6,394 results match your criteria Child's Nervous System[Journal]


Drug-resistant epilepsy in Indian children at a tertiary-care public hospital.

Childs Nerv Syst 2019 Feb 13. Epub 2019 Feb 13.

Department of Pediatrics, Lok Nayak Hospital, Maulana Azad Medical College, University of Delhi, 2, BSZ Marg, New Delhi, Delhi, 110002, India.

Background: Drug-resistant epilepsy (DRE), a condition in which seizures persist and seizure freedom is unlikely to be attained with further manipulation of anti-epileptic drugs, occurs in around 20% of children with epilepsy. This study was conducted with the aim to study the profile of Indian children with resistant epilepsy, using the new consensus definition of DRE.

Methods: All children who had been attending the Pediatric Neurology Clinic regularly for at least 6 months were reviewed between April and September 2015. Read More

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http://dx.doi.org/10.1007/s00381-019-04084-5DOI Listing
February 2019
1 Read

Pfeiffer type 2 syndrome: review with updates on its genetics and molecular biology.

Childs Nerv Syst 2019 Feb 11. Epub 2019 Feb 11.

Seattle Science Foundation, 550 17th Ave, James Tower, Suite 600, Seattle, WA, 98122, USA.

Introduction: Pfeiffer syndrome is a rare autosomal dominant inherited disorder associated with craniosynostosis, midfacial hypoplasia, and broad thumbs and toes. The syndrome has been divided into three clinical subtypes based on clinical findings.

Methods: This review will specifically examine the most severe type, Pfeiffer syndrome type 2, focusing on its genetics and molecular biology. Read More

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http://dx.doi.org/10.1007/s00381-019-04082-7DOI Listing
February 2019

Port-a-cath and ventriculoatrial shunt at the same atrium: technical note.

Childs Nerv Syst 2019 Feb 6. Epub 2019 Feb 6.

Department of Neurosurgery, University of Health Sciences, Gulhane Training and Research Hospital, 06010 Etlik, Ankara, Turkey.

Hydrocephalus is a rare complication of brain involving acute lymphoblastic leukemia (ALL). The standard treatment is ventriculoperitoneal (VP) shunting, while ventriculoatrial (VA) shunting is the second option in a case of VP shunt failure in young children. But the presence of port catheter at the right atrium restricts and makes a VA shunt difficult to place in the same atrium. Read More

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http://dx.doi.org/10.1007/s00381-019-04079-2DOI Listing
February 2019
1 Read

TROPHY registry study design: a prospective, international multicenter study for the surgical treatment of posthemorrhagic hydrocephalus in neonates.

Childs Nerv Syst 2019 Feb 6. Epub 2019 Feb 6.

Pediatric Neurosurgery, Universitätsmedizin Göttingen, Göttingen, Germany.

Introduction: Among children with hydrocephalus, neonates with intraventricular hemorrhage (IVH) and posthemorrhagic hydrocephalus (PH) are considered a group with one of the highest complication rates of treatment. Despite continued progress in neonatal care, a standardized and reliable guideline for surgical management is missing for this challenging condition. Thus, further research is warranted to compare common methods of surgical treatment. Read More

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http://dx.doi.org/10.1007/s00381-019-04077-4DOI Listing
February 2019
1 Read

An unusual presentation of bobble-head doll syndrome in a patient with hydranencephaly and Chiari 3 malformation.

Childs Nerv Syst 2019 Feb 6. Epub 2019 Feb 6.

Department of Surgery, Division of Neurosurgery, College of Health Sciences, University of Zimbabwe, P.O Box A178, Avondale, Harare, Zimbabwe.

Bobble-head doll syndrome is a rare movement disorder that is usually associated with lesions involving the third ventricle. It is characterised by stereotypical rhythmic up-and-down or side-to-side head movements. The pathophysiology and anatomical basis for this unusual manifestation is still a subject of intense scrutiny. Read More

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http://dx.doi.org/10.1007/s00381-019-04054-xDOI Listing
February 2019

Establishing reproducible predictors of cerebellar mutism syndrome based on pre-operative imaging.

Childs Nerv Syst 2019 Feb 6. Epub 2019 Feb 6.

Department of Pediatric Neurosurgery, Beijing Tiantan Hospital, Capital Medical University, Beijing, China.

Purpose: To establish some explicit, feasible, and reproducible predictors for CMS.

Materials And Methods: This study was a retrospective case study. Data were obtained from 82 patients with medulloblastoma at a single center, Beijing Tiantan Hospital. Read More

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http://dx.doi.org/10.1007/s00381-019-04075-6DOI Listing
February 2019
1 Read

Human tail-like cutaneous appendage with a contiguous stalk of limited dorsal myeloschisis.

Childs Nerv Syst 2019 Feb 6. Epub 2019 Feb 6.

