6,744 results match your criteria Cerebral Venous Thrombosis


[TREATMENT DILEMMAS IN FULMINANT INTRACRANIAL HYPERTENSION].

Harefuah 2019 Feb;158(2):96-100

Department of Ophthalmology, Barzilai University Medical Center, Israel.

Introduction: Fulminant intracranial hypertension is a rare, acute presentation of idiopathic intracranial hypertension with rapid and devastating visual loss that can lead to blindness. As vision deteriorates quickly and often irreversibly, prevention of further visual loss requires emergent treatment to decrease intracranial pressure. The case presented is that of an 18 years old male with new symptoms of headaches and visual obscurations that had rapid progressive visual loss with findings of severe bilateral swollen discs. Read More

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February 2019
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Central Venous Sinus Thrombosis in a Boy With Acute Severe Ulcerative Colitis.

Front Pediatr 2019 1;7:19. Epub 2019 Feb 1.

Pediatric Gastroenterology and Nutrition Unit, Hospital Regional Universitario de Malaga, Málaga, Spain.

Cerebral venous sinus thrombosis (CVST) in childhood is uncommon. Certain diseases predispose patients to CVST, such as inflammatory bowel disease (IBD), which is considered a risk factor for developing thrombosis, which in turn is considered an extraintestinal manifestation of IBD. The use of prophylaxis in certain patients is a controversial topic. Read More

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http://dx.doi.org/10.3389/fped.2019.00019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6367252PMC
February 2019

Effect of prothrombotic genotypes on the risk of venous thromboembolism in patients with and without ischemic stroke.The TromsØ Study.

J Thromb Haemost 2019 Feb 18. Epub 2019 Feb 18.

K. G. Jebsen - Thrombosis Research and Expertise Center (TREC), Department of Clinical Medicine, UiT The Arctic University of Norway.

Background: Patients with ischemic stroke have a transient increased risk of subsequent venous thromboembolism (VTE). Prothrombotic genotypes may augment VTE risk under conditions of high thrombosis risk related to stroke.

Aims: To investigate the effect of prothrombotic genotypes in patients with ischemic stroke on the risk of VTE in a population-based case-cohort study. Read More

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http://dx.doi.org/10.1111/jth.14410DOI Listing
February 2019

An uncommon presentation of hyperhomocysteinemia and vitamin B deficiency: a case report.

J Med Case Rep 2019 Feb 18;13(1):36. Epub 2019 Feb 18.

Department of Radiodiagnosis & Imaging, Government Medical College & Hospital, Chandigarh, India.

Introduction: Cerebral venous thrombosis is relatively rare and characterized by a wide spectrum of clinical features. It is more common in young adults with women affected more than men. The diagnosis of cerebral venous thrombosis is easier nowadays due to easy access to advanced neuroimaging techniques. Read More

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http://dx.doi.org/10.1186/s13256-019-1988-9DOI Listing
February 2019

Deep Venous Thrombosis with Decreased Cerebral Blood Flow to the Thalamus was Completely Restored by Factor Xa Inhibitor.

J Stroke Cerebrovasc Dis 2019 Feb 13. Epub 2019 Feb 13.

Department of Neurosurgery, Kanazawa Medical Center, Kanazawa, Japan.

Background: Cerebral venous thrombosis is rare and an uncommon cause of stroke and has diverse etiologies and varied clinical presentations. Here, we report 2 cases of deep cerebral venous thrombosis.

Case Description: A 64-year-old woman presented with cerebral venous thrombosis due to a hypercoagulable state associated with ovarian tumor. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2019.01.023DOI Listing
February 2019

[Cerebral venous and sinus thrombosis : S2k guidelines].

Nervenarzt 2019 Feb 13. Epub 2019 Feb 13.

Institut für Public Health, Charité Universitätsmedizin, Berlin, Deutschland.

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http://dx.doi.org/10.1007/s00115-018-0654-6DOI Listing
February 2019
1 Read

Intracranial Hemorrhage with Cerebral Venous Sinus Thrombosis.

J Emerg Med 2019 Feb 9. Epub 2019 Feb 9.

Department of Emergency Medicine, Desert Regional Medical Center, Palm Springs, California.

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http://dx.doi.org/10.1016/j.jemermed.2018.12.037DOI Listing
February 2019
1 Read

Mixed cerebrovascular disease in an elderly patient with mixed vascular risk factors: a case report.

BMC Neurol 2019 Feb 12;19(1):26. Epub 2019 Feb 12.

Department of Neurology, Affiliated Hospital of Guizhou Medical University, Guiyang, Guizhou Province, China.

Background: Mixed cerebrovascular disease is a diagnostic entity that presents with hemorrhagic and ischemic stroke clinically and/or subclinically. Here, we report a patient with mixed vascular risk factors, who presented with multiple intracerebral hemorrhages and a simultaneously occurring cerebral infarction with hemorrhagic transformation.

