523,318 results match your criteria Cervical Cancer
Aktuelle Urol 2018 Dec 6;49(6):519-524. Epub 2018 Dec 6.
Spital Thurgau AG, Urologie, Frauenfeld.
The classical algorithm of the management of male lower urinary tract symptoms (LUTSs) due to benign prostatic hyperplasia (BPH) includes a surgical approach in case pharmacological therapy has failed. Emerging minimally-invasive treatments (MITs) offer potential for rapid symptomatic relief, reducing the morbidity of invasive BPH surgery. Convective interstitial radiofrequency water vapour thermal ablation of the prostate with the Rezūm system is a novel MIT for the treatment of bothersome moderate-to-severe lower urinary tract symptoms associated with BPH. Read More
Semin Neurol 2018 Dec 6;38(6):634-639. Epub 2018 Dec 6.
Department of Neurology, Boston University School of Medicine, Boston University Medical Center, Boston, Massachusetts.
Back pain is a top primary and urgent care complaint; radicular pain can be caused by herniation of the nucleus pulposus (intervertebral disc), spinal stenosis, or degenerative changes to the vertebrae. The focus of this clinical review will be the clinical approach and treatment of lumbar radicular pain, cervical radicular pain, and spinal stenosis. Usually localized through neurological history, exam, and imaging, specific signs and symptoms for lumbar radicular, spinal stenosis, and cervical radicular pain can help determine etiology. Read More
World Neurosurg 2018 Dec 3. Epub 2018 Dec 3.
Department of Neurosurgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.
Background: Plaque characteristics play pivotal roles in ischemic events, but stenosis severity does not accurately reflect carotid plaque volume due to expansive remodeling in some patients with low-grade stenosis (LGS).
Objective: This study aimed to assess the safety, efficacy, and durability of carotid endarterectomy (CEA) for symptomatic LGS.
Methods: Study participants comprised 61 consecutive patients who underwent CEA for symptomatic carotid stenosis. Read More
Asian Spine J 2018 Dec 7. Epub 2018 Dec 7.
Department of Orthopaedics, P D Hinduja National Hospital & MRC, Mumbai, India.
Study Design: Retrospective radiological study.
Purpose: We aimed to determine the prevalence of ponticulus posticus (PP) and high-riding vertebral artery (HRVA) occurring simultaneously on the same side (PP+HRVA) and in cases of PP+HRVA, to assess C2 radio-anatomical measurements for C2 pars length, pedicle width, and laminar thickness.
Overview Of Literature: PP and HRVA predispose individuals to vertebral artery injuries during atlantoaxial fixation. Read More
Head Neck 2018 Dec 6. Epub 2018 Dec 6.
Otolaryngology Department, Hospital Clínic, Barcelona, Spain.
Background: Indications of transoral laser microsurgery (TLM) are conditioned by the risk of local relapse.
Objective: To evaluate prognostic factors of local relapse and local control with TLM (LC-TLM).
Methods: Local relapse and LC-TLM were evaluated in 1119 patients. Read More
Head Neck 2018 Dec 6. Epub 2018 Dec 6.
Division of Head and Neck Oncologic and Endocrine Surgery, Department of Otolaryngology-Head and Neck Surgery, University of California, San Francisco, San Francisco, California.
Background: This study examines the effect of insurance status (as a measure of socioeconomic status) on patient with benign thyroid disease.
Methods: A retrospective review was performed among 60 patients undergoing total thyroidectomy for benign thyroid disease. Univariate and multivariable analyses examined the relationship between insurance status and thyroid volume (sum of the left and right lobe volumes). Read More
Head Neck 2018 Dec 6. Epub 2018 Dec 6.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Background: The aim of this study was to evaluate the feasibility, safety, and early surgical outcomes of transoral thyroidectomy and to compare robotic and endoscopic procedures.
Methods: A total of 37 patients underwent robotic (23 cases) or endoscopic (14 cases) transoral thyroidectomy. We compared the outcomes of the two procedures. Read More
PLoS One 2018 6;13(12):e0208531. Epub 2018 Dec 6.
Department of Strategic Information and Research, Institute of Human Virology Nigeria, Abuja, Nigeria.
Objective: In low resource settings, visual inspection with acetic acid (VIA) by allied health workers, has been suggested as an alternative for cervical cancer screening. However, there are concerns about the objectivity and time to diagnostic concordance with specialists. We evaluated the secular trend in interobserver agreement between nurse providers and a gynecologist/colposcopist over a five-year period. Read More
J Appl Physiol (1985) 2018 Dec 6. Epub 2018 Dec 6.
