2,272 results match your criteria Cervical Disc Disease


Clinical presentation and outcome after anterior cervical discectomy and fusion for degenerative cervical disc disease.

J Craniovertebr Junction Spine 2019 Jan-Mar;10(1):28-32

Department of Neurosurgery, Narayana Medical College Hospital, Nellore, Andhra Pradesh, India.

Background: Anterior cervical discectomy and fusion (ACDF) is a well-described surgical approach for symptomatic degenerative cervical disc disease which does not respond to conservative management. In the present study, we assessed clinical presentation and outcomes of ACDF.

Materials And Methods: The present study was conducted from October 1, 2015, to October 31, 2017, in the Department of Neurosurgery, Narayana Medical College and Hospital, Nellore, Andhra Pradesh, among 100 consecutive adult patients who underwent single- or two-level ACDF for degenerative cervical disc disease. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_87_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6469327PMC

Safety and efficacy of cervical disc arthroplasty in preventing the adjacent segment disease: a meta-analysis of mid- to long-term outcomes in prospective, randomized, controlled multicenter studies.

Ther Clin Risk Manag 2019 28;15:531-539. Epub 2019 Mar 28.

Department of Bioengineering, Institute of Biomedical Engineering, Technical University of Wroclaw, Wroclaw, Poland.

Objectives: Cervical disc arthroplasty (CDA) has become an alternative treatment for cervical radiculopathy and myelopathy. This technique preserves appropriate motion at both the index and adjacent disc levels and consequently may prevent adjacent segment degeneration (ASD). The authors performed a meta-analysis to compare the safety and efficacy of CDA to those of the gold standard, anterior cervical discectomy and fusion (ACDF). Read More

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http://dx.doi.org/10.2147/TCRM.S196349DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6445235PMC
March 2019
2 Reads

[Effectiveness evaluation of Prodisc-C prosthesis for more than 10 years follow-up after total cervical disc replacement].

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2019 Apr;33(4):393-402

Department of Spinal Surgery, Peking University People's Hospital, Beijing, 100044,

Objective: To evaluate long-term radiographic and clinical effectiveness of total cervical disc replacement (TDR) with Prodisc-C prosthesis at a minimum of 10 years follow-up.

Methods: The clinical data of 118 patients with cervical disc degeneration disease (CDDD) treated with TDR by using Prodisc-C prosthesis between December 2005 and April 2008 were retrospectively analyzed. There were 66 males and 52 females, with the age of 25-62 years (mean, 46. Read More

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http://dx.doi.org/10.7507/1002-1892.201810109DOI Listing
April 2019
1 Read

Cervical spondylodiscitis mimicking Pott's disease: a case report.

Eur Rev Med Pharmacol Sci 2019 Apr;23(2 Suppl):1-5

Department of Medical and Surgical Sciences, University Magna Græcia, Catanzaro, Italy.

Introduction: The leading cause of pyogenic vertebral osteomyelitis is Staphylococcus aureus, and its incidence is rising, particularly in the elderly. We report an unusual case of cervical spondylodiscitis and epidural abscess mimicking Pott's disease.

Case Report: A 67-year-old man was admitted to our institution with a 15-day history of neck pain radiating to the head, shoulders and left arm that was associated with weakness and paresthesia. Read More

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http://dx.doi.org/10.26355/eurrev_201904_17467DOI Listing
April 2019
1 Read

Preoperative Chronic Opioid Therapy Negatively Impacts Long Term Outcomes Following Cervical Fusion Surgery.

Spine (Phila Pa 1976) 2019 Apr 5. Epub 2019 Apr 5.

Spine Surgery, Department of Orthopedics and Rehabilitation, University of Iowa Hospitals and Clinics, Iowa City, IA 52242.

MINI: The study investigates the association between preoperative chronic opioid therapy on long-term outcomes (reoperations, ED visits, postoperative opioid use, and adverse events)in patients undergoing primary cervical spine arthrodesis using a commercial claims dataset.

Study Design: Retrospective, observational.

Objective: To define the impact of preoperative chronic opioid therapy (COT) on outcomes following cervical spine fusions. Read More

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http://dx.doi.org/10.1097/BRS.0000000000003064DOI Listing
April 2019
2 Reads

Locking Stand-Alone Cage Constructs for the Treatment of Cervical Spine Degenerative Disease.

Asian Spine J 2019 Apr 10. Epub 2019 Apr 10.

Neurological Center, American British Cowdry Hospital, Mexico City, Mexico.

Study Design: Prospective case series study.

Purpose: Description of the outcome of stand-alone cervical cages for single and multilevel cervical degenerative spine disease.

Overview Of Literature: The aim of anterior cervical discectomy and fusion (ACDF) for cervical spine disease is to improve patient symptoms and spine stability and restore lordosis. Read More

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http://dx.doi.org/10.31616/asj.2018.0234DOI Listing
April 2019
1 Read

The Mobi-C® cervical disc and other devices for two-level disc replacement: overview of its safety and efficacy.