Case Presentation: A 63-year-old male with no history of trauma or prior neurological disease presented with a sudden onset of weakness in his right limbs, followed by an episode of focal seizure without impaired awareness. Read More

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http://dx.doi.org/10.1186/s12883-019-1248-zDOI Listing
February 2019
2 Reads

Cerebral pontine infarctions during pregnancy - A case report and review of the literature.

Case Rep Womens Health 2019 Jan 23;21:e00097. Epub 2019 Jan 23.

University of South Alabama, Children's and Women's Hospital, Department of Obstetrics and Gynecology, 251 Cox Street, Mobile, AL 36604, United States.

Cerebrovascular disease is not uncommon during pregnancy as a result of either venous or arterial occlusion, or a hemorrhagic event, resulting in ischemia. Pregnancy may alter the prognosis of these neurologic disorders, with increased risks of morbidity and mortality for the mother and the developing fetus. Etiologies of stroke during pregnancy and the postpartum period include preeclampsia, eclampsia, HELLP syndrome, posterior reversible encephalopathy syndrome (PRES), amniotic fluid embolism, postpartum angiopathy, postpartum cardiomyopathy, thrombotic thrombocytopenic purpura (TTP), hemolytic uremic syndrome (HUS), cerebral venous thrombosis, CNS infections, and maternal thrombophilia. Read More

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http://dx.doi.org/10.1016/j.crwh.2019.e00097DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358547PMC
January 2019
2 Reads

Cerebral venous sinus thrombosis due to hyperhomocysteinemia with cystathionine-β-synthase (CBS) gene mutation: A case report.

Medicine (Baltimore) 2019 Feb;98(6):e14349

Department of Neurology.

Rationale: Risk factors of cerebral venous sinus thrombosis (CVST) are usually divided into acquired risks (e.g., trauma and pregnancy) and genetic risks (inherited thrombophilia). Read More

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http://dx.doi.org/10.1097/MD.0000000000014349DOI Listing
February 2019
1 Read

Neurological diseases in pregnancy.

Curr Opin Obstet Gynecol 2019 Feb 5. Epub 2019 Feb 5.

Department of Obstetrics and Gynecology, University of Rochester Medical Center, Rochester, New York, USA.

Purpose Of Review: To summarize recent research findings and current concepts related to care of neurologic diseases in pregnancy and the risks of pregnancy to the mother-infant dyad. Recent publications related to best practices for neurologic care, risks of pregnancy, rate of relapse during and after pregnancy, as well as medication safety in pregnancy and lactation for more commonly used neurologic medications are reviewed.

Recent Findings: Data continues to grow that women with neurologic conditions can experience pregnancy with minimal risks. Read More

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http://dx.doi.org/10.1097/GCO.0000000000000525DOI Listing
February 2019
1 Read

Long-term outcomes of cerebral venous sinus stenosis corrected by stenting

Curr Neurovasc Res 2019 02 6. Epub 2019 Feb 6.

Departments of Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China

Background And Purpose: Cerebral venous sinus stenosis (CVSS) usually results in severe intracranial hypertension (IH), which can be corrected by stenting immediately. However, there is a lack of evidence of the long-term good outcomes in patients with CVSS who underwent stenting.

Methods: A total of 62 patients with imaging confirmed non-thrombotic and non-external compression CVSS were enrolled into this single center real-world cohort study after undergoing stenting, and were continuously followed up for more than 12 years. Read More

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http://dx.doi.org/10.2174/1567202616666190206185133DOI Listing
February 2019
1 Read

Unilateral hearing loss in a 94-year-old patient.

Age Ageing 2019 Feb 6. Epub 2019 Feb 6.

Department of Geratology, John Radcliffe Hospital Oxford University Hospitals NHS Foundation Trust, Oxford, UK.

A case report of a 94-year-old, previously well male patient who presented with fever thought to be caused by community acquired pneumonia, new unilateral hearing loss and reduced consciousness. Despite antibiotic treatment he continued to deteriorate. Brain imaging with computer tomography and magnetic resonance imaging revealed a left otomastoiditis with osteomyelitis of the skull base, associated with an adjacent subdural empyema. Read More

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http://dx.doi.org/10.1093/ageing/afz003DOI Listing
February 2019
2 Reads

Cerebral venous thrombosis following treatment with intravenous immunoglobulin.

Med Clin (Barc) 2019 Feb 1. Epub 2019 Feb 1.

Servicio de Neurología, Hospital Universitario Miguel Servet, Zaragoza, España.

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http://dx.doi.org/10.1016/j.medcli.2018.11.002DOI Listing
February 2019
1 Read

The pathology and aetiology of subcortical clefts in infants.

Forensic Sci Int 2019 Mar 19;296:115-122. Epub 2019 Jan 19.

Department of Neuropathology and Ocular Pathology, John Radcliffe Hospital, Oxford University Hospital, Oxford, United Kingdom.

