Search Our Scientific Publications & Authors

Environ Sci Pollut Res Int 2019 Feb 15. Epub 2019 Feb 15.

Department of Chemical Engineering, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand, 247 667, India.

This research work aims to develop a biomaterial entrapped with iron nanoparticles by green synthesis method in which biomass act as both reducing and capping agent. Iron nanoparticles embedded in Citrus limetta peels were characterised using ICP-MS for determination of metal loading, XRD, XPS for crystallinity and oxidation states, TEM followed by FESEM-EDS for particle size and morphology. Sizes of nanoparticles were found to be in the range of 4-70 nm. Read More

J Am Acad Dermatol 2019 Feb 1. Epub 2019 Feb 1.

Laboratory of Phytotherapy, Phytotherapy Technology and Chemistry of Natural Products, Department of Pharmaceutical Sciences, State University of Ponta Grossa, Brazil.

Lipids Health Dis 2019 Jan 31;18(1):35. Epub 2019 Jan 31.

Department of Food Science, Nutrition & Home Economics, Government College University, Faisalabad, Pakistan.

Background: Fish meat and its products are usually accepted as good source of biological high value food components and especially for polyunsaturated fatty acids. The quality of fish meat products is considered to be decreased by the lipid peroxidation which leads to reduction in nutritional quality, financial loss and severe health problems. Many tactics are present to reserve their quality and safety. Read More

J Cosmet Dermatol 2019 Jan 20. Epub 2019 Jan 20.

Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Lodz, Lodz, Poland.

Background: Topical applications of alpha-hydroxy acids and poly hydroxy acids in the form of peels gained popularity. To enhance the effect of these substances, aluminum oxide crystal microdermabrasion can be used in one procedure.

Aims: The assessment of skin hydration, elasticity, and TEWL after using lactobionic acid in the form of 20% peel and lactobionic acid in the form of 20% peel combined with aluminum oxide crystal microdermabrasion. Read More

Environ Sci Pollut Res Int 2019 Jan 15. Epub 2019 Jan 15.

CSIR-National Chemical Laboratory, Pune, 411008, India.

Fruit peels are a rich source of cellulose, hemicellulose, phenolic compounds, and terpenic compounds. Thus, they have the potential to be a novel renewable, sustainable, and low-cost raw material (source) for the production of several value-added products based on framework and concepts such as waste hierarchy that includes biofertilizers, dietary fiber, animal feed, industrial enzymes, substrate for the bioactive compounds production, synthesis of nanomaterials, and clean energy (from residual biomass). With a view of evaluating the environmental burden of biorefinery, a life cycle assessment (LCA) is performed for a representative citrus waste (CW) biorefinery. Read More

FASEB J 2019 Jan 14:fj201802005R. Epub 2019 Jan 14.

Division of Molecular and Cellular Biology, Department of Biochemistry and Molecular Biology, Kobe University Graduate School of Medicine, Kobe University, Kobe, Japan.

Cell competition is involved in mammalian embryogenesis and tumor elimination and progression. It was previously shown that, whereas NIH3T3 mouse fibroblasts expressing high levels of the yes-associated protein 1(YAP1) target TEA domain family (TEAD) transcription factors become "winners" in cell competitions, Madin-Darby canine kidney cells expressing activated YAP1 become "losers" and are eliminated from culture monolayers. Thus, YAP1's role in cell competitions is clearly context dependent. Read More

Nat Prod Res 2019 Jan 12:1-6. Epub 2019 Jan 12.

c Faculty of Pharmaceutical Sciences, University of Campinas (UNICAMP), Campinas, SP, Brazil AND Chemical, Biological and Agricultural Pluridisciplinary Research Center (CPQBA) , University of Campinas (UNICAMP) , Paulínia , SP , Brazil.

A flavonoid enriched extract (FE) was obtained from grape peels, and in vitro SPF, antioxidant activity, and effects on cell viability of this extract were tested with the intent to develop a cosmetic product. A formulation was developed with the FE, and the stability of this mixture was evaluated in terms of pH, density, viscosity, and SPF (90-days). FE showed no cytotoxicity to human keratinocytes and an in vitro SPF of 18. Read More

Food Chem 2019 May 6;279:356-363. Epub 2018 Dec 6.

