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Indian J Radiol Imaging 2019 Jan-Mar;29(1):61-66

Department of Radiodiagnosis, Tata Memorial Hospital, Mumbai, Maharashtra, India.

Context: Radiologists as a group face unique occupational health hazards among which musculoskeletal injuries, chronic eye strain, and others are yet to receive adequate attention. Constant mental strain due to demanding turnaround times and work pressures may lead to burnout and depression. These combine to decrease overall work satisfaction and productivity. Read More

Nucleosides Nucleotides Nucleic Acids 2019 Apr 16:1-19. Epub 2019 Apr 16.

a Saint Petersburg State University , 7/9 Universitetskaya nab., Saint Petersburg , 199034 , Russia.

3'-Azidothymidine (AZT) reacts with 1-propargyl-5-R-1H- and 2-propargyl-5-R-2H-tetrazoles (R = H, Me, CHCOOEt, CHCON(CH), Ph, 2-CH-CH, or 4-NO-CH) via the Cu(I)-catalyzed asymmetric [3 + 2] cycloaddition to give 3'-modified thymidine analogs incorporating 1H-1,2,3-triazolyl, 1H-, and 2H-tetrazolyl fragments in 41-76% yield. The structures of the obtained compounds have been elucidated by means of HRESI-MS, H and C{H} NMR, and single crystal X-ray diffraction {for 3'-[4-(1H-5-N,N-dimethylaminocarbonylmethyltetrazol-1-yl)-1H-1,2,3-triazol-1-yl]thymidine 10d}. In vitro biological evaluation of the prepared compounds has been performed; they have exhibited low activity against phenotypic HIV-1. Read More

Proc Natl Acad Sci U S A 2019 Apr 12. Epub 2019 Apr 12.

Department of Chemical Engineering, University of Illinois at Chicago, Chicago, IL 60607

Delayed capillary break-up of viscoelastic filaments presents scientific and technical challenges relevant for drop formation, dispensing, and adhesion in industrial and biological applications. The flow kinematics are primarily dictated by the viscoelastic stresses contributed by the polymers that are stretched and oriented in a strong extensional flow field resulting from the streamwise gradients created by the capillarity-driven squeeze flow. After an initial inertiocapillary (IC) or viscocapillary (VC) regime, where elastic effects seem to play no role, the interplay of capillarity and viscoelasticity can lead to an elastocapillary (EC) response characterized by exponentially-slow thinning of neck radius (extensional relaxation time is determined from the delay constant). Read More

Ear Nose Throat J 2019 Apr 8:145561319840830. Epub 2019 Apr 8.

1 Laboratory of Anatomy and Cell Biology, Faculty of Medicine, UMONS Research Institute for Health Sciences and Technology, University of Mons (UMons), Mons, Belgium.

Laryngopharyngeal reflux (LPR) is an inflammatory condition suspected to be associated with dysphonia. In this study, we investigated multidimensional perceptual, aerodynamic, and acoustic voice changes in patients with clinically diagnosed LPR compared to healthy participants. We prospectively included 80 outpatients with Reflux Finding Score (RFS) >7 and Reflux Symptom Index (RSI) >13 from September 2013 to April 2016 and we compared clinical and voice quality assessments of these patients with 80 healthy participants. Read More

Clin Exp Otorhinolaryngol 2019 Apr 9. Epub 2019 Apr 9.

Department of Otolaryngology-Head and Neck Surgery, Chonbuk National University-Chonbuk National University Hospital, Jeonju, Korea.

Objectives: Laser surgery (LS) or radiotherapy (RT) is normally recommended in early glottic cancer. The objective of this study was to perform a comprehensive meta-analysis of acoustic and perceptual outcomes to compare voice quality of LS or RT in early-stage glottic cancer.

