617 results match your criteria Chalazion

Novel Meibomian Gland and Tarsal Conjunctival Changes Associated with Trastuzumab, Pertuzumab, and Anastrozole Treatment for Metastatic HER2 Positive Breast Cancer: A Case Report and Literature Review.

Case Rep Oncol 2022 May-Aug;15(2):486-493. Epub 2022 May 5.

Department of Internal Medicine and Hematology, Semmelweis University of Medicine, Budapest, Hungary.

The aim of the study was to report a case of severe meibomian gland dysfunction (MGD) and conjunctival changes associated with trastuzumab, pertuzumab, and anastrozole therapy in a HER-2 positive breast cancer patient. A 57-year-old white woman was treated with trastuzumab and pertuzumab biological and anastrozole endocrine therapy for metastatic breast cancer for several months. She suffered from intense eye pain and foreign body sensation. Read More

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Clinical Report: Correlation of Serum Vitamins and Chalazion.

Optom Vis Sci 2022 Jun 25;99(6):540-543. Epub 2022 Feb 25.

Department of Ophthalmology, Children's Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.

Significance: We demonstrate the clinical correlation between the vitamin A level with chalazion in East Chinese children. Vitamin A deficiency is likely to be a potential cause of childhood chalazion.

Purpose: Chalazion is the most common lid inflammatory lesion of the eyelid, which can be caused by retention of tarsal gland secretions. Read More

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Unique orbital biphenotypic tumour with neuroendocrine and sebaceous carcinoma features.

Orbit 2022 May 29:1-4. Epub 2022 May 29.

Department of Ophthalmology, Indiana University School of Medicine, Indianapolis, Indiana, USA.

A 60-year-old female presented with a large, left upper eyelid mass that had rapidly expanded in the 3 months prior to presentation. She had a presumed chalazion excised from the same area 1.5 years ago, but no pathology was investigated. Read More

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Clinical clues to identify patients with ocular rosacea - a Germany-wide epidemiologic analysis.

Int J Dermatol 2022 Jul 17;61(7):880-885. Epub 2022 May 17.

Department of Dermatology and Allergy, University Hospital of Munich (LMU), Munich, Germany.

Background And Objectives: Ocular rosacea is a special manifestation of rosacea with unknown etiology. Eye involvement in rosacea patients is surprisingly common; however, it is often underdiagnosed, resulting in inappropriate treatment. We aimed to provide an updated epidemiologic perspective on ocular rosacea in Germany to improve patient care. Read More

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Corneal Epithelial Remodeling as a Cause of Chalazion-Induced Hypermetropia.

Cornea 2022 Jun 19;41(6):785-788. Epub 2021 Oct 19.

Department of Ophthalmology, Mater Misericordiae Ltd, South Brisbane, QLD, Australia; and.

Purpose: The importance of the corneal epithelium and its role in influencing the refractive state of the eye is well established, as is the association between periocular mass lesions, such as chalazia, and changes in corneal refractive status. This case report provides new evidence linking these 2 phenomena.

Methods And Results: A 74-year-old man presented with gradual onset of blurred vision in his right eye. Read More

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Ophthalmology emergency department visits in a Brazilian tertiary hospital over the last 11 years: data analysis.

Arq Bras Oftalmol 2022 May 9. Epub 2022 May 9.

Department of Ophthalmology, Escola Paulista de Medicina, Universidade Federal de São Paulo, São Paulo, SP, Brazil.

Purpose: This study aimed to describe the visits profile to Hospital São Paulo's ophthalmology emergency department, a 24-hour public open-access tertiary-care service in São Paulo, Brazil, that belongs to Federal University of São Paulo, over the last 11 years.

Methods: A cross-sectional retrospective study was conducted, including all patients (n=634,726) admitted to the ophthalmology emergency department of Hospital São Paulo between January 2009 and December 2019.

Results: From 2009 to 2019, the number of patients' presentations increased to 39. Read More

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Global improvement in meibomian glands after chalazion surgery demonstrated by meibography.

Int Ophthalmol 2022 Apr 12. Epub 2022 Apr 12.

Ophthalmology Department, Baruch Padeh Medical Center, Dov Hoz 0., 15208, Poriya, Israel.

Purpose: To evaluate the use of meibography as an objective measure of the effects of incision & curettage (I&C) chalazion surgery on meibomian gland loss and morphology as well as dry eye syndrome.

Methods: This prospective, interventional clinical study included adult patients with a primary chalazion which persisted despite conservative treatment. All patients underwent I&C surgery. Read More

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Statin Use Is Associated With a Lower Risk of Blepharitis: A Population-Based Study.

