58,709 results match your criteria Cesarean Delivery


Cesarean section scar in 3 T magnetic resonance imaging and ultrasound: image characteristics and comparison of the methods.

Arch Gynecol Obstet 2018 Dec 5. Epub 2018 Dec 5.

Department of Obstetrics, University of Leipzig, Liebigstrasse 20a, 04103, Leipzig, Germany.

Purpose: Uterine rupture during labor is a rare but life-threatening complication after previous cesarean section (CS). Prenatal risk is assessed using ultrasound thickness measurement of the lower uterine segment (LUS). Due to inhomogeneous study results, however, clinical obstetrics still lacks for standard protocols and reliable reference values. Read More

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December 2018
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ED of intrathecal ropivacaine for cesarean delivery with and without epidural volume extension with normal saline: a randomized controlled study.

Authors:
M Lv P Zhang Z Wang

J Pain Res 2018 8;11:2791-2796. Epub 2018 Nov 8.

Institute of Clinical Research, Jiaxing university, Jiaxing, China,

Background: It was reported that epidural volume extension could decrease the ED of intrathecal plain bupivacaine. In this study, we investigated the ED of intrathecal hyperbaric ropivacaine followed by epidural normal saline bolus for cesarean section.

Methods: Sixty parturients were allocated into two groups in this prospective study. Read More

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November 2018

Practice of emergency obstetric care signal functions and reasons for non-provision among health centers and hospitals in Lake and Western zones of Tanzania.

BMC Health Serv Res 2018 Dec 5;18(1):944. Epub 2018 Dec 5.

National Institute for Medical Research (NIMR)-Headquarters, PO Box 9356, Dar-es-Salaam, Tanzania.

Background: The Lake and Western Zones of Tanzania that encompass eight regions namely; Kagera, Geita, Simiyu, Shinyanga, Mwanza, Mara Tabora and Kigoma have consistently been reported with the poorest Maternal Newborn and Child Health (MNCH) indicators in the country. This study sought to establish the provision of Emergency Obstetric Care (EmOC) signal functions and reasons for the failure to do so among health centers and hospitals in the two zones.

Methods: All the 261 public and private hospitals and health centers providing Obstetric Care services in Lake and Western Zones were surveyed in 2014. Read More

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December 2018
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Laterally-positioned placenta in placenta previa.

J Matern Fetal Neonatal Med 2018 Dec 5:1-161. Epub 2018 Dec 5.

a Department of Obstetrics and Gynecology , Jichi Medical University , Shimotsuke , Tochigi , Japan.

Objectives: To clarify perinatal outcomes of patients with placenta previa (PP) with the placenta mainly positioned in the lateral uterine wall (lateral PP), thereby clinically characterizing this condition.

Study Design: The retrospective cohort study was performed involving patients with lateral PP between January 2006 and December 2016. The placental position was determined and classified by magnetic resonance imaging. Read More

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December 2018
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Using the Probability of Cesarean from a Validated Cesarean Prediction Calculator to Predict Labor Length and Morbidity.

Am J Perinatol 2018 Dec 3. Epub 2018 Dec 3.

Maternal and Child Health Research Center, Department of Obstetrics & Gynecology, University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania.

Objective:  To determine if increasing predicted risk of cesarean was associated with longer labor length and increased morbidity among women undergoing induction with an unfavorable cervix.

Study Design:  Using a publically available database, we evaluated whether a previously validated prediction model for cesarean delivery after induction was associated with labor length, maternal morbidity (third-/fourth-degree lacerations, endometritis, blood transfusion, wound infection, venous thromboembolism, hysterectomy, intensive care unit admission, and death), and neonatal morbidity (blood transfusion, encephalopathy, intraventricular hemorrhage, severe respiratory distress syndrome, necrotizing enterocolitis, and sepsis). Full-term (≥37 weeks) singleton gestations with intact membranes and an unfavorable cervix (Bishop score ≤6 and dilation ≤2 cm) undergoing induction of labor were included. Read More

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December 2018

Prophylactic negative pressure wound therapy at cesarean: Are we there yet?

Authors:
Methodius Tuuli

BJOG 2018 Dec 3. Epub 2018 Dec 3.

Indiana University School of Medicine, Obstetrics& Gynecology, 340 West 10th Street, Fairbanks Hall, Suite 6200, Indianapolis, IN 46202-3082,USA.