Methods: Data sources were obtained after searching PubMed, Google Scholar, EBSCO, and RISS using the following search terms: glottic cancer, glottic carcinoma, endoscopic surgery, laser surgery, radiotherapy, radiation, voice, voice quality, and grade, roughness, breathiness, asthenia, and strain (GRBAS) scale. Read More

J Nat Prod 2019 Apr 8. Epub 2019 Apr 8.

Natural Products Research Institute , Korea Institute of Science and Technology (KIST) , 679 Saimdang-ro , Gangneung 25451 , Republic of Korea.

The total synthesis of nocarbenzoxazoles F (1) and G (2), originally obtained from the marine-derived halophilic bacterial strain Nocardiopsis lucentensis DSM 44048, was achieved via a simple and versatile route involving microwave-assisted construction of a benzoxazole skeleton, followed by carbon-carbon bond formation with the corresponding aryl bromides. Unfortunately, the H and C NMR spectra of natural nocarbenzoxazole G did not agree with those of the synthesized compound. In particular, the spectra of the isolated and synthesized compounds showed considerable differences in the signals from the protons and carbons in the aryl group. Read More

Int Urogynecol J 2019 Apr 6. Epub 2019 Apr 6.

Research Unit EA7285, Risk and Safety in Clinical Medicine for Women and Perinatal Health, Université Versailles St-Quentin, Montigny-le-Bretonneux, France.

Introduction And Hypothesis: Ultrasound measurement of urethral mobility is an attractive approach to directly visualize bladder neck descent (BND) during stress. BND assessed by transperineal ultrasound appears to be associated with stress urinary incontinence (SUI) severity. This study evaluated the inter- and intra-observer reliability of ultrasound BND measurement and its correlation with clinical examination. Read More

J Mater Sci Mater Med 2019 Apr 5;30(4):46. Epub 2019 Apr 5.

Ramsay Générale de Santé, Hôpital privé Le Bois, 59000, Lille, France.

Degeneration of the intervertebral disc (IVD) is a leading source of chronic low back pain or neck pain, and represents the main cause of long-term disability worldwide. In the aim to relieve pain, total disc replacement (TDR) is a valuable surgical treatment option, but the expected benefit strongly depends on the prosthesis itself. The present contribution is focused on the synthetic mimic of the native IVD in the aim to optimally restore its functional anatomy and biomechanics, and especially its time-dependency. Read More

Virol J 2019 03 29;16(1):40. Epub 2019 Mar 29.

WHO WPRO Regional Polio Reference Laboratory and NHC Key Laboratory of Biosafety, National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, People's Republic of China.

Background: Enterovirus C96 (EV-C96) is a newly named type of enterovirus belonging to species C, and the prototype strain (BAN00-10488) was firstly isolated in 2000 from a stool specimen of a patient with acute flaccid paralysis in Bangladesh. In this study, we report the genomic and phenotypic characteristics of two EV-C96 strains isolated from individuals from the Tibet Autonomous Region of China.

Methods: Human rhabdomyosarcoma (RD), human laryngeal epidermoid carcinoma (HEp-2), and human cervical cancer (Hela) cells were infected with the Tibet EV-C96 strains, and enterovirus RNA in the cell culture was detected with a real time RT-PCR-based enterovirus screening method. Read More

Clinics (Sao Paulo) 2019 03 25;74:e852. Epub 2019 Mar 25.

Departamento de Odontologia, Universidade de Passo Fundo, Passo Fundo, RS, BR.

Objectives: To evaluate and compare the magnitude and distribution of stresses generated on implants, abutments and first molar metal-ceramic crowns using finite element analysis.

Methods: Preliminary three-dimensional models were created using the computer-aided design software SolidWorks. Stress and strain values were observed for two distinct virtual models: model 1 - Morse taper and solid abutment; model 2 - Morse taper and abutment with screw. Read More

Ultraschall Med 2019 Mar 25. Epub 2019 Mar 25.

Department of Obstetrics and Gynecology, University-Hospital Münster, Germany.