Front Med (Lausanne) 2022 15;9:820119. Epub 2022 Mar 15.

Department of Ophthalmology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan.

Background: Blepharitis is a common eye disorder that may be overlooked by patients and clinical practitioners. The symptoms of blepharitis often manifest as irritation, a burning sensation, grittiness, and itchiness and may decrease visual acuity if not treated promptly. Meibomian gland dysfunction (MGD), a common cause of blepharitis, is believed to be associated with increased inflammatory marker levels that may disrupt the composition of lipids produced by the sebaceous glands in the eyelids and ultimately cause tear film instability. Read More

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Tele-ophthalmology as an aid tool for primary care physicians in the IDF, during the Covid-19 lockdown.

Int Ophthalmol 2022 Apr 2. Epub 2022 Apr 2.

Medical Corps, Israel Defense Forces, Tel Hashomer, Ramat Gan, Israel.

Purpose: To describe tele-ophthalmology consultations for primary-physicians in the IDF during the Covid-19 lockdown.

Methods: Retrospective cross-sectional study. Medical records of tele-ophthalmology consultations from March to June 2020 were reviewed. Read More

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Clinicopathological Features of 19 Eyelid Pilomatrixomas.

Ocul Oncol Pathol 2022 Feb 25;8(1):30-34. Epub 2021 Oct 25.

Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA.

Introduction: Pilomatrixoma is a relatively rare, benign tumor arising from the hair root matrix. It is found frequently on the head and neck, with most involving the eyebrow in the periocular region. In contrast, eyelid pilomatrixoma is less common, and often clinically misdiagnosed. Read More

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February 2022

Parent-provided photographs as an outcome measure for childhood chalazia.

J AAPOS 2022 04 18;26(2):60.e1-60.e5. Epub 2022 Mar 18.

Southern California College of Optometry at Marshall B. Ketchum University, Fullerton, California.

Purpose: To determine whether smartphone photographs of children's eyelids are reliable for diagnosing the presence of chalazia.

Methods: In this prospective cross-sectional study, 60 participants, 7 months to 16.5 years of age, at four sites were enrolled; all participants had a chalazion measuring at least 2 mm on at least one eyelid based on an in-person clinical examination by a pediatric eye care professional. Read More

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Efficacy of Intense Pulsed Light in the Treatment of Recurrent Chalaziosis.

Front Med (Lausanne) 2022 1;9:839908. Epub 2022 Mar 1.

Eye Center, Affiliated Second Hospital, School of Medicine, Zhejiang University, Hangzhou, China.

Purpose: High recurrence rate of chalaziosis and serious side effects of repeated surgical excision may help increase awareness of recurrent and refractory chalaziosis as a serious disorder affecting many aspects of life. This present study was aimed to investigate the efficacy and safety of intense pulse light (IPL) therapy and meibomian gland expression (MGX) in cases of recurrent chalaziosis after excision surgery.

Methods: Forty-two consecutive recurrent chalaziosis cases (35 patients) treated with IPL-MGX were enrolled. Read More

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Efficacy of Care and Antibiotic Use for Chalazia and Hordeola.

Eye Contact Lens 2022 Apr;48(4):162-168

School of Medicine (A.F.A., L.T., A.W.K.), University of California San Francisco, San Francisco, CA; Department of Ophthalmology (D.C.A., O.O.I., L.W., R.C.K., B.J.W., S.R.G., M.R.V.), University of California San Francisco, San Francisco, CA.

Objectives: To evaluate whether use of an antibiotic improves the efficacy of care for a chalazion or hordeolum.

Methods: A cross-sectional retrospective review was performed. All patients treated for a newly diagnosed chalazion or hordeolum at the University of California, San Francisco from 2012 to 2018 were identified. Read More

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The association of demodex infestation with pediatric chalazia.

BMC Ophthalmol 2022 Mar 16;22(1):124. Epub 2022 Mar 16.

Department of Ophthalmology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510282, Guangdong Province, China.

Purpose: This study aimed to investigate the association of Demodex infestation with pediatric chalazia.

Methods: In a prospective study, 446 children with chalazia and 50 children with non-inflammatory eye disease (controls) who underwent surgical treatment were enrolled from December 2018 to December 2019. Patient ages ranged from 7 months to 13 years old. Read More

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Infestation in Meibomian Gland Dysfunction Related Dry Eye Patients.

Front Med (Lausanne) 2022 24;9:833778. Epub 2022 Feb 24.