Expert Rev Med Devices 2019 Apr 25;16(4):307-315. Epub 2019 Mar 25.

b Department of Orthopedic Surgery , SUNY Upstate Medical University , Syracuse , NY , USA.

Introduction: Cervical disc arthroplasty (CDA) has become an acceptable alternative for anterior cervical discectomy and fusion (ACDF) for a significant patient population with cervical radiculopathy and/or myelopathy secondary to degenerative changes in the cervical spine. There are sufficient mid- and long-term data supporting performance and safety of one-level CDA. With the success of single-level cervical CDA, considerable interest exists about CDA use for multilevel cervical degenerative disc disease (DDD). Read More

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http://dx.doi.org/10.1080/17434440.2019.1593137DOI Listing
April 2019
2 Reads

How does a novel knitted titanium nucleus prosthesis change the kinematics of a cervical spine segment? A biomechanical cadaveric study.

Clin Biomech (Bristol, Avon) 2019 Mar 5;63:134-139. Epub 2019 Mar 5.

Medical University Innsbruck, Trauma Surgery, Innsbruck, Austria.

Background: Total disc replacement is a possible treatment alternative for patients with degenerative disc disease, especially in the cervical spine. The aim is to restore the physiological flexibility and biomechanical behavior. A new approach based on these requirements is the novel nucleus prosthesis made of knitted titanium wires. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02680033183050
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http://dx.doi.org/10.1016/j.clinbiomech.2019.03.001DOI Listing
March 2019
5 Reads

Cervical hyperaesthesia in dogs: an epidemiological retrospective study of 185 cases.

J Small Anim Pract 2019 Mar 13. Epub 2019 Mar 13.

Dick White Referrals, Six Mile Bottom, Cambridgeshire CB8 0UH, UK.

Objectives: To describe the prevalence, clinical findings and predictors of disease in dogs with cervical hyperaesthesia.

Materials And Methods: Medical records of dogs referred for neurological investigation of cervical hyperaesthesia between 2009 and 2013 were retrospectively reviewed. Dogs were assigned to one of the following groups according to the final diagnosis: Non-Neurologic, Brain, Cervical Spine, Multifocal, and Chiari-like Malformation/Syringomyelia. Read More

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http://dx.doi.org/10.1111/jsap.12987DOI Listing
March 2019
2 Reads

Long-term computed tomography follow-up in great Danes with or without signs of osseous- associated cervical Spondylomyelopathy.

BMC Vet Res 2019 Mar 12;15(1):90. Epub 2019 Mar 12.

College of Veterinary Medicine, The Ohio State University, 601 Vernon L. Tharp St, Columbus, OH, USA.

Background: Osseous- associated cervical spondylomyelopathy (OA-CSM) has a high prevalence in Great Danes. In order to understand the progression of osseous changes, we aimed to perform a long-term computed tomographic (CT) follow-up study of Great Dane dogs with and without OA-CSM. Canine CSM is comparable to a common neurologic disease often diagnosed in older people termed cervical spondylotic myelopathy or degenerative cervical myelopathy, which is progressive in nature. Read More

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http://dx.doi.org/10.1186/s12917-019-1835-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6416867PMC
March 2019
2 Reads

Cervical Artificial Disc Replacement Versus Fusion for Cervical Degenerative Disc Disease: A Health Technology Assessment.

Authors:

Ont Health Technol Assess Ser 2019 19;19(3):1-223. Epub 2019 Feb 19.

Background: Cervical degenerative disc disease is a multifactorial condition that begins with deterioration of the intervertebral disc and results in further degeneration within the spine involving the facet joints and ligaments. This health technology assessment examined the effectiveness, safety, durability, and cost-effectiveness of cervical artificial disc replacement (C-ADR) versus fusion for treating cervical degenerative disc disease.

Methods: We performed a systematic literature search of the clinical evidence comparing C-ADR with fusion. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6394883PMC
April 2019
2 Reads

The use of anterior cervical interbody spacer with integrated fixation screws for management of cervical disc disease.

SICOT J 2019 Jan 8;5. Epub 2019 Feb 8.

Agouza Armed Forces Spine Surgery Center, Farid Shawky Street, Giza, Egypt.

Introduction: Integrated cage and screw designs were introduced for anterior cervical discectomy and fusion (ACDF) and allegedly are superior to anterior plating due to their minimal anterior profile.

Methods: A descriptive study was designed as a prospective case series of 25 patients (30 operated discs) with cervical disc disease treated with a zero-profile cage, and followed up for an average of 16 months (range 12 -18 months). Functional assessment was done with the Neck Disability Index (NDI) and Visual analog scale (VAS) scores for arm and neck pain. Read More

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http://dx.doi.org/10.1051/sicotj/2019002DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405254PMC
January 2019
5 Reads

Biomechanical comparison of percutaneous posterior endoscopic cervical discectomy and anterior cervical decompression and fusion on the treatment of cervical spondylotic radiculopathy.

J Orthop Surg Res 2019 Mar 4;14(1):71. Epub 2019 Mar 4.

Department of Spinal Surgery, Binzhou Medical University Hospital, No. 661 Huanghe 2nd Road, Binzhou, 256603, Shandong, China.

