1,748,248 results match your criteria China & World Economy[Journal]


Chemical Components and Antibacterial Activity of the Essential Oil of Six Pyrrosia Species.

Chem Biodivers 2020 Jul 11. Epub 2020 Jul 11.

Shandng Drug and Food Vocational College, School of Pharmacy, East Chuzhang Road, New City of Science and Technology, Weihai High-tech Industrial Development Zone, Weihai city, CHINA.

The present study was aimed at analyzing the chemical components of the essential oil from six Pyrrosia species by GC-MS and evaluate their in vitro antibacterial activities. Seventy volatile compounds were identified in the essential oil of six Pyrrosia samples. The identified volatile components were divided into the following nine categories: aldehydes, terpenoids, fatty acids, ketone, furans, hydrocarbons, alcohols, esters, and phenols. Read More

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http://dx.doi.org/10.1002/cbdv.202000526DOI Listing

Two novel mutations in the MCM8 gene shared by two Chinese siblings with primary ovarian insufficiency and short stature.

Mol Genet Genomic Med 2020 Jul 11:e1396. Epub 2020 Jul 11.

Department of Endocrinology, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.

Background: Minichromosome maintenance complex component 8 (MCM8) is responsible for homologous recombination and DNA double-strand breaks (DSBs) repair and is the cause of primary ovarian insufficiency (POI), which is seldom diagnosed in adolescents and children.

Methods: Whole-exome sequencing was performed in a 13-year-old girl, and Sanger sequencing was used to identify potentially pathogenic variants in her sister (aged 6 years and 7 months) and parents. To identify potential pathogenic mutations, DSBs were induced by mitomycin C (MMC), and the DNA repair capacity was evaluated by the histone H2AX phosphorylation level. Read More

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http://dx.doi.org/10.1002/mgg3.1396DOI Listing

Improving timely treatment with a stroke emergency map: The case of northern China.

Brain Behav 2020 Jul 11:e01743. Epub 2020 Jul 11.

Department of Neurology, Taiyuan Central Hospital of Shanxi Medical University, Taiyuan, China.

Objective: The Chinese stroke emergency map (SEM) was implemented in 2017 to reduce prehospital and hospital delays for acute ischemic stroke (AIS) patients suitable for intravenous recombinant tissue plasminogen activator (rt-PA) thrombolysis. However, data on the time delay following the implementation of an SEM in China are limited.

Methods: Data for suspected stroke patients from the SEM registry center of Taiyuan, Shanxi Province, from August 2017 to July 2019, patients' characteristics, thrombolysis rate, and functional outcome at 90 days were analyzed. Read More

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http://dx.doi.org/10.1002/brb3.1743DOI Listing

The role of mab-3 in spermatogenesis and ontogenesis of pinewood nematode, Bursaphelenchus xylophilus.

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory of Subtropical Silviculture, College of Forestry and Biotechnology, Zhejiang Agricultural & Forestry University, Hangzhou, 311300, China.

Background: Bursaphelenchus xylophilus is one of the most destructive invasive species, causing extensive economic losses worldwide. The sex ratio of female to male of B. xylophilus plays an important role in the nematode infestation. Read More

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http://dx.doi.org/10.1002/ps.6001DOI Listing

Anxiety and Depression of Nurses in a North West Province in China During the Period of Novel Coronavirus Pneumonia Outbreak.

J Nurs Scholarsh 2020 Jul 11. Epub 2020 Jul 11.

Evidence-Based Nursing Center, School of Nursing, Lanzhou University, Lanzhou, Gansu, China.

Purpose: To investigate the anxiety and depression levels of frontline clinical nurses working in 14 hospitals in Gansu Province, China, during this period.

Design: A cross-sectional survey was conducted online between February 7 and 10, 2020, with a convenience sample of 22,034 nurses working in 14 prefecture and city hospitals in Gansu Province, located in northwest China.

Methods: A self-reported questionnaire with four parts (demographic characteristics, general questions related to novel coronavirus-infected pneumonia, self-rating anxiety scale, and self-rating depression scale) was administered. Read More

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http://dx.doi.org/10.1111/jnu.12590DOI Listing

Induced CO2 Electroreduction to Formic Acid on Metal-Organic Frameworks via Node Doping.

ChemSusChem 2020 Jul 11. Epub 2020 Jul 11.

Shanghai Advanced Research Institute, CAS Key Laboratory of Low-Carbon Vonversion Science and Engineering, 100 Haike Road, 201210, Shanghai, CHINA.

