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Complement Ther Med 2020 May 6;50:102392. Epub 2020 Apr 6.

Centre for Evidence Based Chinese Medicine, Beijing University of Chinese Medicine, Beijing, 100029, China; Institute of Integrated Traditional Chinese Medicine and Western Medicine, Guangzhou Medical University, Guangzhou, China. Electronic address:

Objective: This bibliometric study aimed to systematically and comprehensively summarize the volume, breadth and evidence for clinical research on Qigong. And this bibliometric analysis also can provide the evidence of this field.

Design: Bibliometric analysis. Read More

Comput Biol Med 2020 May 18;120:103760. Epub 2020 Apr 18.

Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430022, China. Electronic address:

Anterior cervical discectomy and fusion (ACDF) is a well-established surgical treatment for patients with symptomatic cervical degenerative disc disease, while the biomechanical changes of adjacent segments after ACDF using either a zero-profile device or cage plus plate remain uncertain. The present study is to compare adjacent segment biomechanical changes after one- or two-level ACDF using either a zero-profile device or cage plus plate. A three-dimensional finite element (FE) intact cervical model (C2-C7) was constructed and validated. Read More

Cureus 2020 Apr 12;12(4):e7643. Epub 2020 Apr 12.

Orthopaedics, King Abdulaziz Medical City, Ministry of National Guard Health Affairs, Riyadh, SAU.

Background Anterior cervical discectomy and fusion (ACDF) is a commonly used procedure. However, few studies reported post-operative complications. This study looks into the prevalence of possible complications and the mortality rate in the first 30 days postoperatively. Read More

Foot Ankle Spec 2020 May 12:1938640020917782. Epub 2020 May 12.

St Luke's University Health Network, Quakertown, Pennsylvania (JRL).

Ankle arthritis is a major cause of disability. Orthopaedic literature suggests improvement in health-related quality of life (HRQOL) after total ankle arthroplasty (TAA). This has not been compared with improvements observed in successful orthopaedic and nonorthopaedic procedures, including anterior cervical discectomy/fusion (ACDF), total knee arthroplasty (TKA), coronary artery bypass grafting (CABG), and orthotopic liver transplant (OLT). Read More

BMC Neurol 2020 May 11;20(1):175. Epub 2020 May 11.

Anesthesia Department, CIMA Hospital, Barcelona, Spain.

Background: We propose two new concepts, the Filum Disease (FD) and the Neuro-cranio-vertebral syndrome (NCVS), that group together conditions thus far considered idiopathic, such as Arnold-Chiari Syndrome Type I (ACSI), Idiopathic Syringomyelia (ISM), Idiopathic Scoliosis (IS), Basilar Impression (BI), Platybasia (PTB) Retroflexed Odontoid (RO) and Brainstem Kinking (BSK).

Method: We describe the symptomatology, the clinical course and the neurological signs of the new nosological entities as well as the changes visible on imaging studies in a series of 373 patients.

Results: Our series included 72% women with a mean age of 33. Read More

Medicine (Baltimore) 2020 May;99(19):e20143

Department of Orthopedics, Tianjin Fifth Central Hospital, Tianjin, China.

Study Design: The present study was conducted following the Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) statement.

Objective: The present study aimed to conduct a systematic review of overlapping meta-analyses comparing ACDR with fusion for treating CDDD in order to assist decision makers in their selection among conflicting meta-analyses and to provide treatment recommendations based on the best available evidence.

Summary Of Background Data: Although several meta-analyses have been performed to compare total disc replacement (TDR) and fusion for treating cervical degenerative disc disease (CDDD), their findings are inconsistent. Read More

World Neurosurg 2020 May 1. Epub 2020 May 1.

University Clinic Düsseldorf, Med Fac, Department of Neurosurgery, Germany. Electronic address:

Objectives: Conventional surgical treatment of multi-level cervical disc disease is based on anterior cervical discectomy and fusion (ACDF). However, fusion alters the biomechanics of the spine, resulting in potential accelerated adjacent segment degeneration. To improve clinical outcomes, hybrid surgery, combining cervical disc arthroplasty with fusion, has been developed. Read More

J Pain Res 2020 21;13:771-776. Epub 2020 Apr 21.

Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an 710054, Shaanxi Province, People's Republic of China.

