Search Our Scientific Publications & Authors

J Cutan Pathol 2021 May 21. Epub 2021 May 21.

Department of Dermatology, Venereology and Allergology, University Hospital Würzburg, Würzburg, Germany.

Background: Gap junctions consisting of connexins (Cx) are fundamental in controlling cell proliferation, differentiation, and cell death. Cx43 is the most broadly expressed Cx in humans and is attributed an important role in skin tumor development. Its role in cutaneous vascular neoplasms is yet unknown. Read More

Sao Paulo Med J 2021 Mar-Apr;139(2):186-189

MD, PhD. Otolaryngologist, Kolan International Hospital, Istanbul, Turkey.

Context: Various skin manifestations have been reported in coronavirus disease. It may be difficult to determine the etiology of these lesions in view of the increased frequency of handwashing during the pandemic, along with occurrences of irritant contact dermatitis and allergic contact dermatitis due to disinfectant use; usage of herbal medicine and supplements to strengthen the immune system; and urticarial or maculopapular drug eruptions due to COVID-19 treatment. The variety of associated skin manifestations seen with COVID-19 makes it challenging to identify virus-specific skin manifestations. Read More

Dermatol Surg 2020 12;46(12):1691-1697

Department of Dermatology, University of California, Irvine, Irvine, California.

Background: Cherry angiomas are benign vascular proliferations of endothelial cells associated with aging. Currently, no mainstay of treatment for these vascular anomalies exists.

Objective: To review existing evidence-based therapies for the treatment of cherry angiomas. Read More

J Family Community Med 2020 May-Aug;27(2):109-113. Epub 2020 Jun 3.

Department of Medicine, Division of Dermatology, College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia.

Background: Cherry angiomas (CAs) are very common asymptomatic vascular skin lesions. There are only a few studies on CAs in the literature and those assessing risk factors of CAs are scarce. The aim of our study was to determine risk factors for the development of CAs. Read More

Dermatol Ther 2020 07 7;33(4):e13760. Epub 2020 Jul 7.

Department of Pathology, Hacettepe University, School of Medicine, Ankara, Turkey.

Dermatol Ther 2020 07 25;33(4):e13558. Epub 2020 May 25.

Division of Plastic Surgery, Doctoral Student on Medicine and Sciences of Health in the Pontifical Catholic University of Rio Grande do Sul, Porto Alegre, Brazil.

Transcutaneous use of dual diode lasers is a new option in dermatology. The aim of the study was to demonstrate the transcutaneous application of a dual laser in dermatologic outpatients. We used a laser system that combines 980 nm and 1470 nm wavelengths for treatment of vascular lesions. Read More

Indian J Dermatol Venereol Leprol 2020 Mar-Apr;86(2):199-202

Department of Dermatology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Am J Surg Pathol 2020 02;44(2):255-262

Graduate Institute of Pathology, National Taiwan University College of Medicine, Taipei, Taiwan.

In this study, we aimed to present the clinicopathologic and molecular features of a distinct group of hemangioma with GNA mutations that exhibited prominent thrombosis and organization changes with florid intravascular endothelial cell proliferation that we provisionally termed "thrombotic hemangioma with organizing/anastomosing features." Twenty-six cases were included. No sex predilection was seen (male:female=13:13). Read More

J Eur Acad Dermatol Venereol 2019 Dec 19;33(12):e464-e465. Epub 2019 Jul 19.

Department of Dermatology, National Reference Center for Rare Skin Diseases, Bordeaux University Hospitals, Bordeaux, France.

Mod Pathol 2019 11 12;32(11):1657-1665. Epub 2019 Jun 12.

Graduate Institute of Pathology, National Taiwan University College of Medicine, Taipei, Taiwan.

Cherry hemangioma is the most common hemangioma in adult life. Neoplastic and non-neoplastic theories had both been proposed for its pathogenesis, but its nature is still poorly understood. We noted a significant subset of anastomosing hemangiomas and congenital hemangiomas harbored a population of small capillaries surrounded by a perivascular hyaline layer, reminiscent of the vessels seen in cherry hemangioma. Read More

JAMA Dermatol 2019 02;155(2):148-149

Division of Pediatric Dermatology, Medical College of Wisconsin, Milwaukee.