In infants, traumatic surface contusions of the brain are rare but subcortical clefts or cysts, variously labelled "contusional tears", "contusional clefts", "cortical tears" or "parenchymal lacerations" have been ascribed to trauma, and are even said to be characteristic of shaking and abuse. We describe the pathology of subcortical clefts or haemorrhages in seven infants. In none were the axonal swellings characteristic of traumatic axonal injury seen in relation to the clefts. Read More

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http://dx.doi.org/10.1016/j.forsciint.2019.01.011DOI Listing
March 2019
2 Reads

[Risk factors for recurrent thrombosis in patients with polycythemia vera and essential thrombocythemia].

Zhonghua Xue Ye Xue Za Zhi 2019 Jan;40(1):17-23

Department of Hematology, Beijing Anzhen Hospital, Capital Medical University, Beijing 100029, China.

To analyze the clinical characteristics of recurrent thrombosis in patients with polycythemia vera (PV) and essential thrombocythemia (ET) to probe the risk factors for recurrent thrombosis in patients with ET and PV. The clinical data of 104 ET and PV patients with thrombosis in Beijing Anzhen Hospital from February 2001 to November 2016 were retrospectively analyzed. Thrombosis reoccurred in 38 patients. Read More

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http://dx.doi.org/10.3760/cma.j.issn.0253-2727.2019.01.004DOI Listing
January 2019
2 Reads

Headache and inflammatory bowel disease: think cerebral vein!

BMJ Case Rep 2019 Jan 29;12(1). Epub 2019 Jan 29.

Paediatric Gastroenterology, Hepatology and Nutrition, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Cerebral vein thrombosis is a severe complication of inflammatory bowel disease, can cause non-specific symptoms and hence lead to delay in diagnosis. We report the case of an adolescent with inflammatory bowel disease who developed extensive cerebral vein thrombosis requiring a ventriculoperitoneal shunt. Diagnosis was markedly delayed due to repeated misinterpretation of clinical signs and laboratory findings and the lack of reconsidering the working diagnosis despite the involvement of several medical subspecialties. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22722
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http://dx.doi.org/10.1136/bcr-2018-227228DOI Listing
January 2019
3 Reads

Cerebral venous thrombosis as an initial manifestation of acute myeloid leukemia.

Oxf Med Case Reports 2019 Jan 24;2019(1):omy118. Epub 2019 Jan 24.

Haematology Unit, Department of Internal Medicine, Sarawak General Hospital, Sarawak, Malaysia.

Cancer-associated thromboembolism is not an uncommon complication in patients with malignancies. No study has reported the occurrence of thromboembolism prior to the diagnosis of acute myeloid leukemia (AML). Most reports are anectodal and data are scarce on this subject. Read More

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http://dx.doi.org/10.1093/omcr/omy118DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6345084PMC
January 2019

Cerebrovascular manifestations of herpes simplex virus infection of the central nervous system: a systematic review.

J Neuroinflammation 2019 Jan 29;16(1):19. Epub 2019 Jan 29.

Department of Neurology, Christian Doppler Medical Center, Paracelsus Medical University, Ignaz-Harrer-Str. 79, 5020, Salzburg, Austria.

Background: Intracerebral hemorrhage and ischemic stroke are increasingly recognized complications of central nervous system (CNS) infection by herpes simplex virus (HSV).

Aim Of The Study: To analyze clinical, imaging, and laboratory findings and outcomes of cerebrovascular manifestations of HSV infection.

Methods: Systematic literature review from January 2000 to July 2018. Read More

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http://dx.doi.org/10.1186/s12974-019-1409-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6352343PMC
January 2019
1 Read

Vein of Labbe thrombosis, a near-miss.

Brain Circ 2018 Oct-Dec;4(4):188-190. Epub 2018 Dec 31.

Department of Neurology, Yale School of Medicine, New Haven, CT, USA.

Emergency department visits for a headache are relatively common, and in most cases, the etiologies of the headache are typically benign. We present a case of a patient who presented to the emergency room for new onset of unremitting unilateral headache. She subsequently had two hospital visits and three separate imaging modalities to identify vein of Labbe thrombosis. Read More

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http://dx.doi.org/10.4103/bc.bc_34_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6329210PMC
December 2018
1 Read

Bleeding and Thromboembolism After Traumatic Brain Injury in the Elderly: A Real Conundrum.

J Surg Res 2019 Mar 6;235:615-620. Epub 2018 Dec 6.

Department of Epidemiology and Public Health, University of Maryland School of Medicine, Baltimore, Maryland.

Background: Elderly patients presenting with a traumatic brain injury (TBI) often have comorbidities that increase risk of thromboembolic (TE) disease and recurrent TBI. A significant number are on anticoagulant therapy at the time of injury and studies suggest that continuing anticoagulation can prevent TE events. Understanding bleeding, recurrent TBI, and TE risk after TBI can help to guide therapy. Read More

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http://dx.doi.org/10.1016/j.jss.2018.10.021DOI Listing

[Cardiac papillary fibroelastoma and stroke during pregnancy: Case report].

Ann Cardiol Angeiol (Paris) 2019 Jan 24. Epub 2019 Jan 24.

UFR de médecine Paris VII, service de cardiologie, CHU de Bichat Claude-Bernard, Denis-Diderot, 46, rue Henri-Huchard, 75877 Paris, France.

