7,288 results match your criteria Cerebral Venous Thrombosis


Endovascular treatment for cerebral venous sinus thrombosis - a single center study.

Br J Neurosurg 2020 Jul 10:1-7. Epub 2020 Jul 10.

Department of Radiology, Neurovascular Section, Copenhagen University Hospital, Rigshospitalet, Denmark.

Background: Cerebral venous sinus thrombosis (CVST) is a rare cerebrovascular disorder. The majority of these patients respond favorably to systemic anticoagulation. However, a subset of patients will deteriorate clinically, despite optimal medical therapy. Read More

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http://dx.doi.org/10.1080/02688697.2020.1786498DOI Listing

Cerebral venous thrombosis and submandibular lithotripsy: A case report.

Rev Neurol (Paris) 2020 Jul 6. Epub 2020 Jul 6.

Department of neurology, Compiègne Hospital, France.

We present the case of a 38-year-old woman with a diagnosis of cerebral venous thrombosis that developed after lithotripsy of the submandibular gland. Few cases of vessel thrombosis after lithotripsy have been reported in other organs, this is the unique cerebral case reported. Read More

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http://dx.doi.org/10.1016/j.neurol.2020.04.019DOI Listing

Meningoradiculitis due to varicella zoster virus reactivation in a patient treated with ixekizumab.

Ann Dermatol Venereol 2020 Jun 30. Epub 2020 Jun 30.

Dermatology department, Jean-Bernard hospital, Valenciennes, France.

Introduction: Ixekizumab is a recently developed biopharmaceutical used since 2016 in the US and Europe for the treatment of plaque psoriasis. Few adverse effects have been reported in the literature and ixekizumab is not known to increase the risk of viral reactivation. Herein we report the case of an immunocompetent female patient treated with ixekizumab who presented meningoradiculitis due to varicella zoster virus (VZV) reactivation. Read More

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http://dx.doi.org/10.1016/j.annder.2020.04.020DOI Listing

Potential underlying mechanisms of cerebral venous thrombosis associated with COVID-19.

J Neuroradiol 2020 Jun 26. Epub 2020 Jun 26.

Department of Diagnostic Sciences, Ghent University, Ghent, Belgium.

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http://dx.doi.org/10.1016/j.neurad.2020.06.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7319640PMC

Dural Venous Sinus Thrombosis in Patients Presenting with Blunt Traumatic Brain Injuries and Skull Fractures: A Systematic Review and Meta-analysis.

World Neurosurg 2020 Jun 29. Epub 2020 Jun 29.

Department of Surgery, Division of Neurosurgery, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.

Introduction: Dural venous sinus thrombosis (DVST) is an increasingly recognized complication of blunt traumatic brain injury (TBI) and skull fractures. However, data concerning the epidemiology and clinical significance of this entity is unclear. Determining the disease burden in the TBI population is an important first step to guide future studies assessing the natural course of traumatic DVST or the effects of its treatment. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.117DOI Listing

Squamous cell carcinoma of the scalp causing cortical venous thrombosis and Intraparenchymal hematoma.

eNeurologicalSci 2020 Sep 18;20:100251. Epub 2020 Jun 18.

Department of Neurosurgery, University of California San Diego. La Jolla, CA, USA.

•We present a case of squamous cell carcinoma causing cortical venous thrombosis (CoVT)•This is the first case of an invasive scalp lesion causing CoVT and brain hemorrhage•Some cases of CoVT may be managed conservatively•Recurrent, invasive squamous cell carcinoma remains therapeutically challenging. Read More

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http://dx.doi.org/10.1016/j.ensci.2020.100251DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7317240PMC
September 2020

Reversible Splenial Lesion Syndrome with Some Novel Causes and Clinical Manifestations.

Intern Med 2020 Jun 30. Epub 2020 Jun 30.

Department of Neurology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, China.

