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    Dermal morphological changes following salicylic acid peeling and microdermabrasion.
    J Cosmet Dermatol 2017 Feb 22. Epub 2017 Feb 22.
    Faculty of Medicine, Department of Pathology, Assiut University, Assiut, Egypt.
    Background: Microdermabrasion and chemical peeling are popular, inexpensive, and safe methods for treatment of some skin disorders and to rejuvenate skin.

    Objectives: To study the alterations of the dermal connective tissue following salicylic acid peeling and microdermabrasion.

    Methods: Twenty patients were participated in our study. Read More

    Characterization of major metabolites of polymethoxylated flavonoids in Pericarpium Citri Reticulatae using liver microsomes immobilized on magnetic nanoparticles coupled with UPLC/MS-MS.
    Chem Cent J 2017 6;11:13. Epub 2017 Feb 6.
    0000000119573309grid.9227.eChengdu Institute of Biology, Chinese Academy of Sciences, Chengdu, 610041 Sichuan China.
    The peels of citrus fruits (Pericarpium Citri Reticulatae, PCR) have long been used in traditional Chinese medicines (TCMs). Polymethoxylated flavonoids (PMFs) were found to be the main components present in PCR extracts, but their metabolism remains unclear which restrain the utilization of this TCM. In the present work, rat liver microsomes were immobilized on magnetic nanoparticles (LMMNPs) for in vitro metabolic study on the whole PMFs of PCR. Read More

    A Case of Lichen Planus Pigmentosus with Facial Dyspigmentation Responsive to Combination Therapy with Chemical Peels and Topical Retinoids.
    J Clin Aesthet Dermatol 2016 Nov 1;9(11):44-50. Epub 2016 Nov 1.
    Residency Program Director, New York College of Osteopathic Medicine of New York Institute of Technology, Department of Dermatology, St. Barnabas Hospital, Bronx, New York.
    Lichen planus pigmentosus is a photodistributed dyschromia of unknown etiology described clinically as hyperpigmented gray-blue or brown-black macules or patches in a photodistributed pattern. Although there has been some debate, lichen planus pigmentosus is considered by many to be a separate diagnostic entity from ashy dermatosis or erythema dyschromicum perstans, which shares similar characteristics. Various treatment strategies have been applied to help resolve or improve the appearance of lichen planus pigmentosus lesions; however, an optimal treatment method is yet to be elucidated. Read More

    Polyphenol and Ellagitannin Constituents of Jabuticaba (Myrciaria cauliflora) and Chemical Variability at Different Stages of Fruit Development.
    J Agric Food Chem 2017 Feb 7;65(6):1209-1219. Epub 2017 Feb 7.
    Instituto de Química, Universidade Federal de Goiás , 74690-900, Goiânia, Goiás Brazil.
    A new ellagitannin named cauliflorin (1), seven known hydrolyzable tannins (2-8), and six known phenolics (9-14) were isolated from jabuticaba. Compounds 2-8 had not been previously isolated from M. cauliflora fruits. Read More

    Current Trends in Upper and Lower Eyelid Blepharoplasty Among American Society of Ophthalmic Plastic and Reconstructive Surgery Members.
    Ophthal Plast Reconstr Surg 2017 Feb 1. Epub 2017 Feb 1.
    *Department of Ophthalmology, Byers Eye Institute, Stanford University School of Medicine, Palo Alto, †Department of Otolaryngology-Head and Neck Surgery, Division of Facial Plastic and Reconstructive Surgery, Keck School of Medicine, University of Southern California, Los Angeles, ‡David Geffen School of Medicine at the University of California, Los Angeles, §Division of Facial Plastic Surgery, Beverly Hills, ‖Division of Head & Neck Surgery, David Geffen School of Medicine at the University of California, Los Angeles, ¶Center for Advanced Facial Plastic Surgery, Beverly Hills, #Department of Ophthalmology, Keck School of Medicine, University of Southern California, Los Angeles, and **Division of Ophthalmic Plastic and Reconstructive Surgery, Beverly Hills Ophthalmic Plastic Surgery, Beverly Hills, California, U.S.A.
    Purpose: To assess current practice patterns for management of upper and lower eyelid blepharoplasty by active American Society of Ophthalmic Plastic and Reconstructive Surgery members.

