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IEEE J Biomed Health Inform 2021 Jun 14;PP. Epub 2021 Jun 14.

Cervical spondylosis has gradually become a high-incidence disease in today's society. The cervical range of motion (CROM) is widely used as the evaluation criterion of cervical status, whereas the existing methods of CROM measuring are not humanized enough. Consequently, the purpose of this study was to develop a novel photogrammetric method to assess three-dimensional CROM. Read More

Spine J 2021 Jun 9. Epub 2021 Jun 9.

Department of Neurosurgery, Ansan Hospital, Korea University College of Medicine, Ansan, Republic of Korea. Electronic address:

Background Context: Laminoplasty of the cervical spine is widely used as an effective surgical method to treat compressive myelopathy of the cervical spine; however, there is an adverse effect of kyphosis after surgery. The risk factors or predictors of kyphosis have not been sufficiently evaluated.

Purpose: To assess the risk factors for kyphosis following laminoplasty. Read More

Oper Neurosurg (Hagerstown) 2021 Jun 7. Epub 2021 Jun 7.

Department of Orthopaedic Surgery, College of Medicine, Seoul National University, Seoul, Republic of Korea.

Background: Various surgical techniques have been attempted to treat patients with failed anterior subcutaneous transposition performed for cubital tunnel syndrome.

Objective: To analyze intraoperative findings of failed anterior subcutaneous transposition and to report the outcome of in Situ neurolysis of ulnar nerve.

Methods: Patients who, under diagnosis of failed anterior subcutaneous transposition of ulnar nerve, underwent in Situ neurolysis between 2001 and 2018 were included in this study. Read More

Medicine (Baltimore) 2021 Jun;100(22):e26191

Laboratory of Statistics, Graduate School of Medicine, Osaka City University, Osaka, Japan.

Abstract: Case-control studies by examining the lumbar spine computed tomography (CT) findings focusing on the spinous processes."Passing spine" was defined as a lumbar degenerative change observed on CT images. In contrast, kissing spine, which is also an image finding, has been acknowledged as an established clinical condition. Read More

Medicine (Baltimore) 2021 Jun;100(22):e26151

Departments of First Clinical Medical, Shandong University of Traditional Chinese Medicine, Jinan, China.

Rationale: Cervical spondylotic radiculopathy (CSR) is a common sensory, motor, and reflex disorder. Numbness, a common subjective symptom of CSR, lacks objective quantitative indicators and recognized effective treatments, but is also difficult to recover from. We present a case report describing a traditional acupuncture treatment for CSR, utilizing a special acupuncture method and point, namely the Yunmen point. Read More

Cureus 2021 Apr 24;13(4):e14670. Epub 2021 Apr 24.

Neurology, Icahn School of Medicine at Mount Sinai, New York, USA.

Introduction Approximately 5-10% of strokes occur in adults of less than 45 years of age. The rising prevalence of stroke risk factors may increase stroke rates in young adults (YA). We aimed to compare risk factors and outcomes of acute ischemic stroke (AIS) among YA. Read More

Neurosurg Clin N Am 2021 Jul 7;32(3):353-363. Epub 2021 May 7.

Department of Neurosurgery, University of Arizona, Banner University Medical Center, PO Box 245070, 1501 North Campbell Avenue, Room 4303, Tucson, AZ 85724-5070, USA. Electronic address:

This article reviews the historical origins of central cord syndrome (CCS), the mechanism of injury, pathophysiology, and clinical implications. CCS is the most common form of incomplete spinal cord injury. CCS involves a spectrum of neurologic deficits preferentially affecting the hands and arms. Read More

Cureus 2021 May 22;13(5):e15169. Epub 2021 May 22.

Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, USA.

This systematic review determines the efficacy and safety of duloxetine for chronic low back pain (CLBP). We queried the PubMed, SCOPUS, and Ovid MEDLINE databases. All level I and II randomized controlled studies published in the English language investigating the efficacy of duloxetine for chronic low back pain were included. Read More

Medicine (Baltimore) 2021 May;100(21):e26150

Department of Spine Surgery, Fuzhou Second Hospital Affiliated to Xiamen University, Fuzhou, China.

Rationale: The thoracic spine is stabilized in the anteroposterior direction by the rib cage and the facet joints, thus thoracic degenerative spondylolisthesis is very uncommon. Here, we report a rare case of thoracic degenerative spondylolisthesis in which the lower thoracic region was the only region involved.

