69,113 results match your criteria Cesarean Delivery


Obstetrics outcome in pulmonary tuberculosis.

Indian J Tuberc 2022 Jul 7;69(3):305-310. Epub 2021 Jan 7.

Department of Obstetrics and Gynecology, AIIMS, New Delhi, India.

Background: To evaluate the maternal and perinatal outcome in pulmonary tuberculosis cases as compared to low risk pregnancies in a tertiary referral hospital.

Methods: A total of 15 cases of pulmonary tuberculosis over a period of two years who delivered in our unit was studied in the retrospective study. The maternal and perinatal outcome in them was compared with 191 low risk pregnancies who delivered at the same time in the hospital after taking into account inclusion and exclusion criteria. Read More

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Complications of second trimester induction for abortion or fetal demise for patients with and without prior cesarean delivery.

Contraception 2022 Jun 24. Epub 2022 Jun 24.

Rush University Medical Center, Department of Obstetrics and Gynecology. 1653 W Congress Parkway, Suite 208 Kellogg Chicago, IL, US 60612.

Objective: Compare complication rates of second trimester induction for abortion or fetal demise for patients with and without prior cesarean delivery.

Study Design: Retrospective cohort study examining induction for abortion or fetal demise for pregnancies from 14w0d-23w6d gestation at two urban academic medical centers from 2009-2019. Exclusion criteria included preterm labor or cervical insufficiency, neonatal interventions, or if misoprostol was not the primary induction method. Read More

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Obstetric Anesthesia Procedure-Based Workload and Facility Utilization of Society of Obstetric Anesthesia and Perinatology Centers of Excellence Designated Institutions.

Anesth Analg 2022 Jun 21. Epub 2022 Jun 21.

From the Department of Anesthesiology, Perioperative and Pain Medicine, Stanford School of Medicine, Palo Alto, California.

Background: Optimal workload and staffing for obstetric anesthesia services have yet to be determined. We surveyed Society of Obstetric Anesthesia and Perinatology (SOAP) Centers of Excellence (COE) for Obstetric Anesthesia Care institutions to evaluate procedure-based obstetric anesthesia workload and facility use.

Methods: After institutional review board (IRB) exemption, an online survey instrument (REDCap) was sent by email (1 initial and 2 reminders) to all SOAP COEs. Read More

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Evaluation of Developmental and Reproductive Toxicity in Rabbits for MB-102, a Fluorescent Tracer Agent Designed for Real-Time Measurement of Glomerular Filtration Rate.

Int J Toxicol 2022 Jun 27:10915818221111331. Epub 2022 Jun 27.

MediBeacon Inc., St. Louis, MO, USA.

The fluorescent tracer, MB-102, has been designed for the direct, real-time measurement of glomerular filtration rate. Previous studies, both and (rats, rabbits and dogs), were conducted to assess potential toxicity including single dose toxicity, mutation assay, chromosomal aberration assay, phototoxicity, local tolerance study, micronuclease assay, hERG channel changes, CNS and cardiovascular safety. The results of these studies led to a safety/toxicology profile for this agent deemed sufficient by the FDA to conduct Phase I and Phase II human clinical studies. Read More

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Prediction of the degree of abnormal invasive placentation by obstetric history.

Minerva Obstet Gynecol 2022 Jun 22. Epub 2022 Jun 22.

Department of Obstetrics and Gynecology, the Chaim Sheba Medical Center, Ramat-Gan, Israel.

Introduction: Diagnosis of placenta accrete spectrum (PAS) disorders is of utmost importance and mostly relies on high index of suspicion and sonographic criteria. The degree of abnormal invasive placentation is strongly associated with patients' outcomes. We aimed to determine the association between prior obstetric characteristics and the degree of PAS. Read More

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Implementing Professional Midwife-Led Maternity Care in India for Healthy Pregnant Women: A Community Case Study.

Front Public Health 2022 9;10:875595. Epub 2022 Jun 9.

UCLan THRIVE Centre, Research in Childbirth and Health (ReaCH) Unit, University of Central Lancashire, Preston, United Kingdom.

