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    A density gradient of VAPG peptides on a cell-resisting surface achieves selective adhesion and directional migration of smooth muscle cells over fibroblasts.
    Acta Biomater 2018 Apr 7. Epub 2018 Apr 7.
    MOE Key Laboratory of Macromolecular Synthesis and Functionalization, Department of Polymer Science and Engineering, Zhejiang University, Hangzhou 310027, China; Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Hangzhou 310058, China. Electronic address:
    Selective adhesion and migration of smooth muscle cells (SMCs) over fibroblasts (FIBs) is required to prevent adventitia fibrosis in vascular regeneration. In this study, a uniform cell-resisting layer of poly(ethylene glycol) (PEG) with a density gradient of azide groups was generated on a substrate by immobilizing two kinds of PEG molecules in a gradient manner. A density gradient of alkynyl-functionalized Val-Ala-Pro-Gly (VAPG) peptides was then prepared on the PEG layer via click chemistry. Read More

    Magnetic resonance imaging-a diagnostic tool for postoperative evaluation of dental implants: a case report.
    Oral Surg Oral Med Oral Pathol Oral Radiol 2018 Apr 31;125(4):e103-e107. Epub 2018 Jan 31.
    Department of Oral and Maxillofacial Surgery, Medical Center - University of Freiburg, Faculty of Medicine, University of Freiburg, Freiburg, Germany.
    Objective: Compared with cone beam computed tomography (CBCT), magnetic resonance imaging (MRI) might be superior for the diagnosis of nerve lesions associated with implant placement.

    Study Design: A patient presented with unilateral pain associated with dysesthesia in the region of the right lower lip and chin after implant placement. Conventional orthopantomography could not identify an association between the position of the inferior alveolar nerve and the implant. Read More

    Chin remodeling in a patient with bimaxillary protrusion and open bite by using mini-implants for temporary anchorage.
    Am J Orthod Dentofacial Orthop 2018 Mar;153(3):436-444
    State Key Laboratory of Oral Diseases, National Clinical Research Center for Oral Diseases, Department of Orthodontics, West China Hospital of Stomatology, Sichuan University, Chengdu, Sichuan, China. Electronic address:
    Patients with bimaxillary protrusion may have an unattractive profile with a retruded chin contour. Correction of the severely protrusive anterior alveolar bone and teeth combined with a moderate open bite without orthognathic surgery can be challenging. This case report describes the orthodontic treatment of a woman with severe bimaxillary protrusion and a moderate open bite. Read More

    Calcar screw position in proximal humerus fracture fixation: Don't miss high!
    Injury 2018 Mar 11;49(3):624-629. Epub 2018 Feb 11.
    Biedermann Lab for Orthopaedic Research, University of Pennsylvania, Department of Orthopaedic Surgery, Philadelphia, PA, United States. Electronic address:
    Introduction: In locked plate fixation of proximal humerus fractures, the calcar is an important anchor point for screws providing much-needed medial column support. Most locking plate implants utilize a fixed-trajectory locking screw to achieve this goal. Consequently, adjustments of plate location to account for patient-specific anatomy may result in a screw position outside of the calcar. Read More

    [The application progress of 3D printing technology in ophthalmology].
    Zhonghua Yan Ke Za Zhi 2018 Jan;54(1):72-76
    Tianjin Eye Hospital and Institute, Clinical College of Ophthalmology of Tianjin Medical University, Tianjin Key Laboratory of Ophthalmology and Vision Science, Tianjin 300020, China.
    3D printing is a kind of technology that makes 3D models from computer-aided designs through additive manufacturing, in which successive layers of the material are deposited onto underlying layers to construct 3D objects. In recent years, 3D printing is gradually applied in the field of ophthalmology, such as the cornea, retina, orbital operation, ocular tumor radiotherapy, ocular implants and ophthalmology teaching. This article reviews the application status of 3D printing technology in the basic research and clinical treatment in ophthalmology. Read More

    Adverse Events in Facial Implant Surgery and Associated Malpractice Litigation.
    JAMA Facial Plast Surg 2018 Jan 18. Epub 2018 Jan 18.
    Department of Otolaryngology-Head and Neck Surgery, Wayne State University School of Medicine, Detroit, Michigan.
    Importance: Facial implants represent an important strategy for providing instant and long-lasting volume enhancement to address both aging and posttraumatic defects.

    Objective: To better understand risks of facial implants by examining national resources encompassing adverse events and considerations facilitating associated litigation.

