2,233,010 results match your criteria Child & Youth Care Forum[Journal]


Takayasu arteritis in a patient diagnosed with acute rheumatic fever presenting with carditis: Is it a coincidental association or an aetiological relationship?

J Paediatr Child Health 2020 Jul 4. Epub 2020 Jul 4.

Faculty of Medicine, Department of Pediatric Cardiology, Eskisehir Osmangazi University, Eskisehir, Turkey.

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http://dx.doi.org/10.1111/jpc.14992DOI Listing

COVID-19 and children. From Luis Sepulveda to Madam Mim.

J Paediatr Child Health 2020 Jul 4. Epub 2020 Jul 4.

Microbiology Unit, Kingston Hospital NHS Foundation Trust, Kingston Upon Thames, UK.

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http://dx.doi.org/10.1111/jpc.15040DOI Listing

Impact of an extended postnatal home visiting programme on oral health among children in a disadvantaged area of Stockholm, Sweden.

Acta Paediatr 2020 Jul 4. Epub 2020 Jul 4.

Division of Orthodontics and Pediatric Dentistry, Department of Dental Medicine, Karolinska Institutet, Stockholm, Sweden.

Aim: To evaluate oral health outcomes and early oral health promotion of children in a Swedish, parental support programme conducted in a collaboration between Child Health Services and Social Services.

Methods: The intervention offered first-time parents six home visits from a paediatric nurse and a parental advisor with Social Services. On the fourth visit (infant age 6-8 months), parents received a toothbrush and fluoride toothpaste from non-dental staff. Read More

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http://dx.doi.org/10.1111/apa.15457DOI Listing

Debate: Mentalising remotely - The AFNCCF's adaptations to the coronavirus crisis.

Child Adolesc Ment Health 2020 Jul 5. Epub 2020 Jul 5.

Anna Freud National Centre for Children and Families, London, UK.

An overview of the work the approach taken by the Anna Freud National Centre for Children and Families in the rapid transition to remote working in response to the coronavirus lockdown. We outline some of the challenges of remote working and how we are seeking to mitigate them, informed by the over-riding principle that individual relationships and the experiences of the child, young person and family must remain the central concern. The importance of maintaining a mentalising stance in remote working is discussed. Read More

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http://dx.doi.org/10.1111/camh.12404DOI Listing

The co-occurrence between symptoms of internet gaming disorder and psychiatric disorders in childhood and adolescence: prospective relations or common causes?

J Child Psychol Psychiatry 2020 Jul 5. Epub 2020 Jul 5.

Department of Psychology, Norwegian University of Science and Technology, Trondheim, Norway.

Background: Internet gaming disorder (IGD) is highlighted as a condition for further study in the Diagnostic and Statistical Manual of Mental Disorders Fifth Edition (DSM-5). Some studies indicate that IGD appears comorbid with other psychiatric disorders. We examine concurrent and prospective links between symptoms of IGD and symptoms of common psychiatric disorders in childhood and adolescence to determine whether observed comorbidity is a result of (a) reciprocal relations or (b) common underlying causes. Read More

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http://dx.doi.org/10.1111/jcpp.13289DOI Listing

Outcomes of subsequent pregnancies following Zika virus infection: A comparative case series.

Int J Gynaecol Obstet 2020 Jul 4. Epub 2020 Jul 4.

Instituto de Pesquisa Professor Amorim Neto (IPESQ), Campina Grande, Paraiba, Brazil.

Objective: To describe eight cases of women who became pregnant after a previous pregnancy that resulted in a fetus with congenital Zika syndrome (CZS).

Methods: A prospective case series follow up study of all children of mothers that were pregnant with a fetus with CZS epidemics and delivered in a subsequent pregnancy. Head circumference at birth and abnormalities detected at neuroimaging were the primary outcomes. Read More

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http://dx.doi.org/10.1002/ijgo.13288DOI Listing

COVID-19 and child and adolescent psychiatry: an unexpected blessing for part of our population?

Eur Child Adolesc Psychiatry 2020 Jul 4. Epub 2020 Jul 4.

Department of Child and Adolescent Psychiatry, Amsterdam UMC, University of Amsterdam, Meibergdreef 5, 1105 AZ, Amsterdam, The Netherlands.

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http://dx.doi.org/10.1007/s00787-020-01578-5DOI Listing

Distinguishing selective mutism and social anxiety in children: a multi-method study.

Eur Child Adolesc Psychiatry 2020 Jul 4. Epub 2020 Jul 4.