More women and neonates die each year in India than in almost every other country of the world. Since 1947, India has in principle provided free medical maternal health care to all pregnant and childbearing women. Although rates of maternal and neonatal deaths have fallen since the 1990s, major inequalities remain. Read More

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Sudden Onset of Severe Pulmonary Hypertension in a Preterm Infant: A Case Report on the Role of Maternal Use of Serotonin Re-Uptake Inhibitors During Pregnancy and Concurrent Risk Factors.

Front Pediatr 2022 10;10:855419. Epub 2022 Jun 10.

Division of Neonatal and Pediatric Intensive Care, Emergency Department, IRCCS Giannina Gaslini Institute, Genoa, Italy.

Persistent pulmonary hypertension of the newborn (PPHN) is a severe condition caused by failed circulatory adaptation at birth. Pulmonary hypertension is most common in full-term infants and rare in preterms, although it is increasingly diagnosed also in extremely preterm infants. Previous studies demonstrated the association between maternal use of selective serotonin re-uptake inhibitors during gestation and pulmonary hypertension. Read More

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An Observational Study of Therapeutic Hypothermia and Factors Associated With Mortality in Late-Preterm and Term Neonates With Hypoxic-Ischemic Encephalopathy in a Middle-Income Country.

Front Pediatr 2022 10;10:894735. Epub 2022 Jun 10.

Department of Paediatrics, Selayang Hospital, Ministry of Health, Batu Caves, Malaysia.

Objectives: To investigate the types of therapeutic hypothermia (TH) used and risk factors associated with mortality in late-preterm and term neonates (LPTN, gestation of ≥35 weeks) with hypoxic-ischemic encephalopathy (HIE) in a middle-income country.

Design: This was an observational retrospective cohort study.

Setting: A total of 44 neonatal intensive care units (NICUs) in the Malaysian National Neonatal Registry participated in the study. Read More

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Evaluation of Antepartum Factors for Predicting the Risk of Emergency Cesarean Delivery in Pregnancies Complicated With Placenta Previa.

Ochsner J 2022 ;22(2):146-153

Department of Obstetrics and Gynecology, Health Sciences University, Gazi Yaşargil Training and Research Hospital, Diyarbakır, Turkey.

The optimal delivery timing for patients with placenta previa remains controversial in the literature. To reduce spontaneous vaginal bleeding rates, which occur increasingly with advancing gestational weeks, elective cesarean delivery is advocated between 36 and 37 weeks of gestation, but this clinical approach does not take into consideration numerous patient variables. Few papers identify the risk factors for emergency cesarean delivery in patients with placenta previa. Read More

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January 2022

A Height-Based Dosing Algorithm of Bupivacaine in Spinal Anesthesia for Decreasing Maternal Hypotension in Cesarean Section Without Prophylactic Fluid Preloading and Vasopressors: A Randomized-Controlled Non-Inferiority Trial.

Front Med (Lausanne) 2022 10;9:858115. Epub 2022 Jun 10.

Department of Anesthesiology, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College of Guangzhou University of Chinese Medicine, Shenzhen, China.

Background: There is a high incidence of maternal hypotension in spinal anesthesia for cesarean section. The aim of the study is to investigate whether there is a height-based dosing algorithm of bupivacaine that provides adequate anesthesia with less maternal hypotension.

Methods: There were 2 groups of 280 parturients who did not receive prophylactic fluid preloading: Test and Conventional group. Read More

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Peripartum and Postpartum Analgesia and Pain in Women Prescribed Buprenorphine for Opioid Use Disorder Who Deliver by Cesarean Section.

Subst Abuse 2022 21;16:11782218221107936. Epub 2022 Jun 21.

Department of Pharmacy Practice, Westbrook College of Health Professions, University of New England, Portland, ME, USA.

Aim: Little is known about whether pain can be effectively managed in pregnant women with opioid use disorder (OUD) during delivery hospitalization, particularly those undergoing surgery and taking buprenorphine as medication for OUD (MOUD). To address this question, we compared pain scores and opioid analgesic utilization during delivery hospitalization in women taking their pre-hospital dose of buprenorphine who delivered by cesarean section to matched controls. To inform future research efforts, we also began to explore opioid analgesic utilization and pain scores by type of anesthesia as this variable is often not included in related literature. Read More

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Non-invasive continuous blood pressure monitoring using the ClearSight system for pregnant women at high risks of post-partum hemorrhage: comparison with invasive blood pressure monitoring during cesarean section.

