leukemia cell line but dispensable for normal hematopoiesis.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Department of Hematology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing 400038, China.

Background: Zinc finger and BTB domain-containing protein 46 (Zbtb46) is a transcription factor identified in classical dendritic cells, and maintains dendritic cell quiescence in a steady state. Zbtb46 has been reported to be a negative indicator of acute myeloid leukemia (AML). We found that Zbtb46 was expressed at a relatively higher level in hematopoietic stem and progenitor cells (HSPCs) compared to mature cells, and higher in AML cells compared to normal bone marrow (BM) cells. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000878DOI Listing

A guide to human microbiome research: study design, sample collection, and bioinformatics analysis.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Institute of Genetics and Developmental Biology, Chinese Academy of Sciences, Beijing 100101, China.

The purpose of this review is to provide medical researchers, especially those without a bioinformatics background, with an easy-to-understand summary of the concepts and technologies used in microbiome research. First, we define primary concepts such as microbiota, microbiome, and metagenome. Then, we discuss study design schemes, the methods of sample size calculation, and the methods for improving the reliability of research. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000871DOI Listing

Small airway immunoglobulin A profile in emphysema-predominant chronic obstructive pulmonary disease.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Department of Respiratory Medicine, Shanxi Bethune Hospital Affiliated to Shanxi Medical University, Taiyuan, Shanxi 030032, China.

Background: Due to airway remodeling and emphysematous destruction in the lung, the two classical clinical phenotypes of chronic obstructive pulmonary disease (COPD) are emphysema and bronchiolitis. The present study was designed to investigate the levels of small airway immunoglobulin A (IgA) in COPD with "emphysema phenotype." The study also evaluated the associations between the small airway IgA levels and the severity of disease by the extent of emphysema versus airflow limitation. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000863DOI Listing

Assessment and management of low anterior resection syndrome after sphincter preserving surgery for rectal cancer.

Chin Med J (Engl) 2020 Jun 26. Epub 2020 Jun 26.

Division of Colorectal Surgery, Department of Surgery, Severance Hospital, Yonsei University College of Medicine, Seoul 03722, Korea.

Many patients develop a variety of bowel dysfunction after sphincter preserving surgeries (SPS) for rectal cancer. The bowel dysfunction usually manifests in the form of low anterior resection syndrome (LARS), which has a negative impact on the patients' quality of life. This study reviewed the LARS after SPS, its mechanism, risk factors, diagnosis, prevention, and treatment based on previously published studies. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000852DOI Listing

Relationship between quantitative magnetic resonance imaging and clinical symptoms in patients with knee osteoarthritis.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

Department of Orthopaedics, Peking University Third Hospital, Beijing 100191, China.

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http://dx.doi.org/10.1097/CM9.0000000000000879DOI Listing

Association of serum zinc-α2-glycoprotein with non-alcoholic fatty liver disease.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

Department of Endocrinology and Metabolism, The First Affiliated Hospital of University of South China, Hengyang, Hunan 421001, China.

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http://dx.doi.org/10.1097/CM9.0000000000000873DOI Listing

Clinical significance of nuchal translucency measurement in routine prenatal examination.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

Department of Prenatal Diagnostic Center, The International Peace Maternity & Child Health Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200030, China.

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http://dx.doi.org/10.1097/CM9.0000000000000895DOI Listing

Successful treatment of cutaneous mucormycosis disseminated from pulmonary mucormycosis with liposomal amphotericin B and posaconazole.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

Department of Dermatology, Peking University People's Hospital, Beijing 100044, China.

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http://dx.doi.org/10.1097/CM9.0000000000000891DOI Listing

Polycyclic aromatic hydrocarbon: environmental sources, associations with altered lung function and potential mechanisms.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

Department of Occupational & Environmental Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

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http://dx.doi.org/10.1097/CM9.0000000000000880DOI Listing

Health effects of air pollution: a Southern European perspective.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

National Research Council (NCR) Institute for Biomedical Research and Innovation (IRIB), 90146 Palermo, Italy.

Objective: To summarize the main updated evidence about the health effects of air pollution, with a special focus on Southern Europe.

Data Sources: Literature was obtained through PubMed Central and the official websites of European Agencies and Scientific Societies.