Objective: To report a rare case of spontaneous fusion (SF) following cervical disc arthroplasty (CDA), to review the related literature, and to propose a new measure to prevent it.

Methods: The course of a patient with SF is described here. The potential causes, risk factors, and preventive measure of SF after CDA published in previous studies have also been reviewed and discussed. Read More

J Neurosurg Spine 2020 May 1:1-8. Epub 2020 May 1.

1Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital.

Objective: Cigarette smoking has been known to increase the risk of pseudarthrosis in spinal fusion. However, there is a paucity of data on the effects of smoking in dynamic stabilization following lumbar spine surgery. This study aimed to investigate the clinical outcomes and the incidence of screw loosening among patients who smoked. Read More

Spine (Phila Pa 1976) 2020 Apr 24. Epub 2020 Apr 24.

The Mount Sinai Hospital Spine Center, New York, NY.

Study Design: Systematic Review.

Objectives: The purpose of the current study is to determine the overall incidence of HO following CDA as well as per annum rates.

Summary Of Background Data: CDA is a well-established surgical modality for treatment of one- and two-level degenerative disc disease that has failed conservative treatment. Read More

Rev Bras Ortop (Sao Paulo) 2020 Apr 19;55(2):185-190. Epub 2019 Dec 19.

Serviço de Ortopedia, Centro Hospitalar de São João, Porto, Portugal.

 In the present study, we present the results with at least 10 years of follow-up of the cervical disc prosthesis implanted in a single level.  Retrospective study of patients undergoing single-level total cervical disc replacement (TCDR). Clinical results included the neck disability index (NDI) and the visual analogue scale (VAS) in the preoperative period, one year postoperatively, and a minimum of 10 years of follow-up. Read More

J Mech Behav Biomed Mater 2020 Jun 22;106:103735. Epub 2020 Mar 22.

Center for NeuroTrauma Research, Department of Neurosurgery, Medical College of Wisconsin, Milwaukee, WI, USA.

Surgical treatment for spinal disorders, such as cervical disc herniation and spondylosis, includes the removal of the intervertebral disc and replacement of biological or artificial materials. In the former case, bone graft is used to fill the space, and this conventional procedure is termed anterior cervical discectomy and fusion (ACDF). The latter surgery is termed as artificial disc replacement ADR) or cervical disc arthroplasty (CDA). Read More

Global Spine J 2020 May 23;10(3):294-302. Epub 2019 May 23.

Sint Maartenskliniek, Nijmegen, the Netherlands.

Study Design: Prospective cohort study.

Objective: To investigate the primary stability of the Prodisc-C Vivo cervical disc arthroplasty with regard to the adjacent cervical vertebrae using radiostereometric analysis (RSA), and to monitor its clinical performance.

Methods: Sixteen patients with degenerative cervical disc disease were included. Read More

BMC Neurol 2020 Apr 20;20(1):143. Epub 2020 Apr 20.

Department of Orthopedics, The First Affiliated Hospital of Soochow University, 899, Pinghai Road, Suzhou, 215006, China.

Background: This meta-analysis was designed to investigate the long-term efficacy and safety between cervical disc arthroplasty (CDA) and anterior cervical discectomy and fusion (ACDF) in treating cervical disc degenerative diseases (CDDDs).

Methods: Literature search was performed on Pubmed, Embase, Cochrane Library, and Web of Science before Jan 2019. Surgical details, clinical outcomes, range of motion (ROM), complications, and reoperation rates between CDA and ACDF groups were compared and analyzed. Read More

J Spine Surg 2020 Mar;6(1):233-242

Department of Neurosurgery, Centro Hospitalar de Vila Nova de Gaia, Espinho, Portugal.

Background: Cervical disc arthroplasty (CDA) is a valid option for single-level cervical disc disease (CDD) as an alternative to fusion. However, the use in 3- and 4-level disc disease is under scrutiny with scarce data published so far. Our aim was to study clinical and radiological outcomes of arthroplasty in patients with multilevel CDD. Read More

Orthop Surg 2020 Apr 14. Epub 2020 Apr 14.

Department of Spine Surgery, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, China.

Objective: To compare the efficacy and safety of the postoperative long-term effect of the treatment of single-level cervical spondylosis through anterior cervical discectomy and fusion (ACDF) and artificial cervical disc replacement (ACDR).

