53 results match your criteria Cervicofacial Lymphangiomas


New Treatment Option for Capillary Lymphangioma: Bleomycin-Based Electrochemotherapy of an Infant.

Pediatrics 2020 12;146(6)

Plastic Surgery Unit,

The treatment of microcystic and combined lymphangiomas, especially in the head and neck region, is still a challenge because the lymphangiomas do not respond to conventional therapies and their recurrence rate is high, regardless of the treatment choice. Complete surgical resection is the main treatment of lymphangiomas, but because of localization perioperative complications, such as bleeding, neural damage and airway obstruction are common disadvantages of this method. Bleomycin-based sclerotherapy is another common therapeutic approach, in which the lymphocysts are aspirated, and 25% to 50% of their volumes are replaced with a sclerotisant drug. Read More

View Article and Full-Text PDF
December 2020

Early Adjuvant Medication With the mTOR Inhibitor Sirolimus in a Preterm Neonate With Compressive Cystic Lymphatic Malformation.

Front Pediatr 2020 28;8:418. Epub 2020 Jul 28.

Service de Réanimation Néonatale, HFME, Hospices Civils de Lyon, Bron, France.

Cystic lymphatic malformations result from an abnormal embryological development of the lymphatic structures. Here we report on a case of a preterm female baby, born at 34 weeks of gestation, with a voluminous cervicofacial cystic lymphatic malformation responsible for an airway obstruction. An mTOR inhibitor, sirolimus, was started from the first day of life, and was combined with iterative sclerotherapy procedures. Read More

View Article and Full-Text PDF

[Retroperitoneal cystic lymphangioma treated by sildenafil].

Rev Med Liege 2020 Jul;75(7-8):541-543

Service de Chirurgie cardiovasculaire, CHU Liège, Belgique.

Cystic lymphangioma is a rare and benign lymphatic malformation found most often in the first two years of life. Clinical manifestations are diverse and depend on size and site of the lesion. The most frequently affected sites are cervicofacial and axillary areas. Read More

View Article and Full-Text PDF

Cystic lymphangioma in adult: a case report and a review of the literature.

J Surg Case Rep 2020 Jul 31;2020(7):rjaa179. Epub 2020 Jul 31.

U.O.S. Maxillofacial Surgery, S. Andrea Hospital, Rome, Italy.

Cystic lymphangioma (CL) in adult is a very rare pathology. Its etiology remains unclear, but it is supposed to be congenital or to be a result of obstruction and lymph fluid retention of developing lymphatic vessels. It generally occurs in the head and neck region, probably because of the rich lymphatics in this area. Read More

View Article and Full-Text PDF

The Management of Giant Cerviofacial Lymphatic Malformations in Children.

J Craniofac Surg 2019 Sep;30(6):e553-e555

Department of Otolaryngology-Head and Neck Surgery, Shanghai Children's Hospital, Shanghai Jiao Tong University.

Objective: Lymphatic malformations (LMs) are rare and benign diseases. This article aimed to present a series of surgically treated giant cervicofacial LMs in children.

Methods: A retrospective analysis of giant cervicofacial LMs (tumor diameter greater than 10 cm) in children over the past 8 years was performed in our department. Read More

View Article and Full-Text PDF
September 2019

Recurrent Neck Lymphangioma in a Young Adult: Twenty-Three Years After Successful Treatment.

Vasc Endovascular Surg 2019 Feb 29;53(2):170-176. Epub 2018 Nov 29.

4 ENT Clinic of Red Cross Hospital, Athens, Greece.

Lymphangiomas are rare benign malformations of the lymphatic system, commonly present in children, over the head and neck area. Occasionally, they can grow significantly in size and especially those located over the cervical region can cause airway obstruction and become life-threatening. Recurrent lymphangiomas usually occur during the early postsurgical period and 80% of them within the first 3 to 5 years. Read More

View Article and Full-Text PDF
February 2019

[The superficial circumscribed lymphangioma of the tongue].

Pan Afr Med J 2018 6;29:202. Epub 2018 Apr 6.

Service de Dermatologie, CHU Hassan II, Fes, Maroc.

Superficial circumscribed lymphangiomas are predominantly benign lesions occuring in the cervicofacial area. These malformations of the lymphatic vessels are frequently diagnosed in children. We report the clinical case of lymphangioma of the tongue that occurred in an old man. Read More

View Article and Full-Text PDF

[Unusual macrocystic lymphatic malformation in an adult patient].

Pan Afr Med J 2017 10;28:128. Epub 2017 Oct 10.

Service de Dermatologie-Vénéréologie, CHU Ibn Rochd, Université Hassan II, Casablanca, Maroc.