Prophylactic negative pressure wound therapy (NPWT) has emerged as a promising intervention in patients at high risk for surgical site infection (SSI). One such group is obese gravidae, a growing population worldwide who are at high risk for both cesarean delivery and SSI. Although the precise mechanism by which NPWT aids incisional wound healing is unclear, experimental evidence suggests that it reduces bacterial contamination, edema, and exudate, increases microvascular blood flow, promotes formation of granulation tissue and reduces lateral tensile and shear stress. Read More

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December 2018

Acute hypoglycemia during cesarean delivery in a patient with Type-1 diabetes mellitus.

Int J Obstet Anesth 2018 Nov 17. Epub 2018 Nov 17.

Department of Anaesthesiology, Nara Medical University, Kashihara, Nara, Japan.

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November 2018

Fetal Heart Rate Auscultation, 3rd edition.

Nurs Womens Health 2018 Dec;22(6):e1-e32

The use of intermittent auscultation (IA) for fetal surveillance during labor decreased with the introduction of electronic fetal monitoring (EFM). The increased use of EFM is associated with an increase in cesarean births. IA is an evidence-based method of fetal surveillance during labor for women with low risk pregnancies and considered one component of comprehensive efforts to reduce the primary cesarean rate and promote vaginal birth. Read More

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December 2018

Role of Corticosteroids in Reducing Respiratory Morbidity in Neonates Delivered by Elective Cesarean Section before 39 Weeks.

J Coll Physicians Surg Pak 2018 Dec;28(12):906-909

Department of Neonatology, Military Hospital, Rawalpindi, Pakistan.

Objective: To determine the effect of dexamethasone administration to women between 37 to 39 weeks of gestation on neonatal outcome in terms of respiratory morbidity and the need for NICU admission.

Study Design: An experimental study.

Place And Duration Of Study: Department of Obstetrics and Department of Neonatology, Military Hospital, Rawalpindi, Pakistan, from February to July 2017. Read More

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December 2018

Absorbable suture. Best aesthetic outcome in cesarian scar1.

Acta Cir Bras 2018 Nov;33(11):1027-1036

PhD, Associate Professor, Translational Surgery Post Graduate Program, Universidade Federal de São Paulo (UNIFESP), and Professional Masters in Sciences Applied to Health, UNIVÁS, Pouso Alegre-MG, Brazil. Interpretation and analysis of data, critical revision.

Purpose: To compare two suture threads, poliglecaprone 25 and nylon, used as intradermal suture for skin closure in women undergoing their first cesarean section.

Methods: This is a randomized clinical trial. A total of 60 women undergoing their first cesarean section were enrolled and prospectively assessed. Read More

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November 2018
3 Reads

Twin Pregnancy in Brazil: A Profile Analysis Exploring Population Information from the National Birth E-Registry on Live Births.

Biomed Res Int 2018 1;2018:9189648. Epub 2018 Nov 1.

Department of Obstetrics and Gynecology, University of Campinas School of Medicine, 101 Alexander Fleming Street, 13083-891 Campinas, Brazil.

Birth records as SINASC (Brazilian Live Birth Information System) are highlighted in uncommon conditions such as twin pregnancy whose prevalence rarely exceeds 2 to 3% of the total number of births. The objective of this study was to assess the prevalence of twin pregnancies in Brazil and their maternal and perinatal characteristics using data from the national birth e-Registry. All births in Brazil from 2011 to 2014 were assessed. Read More

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November 2018
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Prevalence and Associated Factors of Perinatal Asphyxia among Neonates in General Hospitals of Tigray, Ethiopia, 2018.

Biomed Res Int 2018 1;2018:5351010. Epub 2018 Nov 1.

Department of Midwifery, College of Medicine and Health Sciences, Adigrat University, Adigrat, Ethiopia.

Perinatal asphyxia is one of the most important causes of morbidity and mortality in neonates. Perinatal asphyxia occurs in association with maternal, fetal, and maternofetal factors. However, the magnitude and associated factors of perinatal asphyxia are not well studied in Tigray, Ethiopia. Read More

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November 2018
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Effectiveness of Trauma-Focused Psychological Therapies for Treating Post-traumatic Stress Disorder Symptoms in Women Following Childbirth: A Systematic Review and Meta-Analysis.