Objective Reversible Splenial Lesion Syndrome (RESLES) is a clinical radiological syndrome characterized by a reversible lesion of the splenium of the corpus callosum with a decreased apparent diffusion coefficient (ADC) value. The clinical manifestations of RESLES are diverse. Methods Fifteen cases of adult RESLES patients (10 males and 5 females) were retrospectively selected from the radiology system using the key word "corpus callosum" at a university-affiliated tertiary care hospital between May 1, 2015 and Dec 31, 2019. Read More

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http://dx.doi.org/10.2169/internalmedicine.4516-20DOI Listing

Brain CT Findings in Patients with First-Onset Seizure Visiting the Emergency Department in Mashhad, Iran.

Open Access Emerg Med 2020 10;12:159-162. Epub 2020 Jun 10.

Department of Neurosurgery, Faculty of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.

Introduction: Regarding the complications and costs of CT imaging for patients, this study aimed at investigating the necessity of CT scans in patients visiting the emergency unit with first-onset seizure.

Methods: One hundred patients who had experienced their first seizure were enrolled. Their CT scan was studied, and based on the radiology report, the type of probable pathologies and their percentage were determined. Read More

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http://dx.doi.org/10.2147/OAEM.S241124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7293958PMC

COVID-19 and Stroke: Incidental, Triggered or Causative.

Ann Indian Acad Neurol 2020 May-Jun;23(3):318-324. Epub 2020 Jun 10.

Department of Neurology, All India Institute of Medical Sciences, New Delhi, India.

Stroke is a serious neurological comorbidity observed during the ongoing COVID-19 (coronavirus associated disease 2019) pandemic caused by SARS-CoV-2 (severe acute respiratory syndrome, corona virus 2) and includes ischemic stroke, intracerebral haemorrhage and cerebral venous thrombosis. We reviewed factors that could potentially contribute to the occurrence of stroke among patients with COVID-19. There could be an interaction between the conventional risk factors of stroke, infection, systemic inflammatory response and plaque destabilisation. Read More

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http://dx.doi.org/10.4103/aian.AIAN_380_20DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7313589PMC

Children With Behçet Disease-associated Thrombosis: A Single-Center Experience.

J Pediatr Hematol Oncol 2020 Jun 26. Epub 2020 Jun 26.

Department of Pediatric Hematology and Oncology, Ankara City Hospital, Yildirim Beyazit University, Ankara, Turkey.

Behçet disease (BD) is a systemic vasculitis that can be complicated with thrombosis, which is an important cause of mortality and morbidity. The course of BD is more severe, and the diagnosis is usually delayed. In children, thrombosis associated with BD is very rare. Read More

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http://dx.doi.org/10.1097/MPH.0000000000001877DOI Listing

COVID-19 as triggering co-factor for cortical cerebral venous thrombosis?

J Neuroradiol 2020 Jun 27. Epub 2020 Jun 27.

ESO Stroke Unit, Europe Hospitals, avenue de Fré 206, 1180 Brussels, Belgium. Electronic address:

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http://dx.doi.org/10.1016/j.neurad.2020.06.008DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7320695PMC

Cerebral venous thrombosis associated with coronavirus infection: an underestimated entity?

Neurol Sci 2020 Jun 29. Epub 2020 Jun 29.

Neurological Department, "Alessandro Manzoni" General Hospital, Via Dell'Eremo 9/11, 23900, Lecco, Italy.

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http://dx.doi.org/10.1007/s10072-020-04539-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323876PMC
June 2020
1.495 Impact Factor

Cerebral venous sinus thrombosis in a patient with appendicular abscess: a case report.

World Neurosurg 2020 Jun 26. Epub 2020 Jun 26.

Department of Neurosurgery, Shengzhou People's Hospital (the First Affiliated Hospital of Zhejiang University Shengzhou Branch).

Background: Acute appendicitis is a common abdominal emergency, while cerebral venous sinus thrombosis (CVST) is a rare cerebral vascular disease. Cases of CVST in patients with appendicitis have not been reported in literature.

Case Description: Here we reported a case of CVST in a patient with appendicular abscess. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.06.183DOI Listing

[Brain MRI-findings in Ph - negative myeloproliferative disorders].

Ter Arkh 2019 Jul 15;91(7):29-34. Epub 2019 Jul 15.

Research center of Neurology.

Myeloproliferative disorders (MPD) are accompanied by a high proportion of thrombotic complications, which may lead to cerebrovascular disease (CVD).