Stroke occurring during pregnancy is linked to high mortality. Stroke may be directly related to pregnancy (e.g. Read More

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http://dx.doi.org/10.1016/j.ancard.2018.10.010DOI Listing
January 2019
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Management of Stroke in Neonates and Children: A Scientific Statement From the American Heart Association/American Stroke Association.

Stroke 2019 Jan 28:STR0000000000000183. Epub 2019 Jan 28.

Purpose- Much has transpired since the last scientific statement on pediatric stroke was published 10 years ago. Although stroke has long been recognized as an adult health problem causing substantial morbidity and mortality, it is also an important cause of acquired brain injury in young patients, occurring most commonly in the neonate and throughout childhood. This scientific statement represents a synthesis of data and a consensus of the leading experts in childhood cardiovascular disease and stroke. Read More

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http://dx.doi.org/10.1161/STR.0000000000000183DOI Listing
January 2019

Incidence of Dural Venous Sinus Thrombosis in Patients with Glioblastoma and Its Implications.

World Neurosurg 2019 Jan 24. Epub 2019 Jan 24.

Faculty of Medicine, University of Toronto, Toronto, Ontario, Canada. Electronic address:

Objective: Glioblastoma (GBM) is associated with increased risk of developing dural venous sinus thrombosis (DVST), which often goes undiagnosed as symptoms are readily attributed to tumor. The purpose of this study was to investigate the incidence of DVST, potential predictive features on imaging, complications, its effect on survival, and time of greatest risk for developing DVST.

Methods: A retrospective search of patients with GBM who had surgery followed by chemotherapy and/or radiation therapy between 2009 and 2015 at our institution was performed. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.039DOI Listing
January 2019
1 Read

Batroxobin in combination with anticoagulation may promote venous sinus recanalization in cerebral venous thrombosis: A real-world experience.

CNS Neurosci Ther 2019 Jan 23. Epub 2019 Jan 23.

Departments of Neurology and Neurosurgery, Xuanwu Hospital, Capital Medical University, Beijing, China.

Aims: The objective of this study was to evaluate cerebral venous recanalization with magnetic resonance black-blood thrombus imaging (MRBTI) in patients with cerebral venous thrombosis (CVT) who underwent batroxobin treatment in combination with anticoagulation.

Methods: A total of 31 CVT patients were enrolled in this real-world registry study. The patients were divided into batroxobin (n = 21) and control groups (n = 10). Read More

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http://dx.doi.org/10.1111/cns.13093DOI Listing
January 2019
1 Read

Diagnosis and Management of Cerebral Venous Diseases in Neuro-Ophthalmology: Ongoing Controversies.

Asia Pac J Ophthalmol (Phila) 2019 Jan 23. Epub 2019 Jan 23.

Department of Ophthalmology, Weill Cornell Medical College, New York, United States.

Diseases of the cerebral venous system frequently lead to neuro-ophthalmic complications. Cortical venous sinus thrombosis and dural arteriovenous fistulas may be complicated by elevation of intracranial pressure, with secondary papilledema or abducens palsies. There is increasing recognition that stenosis at the transverse sinus-sigmoid sinus junction plays a role in the pathophysiology of idiopathic intracranial hypertension and offers a new avenue of treatment in patients who fail medical therapy. Read More

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http://dx.doi.org/10.22608/APO.2018239DOI Listing
January 2019
3 Reads

[Headache and stroke].

MMW Fortschr Med 2019 Jan;161(1):62-66

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http://dx.doi.org/10.1007/s15006-019-0071-1DOI Listing
January 2019

Acute otitis media associated with Gradenigo syndrome and transverse sinus thrombosis: a case report.

J Int Med Res 2019 Jan 22:300060518823404. Epub 2019 Jan 22.

Kırşehir Ahi Evran University, Kırşehir, Turkey.

Gradenigo syndrome is associated with middle ear infection that extends to the petrous apex, leading to pain at the innervation site of the ophthalmic and maxillary branches of the trigeminal nerve and the development of abducens nerve palsy. Cerebral venous sinus thrombosis is a serious neurological complication of otitis media and occurs secondary to spread of the infection to the underlying bone. We herein report a pediatric case of otitis media associated with Gradenigo syndrome and ipsilateral sigmoid-transverse sinus thrombosis with magnetic resonance imaging findings. Read More

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http://dx.doi.org/10.1177/0300060518823404DOI Listing
January 2019
2 Reads

Mechanical Thrombectomy with Intraoperative Local Thrombolysis Versus Mechanical Thrombectomy with Continuous Thrombolysis for Treatment of Cerebral Venous Sinus Thrombosis: A Systematic Review of 82 Cases.

World Neurosurg 2019 Jan 17. Epub 2019 Jan 17.

Department of Neurosurgery, Chinese Medicine Hospital of Zhejiang Province, The First Affiliated Hospital of Zhejiang Chinese Medicine University, Zhejiang Chinese Medicine University, Hangzhou, Zhejiang, China.