Front Psychiatry 2018 20;9:591. Epub 2018 Nov 20.

School of Psychology & Clinical Language Sciences, University of Reading, Reading, United Kingdom.

Approximately 3% of women in community samples develop posttraumatic stress disorder (PTSD) after childbirth. Higher prevalence rates are reported for high risk samples. Postpartum PTSD can adversely affect women's wellbeing, mother-infant relationships and child development. Read More

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November 2018

Prolonged operative time of repeat cesarean is a risk marker for post-operative maternal complications.

BMC Pregnancy Childbirth 2018 Dec 4;18(1):477. Epub 2018 Dec 4.

Department of Obstetrics and Gynecology, Shaare Zedek Medical Center, Hebrew University, Jerusalem, Israel.

Background: Repeat cesarean delivery (CD) accounts for approximately 15% of all annual deliveries in the US with an estimated 656,250 operations per year. We aimed to study whether prolonged operative time (OT; skin incision to closure) is a risk marker for post-operative maternal complications among women undergoing repeat CD.

Methods: We conducted a cross-sectional retrospective study in a single tertiary center including all women who underwent repeat CD but excluding those with cesarean hysterectomy. Read More

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December 2018

[Treatment of HIV in Pregnancy - Progress Over One Decade].

Z Geburtshilfe Neonatol 2018 Dec 4. Epub 2018 Dec 4.

Medizinische Klinik und Poliklinik I, Universitätsklinikum Bonn, Bonn.

Introduction: Worldwide, 37 million people are infected with HIV; more than 50% are women. Currently, MTCT (mother-to-child transmission) can be reduced to<1%. The intention of the present study was to analyze the development of (1) the course of pregnancy of HIV-infected women, (2) the mode of delivery and (3) the post-exposure prophylaxis of the newborn over the last decade. Read More

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December 2018
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Maternal/Perinatal Outcome in Women with Sickle Cell Disease: A Comparison of Two Time Periods.

South Med J 2018 Dec;111(12):742-745

From the Department of Obstetrics and Gynecology, University of Arkansas for Medical Sciences, Little Rock, the Department of Obstetrics and Gynecology of the University of Mississippi Medical Center, Jackson, and Department of Obstetrics and Gynecology, University of Kansas Medical Center, Kansas City.

Objective: To compare pregnancy outcomes in women with sickle cell disease from recent deliveries with a similar group delivered earlier.

Methods: During a 12-year period (2005-2016), data from pregnant women with hemoglobin SS or SC were collected from three university medical centers and compared with earlier studies (1979-2003) involving similar patients. The primary endpoints were maternal complications during pregnancy and newborn outcomes. Read More

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December 2018

Postpartum hemorrhage and blood transfusion among parturients with scarred uterus - the evidence is there.

Acta Obstet Gynecol Scand 2018 Dec 4. Epub 2018 Dec 4.

Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

We read the study by Pont et al. with great interest. They performed a retrospective population-based record linkage study evaluating the transfusion risk associated with intended vaginal birth after cesarean (VBAC) compared to elective repeat cesarean section (ERCS). Read More

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December 2018
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Childhood health and education outcomes following early term induction for large-for-gestational age: a population-based record linkage study.

Acta Obstet Gynecol Scand 2018 Dec 4. Epub 2018 Dec 4.

Clinical and Population Perinatal Health Research, Kolling Institute, Northern Sydney Local Health District, Sydney, NSW, Australia.

Introduction: There is debate about optimal management of pregnancies with a large-for-gestational age baby. A recent randomized controlled trial reported that early term induction of labor reduced cesarean section rates and infant morbidity. However, long term childhood outcomes have not been assessed. Read More

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December 2018
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Case of uterine rupture after multiple intrauterine operations and uterine artery embolization.

J Obstet Gynaecol Res 2018 Dec 3. Epub 2018 Dec 3.

Department of Obstetrics and Gynecology, Aso Iizuka Hospital, Iizuka, Fukuoka, Japan.

Uterine rupture is rare but may result in both maternal and fetal death. The factors involved in such deaths depend on each case, but uterine artery embolization (UAE), the common treatment for hemorrhage, is possibly one factor. UAE may be related to uterine rupture or placenta accreta, but few data exist regarding UAE and uterine rupture. Read More

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December 2018

Correlation of short-term variation and Doppler parameters with adverse perinatal outcome in low-risk fetuses at term.