Patient Concerns: We present the case of a 56-year-old Chinese female who suffered from thoracic degenerative spondylolisthesis. Read More

Acta Ortop Mex 2020 Nov-Dec;34(6):433-440

División de Cirugía de Columna. Instituto Nacional de Rehabilitación «Dr. Luis Guillermo Ibarra Ibarra». Av. México-Xochimilco 289, C.P. 14389. Ciudad de México. México.

There are various approaches and surgical techniques with the objective of nerve root decompression, restrict mobility, and fusion of the listhesis. Among the techniques, posterior interbody fusion combines direct and indirect root decompression with the fusion between vertebral bodies, placing an autologous bone graft between transverse apophysis and vertebral bodies. Transforaminal lumbar and posterior interbody fusion, on the same way, look to decompress and fuse but with a different approach to the spine. Read More

Acta Ortop Mex 2020 Nov-Dec;34(6):412-416

Clínica de Columna de la Secretaría de Salud de la Ciudad de México. Hospital General «La Villa». México.

Traumatic spondyloptosis is a serious injury usually caused by high-energy trauma; It consists of the anterior or posterior dislocation of 100% or more of the underlying vertebral body, which can become a total injury of the spinal cord, producing a neurological deficit; this type of injury represents stage 4 and 5 of Allen-Ferguson. A 50-year-old man who suffers a car accident, he receive frontal impact when he was a driver, colliding with the retaining wall, referred from another hospital to emergency room, managed with C7 hemicorpectomy, c7-t1 discectomy, spondylodesis with anterior plate (C6-T1), and posterior approach + Fascetectomies of C7-T1, facet joint screws C6 and transpedicular fixation of T1. Subaxial cervical spondyloptosis is relatively rare clinical entity, a complete clinical examination is important in diagnosis, taking in considerations the injury mechanism. Read More

JMIR Med Inform 2021 May 21;9(5):e14755. Epub 2021 May 21.

Xi'an Key Laboratory of Cardiovascular and Cerebrovascular Diseases, The Affiliated Hospital of Northwest University Xi'an Number 3 Hospital, Xi'an, China.

Background: Disk herniation and disk bulge are two common disorders of lumbar intervertebral disks (IVDs) that often result in numbness, pain in the lower limbs, and lower back pain. Magnetic resonance (MR) imaging is one of the most efficient techniques for detecting lumbar diseases and is widely used for making clinical diagnoses at hospitals. However, there is a lack of efficient tools for effectively interpreting massive amounts of MR images to meet the requirements of many radiologists. Read More

Am J Transl Res 2021 15;13(4):2804-2812. Epub 2021 Apr 15.

Department of Tuina and Rehabilitation Medicine, Hubei Provincial Hospital of Traditional Chinese Medicine, Hubei Province Academy of Traditional Chinese Medicine, Hubei University of Chinese Medicine Wuhan 430061, Hubei Province, China.

Objective: This study was designed to study the effects of massage and acupuncture on patients with frozen shoulder complicated with cervical spondylosis through range of motion (ROM) and daily living ability.

Methods: A total of 164 patients with frozen shoulder treated in our hospital from June 2016 to April 2019 were recruited and divided into a control group and an observation group. There were 100 cases in the observation group, all of whom were treated with massage combined with acupuncture. Read More

J Int Med Res 2021 May;49(5):3000605211015559

Department of Orthopaedic Surgery, 183174Fukushima Medical University School of Medicine, Fukushima City, Fukushima, Japan.

The incidence of lumbar spondylolysis is affected by sex, race, and congenital abnormalities. These differences suggest a genetic component to the etiology of spondylolysis. However, no definitive evidence has been presented regarding the inheritance of lumbar spondylolysis. Read More

Aten Primaria 2021 May 14;53(8):102023. Epub 2021 May 14.

Unitat de Suport a la Recerca Metropolitana Sud, Institut Universitari d'Investigació en Atenció Primària Jordi Gol (IDIAP Jordi Gol), Spain.

Patients who experience both vertigo and nystagmus in the Dix-Hallpike test (DHT) are diagnosed with objective benign paroxysmal positional vertigo (BPPV). This test provokes only vertigo in between 11% and 48% of patients, who are diagnosed with subjective BPPV. Detection of nystagmus has important diagnostic and prognostic implications. Read More

World Neurosurg 2021 May 12. Epub 2021 May 12.