Study Selection: Recent shreds of evidence about the health effects of air pollution coming from international reports and original research were collected and described in this review. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000869DOI Listing

Climate change, air pollution, and allergic respiratory diseases: a call to action for health professionals.

Chin Med J (Engl) 2020 Jun 24. Epub 2020 Jun 24.

School of Public Health, Sun Yat-sen University, Guangzhou, Guangdong 510080, China.

Rising emissions of greenhouse gases in the atmosphere have warmed the planet substantially and are also accompanied by poor air quality. The increased prevalence of allergic airway disease worldwide can be partially attributed to those global environmental changes. Climate change and air pollution pose adverse impacts on respiratory allergies, and that the mechanisms are complex and interactive. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000861DOI Listing

[Level and trend of respiratory diseases mortality in China from 2002 to 2016].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1895-1900

Department of Clinical Epidemiology and Tobacco Dependence Treatment Research, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

To analyze the level and trend of respiratory disease mortality in China from 2002 to 2016. The standardized mortality rates were calculated based on the China health statistics yearbook (2003-2012) and China statistical yearbook of health and family planning (2013-2017) data released by the statistical information center of National health Commission of the People's Republic of China. Joinpoint model was used to calculate the standardized mortality rates (SMR), Annual percentage change (APC) and the average annual percentage change (AAPC) for standardized mortality rates. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20191108-02430DOI Listing

[The role of Wnt/β-catenin/TCF-4 pathway on biological behavior of renal cell carcinoma and its mechanism].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1890-1894

Department of Urology, Cancer Hospital, Chinese Academy of Medical Sciences, Beijing 100021, China.

To investigate the role of Wnt/β-catenin/TCF-4 pathway in renal cancer cells and to analyze its possible mechanism. β-catenin and TCF-4 were inhibited by siRNA in 786-O cells. The proliferation of transfected cells was detected by CCK8. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20191107-02418DOI Listing

[Lymphocyte activation gene 3 expression on T lymphocyte cell subsets in patients with myelodysplastic syndrome].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1886-1889

Hematology Department, Tianjin Medical University General Hospital, Tianjin 300052, China.

To investigate the expression of Lymphocyte activation gene 3 (LAG3) in myelodysplastic syndromes (MDS) patients. A total of 16 MDS patients newly diagnosed in Hematology Department of Tianjin Medical University were enrolled from January to November 2019. The healthy control (HC) group includes 16 cases of healthy adults. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20200217-00322DOI Listing

[Analysis of survival and prognosis of Siewert Ⅱ/Ⅲ esophagogastric junction adenocarcinoma patients with non-operative acute upper gastrointestinal hemorrhage].

Authors:
L Tian L Yu

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1881-1885

Department of Comprehensive Oncology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To analyze the clinical characteristics and risk factors of non-operative acute upper gastrointestinal hemorrhage in patients with adenocarcinoma of the esophagogastric junction. The clinical diagnosis and treatment data of patients with adenocarcinoma of esophagogastric junction with non-operative acute upper gastrointestinal hemorrhage admitted to Cancer Hospital of Chinese Academy of Medical Sciences from 2004 to 2018 were collected retrospectively, and the survival of patients was followed up by telephone. SPSS software was used for database establishment and analysis. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20200404-01082DOI Listing

[The application of medical alliance mode inexercise rehabilitation management of patients after percutaneous coronary interventioninchest paincenter].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1877-1880

Chest Pain Center, Yancheng Third People's Hospital, The Affiliated Yanchen Hospital of Southeast University, Yancheng 224000, China.

To explore the comprehensive effect of exercise-based cardia crehabilitation in patients managed with medical alliance who have undergone percutaneous coronary intervention (PCI) from Chest Pain Center. A total of 91 post PCI patients with coronary atherosclerotic heart disease were enrolled into the study. Fifty-four patients were in exercise rehabilitation group and 37 patients were in control group according to whether they were managed with medical alliance. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20200328-00985DOI Listing

[Application of Endo-GIA stapler in laparoscopic radicalcystectomy].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1872-1876

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To explore the application of Endo-GIA stapler in laparoscopic radical cystectomy, especially in the treatment of lateral bladder ligament, and to evaluate its clinical feasibility and practicability. A retrospective analysis of clinical data about 38 cases of laparoscopic radical cystectomy (LRC) treated in the Department of Urology, Chaoyang Hospital of Beijing and Cancer Hospital, Chinese Academy of Medical Sciences from July 2017 to June 2019 were conducted. The patients were divided into Endo-GIA stopler group(18 cases) and non-Endo-GIA stopler group (20 cases) according to whether Endo-GIA stapler were used. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20190925-02112DOI Listing

