2,094,765 results match your criteria Child and Adolescent Psychiatric Clinics of North America[Journal]


Predictive Value of Age-Bilirubin-International Normalized Ratio-Creatinine Score in Short-Term Survival of Acute-on-Chronic Hepatitis B Liver Failure.

Cell Physiol Biochem 2018 11;51(5):2484-2495. Epub 2018 Dec 11.

Department of Hepatic Surgery, The Third Affiliated Hospital, Sun Yat-sen University, Guangdong, China.

Background/aims: The age-bilirubin-international normalized ratio-creatinine (ABIC) score, which is a predictive model commonly used for alcoholic hepatitis, has not yet been studied in acute-on-chronic hepatitis B liver failure (HBV-ACLF). We aimed to investigate the predictive value of the ABIC score in patients with HBV-ACLF.

Methods: This retrospective study involved 398 patients diagnosed with HBV-ACLF, who were divided into a training cohort of 305 patients and a validation cohort of 93 patients. Read More

View Article
December 2018

Gonadotropin- and Adrenocorticotropic Hormone-Independent Precocious Puberty of Gonadal Origin in a Patient with Adrenal Hypoplasia Congenita Due to DAX1 Gene Mutation - A Case Report and Review of the Literature: Implications for the Pathomechanism.

Horm Res Paediatr 2018 Dec 11:1-10. Epub 2018 Dec 11.

Division of Pediatric Endocrinology and Diabetes, Department of Pediatrics and Adolescent Medicine, University of Ulm, Ulm, Germany.

Background/aims: Mutations in the DAX1 gene cause X-linked adrenal hypoplasia congenita (AHC) classically associated with hypogonadotropic hypogonadism. Unexpectedly, precocious puberty (PP) has been reported in some cases, its mechanism remaining unclear.

Methods: We longitudinally studied a boy with AHC due to DAX1 gene mutation who developed peripheral PP at age 4. Read More

View Article
December 2018

Six-year outcome for children with ODD or CD treated with the coping power program.

Psychiatry Res 2018 Dec 4;271:454-458. Epub 2018 Dec 4.

The University of Alabama, Tuscaloosa, AL USA.

Children with severe aggressive behavioral problems are one of the groups most frequently referred to mental health clinics, and they engage in behaviors that put them at risk for substance use problems and a host of other negative outcomes. The present study aimed to assess the long-term outcome (six-year follow up) of the Coping Power Program delivered in a mental health hospital for children with behavioral disorders. We recruited one hundred and twenty children (mean age = 9. Read More

View Article
December 2018

Patterns of obsessive-compulsive symptoms and social functioning in schizophrenia; a replication study.

Psychiatry Res 2018 Dec 3;271:421-427. Epub 2018 Dec 3.

Maastricht University Medical Center, Department of Psychiatry and Neuropsychology, School for Mental Health and Neuroscience, Maastricht, the Netherlands; KU Leuven, Department of Neuroscience, Research Group Psychiatry, Leuven, Belgium.

Research has found that Obsessive Compulsive Symptoms (OCS) in schizophrenia are associated with either more or less negative symptoms and either better or poorer cognitive functioning. In order to explain these contradictory results, (Lysaker et al., 2004), performed a cluster analysis resulting in 2 OCS positive (OCSpos) clusters, one with higher functioning (HF) and one with poorer functioning (PF) compared to 2 OCS negative (OCSneg) clusters. Read More

View Article
December 2018

Prenatal thallium exposure and poor growth in early childhood: A prospective birth cohort study.

Environ Int 2018 Dec 8;123:224-230. Epub 2018 Dec 8.

Department of Maternal, Child and Adolescent Health, School of Public Health, Anhui Medical University, Hefei, People's Republic of China; Anhui Provincial Key Laboratory of Population Health & Aristogenics, Hefei, People's Republic of China. Electronic address:

Background: Thallium (Tl) exposure remains a public health problem with potential impacts on humans. Studies have suggested that prenatal exposure to thallium may be associated with fetal growth, but no studies are known have explored its association with early childhood anthropometry.