Department of Psychology, Neuroscience and Behaviour, McMaster University, Room 130, Psychology Building, 1280 Main Street West, Hamilton, ON, L8S 4K1, Canada.

Selective mutism (SM) is an anxiety disorder in which a child fails to speak in some situations (e.g., school) despite the ability to speak in other situations (e. Read More

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http://dx.doi.org/10.1007/s00787-020-01588-3DOI Listing

Which Risk Factors for Child Maltreatment Predict Mothers' Enrollment in a Parenting Support Program?

Prev Sci 2020 Jul 4. Epub 2020 Jul 4.

Université Laval, Quebec City, Canada.

Parenting support programs are an effective means of preventing child maltreatment. However, these programs are often criticized for their limited ability to enroll and engage the parents who need them most. The present study aimed to determine which risk factors associated with child maltreatment predicted mothers' enrollment in the Triple P-Positive Parenting Program in Quebec. Read More

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http://dx.doi.org/10.1007/s11121-020-01138-yDOI Listing

Cell-based assays for the detection of MOG antibodies: a comparative study.

J Neurol 2020 Jul 4. Epub 2020 Jul 4.

Neuroimmunology Laboratory, IRCCS Mondino Foundation, Pavia, Italy.

Background: The detection of antibodies to myelin oligodendrocyte glycoprotein (MOG) is fundamental for the identification of MOG antibody-associated disorders (MOGAD), and the differential diagnosis of acquired demyelinating syndromes of the CNS, among which multiple sclerosis (MS). We compared the diagnostic performance of four cell-based assays (CBAs) for their detection.

Methods: Consecutive sera from 204 patients with 'possible MOGAD' (55), MS (112), and other neurological disorders (OND, 37) were tested for MOG-IgG with a live-CBA with anti-heavy-and-light chain secondary-antibody (LCBA-IgG), and a live-CBA for IgG (LCBA-IgG). Read More

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http://dx.doi.org/10.1007/s00415-020-10024-0DOI Listing

Lesions Over Palms and Soles - A Clue to the Re-emerging Masquerader!

Indian J Pediatr 2020 Jul 4. Epub 2020 Jul 4.

Department of Pediatric Medicine, Indira Gandhi Institute of Child Health, Bangalore, Karnataka, India.

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http://dx.doi.org/10.1007/s12098-020-03405-wDOI Listing

Associations Among Household Chaos, School Belonging and Risk Behaviors in Adolescents.

J Prim Prev 2020 Jul 4. Epub 2020 Jul 4.

Division of Child Development and Community Health, Department of Pediatrics, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA, 92093-0927, USA.

We examined the associations between adolescent risk behaviors and household chaos, and whether associations varied by adolescents' sense of school belonging. We collected data from 801 Chilean adolescents from working-class families (M age 16.2 years). Read More

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http://dx.doi.org/10.1007/s10935-020-00592-2DOI Listing

Examining the Role of Genetic Risk and Longitudinal Transmission Processes Underlying Maternal Parenting and Psychopathology and Children's ADHD Symptoms and Aggression: Utilizing the Advantages of a Prospective Adoption Design.

Behav Genet 2020 Jul 4. Epub 2020 Jul 4.

Prevention Science Institute, University of Oregon, Eugene, OR, USA.

Although genetic factors may contribute to initial liability for ADHD onset, there is growing evidence of the potential importance of the rearing environment on the developmental course of ADHD symptomatology. However, associations between family-level variables (maternal hostility, maternal depressive symptoms) and child behaviors (developmental course of ADHD and aggression) may be explained by genes that are shared by biologically related parents and children. Furthermore, ADHD symptoms and aggression commonly co-occur: it is important to consider both simultaneously to have a better understanding of processes underlying the developmental course of ADHD and aggression. Read More

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http://dx.doi.org/10.1007/s10519-020-10006-yDOI Listing

Parent- and Child-Factors in Specific Phobias: The Interplay of Overprotection and Negative Affectivity.

J Abnorm Child Psychol 2020 Jul 4. Epub 2020 Jul 4.

Child Study Center, Virginia Tech, Blacksburg, VA, USA.

Specific phobias are among the most prevalent anxiety disorders in children and adolescents. Although brief and intensive treatments are evidence-based interventions (Davis III et al. Annual Review of Clinical Psychology, 15, 233-256, 2019), up to one-third of youth do not show significant change in their symptoms following these interventions. Read More

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http://dx.doi.org/10.1007/s10802-020-00662-3DOI Listing

Handedness and Birth Order Among Heterosexual Men, Gay Men, and Sao Praphet Song in Northern Thailand.