[Clinical analysis of mediastinal lymph node dissection through sternotomy approach in the treatment of papillary thyroid carcinoma with mediastinal lymph node metastasis].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1866-1871

Department of Thoracic Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To investigate the rule of mediastinal lymph node metastasis of papillary thyroid carcinoma and the application of therapeutic mediastinal lymph node dissection through the sternotomy approach in the treatment of mediastinal lymph node metastasis of papillary thyroid carcinoma. All cases of papillary thyroid carcinoma with mediastinal lymph node metastasis treated through sternotomy cooperated by thoracic surgeons and head and neck surgeons from January 2006 to January 2017 in Cancer Hospital of Chinese Academy of Medical Sciences were included in this study. The distribution, metastasis rate, metastasis degree, surgical method, surgical complications and postoperative survival of patients with mediastinal lymph node metastasis were retrospectively analyzed. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20200428-01353DOI Listing

[Clinical characteristics of patients with antisynthetase syndrome and interstitial pulmonary disease].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1861-1865

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital/Institute of Respiratory Medicine, Chinese Academy of Medical Sciences/National Clinical Research Center for Respiratory Diseases, Beijing 100029, China.

To provide reference for clinicians in diagnosis and treatment of antisynthetase syndrome with interstitial pulmonary disease (ASS-ILD) by analyzing the clinical features, imaging features and pulmonary function changes of ASS-ILD patients. A total of 92 patients with ASS-ILD diagnosed in the Respiratory Center of China-Japan Friendship Hospital from January 2015 to May 2018 were included, clinical manifestations, high-resolution computed tomography (HRCT), pulmonary function test, treatment and outcome were retrospectively analyzed. The average age of the 92 patients was (58. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20191120-02521DOI Listing

[Comparison of islet autoantigen-specific T cell response detected by direct enzyme-linked immunospot (ELISPOT) assay and accelerated co-cultured dendritic cells (acDCs) assay].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1856-1860

Department of Metabolism and Endocrinology, Key Laboratory of Diabetes Immunology, Ministry of Education, the Second Xiangya Hospital, Central South University, National Clinical Research Center for Metabolic Diseases, Changsha 410011, China.

To investigate the effect of enzyme-linked immunospot (ELISPOT) on accelerated co-cultured dendritic cells (acDCs) and direct detection of islet full-length antigen-specific T cell response in peripheral blood of patients with type 1 diabetes mellitus (T1DM). Sixteen patients with T1DM[9 males, 7 females, mean age(28.5±9. Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20191128-02591DOI Listing

[Clinical characteristics of testicular adrenal rest tumor and factors associated with its occurrence in 21-hydroxylase deficiency patients].

Zhonghua Yi Xue Za Zhi 2020 Jun;100(24):1850-1855

Department of Endocrinology, Peking Union Medical College Hospital, Key Laboratory of Endocrinology, National Health Commission, Beijing 100730, China.

To analyze the occurrence and clinical characteristics of testicular adrenal rest tumor (TART) in 21-hydroxylase deficiency (21-OHD) patients, and further explore the possible factors related to the occurrence of TART. Twenty-seven male 21-OHD patients who visited Peking Union Medical College Hospital from January to December 2018 were enrolled and their clinical and biochemical data were collected. The CYP21A2 mutations were identified by Sanger sequencing and multiple ligation probe amplification (MLPA). Read More

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http://dx.doi.org/10.3760/cma.j.cn112137-20191104-02389DOI Listing

Gut inflammation in the pathogenesis of acquired aplastic anemia.

Chin Med J (Engl) 2020 Jun 18. Epub 2020 Jun 18.

Department of Hematology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong 266000, China.