Background: Cervical spondylotic radiculopathy is a common spinal disease. The traditional surgical treatment consists of anterior cervical decompression and fusion (ACDF), but it presents problems such as trauma and fusion complications. Percutaneous posterior endoscopic cervical discectomy (PPECD) is a new minimally invasive technology that has produced good clinical outcome, but further biomechanical comparisons are needed to guide the clinical work. Read More

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http://dx.doi.org/10.1186/s13018-019-1113-1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6399849PMC
March 2019
8 Reads

Cervical Kyphotic Deformity Worsening After Extensor Cervical Muscle Paralysis from Botox Injection: Case Report.

World Neurosurg 2019 Feb 26. Epub 2019 Feb 26.

Department of Neurosurgery, Buffalo, New York USA; Department of Neurosurgery, Buffalo General Medical Center at Kaleida Health, Buffalo, New York USA. Electronic address:

Background: Botulinum toxin (Botox) has long been used therapeutically to treat a variety of diseases, including migraine headaches, cervical spine dystonia, and chronic cervical spine pain, among many others. Although quite useful, Botox has been reported to cause adverse events, some of which may lead to devastating morbidity.

Case Description: We discuss the case of an elderly woman who had severe neck pain after a motor vehicle collision. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.02.057DOI Listing
February 2019
1 Read

Evaluation of Tooth Surface Irradiated With Erbium: Yttrium Aluminum Garnet and Carbon Dioxide Lasers by Atomic Force Microscopy.

J Lasers Med Sci 2018 28;9(3):188-193. Epub 2018 Jul 28.

Laser Research Center of Dentistry, Dentistry Research Institute, Tehran University of Medical Sciences, Tehran, Iran.

Laser irradiation of dentin surface can affect its surface topography and roughness. Atomic force microscopy (AFM) is among the most efficient tools for determination of surface topography of natural biomolecules in nano-scales. Surface roughness affects plaque retention especially in the cervical region. Read More

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http://dx.doi.org/10.15171/jlms.2018.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6378359PMC
July 2018
2 Reads

Preliminary results of anterior cervical arthroplasty by porous alumina ceramic cage for cervical disc herniation surgery.

J Craniovertebr Junction Spine 2018 Oct-Dec;9(4):223-226

Department of Orthopedics, Rottal-Inn-Kliniken GmbH, Eggenfelden, Bayern, Germany.

Objective: Anterior cervical arthroplasty (ACA) is the gold standard surgery in severe or unresponsive cases of cervical disc herniation, uncarthrosis, and foraminal stenosis. The aim of this study is to establish the impact and outcome evaluations of managing the patients operated for cervical arthroplasty by the intersomatic porous alumina ceramic cervical cages (PACC). The authors describe their experience in the area to allow the comparison of effectiveness of ceramic cages versus other interbody fusion cages. Read More

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http://dx.doi.org/10.4103/jcvjs.JCVJS_95_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364365PMC
February 2019
1 Read

Physiotherapy after anterior cervical spine surgery for cervical disc disease: study protocol of a prospective randomised study to compare internet-based neck-specific exercise with prescribed physical activity.

BMJ Open 2019 Feb 19;9(2):e027387. Epub 2019 Feb 19.

Neuro-Orthopedic Center, Ryhov Hospital, Jönköping, Sweden.

Introduction: Patients suffering from remaining disability after anterior cervical decompression and fusion (ACDF) surgery for cervical disc disease may be prescribed physical activity (PPA) or neck-specific exercises (NSEs). Currently, we lack data for the success of either approach. There is also a knowledge gap concerning the use of internet-based care for cervical disc disease. Read More

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http://bmjopen.bmj.com/lookup/doi/10.1136/bmjopen-2018-02738
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http://dx.doi.org/10.1136/bmjopen-2018-027387DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377535PMC
February 2019
9 Reads

Neurological impairment in a patient with concurrent cervical disc herniation and POEMS syndrome.

Eur Spine J 2019 Feb 13. Epub 2019 Feb 13.

Department of Orthopedics, West China Hospital of Sichuan University, Guoxuexiang No. 37, Wuhouqu, Chengdu, 610041, Sichuan, China.

Purpose: POEMS syndrome is a rare clonal plasma cell disease characterized by polyneuropathy, organomegaly, endocrinopathy, M protein, and skin changes. We report a rare case of neurological impairment in patients with concurrent cervical disc herniation and POEMS syndrome.

Methods: A patient presented to a local hospital with C3/4 and C4/5 disc herniation, apparent spinal cord compression concomitant with neurological signs, and concurrent POEMS syndrome. Read More

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http://link.springer.com/10.1007/s00586-019-05914-5
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http://dx.doi.org/10.1007/s00586-019-05914-5DOI Listing
February 2019
2 Reads

Biomechanical effects on the intermediate segment of noncontiguous hybrid surgery with cervical disc arthroplasty and anterior cervical discectomy and fusion: a finite element analysis.

Spine J 2019 Feb 8. Epub 2019 Feb 8.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Rd, Chengdu 610041, China.

