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AJR Am J Roentgenol 2022 Jul 9;219(1):160-161. Epub 2022 Feb 9.

Department of Radiology, University of Pittsburgh School of Medicine and Magee-Womens Hospital of UPMC, 300 Halket St, Pittsburgh, PA 15213.

Proc (Bayl Univ Med Cent) 2022 23;35(1):76-77. Epub 2021 Aug 23.

Department of Dermatology, Texas Tech Health Sciences Center, Lubbock, Texas.

Basal cell carcinomas have been reported to arise within several different tumors. Without careful attention to detail, basal cell carcinomas may go unnoticed when presenting within or directly adjacent to another distinct tumor. The increased use and accessibility of dermoscopy has allowed dermatologists to detect skin cancers that might otherwise be undetected by the naked eye. Read More

J Cosmet Dermatol 2021 Dec 17. Epub 2021 Dec 17.

TOOsonix A/S, Hoersholm, Denmark.

Background: Existing therapeutic methods for reduction or removal of superficial vascular malformations and tumors have high risks of scarring and other complications that result in aesthetic appearance less favorable than the baseline. Patients are often cautioned against intervention, which can lead to psychosocial problems and low self-esteem. Improved treatment modalities are therefore relevant from both medical and aesthetic perspectives. Read More

Dermatology 2022 22;238(1):18-26. Epub 2021 Jul 22.

The University of Queensland Diamantina Institute, The University of Queensland, Dermatology Research Centre, Brisbane, Queensland, Australia.

Background: Cherry angiomas are common benign vascular skin lesions of unknown aetiology, found largely on the trunk. However, their exact anatomic distribution besides their truncal predisposition, and how they manifest in the general population, has not been characterised.

Methods: Three-dimensional (3D) total body imaging was obtained from 163 adult participants of a general population cohort study in Brisbane, Australia. Read More

J Cutan Pathol 2021 Nov 10;48(11):1335-1341. Epub 2021 Jun 10.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

Background: Gap junctions consisting of connexins (Cx) are fundamental in controlling cell proliferation, differentiation, and cell death. Cx43 is the most broadly expressed Cx in humans and is attributed an important role in skin tumor development. Its role in cutaneous vascular neoplasms is yet unknown. Read More

Oper Neurosurg (Hagerstown) 2021 06;21(1):E34-E35

Department of Neurosurgery, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA.

Pineal region tumors remain challenging lesions to safely resect because of their central location.1 Patients frequently present with symptoms associated with hydrocephalus and brainstem compression.2 Local anatomy, primarily the tentorium angle and venous anatomy, plays a central role in the selection of the approach. Read More

Clin Exp Dermatol 2021 Jul 12;46(5):946-948. Epub 2021 May 12.

Unit of Dermatology and Departments of Oncology, IRCCS San Raffaele Hospital, Milan, Italy.

Sao Paulo Med J 2021 Mar-Apr;139(2):186-189

MD, PhD. Otolaryngologist, Kolan International Hospital, Istanbul, Turkey.

Context: Various skin manifestations have been reported in coronavirus disease. It may be difficult to determine the etiology of these lesions in view of the increased frequency of handwashing during the pandemic, along with occurrences of irritant contact dermatitis and allergic contact dermatitis due to disinfectant use; usage of herbal medicine and supplements to strengthen the immune system; and urticarial or maculopapular drug eruptions due to COVID-19 treatment. The variety of associated skin manifestations seen with COVID-19 makes it challenging to identify virus-specific skin manifestations. Read More

J Cutan Pathol 2021 May 7;48(5):701-705. Epub 2021 Mar 7.

Department of Pathology, St. Vincent Evansville Medical Center, Evansville, Indiana, USA.

Castleman disease (CD) is an unusual lymphoproliferative disorder characterized by multiple lymphadenopathy accompanied by marked systemic inflammatory symptoms. CD can be unicentric (UCD) or multicentric (MCD), and it can be classified into three types based on histopathology: hyaline vascular type, plasma cell type, and mixed hyaline vascular and plasma cell type. CD involving skin is an unusual clinical manifestation. Read More

Dermatology 2021 30;237(6):981-987. Epub 2020 Nov 30.

