26,677 results match your criteria Chiang Mai Journal Of Science[Journal]


Handedness and Birth Order Among Heterosexual Men, Gay Men, and Sao Praphet Song in Northern Thailand.

Arch Sex Behav 2020 Jul 5. Epub 2020 Jul 5.

Department of Psychology, University of Toronto Mississauga, 3359 Mississauga Road North, Mississauga, ON, L5L 1C6, Canada.

Previous research has examined handedness and birth order to inform sexual orientation and gender identity/role expression development; however, sexual orientation and gender identity/role expression have rarely been disentangled to provide a more nuanced perspective. In Thailand, we investigated sexual orientation and gender identity simultaneously via comparison of 282 heterosexual men, 201 gay men, and 178 sao praphet song-i.e. Read More

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http://dx.doi.org/10.1007/s10508-020-01774-zDOI Listing

Metformin Preferentially Provides Neuroprotection Following Cardiac Ischemia/Reperfusion in Non-Diabetic Rats.

Biochim Biophys Acta Mol Basis Dis 2020 Jul 1:165893. Epub 2020 Jul 1.

Cardiac Electrophysiology Research and Training Center, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200, Thailand; Center of Excellence in Cardiac Electrophysiology Research, Chiang Mai University, Chiang Mai, 50200, Thailand; Department of Oral Biology and Diagnostic Sciences, Faculty of Dentistry, Chiang Mai University, Chiang Mai, 50200, Thailand. Electronic address:

Following acute myocardial infarction, re-establishment of coronary perfusion aggravates further injuries in the heart and remote organs including the brain as a consequence of ischemia/reperfusion (I/R) injury. Since pretreatment with metformin attenuated both cardiac and cerebral I/R injury via AMP-activated protein kinase (AMPK) pathways, we hypothesized that metformin given after ischemia mitigates both cardiac and brain pathologies following cardiac I/R. Male Wistar rats were subjected to either cardiac I/R (30 min-ischemia/120 min-reperfusion; n=30) or sham operation (n=5). Read More

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http://dx.doi.org/10.1016/j.bbadis.2020.165893DOI Listing

Cloning and promoter analysis of palladin 90-kDa, 140-kDa, and 200-kDa isoforms involved in skeletal muscle cell maturation.

BMC Res Notes 2020 Jul 3;13(1):321. Epub 2020 Jul 3.

Department of Life Sciences, College of Biosciences and Biotechnology, National Cheng Kung University, No. 1 University Road, East Dist.,, Tainan City, 701, Taiwan (R.O.C.).

Objective: Palladin is a ubiquitous phosphoprotein expressed in vertebrate cells that works as a scaffolding protein. Several isoforms deriving from alternative splicing are originated from the palladin gene and involved in mesenchymal and muscle cells formation, maturation, migration, and contraction. Recent studies have linked palladin to the invasive spread of cancer and myogenesis. Read More

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http://dx.doi.org/10.1186/s13104-020-05152-9DOI Listing

(-)-Kusunokinin inhibits breast cancer in N-nitrosomethylurea-induced mammary tumor rats.

Eur J Pharmacol 2020 Jun 30:173311. Epub 2020 Jun 30.

Department of Biomedical Sciences, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand; The Excellent Research Laboratory of Cancer Molecular Biology, Prince of Songkla University, Hat Yai, Songkhla, 90110, Thailand. Electronic address:

Natural and synthetic (-)-kusunokinin inhibited breast cancer, colon cancer and cholangiocarcinoma cells at the G2/M phase and induced apoptosis. However, there is no report on the action and adverse effects of (-)-kusunokinin in animal models. In this study, we investigated the cytotoxic effect of (-)-kusunokinin from Piper nigrum on cancer cells. Read More

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http://dx.doi.org/10.1016/j.ejphar.2020.173311DOI Listing

Matriptase and prostasin proteolytic activities are differentially regulated in normal and wounded skin.

Hum Cell 2020 Jul 2. Epub 2020 Jul 2.

Lombardi Comprehensive Cancer Center, Department of Oncology, Georgetown University, W412 Research Building, 3970 Reservoir Road NW, Washington, DC, 20057, USA.

Orchestrated control of multiple overlapping and sequential processes is required for the maintenance of epidermal homeostasis and the response to and recovery from a variety of skin insults. Previous studies indicate that membrane-associated serine protease matriptase and prostasin play essential roles in epidermal development, differentiation, and barrier formation. The control of proteolysis is a highly regulated process, which depends not only on gene expression but also on zymogen activation and the balance between protease and protease inhibitor. Read More

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http://dx.doi.org/10.1007/s13577-020-00385-zDOI Listing

Assessment of Cd(II) adsorption capability and mechanism from aqueous phase using virgin and calcined lignin.

