2,126,145 results match your criteria Child & Family Behavior Therapy[Journal]


Placental DNA methylation levels at CYP2E1 and IRS2 are associated with child outcome in a prospective autism study.

Hum Mol Genet 2019 Apr 22. Epub 2019 Apr 22.

Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA.

DNA methylation acts at the interface of genetic and environmental factors relevant for autism spectrum disorder (ASD). Placenta, normally discarded at birth, is a potentially rich source of DNA methylation patterns predictive of ASD in the child. Here, we performed whole methylome analyses of placentas from a prospective study MARBLES (Markers of Autism Risk in Babies-Learning Early Signs) of high-risk pregnancies. Read More

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http://dx.doi.org/10.1093/hmg/ddz084DOI Listing

Targeted Knock-In Mice with a Human Mutation in GRTH/DDX25 Reveals the Essential Role of Phosphorylated GRTH in Spermatid Development during Spermatogenesis.

Hum Mol Genet 2019 Apr 22. Epub 2019 Apr 22.

Section on Molecular Endocrinology, Division of Developmental Biology, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.

Gonadotropin-regulated testicular RNA helicase (GRTH/DDX25) is a testis specific member of the DEAD-box family of RNA helicases expressed in meiotic and haploid germ cells which plays an essential role in spermatogenesis. There are two species of GRTH the 56 kDa non-phospho and 61 kDa phospho forms. Our early studies revealed a missense mutation (R242H) of GRTH in azoospermic men that when expressed in COS1-cells lack the phospho-form of GRTH. Read More

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https://academic.oup.com/hmg/advance-article/doi/10.1093/hmg
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http://dx.doi.org/10.1093/hmg/ddz079DOI Listing
April 2019
1 Read

Association between child marriage and utilization of maternal health care services in India: Evidence from a nationally representative cross-sectional survey.

Midwifery 2019 Apr 18;75:66-71. Epub 2019 Apr 18.

Department of Geography, University of Gour Banga, Malda 732103, West Bengal, India.

Objective: In an effort to improve utilization of maternal health care services, age at marriage of girls has gain very little attention by the policy maker and programmer. Studies have indicated that child marriage has serious negative consequences on maternal health. Moreover, there is a paucity of research on explaining the links between child marriage and maternal health care utilization. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02666138193009
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http://dx.doi.org/10.1016/j.midw.2019.04.007DOI Listing
April 2019
1 Read

The risk of malignancy in uterine polyps: A systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol 2019 Apr 15;237:48-56. Epub 2019 Apr 15.

Department of Woman, Newborn and Child, Fondazione Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Clinical Sciences and Community Health, Università degli studi di Milano, Milan, Italy. Electronic address:

Background: Endometrial polyps are a common condition. The risk of malignancy has often led to an overtreatment with high health care costs and huge psychological distress.

Objective: We conducted a systematic review and a meta-analysis in order to estimate the prevalence of premalignant and malignant lesions in women undergoing hysteroscopic polypectomy. Read More

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http://dx.doi.org/10.1016/j.ejogrb.2019.04.009DOI Listing

Impact of maternal depression trajectories on offspring socioemotional competences at age 11: 2004 Pelotas Birth Cohort.

J Affect Disord 2019 Mar 22;253:8-17. Epub 2019 Mar 22.

Departamento de Medicina Preventiva, Faculdade de Medicina FMUSP, Universidade de Sao Paulo, Av. Dr. Arnaldo, 455, 2nd floor, Sao Paulo, SP, CEP 01246-903, Brazil; Postgraduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

Background: Maternal depression is associated with impairments in child behavioural and emotional development, although the effect of exposure to maternal depression until adolescence is underexplored in most studies. This longitudinal study examined the association between maternal depressive symptoms trajectories and offspring socioemotional competences at age 11.

Methods: We included 3,437 11-year-old adolescents from the 2004 Pelotas Birth Cohort Study. Read More

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http://dx.doi.org/10.1016/j.jad.2019.03.072DOI Listing

Intelligence and memory outcomes within 10 years of childhood convulsive status epilepticus.

Epilepsy Behav 2019 Apr 18;95:18-25. Epub 2019 Apr 18.

Muir Maxwell Epilepsy Centre, University of Edinburgh, Edinburgh, UK.

Long-term intelligence and memory outcomes of children post convulsive status epilepticus (CSE) have not been systematically investigated despite evidence of short-term impairments in CSE. The present study aimed to describe intelligence and memory outcomes in children within 10 years of CSE and identify potential risk factors for adverse outcomes. In this cohort study, children originally identified by the population-based North London Convulsive Status Epilepticus in Childhood Surveillance Study (NLSTEPSS) were prospectively recruited between July 2009 and February 2013 and invited for neuropsychological assessments and magnetic resonance imaging (MRI) scans. Read More

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http://dx.doi.org/10.1016/j.yebeh.2019.03.039DOI Listing

Abdominal Pain in Children Develops With Age and Increases With Psychosocial Factors.