Department of Neurosurgery, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.

Purpose: Limited dorsal myeloschisis (LDM) is characterized by a fibroneural stalk linking the skin lesion to the underlying spinal cord. On account of the external skin lesion, all LDMs are either flat (nonsaccular) or saccular, and a human tail-like cutaneous appendage has not been reported.

Methods: In our 14 LDM patients, 2 had tail-like appendages. Read More

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http://dx.doi.org/10.1007/s00381-019-04071-wDOI Listing
February 2019

Hypertrophic pachymeningitis: idiopathic or secondary?

Childs Nerv Syst 2019 Feb 5. Epub 2019 Feb 5.

Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

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http://dx.doi.org/10.1007/s00381-019-04080-9DOI Listing
February 2019
1.163 Impact Factor

Intracranial arterial dolichoectasia and skull damage in a girl with Jaffe-Campanacci syndrome: a case report.

Childs Nerv Syst 2019 Feb 5. Epub 2019 Feb 5.

Department of Neurosurgery, Children's Hospital of Soochow University, 92 Zhongnan Street, Suzhou, Jiangsu, 215006, People's Republic of China.

ᅟJaffe-Campanacci is a rare syndrome characterised by axillary freckles, multiple non-ossifying fibromas of the long bones and jaw, and café-au-lait spots, associated with some features of neurofibromatosis type 1 (NF1). Cherix et al. and Colby and Saul suggested that Jaffe-Campanacci syndrome (JCS) might be a distinct form of NF1. Read More

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http://dx.doi.org/10.1007/s00381-019-04064-9DOI Listing
February 2019

Old drugs still work! Oral etoposide in a relapsed medulloblastoma.

Childs Nerv Syst 2019 Feb 1. Epub 2019 Feb 1.

Department of Pediatric Oncology, Hospital Universitario Niño Jesús, Avenida Menendez Pelayo, 65, 28009, Madrid, Spain.

Medulloblastoma is the most common malignant brain tumor in children. Approximately 30% of children with medulloblastoma will progress or relapse despite being treated. New therapies have been proposed in recent years, including high-dose chemotherapy, immunotherapy, and targeted therapy. Read More

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http://dx.doi.org/10.1007/s00381-019-04072-9DOI Listing
February 2019
1 Read

Pediatric nodular fasciitis at the roof of the optic canal causing decreased vision: case report and review of the literature.

Childs Nerv Syst 2019 Feb 1. Epub 2019 Feb 1.

Division of Neurosurgery, National Center for Child Health and Development, Okura 2-10-1, Setagaya-ku, Tokyo, 157-8535, Japan.

We present a 3-year-old girl with decreased visual acuity of the left eye. Radiological studies revealed a mass lesion at the roof of the left optic canal with bony erosion, which compressed the left optic nerve. Gross total resection of the mass and decompression of the optic canal were performed. Read More

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http://dx.doi.org/10.1007/s00381-019-04057-8DOI Listing
February 2019

Diffuse intrinsic pontine glioma ventricular peritoneal shunt metastasis: a case report and literature review.

Childs Nerv Syst 2019 Jan 31. Epub 2019 Jan 31.

Pediatric Neuro-Oncology, The Hospital for Sick Children, University of Toronto, Toronto, ON, M5H 1X8, Canada.

Dissemination of diffuse intrinsic pontine glioma (DIPG) outside the central nervous system is exceptional. Here, we present a child diagnosed with DIPG who developed seeding along the track of the ventriculoperitoneal shunt and review the literature on this unusual occurrence. Read More

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http://dx.doi.org/10.1007/s00381-019-04069-4DOI Listing
January 2019

EEG lateralization and seizure outcome following peri-insular hemispherotomy for pediatric hemispheric epilepsy.

Childs Nerv Syst 2019 Jan 30. Epub 2019 Jan 30.

Department of Neurological Sciences, Christian Medical College, Vellore, Tamil Nadu, India.

Objective: To determine whether preoperative non-lateralizing scalp electroencephalography (EEG) influences seizure outcome following peri-insular hemispherotomy (PIH) in pediatric hemispheric epilepsy.

Methods: Retrospective data was collected on all 45 pediatric patients who underwent PIH between 2005 and 2016. All underwent a basic pre-surgical evaluation consisting of detailed history and examination, neuropsychological assessment, MRI, and EEG. Read More

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http://link.springer.com/10.1007/s00381-019-04067-6
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http://dx.doi.org/10.1007/s00381-019-04067-6DOI Listing
January 2019
6 Reads

Microvascular decompression with partial occipital condylectomy in a case of pediatric spasmodic torticollis.

Childs Nerv Syst 2019 Jan 30. Epub 2019 Jan 30.

National Brain Aneurysm & Tumor Center, United Hospital, 3033 Excelsior Boulevard, Suite 495, Minneapolis, MN, 55416, USA.