    Methods: An invitation to participate in a web-based anonymous survey was sent to the active American Society of Ophthalmic Plastic and Reconstructive Surgery membership via email. The survey consists of 34 questions, both multiple choice and free response, regarding upper and lower eyelid blepharoplasty surgery. Read More

    Universal Trichloroacetic Acid Peel Technique for Light and Dark Skin.
    JAMA Facial Plast Surg 2017 Jan 12. Epub 2017 Jan 12.
    Department of Dermatology, McGill University, Montreal, Quebec, Canada.
    Importance: Despite their great potential, medium and deep trichloroacetic acid peels are underused in light-skinned patients and are rarely used in darker-skinned patients because of the widespread fear of pigmentary complications and scarring. This concern has led many physicians to opt for the use of lighter types of peels (glycolic acid peel, Jessner peel, etc) and different lasers and intense light technologies. Trichloroacetic acid peels have been described in numerous publications. Read More

    Combination Therapy for Acne Scarring: Personal Experience and Clinical Suggestions.
    J Drugs Dermatol 2016 Nov;15(11):1413-1419
    Acne is one of the most prevalent skin conditions seen by dermatologists. The cosmetic sequelae of severe acne, including scarring and pigmentation, have a profound psychological impact on those in icted. Topical (eg, retinoids, antibiotics, dapsone, hydroxyacids) and oral treatments (eg, antibiotics and/or spironolactone) are often bene cial to control acne or in the instance of oral isotretinoin use, rid the acne permanently; however, these treatments have very little affect on the ultimate cosmetic outcome of the acne scarring and skin texture that results. Read More

    Evaluation of different training systems on Annurca apple fruits revealed by agronomical, qualitative and NMR-based metabolomic approaches.
    Food Chem 2017 May 29;222:18-27. Epub 2016 Nov 29.
    Consiglio per la Ricerca in Agricoltura e l'analisi dell'Economia Agraria (CREA), Unità di ricerca per la Frutticoltura, Via Torrino 3, I-81100 Caserta, Italy. Electronic address:
    Nine different training systems for "Annurca Rossa del Sud" apple fruits, including oblique palmette, free palmette, V-shaped, Tatura trellis, Bibaum®, modified Bibaum®, triple leader, slender spindle and Solaxe, were evaluated based on agronomic, qualitative and metabolomic traits. Fruits were analysed at harvest and after the reddening process. The slender spindle training system showed the highest cumulative efficiency yield compared to the others. Read More

    Composition, bioactive compounds and antioxidant activity of common Indian fruits and vegetables.
    J Food Sci Technol 2016 Nov 25;53(11):4056-4066. Epub 2016 Nov 25.
    Department of Food Science and Technology, Guru Nanak Dev University, Amritsar, Punjab 143005 India.
    The present work was undertaken to evaluate the chemical composition (proximate, minerals and dietary fibre), colour parameters, antioxidant activity and polyphenol profiles of different fruits (pomegranate, kinnow, mango, banana, jambolan, grapes and sapodilla) and vegetables (beetroot, brinjal, orange carrot, bitter gourd, mentha and spinach). The amount of insoluble dietary fibre was higher than soluble dietary fibre for all fruits and vegetables. Vegetables showed superior mineral composition (higher amounts of K, Ca and Fe) as compared to fruits. Read More

    Randomized controlled trial comparing 35% trichloroacetic acid peel and 5-aminolevulinic acid photodynamic therapy for the treatment of multiple actinic keratosis.
    Br J Dermatol 2016 Dec 23. Epub 2016 Dec 23.
    Department of Dermatology, Medical University of Vienna.
    Background: Photodynamic therapy (PDT) and chemical peels with trichloroacetic acid (TCA) can be applied to larger skin areas and thus are suitable treatment options for patients with multiple actinic keratosis (AK). Despite its long use TCA has, however, only been investigated rarely in this indication.

    Objectives: This randomized, observer-blinded, intrapatient comparison study sought to investigate the efficacy and safety of 35% TCA versus 20% aminolevulinic acid PDT (ALA PDT) in patients with extensive field cancerisation and multiple AK in the face or on the scalp. Read More

    Literature Review of Cosmetic Procedures in Men: Approaches and Techniques are Gender Specific.
    Am J Clin Dermatol 2017 Feb;18(1):87-96
    Department of Dermatology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Ezralow Tower 5301, Los Angeles, CA, 90033, USA.
    The proportion of men receiving non-surgical cosmetic procedures has risen substantially in recent years. Various physiologic, anatomic, and motivational considerations differentiate the treatments for male and female patients. Nevertheless, research regarding approaches to the male cosmetic patient is scarce. Read More