Heliyon 2020 Jun 25;6(6):e04298. Epub 2020 Jun 25.

Faculty of Pharmacy, Kindai University, 3-4-1 Kowakae, Higashi-Osaka, Osaka, 577-8502, Japan.

Herein, to assess the adsorption capability and elucidate the adsorption mechanism of Cd(II) from the aqueous phase, virgin lignin (Lig) and calcined lignin (Lig200, Lig400, Lig600, Lig800, and Lig1000) were prepared. The characteristics, including specific surface area and pore volume of adsorbents, were investigated, and the adsorption capability along with the effect of temperature, contact time, and pH on the adsorption of Cd(II) were evaluated. The characteristics of the adsorbent surface were related to the adsorption capability of Cd(II) from the aqueous phase, and the correlation coefficients between the adsorbed amount and specific surface area and total pore volumes were 0. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04298DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322691PMC

Earthquake statistics changed by typhoon-driven erosion.

Sci Rep 2020 Jul 2;10(1):10899. Epub 2020 Jul 2.

Helmholtz Centre Potsdam, German Research Center for Geosciences (GFZ), 14473, Potsdam, Germany.

Tectonics and climate-driven surface processes govern the evolution of Earth's surface topography. Topographic change in turn influences lithospheric deformation, but the elementary scale at which this feedback can be effective is unclear. Here we show that it operates in a single weather-driven erosion event. Read More

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http://dx.doi.org/10.1038/s41598-020-67865-yDOI Listing

Application of machine learning algorithm and modified high resolution DNA melting curve analysis for molecular subtyping of Salmonella isolates from various epidemiological backgrounds in northern Thailand.

World J Microbiol Biotechnol 2020 Jul 2;36(7):103. Epub 2020 Jul 2.

Division of Biochemistry, School of Medical Sciences, University of Phayao, 19 Moo 2, Tambon Maeka, Amphur Muang, Phayao, 56000, Thailand.

Food poisoning from consumption of food contaminated with non-typhoidal Salmonella spp. is a global problem. A modified high resolution DNA melting curve analysis (m-HRMa) was introduced to provide effective discrimination among closely related HRM curves of amplicons generated from selected Salmonella genome sequences enabled Salmonella spp. Read More

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http://dx.doi.org/10.1007/s11274-020-02874-7DOI Listing

Prevalence of and factors associated with depression among hill tribe individuals aged 30 years and over in Thailand.

Heliyon 2020 Jun 23;6(6):e04273. Epub 2020 Jun 23.

Center of Excellence for the Hill Tribe Health Research, Mae Fah Luang University, Chiang Rai, Thailand.

Background: Depression is a silent health problem that can lead to severe and sometimes fatal outcomes if individuals are not diagnosed and treated properly; this is particularly true in populations with limited education, low economic status and several barriers to accessing health services, such as the hill tribe people in Thailand.

Methods: This cross-sectional study aimed to explore the prevalence of and factors associated with depression among hill tribe individuals aged 30 years and over. A validated questionnaire and the Patient Health Questionnaire-9 (PHQ-9) were used for data collection in an interview format in a private and confidential room. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04273DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322052PMC

Bats and belief: A sequential qualitative study in Thailand.

Heliyon 2020 Jun 20;6(6):e04208. Epub 2020 Jun 20.

Center of Excellence for Emerging and Re-emerging Infectious Diseases in Animals, Faculty of Veterinary Science, Chulalongkorn University, Bangkok, Thailand.

Bats are wildlife and distribute globally. In Thailand, there are hundreds of bat species in different locations within four regions. However, few motivations and influences for having contact with bats have been documented. Read More

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http://dx.doi.org/10.1016/j.heliyon.2020.e04208DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7322253PMC

Caspase dependent apoptosis is required for anterior regeneration in Aeolosoma viride and its related gene expressions are regulated by the Wnt signaling pathway.

Sci Rep 2020 Jul 1;10(1):10692. Epub 2020 Jul 1.

National Taiwan University, Department of Life Science, Taipei city, 10672, Taiwan.

Although apoptosis has been widely observed during the regenerative process, the mechanisms by which it is regulated and its roles in regeneration remained unclear. In this study, we introduced Aeolosoma viride, a fresh water annelid with an extraordinary regenerative ability as our model organism to study the functions and regulations of apoptotic caspases. Here we showed that major events of apoptosis were detected near the wounded area and showed spatial correlation with the expression patterns of caspase gene namely Avi-caspase X and two apoptosis regulators namely Avi-Bax and Avi-Bcl-xL. Read More

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http://dx.doi.org/10.1038/s41598-020-64008-1DOI Listing

Flavanones from the Twigs and Barks of Artocarpus lakoocha Having Antiplasmodial and Anti-TB Activities.