Arch Gynecol Obstet 2018 Dec 3. Epub 2018 Dec 3.

Department of Obstetrics and Gynecology, Erlangen University Hospital, Universitätsstraße 21-23, 91054, Erlangen, Germany.

Objective: To evaluate the association of short-term variation (STV) and Doppler parameters with adverse perinatal outcome in low-risk fetuses at term.

Methods: This was a retrospective study of 1008 appropriate-for-gestational age (AGA) term fetuses. Doppler measurements [umbilical artery (UA), middle cerebral artery (MCA), and cerebroplacental ratio (CPR)] and computerized CTG (cCTG) with STV analysis were performed prior to active labor (≤ 4 cm cervical dilatation) within 72 h of delivery. Read More

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December 2018

A 10-year update: national survey questionnaire of obstetric anesthesia units in Israel.

Int J Obstet Anesth 2018 Nov 2. Epub 2018 Nov 2.

Department of Anesthesiology, Perioperative Medicine & Pain Treatment, Shaare Zedek Medical Center, Affiliated with the Hadassah-Hebrew University Medical School Ein-Kerem, Jerusalem, Israel.

Background: This nationwide survey was conducted to provide data about the obstetric anesthesia services in Israeli labor and delivery units in 2016.

Methods: Prospective survey questionnaire was emailed to obstetric anesthesia unit directors/chairperson of all 25 labor and delivery services units within the jurisdiction of the Israeli Ministry of Health.

Results: The response rate was 100%. Read More

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November 2018

Intracervical Foley catheter balloon versus dinoprostone insert for induction cervical ripening: A systematic review and meta-analysis of randomized controlled trials.

Medicine (Baltimore) 2018 Nov;97(48):e13251

Clinical Medicine College, Soochow University, Suzhou Jiangsu, China.

Background: Successful labor induction depends on the cervical status at the time of induction. Currently, both a Foley catheter and a dinoprostone insert are used for effective cervical ripening. This study compared the efficacy and safety of the intracervical Foley catheter and dinoprostone insert for cervical ripening to achieve successful labor induction. Read More

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November 2018

Bacterial Vaginosis: An insight into the prevalence, alternative regimen treatments and it's associated resistance patterns.

Microb Pathog 2018 Nov 28;127:21-30. Epub 2018 Nov 28.

Atta-Ur-Rahman School of Applied Bio-Sciences, Department of Healthcare Biotechnology, National University of Sciences and Technology, Islamabad, 44000, Pakistan. Electronic address:

Bacterial Vaginosis (BV) is a complex polymicrobial infection of vagina that shifts the paradigms of vaginal flora from lactobacilli to opportunistic pathogens. BV is catagorized by greyish white discharge, pH greater than 4.5. Read More

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November 2018
5 Reads

Azithromycin-based Extended-Spectrum Antibiotic Prophylaxis for Cesarean: Role of Placental Colonization with Genital Ureaplasmas and Mycoplasmas.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Center for Women's Reproductive Health, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  To explore whether the effect of azithromycin (AZI) on postcesarean infections varied by the presence/absence of genital mycoplasmataceae placental colonization.

Materials And Methods:  This was a single-center substudy of multicenter double-blind C/SOAP (Cesarean Section Optimal Antibiotic Prophylaxis) trial of women randomized to AZI or placebo (+cefazolin) antibiotic prophylaxis at cesarean. Chorioamnion/placenta specimens were tested for genital mycoplasmataceae colonization by polymerase chain reaction. Read More

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November 2018
3 Reads

Impact of Gestational Weight Gain on Trial of Labor after Cesarean Success.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Division of Maternal-Fetal Medicine, Department of Obstetrics, Gynecology, and Reproductive Sciences, University of California, San Francisco, San Francisco, California.

Objective:  Excessive gestational weight gain (GWG) has been associated with adverse pregnancy outcomes, including increased risk of cesarean delivery (CD). Data are limited on associations between GWG and outcomes in women undergoing trial of labor after cesarean (TOLAC). We aimed to investigate whether appropriate GWG impacts TOLAC outcomes. Read More

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November 2018

Placenta Accreta: A Spectrum of Predictable Risk, Diagnosis, and Morbidity.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Department of Obstetrics, Gynecology, and Reproductive Sciences, Yale School of Medicine, New Haven, Connecticut.