Objective: The first-line treatment of cerebral venous sinus thrombosis (CVST) is systemic anticoagulation. However, patients with severe or a clinically worsening condition might benefit from mechanical thrombectomy (MT) combined with intraoperative thrombolysis (IOT) or MT with continuous thrombolytic infusion (CTI). The present study compared the efficacy and safety of these 2 endovascular therapeutic methods by performing a systematic review of the literature. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.193DOI Listing
January 2019
1 Read

Diagnostic accuracy of noncontrast CT imaging markers in cerebral venous thrombosis.

Neurology 2019 Feb 18;92(8):e841-e851. Epub 2019 Jan 18.

From the Departments of Radiology (P.-J.B., P.D.) and Neurology (R.L.), University Hospitals Leuven, Belgium; Department of Neurology (S.M.Z., J.M.C.), Amsterdam University Medical Centers, Amsterdam, the Netherlands; Department of Neurology (C.-G.E.), John Hunter Hospital, University of Newcastle, Australia; Stroke Department (M.A.B., A.A.), Instituto Nacional de Neurología y Neurocirugía Dr. Manuel Velasco Suárez, México City, México; Department of Head and Neck (P.C.), Neurology Unit, Fondazione Poliambulanza, Brescia, Italy; Departments of Head and Neck (P.C.) and Clinical and Experimental Sciences (A.P.), Neurology Clinic, University of Brescia, Italy; Neurology Department (I.E., J.M.), University Hospitals Virgen del Rocio and Macarena, Seville; Neurovascular Lab (I.E., J.M.), Instituto de Biomedicina de Sevilla, Spain; Department of Neurology (D.R.), Nîmes University Hospital, France; Department of Neurosciences (R.L.), Experimental Neurology and Leuven Institute for Neuroscience and Disease (LIND), KU Leuven-University of Leuven; Laboratory of Neurobiology (R.L.), Center for Brain & Disease Research, VIB, Leuven, Belgium; Departments of Radiology (N.H.) and Neurology (F.F., T.G.), Medical University of Graz, Austria; Department of Neurology (J.J.C., E.G.-S.), Neurovascular Research Group, IMIM-Hospital del Mar, Barcelona; Universitat Autònoma de Barcelona (J.J.C., E.G.-S.), Spain; Department of Neurology (S.H., J.P., T.T.), Helsinki University Hospital, Finland; Department of Neurology (J.M.), Hospital Universitario Virgen Macarena, Seville, Spain; Department of Neurology (C.W.), University Hospital Essen, Germany; The Florey Institute of Neuroscience and Mental Health (L.C.), University of Melbourne; Australia School of Medicine (H.A.), Faculty of Health, Deakin University; Interventional Neuroradiology Service (H.A.), Radiology Department, Austin Health, Melbourne; Interventional Neuroradiology Service (H.A.), Radiology Department, Monash Health, Melbourne, Australia; Department of Clinical Neuroscience/Neurology (T.T.), Institute of Neuroscience and Physiology, Sahlgrenska Academy at University of Gothenburg; Department of Neurology (T.T.), Sahlgrenska University Hospital, Gothenburg, Sweden; Stroke Division, Florey Institute of Neuroscience and Mental Health (V.T.), University of Melbourne, Heidelberg; and Department of Neurology (V.T.), Austin Health, Heidelberg, Australia.

Objective: To assess the added diagnostic value of semiquantitative imaging markers on noncontrast CT scans in cerebral venous thrombosis (CVT).

Methods: In a retrospective, multicenter, blinded, case-control study of patients with recent onset (<2 weeks) CVT, 3 readers assessed (1) the accuracy of the visual impression of CVT based on a combination of direct and indirect signs, (2) the accuracy of attenuation values of the venous sinuses in Hounsfield units (with adjustment for hematocrit levels), and (3) the accuracy of attenuation ratios of affected vs unaffected sinuses in comparison with reference standard MRI or CT angiography. Controls were age-matched patients with (sub)acute neurologic presentations. Read More

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http://dx.doi.org/10.1212/WNL.0000000000006959DOI Listing
February 2019
1 Read
8.286 Impact Factor

Paediatric presentation of intracranial haemorrhage due to thrombosis of a developmental venous anomaly.

BMJ Case Rep 2019 Jan 17;12(1). Epub 2019 Jan 17.

Neurosurgery, Albany Medical Center, Albany, New York, USA.

Developmental venous anomalies (DVAs) are the most commonly encountered cerebral malformations. While generally asymptomatic and discovered as incidental findings, there is a small number that can cause intracranial haemorrhage, usually attributed to associated cavernomas; however, venous thrombosis of the draining vein is a rare cause. A 10-year-old woman presented with seizure episodes. Read More

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http://dx.doi.org/10.1136/bcr-2018-227362DOI Listing
January 2019
2 Reads

Rare presentation of iron deficiency anaemia with cerebral venous sinus thrombosis in a middle-aged woman.

BMJ Case Rep 2019 Jan 17;12(1). Epub 2019 Jan 17.