Methods: This is a retrospective contrastive study, which was conducted for the period of January 2007 and January 2009 at the Department of Spine Surgery of the First Affiliated Hospital of Xinjiang Medical University. A total of 113 patients were divided into two groups depending on the operation method: ACDF group (fusion group, n = 66) and ACDR group (replacement group, n = 47). Read More

Spine J 2020 Apr 8. Epub 2020 Apr 8.

Department of Neurosurgery, Helsinki University Hospital, Helsinki, Finland. Electronic address:

Background Context: Anterior cervical discectomy and fusion (ACDF) procedures is thought to lead to accelerated degeneration of the adjacent cervical discs and in some cases can be symptomatic (adjacent segment disease, or ASD). The occurrence of ASD is of particular interest when treating young individuals, as the cumulative disease burden may become increasingly significant during their expectedly long lifetime. However, the overall impact of a surgical intervention on the lifetime prognosis of ASD remains unclear. Read More

Case Rep Orthop 2020 23;2020:3439403. Epub 2020 Mar 23.

Department of Orthopedic Surgery, Japanese Red Cross Narita Hospital, 90-1, Iidacho, Narita-shi, Chiba 286-8523, Japan.

We encountered two cases of cervical disc herniation, wherein cerebrospinal fluid collection in the ventral epidural space between the cervical spine and the thoracic spine was noted. The patients, two women aged 71 and 43 years, were diagnosed with cervical disc herniation and underwent anterior cervical discectomy and fusion. Unexpected cerebrospinal fluid leakage was observed prior to exposure of the dura mater. Read More

J Spine Surg 2020 Jan;6(Suppl 1):S208-S223

Department of Orthopaedics, University of British Columbia, Vancouver, BC, Canada.

Background: Minimally invasive spine surgery (MISS) and endoscopic spine surgery have continually evolving indications in the cervical, thoracic, and lumbar spine. Endoscopic spine surgery entails treatment of disc disease, stenosis, spondylolisthesis, radiculopathy, and deformity. MISS involves complex motor skills in regions of variable anatomy. Read More

Front Bioeng Biotechnol 2020 4;8:154. Epub 2020 Mar 4.

Department of Orthopedics, National Cheng Kung University Hospital, College of Medicine, National Cheng Kung University, Tainan, Taiwan.

Hybrid surgery (HS) allows surgeons to tailor fusion and arthroplasty in the treatment of multiple-level cervical disc degeneration. However, the decision making of selecting either ACDF or ADR for each level in three-level HS remains controversial and has not been fully investigated. This study was aimed to optimize three-level cervical hybrid constructs by systematically investigating their biomechanical properties and their effect on adjacent levels. Read More

J Orthop Res 2020 Mar 11. Epub 2020 Mar 11.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, Illinois.

Degenerative spine imaging findings have been extensively studied in the lumbar region and are associated with pain and adverse clinical outcomes after surgery. However, few studies have investigated the significance of these imaging "phenotypes" in the cervical spine. Patients with degenerative cervical spine pathology undergoing anterior cervical discectomy and fusion (ACDF) from 2008 to 2015 were retrospectively and prospectively assessed using preoperative MRI for disc degeneration, narrowing, and displacement, high-intensity zones, endplate abnormalities, Modic changes, and osteophyte formation from C2-T1. Read More

Clin Spine Surg 2020 Mar 6. Epub 2020 Mar 6.

Indiana Spine Group, Indianapolis, IN.

Study Design: A retrospective review of a prospective, randomized control Food and Drug Administration (FDA) investigational device exemption trial comparing anterior cervical discectomy and fusion (ACDF) with Bryan cervical disc arthroplasty.

Objective: Determine the clinical significance of adjacent-level ossification disease (ALOD) on long-term functional outcomes after ACDF or arthroplasty.

Summary Of Background Data: ALOD occurs when the anterior longitudinal ligament and annulus adjacent to the index surgical level calcifies. Read More

Int J Spine Surg 2020 Feb 29;14(1):79-86. Epub 2020 Feb 29.

Department of Orthopaedics, NYU Langone Orthopedic Hospital, New York, New York.

Background: Hospital-acquired venous thromboembolisms (HA-VTE) are a significant source of morbidity and mortality in spine surgery patients. The purpose of this study was to review HA-VTE rates at our institution and evaluate the prevalence of known risk factors in patients who developed HA-VTE among both neurosurgical and orthopedic spine surgeries.