    Study on optimization of process parameters for enhancing the multi-hydrolytic enzyme activity in garbage enzyme produced from preconsumer organic waste.
    Bioresour Technol 2017 Feb 9;226:200-210. Epub 2016 Dec 9.
    Department of Chemical Engineering, National Institute of Technology, Tiruchirappalli, Tamil Nadu 620015, India. Electronic address:
    The garbage enzymes produced from preconsumer organic waste containing multi hydrolytic enzyme activity which helps to solubilize the waste activated sludge. The continuous production of garbage enzyme and its scaling up process need a globe optimized condition. In present study the effect of fruit peel composition and sonication time on enzyme activity were investigated. Read More

    A Limonoid Kihadanin B from Immature Citrus unshiu Peels Suppresses Adipogenesis through Repression of the Akt-FOXO1-PPARγ Axis in Adipocytes.
    J Agric Food Chem 2016 Dec 15;64(51):9607-9615. Epub 2016 Dec 15.
    Laboratory of Biodefense and Regulation, Osaka University of Pharmaceutical Sciences , 4-20-1 Nasahara, Takatsuki, Osaka 569-1094, Japan.
    Citrus limonoids are secondary metabolites and exhibit a variety of biological activities. In this study, we elucidated the suppression of adipogenesis by a Citrus limonoid kihadanin B and determined its molecular mechanism in mouse 3T3-L1 adipocytes. Kihadanin B was purified from the peels of immature Citrus unshiu by HPLC, and its chemical structure was determined by NMR and mass spectrometry. Read More

    Pectinase production by Aspergillus giganteus in solid-state fermentation: optimization, scale-up, biochemical characterization and its application in olive-oil extraction.
    J Ind Microbiol Biotechnol 2017 Feb 22;44(2):197-211. Epub 2016 Nov 22.
    Instituto de Investigaciones Biotecnológicas-Instituto Tecnológico de Chascomús (IIB-INTECH), Universidad Nacional de San Martín (UNSAM)-Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), San Martín, Buenos Aires, Argentina.
    The application of pectinases in industrial olive-oil processes is restricted by its production cost. Consequently, new fungal strains able to produce higher pectinase titers are required. The aim of this work was to study the capability of Aspergillus giganteus NRRL10 to produce pectinolytic enzymes by SSF and evaluate the application of these in olive-oil extraction. Read More

    Remediation of Cu metal-induced accelerated Fenton reaction by potato peels bio-sorbent.
    Environ Monit Assess 2016 Dec 16;188(12):674. Epub 2016 Nov 16.
    Department of Chemistry, University of Karachi, Karachi, 75270, Pakistan.
    This article has allied exposure to Ecological Particulate Matter (EPM) and its remediation using potato peel surface (PPC) bio-sorbent on two important edible crops Spinacia oleracea and Luffa acutangula. Fenton reaction acceleration was one of the major stress oxidation reactions as a consequence of iron and copper toxicity, which involve in the formation of hydroxyl radical (OH) through EPM. Results showed that the oxidative stress encouraged by Cu in both species that recruits the degradation of photosynthetic pigments, initiating decline in growth, reduced leaf area and degrade proteins. Read More

    Physical, Chemical and Proteomic Evidence of Potato Suberin Degradation by the Plant Pathogenic Bacterium Streptomyces scabiei.
    Microbes Environ 2016 Dec 17;31(4):427-434. Epub 2016 Nov 17.
    Centre SÈVE, Département de Biologie, Université de Sherbrooke.
    Potato peels consist of a tissue called phellem, which is formed by suberized cell layers. The degradation of suberin, a lipidic and recalcitrant polymer, is an ecological process attributed to soil fungal populations; however, previous studies have suggested that Streptomyces scabiei, the causal agent of potato common scab, possesses the ability to degrade suberin. In the present study, S. Read More

    Sequential ultrasound-microwave assisted acid extraction (UMAE) of pectin from pomelo peels.
    Int J Biol Macromol 2016 Dec 24;93(Pt A):426-435. Epub 2016 Aug 24.
    Department of Chemical Engineering, Faculty of Engineering, University of Malaya, 50603 Kuala Lumpur, Malaysia. Electronic address:
    This study aims to optimize sequential ultrasound-microwave assisted extraction (UMAE) on pomelo peel using citric acid. The effects of pH, sonication time, microwave power and irradiation time on the yield and the degree of esterification (DE) of pectin were investigated. Under optimized conditions of pH 1. Read More