Objective: To investigate the effects of prenatal Tl exposures on early child growth and development aged 0-2 years in a prospective birth cohort study. Read More

View Article
December 2018

Action research improves services for child sexual abuse in one Caribbean nation: An example of good practice.

Child Abuse Negl 2018 Dec 8;88:225-234. Epub 2018 Dec 8.

Institute of Gender and Development Studies, The University of the West Indies, St. Augustine, Trinidad and Tobago.

Background: Child sexual abuse (CSA) is a multi-dimensional problem. The search for best practice must consider the complexities surrounding CSA and its management in any particular society.

Objective: Data previously gathered from service providers on CSA service provision in Trinidad and Tobago identified key deficient issues in policy and practice. Read More

View Article
December 2018

Childhood maltreatment and intimate partner violence victimization: A meta-analysis.

Child Abuse Negl 2018 Dec 8;88:212-224. Epub 2018 Dec 8.

Institute of Psychology, Renmin University of China, No. 59 Zhongguancun Street, Haidian District, Beijing, 100872, China. Electronic address:

Background: Intimate partner violence (IPV) victimization is a serious public health problem in the world. It is imperative to examine risk factors for IPV victimization.

Objective: This meta-analysis aimed to explore the relationship between childhood maltreatment (CM) and IPV victimization and investigate the moderating effects of gender and marital status. Read More

View Article
December 2018

Abuse disclosures of youth with problem sexualized behaviors and trauma symptomology.

Child Abuse Negl 2018 Dec 8;88:201-211. Epub 2018 Dec 8.

Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States; The Ohio State University College of Medicine, Department of Pediatrics, Nationwide Children's Hospital, 700 Children's Drive, Columbus, OH 43205, United States. Electronic address:

Background: The majority of youth with problem sexualized behaviors (PSB) have substantiated experiences of abuse or exposures to violence (Silovsky & Niec, 2002). Little is known about specific abuse experiences that may differentiate youth with PSB from those without. Few studies have examined the types of abuse associated with post-traumatic stress symptomology. Read More

View Article
December 2018
1 Read

Disentangling the effect of out-of-home care on child mental health.

Child Abuse Negl 2018 Dec 8;88:189-200. Epub 2018 Dec 8.

Department of Neuroscience, Psychology and Behaviour, University of Leicester, Leicester, LE1 7RH, England, United Kingdom. Electronic address:

Background: Children in out-of-home care are consistently found to have poor mental health compared to children in the general population. However, UK research has so far failed to disentangle the impact of the care system on children's mental health outcomes from the effects of the adverse circumstances that led to their admission to care.

Objective: This research investigated the association between care placement and the presence of child mental health problems after controlling for children's pre-care experiences. Read More

View Article
December 2018

Children engage in competitive altruism.

J Exp Child Psychol 2018 Dec 8;179:176-189. Epub 2018 Dec 8.

Department of Psychology and Neuroscience, Duke University, Durham, NC 27708, USA.

Humans cultivate their reputations as good cooperators, sometimes even competing with group mates, to appear most cooperative to individuals during the process of selecting partners. To investigate the ontogenetic origins of such "competitive altruism," we presented 5- and 8-year-old children with a dyadic sharing game in which both children simultaneously decided how many rewards to share with each other. The children were either observed by a third-person peer or not. Read More

View Article
December 2018

Experiencing regret about a choice helps children learn to delay gratification.

J Exp Child Psychol 2018 Dec 8;179:162-175. Epub 2018 Dec 8.

School of Psychology, Queen's University Belfast, Belfast BT7 1NN, Northern Ireland, UK.

Children (6- and 7-year-olds) decided whether to wait for a short delay to win a prize or for a longer period to win a different prize. Those who chose to take their prize after a short delay won two candies but were shown that they would have won four candies if they had waited longer. We measured whether children regretted their choice not to wait. Read More

View Article
December 2018
1 Read

Parental and family predictors of fruits and vegetables in elementary school Children's home-packed lunches across a school week.

