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Phytother Res 2022 May 18. Epub 2022 May 18.

School of Biomedical & Pharmaceutical Sciences, Guangdong University of Technology, Guangzhou, China.

Rheumatoid arthritis (RA) is a chronic systemic autoimmune disease with predominant synovitis that has no complete cure or preventive treatment. Citrus essential oils, used in natural fragrances, contain a variety of functional ingredients that are worthy of investigation for their potential as natural anti-inflammatory drug sources. In this study, essential oils were hydro distilled from the peels of four citrus species: Citrus sinensis (L. Read More

Sci Rep 2022 May 14;12(1):8001. Epub 2022 May 14.

Dr. M.A. Kazi Institute of Chemistry, University of Sindh, Jamshoro, Pakistan.

Cadmium is found in many underdeveloped countries' aquatic bodies. Therefore, contaminated water should be treated before consumption; henceforth, efficient and customized point-of-use filtration is foreseeable. Traditionally, carbon-based sorbents have been utilized for such treatments, but alternative sources are also being investigated. Read More

Polymers (Basel) 2022 Apr 29;14(9). Epub 2022 Apr 29.

Food Science and Technology Program, School of Agro-Industry, Mae Fah Luang University, Chiang Rai 57100, Thailand.

Cellulose is an abundant component of the plant biomass in agricultural waste valorization that may be exploited to mitigate the excessive use of synthetic non-biodegradable materials. This work aimed to investigate the cellulose utilized by alkaline extraction with a prior bleaching process from rice straw, corncob, Phulae pineapple leaves, and Phulae pineapple peels. The bleaching and alkaline extraction process was performed using 1. Read More

Nutrients 2022 Apr 28;14(9). Epub 2022 Apr 28.

Kansei Fukushi Research Institute, Tohoku Fukushi University, 6-149-1 Kunimigaoka, Aoba, Sendai 989-3201, Japan.

As life expectancy increases, age-associated diseases such as Alzheimer's disease (AD) become a major health problem. The onset of AD involves neurological dysfunction due to amyloid-β accumulation, tau hyperphosphorylation, oxidative stress, and neuroinflammation in the brain. In addition, lifestyle-related diseases-such as dyslipidemia, diabetes, obesity, and vascular dysfunction-increase the risk of developing dementia. Read More

Skinmed 2022 30;20(2):160. Epub 2022 Apr 30.

Laser & Skin Surgery Center of New York, New York, NY.

Food Chem X 2022 Mar 1;13:100236. Epub 2022 Feb 1.

Chemical and Food Engineering Department, Federal University of Santa Catarina, Florianópolis, SC, C.P. 476, 88040-900, Brazil.

Deep eutectic solvents (DES) are emergent solvents with high extractability of bioactive compounds. Therefore, anthocyanin rich-fractions were recovered from jaboticaba peels by combining aqueous solutions of DES and pressurized liquid extraction (PLE). The extraction occurred at 10 MPa, 12 min, with conditions optimized through response surface methodology: 47% DES concentration, 90 °C, and 5. Read More

RSC Adv 2021 Nov 17;11(59):37049-37062. Epub 2021 Nov 17.

Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University Alkhartoom square Alexandria 21521 Egypt +20 1005294669.

Colocynth has a long history of use in traditional medicine for treatment of various inflammatory diseases where it is commonly roasted before being applied for medical purposes to reduce its toxicity. This study aims at tracking the effect of heat processing on the metabolic profile of the peels, pulps and seeds of colocynth fruit using UPLC-QqQ-MS-based metabolomics. The analysis resulted in tentative identification of 72 compounds belonging to different chemical classes. Read More

J Food Biochem 2022 Mar 25:e14150. Epub 2022 Mar 25.

Department of Biochemistry, Federal University of Technology, Akure, Nigeria.

This study analyzed the effects of functional cereals processed and produced from yellow corn, soybean, acha, orange peels and moringa leaves' polyphenolic content, glycemic index, starch composition and their effects on α-amylase and α-glucosidase enzymes in vitro. Functional cereals were produced as ready-to-eat cereals at different proportion with variations in the amount of measured acha flour, soybean flour, and blends of orange peels and moringa leaves while maintaining a constant amount of yellow corn. The produced orange peels and moringa leaves blends inclusion to functional cereals had significantly increased phenolic constituents, showed inhibitory activity on α-amylase and α-glucosidase enzymes in-vitro and reduced glycemic index, starch content and starch to sugar ratios. Read More

J Am Acad Dermatol 2022 Apr 22. Epub 2022 Apr 22.

Cooper University Hospital and Cooper Medical School of Rowan University, 1 Cooper Plaza, Camden, NJ 08103.