Section of Dermatology and Infectious Diseases, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Background: Some risk factors for malignant melanoma (MM) are recognized.

Objective: To compare the strength of association between MM and eruptive cherry angiomas (CAs) with that of other well-known associations.

Methods: This cross-sectional study included all subjects referred to the Outpatient Dermatology-Oncology and Dermoscopy Units of the Universities of Ferrara and Bologna, Italy, over a 5-month period and submitted to total body skin examination. Read More

Dermatol Surg 2020 12;46(12):1691-1697

Department of Dermatology, University of California, Irvine, Irvine, California.

Background: Cherry angiomas are benign vascular proliferations of endothelial cells associated with aging. Currently, no mainstay of treatment for these vascular anomalies exists.

Objective: To review existing evidence-based therapies for the treatment of cherry angiomas. Read More

J Family Community Med 2020 May-Aug;27(2):109-113. Epub 2020 Jun 3.

Department of Medicine, Division of Dermatology, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Background: Cherry angiomas (CAs) are very common asymptomatic vascular skin lesions. There are only a few studies on CAs in the literature and those assessing risk factors of CAs are scarce. The aim of our study was to determine risk factors for the development of CAs. Read More

Dermatol Ther 2020 07 7;33(4):e13760. Epub 2020 Jul 7.

Department of Pathology, Hacettepe University, School of Medicine, Ankara, Turkey.

Dermatol Ther 2020 07 25;33(4):e13558. Epub 2020 May 25.

Division of Plastic Surgery, Doctoral Student on Medicine and Sciences of Health in the Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.

Transcutaneous use of dual diode lasers is a new option in dermatology. The aim of the study was to demonstrate the transcutaneous application of a dual laser in dermatologic outpatients. We used a laser system that combines 980 nm and 1470 nm wavelengths for treatment of vascular lesions. Read More

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):199-202

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Am J Surg Pathol 2020 02;44(2):255-262

Graduate Institute of Pathology, National Taiwan University College of Medicine, Taipei, Taiwan.

In this study, we aimed to present the clinicopathologic and molecular features of a distinct group of hemangioma with GNA mutations that exhibited prominent thrombosis and organization changes with florid intravascular endothelial cell proliferation that we provisionally termed "thrombotic hemangioma with organizing/anastomosing features." Twenty-six cases were included. No sex predilection was seen (male:female=13:13). Read More

J Eur Acad Dermatol Venereol 2019 Dec 19;33(12):e464-e465. Epub 2019 Jul 19.

Department of Dermatology, National Reference Center for Rare Skin Diseases, Bordeaux University Hospitals, Bordeaux, France.

Mod Pathol 2019 11 12;32(11):1657-1665. Epub 2019 Jun 12.

Graduate Institute of Pathology, National Taiwan University College of Medicine, Taipei, Taiwan.

Cherry hemangioma is the most common hemangioma in adult life. Neoplastic and non-neoplastic theories had both been proposed for its pathogenesis, but its nature is still poorly understood. We noted a significant subset of anastomosing hemangiomas and congenital hemangiomas harbored a population of small capillaries surrounded by a perivascular hyaline layer, reminiscent of the vessels seen in cherry hemangioma. Read More

JAMA Dermatol 2019 02;155(2):148-149

Division of Pediatric Dermatology, Medical College of Wisconsin, Milwaukee.

JAMA Dermatol 2019 02;155(2):211-215

Department of Dermatology, Massachusetts General Hospital, Boston.

Importance: Shared gene variants in benign-malignant process pairs, such as BRAF mutations common to benign nevi and melanoma, are associated with differing phenotypic manifestations. Study of gene mechanisms underlying cherry angioma may uncover previously unknown disease relationships.

Objective: To identify somatic mutations present in cherry angioma specimens by using targeted next-generation sequencing. Read More

Melanoma Res 2019 06;29(3):313-317

Section of Dermatology and Infectious Diseases, Department of Medical Sciences.