Macrocystic lymphatic malformations (MLMs) constitute a circumscribed variation in deep lymphangiomas. They are characterized by a rare occurrence in adults, by their rapid expansion and by their frequent occurrence at the level of the cervicofacial region (75%) and axillary region (20%). They rarely occur in lower limbs. Read More

View Article and Full-Text PDF

Cervicofacial Lymphatic Malformations: A Retrospective Review of 40 Cases.

Arch Plast Surg 2016 Jan 15;43(1):10-8. Epub 2016 Jan 15.

Department of Plastic and Reconstructive Surgery, Kyungpook National University School of Medicine, Daegu, Korea.

Background: Lymphatic malformation (LM) is a form of congenital vascular malformation with a low incidence. Although LM has been studied, no consensus has emerged regarding its cause or treatment.

Methods: In this study, we retrospectively evaluated 40 patients who visited our vascular anomalies center for the treatment of cervicofacial LM, which is a common manifestation of LM. Read More

View Article and Full-Text PDF
January 2016

Enlarging cystic lymphangioma of the mediastinum in an adult: is this a neoplastic lesion related to the recently discovered PIK3CA mutation?

Int J Clin Exp Pathol 2015 1;8(5):5924-8. Epub 2015 May 1.

Department of Pathology, Fujieda Municipal General Hospital Shizuoka, Japan.

Cystic lymphangioma, a lymphatic system malformation, is usually observed in infants and children and is rarely found in adults. It most commonly occurs in the cervicofacial region, followed by the axilla. Mediastinal cystic lymphangioma is rare, accounting for 1. Read More

View Article and Full-Text PDF

A review of the management of lymphangiomas.

Curr Pediatr Rev 2014 ;10(3):238-48

Princess Margaret Hospital, Roberts Road, Subiaco, Western Australia 6008, Australia.

Introduction: Lymphangioma is a rare benign cyst caused by congenital malformation of the lymphatic systems that often occurs in the cervicofacial region. There is no consensus on its management: Observation, aspiration, injection, cryotherapy, electrocautery, radiation, laser, ligation and excision.

Methods: We performed a literature search with the keywords "cystic hygroma", "lymphangioma", "management", "OK 432" and "picibanil" from Medline, Embase and PubMed databases. Read More

View Article and Full-Text PDF

Giant pediatric cervicofacial lymphatic malformations.

J Craniofac Surg 2013 Jul;24(4):1307-9

Department of Maxillofacial Surgery and ENT, Avicenne University Medical Center, Rabat, Morocco.

Purpose: Lymphatic malformations (LMs) are benign lesions. Most of them are found in head and neck regions as asymptomatic mass, but giant lymphangiomas may affect breathing or swallowing and constitute a major therapeutic challenge.

Methods: A retrospective analysis of giant head and neck LMs with impairment of respiration or swallow for the past 11 years was performed in the Department of Maxillofacial Surgery and ENT of the Avicenne Medical University Center. Read More

View Article and Full-Text PDF

Treatment of lymphangioma of the face with intralesional bleomycin: case discussion and literature review.

J Maxillofac Oral Surg 2011 Jun 20;10(2):152-4. Epub 2011 Apr 20.

Surgical treatment of lymphangioma of the face is a difficult task to achieve due to close vicinity of the lesion to the facial nerve and possibility of scar tissue formation. Inefficient surgical removals generally will give rise to high recurrence rates because of infiltrative and diffuse extension of the lesion. However, complete cure has been described by non-surgical methods. Read More

View Article and Full-Text PDF

Cervicofacial actinomycosis mimicking lymphangioma circumscriptum.

Indian J Dermatol 2011 May;56(3):321-3

Department of Dermatology, Venereology and Leprosy, Grant Medical College and Sir J J Group of Hospitals, Mumbai, India .

Primary cutaneous actinomycosis caused by Actinomyces israelii occurs most commonly in the cervicofacial area. It commonly presents as "lumpy jaw" with draining sinuses which discharge the characteristic "sulfur granules". A low index of suspicion and a low sensitivity in culturing the organism, due to its fastidious nature often delays the diagnosis. Read More

View Article and Full-Text PDF

An unusual presentation of a mesenteric lymphangioma.

J Indian Med Assoc 2010 Sep;108(9):606, 608

Department of Paediatric Medicine, NRS Medical College and Hospital, Kolkata 700014.

Lymphatic malformations are the second most common benign vascular tumour in children, after haemangioma. They may be localised or generalised and commonly occur in the cervicofacial region, axilla and thorax. They appear early in life with almost all cases evident by the age of 3 years. Read More

View Article and Full-Text PDF
September 2010

Surgical excision as primary treatment modality for extensive cervicofacial lymphatic malformations in children.

Int J Pediatr Otorhinolaryngol 2011 May 21;75(5):673-7. Epub 2011 Mar 21.

Department of Paediatric Otolaryngology, Great Ormond Street Hospital, Great Ormond Street, London, WC1N 3JH, United Kingdom.

