2,016 results match your criteria Chang Gung medical journal[Journal]


Leiomyosarcoma of the adrenal vein.

Chang Gung Med J 2012 Sep-Oct;35(5):428-31

Division of Urology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Leiomyosarcoma of the adrenal gland is extremely rare in the literature. We present a patient with an adrenal leiomyosarcoma originating from the adrenal vein, the pathologic findings and management. A 66-year-old man who was a hepatitis B virus carrier was found to have a huge left suprarenal mass on sonography and computed axial tomography. Read More

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http://dx.doi.org/10.4103/2319-4170.105475DOI Listing
November 2013
5 Reads

Chemotherapy with gemcitabine plus cisplatin in patients with advanced biliary tract carcinoma at Chang Gung Memorial Hospital: a retrospective analysis.

Chang Gung Med J 2012 Sep-Oct;35(5):420-7

Division of Hematology-Oncology, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: A gemcitabine-cisplatin combination is a standard treatment option for patients with advanced biliary tract carcinoma (BTC). We assessed the efficacy and safety of this regimen at Chang Gung Memorial Hospital.

Methods: Between April 2009 and December 2010, 30 chemotherapy-naïve patients (13 men and 17 women; median age: 61. Read More

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http://dx.doi.org/10.4103/2319-4170.105476DOI Listing
November 2013
49 Reads

Team innovation climate and knowledge sharing among healthcare managers: mediating effects of altruistic intentions.

Chang Gung Med J 2012 Sep-Oct;35(5):408-19

Graduate Institute of Business and Management, Chang Gung University, Taoyuan, Taiwan.

Background: This paper aims to provide empirical evidence concerning the impact of team climate on knowledge sharing behavior and the mediating effects of individuals' altruistic intentions in the context of healthcare settings.

Methods: Questionnaire data were collected from 212 administrators employed at a medical center in Taiwan. Team climate was assessed by the Team Climate Inventory composed of four factors, participative safety, support for innovation, vision, and task orientation. Read More

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http://dx.doi.org/10.4103/2319-4170.105477DOI Listing
November 2013
5 Reads

Everolimus in metastatic renal cell carcinoma: preliminary experience from Chang Gung Memorial Hospital.

Chang Gung Med J 2012 Sep-Oct;35(5):402-7

Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Everolimus has been approved for second-line treatment of patients with metastatic renal cell carcinoma (mRCC) after failure of sorafenib or sunitinib. The purpose of this retrospective study was to assess the efficacy and safety of everolimus in Taiwanese patients with mRCC.

Methods: Between March 2009 and August 2011, 24 mRCC patients treated with everolimus were analyzed. Read More

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http://dx.doi.org/10.4103/2319-4170.105478DOI Listing
November 2013
17 Reads

Factors associated with strain in informal caregivers of stroke patients.

Chang Gung Med J 2012 Sep-Oct;35(5):392-401

Department of Rehabilitation, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

Background: Stroke is one of the most prevalent causes of adult disability and handicap. Informal caregivers play an important role in poststroke care. However, informal caregivers may experience strain, which threatens the recovery of stroke subjects. Read More

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http://dx.doi.org/10.4103/2319-4170.105479DOI Listing
November 2013
73 Reads

Serum lipid profile could predict the inception and impacts of violent behaviors among acute psychiatric inpatients.

Chang Gung Med J 2012 Sep-Oct;35(5):382-91

Department of Health Care Administration, Oriental Institute of Technology, New Taipei City, Taiwan.

Background: The prediction of violence among psychiatric inpatients using biophysiological indicators is warranted for re-examinations longitudinally. This study aims to explore factors associated with the occurrence of violence and subsequent medical impacts in psychiatric inpatients.

Methods: Inpatients diagnosed with either schizoaffective disorder or bipolar mania were admitted to acute wards in a professional psychiatric care setting. Read More

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http://dx.doi.org/10.4103/2319-4170.105480DOI Listing
November 2013
7 Reads

Comparison of respiratory parameters and plasma cytokine levels between treatment with Salmeterol/fluticasone and ipratropium/terbutaline/budesonide in mechanically ventilated COPD patients.