Methods: Retrospective chart reviews were conducted of all spine surgery patients from January 1, 2013, to July 31, 2017, to evaluate rates of HA-VTE and prevalence of known HA-VTE risk factors among these patients. Read More

Spine (Phila Pa 1976) 2020 Feb 24. Epub 2020 Feb 24.

Department of Orthopaedic Surgery, Rush University Medical Center, Chicago, IL, USA.

Study Design: Retrospective cohort OBJECTIVE.: To determine how type, location, and size of endplate lesions on magnetic resonance imaging (MRI) may be associated with symptomatology and clinical outcomes after ACDF.

Summary Of Background Data: Structural endplate abnormalities are important phenomena that remain understudied in the cervical spine. Read More

Tuberk Toraks 2019 Dec;67(4):285-291

Department of Occupational Diseases, Faculty of Medicine, Dokuz Eylul University, Izmir, Turkey.

Introduction: We aimed to evaluate the diagnosis of patients who applied on the first three years of our clinic, in order to contribute to the state of occupational diseases (OD) in Turkey.

Materials And Methods: The study is a cross-sectional study, between November 2013 and December 2016, 862 subjects were accepted for the evaluation. Gender, age, application ways, the reason of referral, workplace, exposure time and possible risks for the patients were evaluated through a file examination. Read More

Asian Spine J 2020 Feb 14. Epub 2020 Feb 14.

NeuroSpine Surgery Research Group, Sydney, Australia.

Anterior cervical discectomy and fusion (ACDF) immobilizes surgical segments and can lead to the development of adjacent segment degeneration and adjacent segment disease. Thus, cervical total disc replacement (CTDR) has been developed with the aim to preserve the biomechanics of spine. However, heterotopic ossification (HO), a complication following CTDR, can reduce the segmental range of motion (ROM) and defects the motion-preservation benefit of CTDR. Read More

Medicine (Baltimore) 2020 Feb;99(7):e19266

Department of Orthopedics, Korea University Ansan Hospital, Ansan.

Despite many clinical trials on cervical epidural steroid injections, the indications for and long-standing outcomes of this treatment remain controversial. We evaluated the outcomes and indications for transforaminal cervical epidural steroid injection (TCESI) in patients with moderate to severe disability.We prospectively gathered data from patients with 1 or 2-level cervical degenerative disease (herniated disc, foraminal stenosis) with moderate to severe disability (3. Read More

Oper Neurosurg (Hagerstown) 2020 Feb 10. Epub 2020 Feb 10.

Department of Neurosurgery, University of Michigan, Ann Arbor, Michigan.

Bow hunter syndrome is defined as vertebrobasilar insufficiency due to mechanical occlusion of the vertebral artery during head and neck rotation. In many cases, this is due to osteophyte formation, disc herniation, cervical spondylosis, tendinous bands, or tumors. Symptomatic disease may vary from inducing transient vertigo to posterior circulation stroke. Read More

J Spine Surg 2019 Dec;5(4):584-588

Department of Neurosurgery, St Vincent's Private Hospital, Sydney, NSW, Australia.

Cervical disc replacements are commonly used to treat degenerative disc disease. We present a case an M6-C disc replacement failure associated with infection three years post implantation. Read More

J Spine Surg 2019 Dec;5(4):393-403

NeuroSpine Surgery Research Group (NSURG), The University of New South Wales, Sydney, NSW, Australia.

Background: Cervical total disc replacement (CTDR) is complicated by adjacent segment degeneration (ASD). Since non-physiological spine kinematics after CTDR was postulated to cause ASD, M6-C prosthesis has been developed to better replicate the natural kinematics of the intervertebral disc. This retrospective cohort study aims to compare the short-term outcomes between patients receiving either the M6-C or Mobi-C prostheses. Read More

Aust Vet J 2020 Apr 9;98(4):156-163. Epub 2020 Feb 9.

Veterinary Specialist Services - Small Animal Surgery Department, Gold Coast, Queensland, Australia.

Objective: To assess the short- and long-term outcome of an anchored intervertebral titanium device (C-LOX) for the treatment of 10 dogs with disc-associated cervical spondylomyelopathy (DACSM) and 1 dog with osseous-associated cervical spondylomyelopathy.

Design: Retrospective case series.