Clin Gastroenterol Hepatol 2019 Apr 19. Epub 2019 Apr 19.

Div of Pediatrics, Dept of Clinical and Experimental Medicine, Linköping university SE 58185 Linköping, Sweden; Crown Princess Victoria Children´s Hospital, Region Östergötland, Linköping, Sweden.

Background & Aims: Functional gastrointestinal disorders are highly prevalent, cause significant suffering, and are costly to society. Pain is a central feature of 2 of the most common functional gastrointestinal disorders-irritable bowel syndrome and functional dyspepsia. Although these disorders have been well studied in adults, their etiology is poorly understood. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S15423565193042
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http://dx.doi.org/10.1016/j.cgh.2019.04.036DOI Listing
April 2019
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Two paternal mosaicism of mutation in ELANE causing severe congenital neutropenia exhibit normal neutrophil morphology and ROS production.

Clin Immunol 2019 Apr 19. Epub 2019 Apr 19.

Chong Qing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Division of Immunology, Children's Hospital of Chongqing Medical University, Chongqing 400014, China; Ministry of Education Key Laboratory of Child Development and Disorders, Key Laboratory of Pediatrics in Chongqing, Chongqing International Science and Technology Cooperation Center for Child Development and Disorders, Children's Hospital of Chongqing Medical University, Chongqing 400014, China. Electronic address:

Severe congenital neutropenia caused by ELANE gene mutation is a rare disease. To date, only four families were reported with mosaicism. Here we examined the morphology and function of granulocytes isolated from two patients and their mosaic fathers. Read More

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http://dx.doi.org/10.1016/j.clim.2019.04.008DOI Listing

A Learning Loop Model of Collaborative Decision Making in Chronic Illness.

Acad Pediatr 2019 Apr 19. Epub 2019 Apr 19.

Center for Community Health Integration, Department of Family Medicine & Community Health, Department of Population & Quantitative Health Sciences, Department of Sociology, Case Western Reserve University, Cleveland, Ohio 44106. Electronic address:

Shared decision-making is a core attribute of quality healthcare that has proved challenging to implement and assess in pediatric practice. Current models of shared decision-making are limited, including their capacity: to incorporate multiple stakeholders; to integrate downstream effects of subacute or minor decisions; and to account for the context(s) in which such decisions are being made and enacted. Based on a review of literature from organizational psychology, cognitive sciences, business, and medicine, we propose an iterative decision-making model of care planning, and identify targets at several levels of influence warranting measurement in future studies. Read More

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http://dx.doi.org/10.1016/j.acap.2019.04.006DOI Listing

Psychiatric Symptoms and Disorders in Extremely Preterm Young Adults at 19 Years of Age and Longitudinal Findings From Middle Childhood.

J Am Acad Child Adolesc Psychiatry 2019 Apr 19. Epub 2019 Apr 19.

Institute for Women's Health, University College London, UK.

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http://dx.doi.org/10.1016/j.jaac.2019.02.020DOI Listing

Improved Mortality Associated with the Use of Extracorporeal Membrane Oxygenation.

Ann Thorac Surg 2019 Apr 19. Epub 2019 Apr 19.

Cardiothoracic Surgery, University of Colorado Denver, Aurora, CO, United States.

Background: Our objective was to evaluate the association of bridge to transplant (BTT) extracorporeal membrane oxygenation (ECMO) on survival after lung transplantation (LTx) and determine the degree to which transplant center volume affects this relationship.

Methods: Using the United Network for Organ Sharing database, we performed a retrospective cohort study evaluating the survival of patients undergoing LTx between 2005 and 2017. Based on previous literature, LTx centers were classified into 3 groups using their average annual LTx volume over the preceding 5 years; <25, 25-49, and >50. Read More

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http://dx.doi.org/10.1016/j.athoracsur.2019.03.057DOI Listing

Can simple and low-cost motor function assessments help in the diagnostic suspicion of Duchenne muscular dystrophy?

J Pediatr (Rio J) 2019 Apr 19. Epub 2019 Apr 19.

Universidade Federal do Rio de Janeiro (UFRJ), Departamento de Pediatria, Genética Clínica, Rio de Janeiro, RJ, Brazil.

Background: Duchenne muscular dystrophy, an X-linked genetic disease, leads to progressive muscle weakness mainly in the lower limbs. Motor function tests help to monitor disease progression. Can low-cost, simple assessments help in the diagnostic suspicion of Duchenne muscular dystrophy? The authors aim to define the sensitivity of time to rise from the floor, time to walk 10meters (10MWT), and time to run 10meters (10MRT), evaluating them as eventual diagnostic screening tools. Read More

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http://dx.doi.org/10.1016/j.jped.2019.02.003DOI Listing

Urotherapy in the treatment of children and adolescents with bladder and bowel dysfunction: a systematic review.