Objective:  Placenta accreta is a feared pathology, in part, because prenatal diagnosis is imperfect. It is not known whether clinical risk factors or sonographic features equally predict the entire graded pathological spectrum of placental overinvasion disease nor whether clinical outcomes differ along the spectrum.

Study Design:  We conducted a mixed methods retrospective study of a cohort of women screened sonographically for placenta accreta, cross-referenced against cases identified by pathological diagnosis ( = 416). Read More

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November 2018
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Early Pregnancy Hemoglobin A1C and Pregnancy Outcomes: A Population-Based Study.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Kaiser Permanente Washington Health Research Institute, Seattle, Washington.

Objectives:  Women with prediabetes are identified from screening for overt diabetes in early pregnancy, but the clinical significance of prediabetes in pregnancy is unclear. We examined whether prediabetes in early pregnancy was associated with risks of adverse outcomes.

Study Design:  We conducted a retrospective cohort study of pregnant women enrolled in Kaiser Permanente Washington from 2011 to 2014. Read More

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November 2018
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Risk Factors and Maternal Morbidity Associated with Unintentional Hysterotomy Extension at the Time of Cesarean Delivery.

Am J Perinatol 2018 Nov 30. Epub 2018 Nov 30.

Department of Obstetrics and Gynecology, Washington University School of Medicine in St. Louis, St. Louis, Missouri.

Objective:  Our aim was to estimate the incidence of unintentional hysterotomy extension at the time of cesarean delivery and to identify associated risk factors and maternal morbidity.

Study Design:  We conducted a secondary analysis of a randomized controlled trial evaluating chlorhexidine-alcohol versus iodine-alcohol for skin antisepsis in women undergoing cesarean delivery. We included patients with a low transverse hysterotomy. Read More

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November 2018
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Diabetes Mellitus and lower genital tract tears after vaginal birth: A cohort study.

Midwifery 2018 Nov 22;69:121-127. Epub 2018 Nov 22.

Department of Obstetrics and Gynaecology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, DK-8200, Denmark; Department of Clinical Medicine, Aarhus University, Incuba / Skejby Building 2 Palle Juul-Jensens Boulevard 82, Aarhus DK-8200, Denmark. Electronic address:

Introduction: Diabetes Mellitus in pregnancy is increasing. No existing studies have examined Diabetes Mellitus as the primary exposure for lower genital tract tears after vaginal birth. The objective was to study the association between Diabetes Mellitus (all types combined), Type 1 Diabetes Mellitus, Type 2 Diabetes Mellitus and Gestational Diabetes Mellitus and lower genital tract tears after vaginal birth. Read More

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November 2018

Use of a criteria-based audit to optimize uptake of cesarean delivery in a low-resource setting.

Int J Gynaecol Obstet 2018 Nov 30. Epub 2018 Nov 30.

Department of Women's and Children's Health, International Maternal and Child Health, Uppsala University, Uppsala, Sweden.

Objective: To evaluate the impact of criteria-based audit (CBA) of obstructed labor and fetal distress on cesarean delivery and perinatal outcomes.

Methods: A cross-sectional study was performed at a tertiary referral hospital in Tanzania. Data were collected before and after CBA (January 2013-November 2013 and July 2015-June 2016). Read More

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November 2018

Postpartum anticoagulation in women with mechanical heart valves.

Int J Womens Health 2018 25;10:663-670. Epub 2018 Oct 25.

Department of Obstetrics, Gynecology and Reproductive Sciences, Section of Maternal-Fetal Medicine, Yale University School of Medicine, New Haven, CT, USA,

Background: Women with mechanical heart valves (MHV) requiring anticoagulation (AC) are at high risk for hemorrhagic complications. Despite guidelines to manage antenatal and peripartum AC, there are few evidence-based recommendations to guide the initiation of postpartum AC. We reviewed our institutional experience of pregnant women with MHV to lay the groundwork for recommendations of immediate postpartum AC therapy. Read More

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October 2018
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Elective induction of labor: A prospective observational study.

PLoS One 2018 29;13(11):e0208098. Epub 2018 Nov 29.

Department of Obstetrics and Gynecology, St. Olav's Hospital, University Hospital of Trondheim, Trondheim, Norway.