Arch Sex Behav 2020 Jul 5. Epub 2020 Jul 5.

Department of Psychology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.

Previous research has examined handedness and birth order to inform sexual orientation and gender identity/role expression development; however, sexual orientation and gender identity/role expression have rarely been disentangled to provide a more nuanced perspective. In Thailand, we investigated sexual orientation and gender identity simultaneously via comparison of 282 heterosexual men, 201 gay men, and 178 sao praphet song-i.e. Read More

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http://dx.doi.org/10.1007/s10508-020-01774-zDOI Listing

Randomised Controlled Trial of a Therapeutic Playgroup for Children with Developmental Delays.

J Autism Dev Disord 2020 Jul 4. Epub 2020 Jul 4.

School of Occupational Therapy, Social Work and Speech Pathology, Curtin University, Perth, WA, Australia.

A single-blind randomised control trial investigated the effectiveness of the Learn, Engage and Play (LEaP) playgroup. Seventy-one children with developmental delay were randomly allocated to an 8-week LEaP playgroup or control group and followed up at 12 and 28 weeks. On the primary outcome measure, LEaP demonstrated significant within group changes at 28 weeks (parenting distress p = 0. Read More

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http://dx.doi.org/10.1007/s10803-020-04580-7DOI Listing

Inverse in silico-in vitro fishing of unexpected paroxetine kinase targets from tumor druggable kinome.

J Mol Model 2020 Jul 4;26(8):197. Epub 2020 Jul 4.

Department of Gynaecology, Huai'an Maternal and Child Health Care Center, The Affiliated Hospital of Yangzhou University Medical College, Huai'an, 223000, China.

The serotonin selective reuptake inhibitor paroxetine has been clinically observed to reposition a significant suppressing potency on human tumors by unexpectedly targeting diverse kinase pathways involved in tumorigenesis. Here, we describe an inverse in silico-in vitro strategy to fish potential kinase targets using the paroxetine as bait. This is different (inverse) to the traditional drug discovery process that commonly screens small-molecule inhibitors for a specific kinase target. Read More

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http://dx.doi.org/10.1007/s00894-020-04444-yDOI Listing

Ante-natal counseling in phacomatoses.

Childs Nerv Syst 2020 Jul 5. Epub 2020 Jul 5.

Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Objectives: Phacomatoses are a group of neuro-oculo-cutaneous syndromes/ neurocutaneous disorders, involving structures arising from the embryonic ectoderm. Most of phacomatoses including the most common ones:, neurofibromatosis type I and type II (NF1, NF2) and tuberosclerosis complex (TSC), are autosomal dominant genetic disorders with full penetrance and variable expression. As no effective treatment exists, the only way to prevent the disease, is by prenatal genetic diagnosis (either chorionic villus sampling-CVS or amniocentesis-AC) and termination of pregnancy or performing preimplantation genetic testing (PGT). Read More

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http://dx.doi.org/10.1007/s00381-020-04776-3DOI Listing

Genetic risks of schizophrenia identified in a matched case-control study.

Eur Arch Psychiatry Clin Neurosci 2020 Jul 4. Epub 2020 Jul 4.

Department of Psychiatry, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuou-ku, Chiba, Chiba, 260-8670, Japan.

It has been suggested that dopaminergic neurotransmission plays important roles for the psychotic symptoms and probably etiology of schizophrenia. In our recent preliminary study, we demonstrated that the specific allele combinations of dopamine-related functional single nucleotide polymorphisms (SNPs), rs10770141, rs4680, and rs1800497 could indicate risks for schizophrenia. The present validation study involved a total of 2542 individuals who were age- and sex-matched in a propensity score matching analysis, and the results supported the statistical significances of the proposed genetic risks described in our previous reports. Read More

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http://dx.doi.org/10.1007/s00406-020-01158-3DOI Listing

Population pharmacokinetics-pharmacodynamics of sunitinib in pediatric patients with solid tumors.

Cancer Chemother Pharmacol 2020 Jul 4. Epub 2020 Jul 4.

Pfizer Global Product Development, 10646 Science Center Drive, CB10, La Jolla, CA, 92121, USA.

Purpose: The safety profile of sunitinib in children, including the impact of sunitinib exposure on safety endpoints, was assessed using population pharmacokinetic (PK) and pharmacokinetic-pharmacodynamic (PK-PD) models.

Methods: Data were from two clinical studies in 59 children with solid tumors (age range 2-21 years, 28 male/31 female, body weight range 16.2-100 kg, body surface are [BSA] range 0. Read More

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http://dx.doi.org/10.1007/s00280-020-04106-zDOI Listing

Association of sleep characteristics with adiposity markers in children.