Graduate School of Food and Nutritional Science, Toyo University, 1-1-1, Izumino, Itakura-machi, Ora-gun, Gunma 374-0193, Japan. Electronic address:

Bulky hard peel of Citrus natsudaidai is discarded and not utilized enough in Japan. In this study, the nutritional composition and volatile components of three cultivars of C. natsudaidai peel were determined. Read More

Int J Biol Macromol 2018 Dec 24;126:238-245. Epub 2018 Dec 24.

Laboratoire des Substances Naturelles, Institut National de Recherche et d'Analyse Physico-chimique (INRAP), Pôle Technologique de Sidi Thabet, 2020 Sidi Thabet, Tunisia. Electronic address:

Valorization of agricultural by-products constitutes a promising approach for sustainable development. Mucilage was extracted with a simple and safe method from Opuntia ficus-indica fruit peels which are considered as unexploited wastes resulting from the huge consumption of prickly pears. Structural and functional properties of the extracted polysaccharide were studied. Read More

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Chemical peeling, or chemexfoliation, has been used for centuries to improve signs of ultraviolet light-induced sun damage. Over the last 30 years, the science behind chemical peeling has evolved, increasing our understanding of the role of peeling ingredients and treatment indications. The depth of peels is directly related to improved results and to the number of complications that can occur. Read More

J Am Acad Dermatol 2018 Dec 11. Epub 2018 Dec 11.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Once considered the gold standard for deep facial resurfacing, the classical Baker-Gordon phenol-croton oil peel has largely been replaced by formulas with lower concentrations of phenol and croton oil. The improved safety profile of deep peels has ushered in a new era in chemical peeling. Wrinkles can be improved and skin tightened with more subtle and natural results. Read More

J Am Acad Dermatol 2018 Dec 5. Epub 2018 Dec 5.

Department of Dermatology, Emory University School of Medicine, Atlanta, GA.

Biotechnol Prog 2018 Dec 3. Epub 2018 Dec 3.

Process and Systems Engineering Centre (PROSYS), Dept. of Chemical and Biochemical Engineering, Technical University of Denmark, Søltofts Plads Building 229, DK-2800 Kgs., Lyngby, Denmark.

Different opportunities are explored to evaluate quality variation in raw materials from biological origin. Assessment of raw materials attributes is an important step in a bio-based production as fluctuations in quality are a major source of process disturbance. This can be due to a variety of biological, seasonal, and supply scarcity reasons. Read More

Environ Sci Pollut Res Int 2018 Nov 29. Epub 2018 Nov 29.

Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, 769008, India.

In this study, aqueous extracts of Musa paradisica (banana) peels and Dolichos lablab (Indian beans) seeds were prepared and tested as natural coagulants for turbidity removal from simulated turbid water. Effects of extraction time (15, 30, and 45 min), dosage (0.2 to 1. Read More

Phytomedicine 2018 Nov 17;50:231-237. Epub 2017 Aug 17.

Phytochemistry and Phytopharmacology Division, Jawaharlal Nehru Tropical Botanic Garden and Research Institute, Pacha-Palode 695 562 Thiruvananthapuram, Kerala, India. Electronic address:

Background: Citrus comprises the largest fruit sector worldwide, and its fruit peels are the dominant 'residue' of the industry. Though not profitable, Citrus peels are industrially used for making some byproducts (cattle feed, molasses, ethanol, fiber) and for the extraction of bioactives (flavonoids, essential oils, d-limonene). Still huge amounts of peels are wasted by Citrus industries, juice and other vending sectors. Read More

Plast Surg (Oakv) 2018 Nov 18;26(4):250-255. Epub 2018 Jan 18.

Department of Plastic Surgery, Assaf Harofeh Medical Center, Tzrifin, Israel.

Background: Phenol chemical peeling (PCP) treatment is associated with prolonged recovery and sustained adverse events. Hyperbaric oxygen therapy (HBOT) is known to accelerate wound healing. The purpose of the current study was to evaluate the effect of HBOT on PCP recovery period and adverse events. Read More

Carbohydr Polym 2019 Feb 26;205:427-436. Epub 2018 Oct 26.