Spasmodic torticollis is a rare, neurologic disorder that is caused by abnormal nerve compression of the 11th cranial nerve by blood vessels or bony protrusions. It is typically treated pharmacologically and, if necessary, with surgical intervention. We report a unique case of spasmodic torticollis in a 15-year-old female that involved abnormal compression of the left 11th cranial nerve (CN) by the left vertebral artery, displaced by a hypertrophic left occipital condyle. Read More

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http://dx.doi.org/10.1007/s00381-019-04065-8DOI Listing
January 2019

Correction to: Congenital pial AVF along the falx cerebri with complete agenesis of the corpus callosum and bilateral parasagittal pachygyria-polymicrogyria secondary to chronic ischemia.

Childs Nerv Syst 2019 Jan 29. Epub 2019 Jan 29.

Department of Diagnostic Imaging, National University Health System, 1E Kent Ridge Rd, Singapore, 119228, Singapore.

The article which was recently published contained error. Fig. 1 was incorrectly processed as Fig. Read More

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http://dx.doi.org/10.1007/s00381-019-04052-zDOI Listing
January 2019

Subdural haematoma in neonates following forceps-assisted delivery: case series and review of the literature.

Childs Nerv Syst 2019 Jan 28. Epub 2019 Jan 28.

Department of Paediatric Neurosurgery, University Hospital of Wales, Cardiff, UK.

Purpose: Subdural haematoma (SDH) is a recognised complication of forceps-assisted delivery (FAD). There are no guidelines regarding its management. This study aims to provide a better insight into the management and outcomes of neonatal SDH post-FAD. Read More

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http://dx.doi.org/10.1007/s00381-018-04043-6DOI Listing
January 2019
1 Read

Tumor necrosis factor alpha and interleukin-1 beta levels in cerebrospinal fluid examination for the diagnosis of ventriculoperitoneal shunt-related ventriculitis.

Childs Nerv Syst 2019 Jan 28. Epub 2019 Jan 28.

Department of Neurosurgery, Adana City Training Research Hospital, Adana, Turkey.

Purpose: Ventriculitis is known to develop after chronic inflammation and bacterial invasion of the ventricular surface with a recurrence of shunt infections. The aim of this study is to evaluate the diagnostic value of elevation in cerebrospinal fluid (CSF) interleukin-1 beta (IL-1β) and tumor necrosis factor alpha (TNF-α) together with CSF culture and laboratory test results in the diagnosis of ventriculoperitoneal (VP) shunt-related ventriculitis, which is known to be more problematic than conventional shunt infection.

Methods: The study included a total of 34 patients with a VP shunt due to hydrocephalus, who presented with a headache, fever, and shunt infection at the Emergency Department and had a pre-diagnosis of ventriculitis. Read More

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http://dx.doi.org/10.1007/s00381-019-04070-xDOI Listing
January 2019

Factors affecting epilepsy prognosis in patients with tuberous sclerosis.

Childs Nerv Syst 2019 Jan 23. Epub 2019 Jan 23.

Department of Biostatistics, Cukurova University, Adana, Turkey.

Purpose: We aimed to determine the characteristics of epileptic seizures that significantly affect the cognitive functions of 83 patients followed with tuberous sclerosis complex (TSC), their resistance to treatment and risk factors causing this resistance.

Materials-methods: In order to determine the prognosis, the seizure-free/seizure-controlled group and the group with refractory seizures were compared. In addition, risk factors affecting cognitive functions in the patients were determined. Read More

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http://link.springer.com/10.1007/s00381-019-04066-7
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http://dx.doi.org/10.1007/s00381-019-04066-7DOI Listing
January 2019
3 Reads

Familial arachnoid cysts: a review of 35 families.

Childs Nerv Syst 2019 Jan 23. Epub 2019 Jan 23.

Department of Neurosurgery, First Hospital of Jilin University, 71, Xinmin Street, Changchun, 130021, Jilin, People's Republic of China.

Introduction: Arachnoid cysts are commonly considered congenital lesions, but this has not been proven. With the development of neuroimaging and DNA testing technology, more cases of familial arachnoid cysts have been reported. Herein, we review such cases. Read More

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http://dx.doi.org/10.1007/s00381-019-04060-zDOI Listing
January 2019
5 Reads

Letter to the editor: citations for the case report on idiopathic hypertrophic pachymeningitis by Kosuke Tsuchida et al.

Authors:
Shi-Jun Li

Childs Nerv Syst 2019 Jan 23. Epub 2019 Jan 23.

Department of Pediatrics, the Second Xiangya Hospital, Central South University, Changsha, 410011, Hunan, China.

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http://dx.doi.org/10.1007/s00381-019-04055-wDOI Listing
January 2019

The life and works of Giulio Cesare Casseri (1552-1616), who was the pioneer neuroanatomist.

