Chem Rev 2017 Nov 10. Epub 2017 Nov 10.
Biomolecular Photonics, Department of Physics, University of Bielefeld , Universitätsstraße 25, 33615 Bielefeld, Germany.
Super-resolved structured illumination microscopy (SR-SIM) is among the most rapidly growing fluorescence microscopy techniques that can surpass the optical diffraction limit. The strength of SR-SIM is that it can be readily applied to samples prepared for conventional fluorescence microscopy, requiring no sophisticated sample preparation protocols. As an extension of wide-field fluorescence microscopy, it is inherently capable of multicolor imaging and optical sectioning and, with sufficiently fast implementations, permits live cell imaging. Read More