J Pediatr (Rio J) 2019 Apr 19. Epub 2019 Apr 19.

Universidade de Brasília (UnB), Departamento de Enfermagem, Brasília, DF, Brazil; Society for Pediatric Urology (SPU), United States; McGill University, Ingram School of Nursing, Quebec, Canada; Shriners Hospital for Children, Quebec, Canada.

Objective: To identify and describe the protocols and clinical outcomes of urotherapy interventions in children and adolescents with bladder bowel dysfunction.

Method: Systematic review carried out in June 2018 on MEDLINE/PubMed, CINAHL, EMBASE, SciELO, Cochrane, and PsycInfo databases. Clinical trials and quasi-experimental studies carried out in the last ten years in children and/or adolescents with bladder and bowel symptoms and application of at least one component of urotherapy were included. Read More

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http://dx.doi.org/10.1016/j.jped.2019.02.007DOI Listing

Asthma mortality in children and adolescents of Brazil over a 20-year period.

J Pediatr (Rio J) 2019 Apr 19. Epub 2019 Apr 19.

Universidade Federal de Minas Gerais (UFMG), Hospital das Clínicas, Belo Horizonte, MG, Brazil.

Objective: To evaluate the number of asthma deaths and the temporal trend of the asthma-specific mortality rate in children and adolescents up to 19 years of age in Brazil.

Methods: This is an ecological time-series study of asthma deaths reported in Brazil, in the population up to 19 years of age, between 1996 and 2015. The specific asthma mortality rate and its temporal trend were analyzed. Read More

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http://dx.doi.org/10.1016/j.jped.2019.02.006DOI Listing

Neonatal screening tests in Brazil: prevalence rates and regional and socioeconomic inequalities.

J Pediatr (Rio J) 2019 Apr 19. Epub 2019 Apr 19.

Universidade Federal de Santa Catarina (UFSC), Departamento de Saúde Pública, Florianópolis, SC, Brazil. Electronic address:

Objective: To identify the prevalence and associated factors with the performance of the Guthrie test, hearing, and red reflex screening tests in Brazil.

Methods: This was a population-based, cross-sectional study that analyzed data on 5231 children under 2 years of age participating in the National Health Survey of 2013. The study described the prevalence and confidence intervals (95% CI) of the three neonatal screening tests performed, in any period, and their association with the country's regions, skin color/ethnicity, private health insurance, and per capita household income. Read More

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http://dx.doi.org/10.1016/j.jped.2019.02.008DOI Listing

The development of a theory-based eHealth app prototype to promote oral health during prenatal care visits.

Transl Behav Med 2019 Apr 22. Epub 2019 Apr 22.

Nudgently, LLC, Eugene, OR, USA.

Poor maternal oral health during pregnancy is associated with adverse maternal and child outcomes, including preterm birth and early childhood caries. Subsequently, professional associations have developed prenatal oral health guidelines, but significant gaps exist in implementing guidelines into clinical practice. The purpose of this study was to develop and test the usability of an innovative, theory-driven, eHealth application ("app") to facilitate prenatal providers' (nurse practitioners and midwives) implementation of oral health promotion during prenatal care visits. Read More

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http://dx.doi.org/10.1093/tbm/ibz047DOI Listing

Genetic and phenotypic characteristics of SCN1A-related epilepsy in Chinese children.

Neuroreport 2019 Apr 19. Epub 2019 Apr 19.

Department of Neurology, Children's Hospital of Chongqing Medical University.

SCN1A gene mutations are associated with epilepsy and neurodevelopmental disorders. This study aimed to explore the genotype and phenotype spectrum of SCN1A gene related epilepsy. Epileptic patients who were treated in the Children's Hospital of Chongqing Medical University from January 2015 to July 2018 and identified as having SCN1A mutations by targeted next-generation sequencing were included. Read More

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http://dx.doi.org/10.1097/WNR.0000000000001259DOI Listing

A Survey of Nurses' Need for Care Robots in Children's Hospitals: Combining Robot-Care, Game-Care, and Edu-Care.

Comput Inform Nurs 2019 Apr 19. Epub 2019 Apr 19.

Author Affiliations: College of Nursing, Consumer Health Informatics & Communication Laboratory (Ms Jin and Dr Kim), Research Institute of Nursing Science (Dr Kim), Seoul National University, Seoul, Republic of Korea.

The purpose of this study was to investigate nurses' need for care robots in children's hospitals and to help develop care robots that can be used by combining robot-care, game-care, and edu-care. This study employed a mixed-methods design; 198 nurses were recruited for quantitative research and 12 for qualitative research. The findings were as follows. Read More

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http://dx.doi.org/10.1097/CIN.0000000000000527DOI Listing
April 2019
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Arteriopathy Influences Pediatric Ischemic Stroke Presentation, but Sickle Cell Disease Influences Stroke Management.