The optimal treatment of acne scarring is challenging because it involves consideration of several factors, including the type and number of scars, Fitzpatrick skin type, and the amount of downtime permissible to the patient. The second article in this CME series discusses the procedural treatments available for acne scarring, including the use of chemical peels, fillers, radiofrequency microneedling, lasers and surgical procedures. The indications for each modality, evidence for its benefits, and the adverse effects are discussed. Read More

J Sci Food Agric 2022 Apr 24. Epub 2022 Apr 24.

Department of Food Engineering, Faculty of Agriculture, Cukurova University, 01330, Adana, Turkey.

Background: Citrus fruit peels are considered as process waste in fruit juice industry but they are a valuable raw material due to their volatile and bioactive components. Drying is one of the most usual methods to preserve this material. In this study, four drying processes (convective drying: CD, microwave drying: MD, conductive hydro drying: CHD, and freeze drying: FD) were applied to the peels of four kinds of citrus fruits (orange, bitter orange, grapefruit and lemon). Read More

J Sci Food Agric 2022 Apr 19. Epub 2022 Apr 19.

Department of Pharmacognosy, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.

Background: The different parts of pomegranate fruit are considered a powerful mixture of bioactive compounds yet the peels and pulps of the fruits are usually discarded and considered as industrial waste. In this work, ultra-performance liquid chromatography coupled with triple quadrupole mass spectrometry (UPLC-QqQ-MS) was utilized for metabolomics analysis of different parts (peel, pulp, seed and juice) of pomegranate fruit cultivars to verify possible variations among the fruits and their waste products as potential sources of functional constituents.

Results: Orthogonal projection to latent structure-discriminant analysis (OPLS-DA) coefficient-plot showed enrichment of phenolic compounds such as punicalagin and ellagic acid derivatives in pulp samples while seeds class was enriched in phlorizin, catechin and quercetin, juice class showed abundance of naringenin and pelargonidin-3-pentoside while peels were enriched in anthocyanins and flavonoids including cyanidin diglycoside, quercetin and luteolin glycosides. Read More

Anal Chem 2022 Apr 14;94(16):6410-6416. Epub 2022 Apr 14.

Molecular Science and Biomedicine Laboratory, State Key Laboratory for Chemo/Bio-Sensing and Chemometrics, College of Material Science and Engineering, College of Chemistry and Chemical Engineering, College of Biology, Hunan University, Changsha 410082, China.

Based on luminol-capped Pt-tipped Au bimetallic nanorods (NRs) (L-Au-Pt NRs) as the anode emitter and SnS quantum dots (QDs) hybrid Eu metal organic frameworks (MOFs) (SnS [email protected] MOFs) as the cathode emitter, a dual-signal electrochemiluminescence (ECL) platform was designed for the ultrasensitive and highly selective detection of kanamycin (KAN). Using a dual-signal output mode, the ratiometric ECL aptasensor largely eliminates false-positives or false-negatives by self-calibration in the KAN assay process. To stimulate the resonance energy transform (RET) system, the KAN aptamer and complementary DNA are introduced for conjugation between the donor and acceptor. Read More

Plants (Basel) 2022 Mar 30;11(7). Epub 2022 Mar 30.

Laboratory for Separation Processes and Product Design, Faculty of Chemistry and Chemical Engineering, University of Maribor, Smetanova ulica 17, 2000 Maribor, Slovenia.

This study is focused on different extractions (Cold Maceration (CM), Ultrasonic Extraction (UE), Soxhlet Extraction (SE) and Supercritical Fluid Extraction (SFE)) of bioactive compounds from pomegranate ( L.) fruit peels using methanol, ethanol, and acetone as solvents in conventional extractions and changing operating pressure (10, 15, 20, 25 MPa) in SFE, respectively. The extraction yields, total phenols (TP) and proanthocyanidins (PAC) contents, and antioxidant activity of different extracts are revealed. Read More

Toxicol Rep 2022 29;9:628-635. Epub 2022 Mar 29.

Food Toxicology and Contaminants Department, National Research Centre, Dokki, Cairo, Egypt.

Organophosphorus pesticides (OPPs) cause great risk to human health as they are used globally. Therefore, the purpose of this research was to determine the total phenolics, flavonoids, and antioxidant activity of agricultural waste, as well as to control the pesticide residues (diazinon, and parathion) at a laboratory scale level using dried-milled fruit wastes. The pesticide residues parathion and diazinon were used at concentrations of 0. Read More

BMC Plant Biol 2022 Apr 9;22(1):186. Epub 2022 Apr 9.

Qinghai Provincial Key Laboratory of Tibetan Medicine Research and CAS Key Laboratory of Tibetan Medicine Research, Northwest Institute of Plateau Biology, Xining, 810008, China.