Department of General Medicine, East Sussex Healthcare NHS Trust, Saint Leonards-on-Sea, UK.

This is a case of a female patient presented with a mild headache associated with recurrent episodes of nausea and vomiting, confusion and right-sided hemiparesis, diagnosed of haemorrhagic venous infarction from the thrombosis of left transverse and sigmoid sinus and probably the left vein of Labbe. She had severe microcytic hypochromic anaemia due to iron deficiency, without any other risk factors for cerebral venous thrombosis such as trauma history, infections, coagulation disorders or autoimmune diseases. She had a good prognosis after iron supplementation and anticoagulation therapy. Read More

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http://casereports.bmj.com/lookup/doi/10.1136/bcr-2018-22585
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http://dx.doi.org/10.1136/bcr-2018-225851DOI Listing
January 2019
6 Reads

Dietary intake of marine n-3 polyunsaturated fatty acids and future risk of venous thromboembolism.

Res Pract Thromb Haemost 2019 Jan 13;3(1):59-69. Epub 2018 Dec 13.

K.G Jebsen Thrombosis Research and Expertise Center (TREC) Department of Clinical Medicine UiT-The Arctic University of Norway Tromsø Norway.

Background: Studies on the association between long-chained n-3 polyunsaturated fatty acids (n-3 PUFAs) and risk of venous thromboembolism (VTE) are conflicting, potentially due to challenges related to assessment of n-3 PUFA intake and changes in diet during follow-up.

Objectives: To investigate whether dietary intake of marine n-3 PUFAs was associated with risk of incident VTE in a population-based cohort with repeated assessments of n-3 PUFA intake.

Methods: We recruited 21 970 participants (after excluding 7570 with incomplete data) from the fourth (1994-1995) and sixth (2007-2008) surveys of the Tromsø Study, and recorded incident VTEs up to 2016. Read More

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http://dx.doi.org/10.1002/rth2.12168DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6332709PMC
January 2019
1 Read

Cerebral sinovenous thrombosis as a complication of otitis media.

Clin Case Rep 2019 Jan 4;7(1):186-188. Epub 2018 Dec 4.

Pediatric resident PGY-2 Dayton Children's Hospital Dayton Ohio.

Otogenic cerebral sinovenous thrombosis (CSVT) is a rare complication of otitis media and associated with significant morbidity and mortality. Classic clinical signs of mastoiditis (pain, swelling, and erythema posterior to the pinna) are not always present at presentation. Treatment of otogenic CSVT consists of conservative surgery, antibiotics, and anticoagulation. Read More

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http://dx.doi.org/10.1002/ccr3.1948DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6333077PMC
January 2019
1 Read

Percutaneous transforaminal endoscopic discectomy in the treatment of senior patients with lumbar degenerative disc disease.

Exp Ther Med 2019 Jan 20;17(1):874-882. Epub 2018 Nov 20.

Department of Spinal Surgery, The Third Hospital of Hebei Medical University, Key Biomechanical Laboratory of Orthopedics, Shijiazhuang, Hebei 050051, P.R. China.

The aim of the current study was to analyze the efficacy of percutaneous transforaminal endoscopic discectomy (PTED) in the treatment of lumbar degenerative disc disease for senior patients. The clinical and follow-up data of senior patients were retrospectively reviewed. Patients were divided into a PTED group and an open surgery group. Read More

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http://www.spandidos-publications.com/10.3892/etm.2018.6996
Publisher Site
http://dx.doi.org/10.3892/etm.2018.6996DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307357PMC
January 2019
5 Reads

Near-complete recanalization of jugular vein and multiple dural sinus thromboses with warfarin in a case of antiphospholipid syndrome.

Reumatologia 2018 23;56(6):406-408. Epub 2018 Dec 23.

Department of Rheumatology, Trakya University School of Medicine, Edirne, Turkey.

Antiphospholipid syndrome is a cause of arterial and venous thrombosis especially in the young adult population. Although dural sinus thrombosis is a relatively rare complication of antiphospholipid syndrome, it may be a cause of morbidity and mortality. Extension of thrombosis and involvement of deep venous structures are poor prognostic factors in patients with dural sinus thrombosis, but the rate of near-complete recanalization is not known in antiphospholipid syndrome-related dural sinus thrombosis. Read More

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http://dx.doi.org/10.5114/reum.2018.80720DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330675PMC
December 2018
1 Read

An Early Pregnant Chinese Woman with Cerebral Venous Sinus Thrombosis Succeeding in Induction of Labor in the Second Trimester.

Chin Med Sci J 2018 12;33(4):267-271

Department of Radiology, Beijing Chaoyang Hospital, Capital Medical University, Beijing 100020, China.

Cerebral venous sinus thrombosis (CVST) is a rare condition in early pregnancy. A 22-year-old Chinese woman at 10 weeks of pregnancy requested induced abortion and was diagnosed as CVST for a severe headache accompanying with nausea and vomiting. The patient was treated successfully with anticoagulation, followed by amniocentesis, and finally succeeded in induction of labor safely. Read More

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http://dx.doi.org/10.24920/31806DOI Listing
December 2018
2 Reads

[Etiologies and risk factors for young people with intracerebral hemorrhage].