Purpose:  To evaluate cervical elastography strain pattern as a predictive marker for spontaneous preterm delivery (SPTD).

Materials And Methods:  In this case-control study cervical length (CL) and elastographic data (strain ratio, elastography index, strain pattern score) were acquired from 335 pregnant women (20th - 34th week of gestation) by transvaginal ultrasound. Data of 50 preterm deliveries were compared with 285 normal controls. Read More

J Neurosurg Spine 2019 03 22:1-7. Epub 2019 Mar 22.

Department of Biomedical Engineering, The University of Iowa, and.

OBJECTIVE: Cervical myelopathy (CM) is a common and debilitating form of spinal cord injury caused by chronic compression; however, little is known about the in vivo mechanics of the healthy spinal cord during motion and how these mechanics are altered in CM. The authors sought to measure 3D in vivo spinal cord displacement and strain fields from MR images obtained during physiological motion of healthy individuals and cervical myelopathic patients. METHODS: Nineteen study participants, 9 healthy controls and 10 CM patients, were enrolled in the study. Read More

Mil Med 2019 03;184(Suppl 1):181-194

Multifunctional Materials Branch, Materials Science and Technology Division, U.S. Naval Research Laboratory, 4555 Overlook Ave. SW., Washington, DC.

Traumatic brain injury analysis in human is exceedingly difficult due to the methods in which data can be collected, thus many researchers commonly implement animal surrogates. However, use of these surrogates is costly and restricted by ethical concerns and test logistics. Computational models and simulations do not have these constraints and can produce significant amounts of data in relatively short periods. Read More

Mil Med 2019 03;184(Suppl 1):237-244

Medical College of Wisconsin, Department of Neurosurgery, 8701 W Watertown Plank Road, Milwaukee, WI.

Blunt impact assessment of the Advanced Combat Helmet (ACH) is currently based on the linear head response. The current study presents a methodology for testing the ACH under complex loading that generates linear and rotational head motion. Experiments were performed on a guided, free-fall drop tower using an instrumented National Operating Committee for Standards on Athletic Equipment (NOCSAE) head attached to a Hybrid III (HIII) or EuroSID-2 (ES-2) dummy neck and carriage. Read More

Emerg Med Australas 2019 Mar 20. Epub 2019 Mar 20.

RECOVER Injury Research Centre, The University of Queensland, Brisbane, Queensland, Australia.

Objective: To describe clinical presentation and management of neck soft tissue injury in an Australian ED.

Methods: This is a retrospective cohort study conducted in a tertiary hospital ED in Queensland, Australia. This study included all patients aged 18-65 years presenting with neck sprain/strain in 2016. Read More

J Med Life 2018 Oct-Dec;11(4):328-333

Neuroscience Research Center, Kerman University of Medical Sciences, Kerman, Iran.

This study aimed to identify the prevalence of musculoskeletal disorders (MSDs) and ergonomic risks for Kerman University of Medical Sciences' office workers. The study sample comprised all office workers in the University and the sample included 129 women and 121 men. Data on MSDs were derived from the Nordic Musculoskeletal Questionnaire, while ergonomic data were collected through two direct observations via the rapid upper limb assessment (RULA) and the rapid office strain assessment (ROSA) method. Read More

Laryngoscope 2019 Mar 19. Epub 2019 Mar 19.

Department of Neurology, Jose R. Reyes Memorial Medical Center, Manila, Philippines.

Objectives: To systematically characterize and describe voice and swallowing manifestations in patients with X-linked dystonia parkinsonism (XDP) and correlate with quality-of-life (QOL) measures.

Methods: Thirty-four patients with XDP with communication and swallowing difficulties underwent neurological examination, head and neck examination, nasopharyngoscopy, QOL surveys (Swallowing Quality of Life questionnaire [SWAL-QOL] and Voice Handicap Index [VHI]), and functional endoscopic evaluation of swallowing (FEES) to assess the extent of dysfunction.