Beijing Tongren Eye Center, Beijing Tongren Hospital, Beijing Institute of Ophthalmology, Capital Medical University, Beijing, China.

Objective: To report the influence of infestation in patients with meibomian gland dysfunction (MGD) related dry eye and the associations of the infestation with MGD related dry eye.

Methods: Eyelashes (three from the upper eyelid and three from the lower eyelid) from 119 eyes of 119 patients diagnosed with MGD related dry eye were examined under a light microscope. There were 68 eyes of 68 patients with MGD related dry eye and infestation ( positive group) and 51 eyes of 51 patients without infestation ( negative group). Read More

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February 2022

Epidemiologic Differences and Management of Eyelid Lesions in the Pediatric Population.

J Pediatr Ophthalmol Strabismus 2022 Mar 11:1-5. Epub 2022 Mar 11.

Purpose: To report the relative incidence of excised pediatric eyelid lesions and describe the correlation between the clinical and pathology diagnosis.

Methods: This was a retrospective analysis of 137 consecutive pathology-confirmed eyelid lesions excised at a U.S. Read More

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[Metastasis of a neuroendocrine tumor mimicking a chalazion].

Ophthalmologe 2022 Mar 8;119(3):220. Epub 2022 Mar 8.

Augenklinik, Universitätsklinikum Bonn, Bonn, Deutschland.

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Not just a chalazion-focal eyelid and orbital infection with Saksaenea vasiformis in an immunocompetent child.

J AAPOS 2022 04 31;26(2):86-89. Epub 2022 Jan 31.

Department of Ophthalmology, Royal Children's Hospital, Parkville, Victoria, Australia; Department of Paediatrics, University of Melbourne, Parkville, Victoria, Australia. Electronic address:

We present the case of a 2-year-old immunocompetent boy who presented with subacute right-sided orbital cellulitis due to Saksaenea vasiformis infection. Initial differential diagnoses included chalazion and localized soft tissue malignancy. There was no history of trauma. Read More

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On the knowledge of solitary juvenile xanthogranuloma of the eyelid: a case series and literature review.

Graefes Arch Clin Exp Ophthalmol 2022 Jul 27;260(7):2339-2345. Epub 2022 Jan 27.

State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, 510060, China.

Purpose: Solitary eyelid juvenile xanthogranuloma (JXG) is extremely rare, and there is limited literature on its clinical features and treatment outcomes. Here, we present a case series and comprehensive review of the literature on patients with isolated eyelid JXG.

Methods: We systematically extracted data from our institution's records of isolated eyelid JXG cases and conducted a search for additional cases from the literature utilising the PubMed, Wanfang, and Chinese National Knowledge Infrastructure (CNKI) databases. Read More

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Effectiveness of oral probiotics supplementation in the treatment of adult small chalazion.

Int J Ophthalmol 2022 18;15(1):40-44. Epub 2022 Jan 18.

Department of Medicine and Health Sciences, "V. Tiberio", University of Molise, Campobasso, Molise 86100, Italy.

Aim: To define the possible beneficial impact of probiotics oral supplementation on patients affected by chalazion.

Methods: Prospective comparative pilot study on 20 adults suffering from chalazion randomly divided into two groups. The first group (=10) received conservative treatment with lid hygiene, warm compression, and dexamethasone/tobramycin ointment for at least 20d. Read More

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January 2022

The Effect of Chalazion Excision on Corneal Aberrometric and Densitometric Values.

Beyoglu Eye J 2021 27;6(3):191-199. Epub 2021 Sep 27.

Department of Ophthalmology, University of Health Sciences Gazi Yasargil Training and Research Hospital, Diyarbakir, Turkey.

Objectives: The aim of this study was to investigate the effect of chalazion excision on corneal aberrations and corneal densitometry.

Methods: Thirty-six patients with a chalazion in 1 eyelid and 40 healthy subjects were included in the study. Corneal aberration parameters of total root mean square (RMS), RMS high-order aberration (HOA), horizontal trefoil, oblique trefoil, horizontal coma, vertical coma, and spherical aberration values were measured using Scheimpflug corneal topography (Pentacam HR; Oculus Optikgeräte GmbH, Wetzler, Germany). Read More

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September 2021

Reconsidering the pathogenesis of chalazion.

Ocul Surf 2022 04 24;24:31-33. Epub 2021 Dec 24.

Department of Frontier Medical Science and Technology for Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan.

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The spectrum and clinicopathological correlation of eyelid lesions: Twenty years' experience at a tertiary eye care center in South India.