Metal-organic frameworks (MOFs), combining the advantages of heterogeneous and homogeneous components, have been explored as a novel kind of catalytic materials for CO 2 electroreduction reaction (CO 2 ERR). However, the unmatched metal nodes subject MOFs to the lower faradaic efficiency (FE) and limited current density in CO 2 ERR. Herein, we report a general strategy to promote activities of MOFs via node doping in CO 2 ERR. Read More

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http://dx.doi.org/10.1002/cssc.202001310DOI Listing

Protective effect of Lactobacillus salivarius Li01 on thioacetamide-induced acute liver injury and hyperammonaemia.

Microb Biotechnol 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory for Diagnosis and Treatment of Infectious Diseases, National Clinical Research Center for Infectious Diseases, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003, China.

The gut microbiota plays pivotal roles in liver disease onset and progression. The protective effects of Lactobacillus salivarius Li01 on liver diseases have been reported. In this study, we aimed to detect the protective effect of L. Read More

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http://dx.doi.org/10.1111/1751-7915.13629DOI Listing

A natural BACE1 and GSK3β dual inhibitor Notopterol effectively ameliorates the cognitive deficits in APP/PS1 Alzheimer's mice by attenuating amyloid-β and tau pathology.

Clin Transl Med 2020 Jul 11. Epub 2020 Jul 11.

Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang, People's Republic of China.

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http://dx.doi.org/10.1002/ctm2.50DOI Listing

LINC00160 mediated paclitaxel-And doxorubicin-resistance in breast cancer cells by regulating TFF3 via transcription factor C/EBPβ.

J Cell Mol Med 2020 Jul 11. Epub 2020 Jul 11.

Center for Precision Medicine, Anhui No.2 Provincial People's Hospital, Hefei, China.

Chemoresistance represents a major challenge in breast cancer (BC) treatment. This study aimed to probe the roles of LINC00160 in paclitaxel- and doxorubicin-resistant BC cells. Three pairs of BC and adjacent normal tissue were used for lncRNA microarray analysis. Read More

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http://dx.doi.org/10.1111/jcmm.15487DOI Listing

Knockdown of DNA binding protein A (dbpA) enhances the chemotherapy sensitivity of colorectal cancer via suppressing the Wnt/β-catenin/Chk1 pathway.

Cell Biol Int 2020 Jul 11. Epub 2020 Jul 11.

Department of hepatobiliary surgery, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, 710061, P.R. China.

DNA-binding protein A (dbpA) is reported to be upregulated in many cancers and associated with tumor progress. The present study aimed to investigate the role of dbpA in 5-Fluorouracil (5-FU)-resistant and Oxaliplatin (L-OHP)-resistant colorectal cancer (CRC) cells. We found that 5-FU and L-OPH treatment promoted the expression of dbpA. Read More

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http://dx.doi.org/10.1002/cbin.11416DOI Listing

Characterization of flupyradifurone resistance in the whitefly Bemisia tabaci Mediterranean (Q biotype).

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

Institute of Plant and Environment Protection, Beijing Academy of Agriculture and Forestry Sciences, Beijing, 100097, China.

Background: Bemisia tabaci is one of most notorious pests on various crops worldwide and many populations showed high resistance to different types of insecticides. Flupyradifurone is one novel insecticide against sucking pests. B. Read More

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http://dx.doi.org/10.1002/ps.5995DOI Listing

SNPs in SNCA, MCCC1, DLG2, GBF1 and MBNL2 are associated with Parkinson's disease in southern Chinese population.

J Cell Mol Med 2020 Jul 11. Epub 2020 Jul 11.

Department of Neurology and Institute of Neurology, Ruijin Hospital Affiliated with the Shanghai Jiaotong University School of Medicine, Shanghai, China.

Numerous single nucleotide polymorphisms (SNPs), which have been identified as susceptibility factors for Parkinson's disease (PD) as per genome-wide association studies, have not been fully characterized for PD patients in China. This study aimed to replicate the relationship between 12 novel SNPs of 12 genes and PD risk in southern Chinese population. Twelve SNPs of 12 genes were detected in 231 PD patients and 249 controls, using the SNaPshot technique. Read More

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http://dx.doi.org/10.1111/jcmm.15508DOI Listing

Acylglycerol kinase promotes the stemness of nasopharyngeal carcinoma cells by promoting β-catenin translocation to the nucleus through activating PI3K/Akt pathway.

Environ Toxicol 2020 Jul 11. Epub 2020 Jul 11.

Department of Otolaryngology, The First Affiliated Hospital of Soochow University, Suzhou City, Jiangsu Province, China.

Recent evidences show that acylglycerol kinase (AGK) expression is related to the occurrence and development of various human cancers. However, its roles in nasopharyngeal carcinoma (NPC) progression are still unclear. This work aims to explore the roles of AGK in NPC cell stemness. Read More

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http://dx.doi.org/10.1002/tox.22994DOI Listing

Priming of microglia with IFN-γ impairs adult hippocampal neurogenesis and leads to depression-like behaviors and cognitive defects.

