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Eur Arch Otorhinolaryngol 2018 Dec 3. Epub 2018 Dec 3.

Department of Cervicofacial and ENT Surgery, Faculty of Dentistry, "Iuliu Hațieganu" University of Medicine and Pharmacy Cluj-Napoca, Str. Gheorghe Bilascu Nr. 16-20, Cluj-Napoca, Romania.

Purpose: The risk of temporal bone fractures in head trauma is not negligible, as injuries also depend on the resistance and integrity of head structures. The capacity of mastoid cells to absorb part of the impact kinetic energy of the temporal bone is diminished after open cavity mastoidectomy, even if the surgical procedure is followed by mastoid obliteration. The aim of our study was to evaluate the severity of lesions in auditory anatomical structures after a lateral impact on cadaveric temporal bones in which open cavity mastoidectomy followed by mastoid obliteration was performed, compared to cadaveric temporal bones with preserved mastoids. Read More

Iran J Med Sci 2018 Nov;43(6):653-658

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Lagos State University College of Medicine, Lagos State, Nigeria.

Necrotizing fasciitis of the head and neck is a rare but rapidly progressive infection involving the skin, subcutaneous tissue, and fascia. We report 4 cases of cervicofacial necrotizing fasciitis with similar patterns of presentation. All the 4 cases presented with an odontogenic source and no underlying medical condition. Read More

J Plast Reconstr Aesthet Surg 2018 Nov 16. Epub 2018 Nov 16.

Department of Plastic Surgery, University and University Medical School of Groningen & Bey Bergman Clinics, The Netherlands, P.O. Box 30.001, 9700 RB Groningen, The Netherlands. Electronic address:

Vasc Endovascular Surg 2018 Nov 29:1538574418814057. Epub 2018 Nov 29.

4 ENT Clinic of Red Cross Hospital, Athens, Greece.

Lymphangiomas are rare benign malformations of the lymphatic system, commonly present in children, over the head and neck area. Occasionally, they can grow significantly in size and especially those located over the cervical region can cause airway obstruction and become life-threatening. Recurrent lymphangiomas usually occur during the early postsurgical period and 80% of them within the first 3 to 5 years. Read More

Diagn Cytopathol 2018 Nov 29. Epub 2018 Nov 29.

Department of Pathology, Loyola University Medical Center, Maywood, Illinois.

J Oral Maxillofac Surg 2018 Oct 24. Epub 2018 Oct 24.

Private Practice, Cosmetic Facial Surgery, Midlothian, VA. Electronic address:

Purpose: Pyoderma gangrenosum (PG) is an uncommon autoimmune, neutrophilic, ulcerative skin condition of uncertain etiology believed to result from dysregulation of the immune system. Although this entity is well recognized by dermatologists, other specialists are less familiar with diagnosis and treatment. This report describes a severe PG reaction to an elective cosmetic facelift, which is believed to be the second reported case of PG after facelift surgery. Read More

Head Neck 2018 Nov 17. Epub 2018 Nov 17.

Department of Head and Neck Surgery, Centre Antoine Lacassagne, Nice, France.

Background: Preservation of facial harmony is a major challenge in reconstruction after resection of head and neck skin tumors. For large medial cheek-skin defects, we used a derived posterior-based cervicofacial flap, or cervical-medial cheek flap (CMCF).

Methods: We present a retrospective review of cases treated at a university-based cancer center. Read More

Facial Plast Surg Clin North Am 2019 Feb;27(1):55-66

Department of Otolaryngology, University of Colorado School of Medicine, 12631 East 17th Avenue, B205, Aurora, CO 80045-2527, USA. Electronic address:

The goal of cheek reconstruction is to restore an illusion of "normal." Attention must be directed toward the contralateral cheek skin color, texture, thickness, and contour, because this serves a template for reconstruction. The cheek is a peripheral facial subunit and largely frames the more central subunits (eyelids, nose, lips). Read More

Infection 2018 Nov 8. Epub 2018 Nov 8.

Dorevitch Pathology, 18 Banksia St, Heidelberg, Melbourne, 3084, Australia.

Introduction: Actinomyces spp. cause several well-described syndromes including cervicofacial and pelvic infections. Actinomyces spp. Read More

Eur Arch Otorhinolaryngol 2018 Nov 7. Epub 2018 Nov 7.

ENT and Cervicofacial Surgery Department, Fundación Jiménez Díaz University Hospital, Madrid, Spain.