    Yield and composition of pectin extracted from Tunisian pomegranate peel.
    Int J Biol Macromol 2016 Dec 11;93(Pt A):186-194. Epub 2016 Aug 11.
    Laboratoire Analyse, Valorisation et Sécurité des Aliments, Université de Sfax, Ecole Nationale d'Ingénieurs de Sfax (ENIS), BP 3038, Sfax, Tunisia. Electronic address:
    A central composite design was employed to determine the influence of extraction conditions on production yield and chemical composition of pectin from pomegranate peels. Response surface methodology (RSM) was used to quantify the integral effect of the three processing parameters (extraction duration, temperature and pH) on yield. A second-order polynomial model was developed for predicting the yield of pomegranate peels pectin based on the composite design. Read More

    Antimicrobial effect of the Tunisian Nana variety Punica granatum L. extracts against Salmonella enterica (serovars Kentucky and Enteritidis) isolated from chicken meat and phenolic composition of its peel extract.
    Int J Food Microbiol 2017 Jan 11;241:123-131. Epub 2016 Oct 11.
    Unité de recherche Toxicologie - Microbiologie Environnementale et Santé (UR11ES70), Faculté des Sciences de Sfax, Université de Sfax-Tunisie, Sfax, Tunisie. Electronic address:
    Punica granatum L. is widely recognized for its potency against a broad spectrum of bacterial pathogens. The purpose of this study was to explore the inhibitory and the bactericidal activities of Punica granatum against Salmonella strains. Read More

    Comparative biogas generation from fruit peels of fluted pumpkin (Telfairia occidentalis) and its optimization.
    Bioresour Technol 2016 Dec 20;221:517-525. Epub 2016 Sep 20.
    Chemical Engineering Department, Covenant University, Ota, Ogun State, Nigeria.
    This study evaluated the potentials of fluted pumpkin fruit peels for biogas generation using three different pre-treatment methods (A, B, C) and the optimization of its process parameters. The physic-chemical characteristics of the substrates revealed it to be rich in nutrients and mineral elements needed by microorganisms. Gas chromatography analysis revealed the gas composition to be within the range of 58. Read More


    Preventing, identifying, and managing cosmetic procedure complications, part 2: lasers and chemical peels.
    Cutis 2016 Aug;98(2):E27-8
    Department of Dermatology, University of California, San Diego, USA.
    Part 1 of this series highlighted some of the potential complications that have been associated with soft tissue augmentation and botulinum toxin injections. In part 2, tips for how dermatology residents may prevent, identify, and manage complications from lasers and chemical peels for optimal patient outcomes are provided. Read More

    The Effects of a Daily Skincare Regimen on Maintaining the Benefits Obtained from Previous Chemical Resurfacing Treatments.
    J Drugs Dermatol 2016 Sep;15(9):1145-50
    Background: Chemical peels are versatile treatments that involve chemical exfoliation of the skin for cosmetic improvement. Deeper peels produce more significant results, but can be associated with longer healing time and potential complications. Novel chemical resurfacing treatments (AGE and MELA) were developed in Europe to produce skin resurfacing via controlled inflammation to promote cell regeneration with minimum negative effects associated with conventional peelings. Read More

    Characterization and lead(II) ions removal of modified Punica granatum L. peels.
    Int J Phytoremediation 2017 Apr;19(4):327-339
    b Department of Chemistry , Faculty of Science, Anadolu University , Eskişehir , Turkey.
    The aim of the present study was to enhance the biosorption capacity of a waste biomass of Punica granatum L. peels (PGL) using various chemical modification agents. Among these agents, hexamethylenediamine (HMDA) indicated the best performance with regard to the improvement of lead(II) ions removal from aqueous solution. Read More

    Melasma.
    G Ital Dermatol Venereol 2017 02 2;152(1):36-45. Epub 2016 Sep 2.
    Departments of Dermatology and Pathology, Rutgers University New Jersey Medical School, Newark, NJ, USA -
    Melasma is a common acquired hypermelanosis that primarily affects women of skin type IV-VI. It tends to appear on sun-exposed areas of face and neck. The exact pathogenesis is linked with many factors include ultraviolet radiation, pregnancy, hormonal activity, thyroid abnormalities, and medications. Read More