Glia 2020 Jul 11. Epub 2020 Jul 11.

School of Life Science and Technology, Center for Informational Biology, University of Electronic Science and Technology of China, Chengdu, China.

Neuroinflammation driven by interferon-gamma (IFN-γ) and microglial activation has been linked to neurological disease. However, the effects of IFN-γ-activated microglia on hippocampal neurogenesis and behavior are unclear. In the present study, IFN-γ was administered to mice via intracerebroventricular injection. Read More

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http://dx.doi.org/10.1002/glia.23878DOI Listing

Administration of secretome from human placental stem cell conditioned media improves recovery of erectile function in the pelvic neurovascular injury model.

J Tissue Eng Regen Med 2020 Jul 11. Epub 2020 Jul 11.

Wake Forest Institute for Regenerative Medicine, Winston-Salem, NC, USA.

Introduction: Human placental stem cells (PSC) enhance histological and functional recovery in a rodent erectile dysfunction (ED) model. We tested the hypothesis that bioactive factors secreted by PSC (i.e. Read More

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http://dx.doi.org/10.1002/term.3105DOI Listing

Coupling Wireless Bipolar Ultramicroelectrode with Nano-electrospray Ionization Mass Spectrometry: Insights into the Ultrafast Initial Step of Electrochemical Reactions.

Angew Chem Int Ed Engl 2020 Jul 11. Epub 2020 Jul 11.

Najing University, Chemistry, Xianlin Ave. 163, , 210023, Nanjing, CHINA.

We report a new mass spectrometric method for detecting electrogenerated intermediates. This approach is based on simultaneous activation of electrospray ionization and redox reaction on a wireless bipolar ultramicroelectrode, which is fabricated in the tip of a quartz nanopipette. The hollow structure of the ultramicroelectrode permits rapid transferring the transient species from electrode-electrolyte interfaces into gas phase for mass spectrometric identification on the time scale of microseconds. Read More

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http://dx.doi.org/10.1002/anie.202008577DOI Listing

Sotrastaurin, a PKC inhibitor, attenuates RANKL-induced bone resorption and attenuates osteochondral pathologies associated with the development of OA.

J Cell Mol Med 2020 Jul 11. Epub 2020 Jul 11.

Department of Orthopedics, The Ninth Affiliated Hospital of Guangxi Medical University, Beihai, China.

Osteoarthritis (OA) is a common degenerative disease that affects the musculoskeletal structure of the whole joint, which is characterized by progressive destruction of both articular cartilage and subchondral bone. Treatment of the bone pathologies, particularly osteoclast-mediated subchondral bone loss in the early stages of OA, could prevent subsequent cartilage degeneration and progression of OA. In the present study, the PKC inhibitor, Sotrastaurin, was found to inhibit RANKL-induced osteoclast formation in vitro in a dose- and time-dependent manner. Read More

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http://dx.doi.org/10.1111/jcmm.15404DOI Listing

Loss of frontal regulator of vigilance during sleep inertia: A simultaneous EEG-fMRI study.

Hum Brain Mapp 2020 Jul 11. Epub 2020 Jul 11.

Sleep and NeuroImaging Center, Faculty of Psychology, Southwest University, Chongqing, China.

Sleep inertia refers to a distinct physiological state of waking up from sleep accompanied by performance impairments and sleepiness. The neural substrates of sleep inertia are unknown, but growing evidence suggests that this inertia state maintains certain sleep features. To investigate the neurophysiological mechanisms of sleep inertia, a comparison of pre-sleep and post-sleep wakefulness with eyes-open resting-state was performed using simultaneous EEG-fMRI, which has the potential to reveal the dynamic details of neuroelectric and hemodynamic responses with high temporal resolution. Read More

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http://dx.doi.org/10.1002/hbm.25125DOI Listing

The response of soil respiration to precipitation change is asymmetric and differs between grasslands and forests.

Glob Chang Biol 2020 Jul 11. Epub 2020 Jul 11.

Key Laboratory of Vegetation Restoration and Management of Degraded Ecosystems, South China Botanical Garden, Chinese Academy of Sciences, Guangzhou, China.

Intensification of the Earth's hydrological cycle amplifies the interannual variability of precipitation, which will significantly impact on terrestrial carbon (C) cycle. However, it is still unknown whether previously observed relationship between soil respiration (R ) and precipitation remains applicable under extreme precipitation change. By analyzing the observations from a much larger dataset of field experiments (248 published papers including 151 grassland studies and 97 forest studies) across a wider range of precipitation-manipulation than previous studies, we found that the R response to precipitation change was highly nonlinear or asymmetric, and differed significantly between grasslands and forests, between moderate and extreme precipitation changes. Read More

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http://dx.doi.org/10.1111/gcb.15270DOI Listing

Thymopentin improves the survival of septic mice by promoting the production of 15-deoxy-prostaglandin J2 and activating the PPARγ signaling pathway.