    Design, Setting, And Participants: A cross-sectional study reviewed complications following facial implants. Read More

    Soft Artificial Bladder Detrusor.
    Adv Healthc Mater 2018 Mar 15;7(6):e1701014. Epub 2018 Jan 15.
    Soft Matter Research Center, Key Laboratory of Soft Machines and Smart Devices of Zhejiang Province, Department of Engineering Mechanics, Zhejiang University, Hangzhou, Zhejiang, 310027, P. R. China.
    Developing soft devices for invasive procedures bears great importance for human health. The softness and large strain actuation of responsive hydrogels promise the potential to fabricate soft devices, which can attach on and assist to the function of organs. The key challenges lie in the fabrication of soft devices with robust actuating ability and biocompatibility to the attached organ. Read More

    Treatment Approach to Severe Microgenia Cases: Combined Use of Osseous and Implant Genioplasty.
    J Craniofac Surg 2018 Mar;29(2):e175-e179
    Department of Plastic, Reconstructive and Aesthetic Surgery, Gazi University Hospital, Department of Plastic, Reconstructive and Aesthetic Surgery, Ankara.
    Introduction: As well as the chin is an important esthetic unit of the facial structure, it is also the region having a key role in the appearance of the face. Correction of cosmetic and functional deformities that may occur in this region because of serious hypoplasia (microgenia) is performed by chin augmentation. Chin augmentation is most frequently performed via implant or osseous genioplasty in the literature. Read More

    [Prosthetic genioplasty versus osseous genioplasty in aesthetic chin augmentation: Literature review and knowledge update].
    Ann Chir Plast Esthet 2017 Dec 4. Epub 2017 Dec 4.
    Université Paris-Diderot, Sorbonne-Paris-Cité, 5, rue Thomas-Mann, 75013 Paris, France; Hôpital Saint-Louis, AP-HP, 75010 Paris, France.
    Chin augmentation is commonly practiced, whether in microgenia treatment, in cases of orthognathic or cosmetic surgery. Located at the crossroads of many specialties, the technique choice still differs according to the surgeon specialiy. A large number of publications on the subject are available. Read More

    A Novel Technique of Fabricating a Modified Removable Provisional Prosthesis over an Autologous Bone Grafted Maxillary Anterior Edentulous Segment Prior to Implant Placement.
    J Clin Diagn Res 2017 Sep 1;11(9):ZH01-ZH02. Epub 2017 Sep 1.
    Tutor, Department of Prosthodontics, Rajah Muthiah Dental College, Annamalai University, Chidambaram, Tamil Nadu, India.
    Implant dentistry has provided a lot of surgical as well as prosthetic techniques for improving the success of the implants. The surgical technique commonly followed now prior to implant placement is bone grafting procedure. One of the commonest techniques is the use of autologous block graft harvested from mandibular chin region. Read More

    Peptide-Functionalized Polyurethane Coatings Prepared via Grafting-To Strategy to Selectively Promote Endothelialization.
    Adv Healthc Mater 2018 Mar 4;7(5). Epub 2017 Dec 4.
    Institute of Bioengineering and Nanotechnology, 31 Biopolis Way, The Nanos, 138669, Singapore, Singapore.
    Endothelialization, formation of endothelial cells (ECs) layer on cardiovascular implant surface, is considered an ideal approach to prevent restenosis (renarrowing of blood vessel mainly due to the accumulation of proliferated vascular smooth muscle cells, SMCs) and thrombosis. In this study, the possibility of using polyurethane (PU) as a coating platform for functionalization with peptide to enhance endothelialization on implants is explored. PUs are synthesized through metal-free organocatalytic polymerization followed by chemical conjugation with an EC-specific REDV peptide through thiol-ene reaction. Read More

    Minimally Invasive Crestal Sinus Lift Technique and Simultaneous Implant Placement.
    Chin J Dent Res 2017;20(4):211-218
    Objective: To evaluate the effectiveness and clinical results of a new crestal sinus lift technique used to elevate the sinus floor simultaneously with bone grafts and implant placement.

    Methods: Eleven patients underwent this crestal sinus lift technique performed using an SCA KIT. The mean residual bone height was 6. Read More

    Anatomical landmarks of mandibular interforaminal region related to dental implant placement with 3D CBCT: comparison between edentulous and dental mandibles.
    Surg Radiol Anat 2017 Nov 9. Epub 2017 Nov 9.
    Department of Oral and Maxillofacial Radiology, School of Dentistry, Ege University, Izmir, Turkey.
    Background: Anterior mandibular (interforaminal) region is important in implant applications as it serves a basis for neurovascular bedding and holds the prosthesis for patients. Treatment planning for dental implant patients is often complicated by the unknown extent of the anterior loop of the neurovascular bundle. Anatomical structures including mandibular incisive canal (MIC) and lingual foramen (LF) should also be examined as part of the detailed analysis for their neurovascular structures. Read More

    Computer-Assisted Planning and 3D Printing-Assisted Modeling for Chin Augmentation.
    Aesthet Surg J 2017 Dec;38(1):1-10
    Private practice, Taipei, Taiwan (R.O.C.).
    Background: Patients are frequently not satisfied with the outcome of chin augmentation.