Neuroscience Research Australia and The University of New South Wales, Sydney, Australia.
Briefly occluding the airway during inspiration produces a short-latency reflex inhibition in human inspiratory muscles. This occlusion reflex seems specific to respiratory muscles; however, it is not known whether the reflex inhibition has a uniform effect across a motoneurone pool when a muscle is recruited concurrently for breathing and posture. In this study, participants were seated and breathed through a mouthpiece that occluded inspiratory airflow for 250 ms at a volume threshold of 0. Read More
Biomacromolecules 2018 Dec 6. Epub 2018 Dec 6.
Delivery of clinically approved nonfluorescent drugs is facing challenges because it is difficult to monitor the intracellular drug delivery without incorporating any integrated fluorescence moiety into the drug carrier. The present investigation reports the synthesis of a pH-responsive autofluorescent polymeric nano-scaffold for the administration of nonfluorescent aromatic nitrogen mustard chlorambucil (CBL) drug into the cancer cells. Copolymerization of poly(ethylene glycol) (PEG) appended styrene and CBL conjugated N-substituted maleimide monomers enables the formation of well-defined luminescent alternating copolymer. Read More
Int Braz J Urol 2018 Oct 30;44. Epub 2018 Oct 30.
Department of Neuro-Urology, CTO - Spinal Unit, Città della Salute e della Scienza di Torino, Turin, Italy.
Purpose: The aim of our study is to evaluate the efficacy and safety of ATOMS® system for the treatment of postoperative male stress urinary incontinence (SUI).
Materials And Methods: We retrospectively evaluated all patients treated at our institution for postoperative male SUI with ATOMS® implant. We excluded patients with low bladder compliance (< 20 mL / cmH2O), uncontrolled detrusor overactivity, detrusor underactivity (BCI < 100), urethral or bladder neck stricture and low cystometric capacity (< 200 mL). Read More
Int Braz J Urol 2018 Sep 20;44. Epub 2018 Sep 20.
Department of Urology, Korea University Ansan Hospital, Korea University College of Medicine, Korea.
Introduction And Objective: Perforation of the bladder or urethra and erosion of the mesh after cystocele repair surgery are not uncommon and have potentially serious complications. Traditionally, surgical management of such complications has involved excision of the mesh using either a transurethral approach or open surgery. In this video, we present our experience of laparoscopic transvesical surgery for exposed mesh and stone. Read More
Dermatol Ther 2018 Dec 6:e12799. Epub 2018 Dec 6.
Department of Dermatology, San Jacopo Hospital, V. Ciliegiole 1, 51100 Pistoia, Italy.
Head Neck 2018 Dec 6. Epub 2018 Dec 6.
Department of Otolaryngology Head and Neck Surgery and Maxillofacial Surgery, Tel-Aviv Sourasky Medical Center, Sackler School of Medicine, Tel-Aviv University, Tel-Aviv, Israel.
Background: The prognostic value of the first posttreatment whole body integrated positron emission tomography-computed tomography (PET/CT) scanning in patients with sinonasal/skull base malignancies is undetermined.
Methods: We retrospectively reviewed the data of all patients that underwent surgery for sinonasal/skull base malignancies in 2000-2015. The results of the pretreatment and posttreatment PET/CT findings and the clinical course were retrieved. Read More
Head Neck 2018 Dec 6. Epub 2018 Dec 6.
Department of Radiation Oncology, Johann Wolfgang Goethe University, Frankfurt, Germany.
Background: For locally recurrent head and neck cancer, re-irradiation with modern techniques like stereotactic body radiotherapy is a promising, possibly curative alternative to palliative systemic therapy.
Methods: We report on 1 patient with nasopharyngeal carcinoma (NPC) and 1 patient with cutaneous squamous cell carcinoma (SCC). Both patients received full dose primary treatment (>66 Gy, EQD2), full dose re-irradiation (>50 Gy, EQD2), and a second course of re-irradiation via robotic radiosurgery (CyberKnife) for a second local recurrence. Read More
Cancer 2018 Dec 6. Epub 2018 Dec 6.
Department of Otolaryngology-Head and Neck Surgery, Johns Hopkins University School of Medicine, Baltimore, Maryland.
Background: The purpose of this study was to evaluate the influence of sex and race/ethnicity upon prevalence trends of human papillomavirus (HPV) in oropharyngeal cancer (OPC) and survival after OPC.