Dept. Biotechology, Ghent University, Belgium.

The present work focuses on the development of novel injectable, self-gelling composite hydrogels based on two types of low esterified amidated pectins from citrus peels and apple pomace. Sol-gel-derived, calcium-rich bioactive glass (BG) fillers in a particle form are applied as delivery vehicles for the release of Ca ions to induce internal gelation of pectins. Composites were prepared by a relatively simple mixing technique, using 20% w/v BG particles of two different sizes (2. Read More

Nat Prod Res 2018 Nov 16:1-5. Epub 2018 Nov 16.

a Laboratoire des Interfaces et des Matériaux Avancés (LIMA), Faculté des Science de Monastir , Université de Monastir , Monastir , Tunisia.

In this study, Box-Behnken Design was used to optimize the ultrasonic extraction of polysaccharides from quince peels (QPPs) by ascorbic acid and the effect of extraction temperature, extraction time and pH was evaluated. Under optimized conditions of temperature 90 °C, 60 min sonication time and pH = 3.26, the extraction yield, the galacturonic acid yield and the concentration of sample required to scavenge 50% of 2,2'-azino-bis(3-ethylbenzothiazoline-6-sulphonic) acid (ABTS) values of QPPs were respectively 10. Read More

Heliyon 2018 Oct 2;4(10):e00885. Epub 2018 Nov 2.

Division of Crop Utilization, ICAR- Central Tuber Crops Research Institute, Thiruvananthapuram 695 017, Kerala, India.

The ethanol yields from lignocellulo-starch biomass (peels of sweet potato, elephant foot yam, tannia, greater yam and beet root) by fed-batch separate hydrolysis and fermentation (F-SHF) and simultaneous saccharification and fermentation (F-SSF) using were compared. Fed-batch saccharification of steam or dilute sulphuric acid pretreated biomass enhanced the reducing sugar yield which resulted in high RS consumption, volumetric ethanol productivity and ethanol yield during the first 24 h fermentation under F-SHF mode, while continuous production and utilization of reducing sugars occurred up to 72 h in F-SSF. Dilute sulphuric acid pretreated residues under F-SHF gave higher ethanol yield (34-43 g/L) and productivity (274-346 ml/kg dry biomass) than steam pretreatment (27-36 g/L and 223-295 ml/kg respectively), while F-SSF was superior for steam pretreated peels of sweet potato, elephant foot yam and tannia giving ethanol yields from 281 to 302 ml/kg. Read More

Food Chem 2019 Mar 9;276:475-484. Epub 2018 Oct 9.

Laboratório de Pesquisa, Desenvolvimento e Inovação em Bioprodutos, Universidade Federal de Goiás, Faculdade de Farmácia, Praça Universitária, 1166 - Setor Leste Universitário, CEP: 74605220 Goiânia, GO, Brazil.

Jaboticaba (Myrciaria cauliflora) is considered a "super fruit" due to its remarkable phenolic content and antioxidant capacity. Despite the great potential of its peels, to our knowledge the investigation of novel nanostructured systems with this natural raw material, still considered an industrial residue, is scarce. The present study aimed to obtain nanodispersions with its peel's extract through a low energy method. Read More

Chimia (Aarau) 2018 Oct;72(10):728-732

HES-SO Valais-Wallis (University of Applied Sciences and Arts Western Switzerland Valais), Institute of Life Technologies, Route du Rawyl 47, CH-1950 Sion 2;, Email:

Yuzu is a citrus fruit cultivated mainly in northeast Asia. Due to the huge gastronomic interest emerging in recent years, some attempts to grow yuzu in Europe are being made. Juice and peel of yuzu cultivated in Switzerland have been characterised in this study. Read More

Molecules 2018 Oct 16;23(10). Epub 2018 Oct 16.

College of Horticulture and Landscape Architecture, Southwest University, Chongqing 400716, China.