J Pediatr Endocrinol Metab 2020 Jul 4. Epub 2020 Jul 4.

IFB Adiposity Diseases, Leipzig University, Leipzig, Germany.

Background Accumulating evidence suggests a relationship between sleep alterations and overweight/obesity in children. Our aim was to investigate the association of sleep measures other than obstructive sleep apnea or sleep duration with overweight/obesity and metabolic function in children. Methods We conducted a prospective cohort study in school- aged children (aged 5 to 8 years, prepubertal, and 12 to 15 years, pubertal) with overweight/obesity and normal-weight children. Read More

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http://dx.doi.org/10.1515/jpem-2019-0517DOI Listing

Drainage, irrigation and fibrinolytic therapy (DRIFT) for posthaemorrhagic ventricular dilatation: 10-year follow-up of a randomised controlled trial.

Arch Dis Child Fetal Neonatal Ed 2020 Jul 4. Epub 2020 Jul 4.

Neonatal Neurology, Bristol Medical School, Faculty of Health Sciences, University of Bristol, Bristol, UK.

Background: Progressive ventricular dilatation after intraventricular haemorrhage (IVH) in preterm infants has a very high risk of severe disability and death. Drainage, irrigation and fibrinolytic therapy (DRIFT), in a randomised controlled trial (RCT), reduced severe cognitive impairment at 2 years.

Objective: To assess if the cognitive advantage of DRIFT seen at 2 years persisted until school age. Read More

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http://dx.doi.org/10.1136/archdischild-2019-318231DOI Listing

Characteristics of peer play in children with visual impairments.

Res Dev Disabil 2020 Jul 2;105:103714. Epub 2020 Jul 2.

Behavioural Science Institute, Radboud University, Montessorilaan 3, 6525 HR, Nijmegen, the Netherlands. Electronic address:

Background: Although many studies report children with vision impairments (VIs) experience play difficulties compared to sighted peers, large variation is present within the population of children with VIs.

Aims: The present study investigated peer play variation in 70 elementary school-aged children with VIs (M age = 8;11 years, SD = 2.25) and associations with specific child characteristics in sub-groups of participants. Read More

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http://dx.doi.org/10.1016/j.ridd.2020.103714DOI Listing

Social cohesion, depression, and substance use severity among young men: Cross-sectional and longitudinal analyses from a Swiss cohort.

Addict Behav 2020 Jun 15;110:106510. Epub 2020 Jun 15.

Department of Child and Adolescent Psychiatry and Psychotherapy, University Hospital of Psychiatry Zurich, University of Zurich, Zurich, Switzerland; La Source, School of Nursing Sciences, HES-SO University of Applied Sciences and Arts of Western Switzerland, Lausanne, Switzerland. Electronic address:

Introduction: Social cohesion, depression, and problematic substance use are intertwined and poorly understood.This study aimed to examine cross-sectional and longitudinal associations between social cohesion, depression and problematic substance use amongyoung men, age 21-25.

Methods: We used 2nd wave (t, 2012-2014, N = 6020) and 3rd wave (t, 2016-2018) data from the on-going Swiss CohortStudy on Substance Use Risk Factors (C-SURF), assessing social cohesion, depression, and severity of alcohol, nicotine and cannabis use during both waves. Read More

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http://dx.doi.org/10.1016/j.addbeh.2020.106510DOI Listing

'That is why we raise children': African American fathers' race-related concerns for their adolescents and parenting strategies.

J Adolesc 2020 Jul 2;82:67-81. Epub 2020 Jul 2.

University of North Carolina at Chapel Hill, United States.

Introduction: The current study highlights the voices and perspectives of African American fathers, with specific emphasis on their race-related concerns for their adolescents as well as how these concerns guide their parenting strategies.

Method: Twenty-four African American fathers participated in 1.5-3 h long focus group interviews. Read More

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http://dx.doi.org/10.1016/j.adolescence.2020.06.001DOI Listing

Human exposure to particles at the air-water interface: Influence of water quality on indoor air quality from use of ultrasonic humidifiers.

Environ Int 2020 Jul 2;143:105902. Epub 2020 Jul 2.