Background: Septal perforations consist in an anatomic defect of the mucosal, cartilaginous and/or bone tissues of the nasal septum. A huge variety of approaches and techniques for nasal perforation repair have been reported.

Methodology/principal: Between January 2008 and January 2017, 38 patients were treated for nasal septal perforation in Department of Otorhinolaryngology Head and Neck Surgery, Fundación Jiménez Díaz University Hospital, Madrid, Spain. Read More

J Korean Assoc Oral Maxillofac Surg 2018 Oct 26;44(5):212-219. Epub 2018 Oct 26.

Department of Oral and Maxillofacial Surgery, Gangnam Severance Hospital, Yonsei University College of Dentistry, Seoul, Korea.

Objectives: The objective of this study was to analyze 11 cases of subcutaneous emphysema associated with dental procedures from a single hospital and discuss approaches for accurate diagnosis and treatment of the condition.

Materials And Methods: The medical records of 11 patients who were treated for subcutaneous emphysema related to dental procedures between January 2009 and April 2017 were analyzed retrospectively. Patients with subcutaneous emphysema within the facial area or that spread to the neck and beyond, including the facial region, were assigned to two groups and compared in terms of age, sex, and durations of antibiotic use, hospitalization, and follow-up until improvement. Read More

Eur Arch Otorhinolaryngol 2018 Oct 30. Epub 2018 Oct 30.

Department of Otolaryngology, Facial Plastic and Cervicofacial Surgery, Edouard Herriot Hospital, 5 place d'Arsonval, 69437, Lyon Cedex 03, France.

Introduction: The aim of our study is to compare the functional results between two surgical techniques for reanimation of facial paralysis: hypoglossal-to-facial versus masseteric-to-facial nerve anastomosis.

Methods: This is a retrospective study of 13 patients treated for complete facial paralysis in two medical tertiary centers. The patients were classified into two groups. Read More

Ann Otol Rhinol Laryngol 2018 Oct 29:3489418808541. Epub 2018 Oct 29.

1 Department of Otolaryngology-Head and Neck Surgery, University of Kansas Health System, Kansas City, KS, USA.

Background:: Cervicofacial actinomycosis is an uncommon indolent infection caused by Actinomyces spp that typically affects individuals with innate or adaptive immunodeficiencies. Soft tissues of the face and neck are most commonly involved. Actinomyces osteomyelitis is uncommon; involvement of the skull base and temporal bone is exceedingly rare. Read More

Aust Dent J 2018 Oct 1. Epub 2018 Oct 1.

The University of Queensland (UQ), Wide Bay Hospital and Health Services (WBHHS), Brisbane, Queensland, Australia.

Subcutaneous facial emphysema (SFE) following routine dental operative procedure is an uncommon but potentially life-threatening complication. The present case details a Class V restoration where air was introduced into the fascial tissue planes via the gingival sulcus from the use of an air-driven dental handpiece. Although the SFE is usually self-limiting within 3-10 days, such instances should be regarded as a medical emergency as in severe cases, the air may spread to the neck, mediastinum and thorax to result in cervicofacial emphysema with potential pneumomediastinum and pneumothorax. Read More

Clin Plast Surg 2018 Oct 10;45(4):485-506. Epub 2018 Aug 10.

Clinica Gomez Bravo, Calle Claudio Coello 76, Madrid 28001, Spain. Electronic address:

A description of the deep structures of the neck that are responsible for submandibular fullness and a systematic surgical approach to reduce them are presented. The structures susceptible to surgical management include the subplatysmal fat, inter-sternocleidomastoid origin fat, anterior belly of the digastric muscle, hyoid bone, submandibular gland and the tail of the parotid gland. A thorough analysis of the key anatomic landmarks of the young and attractive neck is detailed in resting and dynamic positions. Read More

Head Neck Pathol 2018 Sep 22. Epub 2018 Sep 22.

Department of Stomatology, University of Montreal Hospital Center, Montreal, QC, Canada.

Cervicofacial actinomycosis is a common form of Actinomyces infection. However, the latter seldom occurs in the tongue. We present a case of a 66 year-old man with macroglossia caused by actinomycosis of the tongue. Read More

Diseases 2018 Sep 6;6(3). Epub 2018 Sep 6.

Dianon Labcorp, Tampa, FL 33607, USA.

