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Chin Med J (Engl) 2019 Apr 10. Epub 2019 Apr 10.

Guangdong Cardiovascular Institute, Guangdong General Hospital, Guangdong Academy of Medical Sciences, Guangzhou, Guangdong 510100, China.

Background: Mental stress-induced myocardial ischemia (MSIMI) is closely associated with adverse cardiac events in coronary artery disease (CAD) patients and we aimed to determine whether biomarkers and blood pressure could be potential predictors of MSIMI.

Methods: This study enrolled 82 patients with documented CAD between Jun. 01, 2017 and Nov. Read More

Chin Med J (Engl) 2019 Apr 10. Epub 2019 Apr 10.

Department of Urology, Tangdu Hospital, The Fourth Military Medical University, Xi'an, Shaanxi 710038, China.

Background: This study was designed to evaluate the clinical and radiographic outcomes of patients with nutcracker syndrome (NCS) who were treated with three-dimensional printing (3DP) extravascular titanium stents (EVTSs). The 3DP EVTS was expected to release the hypertension of the left renal vein (LRV) produced by its compression between the superior mesenteric artery (SMA) and the aorta without causing any complications.

Method: The pre-operative kidney model of each patient was printed out to enable surgical planning. Read More

Chin Med J (Engl) 2019 Apr 10. Epub 2019 Apr 10.

Department of Hematology, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, China.

Background: Diagnosis of heparin-induced thrombocytopenia (HIT) is challenging. This study aimed to compare the diagnostic performance of HIT expert probability (HEP) and 4Ts scores, and to evaluate the interobserver reliability for the 4Ts score in a clinical setting.

Methods: This prospective study included HIT-suspected patients between 2016 and 2018. Read More

Chin Med J (Engl) 2019 Apr 10. Epub 2019 Apr 10.

Department of General Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100730, China.

Chin Med J (Engl) 2019 Apr 10. Epub 2019 Apr 10.

Department of Pediatric Gastroenterology, King Saud Bin Abdulaziz University for Health Sciences, National Guard Health Affairs, Jeddah, Kingdom of Saudi Arabia.

Chin Med J (Engl) 2019 Apr 9. Epub 2019 Apr 9.

Department of Gynecologic Oncology, Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Beijing 100006, China.

Chin Med J (Engl) 2019 Apr 9. Epub 2019 Apr 9.

State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangzhou Institute of Respiratory Health, the First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong 510120, China.

Chin Med J (Engl) 2019 Apr 9. Epub 2019 Apr 9.

Department of Hands and Feet Microsurgery, The Second Affiliated Hospital of Dalian Medical University, Dalian, Liaoning 116023, China.

Chin Med J (Engl) 2019 Apr 9. Epub 2019 Apr 9.

Department of Emergency Medicine, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1111-1115

Department of Cardiovascular and Thoracic Surgery, Children's Heart Center, the Second Affiliated Hospital & Yuying Children's Hospital, Institute of Cardiovascular Development and Translational Medicine, Wenzhou Medical University, Wenzhou 325027, China.

To investigate the role and related mechanism of resolvin D1 (RvD1) in lung ischemia-reperfusion injury (LIRI) in rats. Forty male Sprague-Dawley rats, 7-8 weeks, weighing 220-280 g, were divided into 4 groups using a random number table method: sham operation group, lung ischemia reperfusion control group, normal saline group, and RvD1 group. The rat model of LIRI was produced by 45 min of occlusion of the left hilum of lungs followed by 150 min reperfusion. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1106-1110

Department of Urological Transplantation, Second Xiangya Hospital of Central South University, Changsha 410011, China.

To analyze the data of kidney transplantation with allografts from intracerebral hemorrhage donors of China donation after citizen's death (CDCD) and provide evidence to guide the clinical practice. The clinical data of CDCD donors (age ≥10 years)and corresponding kidney allograft recipients, which were done by Second Xiangya Hospital of Central South University during January 1 2013 to December 31 2017, were analyzed retrospectively. 327 CDCD cases were analyzed, the number and percentage of intracerebral hemorrhage donors were gradually increasing and the percentage reached to 39. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1101-1105

Department of Urology, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100021, China.

To optimize the surgical procedures of laparoscopic radical cystectomy and urinary diversion for the elderly patients with bladder cancer, generalize operating technique, summarize clinical experiences. From July 2004 to October 2016, laparoscopic radical cystectomy (LRC) and urinary diversion was performed in 68 elderly patients (≥75 years old) diagnosed with bladder cancer in urology department of Beijing Chaoyang Hospital, Capital Medical University, and the relevant clinical and follow-up data were retrospectively reviewed. All the patients were pathologically diagnosed and their perioperative data, postoperative pathological results, postoperative complications and follow-up outcomes were recorded and analyzed. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1095-1100

Department of Radiology, Children's Hospital, Nanjing Medical University, Nanjing 210008, China.

