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Medicine (Baltimore) 2021 Jun;100(25):e26385

Inanami Spine and Joint Hospital, Higashishinagawa, Shinagawa-ku, Tokyo, Japan.

Rationale: For isthmic lumbar spondylolisthesis (ILS) associated with the removal of herniation, it remains challenging to perform less invasive and minimally disruptive procedures. Good results could potentially be obtained by further preserving the posterior elements in full-endoscopic lumbar discectomy (FESS), which is less invasive than microenscopic surgery (MES).

Patient Concerns: One patient complained of left leg pain, and another patient complained of right leg pain and low back pain. Read More

Pain Res Manag 2021 1;2021:8850281. Epub 2021 Jun 1.

Department of Physical Medicine & Rehabilitation, Jeonbuk National University Medical School, Jeonju 54907, Republic of Korea.

Objective: Dermatomal somatosensory evoked potentials (DSEPs) are used to evaluate abnormalities of the somatosensory tract. There have been some studies on the diagnostic value of DSEP in radiculopathy, but it is still controversial. The purpose of our study is to evaluate the diagnostic implication and clinical relevance of DSEPs in patients with radiculopathy by comparing DSEP findings to radiculopathy symptoms and intervertebral foramen (IVF) or spinal canal stenosis in lumbar magnetic resonance imaging (MRI). Read More

Zh Vopr Neirokhir Im N N Burdenko 2021 ;85(3):29-43

Treatment and Rehabilitation Center, Moscow, Russia.

Objective: To evaluate the correlation of trigeminal radiculopathy with anatomical relationships of trigeminal nerve root, brainstem, tumors and vessels in patients with vestibular schwannomas.

Material And Methods: A retrospective analysis included 153 patients (106 females and 47 males aged 22-82 years) with vestibular schwannomas who underwent surgery via retromastoid approach. Preoperative trigeminal radiculopathy (facial pain and sensory disturbances) was examined after microsurgical resection. Read More

Eur J Pain 2021 Jun 22. Epub 2021 Jun 22.

Division of Neurological Pain Research and Therapy, Department of Neurology, University Clinic Schleswig-Holstein, Campus Kiel, Arnold-Heller-Straße 3, 24105, Kiel, Germany.

Background And Objectives: Reduced laser evoked potential (LEP) habituation indicates abnormal central pain processing. But the paradigm (4 stimulation blocks a 25 stimuli) is time-consuming and potentially omits important information on the exact habituation time course. This study examined whether a high temporal resolution (HTR) analysis (dividing the 4 stimulation blocks into 12 analysis blocks) can answer the following questions: 1)After how many stimuli does LEP-habituation occur? 2)Is there a difference in LEP-habituation in younger versus older subjects? 3)Is HTR applicable on radiculopathy patients?

Methods: EEG data of 129 subjects were included. Read More

BMJ Case Rep 2021 Jun 21;14(6). Epub 2021 Jun 21.

National Neuroscience Institute - Singapore General Hospital Campus, Singapore.

In this report, we describe a patient who developed an acute trigeminal neuritis and cervical radiculitis after receiving a Pfizer-BioNtech vaccination (tozinameran) against SARS-CoV-2. Read More

Br J Neurosurg 2021 Jun 21:1-3. Epub 2021 Jun 21.

Neurosurgery Department, Hospital Universitari De Girona Dr. Josep Trueta, Girona, Spain.

The aim of this study was to describe a very rare presentation of ependymoma that can derive from intraoperative complications for surgeons and increased morbidity for the patients. Multiple cases of mobile cauda equina tumors leading to inadequate approach have been reported in the literature, however, the reports of ependymoma histology are very rare. This report describes the third adult case in recent years and a retrospective review of cases reported in the literature until today. Read More

World J Clin Cases 2021 Jun;9(17):4433-4440

Department of Physical Medicine and Rehabilitation, College of Medicine, Chung-Ang University, Seoul 06973, South Korea.

Background: Intraneural ganglion cysts are benign gelatinous masses that form within the epineurium of a peripheral nerve. Only few cases of intraneural ganglion cyst arising from the hip joint have been reported.