The aim of the study was to assess the association between eruptive cherry angiomas (CAs) and malignant melanoma (MM). Secondary objectives included investigating (i) this association in different age subgroups, and (ii) the association of eruptive CAs with other variables such as malignant tumours, in general, and immunosuppressive treatments. This cross-sectional study involved all patients referred to the outpatient Dermatology-Oncology Units of the universities of Ferrara and Bologna, Italy, and submitted to total body skin examination. Read More

Dermatology 2019 31;235(1):65-70. Epub 2018 Oct 31.

Department of Medicine, Surgery and Dentistry, Plastic Surgery Unit, University of Salerno, Plastic Surgery Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital Salerno, Salerno, Italy.

Background/aims: Cherry angiomas (CAs) are one of the most common vascular manifestations of the skin. By and large, these benign lesions often only represent an aesthetic problem. In the literature, few authors have focused on the pathogenesis of these lesions, and some risk factors have been identified, such as the presence of cutaneous and non-skin neoplasias. Read More

J R Coll Physicians Edinb 2018 Sep;48(3):210-216

Department of Dermatology, Mayo Medical School, Minnesota, USA.

Background: During dermatoscope-guided surgical procedures, we noticed that vasculature was easily identified. This study investigated the use of dermatoscopy in detecting and diagnosing vascular skin lesions.

Methods: We retrieved records of patients with vascular skin lesions who underwent dermatoscopy over a 3 month period, in two outpatient clinics affiliated with a university teaching hospital. Read More

Med Sci Monit 2018 Jul 20;24:5050-5053. Epub 2018 Jul 20.

Department of Dermatology, Faculty of Medicine, University of Çukurova, Adana, Turkey.

BACKGROUND I meticulously inspected trunks of 488 patients aged 40 years or older who had at least 1 truncal cherry angioma. MATERIAL AND METHODS The median number of truncal cherry angiomas was 4. Their median size was 3 millimeters. Read More

Am J Dermatopathol 2018 Dec;40(12):894-898

Department of Anatomic Pathology, Universitary Hospital of La Princesa, Madrid, Spain.

Campbell de Morgan spots (also known as adult hemangiomas, cherry angiomas, or senile angiomas) show clinical and histopathological features that make them distinct. Despite this, they are not included as benign vascular tumors in the current classification by the International Society for Vascular Anomalies (ISSVA). In the current study, we investigated the proliferation rate (Ki67) of the endothelia of 23 cases of Campbell de Morgan spots, as well as the immunoexpression of Wilms tumor protein 1 (WT1) by these vascular anomalies. Read More

J Eur Acad Dermatol Venereol 2018 Sep 30;32(9):e361-e363. Epub 2018 Mar 30.

Department of Dermatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):424-430

Department of Skin and Venereal Diseases, Government Medical College, Patiala, Punjab, India.

Eruptive pseudoangiomatosis is a rare viral exanthem characterized by acute onset of hemangiomata-like lesions, however, histological findings are distinct from that of true angiomas. This entity has been reported from Europe, North America, Japan, and Korea till date. Here, we report 12 cases of eruptive pseudoangiomatosis from a tertiary care hospital in Punjab. Read More

Semin Cutan Med Surg 2017 Dec;36(4):207-212

Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California, USA.

Notable milestones in the treatment of vascular lesions have been achieved over the past century. Many cutaneous vascular lesions can be successfully treated with lightbased devices. In this review, we will discuss the treatment of port-wine birthmarks, lymphatic malformations, infantile hemangiomas, rosacea, venous lakes, pyogenic granulomas, cherry angiomas, and angiofibromas using lasers, total reflection amplification of spontaneous emission of radiation, intense pulsed light, and photodynamic therapy. Read More

Acta Oncol 2018 05 30;57(5):709-711. Epub 2017 Nov 30.

d Department of Dermatology , Hospital Universitario Infanta Cristina , Parla , Madrid , Spain.