Stroke 2019 May;50(5):1089-1094

Departments of Pediatrics, Neurology and Neurotherapeutics, University of Texas Southwestern Medical Center at Dallas and Children's Health Dallas (M.M.D.).

Background and Purpose- Sickle cell disease (SCD) and arteriopathy are pediatric stroke risk factors that are not mutually exclusive. The relative contributions of sickled red blood cells and arteriopathy to stroke risk are unknown, resulting in unclear guidelines for primary and secondary stroke prevention when both risk factors are present. We hypothesized that despite similarities in clinical presentation and radiographic appearance of arteriopathies, stroke evaluation and management differ in children with SCD compared with those without SCD. Read More

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.022800
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http://dx.doi.org/10.1161/STROKEAHA.118.022800DOI Listing
May 2019
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Impact of Hanging Motionless in Harness on Respiratory and Blood Pressure Reflex Modulation in Mountain Climbers.

High Alt Med Biol 2019 Apr 19. Epub 2019 Apr 19.

1 School of Medicine and Surgery, University of Milano-Bicocca, Monza, Italy.

Lanfranconi, Francesca, Alessandra Ferri, Luca Pollastri, Manuela Bartesaghi, Massimiliano Novarina, Giovanni De Vito, Egidio Beretta, and Lucio Tremolizzo. Impact of hanging motionless in harness on respiratory and blood pressure reflex modulation in mountain climbers. 16:000-000, 2019. Read More

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https://www.liebertpub.com/doi/10.1089/ham.2018.0089
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http://dx.doi.org/10.1089/ham.2018.0089DOI Listing
April 2019
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Patient Satisfaction and Treatments Offered to Swedish Patients with Suspected Pediatric Acute-Onset Neuropsychiatric Syndrome and Pediatric Autoimmune Neuropsychiatric Disorders Associated with Streptococcal Infections.

J Child Adolesc Psychopharmacol 2019 Apr 19. Epub 2019 Apr 19.

1 Department of Clinical Neuroscience, Center for Psychiatry Research, Karolinska Institutet, Stockholm, Sweden.

Pediatric acute-onset neuropsychiatric syndrome (PANS) and pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) are subtypes of Obsessive-Compulsive Disorder (OCD) with suggested autoimmune etiology. Immunomodulatory treatments have been introduced as treatment options. A recent systematic review concluded that the evidence for all treatment options for PANS and PANDAS is inconclusive. Read More

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http://dx.doi.org/10.1089/cap.2018.0141DOI Listing

Pharmacological Treatment of Youth Substance Use Disorders.

J Child Adolesc Psychopharmacol 2019 Apr 22. Epub 2019 Apr 22.

Department of Psychiatry and Behavioral Sciences, Medical University of South Carolina, Charleston, South Carolina.

While the majority of youth who experiment with alcohol and drugs do not develop problematic levels of use, 5% of adolescents and 15% of young adults meet criteria for a substance use disorder (SUD). Pharmacotherapy, in combination with behavioral interventions, has the potential to increase the likelihood of successful treatment for youth struggling with SUD; however, the literature in this area is limited. To date, there are no Food and Drug Administration (FDA)-approved medications for adolescent SUD, other than buprenorphine, which has been approved down to 16 years of age for opioid use disorder. Read More

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http://dx.doi.org/10.1089/cap.2019.0009DOI Listing

Homozygous stop mutation in AHR causes autosomal recessive foveal hypoplasia and infantile nystagmus.

Brain 2019 Apr 22. Epub 2019 Apr 22.

Molecular Genetics Laboratory, Institute for Ophthalmic Research, University of Tuebingen, Tuebingen, Germany.

Herein we present a consanguineous family with three children affected by foveal hypoplasia with infantile nystagmus, following an autosomal recessive mode of inheritance. The patients showed normal electroretinography responses, no signs of albinism, and no anterior segment or brain abnormalities. Upon whole exome sequencing, we identified a homozygous mutation (c. Read More

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https://academic.oup.com/brain/advance-article/doi/10.1093/b
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http://dx.doi.org/10.1093/brain/awz098DOI Listing
April 2019
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Effect of Albuterol Premedication vs Placebo on the Occurrence of Respiratory Adverse Events in Children Undergoing Tonsillectomies: The REACT Randomized Clinical Trial.

JAMA Pediatr 2019 Apr 22. Epub 2019 Apr 22.

Telethon Kids Institute, Perth, Australia.

Importance: Tonsillectomy is a common pediatric procedure for the treatment of sleep-disordered breathing and chronic tonsillitis. Up to half of children having this procedure experience a perioperative respiratory adverse event.