In this study, a preparative separation method was established to simultaneously isolate the polymethoxylated flavones (PMFs) from the peel of "Dahongpao" tangerine using macroporous adsorptive resins (MARs) combined with prep-HPLC. The total PMFs were enriched using MARs to remove most sugars, water-soluble pigments, and flavanones, and the eluents obtained were analyzed by ultra-performance liquid chromatography (UPLC) to determine the PMF composition. The separation and purification of PMFs were carried out by using a mass spectrometry-guided prep-HPLC with a gradient elution of acetonitrile-water (/), simultaneously. Read More

Food Sci Biotechnol 2018 Jun 27;27(3):623-629. Epub 2017 Dec 27.

4Cassava and Starch Technology Research Laboratory, National Center for Genetic Engineering and Biotechnology (BIOTEC), National Science and Technology Development Agency (NSTDA), Pathum Thani, 12120 Thailand.

Pectins were extracted from banana peels of five different varieties using citric acid solution. The chemical characteristics of banana peel pectins were investigated and compared with citrus peel and apple pomace pectins which were extracted under the same extraction conditions to assess the potential of banana peels as an alternative source of commercial pectin. The yield of banana peel pectins ranged from 15. Read More

Curr Med Chem 2018 Sep 26. Epub 2018 Sep 26.

Department of Pharmacy, University of Salerno, Fisciano (SA). Italy.

BioActive Compounds (BACs) recovered from food or food by-product matrices are useful in maintaining well being, enhancing human health, and modulating immune function to prevent or to treat chronic diseases. They are also generally seen by final consumers as safe, non-toxic and environment-friendly. Despite the complex process of production, chemical characterization, and assessment of healthy effects, BACs must also be manufactured in stable and bioactive ingredients to be used in pharmaceutical, food and nutraceutical industry. Read More

Dermatol Ther 2018 11 24;31(6):e12714. Epub 2018 Sep 24.

Chair of Cosmetology, Department of Cosmetology and Aesthetic Dermatology, Faculty of Pharmacy, Medical University of Łódź, Łódź, Poland.

Skin microneedling accelerates the process of skin regeneration through the creation of numerous microinjuries which emerge when skin is deeply punctured with very thin needles. The whole procedure evokes various reactions which can be divided into three major phases: inflammation, proliferation, and remodeling. It activates platelet growth factors which are responsible for the stimulation of fibroblasts to produce collagen and elastin. Read More

Waste Manag Res 2018 Sep 17:734242X18798699. Epub 2018 Sep 17.

Department of Chemical Engineering and Food Technology, Faculty of Sciences, IVAGRO, University of Cádiz, Spain.

Nowadays, significant amounts of agro-industrial wastes are discarded by industries; however, they represent interesting raw materials for the production of high-added value products. In this regard, orange peels (ORA) and exhausted sugar beet cossettes (ESBC) have turned out to be promising raw materials for hydrolytic enzymes production by solid state fermentation (SSF) and also a source of sugars which could be fermented to different high-added value products. The maximum activities of xylanase and exo-polygalacturonase (exo-PG) measured in the enzymatic extracts obtained after the SSF of ORA were 31,000 U·kg and 17,600 U·kg, respectively; while for ESBC the maximum values reached were 35,000 U·kg and 28,000 U·kg, respectively. Read More

J Clin Aesthet Dermatol 2018 Aug 1;11(8):21-28. Epub 2018 Aug 1.

Drs. Soleymani, Lanoue, and Rahman are with the Department of Dermatology at Stanford University School of Medicine in Redwood City, California.

Chemoexfoliation, also known as chemical peeling, is a method of targeted cutaneous ablation using specific caustic agents that allow for rapid, predictable, and uniform thickness of chemoablation to a desired cutaneous depth, ultimately resulting in an improved appearance of skin. In this review, we provide an up-to-date analysis of all currently available chemical peels for dermatologic use, as well as a step-by-step instructional protocol for an algorithmic approach to treatment. A comprehensive search of the Cochrane Library, MEDLINE, and PUBMED databases was performed to identify relevant literature investigating chemical peeling agents. Read More

Vet Sci 2018 Sep 12;5(3). Epub 2018 Sep 12.

Department of Veterinary Medicine, Federal University of Paraná, Curitiba, PR 80035-050, Brazil.

(L.) Mill. is a xerophylous plant that originated in tropical and subtropical America. Read More

J Cosmet Dermatol 2018 Oct 10;17(5):802-810. Epub 2018 Sep 10.