Background: Nitraria sibirica Pall. is an economic plant with two kinds of fruit color, widely spreads in the Qinghai Tibet Plateau. The chemical analysis and pharmacological evaluation had been carried out for several tens of years, the mechanism behind the fruit color differentiation is still unclear. Read More

J Environ Manage 2022 Jul 6;313:114981. Epub 2022 Apr 6.

Key Laboratory of Green Prevention and Control of Tropical Diseases and Pests (College of Plant Protection, Hainan University), Ministry of Education, Haikou, Hainan, 570228, PR China; Engineering Center of Agricultural Microbial Preparation Research and Development of Hainan (Hainan University), Haikou, Hainan, 570228, PR China. Electronic address:

Converting agricultural waste into value-added biopesticides to replace chemical pesticides for plant protection is a good alternative for environmental sustainability and resource recycling. In this study, five tropical wastes (cassava peels, banana pseudostem, coconut shell, sugarcane bagasse, and pineapple peels) were screened as substrates for the rapid production of biopesticide Trichoderma Brev T069. Five single tests and a Box-Behnken design (BBD) with response surface methodology were used to optimize the culture conditions to improve the spore yield. Read More

Sci Rep 2022 Apr 7;12(1):5840. Epub 2022 Apr 7.

Department of Chemistry, Government College University, Faisalabad, 38000, Pakistan.

Herein, a biosorbent was prepared from cucumber peels modified with ZnO nanoparticles (CPZiONp-composite) for the biosorption of metribuzin. Characterization of the composite was accomplished using FTIR, SEM, EDX, surface area pore size analyzer and pH of point of zero charge (pH). Biosorption study was executed in batch concerning the impact of pH, composite dose, contact time, initial metribuzin concentration and temperature. Read More

J Nanobiotechnology 2022 Apr 7;20(1):182. Epub 2022 Apr 7.

Department of Industrial Biotechnology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Sadat City, 22857, Egypt.

Background: Citrus production and trading are seriously affected by fungal decays worldwide; the green mold infection by Penicillium digitatum could be the most disastrous. The substitutions of chemical and synthetic fungicides with effectual natural alternatives are global demands; plant extract from pomegranates peels (PPE), biosynthesized selenium nanoparticles with PPE (PPE/SeNPs) and chitosan nanoparticles (NCT) were suggested as efficacious fungicidal agents/nanocomposites to control P. digitatum strains. Read More

Int J Phytoremediation 2022 Apr 2:1-11. Epub 2022 Apr 2.

Faculty of Engineering, Chemical Engineering Department, Cairo University, Cairo, Egypt.

A low-cost nano-particle material was successfully prepared using waste . Batch adsorption experiments were carried out to investigate the effect of different operating conditions on the removal of brilliant green (BG) dye from an aqueous solution. SEM images of nano-particles (PPNP) declared roughness of the surfaces and TEM images indicated a spheroid shape with an average particle size of 37 nm. Read More

Can J Infect Dis Med Microbiol 2022 25;2022:9410024. Epub 2022 Mar 25.

Department of Biology, College of Science, University of Hail, P.O. Box 2440, Ha'il, Saudi Arabia.

The interest for green synthesis of metallic nanoparticles (NPs) has acquired particular attention due to its low toxicity and economic feasibility compared with chemical or physical process. Here we carried out an extracellular synthesis approach of silver nanoparticles (AgNPs) using dried orange peel extract. Characterization studies revealed the synthesis of 25-30 nm AgNPs with distinct morphology as observed in transmission electron microscopes. Read More

Clin Cosmet Investig Dermatol 2022 14;15:455-469. Epub 2022 Mar 14.

Salar Hazany M.D. Inc, Beverly Hills, CA, USA.

Scarring is a dire consequence of acne vulgaris. Particularly, atrophic acne scarring is highly prevalent among young adults, and its physical and psychological effects can persist throughout their lives if left untreated. This literature review will analyze various non-energy-based approaches to treating atrophic acne scarring, emphasizing recent advances within the last 5 to 10 years. Read More

Carbohydr Polym 2022 Jun 2;286:119298. Epub 2022 Mar 2.

Biomass & Bioenergy Research Center, College of Plant Science & Technology, Huazhong Agricultural University, Wuhan 430070, China; Laboratory of Biomass Engineering & Nanomaterial Application in Automobiles, College of Food Science & Chemical Engineering, Hubei University of Arts & Science, Xiangyang, China. Electronic address:

Pectin is a minor wall polysaccharide with potential applications for bioproducts. Despite the application of specific plants and biomass-based sorbents for environmental remediation, little has been reported about characteristic roles of pectin. Using the natural rice mutant (Osfc16) treated with Cd, this study explored that pectin could predominately enhance Cd accumulation with lignocellulose, mainly due to remarkably raised uronic acids deposition. Read More

Molecules 2022 Mar 9;27(6). Epub 2022 Mar 9.