Chang Gung Med J 2012 Sep-Oct;35(5):373-81

Division of Pulmonary, Critical Care and Sleep Medicine, Chang Gung Memorial Hospital at Keelung, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: It is unknown whether the bronchodilation and anti-inflammatory effects of inhaled salmeterol and fluticasone (SF) are better than those of traditionally inhaled ipratropium, terbutaline and budesonide (ITB) in mechanically ventilated patients with chronic obstructive pulmonary disease (COPD).

Methods: Nineteen stable COPD patients with respiratory failure were randomly enrolled into two groups. Patients were treated with inhaled SF delivered by a metered-dose inhaler with a spacer or with inhaled nebulized ITB. Read More

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http://dx.doi.org/10.4103/2319-4170.105481DOI Listing
November 2013
3 Reads

The diagnosis and treatment of neonatal seizures.

Authors:
Akihisa Okumura

Chang Gung Med J 2012 Sep-Oct;35(5):365-72

Department of Pediatrics, Juntendo University Faculty of Medicine, Tokyo, Japan.

The occurrence of neonatal seizures is an important clinical sign indicating brain disorder in neonates. An identification of neonatal seizures is critical in the management of high risk neonates. However, the diagnosis and management of neonatal seizures are challenging, because electroclinical dissociation is an outstanding feature of neonatal seizures. Read More

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http://dx.doi.org/10.4103/2319-4170.105482DOI Listing
November 2013
9 Reads

A rare case of spontaneous resolution of eosinophilic ascites in a patient with primary eosinophilic gastroenteritis.

Chang Gung Med J 2012 Jul-Aug;35(4):354-9

Division of Gastroenterology, Department of Internal Medicine, Chang Gung Memorial Hospital at Chiayi, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Eosinophilic gastroenteritis is a rare gastrointestinal disorder characterized by nonspecific gastrointestinal symptoms, peripheral eosinophilia, and eosinophilic infiltration of the intestinal wall. The disorder is classified into mucosal, muscular, and subserosal types, depending on the depth of eosinophilic infiltration within the gastrointestinal wall, and the clinical picture varies accordingly. Subserosal disease, which is complicated by ascites, usually results in the most severe clinical form of eosinophilic gastroenteritis and mandates early corticosteroid therapy. Read More

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http://dx.doi.org/10.4103/2319-4170.106134DOI Listing
May 2013
50 Reads

Complications of cement-augmented dynamic hip screws in unstable type intertrochanteric fractures--a case series study.

Chang Gung Med J 2012 Jul-Aug;35(4):345-53

Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chiayi, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Polymethylmethacrylate (PMMA) cement-augmented dynamic hip screws (DHS) have been used as a solution in unstable intertrochanteric fractures (ITF). Our aim was to investigate the complications in PMMA cement-augmented DHS.

Methods: All patients who had received DHS plate osteosynthesis with or without PMMA cement augmentation from August 2005 to July 2009 in one medical center were retrospectively reviewed. Read More

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http://memo.cgu.edu.tw/cgmj/3504/350407.pdf
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http://dx.doi.org/10.4103/2319-4170.106135DOI Listing
May 2013
6 Reads

Temporary vesicostomy-assisted urethroplasty for recurrent obliterated posterior urethral stricture.

Chang Gung Med J 2012 Jul-Aug;35(4):339-44

Division of Urology, Department of Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: We report the outcomes of temporary vesicostomy- assisted anastomotic urethroplasty in patients with recurrent obliterated posterior urethral stricture.

Methods: A review of the medical records identified 12 men (mean age 35.8 years) who had undergone anastomotic urethroplasty for recurrent obliterated posterior stricture. Read More

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http://dx.doi.org/10.4103/2319-4170.106136DOI Listing
May 2013
3 Reads

Computed tomography-based navigation-assisted pedicle screw insertion for thoracic and lumbar spine fractures.

Chang Gung Med J 2012 Jul-Aug;35(4):332-8

Division of Spine, Department of Orthopaedic Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Incorrect placement of pedicle screws may lead to neurovascular injury, so the position is important for the reduction of spinal fractures. CT-based image-guided surgery has been promoted as a means to theoretically improve the accuracy of pedicle screw placement. Patients who underwent CT-based navigation-assisted pedicle screw fixation for thoracic or lumbar fractures were reviewed to evaluate the accuracy of pedicle screw placement for spinal fracture cases. Read More

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http://dx.doi.org/10.4103/2319-4170.106137DOI Listing
May 2013
10 Reads

Correlations between sexual dysfunction, depression, anxiety, and somatic symptoms among patients with major depressive disorder.