Obstet Gynecol Sci 2022 Jun 27. Epub 2022 Jun 27.

Department of Obstetrics and Gynecology, Faculty of Medicine, Osaka Metropolitan University, Abeno Ward, Japan.

Objective: This study aimed to investigate the accuracy and precision of continuous, non-invasive blood pressure obtained using the ClearSight system by comparing it with invasive arterial blood pressure, and to assess the hemodynamic changes using the ClearSight system in patients undergoing cesarean section.

Methods: Arterial pressure was measured invasively with an intra-arterial catheter and non-invasively using the ClearSight system during cesarean section in patients with placenta previa or placenta accreta. Blood pressure measurements obtained using these two means were then compared. Read More

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Fundal pressure to shorten the second stage of labor: Systematic review and meta-analysis.

Eur J Obstet Gynecol Reprod Biol 2022 Jun 13;275:70-83. Epub 2022 Jun 13.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA, USA. Electronic address:

Objectives: Systematically review the evidence on fundal pressure to expedite vaginal delivery.

Study Design: Literature search in electronic databases. Randomized controlled trials of fundal pressure to expedite delivery were included in this systematic review and meta-analysis. Read More

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Treatment for clear cell carcinoma of the abdominal wall at a tertiary cancer center.

Sci Rep 2022 Jun 25;12(1):10820. Epub 2022 Jun 25.

Department of Gynecological Oncology, Fudan University Shanghai Cancer Center, 270 Dong-an Road, Shanghai, 200032, China.

Clear cell carcinoma (CCC) of the abdominal wall is a rare and agressive disease. We aim to elucidate the clinical and prognostic characteristics of this disease. Medical records of ten patients diagnosed with CCC of the abdominal wall at Fudan University Shanghai Cancer Center were reviewed. Read More

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The Optimal Cesarean Skin Incision in Patients with Super Obesity.

Am J Perinatol 2022 Jun 25. Epub 2022 Jun 25.

Department of Obstetrics and Gynecology and Reproductive Sciences, University of Maryland Medical Center, Baltimore, United States.

Objective To evaluate if supraumbilical midline vertical incision performed in patients with a hanging pannus (umbilicus at the level of the pubic bone) is a reasonable alternative to Pfannenstiel in patients with Body Mass Index (BMI) ≥ 50 kg/m2 undergoing cesarean delivery. Methods Retrospective cohort study in patients with BMI ≥50 kg/m2 undergoing cesarean delivery at a single center from 2016 to 2020. Study groups were Pfannenstiel VS supraumbilical vertical skin incision. Read More

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Applying automated machine learning to predict mode of delivery using ongoing intrapartum data in laboring patients.

Am J Perinatol 2022 Jun 25. Epub 2022 Jun 25.

OB-GYN, Cedars-Sinai Medical Center Department of Obstetrics and Gynecology, Los Angeles, United States.

OBJECTIVE To develop and validate a machine learning model to predict the probability of a vaginal delivery (Partometer) using data iteratively obtained during labor from the electronic health record. STUDY DESIGN A retrospective cohort study of deliveries at an academic, tertiary care, hospital from 2013-2019 who had at least 2 cervical exams. The population was divided into those delivered by physicians with nulliparous term singleton vertex (NTSV) cesarean delivery rates < 23. Read More

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Leaving the Placenta In Situ in Placenta Accreta Spectrum Disorders: A Single Center Case Series.

Am J Perinatol 2022 Jun 25. Epub 2022 Jun 25.

Obstetrics & Gynecology, University of Texas Health Sciences Center at Houston, Houston, United States.

The most common treatment for placenta accreta spectrum disorders (PAS) is planned primary cesarean-hysterectomy. However, other management strategies may improve outcomes and/or allow fertility preservation. This is a series of 11 patients with PAS managed by leaving the placenta in situ at a single academic center in the U. Read More

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A bias away from Th2 in amniotic fluid is involved in preeclampsia.

J Reprod Immunol 2022 Jun 11;152:103656. Epub 2022 Jun 11.