Case Summary: A previously healthy 65-year-old woman who had been experiencing left buttock pain radiating to the dorsum of the foot for 2 years visited our clinic. Read More

World J Clin Cases 2021 Jun;9(17):4303-4309

Department of Rehabilitation Medicine, Hanyang University Hospital, Seoul 04763, South Korea.

Background: Herpes zoster is a painful infectious disease caused by the varicella zoster virus. Herpes zoster radiculopathy, which is a type of segmental zoster paresis, can complicate the disease and cause motor weakness. This complication should be considered when a patient with a rash complains of acute-onset motor weakness, and the diagnosis can be verified electrodiagnostic study. Read More

BJR Case Rep 2021 May 24;7(3):20200126. Epub 2021 Feb 24.

Royal Derby Hospital, Derby, UK.

Prolapsed intervertebral discs are commonly associated with back ache and sciatica. Management is often conservative with analgesia and physiotherapy. Nerve root injections and discectomy procedures are used where conservative measures fail. Read More

Brain Nerve 2021 Jun;73(6):659-670

Department of Neurology, Chubu Rosai Hospital.

The most caudal part of the spinal cord shows special anatomical characteristics and it contains epiconus (L4-S2 segments), the conus medullaris (S3-S5 segments), and surrounding nerve roots. Lesions of the thoracolumbar junction cause epiconus or conus syndrome. Epiconus syndrome is characterized by segmental muscular weakness and atrophy of one or both lower extremities, often accompanied by foot drop. Read More

J Orthop Surg Res 2021 Jun 14;16(1):380. Epub 2021 Jun 14.

Department of Orthopedic Surgery, Spine Center, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, 1, Singil-ro, Yeongdeungpo-gu, Seoul, Republic of Korea, 07441.

Background: Lower lumbar osteoporotic vertebral compression fracture in extremely elderly patients can often lead to lumbosacral radiculopathy (LSR) due to delayed vertebral collapse (DVC). Surgical intervention requires posterior instrumented lumbar fusion as well as vertebral augmentation or anterior column reconstruction depending on the cleft formation and intravertebral instability. However, it is necessary to decide on surgery in consideration of the patient's frail status, surgical invasiveness, and rehabilitation. Read More

Clin Spine Surg 2021 Jul;34(6):206-215

Department of Orthopedic Surgery, Northwestern Memorial Hospital, Chicago, IL.

Patients presenting to an outpatient spine clinic frequently report symptoms of low back pain with associated buttock, groin, and lower extremity pain. While many of these individuals suffer from lumbar spine radiculopathy, a number of different orthopedic pathologies can mimic these symptoms. Management depends substantially on a detailed history and physical examination, in addition to working from a broad list of differential diagnoses when evaluating these patients. Read More

J Clin Neurosci 2021 Jul 5;89:68-70. Epub 2021 May 5.

College of Medicine & Dentistry, James Cook University, 1 James Cook Dr, Townsville, QLD, Australia.

Spinal teratoma with associated neuroendocrine tumour (NET) is a rare entity. To date there have been only three such cases reported in the literature. Information available to clinicians regarding clinical presentation, behaviour of this tumour over time, management options and follow-up, are as a consequence very limited. Read More

Rev Esp Cir Ortop Traumatol 2021 Jul-Aug;65(4):264-271

Servicio de Neurofisiología Clínica, Hospital General Universitari de Castelló, Castelló, Spain.

Objective: To describe iatrogenic lesions of the peripheral nervous system and their relationship with different orthopaedic and traumatological procedures, through their assessment by means of electromyographic study.

Material And Methods: Retrospective descriptive study of the electromyographies performed in the clinical neurophysiology service of the Hospital General Universitari de Castelló between July 2015 and March 2019, recovering those in which the aetiology was diagnosed as iatrogenic in relation to surgical procedures and analysing those that were initiated after orthopaedic and traumatological procedures.

Results: Of the total number of electromyographies reviewed, 1. Read More

Spine (Phila Pa 1976) 2021 Jun 8. Epub 2021 Jun 8.

St. Joseph's University Medical Center, Department of Orthopaedic Surgery, Paterson, NJ.

Study Design: Retrospective Cohort Study.

Objective: To compare MI-PCF and ACDF in the treatment of unilateral cervical radiculopathy.