Objective: There has been much recent focus on sclerotherapy treatment of lymphatic malformations with OK432. Surgical treatment however can have a number of advantages, including complete curative excision. The aim of this study was to evaluate the results of surgical excision as the primary (first) treatment for this condition. Read More

View Article and Full-Text PDF

[Congenital cyst and fistula of the face and neck].

Rev Laryngol Otol Rhinol (Bord) 2010 ;131(2):75-82

Hôtel-Dieu, Service d'O.R.L. et de Chirurgie Cervico-Faciale, Place A. Ricordeau, BP 1005, 44093 Nantes Cedex 01, France.

The authors propose an update on cervicofacial congenital cysts and fistulas' symptomatology. Embryological data, epidemiology and clinical manifestations are described. A reminder of the therapeutic principles is proposed as well as the evolution of these congenital pathologies, which may or may not involve the branchial system. Read More

View Article and Full-Text PDF

Sclerotherapy with bleomycin does not adversely affect facial nerve function in children with cervicofacial cystic lymphatic malformation.

J Pediatr Surg 2010 Aug;45(8):1627-32

Department of Pediatric Surgery, Hacettepe University Faculty of Medicine, Ankara 06100, Turkey.

Background And Purpose: Sclerotherapy with bleomycin sulfate (BS) is currently used in the management of cervicofacial cystic lymphatic malformations in children. Neurotoxic adverse effects of BS after intraventricular or intracavitary administration have been reported; however, the effects of intralesionally administered BS on the adjacent peripheral neural structures have not been previously investigated. The authors conducted a clinical experimental study to evaluate facial nerve function in children who have undergone BS sclerotherapy for cervicofacial cystic lymphatic malformation. Read More

View Article and Full-Text PDF

[Diagnosis and surgical treatment of cervical lymphangioma].

Zhonghua Yi Xue Za Zhi 2009 Dec;89(48):3413-6

Department of Otolaryngology, Qilu Hospital, Shandong University, Jinan 250012, China.

Objective: To discuss the methods of surgical treatment and their timing choices of cervical lymphangioma.

Methods: A retrospective review of 53 patients with cervicofacial lymphangioma were treated surgically from July 1990 to December 2008. The age at operation was from 6. Read More

View Article and Full-Text PDF
December 2009

Lymphatic malformations: a proposed management algorithm.

Int J Pediatr Otorhinolaryngol 2010 Apr 18;74(4):398-403. Epub 2010 Feb 18.

Our Lady's Hospital for Sick Children, Crumlin, Dublin, D12, Republic of Ireland.

Objective: The aim of this study was to develop a management algorithm for cervicofacial lymphatic malformations, based on the authors' experience in managing these lesions as well as current literature on the subject.

Study Design And Methods: A retrospective medical record review of all the patients treated for lymphatic malformations at our institution during a 10-year period (1998-2008) was performed.

Data Collected: age at diagnosis, location and type of lesion, radiologic investigation performed, presenting symptoms, treatment modality used, complications and results achieved. Read More

View Article and Full-Text PDF

Surgical excision of cervicofacial giant macrocystic lymphatic malformations in infants and children.

Int J Pediatr Otorhinolaryngol 2009 Jun 25;73(6):833-7. Epub 2009 Mar 25.

Department of Oral and Maxillofacil Surgery, China.

Objectives: Various modalities have been used to treat lymphatic malformations, such as steroids, the injection of sclerosing agents, aspiration, and surgery. Giant macrocystic lymphangiomas involving the cervicofacial region in infants and children constitute a major therapeutic challenge.

Methods: This was a retrospective review of 47 pediatric patients with giant macrocystic lymphatic malformations of the cervicofacial region that underwent surgical resections. Read More

View Article and Full-Text PDF

Massive lymphatic malformations of the head, neck, and chest.

J Otolaryngol Head Neck Surg 2008 Apr;37(2):169-73

Division of Pediatric Otolaryngology & Head/Neck Surgery, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229, USA.

Objective: To provide clinicians with an overview of the complications and functional and clinical outcomes of children affected by massive lymphatic malformations affecting multiple sites in the head, neck, and/or chest.

Methods: We reviewed the medical records of all patients who received treatment for massive cervicofacial lymphatic malformations at our tertiary care pediatric institution during a 17-year period. Massive lesions were defined as (1) unilateral lesions that infiltrated at least 50% of two anatomic regions, including the head, neck, or chest; (2) unilateral lesions in which there was involvement of the midline structures of the head or neck; or (3) bilateral lesions in which 50% of each side was affected. Read More

View Article and Full-Text PDF

[Cystic cervicofacial lymphangioma in children in Gabon].