Chem Pharm Bull (Tokyo) 2020 ;68(7):671-674

Department of Chemistry and Center of Excellence for Innovation in Chemistry, Faculty of Science, Chiang Mai University.

Chromatographic separation of the acetone extracts from the twigs and barks of Artocarpus lakoocha led to the isolation of the one new flavanone, lakoochanone (1), together with eleven known compounds (2-12). Lakoochanone (1) and moracin C (4) exhibited weak antiplasmodial activity against Plasmodium falciparum Dd2 with IC values of 36.7 and 33. Read More

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http://dx.doi.org/10.1248/cpb.c20-00080DOI Listing
January 2020

Clinical application of target temperature management in children with acute encephalopathy-A practical review.

Biomed J 2020 Jun 28. Epub 2020 Jun 28.

Division of Pediatric Neurology, Chang Gung Children's Hospital at Linkou, Taoyuan, Taiwan; College of Medicine, Chang Gung University, Taoyuan, Taiwan. Electronic address:

Acute encephalopathy is a life-threatening disease involving acute brain dysfunction, and it is one of the most important causes of mortality and severe neurological sequelae in infants and children. Approximately 30% of cases of acute encephalopathy result in some degree of neurological sequelae. Although many strategies have been proposed, effective therapies to ameliorate the outcomes of acute encephalopathy have not yet been established. Read More

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http://dx.doi.org/10.1016/j.bj.2019.12.003DOI Listing

A modified self-tuning fuzzy logic temperature controller for metal induction heating.

Rev Sci Instrum 2020 Jun;91(6):064905

Department of Electrical Engineering, National Cheng Kung University, Tainan City 70101, Taiwan.

This paper presents a method to build a dynamic target curve producer corresponding to the rising time setting and the ultimate target temperature as a reference for a fuzzy logic controller that is used in the metal heating process application. To achieve this goal, there are some quantization factors in a fuzzy controller that must be set according to the system situation, as well as the experience of experts that will cause the controller to have a lack of adaptivity. To solve this problem, in this paper, all the quantization factors are analyzed thoroughly, and a self-tuning module is designed to make it possible for the controller to perform real-time adjustments based on the system situation and, eventually, make it more adaptive. Read More

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http://dx.doi.org/10.1063/5.0006019DOI Listing

Ethnomedicinal Plant Knowledge of the Karen in Thailand.

Plants (Basel) 2020 Jun 29;9(7). Epub 2020 Jun 29.

Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.

The Thai Karen, the largest hill-tribe in Thailand, guard substantial ethnomedicinal plant knowledge, as documented in several studies that targeted single villages. Here, we have compiled information from all the reliable and published sources to present a comprehensive overview of the Karen ethnomedicinal plant knowledge. Our dataset covers 31 Karen villages distributed over eight provinces in Thailand. Read More

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http://dx.doi.org/10.3390/plants9070813DOI Listing

Effects of Parental Warmth and Behavioral Control on Adolescent Externalizing and Internalizing Trajectories Across Cultures.

J Res Adolesc 2020 Jul 1. Epub 2020 Jul 1.

University of Naples "Federico II".

We investigated the effects of parental warmth and behavioral control on externalizing and internalizing symptom trajectories from ages 8 to 14 in 1,298 adolescents from 12 cultural groups. We did not find that single universal trajectories characterized adolescent externalizing and internalizing symptoms across cultures, but instead found significant heterogeneity in starting points and rates of change in both externalizing and internalizing symptoms across cultures. Some similarities did emerge. Read More

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http://dx.doi.org/10.1111/jora.12566DOI Listing

Effect of Insurance Type on Stage at Presentation, Surgical Approach, Tumor Recurrence and Cancer-Specific Survival in Resectable Non-Small Lung Cancer Patients.

Risk Manag Healthc Policy 2020 12;13:559-569. Epub 2020 Jun 12.

Department of Surgery, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Purpose: The aim of this study was to identify the association between Thailand's insurance types and stage at presentation, surgical approach, tumor recurrence and cancer-specific survival in resectable non-small cell lung cancer (NSCLC) patients in northern Thailand.

Patients And Methods: Medical records of patients with NSCLC who underwent pulmonary resection at Chiang Mai University Hospital from January 2007 through December 2015 were retrospectively reviewed. Patients were divided into two groups: patients with the Universal Coverage Scheme (UCS) or Social Security Scheme (SSS) and patients with the Civil Servant Medical Benefit Scheme (CSMBS) or private insurance (PI). Read More

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http://dx.doi.org/10.2147/RMHP.S244344DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297449PMC

Comparison of Two Tube-Modification Techniques in Baerveldt Glaucoma Implantation in Refractory Glaucoma.

Clin Ophthalmol 2020 19;14:1689-1695. Epub 2020 Jun 19.