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http://dx.doi.org/10.1097/CM9.0000000000000772DOI Listing

Establishment of endometriotic models: the past and future.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

Endometriosis is a prevalent chronic disease that affects approximately 6% to 10% of reproductive-aged women. Although numerous researchers have endeavored to explore the etiology of endometriosis over a century, its etiology still remains an enigma. The exploration of pathophysiologic mechanism and novel therapy for endometriosis depends on ideal endometriotic models. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000885DOI Listing

Multislice spiral computed tomography imaging in evaluating hemophilic arthropathy.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Medical Imaging, People's Hospital of Zhengzhou University, Henan Provincial People's Hospital, Central China Fuwai Hospital, Zhengzhou, Henan 450003, China.

Background: Certain hemophilia patients are unable to cooperate with or afford magnetic resonance imaging (MRI) examinations. The purpose of our study was to explore the value of multislice spiral computed tomography (MSCT) in evaluating hemophilic arthropathy (HA).

Methods: Thirty-eight patients with 73 joints of HA were consecutively selected from January 2016 to May 2018 for this prospective study. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000876DOI Listing

Risk factors and possible mechanisms of saphenous vein graft failure after coronary artery bypass surgery.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Cardiovascular Surgery, Tianjin Chest Hospital, Tianjin 300222, China.

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http://dx.doi.org/10.1097/CM9.0000000000000872DOI Listing

Effect of temperature maintenance by forced-air warming blankets of different temperatures on changes in inflammatory factors in children undergoing congenital hip dislocation surgery.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Operation Room, Guangzhou Women and Children's Medical Center, Guangzhou Medical University, Guangzhou, Guangdong 510623, China.

Background: Hypothermia is associated with many adverse clinical outcomes in pediatric patients, and thus, it is important to find an effective and safe method for preventing peri-operative hypothermia and its associated adverse outcomes in pediatric patients. This study aimed to investigate the effect of forced-air warming blankets with different temperatures on changes in the transforming growth factor-β (TGF-β), tumor necrosis factor (TNF)-α, interleukin (IL)-1β, and IL-10 levels in children undergoing surgical treatment for developmental displacement of the hip (DDH).

Methods: The study included 123 children undergoing surgery for DDH under general anesthesia. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000846DOI Listing

More mutation accumulation in Neisseria gonorrhoeae (NG) with susceptibility than that in NG with decreased susceptibility to ceftriaxone.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Institute of Dermatology, Guangzhou Medical University, Guangzhou, Guangdong 510095, China.

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http://dx.doi.org/10.1097/CM9.0000000000000884DOI Listing

Global lung cancer mortality trends and lifestyle modifications: preliminary analysis.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

High School of Health Administration, First Moscow Medical Academy, Moscow 119991, Russia.

Background: According to the Independent High-level Commission on Non-communicable Diseases (NCD) of the World Health Organization (WHO), global reduction in lung cancer mortality has been achieved since the year 2000, although this effect is not sufficient to reach the 30% reduction of mortality from NCDs by the year 2030, as stipulated by the United Nations Sustainable Development Goal 3.4. The objective of this study was to analyze whether the lifestyle changes implemented by the WHO at country level could have an impact on mortality from this form of cancer. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000918DOI Listing

Global alliance against chronic respiratory diseases demonstration project: aerosol pollution and its seasonal peculiarities in primary schools of Vilnius.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Public Health, Institute of Health Sciences, and Department of Children's Diseases, Institute of Clinical Medicine, Vilnius University Faculty of Medicine, LT-03101 Vilnius, Lithuania.

Background: The growing public health concern caused by non-communicable diseases in urban surroundings cannot be solved by health care alone; therefore - a multidisciplinary approach is mandatory. This study aimed to evaluate the airborne aerosol pollution level in primary schools as possible factor influencing origin and course of the diseases in children.

Methods: Seasonal aerosol particle number concentration (PNC) and mass concentration (PMC) were studied in the randomly selected eleven primary schools in the Lithuanian capital, Vilnius, as model of a middle-size Eastern European city. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000913DOI Listing

Herpes simplex virus associated sepsis in an immunocompetent adult: the value of next-generation sequencing.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Medical Intensive Care Unit, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences, Beijing 100730, China.

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http://dx.doi.org/10.1097/CM9.0000000000000893DOI Listing

Global Alliance against Chronic Respiratory Diseases symposium on air pollution: overview and highlights.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Division of Pulmonary, Critical Care, Sleep, and Allergy, Department of Medicine M/C 719, University of Illinois at Chicago, 840 S. Wood St., Chicago, IL 60612, USA.