Childs Nerv Syst 2019 Jan 23. Epub 2019 Jan 23.

Department of Anatomy, Faculty of Medicine, Gaziantep University, TR-27310, Gaziantep, Turkey.

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http://dx.doi.org/10.1007/s00381-019-04062-xDOI Listing
January 2019
1 Read
1.163 Impact Factor

"Encased brain" in hypertrophic pachymeningitis.

Childs Nerv Syst 2019 Jan 21. Epub 2019 Jan 21.

Pediatric Neurology Unit, Department of Pediatrics, Postgraduate Institute of Medical Education and Research, Chandigarh, 160012, India.

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http://dx.doi.org/10.1007/s00381-019-04061-yDOI Listing
January 2019
1.163 Impact Factor

Erythropoietin protects the subventricular zone and inhibits reactive astrogliosis in kaolin-induced hydrocephalic rats.

Childs Nerv Syst 2019 Jan 19. Epub 2019 Jan 19.

Department of Neurosurgery, Faculty of Medicine Universitas Udayana - Sanglah General Hospital, Denpasar, Indonesia.

Purpose: To elucidate the potential role of erythropoietin (EPO) as a neuroprotective agent against reactive astrogliosis and reducing the thinning rate of subventricular zone (SVZ) in kaolin-induced hydrocephalic rats.

Method: Thirty-six ten-week-old Sprague-Dawley rats were used in this study. Hydrocephalus was induced with 20% kaolin suspension injected into the cistern of thirty rats and leaving the six rats as normal group. Read More

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http://dx.doi.org/10.1007/s00381-019-04063-wDOI Listing
January 2019
1 Read

Lack of association of cranial lacunae with intracranial hypertension in children with Crouzon syndrome and Apert syndrome: a 3D morphometric quantitative analysis.

Childs Nerv Syst 2019 Jan 19. Epub 2019 Jan 19.

Craniofacial Unit, Great Ormond Street Hospital, London, UK.

Purpose: Cranial lacunae (foci of attenuated calvarial bone) are CT equivalents of "copper beating" seen on plain skull radiographs in children with craniosynostosis. The qualitative presence of copper beating has not been found to be useful for the diagnosis of intracranial hypertension (IH) in these patients. 3D morphometric analysis (3DMA) allows a more systematic and quantitative assessment of calvarial attenuation. Read More

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http://dx.doi.org/10.1007/s00381-019-04059-6DOI Listing
January 2019
2 Reads

Cerebellar mutism after posterior fossa tumor resection in children: a multicenter international retrospective study to determine possible modifiable factors.

Childs Nerv Syst 2019 Jan 18. Epub 2019 Jan 18.

Division of Neurosurgery, Department of Surgery, British Columbia Children's Hospital and University of British Columbia, Vancouver, Canada.

Purpose: A preliminary survey of pediatric neurosurgeons working at different centers around the world suggested differences in clinical practice resulting in variation in the risk of pediatric cerebellar mutism (CM) and cerebellar mutism syndrome (CMS) after posterior fossa (PF) tumor resection. The purposes of this study were (1) to determine the incidence and severity of CM and CMS after midline PF tumor resection in children treated at these centers and (2) to identify potentially modifiable factors related to surgical management (rather than tumor biology) that correlate with the incidence of CM/CMS.

Methods: Attending pediatric neurosurgeons at British Columbia's Children's Hospital (BCCH) and neurosurgeons who completed a pediatric neurosurgery fellowship at BCCH were invited to provide data from the center where they currently practiced. Read More

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http://dx.doi.org/10.1007/s00381-019-04058-7DOI Listing
January 2019
2 Reads

Contralateral facial nerve paresis subsequent to posterior fossa meningioma surgery in a child: case report.

Childs Nerv Syst 2019 Jan 15. Epub 2019 Jan 15.

Department of Neurosurgery, Children's Hospital Medical Center, Tehran University of Medical Science, Gharib Street, Tehran, 141557854, Iran.

Introduction: Meningiomas are relatively uncommon neoplasms in the pediatric population and posterior fossa is a very rare location for these tumors. Only a few cases of contralateral cranial nerve deficits have been reported but no cases of pediatric meningioma with contralateral facial nerve paresis have been documented in literature.

Cerebellopontine Angle Meningioma Who Case Report: We present a 4 year old girl with found postoperative contralateral facial nerve paresis. Read More

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http://link.springer.com/10.1007/s00381-019-04053-y
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http://dx.doi.org/10.1007/s00381-019-04053-yDOI Listing
January 2019
3 Reads

Apert syndrome without craniosynostosis.

Childs Nerv Syst 2019 Jan 14. Epub 2019 Jan 14.