To investigate the changes of default mode network in subjects with obstructive sleep apnea (OSA) using functional connectivity (FC). Clinical data were collected from thirty-three subjects with OSA who went to the Zhongda Hospital, Southeast University, and twenty-nine normal controls were recruited from community from Jan 2016 to Jan 2018. The OSA group was divided into two subgroups according to apnea-hypopnea index (AHI) and the lowest oxygen saturation at night: 15 patients in the mild group and 18 in the moderate to severe group. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1090-1094

Center Office, Beijing Tuberculosis and Thoracic Tumor Research Institute; Beijing Chest Hospital, Capital Medical University; Clinical Center on Tuberculosis, China CDC, Beijing 101149, China.

To explore the effect of alcohol drinking on sputum culture conversion at the end of second month and outcome of smear-positive pulmonary tuberculosis (PTB) patients. Total 2 067 patients aged 18 years and above diagnosed and treated from 2008 to 2011 in 49 TB institutions from 8 provinces, antonomous regions and municipalities were enrolled, according to tuberculosis situation and regional distribution in China. Those patients were divided into three groups according to alcohol drinking, including never alcohol drinker group, ever-alcohol drinker group and current alcohol drinker group, respectively. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1086-1089

Department of Breast Surgery, Affiliated Cancer Hospital of Zhengzhou University (Henan Cancer Hospital), Zhengzhou 450008, China.

To explore the preoperative evaluation of sentinel lymph node (SLN) biopsy using contrast-enhanced ultrasonography (CEUS) in early breast cancer patients and the involved disturbing factors. Eighty-three female early breast cancer patients who underwent concurrent surgery in the Affiliated Cancer Hospital of Zhengzhou University between January 2017 and May 2018 were enrolled. CEUS was used to seek SLN and determine lymph node metastasis after signature of preoperative informed consent. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1081-1085

Department of General Surgery, Beijing Friendship Hospital, Capital University of Medical Science, Beijing 100050, China.

To study the effect of death decoy receptor 3 on the prognosis of breast cancer and the invasive function of breast cancer cells . Expression of DcR3 were assessed qualitatively by Q-PCR to analyze the correlation in 115 mammary tissue samples with a 10-year median follow-up. The expression of DcR3 was examined in MCF7 and MDA-MB-231 cell lines using immunocytochemical staining and RT-PCR. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1075-1080

The Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer; Key Laboratory of Cancer Prevention and Therapy, Tianjin; Tianjin's Clinical Research Center for Cancer, Tianjin 300060, China.

Breast cancer stem cells (BCSC) have been suggested to have clinical implications for cancer therapeutics because of their proposed role in chemo-resistance. The aim of this study was to investigate effects of BCSC on endocrine therapy response by regulating PI3K/Akt/mTOR signaling pathway. We evaluated the susceptibility of BCSC to NVP-BKM120 (BKM120), a new generation of PI3K-specific inhibitor, when used individually or in combination with letrozole in vivo. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1069-1074

Department of Cardiac Surgery, Hebei Chest Hospital, Shijiazhuang 050041, China.

To evaluate the mid-term outcomes of bilateral radial artery (BRA) grafts in coronary artery bypass grafting (CABG). All perioperative medical records and follow-up results of CABG with BRA grafts in multi-centers of China were analyzed retrospectively. A total of 211 patients (170 males and 41 females) underwent CABG grafting with BRA conduits between August 2013 and September 2018, with a mean age of (56. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1063-1068

Department of Cardiac Surgery, Peking University Third Hospital, Beijing 100191, China.

To summarize the early experience and clinical value of minimally invasive coronary surgery-total arterial coronary revascularization (MICS-TACR) through the left anterior small incision. Between May 2015 and June 2018, a total of 31 consecutive cases [21 males and 10 females, aged (63.2±9. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1058-1062

Department of Cardiovascular Surgery, Zhongshan Hospital, Fudan University, Shanghai Institute of Cardiovascular Disease, Shanghai 200032, China.

To compare the advantages and disadvantages of total arterial revascularization (TAR) and conventional off-pump coronary artery bypass (OPCAB) grafting in patients with left ventricular dysfunction (LVD). Between January 2008 and March 2015, 76 patients who were scheduled to undergo selective OPCAB were selected for cardiac surgery in Zhongshan Hospital, Fudan University. The left ventricular ejection fraction of enrolled patients was less than 35%. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1053-1057

Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University School of Medicine, Shanghai 200025, China.