Appetite 2018 Dec 8. Epub 2018 Dec 8.

Department of Human Ecology, University of California, Davis 1309 Hart Hall, One Shields Avenue, Davis, CA, 95616, USA. Electronic address:

Home-packed lunches have been found to be of lower nutritional quality than school-bought lunches, yet little is known about family-based factors associated with lunch packing. The current exploratory study examines parental and family predictors of fruits and vegetables packed in lunches, hypothesizing parents' nutrition knowledge and authoritative parenting as well as children's involvement in lunch decisions would relate to packing more fruits and vegetables, while financial difficulties would relate to packing fewer. Ninety parent-child dyads from 4th-6th grade participated for 5 consecutive school days. Read More

View Article
December 2018

Cross-border and domestic surrogacy in the UK context: an exploration of practical and legal decision-making.

Hum Fertil (Camb) 2018 Dec 11:1-12. Epub 2018 Dec 11.

b NGA Law and Brilliant Beginnings , London , UK.

This study aimed to explore UK intending parent's reasons for cross-border and domestic surrogacy, their preparations for the birth and the practical and legal challenges faced after the birth. An online survey was completed by 203 participants, of which 132 had a child born through surrogacy, 33 were in the process of surrogacy and 38 were planning a surrogacy arrangement. The most common reason for pursuing surrogacy in the UK was wanting a relationship with the surrogate (43%; n = 17) and for conducting surrogacy in the USA was because of a better legal framework (97%; n = 60). Read More

View Article
December 2018

Validation of the albumin-indocyanine green evaluation model in patients with resected hepatocellular carcinoma and comparison with the albumin-bilirubin score.

J Hepatobiliary Pancreat Sci 2018 Dec 8. Epub 2018 Dec 8.

Department of General and Oncological Surgery, Mauriziano Hospital, Turin, Italy.

Background: The albumin-indocyanine green evaluation (ALICE) model based on serum albumin and indocyanine retention rate, has been shown to be an effective method for predicting postoperative outcomes in hepatocellular carcinoma patients. Aim of the study was to validate the ALICE model in a large Western cohort of patients by comparing the Albumin-Bilirubin (ALBI) score and Child-Turcotte-Pugh (CTP) score.

Methods: A total of 400 patients who underwent hepatic resection from 01/2005 to 06/2016 at 3 centers were enrolled. Read More

View Article
December 2018

Genotype and phenotype correlations for SHANK3 de novo mutations in neurodevelopmental disorders.

Am J Med Genet A 2018 Dec 9. Epub 2018 Dec 9.

Center for Medical Genetics & Hunan Provincial Key Laboratory of Medical Genetics, School of Life Sciences, Central South University, Changsha, Hunan, China.

SHANK3 has been identified as the causative gene of 22q13.3 microdeletion syndrome phenotype. De novo mutations (DNMs) of SHANK3 were subsequently identified in patients with several neurodevelopmental disorders, including autism spectrum disorders (ASDs), schizophrenia (SCZ), a Rett syndrome-like phenotype, and intellectual disability (ID). Read More

View Article
December 2018
1 Read

Members of Minority and Underserved Communities Set Priorities for Health Research.

Milbank Q 2018 Dec;96(4):675-705

Friends of Parkside.

Policy Points Engaging and involving underrepresented communities when setting research priorities could make the scientific research agenda more equitable, more just, and more responsive to their needs and values. Groups and individuals from minority and underserved communities strongly prioritized child health and mental health research, often choosing to invest at the highest possible level. Groups consisting of predominantly Native American or Arab American participants invested in culture and beliefs research at the highest level, while many groups did not select it at all. Read More

View Article
December 2018
1 Read

Clinical and echocardiography predictors of response to inhaled nitric oxide in hypoxic preterm neonates.

J Paediatr Child Health 2018 Dec 8. Epub 2018 Dec 8.

Department of Pediatrics, University of Toronto, Toronto, Ontario, Canada.