Department of Ophthalmology, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Importance: To compare treatment outcomes among a stent group, ligature group and combined group in eyes with refractory glaucoma.

Background: Various techniques have been used intra-operatively to restrict the aqueous flow in Baerveldt glaucoma implantation.

Design: Retrospective chart review. Read More

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http://dx.doi.org/10.2147/OPTH.S246905DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7311164PMC

decreases asthma exacerbations and modulates respiratory syncytial virus latent infection in children.

Thorax 2020 Jun 30. Epub 2020 Jun 30.

Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan

Background: Respiratory syncytial virus (RSV) is associated with childhood asthma. Nevertheless, not all children exposed to RSV develop asthma symptoms, possibly because genes modulate the effects of RSV on asthma exacerbations.

Objective: The purpose of this study was to identify genes that modulate the effect of RSV latent infection on asthma exacerbations. Read More

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http://dx.doi.org/10.1136/thoraxjnl-2019-214132DOI Listing

Medicinal Plants for Treating Musculoskeletal Disorders among Karen in Thailand.

Plants (Basel) 2020 Jun 28;9(7). Epub 2020 Jun 28.

Department of Biology, Faculty of Science, Chiang Mai University, Chiang Mai 50200, Thailand.

Millions of people suffer from Musculoskeletal System Disorders (MSDs), including Karen people who work hard in the fields for their subsistence and have done so for generations. This has forced the Karen to use many medicinal plants to treat MSDs. We gathered data from 15 original references covering 27 Karen communities and we document 461 reports of the use of 175 species for treating MSDs among the Karen people in Thailand. Read More

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http://dx.doi.org/10.3390/plants9070811DOI Listing

Antioxidant and Moisturizing Properties of Carboxymethyl Chitosan with Different Molecular Weights.

Polymers (Basel) 2020 Jun 28;12(7). Epub 2020 Jun 28.

Faculty of Agro-Industry, Chiang Mai University, Chiang Mai 50100, Thailand.

This research aimed to synthesize carboxymethyl chitosan (CMCH) from different molecular weights of chitosan including low MW (L, 50-190 kDa), medium MW (M, 210-300 kDa) and high MW (H, 310-375 kDa) on the antioxidant and moisturizing properties. The L-CMCH, M-CMCH and H-CMCH improved the water solubility by about 96%, 90% and 89%, respectively when compared to native chitosan. Higher MW resulted in more viscous of CMCH. Read More

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http://dx.doi.org/10.3390/polym12071445DOI Listing

Development and Characterization of a Fucoidan-Based Drug Delivery System by Using Hydrophilic Anticancer Polysaccharides to Simultaneously Deliver Hydrophobic Anticancer Drugs.

Biomolecules 2020 Jun 28;10(7). Epub 2020 Jun 28.

Department of Materials Science and Engineering, National Chiao Tung University, Hsinchu 30010, Taiwan.

Fucoidan, a natural sulfated polysaccharide, which can activate the immune response and lessen adverse effects, is expected to be an adjuvant agent in combination with chemotherapy. Using natural hydrophilic anticancer polysaccharides to simultaneously encapsulate hydrophobic anticancer drugs is feasible, and a reduced side effect can be achieved to amplify the therapeutic efficacy. In this study, a novel type of fucoidan-PLGA nanocarrier (FPN-DTX) was developed for the encapsulation of the hydrophobic anticancer drug, docetaxel (DTX), as a drug delivery system. Read More

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http://dx.doi.org/10.3390/biom10070970DOI Listing

Production of Lactic Acid from Carob, Banana and Sugarcane Lignocellulose Biomass.

Molecules 2020 Jun 27;25(13). Epub 2020 Jun 27.

Leibniz Institute for Agricultural Engineering and Bioeconomy, Max-Eyth-Allee 100, 14469 Potsdam, Germany.

Lignocellulosic biomass from agricultural residues is a promising feedstock for lactic acid (LA) production. The aim of the current study was to investigate the production of LA from different lignocellulosic biomass. The LA production from banana peduncles using strain with yeast extract resulted in 26. Read More

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http://dx.doi.org/10.3390/molecules25132956DOI Listing

Clinical Detection of Chronic Rhinosinusitis through Next-Generation Sequencing of the Oral Microbiota.

Microorganisms 2020 Jun 26;8(6). Epub 2020 Jun 26.

Department of Medical Laboratory Sciences and Biotechnology, Fooyin University, Kaohsiung 83102, Taiwan.

Chronic rhinosinusitis (CRS) is the chronic inflammation of the sinus cavities of the upper respiratory tract, which can be caused by a disrupted microbiome. However, the role of the oral microbiome in CRS is not well understood. Polymicrobial and anaerobic infections of CRS frequently increased the difficulty of cultured and antibiotic therapy. Read More

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http://dx.doi.org/10.3390/microorganisms8060959DOI Listing

Irukandji-like syndrome caused by single-tentacle box jellyfish found in Thailand, 2007-2019.