    Application of banana peels nanosorbent for the removal of radioactive minerals from real mine water.
    J Environ Radioact 2016 Nov 15;164:369-376. Epub 2016 Sep 15.
    SARChI Chair for Mine Water Management, Department of Environmental, Water, and Earth Sciences, Tshwane University of Technology, Pretoria, 0001, South Africa; Lappeenranta University of Technology, Laboratory of Green Chemistry, Sammonkatu 12, 50130, Mikkeli, Finland.
    Transformation of agricultural waste such as banana peels into a valuable sorbent material has been proven effective and efficient in wastewater treatment. Further, transformation into nanosorbent to enhance the removal capacity of actinides (uranium and thorium) from synthetic and real mine water is extensively investigated in this study. The nanosorbent samples before and after adsorption were characterised by X-ray diffraction (XRD), Fourier transform infra-red (FTIR), zetasizer nanoseries and scanning electron microscopy (SEM) while the amount of radioactive substances adsorbed was determined by inductively coupled plasma optical emission spectroscopy. Read More

    Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.
    J Cosmet Dermatol 2016 Aug 25. Epub 2016 Aug 25.
    Department of Dermatology, Venereology and Leprology, Pt B D Sharma University of Health Sciences, Rohtak, Haryana, India.
    Introduction: Chemical peeling is a well-identified therapeutic modality for acne vulgaris (AV). Jessner's solution (JS) is a known peeling agent for acne since more than 100 years. Salicylic acid (SA) peel is a well-established peeling agent for acne. Read More

    Characterization of pectins extracted from pomegranate peel and their gelling properties.
    Food Chem 2017 Jan 30;215:318-25. Epub 2016 Jul 30.
    Laboratoire Analyse, Valorisation et Sécurité des Aliments, Université de Sfax, Ecole Nationale d'Ingénieurs de Sfax (ENIS), BP 1173-3038 Sfax, Tunisia. Electronic address:
    The composition of pomegranate peel, the main by-product during pomegranate processing, and some of the characteristics of the water-soluble pectins were investigated. Four tunisian pomegranate peels were subjected to hot aqueous extractions (86°C, 80min, 20mM nitric acid). Pomegranate peels yielded between 6. Read More

    Essential oil components of orange peels and antimicrobial activity.
    Nat Prod Res 2017 Mar 18;31(6):653-659. Epub 2016 Aug 18.
    b Dipartimento di Scienze Agrarie e Forestali (SAF) Università di Palermo Viale delle Scienze , Palermo , Italy.
    In this study, the orange peel of 12 cultivars of Citrus sinensis from central-eastern Sicily was employed to obtain essential oils and extracts. The ones were extracted through steam distillation, the others through extraction in hexane. Chemical constituents were evaluated in terms of qualitative and quantitative analyses by gas chromatography/mass spectrometry. Read More

    Enlarged facial pores: an update on treatments.
    Cutis 2016 Jul;98(1):33-6
    Department of Dermatology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
    Enlarged facial pores remain a common dermatologic and cosmetic concern from acne and rosacea, among other conditions, that is difficult to treat due to the multifactorial nature of their pathogenesis and negative impact on patients' quality of life. Enlarged facial pores are primarily treated through addressing associative factors, such as increased sebum production and cutaneous aging. We review the current treatment modalities for enlarged or dense facial pores, including topical retinoids, chemical peels, oral antiandrogens, and lasers and devices, with a focus on newer therapies. Read More

    Deficit irrigation and maturation stage influence quality and flavonoid composition of 'Valencia' orange fruit.
    J Sci Food Agric 2016 Aug 16. Epub 2016 Aug 16.
    Department of Agricultural and Forest Sciences, University of Palermo, Italy.
    Background: Effects of continuous deficit irrigation (DI) and partial rootzone drying (PRD) treatments (50% ETc) in comparison with full irrigation (CI, 100% ETc) were investigated during 'Valencia' orange fruit maturation. Ultra-high-performance liquid chromatography/high-resolution mass spectrometry was used to quantify hesperidin, narirutin, tangeritin, nobiletin, didymin and neoeriocitrin in the fruit juice and peel.