    Objectives: We report the use of three-dimensional (3D) imaging and printing to design custom fit porous polyethylene chin implants.

    Methods: Patients requesting chin augmentation received 3D computed tomography (CT) imaging of the facial area. Read More

    Male Surgical Neck Rejuvenation.
    Dermatol Surg 2017 Nov;43 Suppl 2:S203-S207
    *Private Practice, Dermatology, Beverly Hills, California; †Loyola University Medical Center, Department of Dermatology, La Grange Park, Illinois.
    Background: Patients who are aging, with weight gain, and increased skin laxity, request dermatologists to improve their neck area. Surgical and nonsurgical options are reviewed as well as benefits and side effects. This article will focus on how surgical techniques can be applied for male patients in particular. Read More

    Characteristics of Mandarin Open-set Word Recognition Development among Chinese Children with Cochlear Implants.
    Chin Med J (Engl) 2017 Oct;130(20):2410-2415
    Department of Otolaryngology, Head and Neck Surgery, Beijing Tongren Hospital, Capital Medical University, Key Laboratory of Otolaryngology Head and Neck Surgery, Capital Medical University, Ministry of Education, Beijing 100730, China.
    Background: Cochlear implants (CIs) can improve speech recognition for children with severe congenital hearing loss, and open-set word recognition is an important efficacy measure. This study examined Mandarin open-set word recognition development among Chinese children with CIs and normal hearing (NH).

    Methods: This study included 457 children with CIs and 131 children with NH, who completed the Mandarin lexical neighborhood test. Read More

    Expanding the Criteria for Nipple-Sparing Mastectomy in Patients With Poor Prognostic Features.
    Clin Breast Cancer 2017 Aug 24. Epub 2017 Aug 24.
    Department of Breast Surgery, Columbia University Medical Center, New York, NY. Electronic address:
    Background: In this study we aimed to review the outcomes of nipple-sparing mastectomy (NSM) in the setting of expanded criteria: previous breast surgery/irradiation, neoadjuvant chemotherapy (NAC), post-NSM irradiation, and to assess conversion to acceptable criteria after NAC.

    Patients And Methods: In this single-institution institutional review board-approved retrospective review, we identified patients who underwent NSM after previous breast intervention or NAC from January 2010 to February 2017. Clinicopathologic features, previous breast surgeries, response rate, complications, and recurrences were recorded. Read More

    Bone Ring Augmentation Around Immediate Implants: A Clinical and Radiographic Study.
    Ann Maxillofac Surg 2017 Jan-Jun;7(1):92-97
    Department of Oral and Maxillofacial Surgery, Government Dental College and Research Institute, Bengaluru, Karnataka, India.
    Purpose: The purpose of this study was to evaluate the efficacy of bone ring augmentation technique for three-dimensional augmentation of severely defective sockets along with placement of immediate dental implants.

    Materials And Methods: A clinical study was conducted on 14 patients with 15 defective sockets requiring extractions and immediate implant placement. Following extraction, bone ring with an implant osteotomy, harvested from chin, was sculptured and fitted into the extraction socket. Read More

    Five year results of the prospective randomized controlled prostatic urethral L.I.F.T. study.
    Can J Urol 2017 Jun;24(3):8802-8813
    University of Texas Southwestern Medical Center, Dallas, Texas, USA.
    Introduction: To report the five year results of a prospective, multi-center, randomized, blinded sham control trial of the Prostatic Urethral Lift (PUL) in men with bothersome lower urinary tract symptoms (LUTS) due to benign prostatic hyperplasia (BPH).