Department of Dermatology and Venereology, Faculty of Medicine, Zagazig University, Zagazig, Egypt.

Background: Successful management of acne involves choosing proper medication. Chemical peeling is a well-known option in treatment of acne vulgaris.

Objective: To evaluate and compare the clinical efficacy and safety of combination chemical peels vs single peel in treatment of mild-to-moderate acne. Read More

Food Chem 2019 Jan 17;270:53-60. Epub 2018 Jul 17.

DEMEC/Universidade Federal de Minas Gerais, Av. Antônio Carlos, 6627, 31270-901 Belo Horizonte, MG, Brazil.

Buriti by-products flours were evaluated as sources of dietary fibers and natural antioxidants. All flours presented chemical characteristics that allowed classification as high dietary fiber powders. Presence of pectic polysaccharides, arabinoxylans and xyloglucans was inferred by the neutral monosaccharides profile. Read More

J Cosmet Dermatol 2018 Aug 26. Epub 2018 Aug 26.

Department of Dermatology, Faculty of Medicine, Minia University, Al-Minya, Egypt.

Background: Melasma is an acquired disorder of symmetrical hyperpigmentation. Several treatment methods are available for patients with melasma, including topical compounds, broad-spectrum photoprotection, camouflage, chemical peels, and laser and light therapies which represent potentially promising options for patients who are refractory to other modalities.

Objective: To evaluate and compare the clinical, histopathological, and immunohistochemical changes in melasma after fractional Er:YAG laser versus fractional Er:YAG laser and topical steroids. Read More

Cutis 2018 Jul;102(1):21;25;47;48

Goldenberg Dermatology, PC, New York, USA.

Acne vulgaris and postacne scarring are common in the general population. Even after lesions have resolved, scarring can lead to detrimental psychologic effects and can negatively impact patients' quality of life. Fortunately, there have been several recent advances in therapeutic options to treat acne scarring. Read More

Trop Life Sci Res 2018 Jul 6;29(2):89-102. Epub 2018 Jul 6.

Department of Biology, College of Education for Pure Sciences, Diyala University, Diyala, Iraq.

Aqueous extracts prepared from the powdered entire pomaces and their parts (seeds and peels) of two Iraqi grape cultivars (Shada and Des-Alanez) were evaluated for their ovicidal, larvicidal, and pupicidal activities against housefly, (Linnaeus 1758) and compared them with chemical insecticide (Agita 10 WG; Austria). The highest insecticidal activity was shown by the aqueous extracts of powdered seeds followed by the entire pomace and then peels. The water extracts from the seeds, peels and pomaces were able to inhibit completely the hatching of the eggs at a concentration of 150 μg/ml while the Agita insecticide was able to inhibit the hatching process at a concentration of 50 μg/ml. Read More

Food Chem 2018 Dec 2;269:258-263. Epub 2018 Jul 2.

Department of Nutrition and Food Science, University of Granada, Campus of Cartuja, 18071 Granada, Spain; Institute of Nutrition and Food Technology 'José Mataix', Biomedical Research Centre, University of Granada, Avenida del Conocimiento s/n, E-18071 Granada, Spain. Electronic address:

Potato processing generates large amounts of by-products, which include potato peels and the outer layers of flesh, which contain phenolic compounds. The purpose of this study was to establish an extraction method for phenolic compounds from industrial potato by-products by using response surface methodology (RSM). Box-Behnken design (BBD) was performed to optimize the extraction conditions of phenolic compounds considering different extraction temperature, ratios of ethanol/water, time of extraction and sample/solvent ratio. Read More

Ultrason Sonochem 2018 Nov 27;48:453-462. Epub 2018 Jun 27.

Department of Chemical Engineering, Institute of Chemical Technology, Mumbai, India.. Electronic address:

In the present work, tomato peels were pre-treated using combination of ultrasound and enzyme co-immobilized amino-functionalized magnetic nanoparticles (AMNPs) for the efficient release of lycopene. To achieve maximum activity of enzymes in the co-immobilized form, optimization of several parameters were carried out. Moreover, the influence of ultrasound and enzyme co-immobilized magnetic nanoparticles on lycopene release was studied. Read More

J Nat Prod 2018 Aug 2;81(8):1877-1883. Epub 2018 Aug 2.