Indian J Ophthalmol 2022 Jan;70(1):43-50

Orbit, Oculoplasty, Reconstructive and Aesthetic Services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

Purpose: : To study the epidemiological pattern and diagnostic accuracy of histopathologically proven eyelid lesions over a period of two decades.

Methods: : A retrospective study of all histopathologically proven eyelid lesions from April 1996 to March 2016 was conducted. The lesions were broadly categorized as benign or malignant. Read More

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January 2022

Lichen simplex chronicus of the eyelid: A case report and literature review.

Am J Ophthalmol Case Rep 2021 Dec 25;24:101237. Epub 2021 Nov 25.

Department of Ophthalmology and Visual Science, State University of New York Upstate Medical University, 750 E Adams Street, NY, 13210, USA.

Purpose: To report a case of lichen simplex chronicus (LSC) of the eyelid and to perform a literature review on this topic.

Observations: A 59-year-old African American man presents with chronic and recalcitrant recurrent chalazion of both upper eyelids despite aggressive medical management. An incision and drainage procedure was performed along with biopsy of the eyelid, which was found to be consistent with LSC. Read More

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December 2021

The prevalence of various eyelid skin lesions in a single-centre observation study.

Postepy Dermatol Alergol 2021 Oct 8;38(5):804-807. Epub 2020 Jun 8.

Ocular Oncology Service, Department of Ophthalmology, Poznan University of Medical Sciences, Poznan, Poland.

Introduction: The role of the eyelids is to protect and moisturise the eye. Despite its small relative surface area, 5-10% of skin cancers originate in the eyelids.

Aim: To assess the prevalence of different types of skin lesions in the area of eyelids based on retrospective histopathology data from a tertiary centre. Read More

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October 2021


Cesk Slov Oftalmol 2021 ;77(5):257-263

Aim: To present rare form of lids amyloidosis, in the context with literature and remind a Czech professor Vrabec, F., MD, an important pan-European ocular histologist.

Case Report: 37 years aged man was examined for eyelids mass on the department of ophthalmology of the Teaching Hospital Kralovske Vinohrady, Prague, Czech Republic in June 2018. Read More

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October 2021

Eyelid nodules in idiopathic facial aseptic granuloma.

Arch Soc Esp Oftalmol (Engl Ed) 2021 Oct 24;96(10):556-560. Epub 2021 Sep 24.

Departamento de Anatomía Patológica, Hospital Universitario Río Hortega, Valladolid, Spain.

Idiopathic facial aseptic granuloma (IFAG) is a recently described and rare condition. It is considered a form of infantile granulomatous rosacea. IFAG with facial and eyelid nodules is very rare. Read More

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October 2021

Ophthalmic Virtual Visit Utilization and Patient Satisfaction During the COVID-19 Pandemic.

Telemed J E Health 2022 Jun 4;28(6):798-805. Epub 2021 Oct 4.

Department of Ophthalmology and Weill Cornell Medicine, New York, New York, USA.

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TearCare for the Treatment of Meibomian Gland Dysfunction in Adult Patients With Dry Eye Disease: A Masked Randomized Controlled Trial.

Cornea 2022 Apr;41(4):417-426

Sight Sciences, Inc, Menlo Park, CA.

Purpose: The aim of this study was to demonstrate the safety and effectiveness of a single TearCare procedure compared with a single LipiFlow procedure in treatment of the dry eye disease associated with meibomian gland dysfunction.

Methods: In a multicenter, masked, randomized controlled trial, 135 subjects received a single TearCare (TC) treatment (n = 67) or a single LipiFlow (LF) treatment (n = 68) at baseline and were followed up for 1 month posttreatment. Tear film breakup time, meibomian gland function, and corneal and conjunctival staining scores were assessed as dry eye signs at baseline, 2 weeks, and 1 month; dry eye symptoms were assessed using the Ocular Surface Disease Index, Symptom Assessment in Dry Eye, and eye dryness questionnaires at baseline and 1 month. Read More

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Conjunctival Pyogenic Granuloma Masquerading as Malignant Melanoma.

Cureus 2021 Aug 9;13(8):e17029. Epub 2021 Aug 9.

Ophthalmic Plastic Surgery & Ocular Oncology, Advanced Eye Hospital & Institute, Mumbai, IND.

Pyogenic granuloma is a common, benign, vascular growth that often appears as a rapidly growing mass on mucus membrane-lined surfaces such as the conjunctiva. Conjunctival pyogenic granulomas are common following trauma, burst chalazion or ill-fitting prosthesis. Also known as 'lobular capillary hemangiomas', these lesions typically appear bright red, fleshy and pedunculated. Read More

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