FASEB J 2020 Jul 11. Epub 2020 Jul 11.

Center for New Drug Safety Evaluation and Research, State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing, China.

Sepsis, a systemic inflammatory response syndrome (SIRS) caused by infection, is a major public health concern with limited therapeutic options. Infection disturbs the homeostasis of host, resulting in excessive inflammation and immune suppression. This has prompted the clinical use of immunomodulators to balance host response as an alternative therapeutic strategy. Read More

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http://dx.doi.org/10.1096/fj.202000467RDOI Listing

Letter to the Editor: D-dimer and presumptive diagnosis of COVID-19.

Acad Emerg Med 2020 Jul 11. Epub 2020 Jul 11.

Royal College Emergency Residency Program and Emergency Department, Faculty of Medicine, McGill University, Montréal, Canada.

We read with interest, "D-dimer triage for COVID-19" by Chenghong et al. This observational cohort study from Wuhan, China concludes that a D-dimer done at admission could be an effective and easily available diagnostic surrogate marker for coronavirus disease-19 (COVID-19). We are concerned that several limitations in the study's methodology affect the authors' conclusions. Read More

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http://dx.doi.org/10.1111/acem.14085DOI Listing

Tuning Electrical- and Photo-Conductivity by Cation Exchange within a Redox-Active Tetrathiafulvalene-Based Metal-Organic Framework.

Angew Chem Int Ed Engl 2020 Jul 11. Epub 2020 Jul 11.

Nanjing University, School of Chemistry and Chemical Engineering, Han Kou Road 22, 210093, Nanjing, CHINA.

To activate electronic and optical functions of the redox-active metal-organic framework, (Me 2 NH 2 )[In III (TTFTB)]·0.7C 2 H 5 OH· DMF (Me 2 NH 2 @ 1, TTFTB = tetrathiafulvalene-tetrabenzoate, DMF = N,N -dimethylformamide), has been exchanged by tetrathiafulvalenium (TTF •+ ) and N,N ' -dimethyl- 4,4 ' -bipyridinium (MV 2+ ). These cations provide electron carriers and photosensitivity. Read More

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http://dx.doi.org/10.1002/anie.202008941DOI Listing

STIs and the COVID-19 pandemic: the lockdown does not stop sexual infections.

J Eur Acad Dermatol Venereol 2020 Jul 11. Epub 2020 Jul 11.

Division of Dermatology, STI Clinic, Santa Chiara Hospital, Trento, Italy.

In December 2019 a novel coronavirus (SARS-CoV-2) emerged in Wuhan, China, responsible for an aggressive interstitial pneumonia. Italy was the first western country to be hit by the CoronaVIrus Disease 2019 (COVID-19) and on 9 March our Prime Minister announced a nationwide lockdown, strictly forbidding any contacts outside cohabitants, except for urgent or medical reasons. In compliance with the ministerial decree, all scheduled visits were suspended, maintaining hospital access only for emergencies. Read More

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http://dx.doi.org/10.1111/jdv.16808DOI Listing

Low-magnitude vibration induces osteogenic differentiation of bone marrow mesenchymal stem cells via miR-378a-3p/Grb2 pathway to promote bone formation in a rat model of age-related bone loss.

FASEB J 2020 Jul 11. Epub 2020 Jul 11.

Institute of Biomedical Engineering, West China School of Basic Medical Sciences and Forensic Medicine, Sichuan University, Chengdu, China.

The dysfunction of bone marrow mesenchymal stem cells (BMSCs) in osteogenic differentiation is one of the main causes of age-related bone loss. Our previous studies have shown that low-magnitude vibration (LMV) induces the osteogenic differentiation of BMSCs derived from ovariectomized osteoporotic rats. To investigate whether LMV promotes osteogenic differentiation of BMSCs and its underlying mechanisms in aged rats, 20-month-old female Sprague-Dawley rats (n = 20) were randomly divided into LMV group (rats were vibrated at 0. Read More

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http://dx.doi.org/10.1096/fj.201902830RRRDOI Listing

Density-induced social stress alters oxytocin and vasopressin activities in the brain of a small rodent species.

Integr Zool 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory of Integrated Pest Management, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.