JAMA Dermatol 2019 02;155(2):211-215

Department of Dermatology, Massachusetts General Hospital, Boston.

Importance: Shared gene variants in benign-malignant process pairs, such as BRAF mutations common to benign nevi and melanoma, are associated with differing phenotypic manifestations. Study of gene mechanisms underlying cherry angioma may uncover previously unknown disease relationships.

Objective: To identify somatic mutations present in cherry angioma specimens by using targeted next-generation sequencing. Read More

Melanoma Res 2019 06;29(3):313-317

Section of Dermatology and Infectious Diseases, Department of Medical Sciences.

The aim of the study was to assess the association between eruptive cherry angiomas (CAs) and malignant melanoma (MM). Secondary objectives included investigating (i) this association in different age subgroups, and (ii) the association of eruptive CAs with other variables such as malignant tumours, in general, and immunosuppressive treatments. This cross-sectional study involved all patients referred to the outpatient Dermatology-Oncology Units of the universities of Ferrara and Bologna, Italy, and submitted to total body skin examination. Read More

Dermatology 2019 31;235(1):65-70. Epub 2018 Oct 31.

Department of Medicine, Surgery and Dentistry, Plastic Surgery Unit, University of Salerno, Plastic Surgery Unit, San Giovanni di Dio e Ruggi d'Aragona University Hospital Salerno, Salerno, Italy.

Background/aims: Cherry angiomas (CAs) are one of the most common vascular manifestations of the skin. By and large, these benign lesions often only represent an aesthetic problem. In the literature, few authors have focused on the pathogenesis of these lesions, and some risk factors have been identified, such as the presence of cutaneous and non-skin neoplasias. Read More

J R Coll Physicians Edinb 2018 Sep;48(3):210-216

Department of Dermatology, Mayo Medical School, Minnesota, USA.

Background: During dermatoscope-guided surgical procedures, we noticed that vasculature was easily identified. This study investigated the use of dermatoscopy in detecting and diagnosing vascular skin lesions.

Methods: We retrieved records of patients with vascular skin lesions who underwent dermatoscopy over a 3 month period, in two outpatient clinics affiliated with a university teaching hospital. Read More

Med Sci Monit 2018 Jul 20;24:5050-5053. Epub 2018 Jul 20.

Department of Dermatology, Faculty of Medicine, University of Çukurova, Adana, Turkey.

BACKGROUND I meticulously inspected trunks of 488 patients aged 40 years or older who had at least 1 truncal cherry angioma. MATERIAL AND METHODS The median number of truncal cherry angiomas was 4. Their median size was 3 millimeters. Read More

Am J Dermatopathol 2018 Dec;40(12):894-898

Department of Anatomic Pathology, Universitary Hospital of La Princesa, Madrid, Spain.

Campbell de Morgan spots (also known as adult hemangiomas, cherry angiomas, or senile angiomas) show clinical and histopathological features that make them distinct. Despite this, they are not included as benign vascular tumors in the current classification by the International Society for Vascular Anomalies (ISSVA). In the current study, we investigated the proliferation rate (Ki67) of the endothelia of 23 cases of Campbell de Morgan spots, as well as the immunoexpression of Wilms tumor protein 1 (WT1) by these vascular anomalies. Read More

J Eur Acad Dermatol Venereol 2018 Sep 30;32(9):e361-e363. Epub 2018 Mar 30.

Department of Dermatology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Indian J Dermatol Venereol Leprol 2018 Jul-Aug;84(4):424-430

Department of Skin and Venereal Diseases, Government Medical College, Patiala, Punjab, India.