Chang Gung Med J 2012 Jul-Aug;35(4):323-31

Department of Psychiatry, Chang-Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: The purpose of this study was to investigate the degree of correlation between sexual dysfunction and depression, anxiety, and somatic symptoms among patients with major depressive disorder (MDD) and to identify the dimension most predictive of sexual dysfunction.

Methods: One-hundred and thirty-five outpatients with MDD were enrolled and were treated with open-label venlafaxine 75 mg daily for one month. The Arizona Sexual Experience Scale-Chinese Version (ASEX-CV), Depression and Somatic Symptoms Scale (DSSS), Hamilton Depression Rating Scale, and Hospital Anxiety and Depression Scale (HADS) were administered at baseline and at one-month follow-up and the improvement percentage (IP) of each scale posttreatment was calculated. Read More

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http://dx.doi.org/10.4103/2319-4170.106138DOI Listing
May 2013
2 Reads

High-fat diet aggravates islet beta-cell toxicity in mice treated with clozapine.

Chang Gung Med J 2012 Jul-Aug;35(4):318-22

Division of Endocrinology and Metabolism, Department of Internal Medicine, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Clozapine, an atypical antipsychotic drug, induces derangements in glucose homeostasis in certain patients. This study investigated the mechanisms of clozapine-induced beta-cell toxicity.

Methods: Fifty-two healthy C57BL/6 male mice were randomized into 4 groups to study the effects of clozapine (group C, D) and a high-fat diet (group B, D). Read More

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http://dx.doi.org/10.4103/2319-4170.106139DOI Listing
May 2013
8 Reads

Correlation of anaplastic lymphoma kinase overexpression and the EML4-ALK fusion gene in non-small cell lung cancer by immunohistochemical study.

Chang Gung Med J 2012 Jul-Aug;35(4):309-17

Department of Pathology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Recently the echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) fusion gene with transforming activity was identified in non-small cell lung cancer (NSCLC). In addition, NSCLC patients with the EML4-ALK fusion gene had a dramatic response and longer progression free survival after ALK inhibitor treatment than those without this fusion gene. However, the incidence and clinical and molecular characteristics of the EML4-ALK fusion gene in NSCLC patients of Taiwan are still unclear. Read More

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http://dx.doi.org/10.4103/2319-4170.106140DOI Listing
May 2013
9 Reads

Human papillomavirus research on the prevention, diagnosis, and prognosis of cervical cancer in Taiwan.

Chang Gung Med J 2012 Jul-Aug;35(4):297-308

Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Cervical cancer is third in incidence and fourth in mortality among cancers of women worldwide. Epidemiological studies have shown that human papillomavirus (HPV) is necessary, if not sufficient, to cause nearly 100% of cervical cancers. HPV testing is useful in primary screening for cervical neoplasms. Read More

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http://dx.doi.org/10.4103/2319-4170.106141DOI Listing
May 2013
3 Reads

Hepatoid microcarcinoma of the pancreas: a case report and review of the literature.

Chang Gung Med J 2012 May-Jun;35(3):285-91

Department of Pathology, Division of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Hepatoid differentiation in pancreatic carcinoma is a rare phenomenon. It occurs either as a pure form or as a component with other subtypes. Herein, we report a 52-year-old man with an ampullary large cell neuroendocrine carcinoma presenting with obstructive jaundice for 2 months. Read More

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http://dx.doi.org/10.4103/2319-4170.106142DOI Listing
November 2012
22 Reads

Variant origins of arteries in the carotid triangle - a case report.

Chang Gung Med J 2012 May-Jun;35(3):281-4

Department of Anatomy, Centre for Basic Sciences, Kasturba Medical College, Manipal University, Bejai, Mangalore, Karnataka, India.

The left superior laryngeal artery was observed arising from the external carotid artery instead of the superior thyroid artery in the cadaver of an approximately 70 year-old Asian man. In addition, on the same side, the superior thyroid artery arose from the common carotid artery 2 cm before the bifurcation instead of its usual origin from the external carotid artery. From the external carotid artery, the lingual and facial arteries arose from the common linguofacial trunk. Read More

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http://dx.doi.org/10.4103/2319-4170.106143DOI Listing
November 2012
3 Reads

Acute clinical deterioration of posterior fossa epidural hematoma: clinical features, risk factors and outcome.