Summary Of Background Data: Minimally invasive posterior cervical foraminotomy (MI-PCF) has been shown to be equally effective as ACDF in treating cervical radiculopathy due to foraminal stenosis and similar pathologies. Read More

Oper Neurosurg (Hagerstown) 2021 Jun 7. Epub 2021 Jun 7.

Department of Neurological Surgery, Miller School of Medicine, University of Miami, Miami, Florida, USA.

Lumbar radiculopathy often results from direct compression of the exiting nerve roots. This may be caused mainly by spondylotic changes with any contribution from components like a herniated disc, facet overgrowth, and ligamentum flavum hypertrophy, or any combination of them. There are a wide range of surgical treatments directed at decompressing the neural elements. Read More

Radiol Case Rep 2021 Jul 27;16(7):1919-1923. Epub 2021 May 27.

Department of Physical Therapy and Rehabilitation, AZ Delta Hospital, Torhout/Roeselare, Belgium.

Vertebral artery loop formation is a rare cause of cervical radiculopathy. We report a case of a 70-year-old man who was referred because of a chronic cervicobrachialgia. Initial plain cervical x-ray showed widening of the left C3-C4 intervertebral foramen. Read More

Medicine (Baltimore) 2021 Jun;100(22):e26151

Departments of First Clinical Medical, Shandong University of Traditional Chinese Medicine, Jinan, China.

Rationale: Cervical spondylotic radiculopathy (CSR) is a common sensory, motor, and reflex disorder. Numbness, a common subjective symptom of CSR, lacks objective quantitative indicators and recognized effective treatments, but is also difficult to recover from. We present a case report describing a traditional acupuncture treatment for CSR, utilizing a special acupuncture method and point, namely the Yunmen point. Read More

Spine J 2021 Jun 1. Epub 2021 Jun 1.

Lahey Hospital & Medical Center, 41 Mall Road Charles A, Fager Chairman, Department of Neurosurgery, Associate Professor, Tufts University School of Medicine, Burlington, MA 01805-0105.

Background Context: High quality evidence is difficult to generate, leaving substantial knowledge gaps in the treatment of spinal conditions. Appropriate use criteria (AUC) is a means of determining appropriate recommendations when high quality evidence is lacking.

Purpose: Define appropriate use criteria (AUC) of cervical fusion for treatment of degenerative conditions of the cervical spine. Read More

World Neurosurg 2021 Jun 1. Epub 2021 Jun 1.

Department of Neurological Surgery, Loyola University Medical Center, Maywood, IL; Edward Hines Jr V.A. Medical Center, Hines, IL. Electronic address:

Background: Hemangioblastomas are benign vascular neoplasms of the central nervous system that may occur sporadically or in association with Von Hippel Lindau (VHL) disease. A minority of these lesions can occur in the spine, mostly as intramedullary masses. The authors present a rare CASE of primary sporadic spinal hemangioblastoma occurring as an intradural extramedullary (IDEM) lesion. Read More

Surg Neurol Int 2021 10;12:215. Epub 2021 May 10.

Department of Surgery, Aga Khan University Hospital, Karachi, Sindh, Pakistan.

Background: Lower back pain with radiculopathy due to a disc herniation occurs in about 0.01% of pregnant females. Surgical intervention is seldom required unless there is intractable pain, and for a significant neurological deficit. Read More

Surg Neurol Int 2021 3;12:205. Epub 2021 May 3.

Department of Anaesthesiology and Pain Medicine, Inselspital, Bern University Hospital, University of Bern, Freiburgstrassse, Switzerland.

Background: A spinal dural defect caused by needle placement for spinal level localization is an uncommon complication of cerebrospinal fluid leak with the potential for the development of intracranial hypertension.

Case Description: Our 48-year-old patient underwent unilateral fenestration and sequestrectomy for intractable L5 radiculopathy due to disc herniation at the level L4-5 on the right side. The spinal level was identified with fluoroscopy after placement of a 24-gauge Sprotte spinal needle on the right side. Read More

Eur Spine J 2021 Jun 3. Epub 2021 Jun 3.

IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

Background And Purpose: In cases of spine surgical revisions of patients affected by sagittal malalignment, the restoration of the ideal lumbar lordosis (LL) is mandatory. ALIF procedures represent a powerful and effective approach to improve the LL in case of hypolordosis. This study evaluates the feasibility of ALIF to overpower posterior lumbar instrumentation and fusion mass in revision spine surgery and secondarily to estimate complications, clinical and radiological outcomes. Read More

J Int Med Res 2021 Jun;49(6):3000605211019664

Department of Orthopaedics, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China.

Delayed neurological deficits secondary to percutaneous vertebroplasty caused by cement leakage is a rare condition. Although cement extravasation during percutaneous vertebroplasty is not uncommon, most cases are clinically asymptomatic, and symptomatic cement extravasation that requires surgical excision is rarely reported. Herein, a case of L4 radiculopathy secondary to cement leakage is reported that involved the delayed onset of neurological symptoms. Read More

Int J Spine Surg 2021 Jun 1;15(3):458-465. Epub 2021 Apr 1.

Department of Orthopaedic Surgery, Rothman Institute, Thomas Jefferson University, Philadelphia, Pennsylvania.

Background: Currently, no authors of existing studies have attempted to classify the signal characteristics of disc herniation on magnetic resonance imaging (MRI) and their temporal relationship to symptoms of lumbar radiculopathy. The purpose of this study was to determine whether the MRI signal characteristics are predictive of acuity of symptoms in patients with lumbar disc herniation (LDH).

Methods: A retrospective cohort study was conducted on patients treated at an academic center for LDH from 2015 to 2018. Read More

J Clin Med 2021 May 30;10(11). Epub 2021 May 30.

Private Orthopedic Spine Center, 97080 Würzburg, Germany.

(1) Background: Reconditioning of the paraspinal lumbar extensor muscles by isolated lumbar extension resistance exercises (ILEX) has shown good clinical results for patients with chronic unspecific low back pain. However, the clinical value and safety for patients with specific spine pathologies is unclear. In this study, clinical outcome and influencing factors were retrospectively analyzed for patients with lumbar disk herniation (LDH) and radiculopathy. Read More

Neurol Int 2021 May 6;13(2):190-194. Epub 2021 May 6.

Neuroscience Centre, Neurology Department, King Fahad Specialist Hospital-Dammam, Dammam 31444, Saudi Arabia.

Guillain-Barré syndrome (GBS) is an acute, immune-mediated inflammatory peripheral polyneuropathy characterized by ascending paralysis. Most GBS cases follow gastrointestinal or chest infections. Some patients have been reported either following or concomitant with head trauma, neurosurgical procedures, and rarely hemorrhagic stroke. Read More

Neurosurg Focus 2021 Jun;50(6):E7

2Department of Neurological Surgery, University of Washington, Seattle, Washington; and.

Objective: Anterior cervical discectomy and fusion (ACDF) is the most common treatment for degenerative disease of the cervical spine. Given the high rate of pseudarthrosis in multilevel stand-alone ACDF, there is a need to explore the utility of novel grafting materials. In this study, the authors present a single-institution retrospective study of patients with multilevel degenerative spine disease who underwent multilevel stand-alone ACDF surgery with or without cellular allograft supplementation. Read More

BMJ Case Rep 2021 May 31;14(5). Epub 2021 May 31.

Rheumatology Department, James Paget University Hospitals NHS Foundation Trust, Great Yarmouth, UK.

Gout is a common crystal-induced arthropathy affecting mainly the joints of the appendicular skeleton; however, rarely this condition affects the axial skeleton as well. Spinal gout can cause radiculopathy, cord compression, canal stenosis and discitis. We describe a case of a 71-year-old woman where the initial presentation of destructive arthropathy and spinal masses secondary to axial gout was mistaken for a metastatic malignancy. Read More

Vet Anaesth Analg 2021 May 5. Epub 2021 May 5.

Department of Veterinary Clinical Sciences, School of Veterinary Medicine, Louisiana State University, Baton Rouge, LA, USA. Electronic address:

Objectives: To develop an ultrasound-guided cervical perineural injection technique for horses and to evaluate and compare the distribution of contrast agent among perineural, intra-articular and periarticular injections.

Study Design: Prospective, experimental cadaveric study.

Animals: A total of 14 equine cadaveric necks. Read More