Aim: To describe MRI-findings in patients with Ph - negative MPD and evaluate any cerebrovascular disease.

Materials And Methods: We included 104 patients with Ph - negative MPD (age varied between 20 and 58) with clinical correlates of cerebrovascular pathology. Read More

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http://dx.doi.org/10.26442/00403660.2019.07.000329DOI Listing

Cerebral venous thrombosis: report of 2 cases of hemorrhagic venous infarction.

Radiol Case Rep 2020 Aug 18;15(8):1295-1300. Epub 2020 Jun 18.

Department of Radiology, University Hospital Gabriel Montpied, Clermont Ferrand, France.

Cerebral venous thrombosis (CVT), a rare but potentially severe cerebrovascular disease, is defined as the thrombosis of a cortical or deep cerebral vein, or a cerebral venous sinus. This article reports 2 cases of CVT. In the first case, the patient is a 40-year-old woman with a history of 2 miscarriages, using oral contraception and presenting intense headache, cervical irradiation, and drowsiness. Read More

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http://dx.doi.org/10.1016/j.radcr.2020.05.009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306535PMC

Cerebral Venous Thrombosis in a Patient with Immune Thrombocytopenia, an Apparent Paradox.

Case Rep Oncol 2020 May-Aug;13(2):588-594. Epub 2020 Jun 4.

Department of Medical Oncology, National Centre for Cancer Care and Research, Hamad Medical Corporation, Doha, Qatar.

We present a paradoxical case of immune thrombocytopenia (ITP) that presented with cerebral venous thrombosis. A 39-year-old female patient diagnosed with chronic ITP, who failed treatment on multiple-line agents, was started on eltrombopag (thrombopoietin receptor agonist), which she was not compliant to. The patient later developed extensive cerebral venous thrombosis, along with venous infarcts, and intracranial and subarachnoid hemorrhage. Read More

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http://dx.doi.org/10.1159/000507389DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7315189PMC

Role of diffusion-weighted imaging in the diagnosis of cerebral venous thrombosis.

J Int Med Res 2020 Jun;48(6):300060520933448

Department of Neurology, Chinese PLA General Hospital, Beijing, China.

Objective: To evaluate the hyperintense signal (HIS) performance on diffusion-weighted imaging (DWI) in diagnosing cerebral venous thrombosis (CVT).

Methods: Seventy-eight patients with CVT hospitalized from January 2004 to January 2015 were retrospectively studied alongside 78 controls without intracranial organic diseases. Diagnostic accuracy indices of HIS on DWI or T2-weighted imaging (T2WI) to diagnose CVT at different sites and states were analyzed. Read More

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http://dx.doi.org/10.1177/0300060520933448DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7323280PMC

Prognostic value of systemic immune-inflammation index in acute/subacute patients with cerebral venous sinus thrombosis.

Stroke Vasc Neurol 2020 Jun 24. Epub 2020 Jun 24.

Department of Neurology, Zhengzhou University First Affiliated Hospital, Zhengzhou, Henan, China

Objective: To evaluate the prognosis values of systemic immune-inflammation index (SII) in non-chronic cerebral venous sinus thrombosis (CVST).

Methods: patients with CVST, admitted to the First Affiliated Hospital of Zhengzhou University, were retrospectively identified from January 2013 to December 2018. We selected patients in acute/subacute phase from database. Read More

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http://dx.doi.org/10.1136/svn-2020-000362DOI Listing

Diagnosis of large, mobile thrombus in transit within a patent foramen ovale by echocardiography.

Cardiol J 2020 ;27(3):325-326

Division of Cardiology, Department of Internal Medicine, Yeungnam University Medical Center, Daegu, Korea, Republic Of.

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http://dx.doi.org/10.5603/CJ.2020.0086DOI Listing
January 2020

Four cases of Trousseau syndrome associated with breast cancer that exhibited central nervous system manifestations.

Int Cancer Conf J 2020 Jul 4;9(3):146-150. Epub 2020 Apr 4.

Department of Breast-Thyroid-Endocrine Surgery, Faculty of Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki Japan.