    Results: No significant effect of irrigation was found on yield, juice soluble solids or acidity. Read More

    Noninvasive Facial Rejuvenation. Part 3: Physician-Directed-Lasers, Chemical Peels, and Other Noninvasive Modalities.
    Semin Plast Surg 2016 Aug;30(3):143-50
    Nigro Dermatology Group, Houston, Texas.
    A proper knowledge of noninvasive facial rejuvenation is integral to the practice of a cosmetic surgeon. Noninvasive facial rejuvenation can be divided into patient- versus physician-directed modalities. Patient-directed facial rejuvenation combines the use of facial products such as sunscreen, moisturizers, retinoids, α-hydroxy acids, and various antioxidants to both maintain youthful skin and rejuvenate damaged skin. Read More

    Noninvasive Facial Rejuvenation. Part 2: Physician-Directed-Neuromodulators and Fillers.
    Semin Plast Surg 2016 Aug;30(3):134-42
    Nigro Dermatology Group, Houston, Texas.
    A proper knowledge of noninvasive facial rejuvenation is integral to the practice of a cosmetic surgeon. Noninvasive facial rejuvenation can be divided into patient- versus physician-directed modalities. Patient-directed facial rejuvenation combines the use of facial products such as sunscreen, moisturizers, retinoids, α-hydroxy acids, and various antioxidants to both maintain youthful skin as well as rejuvenate damaged skin. Read More

    Noninvasive Facial Rejuvenation. Part 1: Patient-Directed.
    Semin Plast Surg 2016 Aug;30(3):129-33
    Division of Plastic Surgery, Baylor College of Medicine, Houston, Texas.
    A proper knowledge of noninvasive facial rejuvenation is integral to the practice of a cosmetic surgeon. Noninvasive facial rejuvenation can be divided into patient- versus physician-directed modalities. Patient-directed facial rejuvenation combines the use of facial products such as sunscreen, moisturizers, retinoids, α-hydroxy acids, and various antioxidants to both maintain youthful skin and rejuvenate damaged skin. Read More

    Preventing, identifying, and managing cosmetic procedure complications, part 1: soft-tissue augmentation and botulinum toxin injections.
    Cutis 2016 Jun;97(6):E28-9
    Department of Dermatology, University of California, San Diego, USA.
    This column highlights some of the potential complications that have been associated with cosmetic procedures. Tips for how dermatology residents may prevent, identify, and manage complications from cosmetic procedures for optimal patient outcomes is provided. In part 1 of this series, soft-tissue augmentation and botulinum toxin injections are discussed. Read More

    Integrative Approach for Producing Hydrogen and Polyhydroxyalkanoate from Mixed Wastes of Biological Origin.
    Indian J Microbiol 2016 Sep 10;56(3):293-300. Epub 2016 May 10.
    Microbial Biotechnology and Genomics, CSIR-Institute of Genomics and Integrative Biology (IGIB), Delhi University Campus, Mall Road, Delhi, 110007 India.
    In this study, an integrative approach to produce biohydrogen (H2) and polyhydroxyalkanoates (PHA) from the wastes of biological origin was investigated. A defined set of mixed cultures was used for hydrolysis and the hydrolysates were used to produce H2. The effluent from H2 production stage was used for PHA production. Read More

    Surgical Outcome in Patients Taking Concomitant or Recent Intake of Oral Isotretinoin: A Multicentric Study-ISO-AIMS Study.
    J Cutan Aesthet Surg 2016 Apr-Jun;9(2):106-14
    Skinnovation Laser Clinic, New Delhi, India.
    Background: The current standard recommendation is to avoid surgical interventions in patients taking oral isotretinoin. However, this recommendation has been questioned in several recent publications.

    Aim: To document the safety of cosmetic and surgical interventions, among patients receiving or recently received oral isotretinoin. Read More

    Evaluation of Various Therapeutic Measures in Striae Rubra.
    J Cutan Aesthet Surg 2016 Apr-Jun;9(2):101-5
    Department of Dermatology, B.J. Medical College, Ahmedabad, Gujarat, India.
    Background: Striae are linear atrophic depressions that form in areas of dermal damage in the skin. As on date, no consensus or protocol exists for the treatment of stria rubra. Topical retinoids, chemical peels, microdermabrasion, radiofrequency, photothermolysis, intense pulsed light and lasers are some of the modalities used. Read More