To evaluate the long-term clinical outcomes of multiple arterial off-pump coronary artery bypass grafting (OPCAB) on left main coronary artery or multivessel disease. A total of 329 patients [303 males and 26 females, with a mean age of (55.1±9. Read More

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1048-1052

Department of Cardiac Surgery, Ruijin Hospital, Shanghai Jiaotong University, Shanghai 200025, China.

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1044-1047

Department of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu 610041, China.

Zhonghua Yi Xue Za Zhi 2019 Apr;99(14):1041-1043

Department of Cardiovascular Surgery, Mount Sinai Saint Luke's, New York 10025, NY, USA.

Chin Med J (Engl) 2019 Apr 3. Epub 2019 Apr 3.

Department of Critical Care Medicine, Ruijin Hospital, North, School of Medicine, Shanghai Jiao Tong University, Shanghai 200025, China.

Chin Med J (Engl) 2019 Apr 3. Epub 2019 Apr 3.

Department of Medical Oncology, Beijing Key Laboratory of Clinical Study on Anticancer Molecular Targeted Drugs, National Cancer Center/National Clinical Research Center for Cancer/Cancer Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing 100021, China.

Chin Med J (Engl) 2019 Apr 3. Epub 2019 Apr 3.

Department of Respiratory and Critical Care Medicine, The First Affiliated Hospital of Guangxi Medical University, Nanning, Guangxi 530021, China.

Chin Med J (Engl) 2019 Apr 3. Epub 2019 Apr 3.

Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Peking University, Beijing 100191, China.

Background: Chronic obstructive pulmonary disease (COPD) and obstructive sleep apnea syndrome (OSA) are highly prevalent respiratory conditions. Their coexistence is referred to as the overlap syndrome. They are bothrelated to pulmonary hypertension (PH) development. Read More

Chin Med J (Engl) 2019 Apr 3. Epub 2019 Apr 3.

Reproductive Center, Department of Gynecology and Obstetrics, Sun Yat-sen University, Guangzhou, Guangdong 510120, China.

Background: There is no absolute consensus for the best time for triggering. The aim of this study was to investigate the effect of different proportion of dominant follicles (PDF) on the human chorionic gonadotropin (HCG) day for the clinical outcomes in patients with polycystic ovary syndrome (PCOS) of different ovarian stimulation protocols.

Methods: A total of 371 cycles of the gonadotropin-releasing hormone (GnRH) agonist long protocol and 347 cycles of GnRH antagonist protocol from January, 2014 to December, 2016 were included in this retrospective study. Read More

Chin Med J (Engl) 2019 Apr 5. Epub 2019 Apr 5.

Department of Neurosurgery, Beijing Shijitan Hospital, Capital Medical University, Beijing 100038, China.

Chin Med J (Engl) 2019 Apr 5. Epub 2019 Apr 5.

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing 100034, China.

Background: Estradiol, as an important hormone in follicular development and endometrial receptivity, is closely related to clinical outcomes of fresh in vitro fertilization embryo transfer (IVF-ET) cycles. The aim of this retrospective study was to evaluate the association between elevated serum estradiol (E2) levels on the day of human chorionic gonadotrophin (hCG) administration and IVF-ET pregnancy and birth outcomes.

Methods: A total of 1771 infertile patients with their first fresh IVF-ET cycles were analyzed retrospectively between January 2011 and January 2016 in Peking University First Hospital. Read More

Chin Med J (Engl) 2019 Apr 5. Epub 2019 Apr 5.

Department of Anesthesiology, West China Second Hospital of Sichuan University, Key Laboratory of Birth Defects and Related Diseases of Women and Children, Sichuan University, Ministry of Education, Chengdu 610041, China.

Chin Med J (Engl) 2019 Apr;132(8):1007-1008

Department of Anesthesiology, Beijing Friendship Hospital, Capital Medical University, Beijing 100050, China.

Chin Med J (Engl) 2019 Apr;132(8):1005-1006

Department of Health and Leisure Management, Yuanpei University of Medical Technology, Hsinchu, Taiwan 30015, China.

Chin Med J (Engl) 2019 Apr;132(8):1003-1004

Department of Neurosurgery, Peking Union Medical College Hospital, Peking Union Medical College, Chinese Academy of Medical Sciences, Beijing 100730, China.

Chin Med J (Engl) 2019 Apr;132(8):1000-1002

Department of Otorhinolaryngology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan 450052, China.