Results: All patients showed high rates of lingual, oromandibular, and laryngeal dysfunction, as well as severe QOL changes in swallowing and communication ability. Read More

J Voice 2019 Mar 14. Epub 2019 Mar 14.

Departments of Otolaryngology-Head and Neck Surgery, Wake Forest School of Medicine, Winston-Salem, North Carolina. Electronic address:

Objective: To determine the effects of globus pallidus interna (GPi) deep brain stimulation (DBS) on speech and voice quality of patients with primary, medically refractory dystonia.

Methods: Voices of 14 patients aged ≥18years (males = 7 and females = 7) with primary dystonia (DYT1 gene mutation dystonia = 4, cervical dystonia = 6, and generalized dystonia = 4) with bilateral GPi DBS were assessed. Five blinded raters (two fellowship-trained laryngologists and three speech/language pathologists) evaluated audio recordings of each patient pre- and post-DBS. Read More

J Bone Miner Res 2019 Mar 13. Epub 2019 Mar 13.

Department of Materials Science and Engineering, Cornell University, Ithaca, NY.

People with type 2 diabetes mellitus (T2DM) have normal to high bone mineral densities, but, counterintuitively, have greater fracture risks than people without T2DM, even after accounting for potential confounders like BMI and falls. Therefore, T2DM may alter aspects of bone quality, including material properties or microarchitecture, that increase fragility independently of bone mass. Our objective was to elucidate the factors that influence fragility in T2DM by comparing the material properties, microarchitecture, and mechanical performance of cancellous bone in a clinical population of men with and without T2DM. Read More

J Korean Med Sci 2019 Mar 27;34(9):e68. Epub 2019 Feb 27.

Department of Obstetrics and Gynecology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea.

Background: We investigated whether there is a difference in elastographic parameters between pregnancies with and without spontaneous preterm delivery (sPTD) in women with a short cervix (≤ 25 mm), and examined the ability of elastographic parameters to predict sPTD in those women.

Methods: E-Cervix (WS80A; Samsung Medison, Seoul, Korea) elastography was used to examine the cervical strain. Elastographic parameters were compared between pregnancies with and without sPTD. Read More

Materials (Basel) 2019 Mar 11;12(5). Epub 2019 Mar 11.

Key Lab of Disaster Prevent and Structural Safety, Guangxi Key Lab Disaster Prevent and Engineering Safety, College of Civil Engineering and Architecture, Guangxi University, Nanning 530004, China.

After pre-fatigue cycles at different strain amplitudes with different values (33.3%, 50%, and 75%), specimens of HRB335 steel were subjected to uniaxial tension until failure. By this method the mechanical properties of the specimens after pre-fatigue testing were measured, and the fracture morphology and microscopic morphology in the vicinity of the specimen's neck surface near the fracture were observed. Read More

Immune Netw 2019 Feb 1;19(1):e7. Epub 2019 Feb 1.

Laboratory of Autoimmunology, Department of Anatomy and Cell Biology, Hanyang University College of Medicine, Seoul 04763, Korea.

Sjögren's syndrome (SS) is a chronic inflammatory autoimmune disorder that affects mainly salivary and lacrimal glands, but its cause remains largely unknown. Clinical data indicating that SS occurs in a substantial proportion of patients with lupus points to common pathogenic mechanisms underlying the two diseases. To address this idea, we asked whether SS develops in the lupus-prone mouse strain sanroque (SAN). Read More

Front Microbiol 2019 19;10:267. Epub 2019 Feb 19.

Floral and Nursery Plants Research Unit, United States National Arboretum, United States Department of Agriculture-Agricultural Research Service, Beltsville, MD, United States.

The first -infecting bacteriophage from soil of the United States, designated RsoM1USA, was isolated from a tomato field in Florida. Electron microscopy revealed that phage RsoM1USA is member of the genus in the family with an icosahedral head of about 66 nm in diameter, a contractile tail of about 152 nm in length, and a long "neck." Phage RsoM1USA infected 12 of the 30 tested species complex strains collected worldwide in each of the three species: , , and . Read More

Sci Rep 2019 Mar 5;9(1):3471. Epub 2019 Mar 5.