Ann Otolaryngol Chir Cervicofac 2007 Dec;124(6):277-84

Service d'ORL et de chirurgie cervicofaciale, hôpital d'instruction des armées Omar-Bongo-Ondimba, BP 20404, Libreville, Gabon.

Objectives: To review the etiopathogenesis, diagnosis, and the role of surgery in the management of childhood cystic cervicofacial lymphangioma in Gabon.

Material And Methods: Our retrospective study concerned 16 cases of childhood cystic cervicofacial lymphangioma treated surgically between 1990 and 2004.

Results: The sample included ten girls and six boys whose average age was 30. Read More

View Article and Full-Text PDF
December 2007

[OK-432 therapy for cervicofacial lymphangioma in adults].

Acta Otorrinolaringol Esp 2007 May;58(5):222-4

Servicio de Cirugía Oral y Maxilofacial, Hospital del Río Hortega, Valladolid, España.

The treatment of cervicofacial lymphangiomas has been changing in recent years. OK-432 appears to be a relatively safe and effective treatment option for patients of all ages. An intracystic injection of OK-432 produces a local inflammatory reaction, leading to resolution of the lesion. Read More

View Article and Full-Text PDF

[State of the art of classification, diagnostics and therapy for cervicofacial hemangiomas and vascular malformations].

Laryngorhinootologie 2006 Dec;85(12):883-91

Klinik für Hals-Nasen- und Ohrenheilkunde der Philipps-Universität Marburg.

The successful treatment of vascular anomalies depends on profound knowledge of the biologic behavior of vascular lesions and their correct classification. On the base of the clinical course Mulliken and Glowacki developed a biologic classification that was accepted as official classification by the ISSVA (International Society for the Study of Vascular Anomalies). Based on an extended literature research, this manuscript will give an overview of different internationally accepted treatment concepts. Read More

View Article and Full-Text PDF
December 2006

[Management of lymphatic malformations in oral and maxillofacial regions: the rationale according to the new classification].

Shanghai Kou Qiang Yi Xue 2005 Dec;14(6):553-6

According to the classification of ISSVA, Waner and Suen, the traditionally called lymphangiomas are now referred to as lymphatic malformations, including both macrocystic and microcystic lesions. They are commonly seen vascular anomalies, and most frequently diagnosed at birth and most often occur in the head and neck area. The etiology of lymphatic malformations is still unknown, resulting in a variety of treatment modalities. Read More

View Article and Full-Text PDF
December 2005

Surgical treatment of cervicofacial cystic hygromas in children.

ORL J Otorhinolaryngol Relat Spec 2005 1;67(6):331-4. Epub 2005 Dec 1.

Department of Pediatric Surgery, Gazi University Medical Faculty, Emek, Turkey.

Aim: The aim of this study was to evaluate the results of surgical treatment of cervicofacial cystic hygromas in children.

Patients And Methods: Medical records of 17 patients who were operated for cervicofacial cystic hygroma between 1985 and 2004 were evaluated in terms of age, gender, symptoms, diagnostic workups, outcomes and complications.

Results: There was a slight male predominance -- 10 (59%) boys and 7 (41%) girls. Read More

View Article and Full-Text PDF

Altered pigment epithelium-derived factor and vascular endothelial growth factor levels in lymphangioma pathogenesis and clinical recurrence.

Arch Otolaryngol Head Neck Surg 2005 Nov;131(11):990-5

Department of Otolaryngology-Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, Ill, USA.

Objective: To determine the role of angiogenesis in the clinical behavior and pathogenesis of lymphangioma tumors.

Design: A retrospective study. Median follow-up period was 44. Read More

View Article and Full-Text PDF
November 2005

Intrapartum management of severe fetal airway obstruction.

J Otolaryngol 2004 Oct;33(5):283-8

Department of Pediatric Otolaryngology, 3333 Burnet Avenue, Cincinnati Children's Hospital Medical Center, Cincinnati, OH 45229-3039, USA.

Objective: To review our experience with the planned intrapartum management of fetuses with suspected severe airway obstruction.

Methods: Retrospective review of prenatal presentations, intrapartum airway procurement methods, outcomes, and complications.

Results: All cases (N = 11) at our tertiary airway referral institution between 1995 and 2002 were reviewed. Read More

View Article and Full-Text PDF
October 2004

Pediatric cervicofacial tissue expansion.

Int J Pediatr Otorhinolaryngol 2005 Nov;69(11):1509-13

University of California Irvine, Aesthetic and Plastic Surgery Institute, Irvine, CA, USA.

Introduction: Tissue expanders have long been used for reconstructing large cutaneous and fascio-cutaneous defects in children. Previous studies have examined tissue expansion for all body regions, touching upon the head and neck regions. We present a focused review of our experience with cervicofacial tissue expansion in the pediatric population. Read More

View Article and Full-Text PDF
November 2005