The aim of the present study was to assess indications for induction and describe the characteristics and delivery outcome in medical compared to non-medical/elective inductions. During a three-month period, 1663 term inductions were registered in 24 delivery units in Norway. Inclusion criteria were singleton pregnancies with cephalic presentation at gestational age 37+0 and beyond. Read More

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November 2018

Ovarian reserve after uterine artery embolization in women with morbidly adherent placenta: A cohort study.

PLoS One 2018 29;13(11):e0208139. Epub 2018 Nov 29.

Department of Obstetrics and Gynecology, Sheba Medical Center, Tel-Hashomer, Israel.

Objective: To evaluate ovarian reserve in women after preservative cesarean delivery using uterine artery embolization due to morbidly adherent placenta.

Study Design: A historical cohort study including all women admitted to a single tertiary care center, with morbidly adherent placenta that had preservative cesarean delivery with bilateral uterine artery embolization. Inclusion criteria included gestational age >24 weeks, singleton pregnancy and placenta increta / percreta. Read More

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November 2018

Stillbirths in women with pre-gravid obesity.

J Perinat Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Obstetrics and Gynecology, Kaplan Medical Center, affiliated with the Hadassah-Hebrew University School of Medicine, Jerusalem, Rehovot, Israel.

Objective To determine the association between pre-gravid obesity and stillbirth. Methods A retrospective study of a population-based dataset of births at ≥34 weeks' gestation. We excluded fetal deaths due to lethal anomalies and intrapartum fetal deaths. Read More

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November 2018
1 Read

Lumbar epidural analgesia for labor in a parturient with a history of surgery for lumbar intradural ependymoma: Literature review and case presentation.

Surg Neurol Int 2018 23;9:211. Epub 2018 Oct 23.

Department of Anesthesiology, Advocate Illinois Masonic Medical Center, Chicago, Illinois, USA.

Background: Ependymomas represent 50-60% of all brain and central nervous system tumors. Previous lumbar spine surgery for resection of an ependymoma should not be considered a relative contraindication for the administration of epidural/subarachnoid anesthesia to patients in labor.

Case Description: A 34-year-old G1P0, who underwent resection of an L1-L3 intramedullary ependymoma 8 years previously, presented in active labor with residual left leg numbness and tingling. Read More

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October 2018

A headache-free reversible cerebral vasoconstriction syndrome (RCVS) with symptomatic brain stem ischemia at late pregnancy as a rare manifestation of RCVS resolved with termination of pregnancy by semi-urgent cesarean section.

Oxf Med Case Reports 2018 Dec 21;2018(12):omy101. Epub 2018 Nov 21.

Department of Neurosurgery, Uonuma Institute of Community Medicine, Niigata University Medical and Dental Hospital, Minami-Uonuma, Niigata, Japan.

A 32-year-old pregnant woman in her 39th week of pregnancy presented at the emergency room complaining of sudden-onset dizziness with gaze disturbance and was admitted to our hospital. Her past medical history included hypertension, diabetes mellitus and infarction in the right medulla oblongata 18 months prior to this event. Magnetic resonance (MR) angiography showed multiple irregular stenosis of the intracranial arterial system. Read More

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December 2018
1 Read

The Physiological Variation in Plasma Presepsin Levels During the Early Neonatal Period.

Tohoku J Exp Med 2018 ;246(3):199-203

Department of Pediatrics, School of Medicine, University of Occupational and Environmental Health, Japan.

Neonatal sepsis continues to be a global problem with significant morbidity and mortality, because of the difficulty in predicting its onset with clinical symptoms alone. Thus, the presence of biomarkers is useful for the diagnosis of neonatal sepsis. Presepsin is a 13-kDa truncated form of soluble CD14 that is produced through proteolytic cleavage on activated monocytes. Read More

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January 2018

Cesarean Section Induces Microbiota-Regulated Immune Disturbances in C57BL/6 Mice.

J Immunol 2018 Nov 28. Epub 2018 Nov 28.

Department of Veterinary and Animal Sciences, Faculty of Health and Medical Sciences, University of Copenhagen, 1871 Frederiksberg C, Denmark.