Periapical actinomycosis is a relatively rare form of cervicofacial actinomycosis, which typically involves the periapical region with subsequent potential spread to the jaw bones. We hereby present two cases of periapical actinomycosis. Both patients presented with jaw pain and "holes" in their gum and lacked the characteristic clinical features commonly seen in cervicofacial actinomycosis such as jaw mass, draining ulcers, sinuses and fistulae. Read More

J Plast Reconstr Aesthet Surg 2018 Dec 28;71(12):1816-1834. Epub 2018 Aug 28.

Service de Chirurgie Maxillo-Faciale, Groupe Hospitalier Paris Saint-Joseph, 185 rue Raymond Losserand, Paris, France.

J Plast Reconstr Aesthet Surg 2018 Dec 28;71(12):1816-1834. Epub 2018 Aug 28.

Department of Oral and Maxillofacial Surgery, Rouen Universitary Hospital, 1 rue de Germont, F-76031 Rouen, France; Laboratory of Anatomy, Rouen Faculty of Medicine, Rouen-Normandy University, 22 boulevard Léon-Gambetta, F-76183-1 Rouen, France. Electronic address:

Acta Med Port 2018 Aug 31;31(7-8):435-439. Epub 2018 Aug 31.

Serviço de Medicina Interna III. Centro Hospitalar Lisboa Norte. Lisboa. Portugal.

Subcutaneous emphysema is a possible but rare complication after dental procedures. The condition should be distinguished from other situations, such as hematoma, allergic reaction or angioedema, and infection. We describe the case of a 20-year-old puerperal woman, with multiple dental caries, who developed cervicofacial subcutaneous emphysema complicated by pneumomediastinum, following an incomplete extraction of the lower right second molar. Read More

Respir Med Case Rep 2018 25;25:158-160. Epub 2018 Aug 25.

Staten Island University Hospital, USA.

Actinomycosis is an uncommon infectious disease caused predominantly by Actinomyces israelii. Actinomycosis usually involves the cervicofacial, thoracic, abdominal, and pelvic region, dissemination is uncommon. Actinomyces viscosus are commensal organisms that make up the normal flora of the oropharynx of humans and has rarely been reported to cause disease. Read More

Plast Reconstr Surg 2018 Sep;142(3):425e-426e

Division of Plastic and Reconstructive Surgery, Department of Surgery, Medical University of Vienna Plastic and Reconstructive Surgery, Department of Surgery, Hospital of the Divine Savior (Krankenhaus Goettlicher Heiland) Department of Anatomy, Centre for Anatomy and Cell Biology Division of Plastic and Reconstructive Surgery, Department of Surgery Division of Cardiovascular and Interventional Radiology Nuclear Medicine, Department of Biomedical Imaging and Image-Guided Therapy Division of Plastic and Reconstructive Surgery, Department of Surgery Department of Anatomy, Centre for Anatomy and Cell Biology, Medical University of Vienna Plastic and Reconstructive Surgery, Department of Surgery, Hospital of the Divine Savior (Krankenhaus Goettlicher Heiland), Vienna, Austria.

Neurobiol Learn Mem 2018 Aug 17;155:276-286. Epub 2018 Aug 17.

Department of Experimental Medicine Section of Physiology and Biochemistry, University of Perugia, 06127 Perugia, Italy. Electronic address:

Neurosteroid 17 beta-estradiol (E2) is a steroid synthesized de novo in the nervous system that might influence neuronal activity and behavior. Nevertheless, the impact of E2 on the functioning of those neural systems in which it is slightly synthesized is less questioned. The vestibulo-ocular reflex (VOR) adaptation, may provide an ideal arena for investigating this issue. Read More

Pan Afr Med J 2018 6;29:202. Epub 2018 Apr 6.

Service de Dermatologie, CHU Hassan II, Fes, Maroc.

Superficial circumscribed lymphangiomas are predominantly benign lesions occuring in the cervicofacial area. These malformations of the lymphatic vessels are frequently diagnosed in children. We report the clinical case of lymphangioma of the tongue that occurred in an old man. Read More

Int J Pediatr Otorhinolaryngol 2018 Sep 19;112:48-54. Epub 2018 Jun 19.

Department of Oral and Maxillofacial Surgery, Academic Medical Center, Amsterdam, The Netherlands; Department of Head and Neck Oncology and Surgery, Netherlands Cancer Institute/Antoni Van Leeuwenhoek Hospital, Amsterdam, The Netherlands.

Objectives: Widespread controversy exists regarding correct diagnosing nontuberculous mycobacterial cervicofacial (NTM) lymphadenitis. This study intends to gather the available evidence with respect to diagnosing NTM cervicofacial lymphadenitis.