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2018 Nov;43(11):1246-1250

Department of Geriatrics Neurology, Xiangya Hospital, Central South University, Changsha 410008, China.

Objective: To determine the etiologies and risk factors of intracerebral hemorrhage in young people.
 Methods: A total of 401 young patients with intracerebral hemorrhage were enrolled, and they were assigned into a 20-29 , a 30-39, and a 40-45 age group. The differences of various etiologies and risk factors among the three groups were analyzed. Read More

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http://www.csumed.org/xbwk/CN/10.11817/j.issn.1672-7347.2018
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http://dx.doi.org/10.11817/j.issn.1672-7347.2018.11.013DOI Listing
November 2018
5 Reads

Does a change in ventricular size predict a diagnosis of cerebral venous thrombosis-related acute intracranial hypertension? Results of a retrospective imaging study.

Acta Radiol 2019 Jan 12:284185118823346. Epub 2019 Jan 12.

4 Department of Radiology, The Affiliated Hospital of Qingdao University, Qingdao, PR China.

Background: Acute intracranial hypertension (IH) is commonly found in patients with cerebral venous thrombosis (CVT). Some magnetic resonance imaging (MRI) findings that are suggestive of acute IH and are thus important for planning treatment and improving clinical outcomes have been reported; however, the significance of changes in ventricular size in the presence of acute CVT-related IH remains unclear.

Purpose: To investigate changes in ventricular size in patients with CVT-related IH by MRI and to determine whether such changes are predictors of IH in these patients. Read More

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http://dx.doi.org/10.1177/0284185118823346DOI Listing
January 2019
3 Reads

Hypertrophic pachymeningitis and cerebral venous thrombosis in myeloperoxidase-ANCA associated vasculitis.

BMJ Case Rep 2019 Jan 10;12(1). Epub 2019 Jan 10.

Department of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University, Chieti, Italy.

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http://dx.doi.org/10.1136/bcr-2018-226780DOI Listing
January 2019
2 Reads

Endovascular Treatment of Cerebral Venous Sinus Thrombosis and Insights into Intracranial Coagulopathy.

J Stroke Cerebrovasc Dis 2019 Jan 8. Epub 2019 Jan 8.

Columbia University, Vagelos College of Physicians & Surgeons, New York, New York.

Cerebral venous sinus thrombosis (CVST) requires anticoagulation to promote vessel recanalization. Current anticoagulation paradigms utilize plasma tests from peripheral venous/arterial samples for therapeutic monitoring. We describe a medically-refractory case of CVST in a 35-year-old woman later found to have JAK2 mutation and essential thrombocytosis. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S10523057183071
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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.12.015DOI Listing
January 2019
9 Reads

Cerebral Venous Sinus Thrombosis in Systemic Lupus Erythematosus.

Acta Med Indones 2018 Oct;50(4):343-345

Department of Internal Medicine, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia.

A 38-year-old woman presented with general weakness and vaginal bleeding. One month prior, she had been diagnosed with Evans syndrome (haemolytic anemia with positive Coombs test and thrombocytopenia) and was given oral steroid as maintenance therapy. Her serology examination was negative for hepatitis B, hepatitis C, and human immunodeficiency virus (HIV). Read More

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October 2018
9 Reads

Stroke due to Paradoxical Embolization Related to Fibroid Uterus Enlargement Compressing the Right Common Iliac Vein.

Case Rep Neurol 2018 Sep-Dec;10(3):328-331. Epub 2018 Nov 23.

Department of Neurology, Loyola University Chicago Stritch School of Medicine, Maywood, Illinois, USA.

Stroke in young women is commonly cryptogenic or associated with an underlying hypercoagulable state (e.g., hormonal contraception). Read More

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http://dx.doi.org/10.1159/000494126DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323390PMC
November 2018
3 Reads

A Child with Tuberculous Meningitis Complicated by Cortical Venous and Cerebral Sino-Venous Thrombosis.

Indian J Pediatr 2019 Jan 9. Epub 2019 Jan 9.

Department of Pediatrics, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, 160012, India.

Stroke is common in tuberculous meningitis. Stroke commonly affects the tubercular zone, comprising the anterior part of the thalamus, caudate and the internal capsule (anterior limb and genu). Stroke, in tuberculous meningitis is predominantly arterial ischemic stroke, and is due to infiltrative, proliferative or necrotizing arteritis. Read More

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http://link.springer.com/10.1007/s12098-018-2830-x
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http://dx.doi.org/10.1007/s12098-018-2830-xDOI Listing
January 2019
7 Reads
0.919 Impact Factor

Postpartum Period Is a Risk Factor for Cerebral Venous Thrombosis.

Stroke 2019 Feb;50(2):501-503

From the Department of Neurology (S.M.S., S.M.Z., J.M.C.), Academic Medical Center, Amsterdam, the Netherlands.