Chang Gung Med J 2012 May-Jun;35(3):271-80

Department of Neurosurgery, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

Background: This study aimed to present experience in treating patients with posterior fossa epidural hematoma (PFEDH) and to discuss the risk factors, clinical features, and outcome in PFEDH patients with acute clinical deterioration (ACD).

Methods: Twenty-seven patients with PFEDH initially treated conservatively were evaluated. A comparison was made between patients with and without ACD during hospitalization. Read More

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http://dx.doi.org/10.4103/2319-4170.106144DOI Listing
November 2012
11 Reads

Classification and analysis of pathology of the long head of the biceps tendon in complete rotator cuff tears.

Chang Gung Med J 2012 May-Jun;35(3):263-70

Department of Orthopaedic Surgery, Chang Gung Memorial Hospital at Keelung, Taiwan.

Background: Pathology of the long head of the biceps tendon (LHB) is commonly associated with rotator cuff tears (RCTs). Superior labral anterior-posterior (SLAP) lesions can also occur with RCTs. The purpose of this study was to include SLAP lesions as part of LHB pathology in surgical cases of RCT and define the role of SLAP lesions in RCTs. Read More

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http://memo.cgu.edu.tw/cgmj/3503/350308.pdf
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http://dx.doi.org/10.4103/2319-4170.106145DOI Listing
November 2012
75 Reads

Comparison of central corneal thickness measurements by ultrasonic pachymetry, Orbscan II, and SP3000P in eyes with glaucoma or glaucoma suspect.

Chang Gung Med J 2012 May-Jun;35(3):255-62

Department of Ophthalmology, Kaohsiung Chang Gung Memorial Hospital, Taiwan.

Background: Intraocular pressure (IOP) measurements are affected by the central cornea thickness (CCT). The conventional method for CCT measurement is ultrasonic pachymetry. However, noncontact procedures lower the risk of infection and corneal damage. Read More

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http://dx.doi.org/10.4103/2319-4170.106146DOI Listing
November 2012
3 Reads

Adjuvant and salvage radiotherapy for urothelial cell carcinoma of the upper urinary tract: experience in a single institution.

Chang Gung Med J 2012 May-Jun;35(3):247-54

Department of Radiation Oncology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.

Background: To investigate the role of radiotherapy (RT) for upper urinary tract urothelial cell carcinoma (UTUC) after surgery.

Methods: Between July 1997 and February 2007, 40 patients who had undergone radical surgery and RT were selected. Twenty patients received RT as adjuvant treatment for advanced disease (PORT). Read More

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http://dx.doi.org/10.4103/2319-4170.106147DOI Listing
November 2012
12 Reads

Clinical utility of histological examination of gastric ulcer margin to diagnose Helicobacter pylori infection.

Chang Gung Med J 2012 May-Jun;35(3):240-6

Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: To investigate the effectiveness of histological examination of ulcer margins (HEUM) in detecting Helicobacter pylori (H. pylori) infection in patients with non-bleeding gastric ulcers (GUs).

Methods: A retrospective study included 284 patients with GU undergoing concomitant HEUM and rapid urease test (RUT) to detect H. Read More

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http://dx.doi.org/10.4103/2319-4170.106148DOI Listing
November 2012
11 Reads

Antiviral activity of liquorice powder extract against varicella zoster virus isolated from Egyptian patients.

Chang Gung Med J 2012 May-Jun;35(3):231-9

Holding Company for Biological Products and Vaccines, Cairo, Egypt.

Background: Varicella-zoster virus (VZV) is the etiologic agent of two diseases, varicella (chicken pox) and zoster (shingles). Varicella is a self- limited infection, while zoster is mainly a disease of adults. The present study was conducted to isolate VZV from clinically diagnosed children using cell cultures and compare the activity of liquorice powder extract, an alternative herbal antiviral agent, with acyclovir and interferon alpha 2a (IFN-α2a) against the isolated virus. Read More

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http://dx.doi.org/10.4103/2319-4170.106149DOI Listing
November 2012
42 Reads

Optimizing aesthetic and functional outcomes at donor sites.