Background Context: Surgery for cervical degenerative disc disorder (CDDD) at two noncontiguous segments is infrequent. Few studies have explored the biomechanical effects on the intermediate adjacent segment of anterior cervical discectomy and fusion (ACDF) or cervical disc arthroplasty (CDA) in this situation. No study has examined biomechanical differences between ACDF and hybrid surgery (HS) constructs for noncontiguous CDDD. Read More

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http://dx.doi.org/10.1016/j.spinee.2019.02.004DOI Listing
February 2019
7 Reads

Unusual Case of a Volleyball Athlete Presenting with Posterior Shoulder Pain and Infraspinatus Muscle Wasting.

J Orthop Case Rep 2018 Sep-Oct;8(5):11-14

Department of Orthopaedic Surgery, Singapore General Hospital, Singapore.

Introduction: Entrapment of the suprascapular nerve is an uncommon but important differential in patients who present with posterior shoulder pain. Frequently misdiagnosed as rotator cuff or cervical disc disease, this increasingly recognized entity can result from traction-related or compression-related etiology. Two sites of compression include the suprascapular and spinoglenoid notches with the latter less commonly encountered. Read More

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http://dx.doi.org/10.13107/jocr.2250-0685.1186DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367296PMC
February 2019
1 Read

Autoimmune glial fibrillary acidic protein astrocytopathy.

Curr Opin Neurol 2019 Feb 4. Epub 2019 Feb 4.

Department of Neurology.

Purpose Of Review: To describe a recently characterized autoimmune, inflammatory central nervous system (CNS) disorder known as autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy.

Recent Findings: Affected patients present with symptoms of one or more of meningitis (headache and neck ache), encephalitis (delirium, tremor, seizures, or psychiatric symptoms), and myelitis (sensory symptoms and weakness). Optic disc papillitis (blurred vision) is common. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000676DOI Listing
February 2019
15 Reads

Effect of Social Factors on Surgical Outcomes in Cervical Disc Disease.

Anesth Pain Med 2018 Dec 19;8(6):e84140. Epub 2018 Nov 19.

Department of Neurosurgery, Scanmed St. Raphael Hospital, Cracow, Poland.

Background: Daily clinical practice shows us how diametrically different surgical outcomes can occur in particular groups of patients sharing the same diagnosis and being subjected to the same treatment. Patient-reported outcomes appear to be significantly influenced by social factors and patients' emotional status. Data on such variables were collated and analyzed statistically with the aim of confirming our clinical observations. Read More

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http://anesthpain.com/en/articles/84140.html
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http://dx.doi.org/10.5812/aapm.84140DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347669PMC
December 2018
14 Reads

Biomechanics following skip-level cervical disc arthroplasty versus skip-level cervical discectomy and fusion: a finite element-based study.

BMC Musculoskelet Disord 2019 Jan 31;20(1):49. Epub 2019 Jan 31.

Department of Orthopedic Surgery, West China Hospital, Sichuan University, No. 37 Guo Xue Rd, Chengdu, 610041, Sichuan, China.

Background: Moderately increased motion at the intermediate segment (IS) after skip-level fusion may accelerate disc degeneration. However, limited biomechanical data are available that examine the effects on the IS following cervical disc arthroplasty (CDA). The purpose of this study is to investigate the biomechanical changes in the IS of the cervical spine after skip-level fusion or skip-level arthroplasty. Read More

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http://dx.doi.org/10.1186/s12891-019-2425-3DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6357490PMC
January 2019
2 Reads

Balance problems and dizziness after neck surgery - associations with pain and health-related quality of life.

Physiother Theory Pract 2019 Jan 27:1-8. Epub 2019 Jan 27.

a Department of Medical and Health Sciences, Division of Physiotherapy , Linköping University , Linköping , Sweden.

Introduction: Symptoms of dizziness or imbalance are often present in individuals with a variety of neck-disorders. The aims of this study were to determine the prevalence of patient-reported balance problems and dizziness 10-13 years after surgery for cervical degenerative disc disease; evaluate associations with neck pain and health-related quality of life; and investigate how these individuals described dizziness.

Material And Methods: Sixty-eight individuals, 10 years or more after anterior cervical decompression and fusion surgery, who previously participated in a randomized controlled trial were included. Read More

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http://dx.doi.org/10.1080/09593985.2019.1571137DOI Listing
January 2019
3 Reads

Anterior cervical discectomy and fusion can restore cervical sagittal alignment in degenerative cervical disease.

Eur J Orthop Surg Traumatol 2019 May 25;29(4):767-774. Epub 2019 Jan 25.

Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.

Objective: The purpose of this study was to evaluate its effect on the restoration and maintenance of cervical sagittal alignment in usual cervical degenerative diseases without preoperative sagittal malalignment.