Hospital das Clínicas, School of Medicine, University of São Paulo, Street Eneas de Carvalho, 255, Pinheiros, São Paulo, Brazil.

Background: Apert syndrome is a rare form of syndromic craniosynostosis, also known as acrocephalosyndactyly, which is a disorder characterized by a unique set of craniofacial, hand, and foot abnormalities. Diagnosis is made through a genetic analysis, where the mutation of FGFR2, Ser252Trp, and Pro253Arg confirms the diagnosis.

Case Presentation: Although craniosynostosis is the most common characteristic in clinical presentation, we present an atypical case of a one-and-a-half-year-old girl with Apert syndrome confirmed by genetic testing but without craniosynostosis. Read More

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http://dx.doi.org/10.1007/s00381-019-04050-1DOI Listing
January 2019
3 Reads

Pediatric intracranial lower cranial nerve schwannoma unassociated with neurofibromatosis type 2: case report and review of the literature.

Childs Nerv Syst 2019 Jan 13. Epub 2019 Jan 13.

Division of Neurosurgery, National Center for Child Health and Development, Okura 2-10-1, Setagaya-ku, Tokyo, 157-8535, Japan.

Introduction: Pediatric schwannomas are rare, and most of them are associated with neurofibromatosis type 2 (NF2) and usually located in the vestibular nerve. Herein, we present the first pediatric case of intracranial schwannoma derived from the IX/X nerve complex unrelated to NF2.

Case Report: The patient was a 9-year-old boy who presented with a 3-month history of headache and nausea. Read More

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http://dx.doi.org/10.1007/s00381-018-04045-4DOI Listing
January 2019
1 Read

Treatment of multi-loculated hydrocephalus using endoscopic cyst fenestration and endoscopic guided VP shunt insertion.

Childs Nerv Syst 2019 Jan 12. Epub 2019 Jan 12.

Division of Neurosurgery, Department of Surgery, Queen Sirikit National Institute of Child Health, Bangkok, Thailand.

Objective: To evaluate the role of endoscopic cyst fenestration and endoscopic guided VP shunt insertion in multi-loculated hydrocephalus in children.

Method: A retrospective analysis was performed on 20 patients with multi-loculated hydrocephalus who underwent endoscopic cyst fenestration (ECF) alone or in combination with VP shunt revision or insertion between August 2014 and December 2016 with the extended follow-up period to December 2017.

Results: Thirty-one ECFs were performed: ECF alone, 10 operations in 8 cases, and 21 ECFs with shunt insertion in 12 cases. Read More

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http://dx.doi.org/10.1007/s00381-019-04047-wDOI Listing
January 2019
2 Reads

A novel type of C11orf95-LOC-RELA fusion in a grade II supratentorial ependymoma: report of a case with literature review.

Childs Nerv Syst 2019 Jan 10. Epub 2019 Jan 10.

Departments of Pediatrics, Ribeirão Preto Medical of School, University of São Paulo, Ribeirão Preto, SP, Brazil.

Background: Ependymoma (EPN) is the third most common central nervous system tumor in childhood. Recent advances in the molecular classification of EPN revealed a supratentorial (ST) ependymoma subgroup characterized by C11orf95-RELA fusion.

Case Report: We describe a novel RELA-fusion composed by a chimeric transcript C11orf95-LOC-RELA in a supratentorial WHO grade II EPN occurring in a 4-year-old child. Read More

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http://dx.doi.org/10.1007/s00381-018-04028-5DOI Listing
January 2019
1 Read

Magnetic resonance-guided laser interstitial thermal therapy for the treatment of non-lesional insular epilepsy in pediatric patients: thermal dynamic and volumetric factors influencing seizure outcomes.

Childs Nerv Syst 2019 Jan 9. Epub 2019 Jan 9.

Division of Neurosurgery, Children's National Medical Center, George Washington University School of Medicine and Health Sciences, Washington, DC, USA.

Purpose: To investigate the safety and efficacy of stereoelectroencephalography (sEEG) directed magnetic resonance-guided laser interstitial thermal therapy (MRgLITT) in medically refractory insular epilepsy in pediatric patients, define the relationship between ablation volumes and seizure control, and analyze the relationship between thermal energy and ablation volumes.

Methods: A single-institution, retrospective review of pediatric patients with insular epilepsy who underwent sEEG directed MRgLITT over a 10-month period was performed. Perioperative, imaging, and outcome data were analyzed. Read More

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http://dx.doi.org/10.1007/s00381-019-04051-0DOI Listing
January 2019
2 Reads

Use of computed tomography and diffusion weighted imaging in children with ventricular shunt.

Childs Nerv Syst 2019 Jan 8. Epub 2019 Jan 8.

Department of Neurosurgery, Dıskapı Yıldırım Beyazıt Training and Research Hospital, University of Health Sciences, Dıskapı, 06130, Ankara, Turkey.