    Materials And Methods: At 19 centers in North America and Australia, 206 subjects ≥ 50 years old with International Prostate Symptom Score (IPSS ) > 12, peak flow rate (Qmax) ≤ 12 mL/s, and prostate volume 30 cc-80 cc were randomized 2:1 to the PUL procedure or blinded sham control. In PUL permanent UroLift implants are placed to hold open the lateral lobes of the prostate to reduce urinary obstruction. Read More

    Characterizing infections in prosthetic breast reconstruction: A validity assessment of national health databases.
    J Plast Reconstr Aesthet Surg 2017 Oct 18;70(10):1345-1353. Epub 2017 May 18.
    Division of Plastic and Reconstructive Surgery, Department of Surgery, University of Rochester Medical Center, Rochester, NY, USA.
    Introduction: Current guidelines in the United States require reporting only the 30-day postoperative outcomes to standardized databases, including the National Surgical Quality Improvement Program (NSQIP). Thus, many breast implant-related complications go unreported in standard databases. We sought to characterize late periprosthetic infections following implant-based breast reconstruction. Read More

    Effects of Combining Insulin-like Growth Factor 1 and Platelet-derived Growth Factor on Osteogenesis around 
Dental Implants.
    Chin J Dent Res 2017;20(2):105-109
    Objective: To explore the effects of the combination of insulin-like growth factor 1 (IGF-1) and platelet-derived growth factor (PDGF) on bone formation around dental implants.

    Methods: A total of 24 adult rabbits were included in this experiment. Titanium machine-polished dental implants were placed in the iliac bones to simulate dental implants in the alveolar bone. Read More

    Cheek and Chin Implants to Enhance Facelift Results.
    Facial Plast Surg 2017 Jun 1;33(3):279-284. Epub 2017 Jun 1.
    Facial Plastic Surgery Associates, 6655 Travis Street, Suite 900, Houston, Texas.
    The traditional rhytidectomy addresses facial and neck aging as it relates to soft tissue laxity. The modern volumetric facelift provides optimal results by addressing not only skin laxity but also the loss of volume secondary to tissue atrophy and bony resorption. While multiple techniques including fat grafting, dermal fillers, and tissue resuspension are used to correct the tissue loss, alloplastic midface augmentation remains the most permanent method. Read More

    Increasing the accuracy of mandibular reconstruction with free fibula flaps using functionalized selective laser-melted patient-specific implants: A retrospective multicenter analysis.
    J Craniomaxillofac Surg 2017 Aug 19;45(8):1212-1219. Epub 2017 Apr 19.
    Department of Craniomaxillofacial Surgery, Hannover Medical School, Germany.
    In this study, selective laser melted patient specific functional implants (PSFI) were utilised in combination with a fibula free flap, for mandible reconstruction. The shape and length of the PSFI, the shaping of fibula graft, its angulation and the length of the screws, were virtually planned before the surgery. Information, such as resection margin and screw lengths, were coded on the implant. Read More

    Ipsilateral proximal and shaft femoral fractures.
    Chin J Traumatol 2017 Jun 19;20(3):155-157. Epub 2017 Apr 19.
    Department of Orthopaedic and Traumatology Surgery, Cotonou Teaching Hospital, Jericho Cotonou, Benin.
    Purpose: To study the management and evaluate anatomical and functional outcomes of patients with ipsilateral proximal and shaft femoral fractures.

    Methods: A retrospective, descriptive and analytic study lasted for ten years and a half ranging from January 1, 2005 to June 30, 2015. The following parameters were studied: epidemiology, fracture characteristics, therapeutic, anatomical and functional outcomes. Read More

    In vitro study of electrodeposited fluoridated hydroxyapatite coating on G-II titanium with a nanostructured TiO interlayer.
    Biomed Mater 2017 04 4;12(2):025018. Epub 2017 Apr 4.
    Department of Mechanical Engineering, National Chin-Yi University of Technology, Taichung 411, Taiwan.
    Titanium and its alloys have been widely used as orthopedic and dental implants for several decades due to their superior mechanical properties, corrosion resistance and biocompatibility. Recently, many researches revealed that the hydroxyapatite coatings on biomedical materials can further improve their biocompatibility and bioactivity. However, hydroxyapatite coatings are easily decomposed, weakening the bonding between implants and bone tissues and resulting in a high dissolution rate in the biological environment. Read More

    Two-Armed Activation of Bone Mineral Deposition by the Flavones Baicalin and Baicalein, Encapsulated in Polyphosphate Microparticles.
    Am J Chin Med 2017 2;45(3):533-555. Epub 2017 Apr 2.
    * ERC Advanced Investigator Grant Research Group at the Institute for Physiological Chemistry, University Medical Center of the Johannes Gutenberg University, D-55128 Mainz, Germany.
    In this study, we investigated the effect of the two flavonoids, baicalin (baicalein 7-O-[Formula: see text]- d-glucuronic acid) and its aglycone, baicalein (5,6,7-trihydroxyflavone), after encapsulation into amorphous calcium polyphosphate (Ca-polyP) microparticles on mineralization of primary human osteoblasts (phOSB). Both flavonoids, which come from root extracts of Scutellaria baicalensis Georgi, are used in Traditional Chinese Medicine, and are nontoxic in cells up to a concentration of 3[Formula: see text][Formula: see text]g/ml. The morphogenetically active, energy-rich Ca-polyP particles with a stoichiometric P:Ca ratio of 1:2 are degraded by cellular alkaline phosphatase (ALP) to ortho-phosphate used for bone hydroxyapatite formation. Read More