Methods: Dogs were included if they were diagnosed with either DACSM or osseous-associated cervical spondylomyelopathy via myelography with or without advanced imaging and underwent surgical distraction and stabilisation of the affected intervertebral disc with a C-LOX implant. Read More

Zh Vopr Neirokhir Im N N Burdenko 2019 ;83(6):100-110

Burdenko Neurosurgical Center, Moscow, Russia.

Aim: The study aim was to perform a meta-analysis based on the results of randomized clinical trials comparing long-term outcomes of total intervertebral disc arthroplasty (TA) and anterior cervical spinal fusion (ACSF) in the surgical treatment of cervical degenerative disc disease.

Material And Methods: We searched Pubmed, EMBASE, ELibrary, and Cochrane Library databases for randomized clinical trials reported between 2008 and August 2018. The relative risk and 95% confidence interval were calculated for dichotomous variables; for continuous variables, we used the standardized mean difference and their 95% CI with application of a random effects model. Read More

Zhongguo Xiu Fu Chong Jian Wai Ke Za Zhi 2020 Feb;34(2):151-156

Department of Spine Surgery, Honghui Hospital Affiliated to Medical School of Xi'an Jiaotong University, Xi'an Shaanxi, 710054, P.R.China.

Objective: To compare differences in the maintenance of cervical curvature after anterior cervical surgery between zero-profile and self-locking intervertebral cage and plate-cage construct (PCC).

Methods: A clinical data of 100 patients with single-segment cervical disc herniation who were treated with anterior cervical discectomy and fusion were retrospectively analyzed between January 2015 and January 2016. Among them, 50 patients were treated with the zero-profile and self-locking intervertebral cage (group A) and 50 patients with the PCC (group B). Read More

J Orthop Surg Res 2020 Jan 31;15(1):36. Epub 2020 Jan 31.

Department of Orthopaedics, Xuanwu Hospital Capital Medical University, Beijing, 100053, China.

Background: Biomechanical characteristics of noncontinuous ACDF and noncontinuous CDA in the treatment of noncontinuous cervical degenerative disc disease were still unclear. The aim of this research is to compare the differences between these two kinds of treatment methods and to verify the effectiveness of Prodisc-C in noncontinuous CDA.

Methods: Eight FEMs of the cervical spine (C2-C7) were built based on CT images of 8 mild CDDD volunteers. Read More

Medicine (Baltimore) 2020 Jan;99(5):e19055

From the Department of acupuncture and moxibustion, Linyi people hospital, Linyi City, Shandong Province (FM), department of spine surgery, Yantai mountain hospital, Yantai city, Shandong provinceGU (YD), Thyroid breast surgery, Zhongshan university first affiliated hospital, Guangdong province (JL), and Department of Bone Tumor, Yantishan Hospital, Yantai, Shandong Province, PR China (JH).

To investigate the outcomes and reliability of hybrid surgery (HS) versus anterior cervical discectomy and fusion (ACDF) for the treatment of multilevel cervical spondylosis and disc diseases.Hybrid surgery, combining cervical disc arthroplasty (CDA) with fusion, is a novel treatment to multilevel cervical degenerated disc disease in recent years. However, the effect and reliability of HS are still unclear compared with ACDF. Read More

Front Bioeng Biotechnol 2019 14;7:437. Epub 2020 Jan 14.

Department of Materials, Faculty of Science and Engineering, The University of Manchester, Manchester, United Kingdom.

Treatments to alleviate chronic lower back pain, caused by intervertebral disc herniation as a consequence of degenerate annulus fibrosus (AF) tissue, fail to provide long-term relief and do not restore tissue structure or function. The future of AF tissue engineering relies on the production of its complex structure assisted by the many cells that are resident in the tissue. As such, this study aims to mimic the architecture and mechanical environment of outer AF tissue using electrospun fiber scaffolds made from a synthetic biopolymer blend of poly(ε-caprolactone) (PCL) and poly(L-lactic) acid (PLLA). Read More

J Clin Neurosci 2020 Apr 23;74:47-54. Epub 2020 Jan 23.