Purpose: To evaluate the indications, number, and imaging results of brain computed tomography (CT) and diffusion weighted imaging (DWI) in children with ventriculoperitoneal shunt, to estimate the radiation dose, and to evaluate the effectiveness of DWI.

Methods: This retrospectively study included 54 consecutive patients (boys/girls = 30/24, mean age, 3 ± 4.1 years) with shunt that were placed due to congenital abnormalities-hypoxic ischemic encephalopathy between January 2015 and March 2018. Read More

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http://dx.doi.org/10.1007/s00381-018-04046-3DOI Listing
January 2019
6 Reads

Decreased MEPs during subcutaneous dissection for untethering surgery of a "true" lipomyelomeningocele: aggravated traction of the spinal cord by release of the sac from the original nest.

Childs Nerv Syst 2019 Jan 8. Epub 2019 Jan 8.

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, 101 Daehak-ro, Jongno-gu, Seoul, 03080, Republic of Korea.

Purpose: It is well known that the preoperative enlarged sac in occult spinal dysraphism, in which the spinal cord is attached to its dome, can be associated with neurological deficits by aggravation of spinal cord traction. We experienced a similar phenomenon during the early stage of untethering surgery for "lipomyelomeningocele in a strict sense (LMMC)."

Clinical Presentation: We report a case of a 3-month-old girl with LMMC, which showed decreased motor evoked potentials (MEPs) in the lower extremities during the early stage of untethering surgery. Read More

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http://link.springer.com/10.1007/s00381-019-04049-8
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http://dx.doi.org/10.1007/s00381-019-04049-8DOI Listing
January 2019
4 Reads

Medulloepithelioma with heterologous osteoid component: a case report and review of literature.

Childs Nerv Syst 2019 Jan 8. Epub 2019 Jan 8.

Department of Pathology and Laboratory Medicine, King Hussein Cancer Center (KHCC), 202 Queen Rania Street, P.O. Box 1269 Al-Jubeiha, Amman, 11941, Jordan.

Purpose: Medulloepithelioma is a rare brain tumor that has been classified as embryonal tumor with multilayered rosettes (ETMR) if it harbors C19MC amplification. In rare instances, it shows evidence of heterologous differentiation.

Methods: We report a case of a 10-year-old female who presented with headache, squint, and minimal left sided weakness of 1 week duration. Read More

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http://link.springer.com/10.1007/s00381-018-04041-8
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http://dx.doi.org/10.1007/s00381-018-04041-8DOI Listing
January 2019
2 Reads

Intracranial volume (ICV) in isolated sagittal craniosynostosis: a retrospective case-matched-control study.

Childs Nerv Syst 2019 Jan 7. Epub 2019 Jan 7.

Craniofacial Unit, Birmingham Children's Hospital, Birmingham, UK.

Purpose: Children with sagittal craniosynostosis (SC) are at risk of developing raised intracranial pressure (ICP). This is thought to result from cephalocranial disproportion-the restriction of normal cerebral development by a small cranial vault. It remains unclear whether intracranial volume (ICV) is altered in SC. Read More

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http://link.springer.com/10.1007/s00381-018-4018-0
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http://dx.doi.org/10.1007/s00381-018-4018-0DOI Listing
January 2019
3 Reads

The interhemispheric approach in children: our experience and review of the literature.

Childs Nerv Syst 2019 Jan 7. Epub 2019 Jan 7.

Departments of Neurosurgery and Pediatric Neurosurgery, Tel-Aviv Sourasky Medical Center and Dana Children's Hospital Tel Aviv, Tel Aviv University, 6 Weizmann Street, Tel Aviv, Israel.

Objective: The interhemispheric approach (IA) has been extensively described for treating pathologies located at the lateral or third ventricle, pineal region, and periventricular locations. While these anatomical locations are the target of many pediatric pathologies, very few series have analyzed the morbidity and outcome of the IA in children. The aim of this study is to describe our experience using the IA in children, emphasizing the approach-related morbidity. Read More

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http://dx.doi.org/10.1007/s00381-018-04039-2DOI Listing
January 2019
2 Reads

Additional squamosal suture synostosis and segmented intracranial volume in patients with non-syndromic sagittal synostosis.

Childs Nerv Syst 2019 Feb 7;35(2):205-207. Epub 2019 Jan 7.

Department of Plastic Surgery, University of Helsinki and Helsinki University Hospital, Helsinki, Finland.

Purpose: To evaluate the incidence of squamosal suture synostosis (SQS) in children with non-syndromic sagittal synostosis and to evaluate whether the additional SQS affects the intracranial volume (ICV).