It is known that social stress could alter oxytocin (OT) and arginine-vasopressin (AVP) expression in specific regions of brains which regulate the aggressive behavior of small rodents, but the effects of density-induced social stress are still unknown. Brandt's voles (Lasiopodomys brandtii) is a small herbivores in the grassland of China, but the underlying neurological mechanism of population regulation is still unknown. We tested the effects of housing density of Brandt's voles on OT/AVP system with physical contact (allowing aggression) and without physical contact (not allowing aggression) under laboratory conditionunder laboratory conditions. Read More

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http://dx.doi.org/10.1111/1749-4877.12467DOI Listing

The value of preoperative high-resolution MRI with microscopy coil for facial nonmelanoma skin cancers.

Skin Res Technol 2020 Jul 11. Epub 2020 Jul 11.

Department of Radiology, the First Affiliated Hospital of Soochow University, Suzhou, Jiangsu Province, P.R.China.

Background: The extent and depth of facial nonmelanoma skin cancers and the involvement of adjacent structures are critical features for surgical planning, but they are difficult to assess clinically. High-resolution MRI (HR-MRI) with microscopy coil may facilitate detailed evaluation of skin lesions. The authors performed this prospective study to determine the value of high-resolution microscopy coil MRI in the preoperative evaluation of nonmelanoma skin cancer. Read More

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http://dx.doi.org/10.1111/srt.12909DOI Listing

Identification and genetic characterization of Contracaecum sp. (Nematoda Anisakidae) from China.

Integr Zool 2020 Jul 11. Epub 2020 Jul 11.

National Research Center for Wildlife-Borne Diseases, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.

Contracaecum species are economically important fish-borne larval nematodes with zoonotic significance. In June 2019, more than one hundred piscivorous birds were died in its habitats close to the Wild Duck Lake, located in Yanqing, northwest of Beijing, China. Post-mortem examination of Black Night Herons (Nycticorax) revealed the presence of numerous anisakid nematodes in the proventriculus. Read More

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http://dx.doi.org/10.1111/1749-4877.12465DOI Listing

MIB1-mediated degradation of WRN promotes cellular senescence in response to camptothecin treatment.

FASEB J 2020 Jul 11. Epub 2020 Jul 11.

Department of Medical Genetics, Center for Medical Genetics, Peking University Health Science Center, Beijing, China.

Werner syndrome protein (WRN) plays critical roles in DNA replication, recombination, and repair, as well as transcription and cellular senescence. Ubiquitination and degradation of WRN have been reported, however, the E3 ubiquitin ligase of WRN is little known. Here, we identify mindbomb E3 ubiquitin protein ligase 1 (MIB1) as a novel E3 ubiquitin ligase for WRN protein. Read More

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http://dx.doi.org/10.1096/fj.202000268RRRDOI Listing

Tuning the adsorption selectivity of ZIF-8 by amorphization.

Chemistry 2020 Jul 11. Epub 2020 Jul 11.

Ningbo University, The School of Materials Science and Chemical Engineering, Fenghua Road 818#, 315211, Ningbo, CHINA.

Amorphous metal-organic frameworks (amMOFs) with partial collapsed structure present a new category of porous hybrid materials. Herein, a solid-state amorphization of ZIF-8 was achieved by mechanical compression at 0.75 GPa. Read More

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http://dx.doi.org/10.1002/chem.202001249DOI Listing

Explore quinclorac resistance mechanisms in Echinochloa crus-pavonis from China.

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

Australian Herbicide Resistance Initiative, School of Agriculture and Environment, University of Western Australia, Crawley, Australia.

Background: Barnyardgrass (Echinochloa spp.) is a global weed in rice fields. Quinclorac is commonly used to control barnyardgrass. Read More

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http://dx.doi.org/10.1002/ps.6007DOI Listing

Protective efficacy of phenoxyacetyl oxazolidine derivatives as safeners against nicosulfuron toxicity in maize.

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

Department of Applied Chemistry, College of Arts and Sciences, Northeast Agricultural University, Harbin, 150030, China.

Background: Herbicide safeners mitigate crop damage without reducing herbicide efficacy. Here, the protective effects of phenoxyacetyl oxazolidine derivatives as potential safeners were evaluated with a view toward reducing injury caused by sulfonylurea herbicide nicosulfuron to sensitive maize varieties.

Results: Growth indices demonstrated that the bioactivity of compound 9 (N-phenoxyacety-2-methyl-2,4-diethyl-1,3-oxazolidine) was superior to that of R-28725 and all other compounds tested. Read More

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http://dx.doi.org/10.1002/ps.6005DOI Listing

Phylogenetic analysis and expression differences of eye-related genes in cavefish genus Sinocyclocheilus.

Integr Zool 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory of Membrane Biology, Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, 100101, China.