Eruptive pseudoangiomatosis is a rare viral exanthem characterized by acute onset of hemangiomata-like lesions, however, histological findings are distinct from that of true angiomas. This entity has been reported from Europe, North America, Japan, and Korea till date. Here, we report 12 cases of eruptive pseudoangiomatosis from a tertiary care hospital in Punjab. Read More

Semin Cutan Med Surg 2017 Dec;36(4):207-212

Beckman Laser Institute and Medical Clinic, University of California, Irvine, Irvine, California, USA.

Notable milestones in the treatment of vascular lesions have been achieved over the past century. Many cutaneous vascular lesions can be successfully treated with lightbased devices. In this review, we will discuss the treatment of port-wine birthmarks, lymphatic malformations, infantile hemangiomas, rosacea, venous lakes, pyogenic granulomas, cherry angiomas, and angiofibromas using lasers, total reflection amplification of spontaneous emission of radiation, intense pulsed light, and photodynamic therapy. Read More

Acta Oncol 2018 05 30;57(5):709-711. Epub 2017 Nov 30.

d Department of Dermatology , Hospital Universitario Infanta Cristina , Parla , Madrid , Spain.

Dermatol Surg 2017 Nov;43(11):1313-1320

*University of Texas McGovern Medical School at Houston, Houston, Texas; †Department of Dermatology, University of Texas McGovern Medical School at Houston, Houston, Texas.

Background: Sodium tetradecyl sulfate (STS) is Food and Drug Administration approved for treatment of varicose veins, but numerous other off-label applications have been reported.

Objective: To describe the clinical uses of STS, as well as efficacy and adverse effects.

Methods: Review of studies searchable on PubMed from 1938 to 2016 describing clinical uses of STS to determine efficacy and adverse effects associated with various applications. Read More

Skinmed 2016;14(5):331-333. Epub 2016 Oct 1.

Department of Dermatology and Cutaneous Biology, and the Jefferson Center for International Dermatology, Sidney Kimmel Medical College at Thomas Jefferson University, Philadelphia, PA;

Plast Reconstr Surg 2016 Aug;138(2):410-417

Sacramento and Davis, Calif.

Background: Current treatments for infantile hemangiomas have unpredictable outcomes. The authors' aim was to develop a nanoporphyrin-delivered, high-efficacy treatment for infantile hemangiomas using a mouse hemangioendothelioma model.

Methods: The authors injected mouse hemangioendothelioma cells intradermally to axillary regions of 5-week-old, female, nude mice (n = 19) to induce hemangioendothelioma growth. Read More

Can Respir J 2016 6;2016:5682904. Epub 2016 Mar 6.

Department of Pathology, Singapore General Hospital, Singapore.

J Drugs Dermatol 2016 Jun;15(6):713-4

Cherry hemangiomas are common vascular proliferative lesions that can be concerning from a cosmetic perspective. Laser therapy is often used to eradicate cherry hemangiomas, but some lesions require multiple treatments or do not resolve at all. The suboptimal response to laser treatment may be due to limitations in penetration depth by vascular lasers such as the pulsed dye laser. Read More

Int J Dermatol 2016 Nov;55(11):e598-e600

Department of Medical Sciences, Section of Dermatology and Infectious Diseases, University of Ferrara, Ferrara, Italy.

Arch Dermatol Res 2016 Jul 8;308(5):373-7. Epub 2016 Apr 8.

Section of Microbiology and Medical Genetics, Department of Medical Sciences, University of Ferrara, Ferrara, Italy.

Human herpesvirus 8 (HHV8) has been hypothesized to be a potential cofactor for the development of diverse cutaneous vascular proliferative lesions, including eruptive cherry angiomas. Recent reports evidenced the influence of killer cell immunoglobulin-like receptor (KIR) gene diversity in defining the susceptibility to symptomatic herpesvirus infections. In this study, skin samples from vascular lesions and healthy controls were characterized simultaneously for the presence of HHV8 and for the KIR genotype, focusing upon the presence of the KIR2DL2/DS2 and KIR2DL3 genes, which have been associated to herpesvirus susceptibility. Read More

MMW Fortschr Med 2014 Nov;156(19):65