Dyson School of Design Engineering, Imperial College London, South Kensington Campus, London, SW7 2AZ, UK.

Traumatic brain injury (TBI) affects millions of people worldwide with significant personal and social consequences. New materials and methods offer opportunities for improving designs of TBI prevention systems, such as helmets. We combined empirical impact tests and computational modelling to test the effectiveness of new viscoelastic add-on components in decreasing biomechanical forces within the brain during helmeted head impacts. Read More

J Biosci 2019 Mar;44(1)

Applied Molecular Biology Laboratory, School of Life Sciences, Jawaharlal Nehru University, New Delhi 110 067, India.

Measles virus is the causative agent of measles, a major cause of child mortality in developing countries. Two major proteins, coded by the viral genome, are nucleocapsid protein (N) and phosphoprotein (P). The N protein protects the viral genomic RNA and forms ribonucleoprotein complex (RNP) together with P protein. Read More

Clin Biomech (Bristol, Avon) 2019 Mar 23;63:48-53. Epub 2019 Feb 23.

Department of Mechanical Engineering, University of Manitoba, Winnipeg, Canada.

Background: Clinicians have been looking for a simple and effective biomechanical tool for the assessment of hip fracture risk. Dual-energy X-ray absorptiometry (DXA) is currently the primary bone imaging modality in clinic, and the engineering beam is the simplest model for a mechanical analysis. Therefore, we developed a DXA-based beam model for the above purpose. Read More

Poult Sci 2019 Feb 28. Epub 2019 Feb 28.

Department of Poultry Science and Small Farm Animals, Faculty of Agrobiology and Food Resources, Slovak University of Agriculture, Nitra, Slovak Republic.

The aim of the study was to compare P33 (Polish Pekin), P8 (Danish Pekin), and P9 ducks (French Pekin) for body weight, dressing percentage, carcass composition, and selected meat quality traits. A total of 180 ducks, 30 males and 30 females of each strain, were kept indoors on deep litter and fed complete commercial diets ad libitum. At the end of 8 wk, the ducks were weighed and 7 males and 7 females of each strain (42 birds in total) were slaughtered and dissected. Read More

Osteoporos Int 2019 Feb 22. Epub 2019 Feb 22.

Post-Graduate Program in Epidemiology, Federal University of Pelotas, Pelotas, Brazil.

The association between moderate and vigorous physical activity throughout adolescence and areal bone density (aBMD) at 18 years of age was evaluated. Vigorous-intensity physical activity at 11, 15, and 18 years was associated with aBMD in early adulthood, especially in boys. Cross-sectional analyses showed a positive association between moderate physical activity and aBMD. Read More

JAMA Otolaryngol Head Neck Surg 2019 Feb 21. Epub 2019 Feb 21.

Department of Otolaryngology-Head and Neck Surgery, Saint Louis University, St Louis, Missouri.

Importance: Head and neck cancer (HNC) is more common among socioeconomically disenfranchised individuals, making financial burden particularly relevant.

Objective: To assess the financial burdens of HNC compared with other cancers.

Design, Setting, And Participants: In this retrospective review of nationally representative, publicly available survey, data from the Medical Expenditure Panel Survey were extracted from January 1, 1998, to December 31, 2015. Read More

ACS Appl Mater Interfaces 2019 Mar 1;11(10):10226-10236. Epub 2019 Mar 1.

Department of Chemical and Biomolecular Engineering , National University of Singapore (NUS) , 117585 , Singapore.

