3,538 results match your criteria Cervicitis


A rare manifestation of CMV disease in a kidney transplant recipient.

Transpl Infect Dis 2020 Nov 25:e13527. Epub 2020 Nov 25.

Division of Infectious Diseases, Mayo Clinic, Rochester, MN, USA.

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November 2020

An Unusual Case of Extra-Enteric Blastocystosis in the Uterine Cervix.

Korean J Parasitol 2020 Oct 22;58(5):571-576. Epub 2020 Oct 22.

Hospital General "Dr. Manuel Gea Gonzalez", Mexico City 14080, Mexico.

Extra-enteric infections by Blastocystis spp. have rarely been documented. Here, we report a case of extra-enteric blastocystosis in a patient with minimal cervicitis symptoms. Read More

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October 2020

Photodetection and Safety of 5-Aminolevulinic Acid-Induced Porphyrin in Patients With Cervical Intraepithelial Neoplasia.

Lasers Surg Med 2021 Jul 8;53(5):654-663. Epub 2020 Nov 8.

Department of Obstetrics and Gynecology, Peking University First Hospital, Beijing, 100034, China.

Background And Objectives: 5-Aminolevulinic acid (5-ALA) is a porphyrin-based photosensitizer and has been used for photodynamic therapy of cervical intraepithelial neoplasia (CIN). In this study, photodetection and safety of 5-ALA-induced porphyrin in CIN tissues were assessed.

Study Design/materials And Methods: A total of 42 patients for whom colposcopy or loop electrosurgical excision procedure (LEEP) was planned were administered 10%, 20%, or 30% 5-ALA locally on the surface of the cervix for 1. Read More

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Alternative conformation of the C-domain of the P140 protein from Mycoplasma genitalium.

Acta Crystallogr F Struct Biol Commun 2020 Nov 8;76(Pt 11):508-516. Epub 2020 Oct 8.

Department of Structural Biology, Institut de Biologia Molecular de Barcelona (IBMB-CSIC), Parc Científic de Barcelona, Baldiri Reixac 10-12, 08028 Barcelona, Spain.

The human pathogen Mycoplasma genitalium is responsible for urethritis in men, and for cervicitis and pelvic inflammatory disease in women. The adherence of M. genitalium to host target epithelial cells is mediated through an adhesion complex called Nap, which is essential for infectivity. Read More

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November 2020

Liquid-based cytology of amoebic cervicitis clinically mimicking cervical cancer.

Diagn Cytopathol 2021 Mar 31;49(3):433-435. Epub 2020 Oct 31.

Department of Cytopathology, Sir Ganga Ram Hospital, New Delhi, India.

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A profile of the FDA-approved and CE/IVD-marked Aptima assay (Hologic) and key priorities in the management of infections.

Expert Rev Mol Diagn 2020 11 2;20(11):1063-1074. Epub 2020 Nov 2.

WHO Collaborating Centre for Gonorrhoea and Other STIs, Department of Laboratory Medicine, Faculty of Medicine and Health, Örebro University , Örebro, Sweden.

Introduction: (MG) causes frequently asymptomatic STIs. MG prevalence figures are lacking and management is complicated by the lack of etiological diagnostics and high antimicrobial resistance in many countries. Appropriately validated, quality-assured, and FDA-approved MG diagnostic assays have been lacking. Read More

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November 2020

The impact of cryotherapy for symptomatic cervical ectropion on female sexual function and quality of life.

J Obstet Gynaecol 2020 Oct 19:1-6. Epub 2020 Oct 19.

Department of Obstetrics and Gynecology, Faculty of Medicine, Istanbul Aydın University, Istanbul, Turkey.

In rare cases, cervical ectropion causes symptoms such as abundant leucorrhoea, postcoital bleeding, recurrent cervicitis, pelvic pain, and dyspareunia. Cryotherapy is a commonly used treatment for symptomatic cervical ectropion. We assessed the impact of cryotherapy on sexual function and quality of life among patients with symptomatic cervical ectropion. Read More

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October 2020

Single-Inclusion Kinetics of Development.

mSystems 2020 Oct 13;5(5). Epub 2020 Oct 13.

Department of Biological Sciences, University of Idaho, Moscow, Idaho, USA

The obligate intracellular bacterial pathogen is reliant on a developmental cycle consisting of two cell forms, termed the elementary body (EB) and the reticulate body (RB). The EB is infectious and utilizes a type III secretion system and preformed effector proteins during invasion, but it does not replicate. The RB replicates in the host cell but is noninfectious. Read More

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October 2020

Prevalence of Chlamydia trachomatis in an asymptomatic female population attending cervical cytology services of three healthcare centers in Medellín, Colombia

Biomedica 2020 09 1;40(3):534-545. Epub 2020 Sep 1.