Method: This was a cohort study of patients included in the United States National Cancer Database who had been diagnosed with OPC between 2010 and 2015. Outcomes were HPV status of tumor specimens and overall survival. Read More
Cancer 2018 Dec 6. Epub 2018 Dec 6.
Department of Radiation Oncology, Baylor College of Medicine, Houston, Texas.
Background: Patients with head and neck cancer (HNC) experience significant physical and psychological morbidity during radiotherapy (RT) that contributes to treatment interruptions and a poor quality of life. Although spouses/partners can help by encouraging patient self-management (eg, self-care) during RT, they often experience high psychological distress rates, lack basic health care knowledge and skills, and report increased marital conflict regarding patient self-management. The current pilot study examined the feasibility and acceptability of a 6-session telephone-based intervention called Spouses coping with the Head And neck Radiation Experience (SHARE), which teaches self-management, communication, and coping skills to patients with HNC and their spouses. Read More
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
Department of Otolaryngology-Head and Neck Surgery, University of Minnesota, Minneapolis.
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
ENT Institute, Otorhinolaryngology Department, Eye and ENT Hospital of Fudan University, Shanghai, China.
Pain Med 2018 Dec 6. Epub 2018 Dec 6.
Faculty of Medicine and Health Sciences, The University of Newcastle, Newcastle, Australia.
Objectives.: To determine the extent and strength of evidence that supports the belief that cervical intervertebral discs are a source of neck pain. The evidence from anatomical, laboratory, experimental, diagnostic, and treatment studies was summarized and analyzed for concept validity, face validity, content validity, and construct validity. Read More
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
Oklahoma State University Center for Health Sciences, Tulsa.
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
Department of Psychiatry, New York State Psychiatric Institute, Vagelos College of Physicians and Surgeons, NewYork-Presbyterian/Columbia University Irving Medical Center, Columbia University, New York.
Importance: Age-related hearing loss is highly prevalent and has recently been associated with numerous morbid conditions of aging. Late-life depression is also prevalent and can be resistant to available treatments. Preliminary studies examining the association between hearing loss and late-life depression have been limited by subjective hearing measures, small sample sizes, and primarily white populations. Read More
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
Department of Otolaryngology, Far Eastern Memorial Hospital, Taipei, Taiwan.
JAMA Otolaryngol Head Neck Surg 2018 Dec 6. Epub 2018 Dec 6.
Institute for Health and Equity (Bioethics and Medical Humanities), Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin.
Appl Immunohistochem Mol Morphol 2018 Dec 4. Epub 2018 Dec 4.
Department of Clinical Specialistic and Dental Sciences.
The present study investigated the immunohistochemical expression of p53, p63, and p73 in different types of odontogenic cysts (OC), a group of common intraosseous jaw lesions, to provide a better understanding of p53-family functions in odontogenic lesions. We carried out immunohistochemical analysis to evaluate the expression of p53, p63, and p73 in 60 samples of OC, including dentigerous cysts, radicular cysts, orthokeratinized OC, and odontogenic keratocysts (OKC). The epithelial expression of p53-family members was evaluated both in the basal-parabasal and in the superficial layers, measuring the percentage of positive cells and the value of expression intensity. Read More
Am J Surg Pathol 2018 Dec 4. Epub 2018 Dec 4.
Department of Pathology, Stanford University School of Medicine, Stanford, CA.
The spectrum of tumors arising in the salivary glands is wide and has recently been shown to harbor a network of tumor-specific fusion genes. Acinic cell carcinoma (AciCC) is one of the more frequently encountered types of salivary gland carcinoma, but it has remained a genetic orphan until recently when a fusion between the HTN3 and MSANTD3 genes was described in one case. Neither of these 2 genes is known to be implicated in any other malignancy. Read More
J Pediatr Hematol Oncol 2018 Dec 4. Epub 2018 Dec 4.
Departments of Otolaryngology-Head and Neck Surgery.
This study sought to examine if modern medical evaluations including newborn screening and early diagnosis along with better methods of disease control have improved rates of hearing loss in children with sickle cell disease (SCD). Audiometric and medical data for patients with SCD was obtained from the AudGen Database and analyzed for the presence of hearing loss, type of hearing loss, severity of hearing loss, and correlation with comorbid conditions. Children with sickle cell trait (SCT) were used as a comparison group. Read More
Transbound Emerg Dis 2018 Dec 6. Epub 2018 Dec 6.