Aim: To evaluate the clinical and echocardiography modulators of treatment response in hypoxemic preterm infants exposed to inhaled nitric oxide (iNO).

Methods: In this multicentre retrospective study, clinical parameters, including oxygenation, ventilation and haemodynamics, were collected for preterm infants <36 weeks gestation before and 2 h after initiation of iNO for acute hypoxemia. Comprehensive echocardiography, performed near the time iNO initiation, was analysed by experts blind to the clinical course. Read More

View Article
December 2018

Adalimumab efficacy for venous thrombosis in typical sites in Behçet's syndrome.

Arthritis Rheumatol 2018 Dec 7. Epub 2018 Dec 7.

Department of Neurosciences, Psychology, Pharmacology and Child Health (NEUROFARBA), University of Firenze, Italy.

In our work entitled "Adalimumab-based treatment versus DMARDs for venous thrombosis in Behçet syndrome. A retrospective study of 70 patients with vascular involvement" , we showed that Adalimumab (ADA)-based regimen is more effective and rapid than disease modifying anti-rheumatic drugs (DMARDs) in inducing resolution of venous thrombosis in patients with Behçet syndrome (BS), also allowing significant reduction of steroid exposure. This article is protected by copyright. Read More

View Article
December 2018
1 Read

A meta-analysis of neurodevelopmental outcomes at 4-10 years in children born at 22-25 weeks gestation.

Acta Paediatr 2018 Dec 10. Epub 2018 Dec 10.

University of Ottawa, Faculty of Medicine, Ottawa, Canada.

Aim: To update our meta-analysis on neurodevelopmental disability rates in children born at 22-25 weeks gestation. The main outcome measure was rates of neurodevelopmental disability in survivors at age 4-10 years.

Methods: We used a peer-reviewed electronic and grey search to identify articles. Read More

View Article
December 2018

Trends and state variations in out-of-hospital births in the United States, 2004-2017.

Birth 2018 Dec 10. Epub 2018 Dec 10.

Community Health Sciences Department, Boston University School of Public Health, Boston, Massachusetts.

Background: Out-of-hospital births have been increasing in the United States, although past studies have found wide variations between states. Our purpose was to examine trends in out-of-hospital births, the risk profile of these births, and state differences in women's access to these births.

Methods: National birth certificate data from 2004 to 2017 were analyzed. Read More

View Article
December 2018

Fathers' Dosage in Community-based Programs for Low-income Fathers.

Fam Process 2018 Dec 10. Epub 2018 Dec 10.

Center for Policy Research, Denver, CO.

Community-based programs for low-income fathers often struggle to get fathers to attend services and activities. This paper reviews the literature examining approaches to measuring dosage in fatherhood programs, rates of dosage, influences on dosage, and the associations between dosage and fathers' outcomes. Studies were limited to programs that conducted randomized control trials, quasi-experimental studies, and one-group pretest/post-test designs. Read More

View Article
December 2018

The importance of olfaction in neurodisability.

Authors:
Bernard Dan

Dev Med Child Neurol 2019 Jan;61(1)

View Article
January 2019

Neonatal neurology: bridging the gap.

Authors:
Brigitte Vollmer

Dev Med Child Neurol 2019 Jan;61(1)

Clinical Neurosciences, Faculty of Medicine, University of Southampton, Southampton, UK.

View Article
January 2019

Mothering under political violence: Post-traumatic symptoms, observed maternal parenting practices and child externalising behaviour.

Int J Psychol 2018 Dec 10. Epub 2018 Dec 10.

Bar-Ilan University, Ramat-Gan, Israel.

Using the family stress model as our conceptual framework, we explored whether observed maternal parenting practices (positive and coercive) account for the associations between mothers' post-traumatic stress symptoms and children's externalising behaviours. Mothers' self-reported post-traumatic stress symptoms, observed maternal practices, and reports of children's externalising behaviour were collected from 123 Israeli mothers and their children, who were exposed to ongoing rocket attacks in southern Israel. A structural equation model revealed that mothers' post-traumatic stress symptoms were linked with greater maternal coercive parenting practices, which in turn were associated with more externalising behaviours in children. Read More

View Article
December 2018

Relative Cost Effectiveness of In-Person and Internet Interventions for Relationship Distress.