Department of Civil & Environmental Engineering, Virginia Tech, Blacksburg, VA, USA. Electronic address:

Ultrasonic humidifiers provide indoor relief to symptoms caused by dry air and produce aerosols containing both water and minerals that are present in the water that fills the humidifier. This study investigated the spatial distributions, concentrations, and metal and mineral composition of aerosols emitted when an ultrasonic humidifier was filled with deionized water (DI), low mineral tap water (LL), high total dissolved solids (TDS)/high hardness water (HH), and high TDS/low hardness water (HL). Aerosol/particle sizes and counts were obtained at six horizontal distances in both the plume and near floor for each water quality. Read More

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http://dx.doi.org/10.1016/j.envint.2020.105902DOI Listing

Electrophysiological dynamics of false belief understanding and complementation syntax in school-aged children: Oscillatory brain activity and event-related potentials.

J Exp Child Psychol 2020 Jul 2;198:104905. Epub 2020 Jul 2.

Department of Psychology, University of Florida, Gainesville, FL 32611, USA.

A large body of research in developmental psychology has been devoted to the ongoing debate over which aspects of language are fundamental to false belief understanding (FBU). A key proposal from de Villiers and colleagues proposes the essential role of complementation syntax in FBU development. The current study, using scalp electroencephalography (EEG), addressed one opposing hypothesis purporting that complementation is redundant to FBU by characterizing the electrophysiological correlates of FBU and complementation syntax in school-age children. Read More

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http://dx.doi.org/10.1016/j.jecp.2020.104905DOI Listing

Young children and adults associate social power with indifference to others' needs.

J Exp Child Psychol 2020 Jul 2;198:104867. Epub 2020 Jul 2.

Department of Psychology, University of Maryland, College Park, MD 20742, USA.

In hierarchical societies, what do we expect from people at the top? Early in life, children use horizontal relationships (e.g., affiliation) to predict selectivity in others' prosocial behavior. Read More

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http://dx.doi.org/10.1016/j.jecp.2020.104867DOI Listing

The crosslinguistic acquisition of sentence structure: Computational modeling and grammaticality judgments from adult and child speakers of English, Japanese, Hindi, Hebrew and K'iche'.

Cognition 2020 Jun 26;202:104310. Epub 2020 Jun 26.

Universidad del Valle de Guatemala, Guatemala.

This preregistered study tested three theoretical proposals for how children form productive yet restricted linguistic generalizations, avoiding errors such as *The clown laughed the man, across three age groups (5-6 years, 9-10 years, adults) and five languages (English, Japanese, Hindi, Hebrew and K'iche'). Participants rated, on a five-point scale, correct and ungrammatical sentences describing events of causation (e.g. Read More

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http://dx.doi.org/10.1016/j.cognition.2020.104310DOI Listing

The prenatal, postnatal, neonatal, and family environmental risk factors for Developmental Coordination Disorder: A study with a national representative sample.

Res Dev Disabil 2020 Jul 2;104:103699. Epub 2020 Jul 2.

Department of Psychology, Health and Professional Development, Oxford Brookes University, UK.

Knowledge of obstetric and environmental influences on Developmental Coordination Disorder (DCD) helps provide increased understanding of the mechanisms underlying the disorder. However, the literature to date has not adequately examined the obstetric and environmental risk factors for DCD in a population-based sample. The current study was therefore conducted to explore the prenatal, perinatal, neonatal, and family environmental risk factors for DCD. Read More

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http://dx.doi.org/10.1016/j.ridd.2020.103699DOI Listing

Awareness of sudden unexpected death in epilepsy among parents of children with epilepsy in a tertiary center.

Epilepsy Behav 2020 Jul 2;111:107125. Epub 2020 Jul 2.

Marmara University, School of Medicine, Department of Public Health and Epilepsy Research and Implementation Centre, Istanbul, Turkey.

Objective: Sudden unexpected death in epilepsy (SUDEP) is the second leading neurological cause of potential years of lifelost after stroke. Despite growing numbers of studies on social aspects of epilepsy, there is a paucity of research on the awareness of SUDEP among the parents of children with epilepsy (CWE), especially in Turkey. In this study, we aimed to evaluate the knowledge of parents of the CWE regarding SUDEP in the tertiary setting. Read More

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http://dx.doi.org/10.1016/j.yebeh.2020.107125DOI Listing

Predictors of behavioral dysregulation and social dysfunction in pediatric patients with epilepsy and obesity: Developmental timing matters.

Epilepsy Behav 2020 Jul 1;111:107234. Epub 2020 Jul 1.

Neuropsychology Section in Department of Psychiatry; University of Michigan, Ann Arbor, 2101 Commonwealth Blvd. Suite C, Ann Arbor, MI 55455, United States of America.