LEPABE-Laboratory for Process Engineering, Environment, Biotechnology and Energy, Faculty of Engineering, University of Porto, Rua Dr. Roberto Frias, 4200-465 Porto, Portugal.

The avocado peel is an agro-industrial by-product that has exhibited a massive increase in its production in the last few years. The reuse and valorisation of this by-product are essential since its disposal raises environmental concerns. In the present study, ethanolic extracts of avocado peels of the Hass variety were obtained, for three extraction times (1. Read More

Foods 2022 Mar 9;11(6). Epub 2022 Mar 9.

Engineering Graduate Program, Federal University of Pampa, 1650, Maria Anunciação Gomes de Godoy Avenue, Bagé 96413-172, Brazil.

This research focused on the development of active and intelligent films based on a carrageenan biopolymer incorporated with jaboticaba peels extract (JPE). The bioactive extract was obtained by maceration extraction and showed high concentrations of total phenolic content (TP), total anthocyanin (TA), cyanidin-3-glucoside (Cn-3-Glu), antioxidant activity (AA), and microbial inhibition (MI) against , being promising for use as a natural additive in food packaging. The carrageenan films were produced using the casting technique, incorporating different concentrations of JPE, and characterized. Read More

Rocz Panstw Zakl Hig 2022 ;73(1):79-86

Laboratory of Biotechnology, Biochemistry, and Nutrition, Training and Research Unit on Nutrition and Food Sciences, Department of Biology, Faculty of Sciences, Chouaib Doukkali University, El Jadida 24 000, Morocco.

Background: In Morocco, fava beans are widely used as a main meal or as an ingredient in various traditional recipes, in the form of fresh ripe seeds or dry seeds. In the past, the tender skin of bean pods was also used in certain specific dishes, thus diversifying the diet. However, the peels of the tender bean pods are currently less or not used and considered waste. Read More

J Clin Aesthet Dermatol 2022 Jan;15(1):48-52

All authors are with Mahatma Gandhi Medical College and Research Institute in Pondicherry, Pondicherry India.

Background: Acne is one of the most commonly faced dermatological complaints in our day-to-day practice. Among the various treatment modalities for acne and postacne pigmentation, chemical peeling is a promising and emerging treatment modality. Although various peeling agents are available, there is a lack of research comparing their efficacy. Read More

Food Chem 2022 Aug 1;385:132604. Epub 2022 Mar 1.

Department of Food Science and Technology, Ionian University, Argostoli 28100, Kefalonia, Greece. Electronic address:

Edible films were developed using whey protein concentrate (WPC) and a natural bio-polymer, namely bacterial cellulose (BC). BC was produced via fermentation from orange peels and subsequently acid-hydrolyzed to obtain BC nanowhiskers (BCNW) with high crystallinity (XRD analysis). Morphology of BCNW was analyzed by SEM, TEM, and AFM. Read More

J Cosmet Dermatol 2022 Mar 15. Epub 2022 Mar 15.

Department of Dermatology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.

Post-inflammatory hyperpigmentation (PIH) is a common cosmetic complaint affecting patient quality of life. PIH has been proven to disproportionately affect skin of color. While several treatment options exist, special consideration must be given when managing PIH in patients of color, as topical treatments and aesthetic procedures, such as chemical peels and lasers, may either exacerbate or prove ineffective against PIH. Read More

Crit Rev Food Sci Nutr 2022 Mar 14:1-16. Epub 2022 Mar 14.

Centro Tecnológico de la Carne de Galicia, Ourense, Spain.

Food processing, especially the juice industry, is an important sector that generate million tons of residues every. Due to the increasing concern about waste generation and the interest in its valorization, the reutilization of by-products generated from the processing of popular fruits of the genus (rich in high-added value compounds) has gained the spotlight in the food area. This review aims to provide an overview of the high added-value compounds found in the residues of fruits (peach, nectarine, donut peach, plum, cherry, and apricot) processing and applications in the food science area. Read More

Front Nutr 2022 23;9:825381. Epub 2022 Feb 23.

State Key Laboratory of Tea Plant Biology and Utilization, International Joint Laboratory on Tea Chemistry and Health Effects of Ministry of Education, Anhui Agricultural University, Hefei, China.

The peel of "Chachi" (CP) possesses various health-promoting benefits and is not only one of the most famous Chinese herbal medicine, but also an ingredient in fermented foods. In the present study, the effects of storage years (1-, 3-, 4-, 5-, 6-, and 11-years) on the chemical profiling and potential bioactive compounds of CP were compared by metabolomics and bioactivity analysis. With the increase of storage time, the content of hesperidin significantly decreased, but nobiletin, 3,5,6,7,8,3',4'-heptamethoxyflavone, and tangeretin were increased. Read More