Stretchable skin-like pressure sensing with minimized and distinguishable strain-induced interference is essential for the development of collision-aware surgical robotics to improve the safety and efficiency of minimally invasive surgery in a confined space. Inspired by the multidimensional wrinkles of Shar-Pei dog's skin for tactile sensing, we developed a stretchable pressure sensor consisting of reduced graphene oxide (rGO) electrodes with biomimetic topographies to improve the robot-tissue collision detections. A facile fabrication route for stretchable rGO electrodes was first demonstrated by harnessing the surface instability during the sequential deformation processes. Read More

Psychooncology 2019 Apr 7;28(4):863-871. Epub 2019 Mar 7.

Institute of Health & Society, Newcastle University, Newcastle upon Tyne.

Objective: Cancer survivors are susceptible to financial hardship. In head and neck cancer (HNC) survivors, we investigated (a) predictors for cancer-related financial hardship and (b) associations between financial hardship and health-related quality of life (HRQoL).

Methods: We conducted a cross-sectional study in HNC survivors identified from the National Cancer Registry Ireland. Read More

Rev Med Inst Mex Seguro Soc 2019 Jan 28;56(5):456-461. Epub 2019 Jan 28.

Secretaría de Salud, Hospital General de México “Dr. Eduardo Liceaga”, Unidad de Neumología y Cirugía de Tórax. Ciudad de México, México

Background: Tuberculosis is a global public health problem, especially in emerging countries. Mycobacterium tuberculosis is the main cause of cervical lymphadenopathy; nontuberculous mycobacteria are relatively common in children and rare in adults.

Objective: To identify and establish the frequency of infectious etiology by nontuberculous mycobacteria in Mexican adult patients with cervical lymphadenopathy. Read More

J Ultrason 2018 ;18(75):284-289

Department of Radiology, Ankara University, Faculty of Medicine , Ankara , Turkey.

The aim of the study was to evaluate the performance of real-time strain sonoelastography for comparison of perithyroidal lymph nodes of Hashimoto thyroiditis patients, jugular lymph nodes of healthy individuals and parathyroid lesions. Fifty parathyroid lesions (Group 1), 52 lymph nodes in Hashimoto thyroiditis patients (Group 2) and 51 reactive jugular lymph nodes (Group 3) were examined by ultrasound, and elastography was performed for a total of 95 patients. Real-time strain sonoelastography using elasticity score (E-index) was performed. Read More

Int Forum Allergy Rhinol 2019 Feb 12. Epub 2019 Feb 12.

Department of Otolaryngology-Head and Neck Surgery, Basil Hetzel Institute for Translational Health Research, The Queen Elizabeth Hospital, University of Adelaide, Woodville South, SA, Australia.

Background: Topical budesonide (Pulmicort; AstraZeneca AB, Sodertalje, Sweden) is commonly used in the management of chronic rhinosinusitis (CRS). Although its use is due to its perceived anti-inflammatory effect, studies have suggested that it may also have antibacterial properties. To make the hydrophobic steroid molecule suitable for topical administration, pharmaceutical excipients are used in commercial steroid formulations. Read More

Disabil Rehabil Assist Technol 2019 Feb 7:1-6. Epub 2019 Feb 7.

a Department of Community Health Science, Graduate School of Health Science , Kobe University , Kobe , Japan.

Purpose: Children with cerebral palsy may face difficulties using handheld pointing devices, due to involuntary muscle movements. This study aimed at describing the idea of the new wearable sensor switch and assessing its feasibility as an access solution in a case of mixed-type cerebral palsy.

Methods: The study participant was a 17-year-old male with mixed-type cerebral palsy characterized by chorea-athetotic movements and bilateral spasticity with gross motor function classification system level V. Read More

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Nov;32(22):1714-1718

Department of Gastroenterology, Guangdong General Hospital，Guangdong Academy of Medical Sciences.