Fam Process 2018 Dec 10. Epub 2018 Dec 10.

Department of Psychology, University of Miami, Coral Gables, FL.

While the efficacy of couple therapy has been repeatedly demonstrated, most distressed couples do not seek treatment. To improve reach and overcome barriers to therapy, Integrative Behavioral Couple Therapy (IBCT) was translated into a web-based program, OurRelationship (OR). While both IBCT and OR have been shown to improve relationship and individual functioning, the goal of the present study was to compare the relative cost effectiveness of these two treatment modalities. Read More

View Article
December 2018

Magnetic resonance imaging in enterovirus-71, myelin oligodendrocyte glycoprotein antibody, aquaporin-4 antibody, and multiple sclerosis-associated myelitis in children.

Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.

Neuroimmunology Group, Institute for Neuroscience and Muscle Research, The Kids Research Institute, Children's Hospital at Westmead, Sydney Medical School, University of Sydney, Sydney, New South Wales, Australia.

Aim: We used magnetic resonance imaging (MRI) to compare the neuroimaging of children with their first episode of clinical enterovirus 71-associated transverse myelitis (EV71-TM), myelin oligodendrocyte glycoprotein antibody positive transverse myelitis (MOG-TM), aquaporin-4 antibody positive transverse myelitis (AQP4-TM), transverse myelitis in multiple sclerosis (MS-TM), and unclassified transverse myelitis (UNC-TM).

Method: We performed a retrospective blinded radiological assessment and compared the neuroimaging of 52 children (32 females, 20 males; mean age 9y 8mo, SD 5y 5mo, range 5mo-17y) presenting with their first episode of myelitis caused by EV71-TM (n=11), MOG-TM (n=10), AQP4-TM (n=9), MS-TM (n=13), and UNC-TM (n=9).

Results: In the EV71-TM group, lesions were distributed throughout the cord and enhancement of nerve roots (ventral and dorsal) was common. Read More

View Article
December 2018

Delivery of Preventive Oral Health Services by Rurality: A Cross-Sectional Analysis.

J Rural Health 2018 Dec 7. Epub 2018 Dec 7.

RAND Corporation, Pittsburgh, Pennsylvania.

Purpose: Integrating oral health care into primary care has been promoted as a strategy to increase delivery of preventive oral health services (POHS) to young children, particularly in rural areas where few dentists practice. Using a multistate sample of Medicaid claims, we examined a child's odds of receiving POHS in a medical office by county rurality.

Methods: We used 2012-2014 Medicaid Analytic extract claims data for 6,275,456 children younger than 6 years in 39 states that allowed Medicaid payment for POHS in medical offices. Read More

View Article
December 2018

A review of interventions supporting parent's psychological well-being after a child's intensive care unit discharge.

Nurs Crit Care 2018 Dec 10. Epub 2018 Dec 10.

School of Health and Social Care, London South Bank University, London, UK.

Background: Having a child admitted to a paediatric intensive care unit (PICU) is a highly stressful experience, and post-traumatic stress among parents is well documented. How best to support these parents is currently unclear.

Aim: To review research on interventions to support the psychological well-being of parents after their child's discharge from paediatric intensive care. Read More

View Article
December 2018

Helping young people with cerebral palsy in pain.

Authors:
Paul Eunson

Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.

Royal Hospital for Sick Children - Paediatric Neurosciences, Edinburgh, UK.

View Article
December 2018

Prenatal diagnosis of antenatal midgut volvulus: Specific ultrasound features.

Prenat Diagn 2018 Dec 9. Epub 2018 Dec 9.

Department of Pediatric Imaging, CHU Montpellier, Montpellier, France.