The adaptive evolution of visual systems has been observed in many cavefish. However, little is known about the molecular mechanisms underlying these adaptations, which include regressive changes such as eye degeneration. Here, we analyzed phylogenetic and expression patterns of six eye-related genes (crx, foxg1b, opn1sw2, otx2, rho, and sox2) in twelve Sinocyclocheilus species from China including eight stygobionts and four stygophiles, and examined photoreceptor cell morphology of these species. Read More

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http://dx.doi.org/10.1111/1749-4877.12466DOI Listing

Control efficacy and joint toxicity of thiamethoxam mixed with spirotetramat against the Asian citrus psyllid, Diaphorina citri Kuwayama.

Pest Manag Sci 2020 Jul 11. Epub 2020 Jul 11.

Department of Entomology, Institute of Plant Protection, Hunan Academy of Agricultural Sciences, Changsha, 410125, China.

Background: The Asian citrus psyllid (ACP), Diaphorina citri Kuwayama, is one of the most devastating pests in citrus orchards, and has caused huge economic losses worldwide. Chemical control is the most effective way for psyllid control. Herein, the toxicity of nine insecticides to ACP adults and the joint action of thiamethoxam+spirotetramat were determined by a topical application method in the laboratory; field plot experiments were conducted to evaluate the control efficacy of one self-made thiamethoxam·spirotetramat 40% suspension concentrate (SC) comparing with thiamethoxam 21% SC, spirotetramat 22. Read More

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http://dx.doi.org/10.1002/ps.6004DOI Listing

Successful Treatment of Patients with Refractory High-Grade Serous Ovarian Cancer with GOPC-ROS1 Fusion Using Crizotinib: A Case Report.

Oncologist 2020 Jul 11. Epub 2020 Jul 11.

Geneplus-Beijing Ltd., Beijing, People's Republic of China.

Background: Recently, multiple poly (ADP-ribose) polymerase (PARP) inhibitors have demonstrated excellent efficacy among patients with ovarian cancer with or without BRCA mutations. However, alternative therapeutic options are urgently required for patients who cannot benefit from conventional chemotherapy or PARP inhibitors.

Case Presentation: A patient with high-grade serous ovarian carcinoma presented to our clinic after developing resistance to chemotherapy. Read More

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http://dx.doi.org/10.1634/theoncologist.2019-0609DOI Listing

Universal Access to Two-Dimensional Mesoporous Heterostructures via Micelle-Directed Interfacial Assembly.

Angew Chem Int Ed Engl 2020 Jul 11. Epub 2020 Jul 11.

The University of Queensland, School of Chemical Engineering and Australian Institute for Bioengineering and Nanotechnology (AIBN), Saint Lucia, 4072, Brisbane, AUSTRALIA.

Two-dimensional (2D) mesoporous heterostructures combining ultrathin nanosheet morphology, periodic porous surface structures and diverse hybrid compositions have recently emerged and become increasingly important for renewable energy storage and electronics. However, it remains a great challenge to develop a universal method to prepare 2D mesoporous heterostructures. Here, we report a composite micelle-directed interfacial assembly method to synthesize vertical heterostructures with ultrathin 2D material and two surrounding mesoporous monolayers assembled on both sides. Read More

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http://dx.doi.org/10.1002/anie.202007063DOI Listing

MicroRNA-142 regulates osteoblast differentiation and apoptosis of mouse pre-osteoblast cells by targeting bone morphogenetic protein 2.

FEBS Open Bio 2020 Jul 11. Epub 2020 Jul 11.

Department of Anesthesiology, Weifang People's Hospital, Weifang, Shandong Province, 261041, P. R. China.

Osteoporosis is a common disease that can seriously impair the physical and mental health of the elderly. However, current treatment is unsatisfactory, due to the lack of effective therapeutic targets. Abnormal expression and involvement of microRNA-142 (miR-142) have been identified in many diseases, including bone-related diseases. Read More

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http://dx.doi.org/10.1002/2211-5463.12929DOI Listing

Merging Electrosynthesis and Bifunctional Squaramide Catalysis in the Asymmetric Detrifluoroacetylative Alkylation Reactions.

Angew Chem Int Ed Engl 2020 Jul 11. Epub 2020 Jul 11.

University of Science and Technology of China, Hefei National Laboratory for Physical Sciences at the Microscale, No.96, JinZhai Road Baohe District, 230026, Hefei, CHINA.

An enantioselective bifunctional squaramide-catalyzed detrifluoroacetylative alkylation reaction under electrochemical conditions has been developed. The unified strategy based on this key tandem methodology has been divergently explored for the asymmetric synthesis of fluorine-containing target molecules with good stereocontrol (up to 95% ee ). Furthermore, this catalytic asymmetric detrifluoroacetylative alkylation reaction demonstrated the benefits of combining electrosynthesis and organocatalysis for the preparation of biologically relevant products containing C-F tertiary stereogenic center. Read More

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http://dx.doi.org/10.1002/anie.202006903DOI Listing

Outcomes of type A intramural hematoma: Influence of diabetes mellitus.