    Chemical Composition and Bioactivities of Two Common Chaenomeles Fruits in China: Chaenomeles speciosa and Chaenomeles sinensis.
    J Food Sci 2016 Aug 6;81(8):H2049-58. Epub 2016 Jul 6.
    Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency, School of Pharmaceutical Science and Technology, Tianjin Univ, No. 92 Weijin Road, Nankai District, Tianjin, 300072, China.
    Contents of total flavonoids, total phenolics, total triterpenes, total condensed tannin and total saponins in peels, flesh and endocarps of Chaenomeles speciosa (CSP) and Chaenomeles sinensis (CSS) were determined by colorimetric method, while 5 phenolics (vanillic, gallic, chlorogenic, ferulic and p-coumaric acids), 2 triterpenes (oleanolic and ursolic acids), and 3 flavonoids (rutin, catechin and epicatechin) were identified and quantified by high-performance liquid chromatography-mass spectrometry (HPLC-MS) and HPLC, and antioxidant and α-glucosidase inhibitory activities of them also were evaluated as well as their digestive characteristics. In the correlation analysis, total phenolics, vanillic acid, catechin, ursolic acid and oleanolic acid all contribute to DPPH(·) scavenge capacity, gallic acid contributes to total ferric reducing antioxidant power, while total triterpenes, total saponins, chlorogenic acid and ferullic acid contribute to α-glucosidase inhibitory activity. In the principal component analysis, endocarps of CSP and CSS both show better quality than their peels and flesh, respectively. Read More

    Clinical efficacy and safety of 20% glycolic peel, 15% lactic peel, and topical 20% vitamin C in constitutional type of periorbital melanosis: a comparative study.
    J Cosmet Dermatol 2016 Dec 6;15(4):367-373. Epub 2016 Jul 6.
    Department of Dermatology, Venereology and Leprology, Pt B D Sharma University of Health Sciences, Rohtak, Haryana, India.
    Introduction: Periorbital Melanosis (POM) is a very common esthetic condition, yet there is no definite treatment modality. Topical therapy is the mainstay of treatment which includes chemical peels, vitamin C, and other depigmenting agents.

    Objective: To compare clinical efficacy, safety, and tolerability of 20% glycolic acid peels, 15% lactic acid peels, and topical 20% vitamin C in treatment of constitutional type of POM in Indian patients. Read More

    Elimination of textile dyes using activated carbons prepared from vegetable residues and their characterization.
    J Environ Manage 2016 Oct 5;181:269-78. Epub 2016 Aug 5.
    Facultad de Ingeniería, Benemérita Universidad Autónoma de Puebla, Edificio ING1, Ciudad Universitaria, CP. 72570 Puebla, Mexico.
    In this study, three mesoporous activated carbons prepared from vegetable residues were used to remove acid, basic, and direct dyes from aqueous solutions, and reactive and vat dyes from textile wastewater. Granular carbons obtained by chemical activation at 673 K with phosphoric acid from prickly pear peels (CarTunaQ), broccoli stems (CarBrocQ), and white sapote seeds (CarZapQ) were highly efficient for the removal of dyes. Adsorption equilibrium studies were carried out in batch systems and treated with Langmuir and Freundlich isotherms. Read More

    Mesotherapy, Microneedling, and Chemical Peels.
    Clin Plast Surg 2016 Jul 11;43(3):583-95. Epub 2016 May 11.
    Division of Plastic Surgery, Albany Medical Center, 50 New Scotland Avenue, MC-190, Albany, NY 12208, USA.
    Mesotherapy, microneedling, and chemical peels are minimally invasive techniques used to combat facial aging. Chemical peeling is one of the oldest methods of facial rejuvenation. By using different chemicals in various combinations, strengths, and application techniques, plastic surgeons can tailor a patient's treatment for optimal, safe, and consistent results. Read More

    The PAVE (peeling-assisted volume-enhancing) lift: A retrospective 6-year clinical analysis of a combined approach for facial rejuvenation.
    J Plast Reconstr Aesthet Surg 2016 Aug 4;69(8):1128-33. Epub 2016 May 4.
    Centre for Plastic and Aesthetic Surgery, Ocean Clinic, Marbella, Malaga, Spain; Department for Plastic, Reconstructive, Hand and Burns Surgery, BG-Trauma Centre, Schnarrenbergstrasse, Tuebingen, Baden-Wuerttemberg, Germany. Electronic address:
    The peeling-assisted volume-enhancing (PAVE) lift is a single-stage approach that combines superficial musculoaponeurotic system (SMAS) plication techniques with fat grafting and different peeling agents. To evaluate the safety of this approach, we analyzed the records of 159 patients who underwent surgery between 2008 and 2014. The percentage of complications observed was not higher than values reported in the literature for each treatment entity: surgical facelift: n=3 haematomas (1. Read More