UAB, Centre de Recerca en Sanitat Animal (CReSA, IRTA-UAB), Campus de la Universitat Autònoma de Barcelona, 08193, Bellaterra, Spain.
The present study investigated the co-localization of the Middle East respiratory syndrome coronavirus (MERS-CoV) and its receptor dipeptidyl peptidase-4 (DPP4) across respiratory and lymphoid organs of experimentally MERS-CoV infected pigs and llamas by immunohistochemistry (IHC). Also, scanning electron microscopy (SEM) was performed to assess the ciliary integrity of respiratory epithelial cells in both species. In pigs, on day 2 post-inoculation (p. Read More
J Obstet Gynaecol Res 2018 Dec 6. Epub 2018 Dec 6.
Department of Obstetrics and Gynecology, Gifu Prefectural Tajimi Hospital, Tajimi, Japan.
A 41-year-old woman (gravida 2, para 1) underwent elective termination of pregnancy at approximately 7 weeks of gestation. At 1 month after the elective abortion, she was referred due to abnormal results in a cervical cytological examination. Transvaginal ultrasonography showed a heterogeneous mass of 16 mm in diameter in the left adnexal region. Read More
Saudi Med J 2018 Dec;39(12):1238-1241
Department of Otolaryngology-Head and Neck Surgery, College of Medicine, King Saud University, Riyadh, Kingdom of Saudi Arabia. E-mail.
Objectives: To determine the mean nasal skin thickness in the Middle Eastern population and to assess the effect of skin thickness on patients' satisfaction following rhinoplasty surgeries. Methods: Radiological measurements of skin thickness at the 3 vertical thirds of the nasal dorsum were taken. A total of 154 patients (80 females and 74 males) who were scheduled for computed tomography scan for the paranasal sinuses were included in the study. Read More
Public Health Nutr 2018 Dec 6:1-10. Epub 2018 Dec 6.
2Department of Nutrition and Health,Universidade Federal de Viçosa,Viçosa, MG,Brazil.
Objective: The present study aimed to investigate whether the visceral adiposity index (VAI) is an effective predictor to identify unhealthy metabolic phenotype by comparing normal-weight and overweight individuals.
Design: A population-based cross-sectional study. Data were collected by interviews, anthropometric evaluation, dietetic, clinical and laboratory tests. Read More
Med Chem 2018 Dec 5. Epub 2018 Dec 5.
Department of Chemistry, Faculty of Sciences, Atatürk University, 25240 Erzurum. Turkey.
Background: Norcantharimides are known as norcantharidine derivatives and contain an isoindole skeleton structure. Isoindole derivatives have positively effect on inflammatory pathologies including cancers.
Objective: Considering this information, firstly, isoindole derivatives containing different functional groups 4-13 have been synthesized from 2-alkyl/aryl-3a,4,7,7a-tetrahydro-1H-isoindole-1,3(2H)-dione. Read More
Scand J Surg 2018 Dec 6:1457496918816928. Epub 2018 Dec 6.
1 Heart Center, Turku University Hospital, Turku, Finland.
Background And Aims:: Cardiovascular complications are common in hip fracture patients but the role of fracture type and operative method in these is unclear. This prospective cohort study aimed to evaluate the impact of fracture- and operative characteristics on perioperative cardiovascular complications and prognosis in unselected hip fracture patients.
Material And Methods:: During a 7-month trial registration period, a population of 197 consecutive hip fracture patients (median age 84 years) diagnosed with femoral neck or pertrochanteric fracture was formed. Read More
J Biomed Opt 2018 Dec;23(12):1-4
California Institute of Technology, Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Depa, United States.
Photoacoustic endoscopy offers in vivo examination of the visceral tissue using endogenous contrast, but its typical B-scan rate is ∼10 Hz, restricted by the speed of the scanning unit and the laser pulse repetition rate. Here, we present a transvaginal fast-scanning optical-resolution photoacoustic endoscope with a 250-Hz B-scan rate over a 3-mm scanning range. Using this modality, we not only illustrated the morphological differences of vasculatures among the human ectocervix, uterine body, and sublingual mucosa but also showed the longitudinal and cross-sectional differences of cervical vasculatures in pregnant women. Read More
J Biomed Opt 2018 Dec;23(12):1-6
California Institute of Technology, Caltech Optical Imaging Laboratory, Andrew and Peggy Cherng Depa, United States.