Background and Purpose- Pregnancy and the postpartum period are generally considered to be risk factors for cerebral venous thrombosis (CVT), but no controlled studies have quantified the risk. Methods- Case-control study using data of consecutive adult patients with CVT from 5 academic hospitals and controls from the Dutch MEGA study (Multiple Environmental and Genetic Assessment of risk factors for venous thrombosis). Men, women over the age of 50, women using oral contraceptives or with a recent abortion or miscarriage were excluded. Read More

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https://www.ahajournals.org/doi/10.1161/STROKEAHA.118.023017
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http://dx.doi.org/10.1161/STROKEAHA.118.023017DOI Listing
February 2019
9 Reads

A phase 1, first-in-human study of F-GP1 positron emission tomography for imaging acute arterial thrombosis.

EJNMMI Res 2019 Jan 7;9(1). Epub 2019 Jan 7.

Department of Nuclear Medicine, Asan Medical Center, University of Ulsan College of Medicine, 88, Olympic-ro 43-gil, Songpa-gu, Seoul, 05505, Republic of Korea.

Background: F-GP1 is a novel positron emission tomography (PET) tracer that targets glycoprotein IIb/IIIa receptors on activated platelets. The study objective was to explore the feasibility of directly imaging acute arterial thrombosis (AAT) with F-GP1 PET/computed tomography (PET/CT) and to quantitatively assess F-GP1 uptake. Safety, biodistribution, pharmacokinetics and metabolism were also evaluated. Read More

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http://dx.doi.org/10.1186/s13550-018-0471-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6323046PMC
January 2019
1 Read

Venous thromboembolic events in patients undergoing craniotomy for tumor resection: incidence, predictors, and review of literature.

J Neurosurg 2019 Jan 4:1-12. Epub 2019 Jan 4.

1Department of Neurological Surgery, Mayo Clinic.

OBJECTIVEThe authors sought to investigate the incidence and predictors of venous thromboembolic events (VTEs) after craniotomy for tumor resection, which are not well established, and the efficacy of and risks associated with VTE chemoprophylaxis, which remains controversial.METHODSThe authors investigated the incidence of VTEs in a consecutive series of patients presenting to the authors' institution for resection of an intracranial lesion between 2012 and 2017. Information on patient and tumor characteristics was collected and independent predictors of VTEs were determined using stepwise multivariate logistic regression analysis. Read More

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http://dx.doi.org/10.3171/2018.7.JNS181175DOI Listing
January 2019
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Cerebral Venous Thrombosis with Tumor-like Features: A Case Report and Review of the Literature.

World Neurosurg 2019 Jan 2. Epub 2019 Jan 2.

Department of Neurosurgery, Fujian Medical University Union Hospital, Fuzhou, Fujian Province, China. Electronic address:

Background: Cerebral venous thrombosis (CVT), a rare cerebrovascular condition, is induced by blocked cerebral venous reflux, often presenting non-specific symptoms. Magnetic resonance imaging (MRI) of the brain may improve the often elusive diagnosis of CVT. However, the sensitivity, specificity and full spectrum of such MRI findings are poorly understood. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.12.109DOI Listing
January 2019

Optimization of 3D phase contrast venography for the assessment of the cranio-cervical venous system at 1.5 T.

Neuroradiology 2019 Jan 4. Epub 2019 Jan 4.

Section Biomedical Imaging, Molecular Imaging North Competence Center (MOIN CC), Department for Radiology and Neuroradiology, University Medical Center, Arnold Heller Street 3, Building 41, 24105, Kiel, Germany.

Purpose: The aim of this work was to optimize a three-dimensional (3D) phase-contrast venography (PCV) product MR pulse sequence in order to obtain clinically reliable images with less artifacts for an improved depiction of the cranio-cervical venous vessels.

Methods: Starting from the product sequence, the 3D PCV protocol was optimized in eight steps with respect to the velocity encoding (V) direction and value, slice thickness, reduction of susceptibility artifacts and arterial contamination, gradient mode and radio-frequency (RF)-spoiling, B-Shimming, asymmetric echo technique and RF-pulse type, and flip angle. The product and optimized protocol was used to perform 3D PCV in 12 healthy male volunteers with a median age of 50 years using a state-of-the-art 1. Read More

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http://dx.doi.org/10.1007/s00234-018-2146-6DOI Listing
January 2019
2 Reads

Spectrum of Cerebral Venous Thrombosis in Oman.

Sultan Qaboos Univ Med J 2018 Aug 19;18(3):e329-e337. Epub 2018 Dec 19.

Department of Medicine, Sultan Qaboos University Hospital, Sultan Qaboos University, Muscat, Oman.

Objectives: Cerebral venous thrombosis (CVT) can have varied and life-threatening manifestations. This study aimed to examine the spectrum of its clinical presentations and outcomes in a tertiary hospital in Oman.

Methods: This retrospective study was conducted at the Sultan Qaboos University Hospital, Muscat, Oman, between January 2009 and December 2017. Read More

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http://dx.doi.org/10.18295/squmj.2018.18.03.011DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6307648PMC
August 2018
1 Read