Materials And Methods: We retrospectively evaluated 108 patients who were diagnosed with degenerative cervical disease and underwent ACDF (allograft and plating) with > 1-year follow-up. For radiographic evaluation, we analysed segmental and C2-7 cervical lordosis, disc height, C2-7 sagittal vertical axis (SVA), T1 slope, and T1 slope minus C2-7 lordosis (T1S - CL) in lateral X-ray. Read More

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http://dx.doi.org/10.1007/s00590-019-02386-7DOI Listing
May 2019
3 Reads

Motion response of a polycrystalline diamond adaptive axis of rotation cervical total disc arthroplasty.

Clin Biomech (Bristol, Avon) 2019 Feb 4;62:34-41. Epub 2019 Jan 4.

Edward Hines Jr. VA Hospital, Hines, IL, USA; Loyola University Medical Center, Maywood, IL, USA.

Background: Cervical fusion is associated with adjacent segment degeneration. Cervical disc arthroplasty is considered an alternative to reduce risk of adjacent segment disease. Kinematics after arthroplasty should closely replicate healthy in vivo kinematics to reduce adjacent segment stresses. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S02680033183070
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http://dx.doi.org/10.1016/j.clinbiomech.2018.12.023DOI Listing
February 2019
12 Reads

Artificial disc replacement versus fusion in patients with cervical degenerative disc disease and radiculopathy: a randomized controlled trial with 5-year outcomes.

J Neurosurg Spine 2019 Jan;30(3):323-331

1Department of Surgical Sciences, Uppsala University, Uppsala.

In BriefIn this study the authors compare cervical arthroplasty with fusion surgery in a randomized controlled trial using patient-reported outcome measures and MRI after 5 years of follow-up. Because the main purpose of arthroplasties is to prevent adjacent-segment pathology, it is important to investigate if that is actually realized in practice. Read More

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http://dx.doi.org/10.3171/2018.9.SPINE18659DOI Listing
January 2019
5 Reads

Spontaneous resolution and complete recovery of spontaneous cervical epidural hematoma: Report of two cases and literature review.

Neurochirurgie 2019 Feb 8;65(1):27-31. Epub 2019 Jan 8.

Department of Orthopaedics, Shanghai Changzheng Hospital, Second Military Medical University, No. 415, Feng Yang Street, Huangpu District, Shanghai 200003, China.

Objective: To present the natural course and treatment modalities of spontaneous cervical epidural hematoma (SCEH), by reporting two rare cases with spontaneous resolution in both clinical and radiologic findings without surgery.

Material And Methods: One patient presenting with acute right side hemiparesis and another showing pure cervical radiculopathy were diagnosed with SCEH on magnetic resonance imaging (MRI). Both were both treated non-operatively. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00283770183036
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http://dx.doi.org/10.1016/j.neuchi.2018.10.008DOI Listing
February 2019
17 Reads

Factors Associated with Return-to-Work following Cervical Spine Surgery in Non-Worker's Compensation Setting.

Spine (Phila Pa 1976) 2019 Jan 7. Epub 2019 Jan 7.

Department of Orthopaedic Surgery and Department of Neurological Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.

Study Design: This study retrospectively analyzes prospectively collected data.

Objective: Here in this study we aim to determine the factors which impact a patient's ability to RTW in the setting of cervical spine surgery in patients without worker's compensation status.

Summary Of Background Data: Surgical management of degenerative cervical disease has proven cost-effectiveness and shown significant improvement in quality of life. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002978DOI Listing
January 2019
12 Reads

Risk Factors for Rapidly Progressive Neurological Deterioration in Cervical Spondylotic Myelopathy.

Spine (Phila Pa 1976) 2019 Jan 4. Epub 2019 Jan 4.

Department of Orthopaedic Surgery, Gunma University Graduate School of Medicine, 3-39-22 Showa, Maebashi, Gunma, 371-8511, Japan.

Study Design: A retrospective single-center study.

Objective: This study sought to clarify the risk factors and to evaluate the surgical outcome in patients with rapidly progressive cervical spondylotic myelopathy (rp-CSM).

Summary Of Background Data: CSM is a degenerative spine disease presenting a slow development of myelopathy. Read More

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http://dx.doi.org/10.1097/BRS.0000000000002969DOI Listing
January 2019
3 Reads

Bilateral papillitis and vitritis as the initial ophthalmologic finding in a patient with complex medical history, leading to diagnosis of multisystem sarcoidosis.

Am J Ophthalmol Case Rep 2019 Mar 21;13:122-126. Epub 2018 Dec 21.

Massachusetts Eye Research and Surgery Institution (MERSI), 1440 Main Street, Suite 201, Waltham, MA, 02451, USA.

Aim: To report a case of bilateral papillitis as the initial ophthalmologic presentation in a patient with complex medical history and multisystemic symptoms, eventually revealing a diagnosis of sarcoidosis.

Methods: Retrospective interventional case report.

Report: A 54-year-old Caucasian woman presented with bilateral decreased vision, photophobia and eye pain for a month. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S24519936183024
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http://dx.doi.org/10.1016/j.ajoc.2018.12.020DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6322055PMC
March 2019
14 Reads

Evidence-based use of arthroplasty in cervical degenerative disc disease.

Int Orthop 2019 Apr 8;43(4):767-775. Epub 2019 Jan 8.