Department of Pain Management, Xuanwu Hospital, Capital Medical University, Beijing, China. Electronic address:

Objective: Cervical chest pain (CCP), as 1 atypical symptom associated with cervical spondylosis, often overlaps with other chest-related diseases. CCP obviously relieved after ultrasound-guided cervical nerve root block near a herniated disc should be considered as a potential pathologic source. The purpose of this study is to investigate whether coblation discoplasty can alleviate CCP after positive ultrasound-guided nerve root block. Read More

AJNR Am J Neuroradiol 2021 May 13. Epub 2021 May 13.

Center for Magnetic Resonance in Biology and Medicine (G.B., H.R., L.P., S.L., V.C.), Assistance Publique-Hôpitaux de Marseille, Hôpital Universitaire Timone, Marseille, France

Background And Purpose: Although current radiologic evaluation of degenerative cervical myelopathy by conventional MR imaging accurately demonstrates spondylosis or degenerative disc disease causing spinal cord dysfunction, conventional MR imaging still fails to provide satisfactory anatomic and clinical correlations. In this context, we assessed the potential value of quantitative cervical spinal cord T1 mapping regarding the evaluation of patients with degenerative cervical myelopathy.

Materials And Methods: Twenty patients diagnosed with mild and moderate-to-severe degenerative cervical myelopathy and 10 healthy subjects were enrolled in a multiparametric MR imaging protocol. Read More

ACS Appl Mater Interfaces 2021 May 13;13(20):23905-23914. Epub 2021 May 13.

Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), 30 South Puzhu Road, Nanjing 211816, China.

The growing applications of wearable electronics, electronic textiles, and biomedical devices have sparked explosive demand for high-performance flexible sensors. Herein, we report a facile approach for fabricating a highly sensitive carbon hybrid fiber, which is composed of a graphene fiber skeleton and carbon nanotube (CNT) branches. In this hierarchical fiber, in situ grown CNTs prohibit the stacking of graphene sheets and bridge graphene layers simultaneously, making the hybrid fiber fluffy and conductive. Read More

Cureus 2021 Apr 1;13(4):e14238. Epub 2021 Apr 1.

Neurosurgery, Nara Medical University, Kashihara, JPN.

Cervical spondylotic myelopathy (CSM) is a common age-related disease, but little is known concerning the impact of cervical facet degeneration in patients suffering from CSM without degenerative cervical spondylolisthesis or cervical instability. We report an instructive case of CSM with rapid neurological deterioration in which unilateral degenerative facet joint pathology at the affected spinal level and impressive radiological findings were observed. A 70-year-old female progressively developed C5 segmental myelopathy without any trauma within a two-week period. Read More

J Orthop Surg Res 2021 May 5;16(1):298. Epub 2021 May 5.

Department of Neurosurgery, Dokuz Eylul University Medical Faculty, Izmir, Turkey.

Objective: We aimed to evaluate reliability, radiological outcomes, and the impacts of anterior cervical hybrid construction on the adjacent segments for the multilevel cervical degenerative disc disease (mCDDD) and spondylotic spinal stenosis (SSS).

Methods: A retrospective analysis was performed using data extracted from the medical files of 195 patients (105 males, 90 females; mean age: 47.7 years). Read More

Medicine (Baltimore) 2021 May;100(18):e25824

Department of Spinal Surgery, Peking University People's Hospital, Peking University, Beijing, P.R. China.

Abstract: As the technology of combining with fusion and nonfusion procedure, cervical hybrid surgery (HS) is an efficacious alternative for treatment with cervical spondylotic myelopathy. While studies on cervical alignment between 3-level HS and anterior cervical discectomy and fusion (ACDF) were seldom reported. The effects of cervical imbalance on its related clinical outcomes are yet undetermined as well. Read More

Medicine (Baltimore) 2021 May;100(18):e25570

Henan Medical College, Zhengzhou.

Background: Cervical Spondylotic radiculopathy (CSR) is the most common spinal degenerative disease. Its clinical manifestations are pain and numbness in the neck and arm and limitation of neck movement, which greatly affects the life and work of patients. Acupuncture and electroacupuncture are commonly used in China, the efficacy of acupuncture has been confirmed. Read More

Healthcare (Basel) 2021 Apr 29;9(5). Epub 2021 Apr 29.