Childhood obesity has been associated with greater risks of psychopathology, including externalizing behaviors and social dysfunction. However, there has been limited research on the effect of obesity on psychosocial functioning among pediatric patients with epilepsy. Accordingly, this study aimed to examine the association between overweight/obesity and behavioral and social functioning among pediatric patients with epilepsy, as function of their developmental status. Read More

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http://dx.doi.org/10.1016/j.yebeh.2020.107234DOI Listing

The effect of movie-watching on electroencephalographic responses to tactile stimulation.

Neuroimage 2020 Jul 2:117130. Epub 2020 Jul 2.

Department of Radiology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada; Child and Adolescent Imaging Research (CAIR) Program, University of Calgary, Calgary, Alberta, Canada; Alberta Children's Hospital Research Institute, University of Calgary, Calgary, Alberta, Canada; Hotchkiss Brain Institute, University of Calgary, Calgary, Alberta, Canada.

Movie-watching is becoming a popular acquisition method to increase compliance and enable neuroimaging data collection in challenging populations such as children, with potential to facilitate studying the somatosensory system. However, relatively little is known about the possible crossmodal (audiovisual) influence of movies on cortical somatosensory processing. In this study, we examined the impact of dynamic audiovisual movies on concurrent cortical somatosensory processing using electroencephalography (EEG). Read More

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http://dx.doi.org/10.1016/j.neuroimage.2020.117130DOI Listing

Role of Color Doppler Imaging in Diagnosis of Carotid Atherosclerosis and Nerve Damage in Patients with Bacterial Infection.

Neurosci Lett 2020 Jul 2:135228. Epub 2020 Jul 2.

Department of Ultrasound, Shenzhen University General Hospital, Shenzhen, 518055, Guangdong Province, China. Electronic address:

To investigate the diagnostic value of carotid color doppler imaging information technology on carotid atherosclerosis and nerve damage and analyze the influence of helicobacter pylori (HP) infection on the expression level of inflammation cytokines related to carotid atherosclerosis stability, 118 cases of carotid atherosclerosis patients were divided into HP infection group (60 cases) and uninfected group (58 cases) by 14C-UBT test. The carotid artery intima-media thickness (CIMT) (including the bifurcation of carotid artery (CB), the common carotid artery (CCA), and the intimal carotid arties (CCI)) and the differences in plaque morphology were analyzed using the computer information technology of ultrasound imaging. The expression levels of myeloperoxidase (MPO), matrix metalloproteinase-9 (MMP-9), and lipoprotein associated phospholipase A2 (LP-PLA2) were detected by enzyme-linked immunosorbent assay. Read More

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http://dx.doi.org/10.1016/j.neulet.2020.135228DOI Listing

Risk of recurrent herpes zoster in a population-based cohort study of older adults.

J Am Acad Dermatol 2020 Jul 2. Epub 2020 Jul 2.

School of Public Health and Community Medicine, University of New South Wales, Sydney, NSW, Australia.

Background: There is limited data on zoster recurrence.

Objective: To examine in detail zoster recurrence in a population-based cohort.

Methods: Using data from a large cohort (The 45 and Up Study) with linked medical data (2004-2015), the incidence of first and recurrent zoster was examined using survival analyses methods. Read More

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http://dx.doi.org/10.1016/j.jaad.2020.06.1013DOI Listing

Role of selected criteria and preventive chemotherapy in tumor recurrence after liver transplantation.

Hepatobiliary Pancreat Dis Int 2020 Jun 21. Epub 2020 Jun 21.

Institute of Organ Transplantation, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Ministry of Education, Wuhan 430030, China; NHC Key Laboratory of Organ Transplantation, Wuhan 430030, China; Key Laboratory of Organ Transplantation, Chinese Academy of Medical Sciences, Wuhan 430030, China.

Background: Long-term survival after liver transplantation (LT) for hepatocellular carcinoma (HCC) patients remains poor because of tumor recurrence. To improve the prognosis of HCC patients after LT, we aimed to identify different transplantation criteria and risk factors related to tumor recurrence and evaluate the effect of preventive chemotherapy in a single center.

Methods: In total, data on 20 variables and the survival of 199 patients with primary HCC who underwent LT between 2005 and 2015 were included for analysis. Read More

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http://dx.doi.org/10.1016/j.hbpd.2020.06.008DOI Listing

BAL inflammatory markers can predict pulmonary exacerbations in children with cystic fibrosis.

Chest 2020 Jul 2. Epub 2020 Jul 2.

Department of Respiratory and Sleep Medicine, Perth Children's Hospital, Perth, Australia; Telethon Kids Institute, Perth, Australia.