Grupo de Bacterias y Cáncer, Universidad de Antioquia, Medellín, Colombia.

Introduction: The sexually transmitted infection caused by Chlamydia trachomatis is the most common of bacterial etiology in the world. Although it can be asymptomatic in most cases, it can produce several reproductive health problems in women such as cervicitis, endometritis, and salpingitis. Despite its importance, the epidemiological data on this infection is insufficient in Medellín. Read More

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September 2020

Correlation between multi-type human papillomavirus infections and viral loads and the cervical pathological grade.

Int J Gynaecol Obstet 2021 Jan 22;152(1):96-102. Epub 2020 Oct 22.

Department of Clinical Laboratory, Shanxi Provincial People's Hospital, Affiliated to Shanxi Medical University, Taiyuan, Shanxi, China.

Objective: To investigate the relationship between single/multiple HPV infections and cervical lesions, and the correlation between viral load and the degree of cervical lesions.

Methods: A total of 27 284 patients who underwent testing for HPV were retrospectively screened and 3728 women were enrolled who tested positive for HPV when examined by liquid-based ThinPrep cervical smear cytology test and diagnosed by histopathology at the Shanxi Provincial People's Hospital between May 2017 and March 2019. The genotype and viral load of HPV were determined by fluorescence quantitative polymerase chain reaction. Read More

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January 2021

Sexually Transmitted Infections Part 2: Discharge Syndromes and Pelvic Inflammatory Disease.

Pediatr Rev 2020 Oct;41(10):522-537

Division of Adolescent and Young Adult Medicine and.

Sexually transmitted infections (STIs) disproportionately affect young people, with more than half of the infections occurring in youth aged 15 to 25 years. (1)(2) This review, the second in a 2-part series on STIs, focuses on infections that may cause abnormal vaginal or penile discharge, including trichomonas, chlamydia, gonorrhea, and pelvic inflammatory disease (PID). Most infected persons, however, are asymptomatic. Read More

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October 2020

Co-infection between genotypes of the human papillomavirus and in Mexican women.

Int J STD AIDS 2020 11 30;31(13):1255-1262. Epub 2020 Sep 30.

Laboratorio de Virología, Departamento de Infectología del Instituto Nacional de Perinatología Isidro Espinosa de los Reyes, Colonia Lomas de los Virreyes, Delegación Miguel Hidalgo, Ciudad de México, Mexico.

Not all human papillomavirus (HPV) infections develop into cervical cancer (CC), so it is proposed that other factors may influence this, such as co-infection with (CT). To identify the prevalence of co-infection, we included 189 women with suspicion of HPV. Viral typing was performed by carrying out the Roche HP Linear Array test, while CT detection was performed with the COBAS® TaqMan® 48 kit from Roche. Read More

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November 2020

Assessment of p16 and Ki67 Immunohistochemistry Expression in Squamous Intraepithelial Lesion with Cytohistomorphological Correlation.

Iran J Pathol 2020 16;15(4):268-273. Epub 2020 Jul 16.

Department of Pathology, Kasturba Medical College, Mangalore, India.

Background & Objective: Cervical cancer is the most common cancer in women worldwide with high mortality, necessitating quicker diagnostic methods. We wish to enhance the existing cervical biopsies of Squamous Intraepithelial Lesions (SIL) using p16 and Ki67 as surrogate markers to assess correlation between its positivity and histological grade of the lesion.

Methods: Analysis of p16 and Ki67 expression was done on 31 histopathologically diagnosed cases of SILs. Read More

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Retrospective Review of Loop Electrosurgical Excision Procedure (LEEP) Outcomes at a Tertiary Hospital in Zambia.

Obstet Gynecol Int 2020 19;2020:1920218. Epub 2020 Aug 19.

Department of Obstetrics and Gynecology, Ndola Teaching Hospital, Ndola 10101, Zambia.

There is a lack of knowledge on the histologic outcomes of loop electrosurgical excision procedure (LEEP) biopsies in the diagnosis, treatment, and prevention of cervical cancer in Zambia. This study determined the outcomes of LEEP biopsies and associated factors at a tertiary hospital. We conducted a retrospective chart review of patients evaluated at a tertiary hospital cervical cancer screening centre. Read More

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Neutrophil interactions with the sexually transmitted parasite implications for immunity and pathogenesis.

Open Biol 2020 09 2;10(9):200192. Epub 2020 Sep 2.

Department of Biological Sciences, California State Polytechnic University, Pomona, CA, USA.