A 1-day symposium before the annual meeting of the Global Alliance against Chronic Respiratory Diseases, gathered authorities and researchers from around the world to discuss the impact of air pollution on human and planetary health. Air quality is a high priority for Global Alliance against Chronic Respiratory Diseases and China, the host country. This article presents a summary, commentary, and amplification of the 17 presentations. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000877DOI Listing

MicroRNA-145 suppresses uveal melanoma angiogenesis and growth by targeting neuroblastoma RAS viral oncogene homolog and vascular endothelial growth factor.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Ophthalmology and Visual Science Key Lab, Beijing Key Laboratory of Intraocular Tumor Diagnosis and Treatment, Capital Medical University, Beijing 100730, China.

Background: Uveal melanoma (UM) is the most common primary intraocular malignancy in adults. It has been demonstrated that microRNA-145 (miR-145) is correlated with the progression of various cancers by regulating the expression of multiple target genes, especially a number of genes that regulate angiogenesis and proliferation. However, the underlying mechanisms of miR-145 in tumor angiogenesis of UM are still not well illustrated. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000875DOI Listing
June 2020
1.016 Impact Factor

Risk factors for surgical-site infections after radical gastrectomy for gastric cancer: a study in China.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Pancreatic and Gastric Surgery, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

Background: About 10% of patients get a surgical-site infection (SSI) after radical gastrectomy for gastric cancer, but SSI remains controversial among surgeons. The aim of this study was to explore the risk factors for SSIs after radical gastrectomy in patients with gastric cancer to guide clinical therapies and reduce the incidence of SSI.

Methods: The study was a retrospective cohort study in patients who underwent radical gastrectomy for gastric cancer. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000860DOI Listing

Prognostic factors of pacing-induced cardiomyopathy.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Emergency and Critical Care Center, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

Background: The detrimental outcomes of right ventricular pacing on left ventricular electromechanical function ultimately result in heart failure, a phenomenon termed pacing-induced cardiomyopathy (PICM) in clinical research. This study aimed to validate prognostic factors that can be used to identify patients with higher susceptibility to progress to the stage of cardiomyopathy before pacemaker implantation.

Methods: This observational analysis enrolled 256 patients between January 2013 and June 2016, 23 (8. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000856DOI Listing

Entecavir add-on Peg-interferon therapy plays a positive role in reversing hepatic fibrosis in treatment-naïve chronic hepatitis B patients: a prospective and randomized controlled trial.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Department of Gastroenterology and Hepatology, Shanghai Public Health Clinical Center, Fudan University, Shanghai 201500, China.

Background: The efficacy of entecavir (ETV) add-on peg-interferon therapy compared with ETV monotherapy in treatment-naïve hepatitis B virus (HBV) patients remains controversial. We investigated whether adding peg-interferon to ongoing ETV treatment leads to a better curative effect or not.

Methods: All patients have been recruited between August 2013 and January 2015 from the Shanghai Public Health Clinical Center and Zhongshan Hospital (China). Read More

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http://dx.doi.org/10.1097/CM9.0000000000000857DOI Listing

Regression of liver fibrosis: evidence and challenges.

Chin Med J (Engl) 2020 Jun 19. Epub 2020 Jun 19.

Liver Research Center, Beijing Friendship Hospital, Capital Medical University, Beijing Key Laboratory of Translational Medicine on Liver Cirrhosis, National Clinical Research Center of Digestive Diseases, Beijing 100050, China.

It has been reported that liver fibrosis could be reversed after eliminating liver injuries. This article systematically summarizes the evidence of fibrosis regression based on histology, liver stiffness, and serum biomarkers, and discusses several clinically relevant challenges. Evidence from liver biopsy has been regarded as the gold standard in the assessment of fibrosis regression. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000835DOI Listing

Current therapies for patients with acute exacerbation of idiopathic pulmonary fibrosis.

Chin Med J (Engl) 2020 Jun;133(12):1470-1472

Department of Pulmonary and Critical Care Medicine, Center of Respiratory Medicine, China-Japan Friendship Hospital, Capital Medical University National Clinical Research Center for Respiratory Diseases.

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http://dx.doi.org/10.1097/CM9.0000000000000864DOI Listing

Assessment of circulating tumor DNA in cerebrospinal fluid by whole exome sequencing to detect genomic alterations of glioblastoma.