    Management of Esophageal and Pharyngeal Perforation as Complications of Anterior Cervical Spine Surgery.
    World Neurosurg 2017 Jun 9;102:275-283. Epub 2017 Mar 9.
    Department of Neurosurgery, Gangnam Severance Hospital, Spine and Spinal Cord Institute, Yonsei University College of Medicine, Seoul, South Korea.
    Objective: To describe our experience in treating esophageal and pharyngeal perforation after anterior cervical spine surgery.

    Methods: Six patients with esophageal injury and one patient with pharyngeal injury after anterior cervical spinal surgery, managed at our department between 2000 and 2015, were analyzed retrospectively.

    Results: During the study period, 7 patients (6 male and 1 female; mean age, 45 years) presented with esophageal perforation. Read More

    Cost-Effectiveness Analysis of Quadripolar Versus Bipolar Left Ventricular Leads for Cardiac Resynchronization Defibrillator Therapy in a Large, Multicenter UK Registry.
    JACC Clin Electrophysiol 2017 Feb;3(2):107-116
    Imaging Sciences & Biomedical Engineering, King's College London, London, United Kingdom; Department of Cardiology, Guy's and St Thomas' NHS Foundation Trust, London, United Kingdom.
    Objectives: The objective of this study was to evaluate the cost-effectiveness of quadripolar versus bipolar cardiac resynchronization defibrillator therapy systems.

    Background: Quadripolar left ventricular (LV) leads for cardiac resynchronization therapy reduce phrenic nerve stimulation (PNS) and are associated with reduced mortality compared with bipolar leads.

    Methods: A total of 606 patients received implants at 3 UK centers (319 Q, 287 B), between 2009 and 2014; mean follow-up was 879 days. Read More

    Improvement of Implant Placement after Bone Augmentation of Severely Resorbed Maxillary Sinuses with 'Tent-Pole' Grafting Technique in Combination with rhBMP-2.
    Chin J Dent Res 2017;20(1):9-17
    Objective: To study the clinical effect of short implant placement using osteotome sinus floor elevation technique and tent-pole grafting technique with recombinant human bone morphogenetic protein 2 (rhBMP-2) in severely resorbed maxillary area.

    Methods: Eleven patients with insufficient bone height in the posterior maxillary area were included. According to the native bone height and crown height space (CHS), the patients were divided into two groups: immediate placement of short implants with simultaneous bone augmentation (group A, 5 patients) and delayed dental implant placement (4 to 6 months) after bone augmentation. Read More

    Histomorhological and clinical evaluation of maxillary alveolar ridge reconstruction after craniofacial trauma by applying combination of allogeneic and autogenous bone graft.
    Chin J Traumatol 2017 Feb 20;20(1):14-17. Epub 2017 Jan 20.
    Department of Biomedical and Dental Sciences and Morphofunctional Imaging, Messina University, AOU Policlinico "G. Martino", Via C. Valeria 98100 Messina, Italy. Electronic address:
    A variety of techniques and materials for the rehabilitation and reconstruction of traumatized maxillary ridges prior to dental implants placement have been described in literature. Autogenous bone grafting is considered ideal by many researchers and it still remains the most predictable and documented method. The aim of this report is to underline the effectiveness of using allogeneic bone graft for managing maxillofacial trauma. Read More

    The use of virtual surgical planning and navigation in the treatment of orbital trauma.
    Chin J Traumatol 2017 Feb 21;20(1):9-13. Epub 2017 Jan 21.
    Odontostomatologic Surgery, University of Milan, Milan 20122, Italy.
    Virtual surgical planning (VSP) has recently been introduced in craniomaxillofacial surgery with the goal of improving efficiency and precision for complex surgical operations. Among many indications, VSP can also be applied for the treatment of congenital and acquired craniofacial defects, including orbital fractures. VSP permits the surgeon to visualize the complex anatomy of craniofacial region, showing the relationship between bone and neurovascular structures. Read More

    Efficacy of the Intravitreal Sustained-Release Dexamethasone Implant for Diabetic Macular Edema Refractory to Anti-Vascular Endothelial Growth Factor Therapy: Meta-Analysis and Clinical Implications.
    Ophthalmic Surg Lasers Imaging Retina 2017 02;48(2):160-166
    Background And Objective: To assess the effect on best-corrected visual acuity (BCVA) and efficacy of the intravitreal sustained-release 0.7 mg dexamethasone implant (Ozurdex; Allergan, Irvine, CA) in patients with recalcitrant diabetic macular edema (DME).