Epidemiological studies have shown that children born by cesarean section (CS) are at higher risk of developing chronic inflammatory diseases, and it has been suggested that a skewed gut microbial colonization process early in life and altered priming of the immune system are causative. The aim of this study was to clarify whether impaired regulatory immunity in CS-delivered C57BL/6 mice is dependent on gut microbiota (GM) disturbances. The GM of conventionally bred mice born by CS differed clearly from mice born by vaginal delivery. Read More

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November 2018
3 Reads

Delivery mode and perinatal outcomes after diagnosis of oligohydramnios at term in China.

J Matern Fetal Neonatal Med 2018 Nov 28:1-181. Epub 2018 Nov 28.

b Department of Obstetrics and Gynecology , Brigham and Women's Hospital , Harvard Medical School , Boston , USA.

Objective: The purpose of this study is to assess the incidence of oligohydramnios at term and evaluate whether mode of delivery in patients with oligohydramnios influences perinatal outcomes in China.

Methods: A cross sectional survey of all deliveries in 39 hospitals in China from 1 January to 31 December, 2011 was evaluated for mode of delivery and perinatal outcomes in women with oligohydramnios compared to those without known oligohydramnios after excluding preterm births, polyhydramnios, and oligohydramnios secondary to premature rupture of membranes.

Results: Oligohydramnios complicated 3954 (4. Read More

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November 2018
1 Read

The role of supracervical hysterectomy in reducing blood products requirement in the management of placenta accreta: A case control study.

J Matern Fetal Neonatal Med 2018 Nov 28:1-151. Epub 2018 Nov 28.

a Department of Obstetrics and Gynecology , Hadassah , Hebrew University Medical Center , Jerusalem , Israel.

Objective: While surgical management is the treatment of choice for abnormally invasive placenta, the role of supracervical hysterectomy in this setting is not well established. We aimed to compare supracervical versus total cesarean hysterectomy as a surgical option for abnormally invasive placenta.

Methods: We carried out a 8-year retrospective case-control study. Read More

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November 2018

Blunt dissection technique with finger and vessel skeletonization in the posterior vesical wall for abnormally invasive placenta previa.

J Matern Fetal Neonatal Med 2018 Nov 28:1-71. Epub 2018 Nov 28.

a Department of Obstetrics and Gynecology , Gaziantep University , School of Medicine , Gaziantep , Turkey.

Purpose: This study described a new technique to minimize the bleeding resulted from aberrant engorged vessels and unintended bladder injury in cases with abnormally invaded placenta adjacent to posterior bladder wall at cesarean hysterectomy.

Methods: After filling the bladder with 300 ml saline aberrant engorged vessels were identified and skeletonized between lower uterine segment and bladder with blunt dissection by index finger down to the distal end point of cervix.

Results: This technique has beneficial effect on preventing bladder injury and reduces bleeding resulting from the aberrant vessels and the communicating vessels that were based around the vesicouterine fold and the cervico-vesical interface (in the lower part of the cervix); respectively. Read More

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November 2018

Updates on the management of placenta accreta spectrum.

Minerva Ginecol 2018 Nov 27. Epub 2018 Nov 27.

Women ́s Health and Perinatology Research Group, Department of Clinical Medicine, Faculty of Health Sciences, UiT-The Arctic University of Norway, Tromsø, Norway -

Placenta accreta spectrum (PAS) disorders is a multifactorial process that encompasses a heterogeneous group of conditions characterized by an abnormal invasion of trophoblastic tissue through the myometrium and uterine serosa. PAS is associated with a high burden of adverse maternal outcomes including severe life-threatening hemorrhage, need for blood transfusion, damage to adjacent organs, and death. Prenatal screening of PAS is mandatory so that women may be counselled about the severity of this condition to plan management with a multidisciplinary team and delivery in a specialized center. Read More

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November 2018
1 Read

Methotrexate Therapy for Ectopic Pregnancies: A Tertiary Center Experience.

Rev Bras Ginecol Obstet 2018 Nov 28;40(11):680-685. Epub 2018 Nov 28.

Division of Perinatology, Department of Obstetrics and Gynecology, Faculty of Medicine at Hacettepe University, Ankara, Turkey.

Objective:  Our aim is to demonstrate the importance of methotrexate (MTX) therapy for the treatment of ectopic pregnancy (EP).

Methods:  This retrospective study consisted of 99 patients (72 tubal EPs, 20 pregnancies of unknown location (PUL), 4 cesarean section (CS) scar EPs and 3 cervical EPs) treated with MTX.