Background: Pulmonary exacerbations in cystic fibrosis are characterized by airway inflammation and may cause irreversible lung damage. Early identification of such exacerbations may facilitate early initiation of treatment, thereby potentially reducing long-term morbidity.

Research Question: Is it possible to predict pulmonary exacerbations in children with cystic fibrosis using inflammatory markers obtained from bronchoalveolar lavage (BAL) fluid?

Study Design: and Methods: A longitudinal analysis of children aged 0-7 years included in the Australian Respiratory Early Surveillance Team for Cystic Fibrosis (AREST CF) study between 2005 and 2015. Read More

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http://dx.doi.org/10.1016/j.chest.2020.06.044DOI Listing

Applying cognitive behavioral therapy and thought field therapy in Kurdistan region of Iraq: A retrospective case series study of mental-health interventions in a setting of political instability and armed conflicts.

Explore (NY) 2020 Jun 25. Epub 2020 Jun 25.

Research Institute, Modum Bad Psychiatric Center, Vikersund, Norway; Department of Psychology, University of Oslo, Oslo, Norway. Electronic address:

Background: Mass violence, atrocities, and political upheavals have affected the prosperity and psychological health of the people of Iraq. Those living in the Garmian region of the Kurdistan Region of Iraq are among those most affected. While there is an urgent need for mental health interventions in this region, mental health resources are scarce, and only a small percentage of the population in need receive mental health care. Read More

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http://dx.doi.org/10.1016/j.explore.2020.06.003DOI Listing

Moxibustion with deferasirox results in safe, accelerated, and sustained cardiac iron chelation for a young Diamond Blackfan Anemia patient: An integrative case report.

Explore (NY) 2020 May 23. Epub 2020 May 23.

Chiyu Center, 201 Coffman St., PO Box 605, Longmont, Colorado 80501, United States; Kansas City VA Medical Center, 4801 Linwood Blvd., Kansas City, MO 64128, United States; 933 McGee St., Unit 326, Kansas City, MO 64106, United States. Electronic address:

Diamond Blackfan Anemia (DBA) is a rare blood disorder of bone marrow failure typically identified in the first year of life. Due to treatment limitations, nearly all DBA patients are reliant upon chronic red cell infusion for some period of their lives. Repeat blood transfusion invariably leads to iron overload, which creates significant and life-threatening side effects. Read More

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http://dx.doi.org/10.1016/j.explore.2020.05.011DOI Listing

Reducing courtship time promotes marital bliss: The Battle of the Sexes game revisited with costs measured as time lost.

J Theor Biol 2020 Jul 2:110382. Epub 2020 Jul 2.

Department of Mathematics, Faculty of Science, University of South Bohemia, Branišovská 1760, 370 05 České Budějovice, Czech Republic; Czech Academy of Sciences, Biology Centre, Institute of Entomology, Branišovská 31, 370 05 České Budějovice, Czech Republic. Electronic address:

Classic bimatrix games, that are based on pair-wise interactions between two opponents belonging to different populations, do not consider the cost of time. In this article, we build on an old idea that lost opportunity costs affect individual fitness. We calculate fitnesses of each strategy for a two-strategy bimatrix game at the equilibrium distribution of the pair formation process that includes activity times. Read More

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http://dx.doi.org/10.1016/j.jtbi.2020.110382DOI Listing

Prevalence and clinical characteristics of children with medical complexity in Tottori Prefecture, Japan: A population-based longitudinal study.

Brain Dev 2020 Jul 1. Epub 2020 Jul 1.

Division of Child Neurology, Department of Brain and Neurosciences, Faculty of Medicine, Tottori University, Yonago, Japan.

Objectives: To investigate the prevalence and background of children with medical complexity (CMC) and its secular trend in Japan.

Methods: CMC were defined as patients under the age of 20 years requiring medical care and devices. The patients were enrolled using the national health insurance claims data of three hospitals and two rehabilitation centers in Tottori Prefecture. Read More

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http://dx.doi.org/10.1016/j.braindev.2020.06.008DOI Listing

Fertility in multiple sclerosis patients: still many unanswered questions.

Reprod Biomed Online 2020 Jun 14. Epub 2020 Jun 14.

Physiopathology of Human Reproduction Unit, IRCCS Ospedale Policlinico San Martino, Genova, Italy.

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http://dx.doi.org/10.1016/j.rbmo.2020.06.003DOI Listing

Compromised IGF signaling causes caspase-6 activation in Huntington disease.

Exp Neurol 2020 Jul 2:113396. Epub 2020 Jul 2.