Objective: To determine whether inhaled albuterol sulfate (salbutamol sulfate) premedication decreases the risk of perioperative respiratory adverse events in children undergoing anesthesia for tonsillectomy. Read More

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http://dx.doi.org/10.1001/jamapediatrics.2019.0788DOI Listing

Studying Brain Function in Children Using Magnetoencephalography.

J Vis Exp 2019 Apr 8(146). Epub 2019 Apr 8.

ARC Centre of Excellence in Cognition and its Disorders, Macquarie University; Department of Cognitive Science, Macquarie University;

Magnetoencephalography (MEG) is a non-invasive neuroimaging technique which directly measures magnetic fields produced by the electrical activity of the human brain. MEG is quiet and less likely to induce claustrophobia compared with magnetic resonance imaging (MRI). It is therefore a promising tool for investigating brain function in young children. Read More

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http://dx.doi.org/10.3791/58909DOI Listing

Damage control orthopedics applied in an 8-year-old child with life-threatening multiple injuries: A CARE-compliant case report.

Medicine (Baltimore) 2019 Apr;98(16):e15294

University Children's Hospital Basel (UKBB), Department of Pediatric Surgery, 4056 Basel.

Rationale: Damage control is a staged surgical approach to manage polytraumatized patients. The damage control approach comprises three steps. First, bleeding is controlled and fractures are stabilized temporarily; second, vital parameters are stabilized and the child is rewarmed in the intensive care unit; and third, the child is reoperated for definitive repair of injuries. Read More

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http://Insights.ovid.com/crossref?an=00005792-201904190-0005
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http://dx.doi.org/10.1097/MD.0000000000015294DOI Listing
April 2019
2 Reads

Echinococcosis in left ventricle: a case report.

Medicine (Baltimore) 2019 Apr;98(16):e15267

Department of Radiology, West China Hospital, Sichuan University, Chengdu, China.

Introduction: Echinococcosis, also called hydatid disease, is a common parasitic infection of the liver. However, echinococcus lesions rarely involve the heart, especially in children.

Patient Concerns: An 8-year-old child from grazing areas of northwest China was referred to our hospital for the complaint of inpersistent precordial chest pain and left upper quadrant pain for 3 years. Read More

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http://dx.doi.org/10.1097/MD.0000000000015267DOI Listing

Congenital Cranial Dysinnervation Disorder: An Unusual Phenotype With Multiple Cranial Neuropathies and Novel Neuroimaging Findings.

J Neuroophthalmol 2019 Apr 16. Epub 2019 Apr 16.

Section of Pediatric Neurology (MSS, SEM), Children's Hospital; Department of Pediatrics and Child Health, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; Section of Pediatric Ophthalmology (CM), Children's Hospital; Department of Ophthalmology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada; Section of Pediatric Radiology (JW), Children's Hospital; Department of Radiology, Max Rady College of Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Canada.

Congenital cranial dysinnervation disorders result from a maldevelopment of brainstem nuclei and/or cranial nerves. In some cases, specific genetic abnormalities have been identified. We expand the clinical phenotype of these disorders with the report of a 28-month-old girl who was initially evaluated for seizures and was found to have right sixth nerve palsy, small optic discs with reduced vision in her right eye. Read More

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http://dx.doi.org/10.1097/WNO.0000000000000762DOI Listing

Outcomes of Descemet-Stripping Automated Endothelial Keratoplasty in Congenital Hereditary Endothelial Dystrophy.

Eye Contact Lens 2019 Apr 15. Epub 2019 Apr 15.

Eye Research Center (M.M., A.N., K.F.), Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran; and Noor Ophthalmology Research Center (H.H.), Noor Eye Hospital, Tehran, Iran.

Objectives: To evaluate the outcomes and complications of Descemet-stripping automated endothelial keratoplasty (DSAEK) in children with congenital hereditary endothelial dystrophy (CHED).

Methods: Eighteen eyes from 10 children with CHED who underwent standard phakic DSAEK were enrolled in this retrospective interventional case series. Medical records including slit-lamp biomicroscopy, cycloplegic refraction, visual acuity, and measurements of central corneal thickness, corneal topography, and endothelial cell density were evaluated. Read More

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http://dx.doi.org/10.1097/ICL.0000000000000604DOI Listing
April 2019
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Inflammatory biomarkers in HIV-infected children hospitalized for severe malnutrition in Uganda and Zimbabwe.

AIDS 2019 Apr 16. Epub 2019 Apr 16.

MRC Clinical Trials Unit at UCL, London, UK.

Objectives: A proportion of HIV-infected children with advanced disease develop severe malnutrition soon after antiretroviral therapy (ART) initiation. We tested the hypothesis that systemic inflammation underlies the pathogenesis of severe malnutrition in HIV-infected children.

Design: Cross-sectional laboratory sub-study in 613 HIV-infected children initiating ART in Uganda and Zimbabwe. Read More

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http://dx.doi.org/10.1097/QAD.0000000000002231DOI Listing

The importance of developing relevant animal models to assess existing and new materials.