Patients with laryngopharyngeal reflux frequently experience voice-related symptoms. This was a prospective study that designed to investigate the effectiveness of combined voice and medical therapy in comparison with medical therapy alone in the improvement of voice-related symptoms and parameters in patients with laryngopharyngeal reflux. In this prospective study, total of 71 patients diagnosed with laryngopharyngeal reflux with voice symptoms were randomly divided into 2 groups (A and B). Read More

Comput Methods Biomech Biomed Engin 2019 Feb 4:1-12. Epub 2019 Feb 4.

b Institut de Mécanique et d'Ingénierie , Université de Bordeaux , Talence , France.

The number of hip resurfacing arthroplasty procedures has declined dramatically in recent years, for reasons related to the survival rate. Some studies suggest that metal particles are the main critical problem, but do not specify the effect of femoral position on the failure rate. The present study aims to analyze whether the positioning of the resurfacing head implant is important in the distribution of bone strains and in the risk of fracture of the femur. Read More

Molecules 2019 Jan 31;24(3). Epub 2019 Jan 31.

Chair of Medical and Molecular Genetics Research, Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, King Saud University, P.O. Box 10219, Riyadh 11433, Saudi Arabia.

Currently, global efforts are being intensified towards the discovery of local (Bt) isolates with unique anticancer properties. Parasporins (PS) are a group of Bt non-insecticidal crystal proteins with potential and specific in vitro anticancer activity. However, despite the significant therapeutic potential of PS-producing Bt strains, our current knowledge on the effects of these proteins is limited. Read More

Med Clin North Am 2019 Mar;103(2):357-370

Department of Neurology, Massachusetts General Hospital, 55 Fruit Street, WACC 739B, Boston, MA 02114, USA. Electronic address:

Upper extremity entrapment neuropathies are common and can cause pain, sensory loss, and muscle weakness that lead to functional disability. In this article, the authors review common entrapment neuropathies of the upper extremities, including median neuropathy at the wrist (carpal tunnel syndrome), ulnar neuropathy at the elbow, and radial neuropathy. The authors discuss the pathophysiology of nerve compression and typical etiologies, as well as strategies for differentiating between common mimics such as cervical radiculopathy and for selecting between various treatment modalities. Read More

J Orthop Sports Phys Ther 2019 Feb;49(2):113

A 46-year-old male soldier reported to an emergency department with severe acute neck pain immediately following a hyperflexion injury during recreational skydiving. He was evaluated in the emergency department, including radiographs, and released with a diagnosis of "acute neck strain." After presenting with continued neck pain, he was sent for consultation with a physical therapist. Read More

J Insect Sci 2019 Jan 1;19(1). Epub 2019 Jan 1.

Silk Biotechnology Laboratory, School of Biology and Basic Medical Sciences, Soochow University; National Engineering Laboratory for Modern Silk, Soochow University, Suzhou, PR China.

The silk sericin hydrolysate (SSH) from the waste of silk processing as a substitute of fetal bovine serum (FBS) was used for the culture of Chinese hamster ovary (CHO) cells and Henrietta Lacks (Hela) strain of human cervical cancer cells. The survival ratio of these cells cultured in SSH media were similar to or higher than those in FBS media. Especially after the serum was replaced by low concentration of SSH at 15. Read More

PLoS One 2019 24;14(1):e0210429. Epub 2019 Jan 24.

Department of Sports Medicine and Sports Nutrition, Ruhr-University Bochum, Bochum, Germany.

Background: The prevalence of back pain in athletes has been investigated in several studies, but there are still under- or uninvestigated sports discipline like sports exposed to repetitive overhead activity. Elite athletes spend much time in training and competition and, because of the nature of their disciplines, subject their bodies to a great deal of mechanical strain, which puts a high level of stress on their musculoskeletal systems. From this it is hypothesized that elite athletes who engage in repetitive overhead motions experience a higher strain on their spine and thus possibly a higher prevalence of back pain compared with an active control group. Read More

Ann Biomed Eng 2019 Apr 23;47(4):980-989. Epub 2019 Jan 23.

Orthopaedics Biomechanics Laboratory, Sunnybrook Research Institute, Toronto, ON, Canada.