Int Marit Health 2020 ;71(2):91-96

Department of Community Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, 50200 Chiang Mai, Thailand.

Background: Irukandji syndrome definition is still widely misunderstood. Irukandji-like syndrome is more unclear than Irukandji syndrome. This study aimed to describe Irukandji-like syndrome in cases involving stinging by single-tentacle box jellyfish species in Thailand. Read More

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http://dx.doi.org/10.5603/IMH.2020.0017DOI Listing
January 2020

Massive Suppression of Proximity Pairing in Topological (Bi_{1-x}Sb_{x})_{2}Te_{3} Films on Niobium.

Phys Rev Lett 2020 Jun;124(23):236402

Department of Physics, University of Illinois at Urbana-Champaign, Urbana, Illinois 61801, USA.

Interfacing bulk conducting topological Bi_{2}Se_{3} films with s-wave superconductors initiates strong superconducting order in the nontrivial surface states. However, bulk insulating topological (Bi_{1-x}Sb_{x})_{2}Te_{3} films on bulk Nb instead exhibit a giant attenuation of surface superconductivity, even for films only two layers thick. This massive suppression of proximity pairing is evidenced by ultrahigh-resolution band mappings and by contrasting quantified superconducting gaps with those of heavily n-doped topological Bi_{2}Se_{3}/Nb. Read More

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http://dx.doi.org/10.1103/PhysRevLett.124.236402DOI Listing

Macular Thickness in Intermediate Age-Related Macular Degeneration Is Influenced by Disease Severity and Subretinal Drusenoid Deposit Presence.

Invest Ophthalmol Vis Sci 2020 Jun;61(6):59

.

Purpose: To investigate how macular thickness varies with intermediate age-related macular degeneration (iAMD) severity and the presence of subretinal drusenoid deposits (SDDs).

Methods: A longitudinal prospective study of 143 participants >50 years of age with no to intermediate AMD who were followed with multimodal imaging and functional testing. Participants were stratified by iAMD severity according to imaging features. Read More

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http://dx.doi.org/10.1167/iovs.61.6.59DOI Listing

Evaluation of a pre-exposure prophylaxis programme for men who have sex with men and transgender women in Thailand: learning through the HIV prevention cascade lens.

J Int AIDS Soc 2020 Jun;23 Suppl 3:e25540

Thai Red Cross AIDS Research Centre, PREVENTION, Bangkok, Thailand.

Introduction: Men who have sex with men (MSM) and transgender women (TGW) are two key populations (KPs) in Thailand at high risk for HIV. Uptake and scale-up of pre-exposure prophylaxis (PrEP) among them has been slow. We used data from Princess PrEP, Thailand's largest KP-led PrEP programme, to operationalize PrEP service cascades. Read More

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http://dx.doi.org/10.1002/jia2.25540DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325508PMC

Development of a Computerized Adaptive Testing System for Assessing Social Knowledge in People With Schizophrenia.

Am J Occup Ther 2020 Jul/Aug;74(4):7404205050p1-7404205050p9

Ching-Lin Hsieh, PhD, OTR, is Professor, School of Occupational Therapy, College of Medicine, National Taiwan University, and Department of Physical Medicine and Rehabilitation, National Taiwan University Hospital, Taipei, Taiwan;

Importance: A psychometrically sound measure of social knowledge (SK) is necessary to assess people with schizophrenia because they tend to have moderate to severe deficits in SK.

Objective: To develop a computerized adaptive test (CAT) for assessing SK in people with schizophrenia.

Design: Two phases, consisting of (1) development and validation of an SK item bank and (2) determination of the best stopping rules for the CAT. Read More

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http://dx.doi.org/10.5014/ajot.2020.036293DOI Listing

Laser interstitial thermal therapy (LITT) vs. bevacizumab for radiation necrosis in previously irradiated brain metastases.

J Neurooncol 2020 Jun 29. Epub 2020 Jun 29.

Department of Neurosurgery, Yale University School of Medicine, 333 Cedar St, New Haven, CT, 06520, USA.

Purpose: Both laser interstitial thermal therapy (LITT) and bevacizumab have been used successfully to treat radiation necrosis (RN) after radiation for brain metastases. Our purpose is to compare pre-treatment patient characteristics and outcomes between the two treatment options.

Methods: Single-institution retrospective chart review identified brain metastasis patients who developed RN between 2011 and 2018. Read More

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http://dx.doi.org/10.1007/s11060-020-03570-0DOI Listing
June 2020
3.070 Impact Factor

In situ electrochemical generation of nitric oxide for neuronal modulation.

Nat Nanotechnol 2020 Jun 29. Epub 2020 Jun 29.

Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, MA, USA.

Understanding the function of nitric oxide, a lipophilic messenger in physiological processes across nervous, cardiovascular and immune systems, is currently impeded by the dearth of tools to deliver this gaseous molecule in situ to specific cells. To address this need, we have developed iron sulfide nanoclusters that catalyse nitric oxide generation from benign sodium nitrite in the presence of modest electric fields. Locally generated nitric oxide activates the nitric oxide-sensitive cation channel, transient receptor potential vanilloid family member 1 (TRPV1), and the latency of TRPV1-mediated Ca responses can be controlled by varying the applied voltage. Read More

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http://dx.doi.org/10.1038/s41565-020-0701-xDOI Listing

Colonic obstruction in a tetraplegic patient: a common symptom from an uncommon cause.

Spinal Cord Ser Cases 2020 Jun 29;6(1):53. Epub 2020 Jun 29.

Department of Rehabilitation Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand.

Introduction: It is difficult to diagnose an acute abdomen condition in people with spinal cord injury due to abnormal sensation below the injured level and multiple co-morbidities. These issues can mislead the exact diagnosis and delay proper treatment.

Case Presentation: A 57-year-old male with C4 AIS C tetraplegia developed nausea and vomiting, abdominal distension and feeding intolerance. Read More

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http://dx.doi.org/10.1038/s41394-020-0305-6DOI Listing

Potential enhancement of host immunity and anti-tumor efficacy of nanoscale curcumin and resveratrol in colorectal cancers by modulated electro- hyperthermia.

BMC Cancer 2020 Jun 29;20(1):603. Epub 2020 Jun 29.

Department of Veterinary Medicine, School of Veterinary Medicine, National Taiwan University, 1 Sec 4 Roosevelt Road, Taipei, 10617, Taiwan.

Background: Modulated electro-hyperthermia (mEHT) is a form of hyperthermia used in cancer treatment. mEHT has demonstrated the ability to activate host immunity by inducing the release of heat shock proteins, triggering apoptosis, and destroying the integrity of cell membranes to enhance cellular uptake of chemo-drugs in tumor cells. Both curcumin and resveratrol are phytochemicals that function as effective antioxidants, immune activators, and potential inhibitors of tumor development. Read More

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http://dx.doi.org/10.1186/s12885-020-07072-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7324975PMC

Factors associated with quality of life among chronic kidney disease patients in Nepal: a cross-sectional study.

Health Qual Life Outcomes 2020 Jun 29;18(1):207. Epub 2020 Jun 29.

Ministry of Health and Population, Ramshah Path, Kathmandu, Nepal.

Background: Chronic kidney disease (CKD) leads to decreased quality of life (QOL) by increasing the risk of death during the progression of its pathogenesis. However, many factors can be improved to support QOL. This study aimed to assess QOL among CKD patients in Nepal and to determine the factors associated with their QOL. Read More

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http://dx.doi.org/10.1186/s12955-020-01458-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7325283PMC

Quantitative Assessment of Surgical Ergonomics in Otolaryngology.

Otolaryngol Head Neck Surg 2020 Jun 30:194599820932851. Epub 2020 Jun 30.

The Ohio State University College of Medicine, Columbus, Ohio, USA.

Objectives: Objective evaluation of the ergonomic risk of common otolaryngology procedures and assessment of work-related musculoskeletal pain and injury.

Study Design: Cross-sectional intraoperative assessment and survey.

Setting: Department of Otolaryngology at a tertiary children's hospital. Read More

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http://dx.doi.org/10.1177/0194599820932851DOI Listing

Are the Yellow and Red Marked Club-Tail the Same Species?

Insects 2020 Jun 24;11(6). Epub 2020 Jun 24.

Yunnan Key Laboratory of International Rivers and Transboundary Eco-security, Yunnan University, Kunming 650500, China.

(Fabricius, 1793) is currently comprised of ten subspecies, which were originally described under two names, and before 1909, when they were combined as one species. The main difference between them is the colour of abdomen and hindwing subterminal spots-yellow in and red in . Wing morphology, male and female genitalia, and molecular evidence (DNA barcodes) were analysed for multiple subspecies of and three other species-, , and . Read More

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http://dx.doi.org/10.3390/insects11060392DOI Listing

Microwave-Assisted Improved Extraction and Purification of Anticancer Nimbolide from (Neem) Leaves.

Molecules 2020 Jun 24;25(12). Epub 2020 Jun 24.

Department of Chemistry, Faculty of Science, Maejo University, Chiang Mai 50290, Thailand.