Results:  Methotrexate therapy was successful in 68. Read More

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November 2018
1 Read

Association of chorioamnionitis and its duration with adverse maternal outcomes by mode of delivery: a cohort study.

BJOG 2018 Nov 28. Epub 2018 Nov 28.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of North Carolina (Chapel Hill, NC).

Objective: To investigate the association of chorioamnionitis and its duration with adverse maternal outcomes by mode of delivery.

Design: A retrospective cohort study.

Setting: Data from the Consortium on Safe Labor Study (CSL) in the USA (2002-2008). Read More

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November 2018
1 Read

Cesarean delivery rate and staffing levels of the maternity unit.

PLoS One 2018 28;13(11):e0207379. Epub 2018 Nov 28.

Paris School of Economics (PSE), Paris, France.

Objective: To investigate whether staffing levels of maternity units affect prelabor urgent, elective, and intrapartum cesarean delivery rates.

Methods: This population-based retrospective cohort study covers the deliveries of the 11 hospitals of a French perinatal network in 2008-2014 (N = 102 236). The independent variables were women's demographic and medical characteristics as well as the type, organization, and staffing levels for obstetricians, anesthesiologists, and midwives of each maternity unit. Read More

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November 2018

Hysterotomy level at cesarean section and occurrence of large scar defects: a randomized single-blind trial.

Ultrasound Obstet Gynecol 2018 Nov 28. Epub 2018 Nov 28.

Department of Obstetrics and Gynecology, St. Olavs hospital, Trondheim University Hospital, Trondheim, Norway.

Objective: To study the effect of cesarean hysterotomy level on the occurrence of large uterine scar defects 6-9 months after delivery.

Methods: This was a two-center, randomized, single-blind trial of a surgical procedure with masked assessment of the principal outcome under study. Women in active labor (cervix dilatation ≥5 cm) were randomized into a high incision (HIGH) or a low incision (LOW) group. Read More

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November 2018

Steroid hormone levels in the peripartum period - differences caused by fetal sex and delivery type.

Physiol Res 2018 Nov;67(Supplementum 3):S489-S497

Department of Obstetrics and Gynecology of the First Faculty of Medicine and General Teaching Hospital, Prague, Czech Republic, Institute of Endocrinology, Prague, Czech Republic.

Progesterone, estrogens, androgens and glucocorticoids all play important roles during pregnancy, from implantation to delivery. Focusing on selected steroid hormones in the peripartum period, we defined reference ranges measured using LS-MS/MS, and assessed relationships with maternal age, pregnancy weight gain, delivery type, and fetal sex. Samples were taken from 142 healthy women with physiological gravidity at the 37th week, during the first period of labor, and from newborn mixed cord blood. Read More

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November 2018

Obstetric practices in planned home births assisted in Brazil.

Rev Esc Enferm USP 2018 Nov 23;52:e03371. Epub 2018 Nov 23.

Universidade Federal de Santa Catarina, Departamento de Enfermagem, Programa de Pós-Graduação em Enfermagem, Florianópolis, SC, Brazil.

Objective: To describe obstetric practices in planned home births, assisted by qualified professionals in Brazil.

Method: This is a descriptive study, with data collected in an online bank maintained by 49 professionals from December 2014 to November 2015, in which the target population was women and newborns assisted in home births. Data were analyzed through descriptive statistics. Read More

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November 2018

Prophylactic infusion of phenylephrine is effective in attenuating the decrease in regional cerebral blood volume and oxygenation during spinal anesthesia for cesarean section.

Int J Obstet Anesth 2018 Sep 21. Epub 2018 Sep 21.

Department of Anesthesiology, Nihon University School of Medicine, 30-1 Oyaguchi-Kamicho, Itabashi-ku, Tokyo 173-8610, Japan.

Background: Hypotension induced by spinal anesthesia for cesarean section causes a decrease in maternal regional cerebral blood volume and oxygenation. We used near-infrared spectroscopy to determine whether prophylactic infusion of phenylephrine attenuates these decreases.

Methods: Sixty patients undergoing bupivacaine spinal anesthesia for cesarean section were randomly divided into one of three intravenous infusion groups: saline (P0), phenylephrine 25 (P25) or 50 µg/min (P50). Read More

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September 2018