Department of Anesthesia, Peking University Third Hospital, China. Electronic address:

Inflammatory cytokines contribute to the pathophysiology of preeclampsia. However, whether the imbalance of Th1/Th2 cytokines in amniotic fluid is associated with preeclampsia is not well defined. In the present study, we collected peripheral blood and amniotic fluid from normal pregnancy (n = 25) and preeclampsia (n = 22) at last trimester during cesarean section. Read More

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Methods of induction of labor after cesarean with no prior vaginal delivery - perinatal outcomes.

Int J Gynaecol Obstet 2022 Jun 25. Epub 2022 Jun 25.

Department of Obstetrics and Gynecology, Chaim Sheba Medical Center, Ramat-Gan, Israel.

Objective: To study the association between the method of induction of labor (IOL) and perinatal outcomes, among women undergoing labor after cesarean (LAC) with no prior vaginal delivery.

Method: A retrospective study including all women with no prior vaginal delivery undergoing IOL for LAC between 3/2011 - 1/2021. Oxytocin administration following prelabor rupture of membranes, oxytocin administration only, extraamniotic balloon and amniotomy were compared. Read More

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Maternal and perinatal outcomes in women ≥40 years undergoing induction of labor compared with women <35 years: Results from 4027 mothers.

J Obstet Gynaecol Res 2022 Jun 25. Epub 2022 Jun 25.

Fetal Medicine Unit, Department Obstetrics, Gynecology, Reproductive Medicine, Hospital Universitari Quiron Dexeus, Barcelona, Spain.

Aim: Cesarean section is known to be increased with advanced maternal age in women undergoing induction of labor (IOL), but there is less information regarding other possible adverse maternal and fetal outcomes.

Methods: Retrospective cohort study of singleton, nulliparous, at-term women undergoing IOL between January 2007 and September 2020. Outcomes studied were: cesarean section, failed induction rate, fetal distress, post-partum hemorrhage, post-partum hysterectomy, and need of transfusion. Read More

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Risk factors of extrauterine growth restriction in very preterm infants with bronchopulmonary dysplasia: a multi-center study in China.

BMC Pediatr 2022 Jun 24;22(1):363. Epub 2022 Jun 24.

Department of Pediatrics, Peking University Third Hospital, Beijing, China.

Objective: Nutritional deficiency soon after birth is a risk factor of chronic lung disease (bronchopulmonary dysplasia, BPD). Afflicted infants are further prone to inadequate growth during hospitalization (extrauterine growth restriction, EUGR). This multi-center retrospective study investigated risk factors of EUGR, specifically in very preterm infants with BPD. Read More

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A Quality Improvement Effort to Reduce Inpatient Opioid Consumption following Cesarean Delivery.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Department of Obstetrics and Gynecology, Division of Maternal Fetal Medicine, University of North Carolina at Chapel Hill School of Medicine, Chapel Hill, United States.

Objective: The amount of opioid prescribed following cesarean delivery is commonly in excess of patients' needs. An additional concern in a breastfeeding mother is neonatal opioid exposure. A maximum daily dose of 30 mg of oxycodone is recommended in breastfeeding women. Read More

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Impaired fasting glucose in pregnancy: improved perinatal outcomes with active glycemic management.

Am J Perinatol 2022 Jun 24. Epub 2022 Jun 24.

Perinatology, Kaiser Permanente Oakland Medical Center, Oakland, United States.

Objective: To assess the association between active glycemic management and large for gestational age (LGA) neonates and cesarean delivery (CD) among pregnant women with impaired fasting glucose (IFG).

Study Design: Retrospective cohort study using electronic health record data of women with IFG who delivered at Kaiser Permanente Northern California from 2012-2017. IFG was defined as isolated fasting glucose ≥95 mg/dL. Read More

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Implementation of telemedicine preoperative visits for abortion procedures through 18 weeks gestation at a Northern California hospital-based center.

Contraception 2022 Jun 21. Epub 2022 Jun 21.

Department of Obstetrics and Gynecology, University of California, Davis; Sacramento, CA.

Objective: Describe the implementation of a preoperative telemedicine program at a Northern California hospital-based center for abortion procedures requiring cervical preparation.

Study Design: We implemented a pilot program using telemedicine for preoperative visits for patients needing cervical preparation prior to an abortion procedure from 12 to 18 weeks. We required ultrasonography for gestational age documentation in addition to placental localization in patients with a prior cesarean delivery. Read More

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Maternal obesity-associated disruption of polarized lactate transporter MCT4 expression in human placenta.