    Patients And Methods: Meta-analysis utilizing the MOOSE framework and a random effects model. Read More

    The Influences of Different Ratios of Biphasic Calcium Phosphate and Collagen Augmentation on Posterior Lumbar Spinal Fusion in Rat Model.
    Yonsei Med J 2017 Mar;58(2):407-414
    Department of Neurosurgery, Spine and Spinal Cord Institute, Yonsei University College of Medicine, Seoul, Korea.
    Purpose: To determine the influence of different ratios of hydroxyapatite (HA)/beta tricalcium phosphate (β-TCP) and collagen augmentation for posterior lumbar fusion in a rat model.

    Materials And Methods: We generated a posterior lumbar fusion model in 50 rats and divided it into five groups of equal number as follows; 1) autologous bone graft as group A, 2) 70% HA+30% β-TCP as group B, 3) 70% HA+30% β-TCP+collagen as group C, 4) 30% HA+70% β-TCP as group D, and 5) 30% HA+70% β-TCP+collagen as group E. Rats were euthanized at 12 weeks after surgery and fusion was assessed by manual palpation, quantitative analysis using microCT and histology. Read More

    Alignment of collagen fiber in knitted silk scaffold for functional massive rotator cuff repair.
    Acta Biomater 2017 03 16;51:317-329. Epub 2017 Jan 16.
    Dr. Li Dak Sum & Yip Yio Chin Center for Stem Cell and Regenerative Medicine, Zhejiang University, Zhejiang 310000, China; Key Laboratory of Tissue Engineering and Regenerative Medicine of Zhejiang Province, School of Medicine, Zhejiang University, Zhejiang 310009, China; Department of Sports Medicine, School of Medicine, Zhejiang University, Zhejiang 310000, China; China Orthopaedic Regenerative Medicine (CORMed), Hangzhou, China.
    Rotator cuff tear is one of the most common types of shoulder injuries, often resulting in pain and physical debilitation. Allogeneic tendon-derived decellularized matrices do not have appropriate pore size and porosity to facilitate cell infiltration, while commercially-available synthetic scaffolds are often inadequate at inducing tenogenic differentiation. The aim of this study is to develop an advanced 3D aligned collagen/silk scaffold (ACS) and investigate its efficacy in a rabbit massive rotator cuff tear model. Read More

    Chin Symphysis Bone, Allograft, and Platelet-Rich Fibrin: Is the Combination Effective in Repair of Alveolar Cleft?
    J Oral Maxillofac Surg 2017 May 26;75(5):1026-1035. Epub 2016 Dec 26.
    Associate Professor, Torabinejad Dental Research Center, Department of Oral and Maxillofacial Radiology, School of Dentistry, Isfahan University of Medical Sciences, Isfahan, Iran.
    Purpose: Secondary grafting of alveolar defects with iliac crest bone is a common treatment method in cleft patients. The aim of this study was to evaluate the effectiveness of the combination of symphysis bone, allograft, and platelet-rich fibrin in regeneration of alveolar defects compared with iliac bone graft.

    Materials And Methods: In this randomized clinical trial, patients with unilateral alveolar defects were divided randomly into two categories. Read More

    Long-standing chin-augmenting costochondral graft creating a diagnostic challenge: A case report and literature review.
    Imaging Sci Dent 2016 Dec 20;46(4):279-284. Epub 2016 Dec 20.
    Department of Oral and Maxillofacial Diagnostic Sciences, Oral and Maxillofacial Radiology, College of Dentistry, University of Florida, Gainesville, FL, USA.
    To our knowledge, the imaging features of costochondral grafts (CCGs) on cone-beam computed tomography (CBCT) have not been documented in the literature. We present the case of a CCG in the facial soft tissue to the anterior mandible, with changes mimicking a cartilaginous neoplasm. This is the first report to describe the CBCT imaging features of a long-standing graft in the anterior mandible. Read More

    Bone resorption under chin implants: The orthodontist's role in its diagnosis and management.
    Am J Orthod Dentofacial Orthop 2017 Jan;151(1):201-208
    Private practice, San Juan, Puerto Rico; Post-Graduate Program, Department of Orthodontics, School of Dental Medicine, University of Puerto Rico, San Juan; consultant, San Jorge Children's Hospital/Plastic and Reconstructive Institute, San Juan, Puerto Rico. Electronic address:
    Alloplastic chin implants have been a valuable treatment modality for the correction of microgenia. Their use has provided satisfactory esthetic results by improving facial balance. However, bone resorption under these implants can occur. Read More