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

Department of Cardiovascular Surgery, The First Affiliated Hospital of Xiamen University, Teaching Hospital of Fujian Medical University, Xiamen, Fujian, China.

Objectives: We aimed to investigate whether uncomplicated type A intramural hematoma (IMHA) patients with type 2 diabetes mellitus (DM) who underwent a "wait-and-watch strategy" and tight glycemic control had similar clinical outcomes as patients without DM who received the same treatment strategy.

Methods: Between January 2010 and December 2016, uncomplicated IMHA patients with and without diabetes mellitus were included and were propensity score-matched to improve the balance between the two groups. Cox proportional hazard models were constructed to identify the specific factors associated with aorta-related mortality. Read More

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http://dx.doi.org/10.1111/jocs.14812DOI Listing

Astroglial N-myc downstream-regulated gene 2 protects the brain from cerebral edema induced by stroke.

Glia 2020 Jul 11. Epub 2020 Jul 11.

Department of Anesthesiology and Perioperative Medicine, Xijing Hospital, The Air Force Military Medical University, Xi'an, China.

Brain edema is a grave complication of brain ischemia and is the main cause of herniation and death. Although astrocytic swelling is the main contributor to cytotoxic edema, the molecular mechanism involved in this process remains elusive. N-myc downstream-regulated gene 2 (NDRG2), a well-studied tumor suppressor gene, is mainly expressed in astrocytes in mammalian brains. Read More

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http://dx.doi.org/10.1002/glia.23888DOI Listing

Variable selection for high-dimensional partly linear additive Cox model with application to Alzheimer's disease.

Stat Med 2020 Jul 11. Epub 2020 Jul 11.

Department of Statistics, University of Missouri, Columbia, Missouri, USA.

Variable selection has been discussed under many contexts and especially, a large literature has been established for the analysis of right-censored failure time data. In this article, we discuss an interval-censored failure time situation where there exist two sets of covariates with one being low-dimensional and having possible nonlinear effects and the other being high-dimensional. For the problem, we present a penalized estimation procedure for simultaneous variable selection and estimation, and in the method, Bernstein polynomials are used to approximate the involved nonlinear functions. Read More

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http://dx.doi.org/10.1002/sim.8594DOI Listing

Surgical results and pathological analysis of cardiac fibroma in the adolescent and the adult.

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

National Clinical Research Center of Cardiovascular Diseases, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

Backgrounds: Disparities may exist between the adolescent and the adult patients with cardiac fibromas in the symptoms, surgical outcomes, and pathological characteristics. The aim of this study was to compare short and midterm surgical outcomes of cardiac fibromas and to compare the biomarker expressions of tumor tissue samples between the adult and the adolescent.

Methods: Consecutive patients with the diagnosis of cardiac fibroma were admitted and received surgeries. Read More

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http://dx.doi.org/10.1111/jocs.14790DOI Listing

Dorsal hippocampus- and ACC-projecting medial septum neurons differentially contribute to the recollection of episodic-like memory.

FASEB J 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory of Medical Neurobiology and MOE Frontiers Center for Brain Science, School of Basic Medical Sciences, Institutes of Brain Science, Fudan University, Shanghai, China.

Episodic memory refers to the recollection of previous experiences containing specific temporal, spatial, and emotional information. The ability to recollect episodic memory requires coordination of multiple brain regions, including the hippocampus (HPC) and the cingulate cortex. While the afferents into HPC and cingulate cortex that orchestrate the episodic memory remain unclear. Read More

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http://dx.doi.org/10.1096/fj.202000398RDOI Listing

Adjuvant Transarterial Chemoembolization to Sorafenib in Unresectable Hepatocellular Carcinoma: A Meta-Analysis.

J Gastroenterol Hepatol 2020 Jul 11. Epub 2020 Jul 11.

Department of General Surgery, Sir Run-Run Shaw Hospital, Zhejiang University, Hangzhou, China.

Background And Aim: An increasing number of transarterial chemoembolization (TACE) plus sorafenib combination therapy has been applied for unresectable hepatocellular carcinoma (HCC). However, it remains controversial whether combination therapy is superior to sorafenib monotherapy. Therefore, we aimed to perform a meta-analysis to evaluate the efficacy and safety of the combination therapy of TACE plus sorafenib for unresectable HCC. Read More

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http://dx.doi.org/10.1111/jgh.15180DOI Listing

Long-term effectiveness of lycopene in the management of oral submucous fibrosis (OSMF): A 3 year follow-up study.

J Oral Pathol Med 2020 Jul 11. Epub 2020 Jul 11.