Chang Gung Med J 2012 May-Jun;35(3):219-30

Department of Plastic Surgery, E-Da Hospital, Kaohsiung, Taiwan.

In recent years, there has been increasing interest by reconstructive surgeons in improving the aesthetic and functional outcomes of donor sites. As the success rate of free tissue transfers has exceeded more than 95% in most microsurgical centers, more emphasis can be shifted to the donor site. However, morbidities of donor sites can occur not only in free tissue transfers, but in locoregional flaps as well. Read More

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http://memo.cgu.edu.tw/cgmj/3503/350303.pdf
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http://dx.doi.org/10.4103/2319-4170.106150DOI Listing
November 2012
4 Reads

Amyloid plaque imaging from IMPY/SPECT to AV-45/PET.

Chang Gung Med J 2012 May-Jun;35(3):211-8

Department of Medical Imaging and Radiological Sciences, College of Medicine, Chang Gung University, Taoyuan, Taiwan.

The formation and deposition of β-amyloid (Aβ) plaques are the earliest pathological changes in Alzheimer's disease (AD). Molecular imaging of Aβ plaques could serve as a surrogate marker in early diagnosis and neuropathogenesis studies of AD. Several radionuclide labeled ligands have recently been developed for noninvasive visualization of Aβ plaques in the brains of AD patients using single photon emission computed tomography or positron emission tomography (PET). Read More

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http://dx.doi.org/10.4103/2319-4170.106151DOI Listing
November 2012
3 Reads

Phosphodiesterase 4 and its inhibitors in inflammatory diseases.

Chang Gung Med J 2012 May-Jun;35(3):197-210

Department of Life Sciences, National Central University, Jhongli, Taoyuan, Taiwan.

Type 4 cyclic nucleotide phosphodiesterases (PDE4) are a family of low km 3',5'-cyclic adenosine monophosphate (cAMP)-specific phosphodiesterases including at least 20 isozymes encoded by four genes (PDE4A, PDE4B, PDE4C, and PDE4D) in mammals. Each PDE4 gene plays a special, nonredundant role in the control of cell function even though the four subfamilies share the highly conserved catalytic domain and upstream conserved region (UCR) 1 and UCR2 motifs of the regulatory domain. By their wide tissue distribution as well as differential expression and regulation among various cell types, PDE4s are viewed as critical regulators of intracellular cAMP levels, cAMP signaling, and signal compartmentalization. Read More

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http://dx.doi.org/10.4103/2319-4170.106152DOI Listing
November 2012
3 Reads

Surgical resection of centrally located large hepatocellular carcinoma.

Chang Gung Med J 2012 Mar-Apr;35(2):178-91

Division of Transplantation and Liver Surgery, Department of General Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Centrally located large hepatocellular carcinoma (HCC) is a difficult issue in surgery. These HCCs can be treated by hemi-/extended or central hepatectomies. The aim of this study was to analyze the results of hemi-/extended and central hepatectomies. Read More

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http://dx.doi.org/10.4103/2319-4170.106153DOI Listing
August 2012
8 Reads

Eccrine angiomatous hamartoma: a retrospective study of 15 cases.

Chang Gung Med J 2012 Mar-Apr;35(2):167-77

Department of Dermatology, Chang Gung Memorial Hospital at Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Eccrine angiomatous hamartoma (EAH) comprises a rare nevoid proliferation of normal eccrine glands and small blood vessels and occasionally other elements in the middle and deep dermis with variable clinical manifestations. Case series have rarely been published except for case reports and literature reviews. The aims of this article were to investigate the clinical and pathologic features of patients with EAH in Taiwan and to compare our results with the results of previous studies. Read More

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http://dx.doi.org/10.4103/2319-4170.106154DOI Listing
August 2012
1 Read

Pierce and push: a simplified method to facilitate laparoscopic myomectomy.

Chang Gung Med J 2012 Mar-Apr;35(2):160-6

Division of Gynecologic Endoscopy, Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: The aim of this study was to present our experience with a novel approach called the pierce and push (PP) method which uses a stainless steel centimeter probe instead of a 5 mm claw forceps to enucleate fibroids in a laparoscopic myomectomy (LM).