Division of Natural Drug Discovery, Department of Translational Research, Institute of Natural Medicine , University of Toyama , 2630 Sugitani , Toyama 930-0194 , Japan.

Human pancreatic cancer cells have an extreme tolerance to nutrition starvation, enabling them to survive in a hypovascular tumor microenvironment. Searching for agents that preferentially inhibit cancer cell viability under nutrition starvation conditions is a novel antiausterity strategy in anticancer drug discovery. In the present study, a hexane extract of the peels of Citrus hystrix fruits showed preferential cytotoxicity against PANC-1 human pancreatic cancer cells using a nutrient-deprived medium. Read More

Environ Sci Pollut Res Int 2018 Oct 31;25(28):27982-27991. Epub 2018 Jul 31.

Shandong Key Laboratory of Water Pollution Control and Resource Reuse, School of Environmental Science and Engineering, Shandong University, Jinan, 250100, People's Republic of China.

Herein, we fabricated a novel carbohydrate-based adsorbent by using the pomelo peel (PP) as the biocarrier. The virgin PP was embedded with hydrous zirconium oxide (HZO) nanoparticle, forming the HZO-PP composites for highly efficient fluoride adsorption. Characteristics of HZO-PP were determined by TEM, SEM, XPS, XRD, BET surface area, and FTIR. Read More

Clin Cosmet Investig Dermatol 2018 16;11:365-372. Epub 2018 Jul 16.

Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, FL, USA,

Acne vulgaris is the most common skin disorder in adolescents and young adults. It carries a significant psychological and economic burden to patients and society. A wide range of therapeutic options are available, including topicals and systemic therapies. Read More

Int J Biol Macromol 2018 Nov 20;119:198-206. Epub 2018 Jul 20.

Laboratoire des Interfaces et des Matériaux Avancés (LIMA), Faculté de Science de Monastir, Université de Monastir, Bd. de l'environnement, 5019 Monastir, Tunisia. Electronic address:

Prunus amygdalus is used in the folk medicine that proved the interest of this plant which cures many diseases. Many researchers are interested to valorize almond waste (hull and shell) and to evaluate their biological and pharmacological activities. In this work, polysaccharides from Prunus amygdalus shell were extracted sequentially by water, ammonium oxalate and hydrochloric acid. Read More

J Cosmet Dermatol 2018 Dec 19;17(6):1136-1143. Epub 2018 Jul 19.

Skin Clinical Research Center, Pierre Fabre Dermo-Cosmetique, Toulouse, France.

Background: Glycolic acid (GA) chemical peels are a popular treatment for photoaged skin rejuvenation, but retinaldehyde (RAL)-based cosmetic creams have also demonstrated efficacy in improving photoaging, and are potentially better tolerated than chemical peels.

Aims: To compare the efficacy and safety of an antiaging cream containing 0.1% RAL associated with Glycylglycine Oleamide (GGO, Relastide ) and Pre-tocopheryl , to GA peels sessions in the treatment of photoaging. Read More

J Anim Physiol Anim Nutr (Berl) 2018 Oct 15;102(5):1284-1295. Epub 2018 Jul 15.

School of Agriculture and Food Technology, Alafua Campus, Apia, Samoa.

The increase demand for poultry products has had direct effect on the supply and price of feed. This has increased research interest into the potential of locally available, less competed and low cost materials as feed ingredients. Several peels from roots/tubers and fruits have been evaluated in poultry diets but recommendations have not been consistent. Read More

J Sci Food Agric 2019 Jan 22;99(2):759-766. Epub 2018 Aug 22.

Food Engineering Department, Engineering Faculty, Gaziantep University, Gaziantep, Turkey.

Background: The processing of tomatoes generates significant amounts of tomato waste, which has a high potential to be used in food industry as a natural food colorant, antioxidant, and food supplement providing health benefits. However, it is difficult to incorporate the carotenoids into different food formulations because they are relatively unstable in food systems. Hence, this novel study investigated the use of an electrospinning technique for the encapsulation of carotenoids extracted from tomato peel into zein nanofibers to improve its thermal and storage stability, and antioxidant activity. Read More

J Drugs Dermatol 2018 Jun;17(6):664-669

Introduction: Several therapeutic modalities from topicals to chemical peels and energy-based devices are available to improve skin quality and reduce the appearance of wrinkles in the face and neck area.