Department of Neurosurgery, Osaka City University Graduate School of Medicine, Osaka, Japan. Electronic address:

This multicenter prospective study investigated cage subsidence in anterior cervical discectomy and fusion (ACDF) using titanium-coated polyetheretherketone (PEEK) stand-alone cages. This study recruited patients who underwent 1- or 2-level ACDF using titanium-coated PEEK stand-alone cages for cervical disc disease. Patients with acute trauma or past cervical spine operations were excluded. Read More

Br J Neurosurg 2020 Jan 24:1-4. Epub 2020 Jan 24.

Department of Neurosurgery, Royal Victoria Infirmary, Newcastle upon Tyne, UK.

Cervical disc replacement is an alternative option to an anterior cervical discectomy and fusion for cervical spine degenerative disease. We present the first reported case of a progressively worsening symptomatic spinal cord compression secondary to migration of the nucleus from a Mobi-C total disc replacement. Read More

World J Clin Cases 2020 Jan;8(1):38-45

Third Ward of Orthopedics Department, Qilu Hospital, Shandong University, Jinan 250012, Shandong Province, China.

Background: Total cervical artificial disc replacement (TDR) has been considered a safe and effective alternative surgical treatment for cervical spondylosis and degenerative disc disease that have failed to improve with conservative methods. Positioning the surgical patient is a critical part of the procedure. Appropriate patient positioning is crucial not only for the safety of the patient but also for optimizing surgical exposure, ensuring adequate and safe anesthesia, and allowing the surgeon to operate comfortably during lengthy procedures. Read More

Int J Spine Surg 2019 Dec 31;13(6):551-560. Epub 2019 Dec 31.

SPIRITT Research, St Louis, Missouri.

Background: Anterior cervical discectomy and fusion (ACDF) and cervical disc arthroplasty (CDA) have been used to treat degenerative disc disease at single as well as multiple cervical levels. This study compares the safety and efficacy of 1-level versus 2-level CDA and ACDF.

Methods: In total, 545 and 397 patients with degenerative disc disease were studied in 1-level and 2-level Food and Drug Administration (FDA)-approved clinical trials, respectively: CDA (n = 280 and 209), ACDF (n = 265 and 188). Read More

Int J Spine Surg 2019 Dec 31;13(6):491-500. Epub 2019 Dec 31.

Department of Orthopaedics and Rehabilitation, University of Iowa Hospitals and Clinics, The University of Iowa, Iowa City, Iowa.

Background: Discectomy and fusion is considered the "gold standard" treatment for clinical manifestations of degenerative disc disease in the cervical spine. However, clinical and biomechanical studies suggest that fusion may lead to adjacent-segment disease. Cervical disc arthroplasty preserves the motion at the operated level and may potentially decrease the occurrence of adjacent segment degeneration. Read More

BMC Musculoskelet Disord 2020 Jan 20;21(1):45. Epub 2020 Jan 20.

Department of Radiology, Boston University School of Medicine, 820 Harrison Avenue, FGH Building 3rd Floor, Boston, MA, 02118, USA.

Objective: To describe the frequency and the distribution of degenerative disc disease (DDD) detected in athletes who underwent spine MRI in the 2016 Summer Olympic Games in Rio de Janeiro.

Methods: Data on spine MRI examinations from the 2016 Summer Olympics were retrospectively analyzed. We assessed the frequency of DDD of the cervical (Cs), thoracic (Ts), and lumbar (Ls) spine using Pfirrmann's classification. Read More

J Biomech 2020 Feb 7;100:109608. Epub 2020 Jan 7.

Department of Trauma Surgery, Orthopaedics and Plastic Surgery, University of Göttingen, Robert-Koch-Str. 40, 37075 Göttingen, Germany; DUO - Duderstadt Trauma Surgery and Orthopaedics, Westertorstr. 7, 37115 Duderstadt, Germany. Electronic address:

Total disc arthroplasty (TDA) increases the risk of adjacent segment disease (ASD). Kinematic analyses are necessary to compare the intact condition (IC) with alterations after TDA to develop better prostheses. A well-established 6D measuring apparatus (resolution < 2. Read More

World Neurosurg 2020 May 8;137:443-450.e13. Epub 2020 Jan 8.