Curr Opin Urol 2019 Apr 16. Epub 2019 Apr 16.

Centre for Surgical Technologies.

Purpose Of Review: We summarize the recent literature on the use of different animal models for testing existing and new materials for treatment of pelvic organ prolapse.

Recent Findings: A wide spectrum of animal models is being used in urogynecology, both for the study of physiologic and pathophysiologic processes, training in surgical procedures, yet mainly to study the host response to implant materials. The quality of studies is variable, and procedures, read-outs, and reporting are not standardized. Read More

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http://dx.doi.org/10.1097/MOU.0000000000000625DOI Listing

Associations between Physical Activity and Chronic Pain Severity in Youth With Chronic Abdominal Pain.

Clin J Pain 2019 Apr 18. Epub 2019 Apr 18.

Children's Mercy Hospital.

Objectives: The present study aimed to: (1) better understand physical activity levels in youth with chronic abdominal pain and (2) investigate the relationship between day-level physical activity related to next day pain intensity to identify any intra-individual heterogeneity.

Methods: Seventy-one youth (M=13.34▒y, SD=2. Read More

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http://dx.doi.org/10.1097/AJP.0000000000000716DOI Listing

Fathering on Tenuous Ground: A Qualitative Meta-Synthesis on Teen Fathering.

MCN Am J Matern Child Nurs 2019 Apr 17. Epub 2019 Apr 17.

Lee SmithBattle is a Professor of Nursing, School of Nursing, Saint Louis University, Saint Louis, MO. The author can be reached via e-mail at Wisitsri Phengnum is a Doctoral Student, School of Nursing, Saint Louis University, Saint Louis, MO. Anne Winnie Shagavah is a Doctoral Candidate, School of Nursing, Saint Louis University, Saint Louis, MO. Satoko Okawa is an Associate Professor of Nursing, School of Nursing, Osaka Prefecture University, Osaka, Japan.

Background: Although teen fathers are a vulnerable group of parents, they have received far less attention than teen mothers.

Purpose: We conducted a systematic search of qualitative studies that examined their prenatal and postpartum experience to better understand teen fathers' concerns, strengths, and vulnerabilities.

Methods: We searched nine electronic databases through September 2017; 29 studies represented in 30 articles met study criteria. Read More

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http://dx.doi.org/10.1097/NMC.0000000000000536DOI Listing

Patients' and Doctors' Perceptions of a Mobile Phone-Based Consultation Service for Maternal, Neonatal, and Infant Health Care in Bangladesh: A Mixed-Methods Study.

JMIR Mhealth Uhealth 2019 Apr 22;7(4):e11842. Epub 2019 Apr 22.

National Centre for Epidemiology and Population Health, Research School of Population Health, The Australian National University, Canberra, Australia.

Background: A mobile-based consultation service, or telehealth, can be used for remote consultations with health care professionals for screening, self-care management, and referral. In rural Bangladesh, where there is high demand for scarce male and even scarcer female doctors, remote consultations may help women seeking maternal and child health care. Aponjon is a mHealth service in Bangladesh that provides weekly voice or text messages to pregnant women, new mothers, and family members on various aspects of maternal, neonatal, and infant health. Read More

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http://dx.doi.org/10.2196/11842DOI Listing
April 2019
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iCanCope PostOp: User-Centered Design of a Smartphone-Based App for Self-Management of Postoperative Pain in Children and Adolescents.

JMIR Form Res 2019 Apr 22;3(2):e12028. Epub 2019 Apr 22.

Child Health Evaluative Sciences, The Hospital for Sick Children, Toronto, ON, Canada.

Background: Moderate to severe postoperative pain in children is common. Increased pediatric day surgeries have shifted postoperative pain management predominantly to the home setting. Mobile health technology has the potential to overcome barriers to pain care by improving access to self-management resources. Read More

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http://dx.doi.org/10.2196/12028DOI Listing

Association between Medical Well-Child Visits and Dental Preventive Visits: A Big Data Report.

JDR Clin Trans Res 2019 Apr 22:2380084419841850. Epub 2019 Apr 22.

2 DentaQuest Partnership for Oral Health Advancement, Boston, MA, USA.

Objective: This study evaluated the impact of well-child visits (WCVs) on promoting preventive visits to the dentist. Effects by age, race, gender, and dental diagnosis were investigated.

Methods: Administrative claims data for 1. Read More

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http://dx.doi.org/10.1177/2380084419841850DOI Listing

The prevalence of substance use in child welfare and general population eighth graders in the United States.

Authors:
Julia M Kobulsky

Subst Use Misuse 2019 Apr 22:1-9. Epub 2019 Apr 22.

a School of Social Work College of Public Health , Temple University , Philadelphia , Pennsylvania , USA.