Objective: The objective of this single-center, double blinded, placebo-controlled study was to evaluate the safety and efficacy of Nimni Cream by Hydropeptide® on skin quality and wrinkles.

Methods: 20 patients were randomized in a 3:1 ratio to use either Nimni Cream by Hydropeptide or placebo starting with twice a week application and increasing to daily for 8 weeks. Read More

Int J Biol Macromol 2018 Sep 5;116:128-135. Epub 2018 May 5.

Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:

Low methoxyl (LM) pectin was extracted from pomelo peels using subcritical water in a dynamic mode. The effects of pressure and temperature were analyzed through a face-centred central composite design. Extraction yield and the rate of extraction were found to be predominantly influenced by temperature. Read More

Neurogastroenterol Motil 2018 Jul 2;30(7):e13364. Epub 2018 May 2.

College of Veterinary Medicine, Northeast Agricultural University, Harbin, China.

Background: Pomegranate peels have been widely used to treat diarrhea in China. The antidiarrheal activities of aqueous extracts of pomegranate peels have been evaluated. However, there have not been any bioactivity-guided fractionation studies on the antidiarrheal effect to identify the bioactive components of the extract. Read More

BMJ Open 2018 04 28;8(4):e019607. Epub 2018 Apr 28.

Department of Dermatology & Venereology, West China Hospital, Sichuan University, Chengdu, China.

Objective: We evaluated current evidence from randomised controlled trials (RCTs) regarding the effectiveness of chemical peeling for treating acne vulgaris.

Methods: Standard Cochrane methodological procedures were used. We searched MEDLINE, Cochrane Central Register of Controlled Trials and EMBASE via OvidSP through April 2017. Read More

J Chromatogr Sci 2018 Aug;56(7):644-649

College of Pharmacy, Department of Pharmacy Practice, Fred and Pamela Buffett Cancer Center, University of Nebraska Medical Center, Omaha, NE, USA.

Ultra-performance liquid chromatography (UPLC) interfaced with atmospheric pressure chemical ionization mass-spectrometry was used to separate and quantify ursolic acid (UA) and oleanolic acid (OA) in human plasma. UA and OA were extracted from 0.5 mL human plasma using supported liquid extraction and separated utilizing an Acquity UPLC HSS column. Read More

J Sci Food Agric 2018 Nov 13;98(14):5509-5517. Epub 2018 Jun 13.

Graduate Institute of Immunology, College of Medicine, National Taiwan University, Taipei, Taiwan.

Background: Gold lotion (GL), a natural mixed product made from the peels of six citrus fruits, has recently been identified as possessing anti-oxidative, anti-inflammatory, and immunomodulatory effects. GL has been used to protect skin against UV-induced damage, but its activity against psoriasis, a chronic autoimmune skin disease caused by dysregulation between immune cells and keratinocytes, is not known. We therefore evaluated the effect of GL on imiquimod (IMQ)-induced psoriasis-like inflammation in mice. Read More

Anal Chem 2018 Apr 3;90(8):5232-5238. Epub 2018 Apr 3.

College of Food Science and Engineering , Hefei University of Technology , Hefei , Anhui 230009 , China.

Liquid-state interfacial nanoparticle arrays for surface-enhanced Raman scattering (SERS) promises a practical, substrate-free, and rapid analysis but faces a great challenge to develop a batch and uniform fabrication strategy with stable internal standards (IS) because of the difficulties in precisely locating both the IS tags and analytes in the same local structure under the harsh conditions of biphasic liquid interface. Here, we develop a fast batch preparation of self-ordered dense Au nanoparticle (GNP) arrays on cyclohexane/water biphasic interface in 96-well plates with the assist of acetone as the phase-crossing inducer. The acetone can extract the pesticide molecules via a simple dipping sample peels and can rapidly capture and locate the pesticide molecule into the plasmonic hotspots. Read More