Methods: A retrospective chart review of 90 women with symptomatic uterine fibroids who underwent an LM was performed. Cases of LM with the PP method were compared with a matched control group of LM with a 5 mm claw forceps. Read More

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http://dx.doi.org/10.4103/2319-4170.106155DOI Listing
August 2012
12 Reads

Anthropometric study of the bicipital groove in Indians and its clinical implications.

Chang Gung Med J 2012 Mar-Apr;35(2):155-9

Department of Anatomy, Centre for Basic Sciences, Kasturba Medical College, Manipal University, Bejai, Mangalore, India.

Background: Since morphometric data on the upper end of the humerus from Indian anatomical samples are scarce, this study was undertaken with reference to orthopedic surgery. The aim was to determine the length, width and depth of the bicipital groove and to find the incidence of a supratubercular ridge of Meyer in an Indian population.

Methods: The study included 104 unpaired dry humeri (48 right side and 56 left) which belonged to the anatomy laboratory of our institution. Read More

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http://dx.doi.org/10.4103/2319-4170.106156DOI Listing
August 2012
4 Reads

Etiological analyses of marked neonatal hyperbilirubinemia in a single institution in Taiwan.

Chang Gung Med J 2012 Mar-Apr;35(2):148-54

Division of Neonatology, Department of Pediatrics, Chang Gung Memorial Hospital at Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Hyperbilirubinemia is a common disorder during the neonatal period. Severe neonatal hyperbilirubinemia (NH) carries a potential for permanent neurological impairment. The current study analyzed possible etiologies leading to NH. Read More

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http://dx.doi.org/10.4103/2319-4170.106157DOI Listing
August 2012
4 Reads

Extract of sporoderm-broken germinating spores of ganoderma lucidum activates human polymorphonuclear neutrophils via the P38 mitogen-activated protein kinase pathway.

Chang Gung Med J 2012 Mar-Apr;35(2):140-7

Department of Traditional Chinese Medicine, Chang Gung Memorial Hospital at Taoyuan, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Background: Ganoderma lucidum (G. lucidum) has been used in traditional Chinese medicine for thousands of years because of its immunomodulatory properties. It is believed that G. Read More

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http://dx.doi.org/10.4103/2319-4170.106158DOI Listing
August 2012
7 Reads

Ultrasound microbubble contrast agents for diagnostic and therapeutic applications: current status and future design.

Chang Gung Med J 2012 Mar-Apr;35(2):125-39

Department of Biomedical Engineering and Environmental Sciences, National Tsing Hua University, Hsinchu, Taiwan.

Ultrasound contrast agents are highly echogenic microbubbles with many unique properties. Microbubbles can basically improve the sensitivity of conventional ultrasound imaging to the microcirculation. The resonance of microbubbles in response to an incident ultrasound pulse results in nonlinear harmonic emission that serves as the signature of microbubbles in microbubble-specific imaging. Read More

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http://dx.doi.org/10.4103/2319-4170.106159DOI Listing
August 2012
14 Reads

Host factors in the replication of positive-strand RNA viruses.

Chang Gung Med J 2012 Mar-Apr;35(2):111-24

Department of Biomedical Sciences, Chang Gung University, Taoyuan, Taiwan.

Viruses are obligate, intracellular parasites that depend on host cells for successful propagation. Upon infection of host cells, positivestrand RNA viruses exploit and hijack cellular machinery and reprogram these cells into viral "factories" through various protein-protein, protein- RNA, and protein-lipid interactions. The molecular interplay between host factors and invading viruses is a continuous process throughout the entire viral life cycle and determines virus host range and viral pathogenesis, as well as driving viral evolution. Read More

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http://dx.doi.org/10.4103/2319-4170.106160DOI Listing
August 2012
4 Reads

Molecular cytogenetics: an indispensable tool for cancer diagnosis.

Chang Gung Med J 2012 Mar-Apr;35(2):96-110

Division of Haematology, Department of Pathology, Queen Mary Hospital, University of Hong Kong, Hong Kong.

Cytogenetic aberrations may escape detection or recognition in traditional karyotyping. The past decade has seen an explosion of methodological advances in molecular cytogenetics technology. These cytogenetics techniques add color to the black and white world of conventional banding. Read More

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http://dx.doi.org/10.4103/2319-4170.106161DOI Listing
August 2012
6 Reads

The 2011 nobel prize in physiology or medicine.