Reprod Toxicol 2022 Jun 22;112:1-6. Epub 2022 Jun 22.

Department of Obstetrics, Gynecology, and Reproductive Sciences, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:

Maternal obesity is associated with an increased risk of adverse pregnancy outcomes including stillbirth, and their etiology is thought to be related to placental and fetal hypoxia. In this study, we sought to investigate the levels of lactate in maternal and umbilical cord blood, a well characterized biomarker for hypoxia, and expression of plasma membrane lactate transporter MCT1 and MCT4 in the placental syncytiotrophoblast (STB), which are responsible for lactate uptake and extrusion, respectively, from pregnant women with a diagnosis of obesity following a Cesarean delivery at term. With use of approaches including immunofluorescence staining, Western blot, RT-qPCR and ELISA, our results revealed that in controls the expression of MCT1 was equally observed between basal (fetal-facing, BM) and microvillous (maternal-facing, MVM) membrane of the STB, whereas MCT4 was predominantly expressed in the MVM but barely detected in the BM. Read More

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The problem of the risk of development of infection of surgical obstetric wound after cesarian section in women of the Kirov region.

Klin Lab Diagn 2022 Jun;67(6):374-379

Kirov State Medical University.

Over the past decade, the frequency of abdominal delivery in Russia has increased to an average of 25 %. The widespread use of abdominal delivery has not been without an increase in the incidence of complications. Among them is an infectious complication of a surgical obstetric wound (ICD O86. Read More

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Placental location and obstetrical-neonatal outcomes - A retrospective study.

Int J Gynaecol Obstet 2022 Jun 24. Epub 2022 Jun 24.

Helen Schneider Hospital for Women, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Israel.

Objective: To explore the potential association of lateral placentation with pregnancy outcome.

Methods: The database of a tertiary medical center was searched for women who gave birth to a singleton infant in 2012-2020 for whom placental location was documented during antepartum sonographic examination. Clinical data were compared between patients with a central (anterior/posterior/fundal) or lateral placenta using standard statistics. Read More

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Hepatitis C is associated with more adverse pregnancy outcomes than hepatitis B: A 7-year national inpatient sample study.

Hepatol Commun 2022 Jun 24. Epub 2022 Jun 24.

Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, New York, New York, USA.

Prior international studies have shown mixed results regarding the association of hepatitis B and hepatitis C with adverse pregnancy outcomes. We performed an updated evaluation of the prevalence of associated adverse pregnancy outcomes and evaluated trends over time of diagnosis of chronic hepatitis B (HBV) and chronic hepatitis C (HCV) in pregnant women in a national database. All pregnant women with HBV and HCV were identified from the National Inpatient Sample database 2012 to 2018. Read More

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Post-cesarean severe sepsis and uterine wound disruption presenting as abdominal wound abscess and peritonitis: A case report.

SAGE Open Med Case Rep 2022 16;10:2050313X221105922. Epub 2022 Jun 16.

Department of Obstetrics and Gynaecology, Faculty of Postgraduate Medicine, Khesar Gyalpo University of Medical Sciences of Bhutan, Thimphu, Bhutan.

With increasing rate of cesarean section in Bhutan, the complications are expected to rise. Uterine scar dehiscence is one of the immediate complications of cesarean section, which has high morbidity and mortality. Herein, we report a case of uterine wound dehiscence with pelvic abscess following cesarean section, who presented with paralytic ileus and surgical site infection. Read More

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Hysteroscopy-Guided Natural Orifice Repair of Isthmocele.

Gynecol Minim Invasive Ther 2022 Apr-Jun;11(2):116-118. Epub 2022 May 4.

Department of Gynecology and Obstetric, Bakirkoy Dr. Sadi Konuk Education and Research Hospital, University of Health Sciences, Istanbul, Turkey.

Isthmocele can be defined as a hypoechoic field within the lower uterine segment, indicating a discontinuation of the myometrium at the uterine scar of a previous cesarean section. Postmenstrual spotting, pelvic pain, dysmenorrhea, dyspareunia, uterine rupture, cesarean scar pregnancy, and secondary infertility could be seen as the complications of existing isthmocele. Such defects are prevalent with the increasing number of cesarean deliveries. Read More

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