Premature cervical remodeling is a critical precursor of spontaneous preterm birth, and the remodeling process is characterized by an increase in tissue hydration. Nevertheless, current clinical measurements of cervical remodeling are subjective and detect only late events, such as cervical effacement and dilation. Here, we present a photoacoustic endoscope that can quantify tissue hydration by measuring near-infrared cervical spectra. Read More
Pediatr Dermatol 2018 Dec 5. Epub 2018 Dec 5.
Department of Dermatology, People's Hospital of Guangxi Zhuang Autonomous Region, Nanning, China.
We evaluated the efficiency of using a 308-nm excimer laser with either tacrolimus, pimecrolimus, or halometasone for the treatment of childhood vitiligo. Patients who received combined treatments had significantly higher rates of repigmentation in comparison with individuals who underwent excimer laser alone therapy. Moreover, patients who received treatment with excimer laser and halometasone had significantly higher rates of repigmentation, even higher than individuals who were treated with tacrolimus combined or pimecrolimus combined. Read More
Clin Exp Dermatol 2018 Dec 5. Epub 2018 Dec 5.
Department of Histopathology, Postgraduate Institute of Medical Education and Research (PGIMER), Sector 12, Chandigarh, 160012, India.
J Comp Neurol 2018 Dec 6. Epub 2018 Dec 6.
Department of Physiology, Teikyo University School of Medicine, Tokyo, Japan.
The central projection patterns of cutaneous afferents from the forelimb and shoulder of mice were studied in the spinal dorsal horn after intracutaneous injection of AlexaFluor 488-conjugated and/or 594-conjugated cholera toxin subunit B (CTB). Based on their dermatomes, the following eight skin regions are thought to be innervated by spinal nerves from the sixth to eighth cervical spinal nerve roots: the dorsal surface of the shoulder, brachium, proximal forearm, distal forearm, hand, palmar surface of the second and third digits, and palm. The termination areas of afferents from the dorsal surface of the shoulder and forearm were narrow, distributed in a dorsoventral direction, and aligned in order from lateral to medial within the sixth to eighth cervical dorsal horns. Read More
Laryngoscope 2018 Dec 5. Epub 2018 Dec 5.
Department of Otorhinolaryngology-Head and Neck Surgery, University of Pennsylvania, Philadelphia, Pennsylvania.
Objectives/hypothesis: Currently, due to the rarity of pathology, there are limited data surrounding outcomes of pediatric skull base surgery. Traditionally, surgeons have proceeded with caution when electing endonasal endoscopic transsellar/transplanum approaches to the skull base in pediatric patients due to poor sphenoid pneumatization. In this study, we review outcomes of endoscopic pediatric skull base surgery based on sphenoid pneumatization patterns. Read More
J Cancer Educ 2018 Dec 5. Epub 2018 Dec 5.
University of Virginia, Charlottesville, VA, USA.
Virginia has some of the lowest HPV vaccination rates, despite being one of the few states in the USA requiring adolescent girls receive the vaccine. Provider characteristics may be an important factor in HPV vaccination. Thus, the present study assessed provider vaccination, practices, knowledge about the vaccine, and confidence in performing behaviors related to the vaccine. Read More
J Ultrasound 2018 Dec 5. Epub 2018 Dec 5.
Department of Physical Medicine and Rehabilitation, Sanggye Paik Hospital, Inje University College of Medicine, Sanggye 7 dong 761-7, Nowon-gu, 139-707, Seoul, South Korea.
Purpose: Recent studies have compared the therapeutic efficacy and safety of the procedure using ultrasound and fluoroscopy. However, there are no published studies comparing the therapeutic efficacy and safety of fluoroscopy (FL)-guided cervical interlaminar epidural steroid injection (CIESI) with that of ultrasound (US)-guided selective nerve root block (SNRB). This study aimed to compare the mid-term effects and advantages of US-guided SNRB with FL-guided CIESI for radicular pain in the lower cervical spine through assessment of pain relief and functional improvement. Read More
Forensic Sci Med Pathol 2018 Dec 5. Epub 2018 Dec 5.
Australian Marine Wildlife Research and Rescue Organization (AMWRRO), Adelaide, South Australia, 5000, Australia.
An adult male Australian sea lion (Neophoca cinerea) presented with a deep, almost circumferential, incised wound around the neck caused by a noose formed by a single strand of green nylon rope. The wound extended 4-5 cm deeply through the skin and blubber into skeletal muscle, predominantly on the dorsal surface and left side, but had not involved the airway or major vessels. The edges of the wound were sharply incised and oozing blood with a granulating infected base. Read More