Department of Medical Genetics, Centre for Molecular Medicine and Therapeutics, Child and Family Research Institute, University of British Columbia, 950 West 28th Avenue, Vancouver, BC V5Z 4H4, Canada. Electronic address:

Huntington disease (HD) is an autosomal dominant neurodegenerative disorder caused by an expansion of a polyglutamine repeat in the huntingtin (HTT) protein. Aberrant activation of caspase-6 and cleavage of mutant HTT generating the toxic N-terminal 586 HTT fragment are important steps in the pathogenesis of HD. Similarly, alterations in the insulin-like growth factor 1 (IGF-1) signaling pathway have been implicated in the disease as a result of decreased plasma IGF-1 levels in HD patients. Read More

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http://dx.doi.org/10.1016/j.expneurol.2020.113396DOI Listing

Thirty years of the CRC: Child protection progress, challenges and opportunities.

Child Abuse Negl 2020 Jul 1:104436. Epub 2020 Jul 1.

Sydney Law School, University of Sydney, Australia. Electronic address:

The CRC has a challenging and ambitious agenda in relation to the protection of children from all forms of violence, particularly the large and increasing numbers of children affected by natural disasters, armed conflict, trafficking, poverty and increasing inequality, displacement and trafficking. In this article, we outline some of the issues in the implementation and understanding of the Convention and highlight three major international developments over the last decade: the adoption of General Comment No 13, the work of the Special Representative of the Secretary General on Violence Against Children, and the adoption of the 2030 Agenda for Sustainable Development by the UN General Assembly in 2005. We also identify four broad domains in which the Convention can and is being used to enhance efforts to ensure the protection of children based on a rights framework - advocacy and litigation, policy design, service delivery and research and monitoring methodology - rather than a welfare-based approach. Read More

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http://dx.doi.org/10.1016/j.chiabu.2020.104436DOI Listing

Patterns of Osteopontin Expression in Abusive Head Trauma Compared With Other Causes of Pediatric Traumatic Brain Injury.

J Pediatr 2020 Jul 2. Epub 2020 Jul 2.

Children's Healthcare of Atlanta, Atlanta GA.

Objective: To examine levels of plasma osteopontin (OPN), a recently described neuroinflammatory biomarker, in children with abusive head trauma compared with other types of traumatic brain injury.

Study Design: Patients included children <4 years diagnosed with TBI and seen in the ICU in a tertiary children's hospital. Patients were classified as having confirmed or suspected abusive head trauma, or TBI by other mechanisms (eg, motor vehicle accidents), as identified by a Child Protection Team clinician. Read More

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http://dx.doi.org/10.1016/j.jpeds.2020.06.080DOI Listing

The Hikikomori Phenomenon of Social Withdrawal: An Emerging Condition Involving Youth's Mental Health and Social Participation.

J Pediatr 2020 Jul 2. Epub 2020 Jul 2.

European Paediatric Association/Union of National European Paediatric Societies and Associations (EPA/UNEPSA), Berlin, Germany;; 2nd Pediatric Clinic, Mother and Child Department, University of Medicine and Pharmacy Iuliu Haţieganu Cluj-Napoca, Emergency Clinical Hospital for Children Cluj-Napoca, Romania.

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http://dx.doi.org/10.1016/j.jpeds.2020.06.089DOI Listing

Use of phospholipase C zeta analysis to identify candidates for artificial oocyte activation: a case series of clinical pregnancies and a proposed algorithm for patient management.

Fertil Steril 2020 Jul;114(1):163-174

Nuffield Department of Women's and Reproductive Health, University of Oxford, Oxford, United Kingdom. Electronic address:

Objective: To investigate the applicability of phospholipase C zeta (PLCζ) analysis in assisting the clinical decision-making process when considering artificial oocyte activation (AOA) for infertile males in assisted reproductive technology.

Design: Fifty-six males (43 infertile/13 fertile) were screened using our PLCζ assay.

Setting: Fertility unit/university laboratory. Read More

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http://dx.doi.org/10.1016/j.fertnstert.2020.02.113DOI Listing

Fertility issues and pregnancy outcomes in Turner syndrome.

Fertil Steril 2020 Jul;114(1):144-154

Oxford Centre for Diabetes, Endocrinology and Metabolism, Oxford University Hospitals NHS Trust, Oxford, United Kingdom.

Objective: To study fertility issues and pregnancy outcomes in Turner syndrome (TS).

Design: Retrospective cohort study.

Setting: Not applicable. Read More

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http://dx.doi.org/10.1016/j.fertnstert.2020.03.002DOI Listing
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