Chang Gung Med J 2012 Mar-Apr;35(2):93-5

Department of Microbiology and Immunology; Graduate Institute of Biomedical Sciences, College of Medicine, Chang Gung University.

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http://dx.doi.org/10.4103/2319-4170.106162DOI Listing
August 2012
6 Reads

Tumor lysis syndrome in patients with light chain multiple myeloma: report of two cases.

Chang Gung Med J 2011 ;34(6 Suppl):70-5

Division of Hematology-Oncology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Tumor lysis syndrome (TLS) is a severe life-threatening complication which typically occurs in highly proliferative malignancies, such as Burkitt's lymphoma, acute leukemia or germ cell tumors. Although TLS is unusual in multiple myeloma, it should not be overlooked as it is associated with significant morbidity. In recent years, emerging new agents such as thalidomide and bortezomib have been found to be highly effective in the treatment of multiple myeloma. Read More

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August 2012
3 Reads

Bilateral metachronous osteosarcoma of the mandibular body: a case report.

Chang Gung Med J 2011 ;34(6 Suppl):66-9

Department of Oral and Maxillofacial Surgery Dental School, Mashhad University of Medical Sciences, Mashhad, Iran.

Osteosarcoma of the jaw (JOS) is a rare phenomenon constituting 5% to 13% of all cases of osteosarcoma (OS). JOS has histological features similar to OS, but the biological behavior is different. The chief complaint of patients with long bone OS is pain, whereas patients with JOS usually have painless swelling as the first sign. Read More

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August 2012
6 Reads

Supernumerary peronei in the leg musculature- utility for reconstruction.

Chang Gung Med J 2011 ;34(6 Suppl):62-5

Department of Anatomy, Vardhaman Mahavir Medical College & Safdarjung Hospital, New Delhi, India.

Muscular variations in the lower extremity are frequently encountered when performing cadaveric dissections. The utility of supernumerary muscles assumes importance in reparative foot surgery. The purpose of the current case study is to report the unilateral presence of double peroneal muscles in the evertors of the foot. Read More

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August 2012
12 Reads

A clinically-occult gastrointestinal stromal tumor in a Meckel's diverticulum presenting as hollow organ perforation.

Chang Gung Med J 2011 ;34(6 Suppl):56-61

Department of Anatomical Pathology, Far Eastern Memorial Hospital, Taipei, Taiwan.

Meckel's diverticulum is the most common congenital anomaly of the gastrointestinal tract. However, a neoplasm is a rare complication of Meckel's diverticulum. We report a case of a ruptured gastrointestinal stromal tumor (GIST) in a Meckel's diverticulum, presenting as hollow organ perforation, in a 76 year-old woman. Read More

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August 2012
14 Reads

Spontaneous splenic rupture with hematoma in a patient with brucellosis.

Chang Gung Med J 2011 ;34(6 Suppl):52-5

Department of Infectious Disease and Clinical Microbiology, School of Medicine, Afyon Kocatepe University, Turkey.

Brucellosis is one of the most common zoonotic diseases worldwide with a variable frequency in European countries. Brucellosis is usually transmitted after direct contact with or consumption of dairy products from an infected animal. Initially, our patient, a 65 year-old man, had nonspecific manifestations of fever, malaise, headache, anorexia and arthralgia which are the classic symptoms of this disease. Read More

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August 2012
24 Reads

Cisplatin-induced acute hyponatremia leading to a seizure and coma: a case report.

Chang Gung Med J 2011 ;34(6 Suppl):48-51

Clinical Pharmacy Division, Department of Pharmacy, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

We report a rare case of cisplatin-induced acute hyponatremia leading to a seizure and coma. A 66-year-old woman with breast cancer received adjuvant chemotherapy with docetaxel and cisplatin. She had no nausea, vomiting, or diarrhea during or after chemotherapy administration. Read More

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August 2012
14 Reads

Y-shaped colonic duplication: report of a case and literature review.