Department of Orthopedic Surgery, Columbia University, New York, NY, USA.

Introduction: Cervical disc arthroplasty (CDA) was developed to decrease the rate of symptomatic adjacent-level disease while preserving motion in the cervical spine.

Methods: The objectives of this paper are to provide criteria for proper patient selection as well as to present a comprehensive literature review of the current evidence for CDA, including randomized studies, the most recent meta-analysis findings, and long-term follow-up clinical trials as well.

Results: Currently, there are several prospective randomized controlled studies of level I of evidence attesting to the safety and efficacy of CDA in the management of cervical spondylotic disease (CSD) for one- or two-level degenerative diseases. Read More

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http://link.springer.com/10.1007/s00264-018-04281-y
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http://dx.doi.org/10.1007/s00264-018-04281-yDOI Listing
April 2019
12 Reads

Role of Subaxial Spinal and Atlantoaxial Instability in Multisegmental Cervical Spondylotic Myelopathy.

Authors:
Atul Goel

Acta Neurochir Suppl 2019;125:71-78

Department of Neurosurgery, Seth GS Medical College and KEM Hospital, Mumbai, India.

Aim: In this paper the role of atlantoaxial and multilevel subaxial spinal instability as the primary nodal point of the pathogenesis of degenerative cervical spinal disease-related myelopathy, and the focus of surgical treatment for it, is evaluated.

Materials And Methods: The series analyses the treatment of 73 patients with single or multilevel degenerative cervical spinal disease by fixation of the involved spinal segment(s) alone, aimed at arthrodesis. No bone decompression or disc/osteophyte resection was done. Read More

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http://dx.doi.org/10.1007/978-3-319-62515-7_11DOI Listing
January 2019
2 Reads

Characteristics of Cervical Sagittal Alignment at Different C0-C2 Correcting Angles in Fusion Treatment of Atlantoaxial Dislocations.

World Neurosurg 2018 Dec 21. Epub 2018 Dec 21.

Surgery of Spine and Spinal Cord, Henan Provincial People Hospital, Jinshui District, Zhengzhou, China. Electronic address:

Objective: To explore the appropriate range of C0-C2 correction angles by analyzing cervical sagittal alignment parameters and evaluating clinical outcomes.

Methods: The preoperative and postoperative radiographs, visual analogue scale, Japanese Orthopedic Association score, and neck disability index of 65 atlantoaxial dislocation patients were retrospectively collected. The C0-C2 angle, C2-C7 angle, and cervical sagittal vertical axis (cSVA) were measured from the radiographs, and an assessment of cervical degenerative disc disease was made. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.017DOI Listing
December 2018
9 Reads

Inborn Errors of Metabolism: Pseudoxanthoma Elasticum.

Adv Exp Med Biol 2018;1085:187-189

Department of Ophthalmology, Columbia University, Edward S. Harkness Eye Institute, NewYork-Presbyterian Hospital, New York, NY, USA.

Pseudoxanthoma elasticum (PXE) is an autosomal recessive multisystem disorder that involves the skin, GI tract, and heart, as well as the eye. It affects approximately 1 in 50,000 people worldwide and is seen twice as frequently in females as in males. Fundus findings include angioid streaks (Fig. Read More

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http://link.springer.com/10.1007/978-3-319-95046-4_38
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http://dx.doi.org/10.1007/978-3-319-95046-4_38DOI Listing
January 2018
12 Reads

Clinical Outcomes After Four-Level Anterior Cervical Discectomy and Fusion.

Global Spine J 2018 Dec 24;8(8):776-783. Epub 2018 Apr 24.

The Rothman Institute at Thomas Jefferson University, Philadelphia, PA, USA.

Study Design: Retrospective cohort study.

Objectives: Anterior cervical discectomy and fusion (ACDF) demonstrates reliable improvement in neurologic symptoms associated with anterior compression of the cervical spine. There is a paucity of data on outcomes following 4-level ACDFs. Read More

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http://dx.doi.org/10.1177/2192568218770763DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6293423PMC
December 2018
2 Reads

Therapeutic evaluation of acupoint stimulation with needle-scapelon on rat model of degenerative cervical intervertebral discs.

Biomed Pharmacother 2019 Feb 12;110:677-684. Epub 2018 Dec 12.

Department of Acupuncture, Qianfo Shan Hospital, Jinan, Shandong Province, 250014, China.

Cervical spondylosis (CS), which is resulted from degeneration of cervical intervertebral disc, is a common disease seriously threatening human health and quality of life. However, there is still no effective clinic strategies for the treatment of this disease. The acupoint stimulation with needle-scalpel is a widely used approach to treat orthopedic diseases. Read More

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http://dx.doi.org/10.1016/j.biopha.2018.11.070DOI Listing
February 2019
4 Reads

Trends in cervical disc arthroplasty and revisions in the Medicare database.

J Spine Surg 2018 Sep;4(3):522-528

East Coast Orthopedics, Pompano, FL, USA.