    Porous Polyethylene Implant as Aesthetic Complement in Orthognathic Surgery.
    J Craniofac Surg 2016 Nov;27(8):e790-e791
    *Division of Oral and Maxillofacial Surgery, Department of Diagnosis and Surgery†Department of Orthodontics, Dental School at Araraquara-Unesp, Araraquara, Brazil.
    Porous polyethylene implants have been used as an alternative in the treatment of patients with zygomatic and paranasal projections deficiency. These implants promote a facial rejuvenating effect due to the attenuation of the nasal and chin prominences. The advantages of porous polyethylene include biocompatibility, dimensional stability, easy adaptation and fixation, low complication rate, and its availability in different sizes and shapes. Read More

    24-month durability after crossover to the prostatic urethral lift from randomised, blinded sham.
    BJU Int 2016 Oct;118 Suppl 3:14-22
    Austin Health, Heidelberg, Vic., Australia.
    Objective: To evaluate the 24-month effectiveness of the prostatic urethral lift (PUL) procedure in men with lower urinary tract symptoms (LUTS) secondary to benign prostatic hyperplasia (BPH) assessed through a crossover study.

    Patients And Methods: In all, 53 patients underwent a sham procedure as part of the blinded, randomised L.I. Read More

    Retina 2016 Nov;36(11):2087-2092
    *The Bernard and Shirlee Brown Glaucoma Laboratory, Departments of Ophthalmology, Pathology and Cell Biology, Institute of Human Nutrition, College of Physicians and Surgeons, Columbia University, New York, New York; †Omics Laboratory, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa; ‡Vitreoretinal Service, Department of Ophthalmology and Visual Sciences, University of Iowa, Iowa City, Iowa; §Retina Consultants of Southern California, Redlands, California; and ¶VitreoRetinal Surgery, Minneapolis, Minnesota.
    Purpose: To evaluate the safety and efficacy of combining intravitreal dexamethasone implantation (Ozurdex) with pars plana vitrectomy (PPV).

    Methods: A retrospective review was conducted on cases where Ozurdex injection was performed in the operating room in conjunction with pars plana vitrectomy. Our primary outcome measure was the presence of surgical complications in the perioperative and 3-month postoperative window. Read More

    [Correction of congenital malformations by custom-made silicone implants: Contribution of computer-aided design. Experience of 611 cases].
    Ann Chir Plast Esthet 2016 Oct 1;61(5):694-702. Epub 2016 Jul 1.
    Service de chirurgie plastique et reconstructrice, CHU de Toulouse Rangueil, 1, avenue Jean-Poulhès, TSA 50032, 31059 Toulouse cedex 9, France.
    Introduction: Modern techniques of computer-aided design and tridimensional prototyping for manufacturing silicone elastomer custom implants are growing. They have widely modified the surgical indications in our unit.

    Materials And Methods: By presenting their experience of 611 cases managed between 1993 and 2016, the authors describe the method of conception from CT-scans, the virtual image of the body and the manufacture of the custom-made implant perfectly adapted to the anatomy of each one. Read More

    Minimally Invasive Cochlear Implantation Assisted by Bi-planar Device: An Exploratory Feasibility Study .
    Chin Med J (Engl) 2016 10;129(20):2476-2483
    Department of Otorhinolarygology - Head and Neck Surgery, Peking University Third Hospital, Beijing 100191, China.
    Background: A single drilled tunnel from the lateral mastoid cortex to the cochlea via the facial recess is essential for minimally invasive cochlear implant surgery. This study aimed to explore the safety profile of this kind of new image-guided and bi-planar device-assisted surgery procedure in vitro.

    Methods: Image-guided minimally invasive cochlear implantations were performed on eight cadaveric temporal bone specimens. Read More

    pH and redox dual-responsive biodegradable polymeric micelles with high drug loading for effective anticancer drug delivery.
    Nanomedicine 2017 02 6;13(2):431-442. Epub 2016 Oct 6.
    Institute of Bioengineering and Nanotechnology, Singapore 138669, Singapore. Electronic address:
    Diblock copolymers of poly(ethylene glycol) (PEG) and biodegradable polycarbonate functionalized with GSH-sensitive disulfide bonds and pH-responsive carboxylic acid groups were synthesized via organocatalytic ring-opening polymerization of functional cyclic carbonates with PEG having different molecular weights as macroinitiators. These narrowly-dispersed polymers had predictable molecular weights, and were used to load doxorubicin (DOX) into micelles primarily through ionic interactions. The DOX-loaded micelles exhibited the requisite small particle size (<100 nm), narrow size distribution and high drug loading capacity. Read More