Trichomoniasis is the third most common sexually transmitted infection in humans and is caused by the protozoan parasite, (). Pathogenic outcomes are more common in women and generally include mild vaginitis or cervicitis. However, more serious effects associated with trichomoniasis include adverse reproductive outcomes. Read More

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September 2020

The role of diet and probiotics in prevention and treatment of bacterial vaginosis and vulvovaginal candidiasis in adolescent girls and non-pregnant women.

Ginekol Pol 2020;91(7):412-416

Department of Perinatology and Gynecology, Gynecology Clinic, Poznan University of Medical Sciences, Poland.

The article raises important issues regarding the use of diet and probiotics in prevention and treatment of vaginitis. Vaginitis is defined as any condition with symptoms of abnormal vaginal discharge. The most common causes of vaginitis are vulvovaginal candidiasis (VVC), trichomoniasis and bacterial vaginosis (BV). Read More

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January 2020

Cervical Cytology of Samples with , , , , , and Detected by Multiplex PCR.

Biomed Res Int 2020 7;2020:7045217. Epub 2020 Jul 7.

Pathology Department of Brasília University, Brasília, Federal District, Brazil.

Introduction: Despite increasing application of molecular diagnostic methods for the detection of sexually transmitted infections, the cytological findings in pap smears of patients with pathogens that can be identified only by PCR are not yet well described. The aim of this study was to describe the most common cytological features in cervical pap smears of patients with , , , , , , and detected by multiplex PCR.

Methods: Cervical samples for conventional and liquid-based cytology and for multiplex PCR were collected from women ranging from 23 to 54 years old, who underwent routine screening at a gynecological Unit. Read More

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Association between APOBEC3s and HPV16 E2 gene hypermutation in Uygur females with cervical cancer.

Oncol Lett 2020 Aug 5;20(2):1752-1760. Epub 2020 Jun 5.

Department of Obstetrics and Gynecology, People's Hospital of Xinjiang Uygur Autonomous Region, Urumqi, Xinjiang Uygur Autonomous Region 830001, P.R. China.

The present study aimed to investigate whether apolipoprotein B mRNA-editing enzyme catalytic polypeptides (A3) are involved in the regulation of cervical cancer development and human papilloma virus (HPV)16 sustained infection in Uighur females. Cervical tissues of Uygur patients with HPV16 with cervical lesions were collected. Expression levels of A3C, A3F and A3G were detected using reverse transcription-quantitative PCR and western blotting. Read More

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An effective UFLC-MS/MS method used to study pharmacokinetics of major constituents of Fukeqianjin formula in rat plasma.

Chin Med 2020 25;15:74. Epub 2020 Jul 25.

Zhuzhou Qianjin Pharmaceutical Co., Ltd, Zhuzhou, 412000 China.

Background: Fukeqianjin formula (FKQJF) is a Chinese medicine prescription, which has been widely used individually or in combination with other western medicine for the treatment of various gynecological inflammatory diseases, including chronic cervicitis, chronic pelvic inflammatory disease and endometritis, so on and so force.

Methods: The ultra-fast liquid chromatography coupled with triple quadrupole tandem mass spectrometry (UFLC-MS/MS), a quick and efficient method was established and applied to quantify the major constituents of Fukeqianjin formula in rat plasma, and its pharmacokinetics of oral absorption was studied. Nineteen components in Fukeqianjin formula were detected and identified as the major compounds absorbed into the blood according to their chromatographic behavior, molecular weight, ion fragments and other information of these compounds. Read More

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Streptococcus agalactiae-Induced Soft Tissue Infection in a Nonpregnant Adult After a Gynecological Procedure.

Am J Case Rep 2020 Jul 18;21:e924110. Epub 2020 Jul 18.

Department of Medicine, Anne Arundel Medical Center, Annapolis, MD, USA.

BACKGROUND We present a case of a 24-year-old woman with type 1- diabetes mellitus who developed necrotizing fasciitis (NF) due to Streptococcus agalactiae after a recent colposcopy. Literature review suggests this as the first case to be reported. CASE REPORT The patient initially presented to the emergency department (ED) with right lower neck pain and spasm of the right sternocleidomastoid muscle (SCM), with decreased range of motion. Read More

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Role of molecular biomarker human papilloma virus (HPV) E6 oncoprotein in cervical cancer screening.

Gynecol Oncol 2020 09 14;158(3):590-596. Epub 2020 Jul 14.

Massachusetts General Hospital, USA. Electronic address:

Objective: The Onco E6™ Cervical Test, based on detection of the E6 oncoprotein of HPV 16 and 18 genotypes is evaluated as a screen for the early detection cervical neoplasia in resource-limited countries.