Chang Gung Med J 2011 ;34(6 Suppl):43-7

Division of Colorectal Surgery, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Colonic duplication is a very rare congenital anomaly that is usually detected in infancy and early childhood. In the English literature, 6 cases of Y-shaped colonic duplication have been reported since 1953. We conducted a review of the reported cases, and we present a new case of a Y-shaped duplication of the sigmoid colon manifesting as long-term abdominal pain and constipation. Read More

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August 2012
10 Reads

High origin of an ulnar artery--development and surgical significance.

Chang Gung Med J 2011 ;34(6 Suppl):39-42

Department of Anatomy, Rajiv Gandhi Institute of Medical Sciences, Adilabad, Andhra Pradesh, India.

Variations in the main arteries of the upper limb are common and these anomalies can be of substantial interest to orthopedic surgeons, plastic surgeons, radiologists and anatomists. We present here a case of a high origin of the ulnar artery from the brachial artery found during anatomical dissection of a right upper limb of a 50-year-old man. This superficial ulnar artery, after running over the bicipital aponeurosis in the cubital fossa superficial to the flexor muscles in the forearm terminated as the superficial palmar arch in the hand. Read More

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August 2012
6 Reads

Unusually high alanine aminotransferase to aspartate aminotransferase ratio in a patient with cyproterone-induced icteric hepatitis.

Chang Gung Med J 2011 ;34(6 Suppl):34-8

Division of Hepatology, Department of Gastroenterology and Hepatology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

A 70-year-old man with prostatic adenocarcinoma received cyproterone acetate 200 mg per day. Three months later, mild fatigue and anorexia with elevation of the alanine aminotransferase (ALT) level to 1311 U/L, total bilirubin level to 14 mg/dL and prothrombin time of 15/11.9 seconds developed. Read More

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August 2012
13 Reads

Anesthetic management of a repeat cesarean section in a parturient with severe peripartum cardiomyopathy requiring ECMO in a previous pregnancy: a case report.

Chang Gung Med J 2011 ;34(6 Suppl):28-33

Department of Anesthesiology, Chang Gung Memorial Hospital at Linkou, Chang Gung University College of Medicine, Taoyuan, Taiwan.

The number of pregnant women with cardiac disease is increasing with improvements in technology. In addition, more people are part of the national health insurance plan. However, there are few reports concerning the best method for anesthesia and mode of delivery in these high-risk patients. Read More

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August 2012
3 Reads

Unusual branching pattern of the external carotid artery in a cadaver.

Authors:
T Ramesh Rao

Chang Gung Med J 2011 ;34(6 Suppl):24-7

Department of Anatomy and Cell Biology Histology, American University of Antigua - Manipal Campus, Kasturba Medical College International Center, Manipal University, Manipal, Karnataka, India.

With the increasing use of invasive diagnostic and interventional procedures in cardiovascular disease, it is important to document and understand the types and frequencies of vascular variations. A sound knowledge of neurovascular variations is important for surgeons who remove cervical lymph nodes, for anesthesiologists, and for vascular surgeons. The external carotid arterial system is a complex vascular system which nourishes the terminal areas of the head, face and neck. Read More

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August 2012
2 Reads

Acute pulmonary embolism in a patient with hypereosinophilia and psoriasis.

Chang Gung Med J 2011 ;34(6 Suppl):17-23

Department of Dermatology, Chang Gung Memorial Hospital at Taipei, Chang Gung University College of Medicine, Taoyuan, Taiwan.

Peripheral blood hypereosinophilia reflects various underlying disorders. However, its thromboembolic consequences are not often highlighted. We report a case of acute pulmonary embolism in a 42 year-old male prisoner hospitalized for erythrodermic psoriasis who presented with generalized edema and shortness of breath. Read More

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August 2012
10 Reads

Slipped upper femoral epiphysis: a case of missed diagnosis.

Chang Gung Med J 2011 ;34(6 Suppl):13-6

Department of Orthopaedics and Traumatology, Faculty of Medicine, Universiti Kebangsaan Malaysia Medical Centre, Kuala Lumpur, Malaysia.

A slipped upper femoral epiphysis (SUFE) is a known hip disorder in adolescents in which the proximal femoral epiphysis slips and displaces relative to the metaphysis. We report an obese 12-year-old boy who presented with acute pain in the left hip after a fall. He was otherwise healthy with no prior joint pain. Read More

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August 2012
1 Read