Chin Med J (Engl) 2019 Apr;132(8):998-999

Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.

Chin Med J (Engl) 2019 Apr;132(8):997

Chin Med J (Engl) 2019 Apr;132(8):996-997

Department of Neurology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui 230001, China.

Chin Med J (Engl) 2019 Apr;132(8):994-995

Department of Endocrinology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430030, China.

Chin Med J (Engl) 2019 Apr;132(8):990-993

Translational Medical Center for Development and Disease, Institute of Pediatrics, Shanghai Key Laboratory of Birth Defect, Children's Hospital of Fudan University, Shanghai 201102, China.

Chin Med J (Engl) 2019 Apr;132(8):987-989

Department of Cardiothoracic Surgery, Children's Hospital of Chongqing Medical University, Ministry of Education Key Laboratory of Child Development and Disorders.

Chin Med J (Engl) 2019 Apr;132(8):984-986

Department of Endocrinology, Tianjin First Center Hospital, Tianjin 300192, China.

Chin Med J (Engl) 2019 Apr;132(8):980-983

Department of Pediatric Cardiology, Guangdong Cardiovascular Institute, Guangdong Academy of Medical Science/Guangdong Provincial People's Hospital, Guangzhou, Guangdong 510080, China.

Chin Med J (Engl) 2019 Apr;132(8):976-979

Department of Gynecology, The First Affiliated Hospital of Chongqing Medical University, Chongqing 400000, China.

Chin Med J (Engl) 2019 Apr;132(8):963-975

Department of Anesthesiology, The First Affiliated Hospital of Yangtze University, Jingzhou, Hubei 434000, China.

Objective: The endothelial glycocalyx (eGC) is a dynamic and multicomponent layer of macromolecules found at the surface of vascular endothelium, which is largely underappreciated. It has recently been recognized that eGC is a major regulator of endothelial function and may have therapeutic value in organ injuries. This study aimed to explore the role of the eGC in various pathologic and physiologic conditions, by reviewing the basic research findings pertaining to the detection of the eGC and its clinical significance. Read More

Chin Med J (Engl) 2019 Apr;132(8):957-962

Department of Cardiology, Tianjin Chest Hospital, Tianjin 300222, China.

Objective: Saphenous vein grafts disease (SVGD) is a common complication after coronary artery bypass graft (CABG) and normally treated by percutaneous coronary intervention (PCI). The most common complication after SVG-PCI is slow or no-reflow. It is known that the no-reflow phenomenon occurs in up to 15% of the SVG-PCI and is associated with high risk of major adverse cardiac events (MACEs) and mortality, therefore, it is important to investigate the factors that could predict the clinical outcome of PCI for risk stratification and guiding interventions. Read More

Chin Med J (Engl) 2019 Apr;132(8):948-956

Department of Biochemistry and Molecular Biology, Medical College of Nanchang University, Nanchang, Jiangxi 330006, China.

Background: Cervical cancer has the fourth highest incidence and mortality rate of all cancers in women worldwide; it seriously harms their physical and mental health. The aim of this study was to observe the roles and preliminary mechanism of Taurine (Tau)-induced apoptosis in cervical cancer cells.

Methods: Cells from the human cervical cancer cell line SiHa were transfected with the recombinant plasmid pEGFP-N1-MST1 (mammalian sterile 20-like kinase 1); then, the cell proliferation activity was analyzed by the MTT assay, cell apoptosis by flow cytometry, and the related protein levels by Western blotting. Read More

Chin Med J (Engl) 2019 Apr;132(8):943-947

Department of Orthopaedics, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

Background: To prevent risk of life-threatening stent thrombosis, all patients need to undergo dual antiplatelet therapy (DAPT) for at least 6 weeks to 12 months after stent implantation. If DAPT is continued during noncardiac surgery, there is a risk of severe bleeding at the surgical site. Our study was to assess the risk of bleeding in patients with continued DAPT during orthopedic surgery. Read More

Chin Med J (Engl) 2019 Apr;132(8):935-942

Department of Cardiovascular Surgery, General Hospital of People's Liberation Army, Beijing 100853, China.

Background: There are few reports of peri-operative application of intra-aortic balloon pumping (IABP) in patients with coronary artery disease (CAD) and different grades of left ventricular dysfunction. This study aimed to analyze the early outcomes of peri-operative application of IABP in coronary artery bypass grafting (CABG) among patients with CAD and left ventricular dysfunction, and to provide a clinical basis for the peri-operative use of IABP.

Methods: A retrospective analysis of 612 patients who received CABG in the General Hospital of People's Liberation Army between May 1995 and June 2014. Read More