Nimbolide, a limonoid present in leaves of the neem tree (), is an anticancer compound against a panel of human cancer cell lines. The rapid process of extraction and purification of the nimbolide from the leaves of neem tree through microwave-assisted extraction (MAE) coupled with a chromatographic technique was accomplished. The crude with a maximum content of nimbolide could be recovered from neem leaves through MAE. Read More

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http://dx.doi.org/10.3390/molecules25122913DOI Listing

Prognostic Factors for All-Cause Mortality in Thai Patients with Fragility Fracture of Hip: Comorbidities and Laboratory Evaluations.

Medicina (Kaunas) 2020 Jun 24;56(6). Epub 2020 Jun 24.

Department of Orthopaedics, Faculty of Medicine, Chiang Mai University, Chiang Mai 50200, Thailand.

: Although the types of comorbidities and laboratory evaluations are major factors associated with mortality after hip fractures, there have been no studies of the association of these factors and mortality in Thai hip-fracture patients. This study aimed to identify prognostic factors associated with mortality after a hip fracture in the Thai population, including types of comorbidities, treatment-related factors, and laboratory evaluations. : This five-year retrospective study was conducted in a tertiary care hospital in Thailand. Read More

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http://dx.doi.org/10.3390/medicina56060311DOI Listing

EEG autoregressive modeling analysis: A diagnostic tool for patients with epilepsy without epileptiform discharges.

Clin Neurophysiol 2020 Jun 8;131(8):1902-1908. Epub 2020 Jun 8.

Department of Pediatrics, School of Medicine, College of Medicine, Kaohsiung Medical University, Taiwan, ROC; Departments of Pediatrics, Kaohsiung Medical University Hospital, Kaohsiung Medical University, Taiwan, ROC. Electronic address:

Objective: Numerous types of nonepileptic paroxysmal events, such as syncopes and psychogenic nonepileptic seizures, may imitate epileptic seizures and lead to diagnostic difficulty. Such misdiagnoses may lead to inappropriate treatment in patients that can considerably affect their lives. Electroencephalogram (EEG) is a commonly used tool in assisting diagnosis of epilepsy. Read More

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http://dx.doi.org/10.1016/j.clinph.2020.04.172DOI Listing

Oral fibrolipoma - Case report.

J Dent Sci 2020 Jun 4;15(2):227-229. Epub 2020 Apr 4.

Department of Dentistry, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

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http://dx.doi.org/10.1016/j.jds.2020.03.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305456PMC

Management of patients taking antithrombotic drugs before dental surgery.

J Dent Sci 2020 Jun 17;15(2):222-224. Epub 2020 Apr 17.

Department of Dentistry, Far Eastern Memorial Hospital, New Taipei City, Taiwan.

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http://dx.doi.org/10.1016/j.jds.2020.03.012DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305421PMC

Anemia, hematinic deficiencies, and gastric parietal cell antibody positivity in burning mouth syndrome patients with or without hyperhomocysteinemia.

J Dent Sci 2020 Jun 15;15(2):214-221. Epub 2020 May 15.

Graduate Institute of Clinical Dentistry, School of Dentistry, National Taiwan University, Taipei, Taiwan.

Background/purpose: Our previous study found that 170 of 884 burning mouth syndrome (BMS) patients have hyperhomocysteinemia. This study assessed whether these 170 BMS patients with hyperhomocysteinemia had significantly higher frequencies of anemia, hematinic deficiencies, and serum gastric parietal cell antibody (GPCA) positivity than 714 BMS patients without hyperhomocysteinemia or 442 healthy control subjects.

Materials And Methods: The blood hemoglobin (Hb) and serum iron, vitamin B12, folic acid, homocysteine, and GPCA levels in 170 BMS patients with hyperhomocysteinemia, 714 BMS patients without hyperhomocysteinemia, and 442 healthy control subjects were measured and compared. Read More

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http://dx.doi.org/10.1016/j.jds.2020.04.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305457PMC

Current practice patterns and training project of oral pathology specialists in Taiwan.

J Dent Sci 2020 Jun 28;15(2):168-175. Epub 2020 Mar 28.

School of Life Science, National Taiwan Normal University, Taipei, Taiwan.

Background/purpose: There were 70 oral pathology specialists (OPSs) in Taiwan till 2018. This study reported the current practice patterns and training project of OPSs in Taiwan.

Materials And Methods: This study exploited the secondary data analysis and interview to survey the current practice patterns and training project of OPSs in Taiwan. Read More

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http://dx.doi.org/10.1016/j.jds.2020.03.002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7305439PMC

A Department Wellness Initiative for Coping With Climate Distress in 2030.

J Grad Med Educ 2020 Jun;12(3):365-366

Professor, Residency Program Director, University of Washington.

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http://dx.doi.org/10.4300/JGME-D-19-00816.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301941PMC

Adlay Seed ( L.) Extracts Exhibit a Prophylactic Effect on Diet-Induced Metabolic Dysfunction and Nonalcoholic Fatty Liver Disease in Mice.