School of Health Sciences, Faculty of Clinical Engineering, Fujita Health University, Toyoake 470-1192, Japan.

Various factors significantly affect the risk of falls among older adults with lumbar spondylosis. However, the relationship between falls and trunk muscle strength in older men is poorly explored. Thus, we aimed to investigate the relationship between back muscle strength and fall risk in older men and women with lumbar spondylosis. Read More

Int J Environ Res Public Health 2021 04 12;18(8). Epub 2021 Apr 12.

Department of Physical Medicine & Rehabilitation, College of Medicine, Kyung Hee University, Seoul 02447, Korea.

The objective of this study was to assess the cross-sectional areas (CSA) of lumbar paraspinal muscles and their fatty degeneration in adults with degenerative lumbar spondylolisthesis (DLS) diagnosed with chronic radiculopathy, compare them with those of the same age- and sex-related groups with radiculopathy, and evaluate their correlations and the changes observed on magnetic resonance imaging (MRI). This retrospective study included 62 female patients aged 65-85 years, who were diagnosed with lumbar polyradiculopathy. The patients were divided into two groups: 30 patients with spondylolisthesis and 32 patients without spondylolisthesis. Read More

Br J Neurosurg 2021 Apr 29:1-4. Epub 2021 Apr 29.

Department of Spine surgery, Changzheng Hospital, Naval Medical University, Shanghai, China.

A 60-year-old male patient complained of weakness of both legs for one year, intermittent fever for two months, up to 38.0 °C. Physical examination showed bilateral hyperreflexia of knee tendon and positive Hoffman sign on the right side. Read More

Spine (Phila Pa 1976) 2021 Apr 23. Epub 2021 Apr 23.

Department of Orthopaedic Surgery, University of Pittsburgh Medical Center Department of Neurosurgery, University of Pittsburgh Medical Center.

Study Design: Prospective cohort study.

Objective: To identify surgical factors that affect adjacent segment kinematics after anterior cervical discectomy and fusion (ACDF) as measured by biplane radiography.

Summary Of Background Data: Previous studies investigated the effect of surgical factors on spine kinematics as a potential etiology for adjacent segment disease (ASD). Read More

Praxis (Bern 1994) 2021 Apr;110(6):324-335

Klinik für Neurochirurgie, Kantonsspital St. Gallen, St. Gallen.

Acute Traumatic Central Cord Syndrome: Etiology, Pathophysiology, Clinical Manifestation, and Treatment The acute traumatic central cord syndrome (ATCCS) represents an injury to the spinal cord with disproportionately greater motor impairment of the upper than the lower extremities, with bladder dysfunction and with varying degrees of sensory loss below the level of the respective lesion. The mechanism of ATCCS is most commonly a traumatic hyperextension injury of the cervical spine at the base of an underlying spondylosis and spinal stenosis. The mean age is 53 years, and segments C4 to Th1 are most frequently affected. Read More

Cureus 2021 Mar 23;13(3):e14062. Epub 2021 Mar 23.

Orthopedics and Sports Medicine, Houston Methodist Hospital, Houston, USA.

This systematic review compares clinical outcomes between platelet-rich plasma (PRP) and corticosteroid injections for the treatment of lumbar spondylosis and sacroiliac arthropathy. A systematic review was registered with the International Prospective Register of Systematic Reviews (PROSPERO) and performed according to Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines using the Pubmed, SCOPUS, and Ovid MEDLINE databases. All level I-III evidence comparative studies published in the English language investigating the clinical outcomes between PRP and corticosteroid injections for the treatment of lumbar spondylosis and sacroiliac arthropathy were included. Read More

Zhongguo Gu Shang 2021 Apr;34(4):333-6

Department of Radiology, the First People's Hospital of Xiaoshan, Hangzhou 311200, Zhejiang, China.

Objective: To explore the relationship between lumbar degenerative spondylolisthesis and T2WI high signal in the interspinous ligament in MRI in order to improve the understanding of the signal changes of the interspinous ligament.

Methods: The clinical data of 43 patients with clinically diagnosed lumbar degenerative spondylolisthesis were collected from March 2018 to March 2020, there were 19 males and 24 females, aged 50 to 92 years with an average of 69 years old. Using picture archiving and communication systems (PACS) to access images and record the distribution and incidence of T2WI high signal in the interspinous ligament between the slipped and non-slipped segments. Read More