Methods: A review protocol was developed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA)-statement (www. Read More

Transpl Infect Dis 2018 Dec 11;20(6):e12970. Epub 2018 Aug 11.

Department of Nephrology and Transplant Federation, François Mitterrand University Hospital, Dijon, France.

Actinomycosis is a rare and heterogeneous infection involving Gram-positive anaerobic bacteria, which are commensals in the oral cavity and digestive tract. Only four cases of actinomycosis in renal transplant recipients have been reported to date. We performed a retrospective study in French renal transplantation centers to collect data about actinomycosis, patients, and transplantation. Read More

Pan Afr Med J 2018;29:155. Epub 2018 Mar 15.

Service d'Oto-Rhino-Laryngoglogie, CHU Farhat Hached, Sousse, Tunisie.

This retrospective study aimed to highlight the different epidemiological, clinical, therapeutic and prognostic features of nasopharinx cancer with inaugural metastases in patients hospitalized in a Tunisian Hospital. We here report 51 cases of histologically diagnosed nasopharynx cancer (NPC) with inaugural metastases. Data were collected in the ENT departments and in the radiation therapy departments at the University Hospital Farhat Hached, Sousse, Tunisia as well as at the Centre Medical Ibn Khaldoun, Hammam Sousse, between January 1995 and December 2010. Read More

Neurologia 2018 Jul 19. Epub 2018 Jul 19.

Hospital Clínico San Carlos, Madrid, España.

Objectives: Orofacial and cervical pain are a frequent reason for neurology consultations and may be due to multiple pathological processes. These include Eagle syndrome (ES), a very rare entity whose origin is attributed to calcification of the stylohyoid ligament or elongation of the temporal styloid process. We present a series of five patients diagnosed with ES. Read More

Ann Otol Rhinol Laryngol 2018 Oct 21;127(10):687-693. Epub 2018 Jul 21.

1 Department of Otolaryngology and Communication Enhancement, Boston Children's Hospital, Boston, Massachusetts, USA.

Objective(s): The objective was to describe the characteristics of hearing losses documented in patients treated with clarithromycin alone for nontuberculous mycobacterial NTM lymphadenitis in a pediatric tertiary care center over a 12-year period.

Methods: An institutional review board (IRB) approval was obtained. A database search was performed using the ICD-10 diagnosis codes 31. Read More

Plast Reconstr Surg 2018 Jun 26. Epub 2018 Jun 26.

J Craniofac Surg 2018 Nov;29(8):e754-e757

Department of Radiology, the First Affiliated Hospital of Dali University, Dali, China.

Objective: To explore the value of micro surface coil combined with three-dimensional reversed fast imaging with steady-state precession and diffusion-weighted imaging (3D-PSIF-DWI) in displaying intraparotid facial nerves and parotid ducts.

Methods: In total 24 healthy volunteers with no parotid disease underwent scanning of head and neck coil and 4-cm micro surface coil combined with 3D-PSIF-DWI prospectively. The obtained original images were processed through maximum intensity projection, multiplanar reconstruction, and curved planar reconstruction. Read More

J Craniofac Surg 2018 Sep;29(6):e617-e618

Department of Surgery and Integrated Clinics, School of Dentistry, São Paulo State University (UNESP), Araçatuba, Brazil.

Necrotizing fasciitis (NF) is a devastating disease that typically affects immunocompromised patients, chronically debilitated patients or drug users, but can also affect healthy patients. Necrotizing fasciitis can rapidly produce septic shock and requires immediate surgical management of the necrotic tissue. It is a bacterial infection that progresses rapidly and has a high mortality generally caused by aerobic and anaerobic bacteria. Read More

Presse Med 2018 Jul - Aug;47(7-8 Pt 1):702-704. Epub 2018 Jun 13.

Hôpital Farhat Hached, service de dermatologie, avenue Ibn Jazzar, 4000 Sousse, Tunisie.

Australas J Dermatol 2018 Jun 4. Epub 2018 Jun 4.

Department of Pediatrics, Children's Hospital, Zagreb, Croatia.

Clin Pract Cases Emerg Med 2017 Nov 3;1(4):399-402. Epub 2017 Nov 3.

KK Women's and Children's Hospital, Department of Pediatric Emergency Medicine, Singapore.