Background: Due to increased postoperative complications with anterior cervical discectomy and fusion (ACDF), there has been an increasing interest in the use of cervical disc arthroplasty (CDA). Advancements in prosthetic designs and techniques have improved patient reported outcome measurements and minimized revision rates. There is a paucity in the literature regarding recent trends in CDA utilization and revision rates. Read More

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http://dx.doi.org/10.21037/jss.2018.09.04DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6261747PMC
September 2018
4 Reads

The Option of Motion Preservation in Cervical Spondylosis: Cervical Disc Arthroplasty Update.

Neurospine 2018 Dec 14;15(4):296-305. Epub 2018 Dec 14.

Department of Neurosurgery, University of California, San Francisco, San Francisco, CA, USA.

Cervical disc arthroplasty (CDA), or total disc replacement, has emerged as an option in the past two decades for the management of 1- and 2-level cervical disc herniation and spondylosis causing radiculopathy, myelopathy, or both. Multiple prospective randomized controlled trials have demonstrated CDA to be as safe and effective as anterior cervical discectomy and fusion, which has been the standard of care for decades. Moreover, CDA successfully preserved segmental mobility in the majority of surgical levels for 5-10 years. Read More

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http://dx.doi.org/10.14245/ns.1836186.093DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347355PMC
December 2018
3 Reads

Cervical disc degeneration and neck pain.

J Pain Res 2018 14;11:2853-2857. Epub 2018 Nov 14.

Interventional Spine and Musculoskeletal Care, Virginia iSpine Physicians, PC Virginia Spine Research Institute, Inc Richmond, VA, USA.

Cervical intervertebral disc has long been considered a common source of neck pain. However, the pain caused by the disc itself has not been clearly defined so far, and its diagnosis and treatment has always been controversial. Degenerative cervical disc has a rich supply of nerve fibers, is prone to inflammatory reactions, and is susceptible to pain that can be provoked by disc stimulation or distention, and can be eliminated by block. Read More

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http://dx.doi.org/10.2147/JPR.S180018DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6241687PMC
November 2018
19 Reads

Comparison of Inpatient and Outpatient Preoperative Factors and Postoperative Outcomes in 2-Level Cervical Disc Arthroplasty.

Neurospine 2018 Dec 9;15(4):376-382. Epub 2018 Sep 9.

Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY, USA.

Objective: The purpose of this study was to evaluate factors associated with inpatient admission following 2-level cervical disc arthroplasty (CDA). A secondary aim was to compare outcomes between those treated on an inpatient versus outpatient basis.

Methods: Using data from the American College of Surgeons National Surgical Quality Improvement Program database, multivariate logistic regression analysis was used to assess the independent effect of each variable on inpatient or outpatient selection for surgery. Read More

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http://dx.doi.org/10.14245/ns.1836102.051DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6347354PMC
December 2018
2 Reads

Measurement of spinal cord atrophy using phase sensitive inversion recovery (PSIR) imaging in motor neuron disease.

PLoS One 2018 29;13(11):e0208255. Epub 2018 Nov 29.

Department of Neurology, University of California San Francisco, San Francisco, California, United States of America.

Background: The spectrum of motor neuron disease (MND) includes numerous phenotypes with various life expectancies. The degree of upper and lower motor neuron involvement can impact prognosis. Phase sensitive inversion recovery (PSIR) imaging has been shown to detect in vivo gray matter (GM) and white matter (WM) atrophy in the spinal cord of other patient populations but has not been explored in MND. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0208255PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6264489PMC
November 2018
18 Reads

Cost-Effectiveness Analysis of Cervical Anterior Fusion and Cervical Artificial Disc Replacement in the Korean Medical System.

J Korean Neurosurg Soc 2019 Jan 30;62(1):83-89. Epub 2018 Nov 30.

Department of Neurosurgery, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.

Objective: This study is a retrospective cost-benefit analysis of cervical anterior interbody fusion and cervical artificial disc replacement, which are the main surgical methods to treat degenerative cervical disc disease.

Methods: We analyzed 156 patients who underwent anterior cervical disc fusion and cervical artificial disc replacement from January 1, 2008 to December 31, 2009, diagnosed with degenerative cervical disc disorder. In this study, the costs and benefits were analyzed by using quality adjusted life year (QALY) as the outcome index for patients undergoing surgery, and a Markov model was used for the analysis. Read More

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http://jkns.or.kr/journal/view.php?doi=10.3340/jkns.2018.007
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http://dx.doi.org/10.3340/jkns.2018.0076DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6328803PMC
January 2019
7 Reads

Artificial disc replacement versus fusion in patients with cervical degenerative disc disease with radiculopathy: 5-year outcomes from the National Swedish Spine Register.

J Neurosurg Spine 2018 11;30(2):159-167

Department of Surgical Sciences, Uppsala University, Uppsala.

OBJECTIVE: The long-term efficacy of artificial disc replacement (ADR) surgery compared with fusion after decompression for the treatment of cervical degenerative disc disease and radiculopathy has not previously been investigated in a population-based setting. METHODS: All patients with cervical degenerative disc disease and radiculopathy who were in the national Swedish Spine Registry (Swespine) beginning in January 1, 2006, were eligible for the study. Follow-up information was obtained up to November 15, 2017. Read More

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http://dx.doi.org/10.3171/2018.7.SPINE18657DOI Listing
November 2018
4 Reads

Stand-Alone Cervical Cages in 2-Level Anterior Interbody Fusion in Cervical Spondylotic Myelopathy: Results from a Minimum 2-Year Follow-up.