Background: Early substance use is an established risk factor for substance abuse and dependence.

Objective: The current study sought to examine whether child welfare-involved eighth graders have higher rates of early substance use than general population eighth graders. Data from the first National Survey of Child and Adolescent Well-Being (NSCAW) were analyzed to assess the prevalence of self-reported substance use, including alcohol, marijuana, and inhalant use in child welfare-involved eighth graders (N = 896). Read More

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https://www.tandfonline.com/doi/full/10.1080/10826084.2019.1
Publisher Site
http://dx.doi.org/10.1080/10826084.2019.1594907DOI Listing
April 2019
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The education avenue of the clinical learning environment: A pragmatic approach.

Med Teach 2019 Apr 22:1-7. Epub 2019 Apr 22.

d Formerly Accreditation Council of Graduate Medical Education , Chicago , IL , USA.

Aim: This perspective is part of a series of articles that are outcomes of a consensus conference, that seek to offer a comprehensive examination of the clinical learning environment (CLE), using different academic disciplines and areas of focus termed "avenues." The education dimensions of the CLE are discussed in detail in this perspective, along with critical linkages to the other avenues.

Methods: Using iterative presentations, discussion and small group work, in October 2018, the consensus conference participants explored the education, psychological, sociocultural, diversity and inclusion, digital and architectural aspects of the CLE. Read More

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http://dx.doi.org/10.1080/0142159X.2019.1566602DOI Listing

Midlife general psychopathology trajectories and later-life physical health in husbands and wives.

Health Psychol 2019 Apr 22. Epub 2019 Apr 22.

Department of Human Development and Family Science, University of Georgia.

Objective: General psychopathology (GPP), as reflected by dimensional symptoms of depression, anxiety, and hostility, has been shown to have a persistent influence on physical health problems. Yet, little is known about longitudinal changes in GPP and the long-term GPP- physical health process within married couples over their midlater years. This study examined the multilevel influence of GPP trajectories on husbands' and wives' physical health problems at the couple- and individual-levels over a period of 25 years. Read More

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http://dx.doi.org/10.1037/hea0000745DOI Listing
April 2019
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"How Is My Child's Asthma?" Digital Phenotype and Actionable Insights for Pediatric Asthma.

JMIR Pediatr Parent 2018 Jul-Dec;1(2). Epub 2018 Nov 30.

Department of Computer Sciene, Ohio Center of Excellence in Knowledge-enabled Computing (Kno.e.sis), Wright State University, Dayton, OH, United States.

Background: In the traditional asthma management protocol, a child meets with a clinician infrequently, once in 3 to 6 months, and is assessed using the Asthma Control Test questionnaire. This information is inadequate for timely determination of asthma control, compliance, precise diagnosis of the cause, and assessing the effectiveness of the treatment plan. The continuous monitoring and improved tracking of the child's symptoms, activities, sleep, and treatment adherence can allow precise determination of asthma triggers and a reliable assessment of medication compliance and effectiveness. Read More

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http://dx.doi.org/10.2196/11988DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469868PMC
November 2018

Gonadal Tissue Cryopreservation for a Girl With Partial Androgen Insensitivity Syndrome.

J Endocr Soc 2019 May 13;3(5):887-891. Epub 2019 Mar 13.

Department of Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.

Individuals with differences/disorders of sex development (DSD) have increased rates of infertility. For children and youth undergoing prophylactic gonadectomy for malignancy risk, our institution offers gonadal tissue cryopreservation, an experimental technique to preserve fertility cryopotential. An 11-year-old girl with partial androgen insensitivity syndrome presented for evaluation for fertility preservation in the setting of a planned bilateral gonadectomy at an outside institution. Read More

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http://dx.doi.org/10.1210/js.2019-00023DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6467392PMC

Resilience dynamics after interventions made among school children of rural Ethiopia.

Heliyon 2019 Apr 8;5(4):e01464. Epub 2019 Apr 8.

Save the Children Denmark Child Protection Advisor, Copenhagen, Denmark.

Objectives of this study are to evaluate the impact of interventions on school children resilience and well-being; assess sensitivity of resilience evaluation tools; and identify shift in resilience among children in poor rural communities of Ethiopia. Qualitative and quantitative data are collected using semi-structured Pre- and Post- Interview Analysis (PIA), child and youth resilience measure (CYRM) and mental health continuum (MHC) questionnaires among the control and intervention groups. The study identified that PIA questions were not sensitive enough to detect all child resilience indicators. Read More

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http://dx.doi.org/10.1016/j.heliyon.2019.e01464DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458468PMC

One year outcome of high-risk newborn infants discharged from the neonatal care unit of the National Maternal and Child Health Center in Cambodia.

Heliyon 2019 Apr 9;5(4):e01446. Epub 2019 Apr 9.

Bureau of International Health Cooperation, National Center for Global Health and Medicine, 1-21-1 Toyama, Shinjuku, Tokyo 162-8655, Japan.