Objective: To assess specific, direct, and indirect prenatal ultrasound features in cases of fetal midgut volvulus.

Methods: Retrospective case series of neonatal volvulus, based on postnatal and prenatal imaging findings that occurred from 2006-2017. Prenatal and postnatal signs including the specific "whirlpool sign" were computed. Read More

View Article
December 2018

Parenting behaviour and executive function in children with Down syndrome.

J Intellect Disabil Res 2018 Dec 10. Epub 2018 Dec 10.

Human Development and Family Studies, Colorado State University, Fort Collins, CO, USA.

Background: Parenting behaviours influence many domains of child development, and recent work has demonstrated the specific effects of parenting on the development of executive function (EF) abilities. The relationship between parent-child interaction patterns and EF has been examined in typically developing (TD) children but has not yet been examined in dyads where the child has a diagnosis of Down syndrome (DS).

Method: The current study examines the differences in patterns of parenting behaviours between DS dyads and dyads with TD children equated on nonverbal mental age. Read More

View Article
December 2018

Robust kidney perfusion mapping in pediatric chronic kidney disease using single-shot 3D-GRASE ASL with optimized retrospective motion correction.

Magn Reson Med 2018 Dec 7. Epub 2018 Dec 7.

Department of Brain Repair and Rehabilitation, University College London Queen Square Institute of Neurology, Queen Square, London, United Kingdom.

Purpose: To develop a robust renal arterial spin labeling (ASL) acquisition and processing strategy for mapping renal blood flow (RBF) in a pediatric cohort with severe kidney disease.

Methods: A single-shot background-suppressed 3D gradient and spin-echo (GRASE) flow-sensitive alternating inversion recovery (FAIR) ASL acquisition method was used to perform 2 studies. First, an evaluation of the feasibility of single-shot 3D-GRASE and retrospective noise reduction methods was performed in healthy volunteers. Read More

View Article
December 2018

Intellectual, adaptive and behavioural characteristics in four patients with 18p deletion syndrome.

J Intellect Disabil Res 2018 Dec 9. Epub 2018 Dec 9.

Genetics Division, Department of Morphology and Genetics, Universidade Federal de São Paulo, São Paulo, Brazil.

Background: The association of behavioural phenotype assessment with cytogenomic characterisation may provide a better comprehension of genotype-phenotype correlations in syndromes caused by chromosomal abnormalities, such as 18p deletion syndrome.

Method: We report on four Brazilian patients with 18p deletion syndrome characterised by cytogenomic techniques and detailed neuropsychological evaluation. Intellectual, adaptive and behavioural characteristics were assessed through the Wechsler's Scales, the Vineland-II Scale and the Child Behaviour Checklist, respectively. Read More

View Article
December 2018
1 Read

Mentoring beginning immigrant teachers: How culture may impact the message.

Int J Psychol 2018 Dec 10. Epub 2018 Dec 10.

Independent Consultant, San Rafael, CA, USA.

Beginning immigrant teachers may experience cross-cultural conflicts because their home cultures may differ in important ways from U.S. school culture. Read More

View Article
December 2018
1 Read

Family-provider consensus outcomes for children with medical complexity.

Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.

The Hospital for Sick Children, Toronto, Ontario, Canada.

Aim: To describe the process of obtaining consensus of outcome priorities between families of children with medical complexity (CMC) and their healthcare providers (HCPs) for the purpose of evaluating changes to service delivery.

Method: The consensus of outcomes involved surveying families of CMC and HCPs and an in-person consensus meeting. Priorities were obtained from the survey using a stratified ranking approach ensuring equal representation among unequally sized subgroups. Read More

View Article
December 2018

Detection of extracellular vesicles in the mouse vaginal fluid: Their delivery of sperm proteins that stimulate capacitation and modulate fertility.

J Cell Physiol 2018 Dec 7. Epub 2018 Dec 7.

Department of Biological Sciences, University of Delaware, Newark, Delaware.