    Avoiding Errors in the Management of Pediatric Polytrauma Patients.
    Instr Course Lect 2016 Feb;65:345-352
    Orthopaedic Resident, Department of Orthopaedics, University of Maryland, Baltimore, Maryland.
    Management of pediatric polytrauma patients is one of the most difficult challenges for orthopaedic surgeons. Multisystem injuries frequently include complex orthopaedic surgical problems that require intervention. The physiology and anatomy of children and adolescent trauma patients differ from the physiology and anatomy of an adult trauma patient, which alters the types of injuries sustained and the ideal methods for management. Read More

    Solid Implants in Facial Plastic Surgery: Potential Complications and How to Prevent Them.
    Facial Plast Surg 2016 Oct 28;32(5):520-31. Epub 2016 Sep 28.
    Department of Otolaryngology Head and Neck Surgery, Medical University of South Carolina, Charleston, South Carolina.
    Allogenic implants are an effective alternative to autologous grafts in the reconstruction of facial defects. These implants are used to reconstruct a variety of bony and soft-tissue defects, including the frontal and temporal regions; internal orbit; infraorbital rim; malar, paranasal, and nasal regions; mandible; and chin. In comparison to their autologous counterparts, alloplastic materials are more readily available, lack donor-site morbidity, decrease surgical time and cost, and still have relatively good postoperative tissue tolerance. Read More

    Clinical Outcomes With Midline Cortical Bone Trajectory Pedicle Screws Versus Traditional Pedicle Screws in Moving Lumbar Fusions From Hospitals to Outpatient Surgery Centers.
    Clin Spine Surg 2017 Jul;30(6):E791-E797
    *Herbert Wertheim College of Medicine at Florida International University †Charles E. Schmidt College of Medicine at Florida Atlantic University, Miami ‡Less Exposure Surgery Specialists Institute (LESS Institute) §Less Exposure Surgery (LES) Society, Fort Lauderdale, FL.
    Study Design: Level III.

    Objective: To report on the outcomes of midline cortical bone trajectory (CBT) pedicle screw surgical technique for posterior lumbar fixation in the outpatient surgery center (OSC) compared with traditional pedicle screws in the hospital.

    Summary Of Background Data: Traditional pedicle screws have been the gold standard for posterior lumbar fusion. Read More

    Incidence and predictors of radial nerve palsy with the anterolateral brachialis splitting approach to the humeral shaft.
    Chin J Traumatol 2016 Aug;19(4):217-20
    Department of Orthopaedics Unit 1, Christian Medical College, Vellore 632004, Tamil Nadu, India.
    Purpose: Fractures of the humeral shaft are common and account for 3%-5% of all orthopedic injuries. This study aims to estimate the incidence of radial nerve palsy and its outcome when the anterior approach is employed and to analyze the predictive factors.

    Methods: The study was performed in the department of orthopaedics unit of a tertiary care trauma referral center. Read More

    Comparative study of multiple cancellous screws versus sliding hip screws in femoral neck fractures of young adults.
    Chin J Traumatol 2016 Aug;19(4):209-12
    Department of Orthopedics, Post Graduate Institute of Medical Education and Research, Dr Ram Manohar Lohia Hospital, New Delhi 110001, India.
    Purpose: Both cannulated cancellous screw (CCS) and sliding hip screw (SHS) are used in femoral neck fracture fixations, but which is superior is yet to be determined. This study was aimed to compare the clinicoradiological outcome of femoral neck fracture treated with SHS or CCS in young adults.

    Methods: Adults (16e60 years) with femoral neck fracture were divided into Group 1 fixed with SHS and Group 2 fixed with three CCS after closed reduction. Read More

    Inserting the Ulnar Prosthesis into Radius as a Novel Salvage Surgery for Revision Total Elbow Arthroplasty with Massive Bone Defect.
    Chin Med J (Engl) 2016 Aug;129(16):1917-21
    Department of Orthopedic Trauma, Beijing Jishuitan Hospital, Beijing 100035, China.
    Background: Infection and aseptic loosening are common complications of total elbow arthroplasty (TEA) and often require revision surgery. However, bone defects, along with other complications, bring an extra difficulty to the second surgery, especially for patients with a massive bone defect in the proximal ulna. Several methods including allograft or autograft have been introduced into practice, but none sufficiently solves these problems. Read More

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