Metastasis of cancer to the spine impacts bone quality. This study aims to characterize vertebral microdamage secondary to metastatic disease considering the pattern of damage and its relationship to stress and strain under load. Osteolytic and mixed osteolytic/osteoblastic vertebral metastases were produced in athymic rats via HeLa cervical or canine Ace-1 prostate cancer cell inoculation, respectively. Read More

Complement Ther Med 2019 Feb 26;42:125-131. Epub 2018 Sep 26.

Centers for Behavioral and Preventive Medicine, The Miriam Hospital, 164 Summit Avenue, Providence, RI, 02906, United States.

Objectives: This study:Healthy Active and in Control (HA1C), examined the feasibility and acceptability of yoga as a complementary therapy for adults with Type-2 Diabetes (T2DM).

Design: A 2-arm randomized clinical trial comparing Iyengar yoga with a supervised walking program.

Setting: Hospital based gym-type facility and conference rooms. Read More

Int Urogynecol J 2019 Jan 17. Epub 2019 Jan 17.

Department of Gynaecology, University Medical Center Utrecht, Utrecht, The Netherlands.

Objective: Pelvic organ prolapse (POP) is clinically diagnosed in the supine position, where the effect of gravity is simulated by having the patients put strain on their pelvic floor. The objective of this study was to determine the degree of POP underestimation in the supine position based on magnetic resonance imaging (MRI) findings.

Methods: This prospective study was conducted with symptomatic POP grade ≥ 2 patients. Read More

Bone 2019 Apr 8;121:107-115. Epub 2019 Jan 8.

Department of Physical Therapy, School of Health and Human Sciences, Indiana University, Indianapolis, IN, United States of America.

The proximal humerus is a common, yet understudied site for osteoporotic fracture. The current study explored the impact of prolonged physical activity on proximal humerus bone health by comparing bone properties between the throwing and nonthrowing arms within professional baseball players. The proximal humerus in throwing arms had 28. Read More

Laryngoscope 2019 Jan 10. Epub 2019 Jan 10.

Department of Otolaryngology-Head and Neck Surgery, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, U.S.A.

Objective: Clinical outcomes for type I Gore-Tex thyroplasty (GMT) for nonparalytic glottic incompetence (GI) have been reported in the literature. Given differences in male and female laryngeal anatomy, sex-based outcomes should also be evaluated. We endeavored to evaluate sex-specific post-GMT voice outcomes. Read More

Vet Med Int 2018 9;2018:9296520. Epub 2018 Dec 9.

Institute of Bioscience, Universiti Putra Malaysia, 43400 UPM Serdang, Selangor, Malaysia.

Newcastle disease virus strains are velogenic, mesogenic, and lentogenic. This study aims to design a scoring system for lesions induced by different strains of Newcastle disease virus in chicken. Three experiments were conducted. Read More

Laryngoscope 2019 Jan 9. Epub 2019 Jan 9.

Department of Surgery, Division of Otolaryngology-Head and Neck Surgery, School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, U.S.A.

Objectives/hypothesis: Vocal fold collagen composition is an important determinant of material properties and mucosal wave propagation. Collagen alignment and straightness are quantitatively characterized by second harmonic generation (SHG) imaging. We examined leporine, canined and porcine vocal folds showing collagen composition variation that is species, location, and strain specific. Read More

Am J Ophthalmol Case Rep 2019 Mar 21;13:122-126. Epub 2018 Dec 21.

Massachusetts Eye Research and Surgery Institution (MERSI), 1440 Main Street, Suite 201, Waltham, MA, 02451, USA.

Aim: To report a case of bilateral papillitis as the initial ophthalmologic presentation in a patient with complex medical history and multisystemic symptoms, eventually revealing a diagnosis of sarcoidosis.

Methods: Retrospective interventional case report.

Report: A 54-year-old Caucasian woman presented with bilateral decreased vision, photophobia and eye pain for a month. Read More