Idiopathic pediatric pneumoparotitis, being rare, is often misdiagnosed in acute care settings, resulting in inappropriate initial management and emergency department (ED) disposition. We report the case of a previously well 11-year-old boy who presented to our ED with acute left cheek swelling and pain. He was diagnosed with pneumoparotitis with cervicofacial subcutaneous emphysema with the aid of point-of-care ultrasound (POCUS) and radiographs. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2018 Jan;32(1):118-124

Department of Cervicofacial Plastic and Reconstructive Surgery, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College, Beijing, 100144,

Objective: To summarize the monitoring methods and preventions of the disorder of blood supplying of expanded flaps, so as to provide some references for improving the survival of expanded flaps.

Methods: The domestic and abroad related literature about the disorder of blood supplying of expanded flaps was reviewed and analyzed.

Results: Handheld Doppler, digital subtraction angiography, computer tomographic angiography, magnetic resonance angiography, and fluorescein angiography can be used as reliable preoperative imaging methods in designing expanded flaps with rich blood supply. Read More

Ann Dermatol Venereol 2018 Aug - Sep;145(8-9):505-511

Service de dermatologie, CHU d'Angers, 4, rue Larrey, 49100 Angers, France.

Background: Cervical lymphadenitis is the most common manifestation of infection with nontuberculous mycobacteria (NTM) in immunocompetent children. Nevertheless, it is poorly known by dermatologists. Its incidence, which is currently increasing since the cessation of BCG vaccination in 2007, raises several issues regarding its pathophysiology, diagnosis and management. Read More

Int J Oral Maxillofac Surg 2018 Dec 8;47(12):1609-1612. Epub 2018 May 8.

National University Health System, Singapore.

Third molar extraction is a common procedure in dental surgery. Common complications that may occur post procedure include pain, trismus, bleeding, dry socket, and nerve injuries. Subcutaneous emphysema is an uncommon complication. Read More

J Infect Public Health 2018 Apr 26. Epub 2018 Apr 26.

Department of Pediatric, College of Medicine, King Saud University and King Saud University Medical City, Riyadh, Saudi Arabia. Electronic address:

Actinomycosis is a rare infection in patients younger than 10years of age. It mainly affects the cervicofacial region, but many other sites of infection have been recognized. About 70% of infections are due to either Actinomyces israelii or Actinomyces gerencseriae. Read More

Oral Oncol 2018 May 4;80:56-63. Epub 2018 Apr 4.

Univ Rennes, Inserm, EHESP, Irset (Institut de recherche en santé, environnement et travail) - UMR_S 1085, Pointe-à-Pitre, France.

Objectives: Epidemiological studies on the risk factors for salivary gland cancers (SGC) are rare, concern a small sample size, and show inconsistent results. The aim of the present work was to analyze several risk factors for SGC, using the data from the ICARE study, a multicenter, population-based case-control study.

Materials And Methods: Data from 73 SGC cases and 3555 controls were collected using a standardized questionnaire on lifestyle habits, personal and family medical history, and lifetime occupational history. Read More

Ann Stomatol (Roma) 2017 Sep-Dec;8(3):117-122. Epub 2018 Mar 8.

Department of Oral and Maxillofacial Sciences, "Sapienza" University of Rome, Rome, Italy.

Introduction: Cervicofacial subcutaneous emphysema is defined as the abnormal introduction of air in the subcutaneous tissues of the head and neck. It is mainly caused by trauma, head and neck surgery, general anesthesia, and coughing or habitual performance of Valsalva manoeuvre. The occurrence of subcutaneous emphysema after dental treatment is rare, and diffusion of gas into the mediastinum is much rarer, especially when the procedure is a nonsurgical treatment. Read More

Indian J Ophthalmol 2018 05;66(5):722-724

Haydarpasa Numune Education and Research Hospital, Eye Clinic, Istanbul, Turkey.

Cervicofacial emphysema (CFE), mostly seen after trauma or dental procedures, is an unexpected, extremely rare condition after uncomplicated dacryocystorhinostomy (DCR). It may be misdiagnosed as angioedema or necrotizing fasciitis. In this article, we present the case of a 40-year-old female with CFE twice after uncomplicated unilateral DCR for left and right sides on different operative days. Read More

BMJ Case Rep 2018 Apr 19;2018. Epub 2018 Apr 19.

Division of Respiratory Medicine, National Hospital Organization Kyoto Medical Center, Kyoto, Japan.