Mayo Clinic Neuro-Informatics Laboratory, Mayo Clinic, Rochester, Minnesota, USA; Department of Neurologic Surgery, Mayo Clinic, Rochester, Minnesota, USA. Electronic address:

Background: There have been several clinical trials as well as observational studies that have compared the outcomes of different cervical disc replacement (CDR) devices with anterior cervical disc replacement and fusion (ACDF). Although the results of these studies have provided sufficient evidence for the safety of CDR, there is still a lack of consensus in terms of longer-term outcomes, with studies providing equivocal results for the 2 procedures. In the current study, we used a novel methodology, a meta-epidemiologic study, to investigate the impact of study characteristics on the observed effects in the literature on CDR and ACDF. Read More

JBI Database System Rev Implement Rep 2020 Jan 8. Epub 2020 Jan 8.

Laboratoire IRISSE, Université de La Réunion, Tampon, France.

Objective: The objective of this systematic review is to assess the evidence of association of cervical spine signs and symptoms with temporomandibular disorders (TMD). This will help to lend credence to mechanisms supporting the association, in order to improve care strategies for this condition.

Introduction: The association of cervical spine impairments (in relation to neck posture, cervical spine mobility, muscle tenderness, muscle activity and neck disability) with TMD has been widely discussed in the literature. Read More

Eur Spine J 2020 Feb 8;29(Suppl 1):57-65. Epub 2020 Jan 8.

Orthopedic Spinal Surgery Unit 1, Pellegrin Hospital, Place Amélie Raba-Léon, 33076, Bordeaux Cedex, France.

Introduction: Dynamic stabilization of the spine has been performed since the 1990s with the double purpose of restoring spinal segmental stability and allowing residual movement at the operated level. When we take into account the different motion-preserving devices and the spinal areas where they are applied, we can identify three categories of spinal implants: anterior cervical, anterior lumbar, and posterior lumbar. However, as in all prosthetic procedures performed in orthopedic surgery, the life span of a joint replacement device is a central topic of discussion, and this is true also for spinal dynamic devices, being revision surgery a complex procedure in specific cases. Read More

Vet Radiol Ultrasound 2020 May 3;61(3):353-363. Epub 2020 Jan 3.

Department of Clinical Sciences, Mississippi State University College of Veterinary Medicine, Mississippi State, Mississippi.

Cervical spinal disorders can lead to life-threatening respiratory complications. Diaphragmatic dysfunction is attributed to spinal cord morbidity secondary to cervical myelopathy or decompressive surgical intervention. The purpose of this observational case-control study was to determine the frequency of diaphragmatic dysfunction in dogs with cervical spinal disorders and a control group, the strength of association between cervical myelopathies and decompressive surgery with diaphragm paresis, and the agreement between and clinical usefulness of fluoroscopy, motion-mode ultrasonography, and radiography for diagnosing diaphragmatic dysfunction. Read More

Cureus 2019 Nov 26;11(11):e6239. Epub 2019 Nov 26.

Emergency Medicine, Thomas Jefferson University Hospital, Philadelphia, USA.

Calcium pyrophosphate dihydrate (CPPD) crystal deposition disease or pseudogout is an idiopathic articular disease that predominantly affects elderly patients. It is caused by a systemic deposition of calcium pyrophosphate (CPP) crystals in the articular and hyaline joint cartilage. The majority of cases present as chronic arthritis, but a subset of CPPD can present as rapid onset of sharp pain and joint swelling, posing a diagnostic challenge. Read More

Orthop Surg 2020 Feb 21;12(1):16-30. Epub 2019 Dec 21.

Department of Spine Surgery, The Second Xiangya Hospital of Central South University, Changsha, China.

Objective: Whether cervical disc arthroplasty (CDA) is superior to anterior cervical discectomy and fusion (ACDF) remains controversial, especially in relation to long-term results. The present study aimed to evaluate the long-term safety and efficiency of CDA and ACDF for cervical disc disease.

Methods: We performed this study according to the Cochrane methodology. Read More

Acta Neurochir (Wien) 2020 02 17;162(2):289-303. Epub 2019 Dec 17.

Edinburgh Spinal Surgery Outcomes Study Group, Edinburgh, UK.

Background: Multilevel cervical degenerative disc disease (CDDD) can be treated surgically with anterior cervical discectomy and fusion (ACDF), cervical disc arthroplasty (CDA), or a hybrid surgery (HS) of the two in which both procedures are used at different vertebral levels. A systematic review and meta-analysis was performed to compare the clinical and radiographical outcomes of HS against ACDF or CDA alone.

Methods: Three electronic databases were searched for articles published before December 2018. Read More