Extracellular vesicles (EVs) were isolated by ultracentrifugation of vaginal luminal fluid (VLF) from superovulated mice and identified for the first time using transmission electron microscopy. Characterized by size and biochemical markers (CD9 and HSC70), EVs were shown to be both microvesicular and exosomal and were dubbed as "Vaginosomes" (VGS). Vaginal cross-sections were analyzed to visualize EVs in situ: EVs were present in the lumen and also embedded between squamous epithelial and keratinized cells, consistent with their endogenous origin. Read More

View Article
December 2018

Encouraging trends in the prevalence of cerebral palsy: available to all?

Authors:
Maureen S Durkin

Dev Med Child Neurol 2018 Dec 10. Epub 2018 Dec 10.

Department of Population Health Sciences and Pediatrics, University of Wisconsin School of Medicine and Public Health, Madison, WI, USA.

View Article
December 2018

The array of clinical phenotypes of males with mutations in Methyl-CpG binding protein 2.

Am J Med Genet B Neuropsychiatr Genet 2018 Dec 7. Epub 2018 Dec 7.

University of Alabama at Birmingham, Birmingham, Alabama.

Mutations in the X-linked gene MECP2 are associated with a severe neurodevelopmental disorder, Rett syndrome (RTT), primarily in girls. It had been suspected that mutations in Methyl-CpG-binding protein 2 (MECP2) led to embryonic lethality in males, however such males have been reported. To enhance understanding of the phenotypic spectrum present in these individuals, we identified 30 males with MECP2 mutations in the RTT Natural History Study databases. Read More

View Article
December 2018
1 Read

Body mass index and parasympathetic nervous system reactivity and recovery following graded exercise.

Am J Hum Biol 2018 Dec 10:e23208. Epub 2018 Dec 10.

Department of Psychology, The Ohio State University, Columbus, Ohio.

Objectives: The present study sought to expand upon prior investigations examining patterns of vagally mediated heart rate variability (vmHRV) and perceived exertion as a function of body mass index (BMI) in response to and recovery from exercise.

Methods: Participants underwent a resting (baseline) period, followed by a graded exercise protocol on an ergometer with ascending difficulty stages, and finally another resting (recovery) period. Individuals were stratified into three BMI groups: low, moderate, and high. Read More

View Article
December 2018

Previously uncharacterized amino acid residues in histone H3 and H4 mutants with roles in DNA damage repair response and cellular aging.

FEBS J 2018 Dec 7. Epub 2018 Dec 7.

Laboratory of Chromatin Biology, Department of Biological Sciences, Indian Institute of Science Education and Research, Bhopal- 462023, India.

Chromatin regulates gene expression and genome maintenance, and consists of histones and other components. The post translational modification of histones plays a key role in maintaining the structure and function of chromatin under different pathophysiological stress conditions. Here, we investigate the functions of previously unexplored amino acid residues in histones H3 and H4. Read More

View Article
December 2018
1 Read

How does 'Becoming Breastfeeding Friendly' work? A Program Impact Pathways analysis.

Matern Child Nutr 2018 Dec 7:e12766. Epub 2018 Dec 7.

Yale School of Public Health, New Haven, CT, USA.

Becoming Breastfeeding Friendly (BBF) is an initiative designed to track country readiness and progress to effectively scale up breastfeeding programs. BBF includes a policy toolbox that has three components: the Becoming Breastfeeding Friendly Index (BBFI), case studies, and a 5-meeting process. Mapping pathways of how BBF was implemented and utilized enables contextually grounded interpretation of its impact on breastfeeding outcomes. Read More

View Article
December 2018
1 Read

Maternal Perinatal and Concurrent Anxiety and Mental Health Problems in Early Childhood: A Sibling-Comparison Study.

Child Dev 2018 Dec 11. Epub 2018 Dec 11.

Norwegian Institute of Public Health and University of Oslo.