Cutaneous lymphangitis carcinomatosa (CLC) is a rare form of cutaneous metastasis that causes lymphoedema and various eruptions. We report a case of lung cancer with CLC that caused both superior vena cava (SVC) stenosis and cervicofacial oedema, suggestive of SVC syndrome. A 64-year-old woman with lung adenocarcinoma presented with cervicofacial oedema and erythema, followed by severe dyspnoea 2 months after four cycles of carboplatin, pemetrexed and bevacizumab triplet therapy. Read More

Medicine (Baltimore) 2018 Apr;97(16):e0406

Department of Otorhinolaryngology, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, South Korea.

Rationale: Actinomycosis is a rare anaerobic, gram-positive bacterial infection caused by Actinomyces, which is part of the normal flora in the oral cavity and respiratory and female genitourinary tracts. The cervicofacial area is the most common site of involvement, and involvement of the central nervous system is rare.

Patient Concerns: We report a case involving a 51-year-old woman who developed an actinomycotic brain abscess 15 months after the treatment of noninvasive nasopharyngeal actinomycosis, which recurred as an invasive form. Read More

Anat Rec (Hoboken) 2018 Apr 16. Epub 2018 Apr 16.

Department of Human Anatomy and Embryology, Facultad de Medicina, Universidad Complutense de Madrid, Madrid, Spain.

Introduction: The extrapetrous course of the facial nerve has been a matter of study and debate since XIX century. Two different classifications have been classically proposed and widely accepted by most of the authors. Nevertheless, there are reported cases which do not fit in any of those. Read More

Zdr Varst 2018 Mar 5;57(1):17-24. Epub 2018 Jan 5.

University Clinical Center Ljubljana, Department for Otorhinolaryngology and Cervicofacial Surgery, Zaloska cesta 2,1000Ljubljana, Slovenia.

Introduction: The voice represents a basic working tool for carrying out certain occupations. Hoarseness, as a consequence of vocal fold lesions, presents an important cause of work-related absences for voice professionals.

Methods: Our study was designed as a retrospective cohort one. Read More

Int J Pediatr Otorhinolaryngol 2018 May 7;108:30-34. Epub 2018 Feb 7.

Department of Otolaryngology, Medical College of Wisconsin (MCW), Milwaukee, WI, United States. Electronic address:

Introduction: Extensive cervicofacial venous malformations (VM) pose significant challenges to a patient's quality of life (altered breathing, dysphagia, dysarthria). Treatment options include: 1) Surgical debulking; 2) Sclerotherapy; 3) laser therapy; or 4) Combined modalities. Recent studies have demonstrated the importance of multimodality and multidisciplinary management of these patients. Read More

J Contemp Dent Pract 2018 Mar 1;19(3):352-355. Epub 2018 Mar 1.

Department of Oral and Maxillofacial Surgery, College of Dentistry, University of Pernambuco, Camaragibe, Brazil.

Introduction: Odontogenic infections originate from a tooth or from its supporting structures, generally secondary to a pulp necrosis, periodontal disease, pericoronitis, apical lesions, or complications of dental procedures, which can be restricted to the alveolus or can reach the jaws and face through maxillofacial spaces. These are the most common conditions which affect the head and neck regions.

Aim: The aim of this study is to report a severe case of a cervicofacial odontogenic infection while discussing the most relevant aspects. Read More

Basic Clin Pharmacol Toxicol 2018 Sep 4;123(3):247-256. Epub 2018 May 4.

Department of Experimental Oncology, Institute of Oncology Ljubljana, Ljubljana, Slovenia.

Pre-clinical and clinical data indicate differences in the responses of melanoma and carcinoma tumours to electrochemotherapy. The purpose of this study was to investigate the origin of this difference, whether it is due to the intrinsic difference in tumour cell susceptibility to the chemotherapeutic, or due to the tumour micro-environment. For this purpose, we performed a pre-clinical study in B16F1 melanoma and TS/A carcinoma tumours in mice, in which the antitumour effectiveness of electrochemotherapy with bleomycin, the intrinsic sensitivity of tumour cells in vitro, the pharmacokinetics of bleomycin in plasma and tumours, and the vascularization of tumours in vivo were evaluated. Read More

J Craniofac Surg 2018 May;29(3):767-768

Department of Pathology, Soonchunhyang University Cheonan Hospital, Soonchunhyang University College of Medicine, Cheonan, Republic of Korea.

Dermoid cysts are benign developmental anomalies that occurred as a result of the sequestration of the skin along the lines of embryonic closure. Those occurring in the cervicofacial region are uncommon, accounting for about 7% of all dermoids and its presence in postauricular region is further exceptionally rare. A healthy 19-year-old Asian boy presented with a unilateral postauricular cyst that had been present since childhood without any symptom. Read More