Chin Med J (Engl) 2020 Jun;133(12):1415-1421

Department of Neurosurgery/Neuro-Oncology, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, China.

Background: Cerebrospinal fluid (CSF) has been demonstrated as a better source of circulating tumor DNA (ctDNA) than plasma for brain tumors. However, it is unclear whether whole exome sequencing (WES) is qualified for detection of ctDNA in CSF. The aim of this study was to determine if assessment of ctDNA in CSF by WES is a feasible approach to detect genomic alterations of glioblastoma. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000843DOI Listing

Age-dependent changes of total and differential white blood cell counts in children.

Chin Med J (Engl) 2020 Jun 16. Epub 2020 Jun 16.

Beijing Key Laboratory for Pediatric Diseases of Otolaryngology, Head and Neck, Surgery, Beijing Children's Hospital, Capital Medical University, National Center for Children Health, Beijing 100045, China.

Background: Total and differential white blood cell counts are important for the diagnostic evaluation of suspected diseases. To facilitate the interpretation of total and differential white blood cell counts in pediatric patients, the present study investigated age-dependent changes in total and differential white blood cell counts in healthy reference children.

Methods: Data were obtained from the Pediatric Reference Intervals in China study (PRINCE), which aims to establish and verify pediatric reference intervals for Chinese children based on a nationwide multicenter cross-sectional study from January 2017 to December 2018. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000854DOI Listing

Clinical and histopathological analyses of anaplastic myeloma.

Chin Med J (Engl) 2020 Jun 16. Epub 2020 Jun 16.

Department of Hematology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, Jinan, Shandong 250021, China.

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http://dx.doi.org/10.1097/CM9.0000000000000902DOI Listing

Ipsilateral breast metastasis from lung adenocarcinoma harboring anaplastic lymphoma kinase or ROS1 rearrangement and significant response after targeted therapy: report of two cases.

Chin Med J (Engl) 2020 Jun 16. Epub 2020 Jun 16.

Department of Respiratory Disease, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang 310000, China.

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http://dx.doi.org/10.1097/CM9.0000000000000890DOI Listing

Interpretation of Chinese expert consensus on diagnosis and management of amniotic fluid embolism.

Chin Med J (Engl) 2020 Jun 16. Epub 2020 Jun 16.

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

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http://dx.doi.org/10.1097/CM9.0000000000000886DOI Listing

Potential impact of epidural labor analgesia on the outcomes of neonates and children.

Chin Med J (Engl) 2020 Jun 11. Epub 2020 Jun 11.

Department of Anesthesiology and Critical Care Medicine, Peking University First Hospital, Beijing 100034, China.

This review summarizes recent evidences regarding the potential influences of epidural labor analgesia (ELA) on the outcomes of neonates and children. Terms and relevant words including "ELA," "ELA and neonatal outcomes," "ELA and children's development," and "ELA and children's neurocognitive development" were used to search articles published in PubMed database up to October 2019.Original articles and reviews regarding potential influences of ELA on neonates and children were identified. Read More

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http://dx.doi.org/10.1097/CM9.0000000000000900DOI Listing

Extended culture of day 3 embryos improves live birth rate in in vitro fertilization-embryo transfer.

Chin Med J (Engl) 2020 Jun 11. Epub 2020 Jun 11.

Key Laboratory of Fertility Preservation and Maintenance, Ministry of Education, School of Basic Medical Sciences, Ningxia Medical University, Yinchuan, Ningxia 750004, China.

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http://dx.doi.org/10.1097/CM9.0000000000000901DOI Listing

Effect of inositol 1, 4, 5-trisphosphate receptor dependent Ca2+ release in atrial fibrillation.

Chin Med J (Engl) 2020 Jun 11. Epub 2020 Jun 11.

Department of Cardiovascular Medicine, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi 330006, China.

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http://dx.doi.org/10.1097/CM9.0000000000000898DOI Listing

Cortical encephalitis with overlapping anti-N-methyl-D-aspartate receptor and anti-myelin oligodendrocyte glycoprotein antibodies: report of two cases.

Chin Med J (Engl) 2020 Jun 11. Epub 2020 Jun 11.

Department of Neurology, Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai 200127, China.

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http://dx.doi.org/10.1097/CM9.0000000000000894DOI Listing