Do associations between maternal anxiety symptoms and offspring mental health remain after comparing differentially exposed siblings? Participants were 17,724 offspring siblings and 11,553 mothers from the Norwegian Mother and Child Cohort study. Mothers reported anxiety and depressive symptoms at 30 weeks' gestation, and 0.5, 1. Read More

View Article
December 2018

Trans-radial closure of coronary artery fistulae using Amplatzer vascular plug IV: A case series.

Catheter Cardiovasc Interv 2018 Dec 7. Epub 2018 Dec 7.

Interventional Cardiology Unit, Ospedale Papa Giovanni XXIII, Bergamo, Italy.

Background: Trans-catheter closure of coronary artery fistulae (CAF) has become a successful alternative to cardiac surgery with excellent results and acceptable low rate of complications. Different techniques and devices are available to treat the extreme anatomical variability of CAF.

Aim: We retrospectively describe our case series of five patients trans-radially treated using an Amplatzer vascular plug IV (AVP-IV) with telescoping catheter technique. Read More

View Article
December 2018

Multiple osteolytic lesions on the skull of a girl with Mendelian susceptibility to mycobacterial disease.

Pediatr Int 2018 Nov;60(11):1043-1044

Division of Infectious Diseases, Department of Medical Subspecialties, National Center for Child Health and Development, Setagaya, Tokyo, Japan.

View Article
November 2018

A survey demonstrates limited palliative care structures in paediatric nephrology from the perspective of a multidisciplinary healthcare team.

Acta Paediatr 2018 Dec 11. Epub 2018 Dec 11.

Department of Paediatric Gastroenterology, Nephrology and Metabolic Diseases, Charité - Universitätsmedizin Berlin, Germany.

Aim: Children and adolescents with end stage renal disease face a high morbidity and mortality. Palliative care provides a multidisciplinary approach to reduce disease burden and improve quality of life. This study evaluated concepts and current structures of palliative care from the perspective of a multidisciplinary paediatric nephrology team including physicians, nurses and psychosocial health professionals. Read More

View Article
December 2018

Cryptococcus gattii infection complicated by immune reconstitution inflammatory syndrome in three apparently immunocompetent children.

J Paediatr Child Health 2018 Dec 8. Epub 2018 Dec 8.

Department of Paediatrics, Royal Darwin Hospital, Darwin, Northern Territory, Australia.

Background: Paediatric Cryptococcus gattii disease is rare, with only two previous cases recorded in the Northern Territory (NT) over the last 54 years. Immune reconstitution inflammatory syndrome (IRIS) is a recognised complication of C. gattii infection, even in the absence of an identified immunodeficiency syndrome; however, limited paediatric data exist. Read More

View Article
December 2018
1 Read

Understanding the bereavement experience of grandparents following the death of a grandchild from a life-limiting condition: a meta-ethnography.

J Adv Nurs 2018 Dec 10. Epub 2018 Dec 10.

International Observatory on End of Life Care, Lancaster University, Furness Building, Lancaster, LA1 4YG, UK.

Aim: To increase understanding of grandparental grief following the death of a grandchild from a life-limiting condition.

Design: META-ETHNOGRAPHY: DATA SOURCES: Academic Search Complete (2015, updated 2018), CINHAL, Embase, psycINFO, PubMed and Web of Science, supplemented by manual search strategies.

Review Methods: Studies were appraised and synthesised using the principles of meta-ethnography. Read More

View Article
December 2018
1 Read

Humoral immunodeficiencies: conferred risk of infections and benefits of immunoglobulin replacement therapy.

Transfusion 2018 Dec;58 Suppl 3:3056-3064

Division of Clinical Immunology, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York.

Primary immunodeficiency (PID) diseases result from genetic defects of the immune system that increase a patient's susceptibility to infections. The types of infections that occur in patients with PID diseases are dictated largely by the nature of the immunodeficiency, which can be defined by dysfunction of cellular or humoral defenses. An increasing number of PID diseases, including those with both cellular and humoral defects, have antibody deficiency as a major feature, and as a result can benefit from immunoglobulin replacement therapy. Read More

View Article
December 2018
  • Page 1 of 41896