Background: In the National Maternal and Child Health Center in Cambodia, about 7,500 newborn infants are born every year. Around 10% of them are admitted to the neonatal care unit. After recovery from the acute phase that presented neonatal care unit admissions, they are discharged even if they are very low birth weight infants, but there is no official follow-up system available after discharge. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24058440183210
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http://dx.doi.org/10.1016/j.heliyon.2019.e01446DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458445PMC
April 2019
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Aortic pulse wave velocity in children with Cushing syndrome: A window into a marker of early cardiovascular disease.

Endocrinol Diabetes Metab 2019 Apr 15;2(2):e00054. Epub 2019 Jan 15.

Section on Endocrinology and Genetics Eunice Kennedy Shriver National Institute of Child Health Bethesda Maryland.

Objective: To investigate early signs of cardiovascular arterial remodelling in paediatric patients with Cushing syndrome (CS) in comparison with normative values from healthy children.

Study Design: The metrics used to assess cardiac health were from thoracic aorta and carotid MRI. Scans were performed on 18 children with CS (mean: 12. Read More

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http://dx.doi.org/10.1002/edm2.54DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6458483PMC

Erythema multiforme in a child with Kawasaki disease.

JAAD Case Rep 2019 Apr 6;5(4):386-388. Epub 2019 Apr 6.

Department of Dermatology, University of California, Irvine, California.

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http://dx.doi.org/10.1016/j.jdcr.2019.02.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454123PMC

Widespread keratosis pilaris-like eruption in an immunocompromised child.

JAAD Case Rep 2019 Apr 5;5(4):352-354. Epub 2019 Apr 5.

Department of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah.

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http://dx.doi.org/10.1016/j.jdcr.2019.02.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6453831PMC

Pulmonary Function Testing in Pediatric Pneumonia Patients With Wheezing Younger Than 3 Years of Age.

Glob Pediatr Health 2019 9;6:2333794X19840357. Epub 2019 Apr 9.

Children's Hospital of Michigan, Detroit, MI, USA.

Wheezing symptoms are one of the risk factors in young pneumonia patients that often leads to asthma development. Infant pulmonary function test (iPFT) is potentially a useful tool to help identify and manage these high-risk pneumonia patients. To examine whether patients with wheezing symptoms are more likely to have poorer pulmonary function and treatment outcomes, and also to explore the clinical benefit of iPFT in young pneumonia patients, we conducted a retrospective analysis of 1005 pneumonia inpatients <3 years of age who had undergone iPFT testing in 2016 at Liuzhou Maternity and Child Healthcare Hospital in Guang-Xi, China. Read More

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http://journals.sagepub.com/doi/10.1177/2333794X19840357
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http://dx.doi.org/10.1177/2333794X19840357DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6457021PMC
April 2019
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Using information sources by breast cancer women treated with mastectomy.

J Educ Health Promot 2019 14;8:68. Epub 2019 Mar 14.

PhD in Information Sciences and Knowledge Studies, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Awareness of sources of information of mastectomy patients has an important role in accessibility of reliable health information sources, thus, when they get information, they can be effective in the treatment and self-care. The present study aimed to identify the sources of information used by women underwent mastectomy.

Materials And Methods: The current practical research methodology was qualitative, and research method was conventional qualitative content analysis was performed on 17 patients with breast cancer undergone mastectomy. Read More

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http://dx.doi.org/10.4103/jehp.jehp_224_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442256PMC

The presence of the child, the opportunity or a threat to marital satisfaction: A qualitative study.

J Educ Health Promot 2019 14;8:67. Epub 2019 Mar 14.

Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.

Background: The aim of this qualitative study was to explore if the presence of a child in the family was an opportunity or threat to the marital life.

Methods: In this common qualitative content analysis, semi-structured interviews with 20 participants were conducted. All of the interviews were recorded and then transcribed. Read More

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http://dx.doi.org/10.4103/jehp.jehp_250_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6442331PMC
March 2019
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Visualizing mental representations in schizophrenia patients: A reverse correlation approach.

Schizophr Res Cogn 2019 Sep 6;17:100138. Epub 2019 Apr 6.

University Medical Centre Utrecht Brain Centre, dept of Psychiatry, Utrecht, The Netherlands.

Schizophrenia patients have difficulties recognizing emotional states from faces, in particular those with negative valence, with severe consequences for daily life. What do these patients see in their minds eye, when they think of a face expressing a particular emotion or trait? The content of such mental representations can shed light into the nature of their deficits, but are usually inaccessible. For the first time, we explored the applicability of reverse correlation, which has been successfully used to visualize mental representations in healthy populations, to visualize mental representations in schizophrenia patients. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22150013183005
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http://dx.doi.org/10.1016/j.scog.2019.100138DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454059PMC
September 2019
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