Methods: Thirty-four consecutive patients (23 boys) who had been operated by cranial vault remodelling because of sagittal synostosis were compared retrospectively from 3D-CT imaging data sets obtained from volumetric CT. The mean age of the patients at preoperative CT imaging was 0. Read More

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http://dx.doi.org/10.1007/s00381-018-04029-4DOI Listing
February 2019
1 Read

Tectocerebellar dysraphia with occipital encephalocele: a phenotypic variant of the TMEM231 gene mutation induced Joubert syndrome.

Childs Nerv Syst 2019 Jan 7. Epub 2019 Jan 7.

Division of Neurosurgery, Department of Neurosciences, King Faisal Specialist Hospital and Research Centre, Al Zahrawi Street, Riyadh, 11211, Saudi Arabia.

There are few reported cases of tectocerebellar dysraphia with occipital encephalocele (TCD-OE) in the literature. This malformation was first described by Padget and Lindburg in 1972 and consists of an occipital encephalocele, a cerebellar midline defect, inverted cerebellum, and deformity of the tectum. Occurrence is believed to be sporadic with a male predominance and a usually poor prognosis. Read More

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http://link.springer.com/10.1007/s00381-019-04048-9
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http://dx.doi.org/10.1007/s00381-019-04048-9DOI Listing
January 2019
4 Reads

A rare cause of scalp swelling in infancy: delayed subaponeurotic fluid collections in five cases.

Childs Nerv Syst 2019 Jan 7. Epub 2019 Jan 7.

Division of Pediatric Infectious Diseases, Department of Pediatrics, Ankara University School of Medicine, Cebeci Hospital, 06590, Ankara, Turkey.

Subaponeurotic (subgaleal) fluid collection (DSFC) is a rare clinical entity of unknown etiology. We aimed to present our series of infants who were diagnosed with DSCF at Ankara University Children's Hospital. We retrospectively reviewed clinical findings, imaging studies, laboratory tests, management, and clinical courses of infants diagnosed with DSCF between June 2014 and June 2018. Read More

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http://link.springer.com/10.1007/s00381-018-04040-9
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http://dx.doi.org/10.1007/s00381-018-04040-9DOI Listing
January 2019
16 Reads

Interdural high signal on CISS sequence: an alternative CSF pathway?

Childs Nerv Syst 2019 Jan 6. Epub 2019 Jan 6.

Department of Neurological Surgery, Juntendo University Urayasu Hospital, 2-1-1 Tomioka, Urayasu, Chiba, 279-0021, Japan.

Purpose: The falx cerebri, falx cerebelli, and tentorial notch exhibit a peculiar morphology with a two-layered, dural leaf that protrudes into the cranial cavity with a free edge. However, there are few studies exploring this morphology using neuroimaging techniques. The present study aimed to explore these dural structures using magnetic resonance imaging. Read More

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http://link.springer.com/10.1007/s00381-018-04044-5
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http://dx.doi.org/10.1007/s00381-018-04044-5DOI Listing
January 2019
2 Reads

The first Korean case report with scaphocephaly as the initial sign of X-linked hypophosphatemic rickets.

Childs Nerv Syst 2019 Jan 6. Epub 2019 Jan 6.

Division of Pediatric Neurology, Department of Pediatrics, Busan Paik Hospital, Inje University College of Medicine, Bokji-ro 75, Busanjin-gu, Busan, 47392, South Korea.

Introduction: X-linked hypophosphatemic rickets (XLH) can occasionally cause premature fusion of cranial sutures through an increased level of fibroblast growth factor 23 (FGF-23), which leads to the dysregulation of phosphate and vitamin D metabolism. Secondary craniosynostosis has long been considered to present late after XLH has already been diagnosed either clinically or genetically.

Case Presentation: We present observations of a male infant showing sagittal synostosis as the first sign of XLH. Read More

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http://dx.doi.org/10.1007/s00381-018-04042-7DOI Listing
January 2019
1 Read

Sodium fluorescein-guided brain tumor surgery under the YELLOW-560-nm surgical microscope filter in pediatric age group: feasibility and preliminary results.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Department of Neurosurgery, Liv Hospital Ulus, Istanbul, Turkey.

Objective: To evaluate the feasibility and safety of sodium fluorescein (Na-Fl)-guided surgery with the use of the PENTERO 900 surgical microscope (Carl Zeiss, Meditec, Oberkochen, Germany) equipped with the YELLOW-560-nm filter and low-dose Na-Fl (2 mg/kg) in pediatric brain tumor surgery.

Methods: The study included 23 pediatric patients with various intracranial pathologies, who underwent Na-Fl-guided surgery between April 2015 and February 2018. Clinical features, surgical observations, extent of resection, and tumor histopathology were retrospectively analyzed. Read More

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http://dx.doi.org/10.1007/s00381-018-04037-4DOI Listing
January 2019
1 Read

Patterns, treatments, and outcomes of pediatric central nervous system tumors in Sudan: a single institution experience.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Department of Global Pediatric Medicine, St. Jude Children's Research Hospital, Memphis, TN, USA.