    Mesophilic anaerobic co-digestion of poultry dropping and Carica papaya peels: Modelling and process parameter optimization study.
    Bioresour Technol 2016 Sep 30;216:587-600. Epub 2016 May 30.
    Chemical Engineering Department, Covenant University, Nigeria.
    The study evaluated anaerobic co-digestion of poultry dropping and pawpaw peels and the optimization of important process parameters. The physic-chemical analyses of the substrates were done using standard methods after application of mechanical, thermal and chemical pre-treatments methods. Gas chromatography analysis revealed the gas composition to be within the range of 66-68% methane and 18-23% carbon dioxide. Read More

    Characterization and functional properties of mango peel pectin extracted by ultrasound assisted citric acid.
    Int J Biol Macromol 2016 Oct 6;91:794-803. Epub 2016 Jun 6.
    College of Food Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, PR China; Key Laboratory of Environment Correlative Dietology, Ministry of Education, PR China. Electronic address:
    Pectin was extracted from 'Tainong No. 1' mango peels, using a chelating agent-citric acid as extraction medium by ultrasound-assisted extraction (UAE) and conventional extraction (CE) at temperatures of 20 and 80°C. Chemical structures, rheological and emulsifying properties of mango peel pectins (MPPs) were comparatively studied with laboratory grade citrus pectin (CP). Read More

    A Simple and Rapid HPLC-PDA MS Method for the Profiling of Citrus Peels and Traditional Italian Liquors.
    Planta Med 2016 Jul 9;82(11-12):1039-45. Epub 2016 Jun 9.
    University of Florence, Department of Chemistry, Sesto Fiorentino, Via Ugo Schiff 6, 50019, Florence, Italy.
    A chromatographic method for the qualitative and quantitative characterization of peels and preparations based on different species of Citrus was developed in order to obtain a complete profile of the constituents, including flavonoids and protoalkaloids. Commercial peels of sweet orange, lemon, mandarin, and grapefruit were analyzed. Seventeen constituents including flavanones, flavones, polymethoxyflavones, and protoalkaloids were identified by HPLC-PDA, HPLC-MS, and HPLC-MS/MS using a comparison of retention times and UV-Vis and MS spectra with reference standards and literature data. Read More

    Epigenetic modifications of triterpenoid ursolic acid in activating Nrf2 and blocking cellular transformation of mouse epidermal cells.
    J Nutr Biochem 2016 Jul 28;33:54-62. Epub 2015 Sep 28.
    Center for Cancer Prevention Research, Ernest Mario School of Pharmacy, Piscataway, NJ 08854, USA; Department of Pharmaceutics, Earnest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ 08854, USA. Electronic address:
    Ursolic acid (UA), a well-known natural triterpenoid found in abundance in blueberries, cranberries and apple peels, has been reported to possess many beneficial health effects. These effects include anticancer activity in various cancers, such as skin cancer. Skin cancer is the most common cancer in the world. Read More

    Ways of Noninvasive Facial Skin Tightening and Fat Reduction.
    Facial Plast Surg 2016 Jun 1;32(3):276-82. Epub 2016 Jun 1.
    Department of Paediatric Dermatology, Colentina Clinica Hospital, Carol Davila University of Medicine and Pharmacy, Bucharest, Romania.
    For skin tightening, ablative and nonablative lasers have been used with various parameters full or fractionated. Currently, other energy-based technologies have been developed such as radiofrequency (RF) from mono- to multipolar, microneedling RF, and high-intensity focused ultrasound. They heat up the tissue to a clinical endpoint. Read More

    Bio-therapeutic Potential and Cytotoxicity Assessment of Pectin-Mediated Synthesized Nanostructured Cerium Oxide.
    Appl Biochem Biotechnol 2016 Oct 27;180(4):638-654. Epub 2016 May 27.
    Department of Microbiology, School of Life Sciences, North Maharashtra University, Umavi Nagar, Post Box 80, Jalgaon, 425 001, India.
    In the present studies, renewable and nontoxic biopolymer, pectin, was extracted from Indian red pomelo fruit peels and used for the synthesis of cerium oxide nanoparticles (CeO2-NPs) having bio-therapeutic potential. The structural information of extracted pectin was investigated by FTIR and NMR spectroscopic techniques. Physicochemical characteristics of this pectin suggested its application in the synthesis of metal oxide nanoparticles. Read More

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