Asian Spine J 2019 Apr 27;13(2):225-232. Epub 2018 Nov 27.

Department of Orthopaedics and Traumatology, Kwong Wah Hospital, Hong Kong.

Study Design: A retrospective review of patients who underwent 2-level anterior cervical discectomy and fusion (ACDF) with standalone polyetheretherketone (PEEK) cages for cervical spondylotic myelopathy (CSM).

Purpose: To evaluate the efficacy of stand-alone PEEK cage in 2-level cervical interbody fusion for CSM.

Overview Of Literature: ACDF is a standard surgical procedure to treat degenerative disc disease. Read More

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http://dx.doi.org/10.31616/asj.2018.0193DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6454285PMC
April 2019
3 Reads

Adjacent segment degeneration after fusion spinal surgery-a systematic review.

Int Orthop 2019 Apr 23;43(4):987-993. Epub 2018 Nov 23.

Department of Orthopaedic Surgery, Tohoku University Graduate School of Medicine, 1-1 Seiryo-machi, Aoba-ku, Sendai, Miyagi, 980-8574, Japan.

Purpose: Adjacent segment degeneration (ASDeg) and disease (ASDis) have become major concerns after fusion surgery. However, there is no definitive data or knowledge about the incidence or risk factors. The review discusses the incidence and risk factors and prevention of ASDeg and ASDis in the relevant literature. Read More

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http://dx.doi.org/10.1007/s00264-018-4241-zDOI Listing
April 2019
29 Reads

Pediatric Idiopathic Intervertebral Disc Calcification: Single-Center Series and Review of the Literature.

J Pediatr 2019 Mar 19;206:212-216. Epub 2018 Nov 19.

Division of Neurosurgery, The Hospital for Sick Children, University of Toronto, Toronto, Ontario, Canada.

Objective: To review pediatric idiopathic intervertebral disc calcification (PIIVDC) within a single center and within the literature to outline the disease course, management, and outcome.

Study Design: A retrospective chart review was performed spanning the period between January 2001 and February 2016 for diagnoses of PIIVDC. Patient age, sex, symptoms, and history and physical and neurologic findings were reviewed. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00223476183156
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http://dx.doi.org/10.1016/j.jpeds.2018.10.058DOI Listing
March 2019
22 Reads

Granulomatous Reaction on a Double-Level Cervical Total Disc Arthroplasty.

World Neurosurg 2019 Feb 17;122:360-363. Epub 2018 Nov 17.

Department of Neurosurgery, Saint-Luc Hospital, Université Catholique de Louvain, Brussels, Belgium. Electronic address:

Background: Cervical total disc arthroplasty (TDA), or cervical artificial disc replacement, is an alternative technique to anterior cervical discectomy and fusion for treatment of symptomatic degenerative cervical spine disease. The main goal of TDA is to maintain cervical motion and lower the risk of deterioration of adjacent levels. Granuloma formation on a cervical TDA is exceptional. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183261
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http://dx.doi.org/10.1016/j.wneu.2018.11.070DOI Listing
February 2019
22 Reads

Patient-Reported Outcomes and Patient-Reported Satisfaction After Surgical Treatment for Cervical Radiculopathy.

Global Spine J 2018 Oct 19;8(7):703-708. Epub 2018 Apr 19.

Hospital Lillebælt, Middelfart, Denmark.

Study Design: Retrospective cohort study.

Objectives: It is estimated that 10 000 patients seek medical care due to cervical radiculopathy every year in Denmark. Although the natural course is usually favorable, around 20% undergo surgery for cervical degenerative disease every year in Denmark. Read More

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http://dx.doi.org/10.1177/2192568218765398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6232721PMC
October 2018
10 Reads

A Comparison of Cervical Disc Arthroplasty and Anterior Cervical Discectomy and Fusion in Patients with Two-Level Cervical Degenerative Disc Disease: 5-Year Follow-Up Results.

World Neurosurg 2019 Feb 9;122:e1083-e1089. Epub 2018 Nov 9.

Department of Operation Room, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Objective: To present a long-term clinical and radiographic comparison between the Prestige LP cervical disc replacement and the Zero-P spacer cervical disc fusion in the treatment of patients with symptomatic 2-level cervical degenerative disease.

Methods: In total, 36 patients in the anterior cervical discectomy and fusion (ACDF) group and 24 patients in the cervical disc arthroplasty (CDA) group were analyzed before surgery and at 1 week and 3, 6, 12, 24, and 60 months after surgery. Clinical assessments included the Japanese Orthopaedic Association score, visual analog scale, and Neck Disability Index scores. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S18788750183253
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http://dx.doi.org/10.1016/j.wneu.2018.10.231DOI Listing
February 2019
9 Reads