Purpose: Studies of epidemiology, treatment modalities, and outcomes of childhood central nervous system (CNS) tumors in Sudan are scarce. To address this shortcoming, we evaluated baseline information about the epidemiology, treatment types, and outcomes of childhood CNS tumors at the National Cancer Institute, University of Gezira (NCI-UG) in Wad Madani, Sudan.

Methods: We performed a retrospective health facility-based study of children with CNS tumors who were treated at the NCI-UG from January 2000 to December 2015. Read More

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http://link.springer.com/10.1007/s00381-018-04032-9
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http://dx.doi.org/10.1007/s00381-018-04032-9DOI Listing
January 2019
4 Reads

Thanatophoric dysplasia type 1 with tectal plate dysplasia and aqueductal stenosis.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Department of Radiology, Queen's Hospital, Rom Valley Way, Romford, RM7 0AG, UK.

Introduction: Skeletal dysplasias are a heterogeneous group of disorders comprising of more than 300 entities, many of which manifest in the prenatal period, emphasizing the importance of accurate prenatal diagnosis. Detection of a lethal skeletal dysplasia via prenatal ultrasound is often straightforward. However, establishing the specific diagnosis and detailed evaluation of intracranial anomalies are often challenging. Read More

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http://dx.doi.org/10.1007/s00381-018-04035-6DOI Listing
January 2019
2 Reads

Georges Charles Guillain (1876-1961) and Pierre Mollaret (1898-1987) and their legacy to neuroanatomy: the forgotten triangle of Guillain-Mollaret.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Department of Neurosurgery, Adnan Menderes University School of Medicine, Aydın, Turkey.

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http://dx.doi.org/10.1007/s00381-018-04033-8DOI Listing
January 2019
1 Read

Long-term follow-up of myelomeningocele defect closure with dorsal intercostal artery perforator propeller flaps.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Unit of Pediatric Neurosurgery, University Hospital La Fe, Valencia, Spain.

Background: Closure of the skin defect in myelomeningocele repair determines the quality of the surgical result. In large myelomeningoceles, the direct closure or by skin undermining may not be possible. In these cases, the skin defect must be closed using flaps to provide a tension-free and successful closure. Read More

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http://dx.doi.org/10.1007/s00381-018-04030-xDOI Listing
January 2019
2 Reads

Clinically practical formula for preoperatively estimating the cutting rate of the spinal nerve root in a functional posterior rhizotomy.

Authors:
Nobuhito Morota

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Division of Neurosurgery, Tokyo Metropolitan Children's Medical Center, 2-8-29 Musashi-Dai, Fuchu, Tokyo, 183-8561, Japan.

Objective: A functional posterior rhizotomy (FPR) ideally involves minimal cutting of the posterior root while providing maximal reduction of disabling spasticity. However, the ideal cutting rate has yet to be determined. It was hypothesized that the cutting rate of the posterior root would negatively correlate with preoperative motor function in children with spasticity. Read More

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http://link.springer.com/10.1007/s00381-018-04027-6
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http://dx.doi.org/10.1007/s00381-018-04027-6DOI Listing
January 2019
2 Reads

Neurocognitive profile in children with arachnoid cysts before and after surgical intervention.

Childs Nerv Syst 2019 Jan 4. Epub 2019 Jan 4.

Division of Pediatric Neurosurgery, Seoul National University Children's Hospital, Seoul, Republic of Korea.

Objectives: Treatment indications for arachnoid cysts are not clear. Some surgeons take improvement in neurocognitive function into account as a surgical indication for arachnoid cysts. However, only a few studies have evaluated the relationship between arachnoid cysts and neurocognitive function. Read More

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http://dx.doi.org/10.1007/s00381-018-4026-0DOI Listing
January 2019
2 Reads

Outcomes from primary surgical reconstruction of neonatal brachial plexus palsy in 104 children.

Childs Nerv Syst 2019 Feb 4;35(2):349-354. Epub 2019 Jan 4.

Peripheral Nerve Surgery Unit, Department of Neurosurgery, University of São Paulo Medical School, São Paulo, SP, Brazil.

Purpose: The outcome from microsurgical reconstruction of neonatal brachial plexus palsy (NBPP) varies, and comparison between different series is difficult, given the differences in preoperative evaluation, surgical strategies, and outcome analysis. To evaluate our results, we reviewed a series of children who underwent surgical treatment in a period of 14 years.

Methods: We made a retrospective review of 104 cases in which microsurgical repair of the brachial plexus was performed. Read More

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http://link.springer.com/10.1007/s00381-018-04036-5
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http://dx.doi.org/10.1007/s00381-018-04036-5DOI Listing
February 2019
5 Reads