Department of Oral & Maxillofacial Surgery, Queen Alexandra Hospital, Portsmouth, UK.

Background: Long-term follow-ups after receiving lycopene therapy for management of Oral Submucous Fibrosis (OSMF) are scarce. The study aimed to assess the long-term efficacy of lycopene for management of OSMF symptoms.

Methods: In this prospective clinical study, 400 clinically diagnosed early OSMF patients were assessed for the efficacy of lycopene in alleviation of burning sensation (BS) and reduced mouth opening (MO) symptoms in comparison to placebo. Read More

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http://dx.doi.org/10.1111/jop.13085DOI Listing

The health sphere beyond borders: Coverage portability and justice in a global space.

Authors:
Adam K Webb

Bioethics 2020 Jul 11. Epub 2020 Jul 11.

Johns Hopkins University School of Advanced International Studies - Hopkins-Nanjing Centre, Nanjing, Jiangsu, China.

Medical coverage often stops at borders, for both travellers and long-term migrants. Such patchiness imposes a de facto limit on free movement. This article considers this phenomenon not as a mere policy choice or technical matter, but as a form of territorial discrimination that is incoherent and even unjust. Read More

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http://dx.doi.org/10.1111/bioe.12775DOI Listing

Genomic analyses reveal the genetic basis of early maturity and identification of loci and candidate genes in upland cotton (Gossypium hirsutum L.).

Plant Biotechnol J 2020 Jul 11. Epub 2020 Jul 11.

State Key Laboratory of Subtropical Silviculture, Zhejiang A & F University, Lin'an, Hangzhou, 311300, China.

Although upland cotton (Gossypium hirsutism L.) originated in the tropics, this early maturity cotton can be planted as far north as 46°N in China due to the accumulation of numerous phenotypic and physiological adaptations during domestication. However, how the genome of early maturity cotton has been altered by strong human selection remains largely unknown. Read More

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http://dx.doi.org/10.1111/pbi.13446DOI Listing

A case report and literature review of vaginal bleeding in prepubertal girl.

Acta Paediatr 2020 Jul 11. Epub 2020 Jul 11.

Department of Gynecology, Zhejiang Provincial People's Hospital, People's Hospital Of Hangzhou Medical College, Hangzhou, P.R. China.

Vaginal bleeding in the prepubertal girl is an uncommon condition with complex etiological factors. We report a case of a 6-year-old girl brought to hospital when vaginal bleeding was noticed after defecation. Various common causes were excluded by genital and auxiliary examinations. Read More

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http://dx.doi.org/10.1111/apa.15479DOI Listing

Mouse Double Minute 2 Amplification in Esophageal Squamous Cell Carcinoma Associated with Better Outcome.

Histopathology 2020 Jul 11. Epub 2020 Jul 11.

Department of Pathology, Zhongshan Hospital, Fudan University, Shanghai, 200032, P. R. China.

Aims: This study aimed to determine the frequency of mouse double minute 2 (MDM2) amplification in esophageal squamous cell carcinomas (ESCC) and to clarify its prognostic significance.

Methods: We investigated MDM2 amplification on tissue microarrays, using fluorescence in situ hybridization and analyzed its correlations with clinicopathological features and outcomes in 515 Chinese ESCC patients.

Results: MDM2 amplifications were found in 37 of 515 ESCC patients (7. Read More

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http://dx.doi.org/10.1111/his.14208DOI Listing

Successful resection of a huge schwannoma of the aortic root with 5-years follow-up.

Authors:
Zhixiong Huang

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

Department of Cardiovascular Surgery, Cardiovascular Institute, Fu Wai Hospital, Chinese Academy of Medical Science, Peking Union Medical College, Beijing, China.

Primary benign schwannomas of the heart are very rare. We report the case of a patient with a huge schwannoma of unique aortic origin. The complete resection of the rare tumor has been successfully performed. Read More

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http://dx.doi.org/10.1111/jocs.14797DOI Listing

Type A aortic dissection in the East and West: A comparative study between two hospitals from China and the US.

J Card Surg 2020 Jul 11. Epub 2020 Jul 11.

Department of Cardiac Surgery, Massachusetts General Hospital, Boston, Massachusetts.

Background: In this study, we compare the clinical characteristics, intraoperative management, and postoperative outcomes of patients with acute type A aortic dissection (ATAAD) between two academic medical hospitals in the United States and China.

Methods: From January 2011 to December 2017, 641 and 150 patients from Nanjing Drum Tower Hospital (NDTH) and Massachusetts General Hospital (MGH) were enrolled. Patient demographics, clinical features, surgical techniques, and postoperative outcomes were compared. Read More

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http://dx.doi.org/10.1111/jocs.14766DOI Listing
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