Methods: This prospective study from June 2018 to June 2019 evaluated 235 women aged 21-65 years, who came to Gynaecological Oncology Outpatient Department by VIA, cytology, E6 oncoprotein test and by colposcopy. Screen-positive women by any of the tests or women with suspicious findings were further evaluated by biopsy at colposcopy. Read More

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September 2020

Epithelial Haven and Autophagy Breakout in Gonococci Infection.

Front Cell Dev Biol 2020 9;8:439. Epub 2020 Jun 9.

Departamento de Genética, Ecologia e Evolução, Instituto de Ciencias Biológicas, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.

The World Health Organization (WHO) has estimated that in 2016, there were 87 million new cases of gonorrhea. Gonorrhea is caused by the sexually transmitted human-exclusive agent , a Gram-negative diplococcus that causes cervicitis in females and urethritis in males and may lead to more severe complications. Currently, there is no vaccine against . Read More

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Associations between the expression of SCCA, MTA1, P16, Ki-67 and the infection of high-risk HPV in cervical lesions.

Oncol Lett 2020 Jul 18;20(1):884-892. Epub 2020 May 18.

Department of Obstetrics and Gynecology, North China University of Science and Technology Affiliated Hospital, Tangshan, Hebei 063000, P.R. China.

The application of detection technologies for human papillomavirus (HPV) has increased the resection rate for cervical intraepithelial neoplasia and early cervical cancer types. However, a large number of patients still present with advanced cervical cancer upon diagnosis. Therefore, to find a marker for the early diagnosis of cervical cancer, the present study investigated the expression profiles of squamous cell carcinoma antigen (SCCA), tumor metastasis related factor-1 (MTA1), the multiple tumor suppressor gene P16, and the nucleus-associated antigen Ki-67 in cervical lesions, and evaluated the association between the four proteins and the infection of high-risk (HR)-HPV in cervical lesions. Read More

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Brucellar reproductive system injury: A retrospective study of 22 cases and review of the literature.

J Int Med Res 2020 Jun;48(6):300060520924548

Department of Infection Disease Center, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, China.

Objective: We aimed to describe the clinical characteristics and prognosis of 22 patients with -induced reproductive system injury.

Methods: We assessed 22 patients with reproductive system injury between 2010 and 2018 at The First Affiliated Hospital of Xinjiang Medical University.

Results: The disease is predominant in men. Read More

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Formulation, Physiochemical, and Microbial Assay of Henna Oil Vaginal Suppository Formulated with Polyethylene Glycol Bases.

Iran J Med Sci 2020 May;45(3):207-213

Department of Pharmacology, School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.

Background: Persian Medicine is one of the oldest and richest complementary and alternative options in the field of medicine and has a comprehensive medical system. Henna oil is recommended in Persian Medicine for the treatment of numerous women's diseases such as cervicitis. To date, henna has been used for many medical purposes, including astringent, bleeding, cardioinhibitory, hypotension, and relaxation. Read More

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Meningococcal disease and sexual transmission: urogenital and anorectal infections and invasive disease due to Neisseria meningitidis.

Lancet 2020 06;395(10240):1865-1877

Immunisation and Countermeasures Division, Public Health England, London, UK.

Neisseria meningitidis is an obligate human commensal bacterium that frequently colonises the upper respiratory tract. Person-to-person transmission occurs via direct contact or through dispersion of respiratory droplets from a carrier of the bacteria, and can lead to invasive meningococcal disease. Rare sporadic cases of meningococcal urogenital and anorectal infections, including urethritis, proctitis, and cervicitis, have been reported, typically following orogenital contact with an oropharyngeal meningococcal carrier. Read More

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The application value of PAX1 and ZNF582 gene methylation in high grade intraepithelial lesion and cervical cancer.

Clin Transl Oncol 2021 Feb 8;23(2):283-288. Epub 2020 Jun 8.

Xuzhou Maternity and Child Health Care Hospital, No. 46 Heping Road, Xuzhou, 221009, People's Republic of China.

Purpose: To investigate the possibility of using the methylation level of PAX1/ZNF582 gene as molecular marker to differentiate the progression of cervical cancer.

Methods: From January 2016 to March 2018, 150 patients, who were admitted to Cervical Disease Diagnosis and Treatment Center of Xuzhu Maternity and Child Care Hospital, were enrolled in this study. Patients were classified into chronic cervicitis (for 19 cases), low-grade squamous intraepithelial lesion (LSIL) (18 cases), high-grade squamous intraepithelial lesion (HSIL) (37 cases) and squamous cell carcinoma (SCC) (31 cases). Read More

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February 2021