Evid Based Complement Alternat Med 2020 29;2020:9519625. Epub 2020 May 29.

Department of Biotechnology and Laboratory Science in Medicine, National Yang-Ming University, Taipei 11221, Taiwan.

Nonalcoholic fatty liver disease (NAFLD) is common worldwide and closely associated with metabolic dysfunction. NAFLD leads to a higher risk of development of severe liver diseases, such as nonalcoholic steatohepatitis (NASH), liver cirrhosis, and hepatocellular carcinoma (HCC). To date, no pharmacotherapy targeting NAFLD has received general approval. Read More

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http://dx.doi.org/10.1155/2020/9519625DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7275964PMC

Pheochromocytoma and gastrointestinal stromal tumours in an adult neurofibromatosis type 1 patient: a rare co-occurrence.

BMJ Case Rep 2020 Jun 28;13(6). Epub 2020 Jun 28.

Endocrine and Metabolism Unit, Internal Medicine Department, Faculty of Medicine, Chiang Mai University, Muang Chiang Mai, Chiang Mai, Thailand

The risk of tumours including pheochromocytoma and gastrointestinal stromal tumour (GIST) has been reported to be higher in neurofibromatosis type 1 (NF1) patients. The concomitant occurrence of these two tumours was rare in NF1 patient and most were symptomatic. In this case report, we describe the case of a 47-year-old man with NF1 who presented with microscopic haematuria. Read More

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http://dx.doi.org/10.1136/bcr-2020-235129DOI Listing

Novel mutation in gene causing autosomal recessive progressive rod-cone dystrophy.

Ophthalmic Genet 2020 Jun 29:1-4. Epub 2020 Jun 29.

UCLA Stein Eye Institute, Division of Retinal Disorders and Ophthalmic Genetics, Department of Ophthalmology, David Geffen School of Medicine, UCLA , Los Angeles, CA, USA.

Background: Recent advances in genetic sequencing techniques have improved the overall diagnostic yield for finding genetic causes for inherited retinal dystrophies (IRD). Rod-cone dystrophy is the most common IRD and is characterized by the primary involvement of the rod photoreceptors. Over 80 causal genes have been identified so far giving clinicians insight into the pathogenesis. Read More

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http://dx.doi.org/10.1080/13816810.2020.1783691DOI Listing

The in vitro effects of aflatoxin B on physiological functions of swine alveolar macrophages.

Vet Med Sci 2020 Jun 28. Epub 2020 Jun 28.

Department of Veterinary Medicine, College of Veterinary Medicine, National Chiayi University, Chiayi, Taiwan.

The toxic effects of aflatoxin B (AFB ) on the physiological functions of swine alveolar macrophages (SAM) were investigated. Freshly isolated SAM were incubated with various AFB concentrations (1.6 × 10  - 1. Read More

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http://dx.doi.org/10.1002/vms3.313DOI Listing

Drug Delivery System Targeting CD4 T Cells for HIV-1 Latency Reactivation Towards the Viral Eradication.

J Pharm Sci 2020 Jun 25. Epub 2020 Jun 25.

Division of Biochemistry and Biochemical Technology, Department of Chemistry, Faculty of Science, Chiang Mai University; Center of Excellence in Materials Science and Technology, Chiang Mai University 239 Huay Kaew Road, Chiang Mai 50200, Thailand. Electronic address:

Development of a cure for HIV/AIDS has been a great challenge due to the establishment of the HIV-1 viral reservoir, mainly within resting CD4 memory T cells. As a step towards a cure for HIV, this study aimed to develop an approach that reactivates HIV-1 latently infected cells by employing a drug delivery system using immunoliposomes targeting CD4 T cells. The immunoliposomes were examined for physicochemical properties and determined for their potential stability. Read More

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http://dx.doi.org/10.1016/j.xphs.2020.06.019DOI Listing

Gray matter volumetric correlates of behavioral activation and inhibition system traits in children: An exploratory voxel-based morphometry study of the ABCD project data.

Neuroimage 2020 Jun 24;220:117085. Epub 2020 Jun 24.

Department of Psychiatry, Yale University School of Medicine, New Haven, CT, 06520, USA; Department of Neuroscience, Yale University School of Medicine, New Haven, CT, 06520, USA; Interdepartmental Neuroscience Program, Yale University School of Medicine, New Haven, CT, 06520, USA. Electronic address:

Approach and avoidance represent two fundamental behavioral traits that develop early in life. Previous studies have examined the neural correlates of approach and avoidance traits in adults and adolescents. Here, using the data set of the Adolescent Brain Cognition Development project, we investigated the structural cerebral bases of behavioral activation system (BAS) and behavioral inhibition system (BIS) in children. Read More

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http://dx.doi.org/10.1016/j.neuroimage.2020.117085DOI Listing