Cancer-associated thrombosis is known as Trousseau syndrome (TS). Here, we report 4 cases of TS associated with advanced breast cancer that caused central nervous system (CNS) vascular events. All 4 patients experienced sudden onset of CNS symptoms. Read More

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http://dx.doi.org/10.1007/s13691-020-00411-9DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7297874PMC

Venous thromboembolism prevention in intracerebral hemorrhage: A systematic review and network meta-analysis.

PLoS One 2020 24;15(6):e0234957. Epub 2020 Jun 24.

Division of Neurology, Department of Medicine, University of Ottawa, Ottawa, Canada.

Introduction: To summarize and compare the effectiveness of pharmacological thromboprophylaxis to pneumatic compression devices (PCD) for the prevention of venous thromboembolism in patients with acute intracerebral hemorrhage.

Methods: MEDLINE, PUBMED, EMBASE, and CENTRAL were systematically searched to identify randomized and non-randomized studies that compared each intervention directly to each other or against a common control (hydration, anti-platelet agents, stockings) in adults with acute spontaneous intracerebral hemorrhage. Two investigators independently screened the studies, extracted data, and appraised risk of bias. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0234957PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7314010PMC

Prediction of Cerebral Venous Thrombosis with a new clinical score and D-dimer levels.

Neurology 2020 Jun 23. Epub 2020 Jun 23.

Department of Neurology, Inselspital, University Hospital and University of Bern, Switzerland.

Objective: To investigate prediction of cerebral venous thrombosis (CVT) by clinical variables and D-dimer levels.

Methods: This prospective multicentre study included consecutive patients with clinically possible CVT. On admission, patients underwent clinical examination, blood-sampling for D-dimers-measuring (ELISA-test), and MR-/CT-venography. Read More

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http://dx.doi.org/10.1212/WNL.0000000000009998DOI Listing

Features of intracranial hemorrhage in cerebral venous thrombosis.

J Neurol 2020 Jun 22. Epub 2020 Jun 22.

Stroke Division, Florey Institute of Neuroscience and Mental Health, University of Melbourne, 245 Burgundy Street, Heidelberg, VIC, 3084, Australia.

Background: Cerebral venous thrombosis (CVT) is associated with intracranial hemorrhage.

Aim: To identify clinical and imaging features of CVT-associated intracranial hemorrhage. We hypothesized that higher clot burden would be associated with a higher risk of intracranial hemorrhage. Read More

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http://dx.doi.org/10.1007/s00415-020-10008-0DOI Listing

Consensus Guidelines of the French Society of Neuroradiology (SFNR) on the use of Gadolinium-Based Contrast agents (GBCAs) and related MRI protocols in Neuroradiology.

J Neuroradiol 2020 06 18. Epub 2020 Jun 18.

MRI center, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France; Université Lyon 1, CREATIS-LRMN, CNRS/UMR/5220-INSERM U630, Villeurbanne, France.

Gadolinium-based contrast agents (GBCAs) are used in up to 35% of magnetic resonance imaging (MRI) examinations and are associated with an excellent safety profile. Nevertheless, two main issues have arisen in the last two decades: the risk of nephrogenic systemic fibrosis and the risk of gadolinium deposition and retention. As a first step, this article reviews the different categories of GBCAs available in neuroradiology, their issues, and provides updates regarding the use of these agents in routine daily practice. Read More

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http://dx.doi.org/10.1016/j.neurad.2020.05.008DOI Listing

[An hereditary hemorrhagic telangiectasia of late revealed by a cerebral venous thrombosis: A case report].

Rev Med Interne 2020 Jun 19. Epub 2020 Jun 19.

Service de médecine vasculaire, CHU de Nantes, Boulevard Jacques Monod, 44093 Nantes cedex 1, France.

Introduction: Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disease characterized by the triad of nose bleeding, telangiectasia and familial heredity.

Case Report: We report the case of a patient who had idiopathic venous cerebral thrombosis complicated by a cerebral infarction treated with warfarin. In the context of a psoas hematoma by warfarine overdose and immobilization, the patient had deep vein thrombosis of the left lower limb with pulmonary embolism revealing a pulmonary arteriovenous malformation. Read More

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http://dx.doi.org/10.1016/j.revmed.2020.03.013DOI Listing

Bilateral corpus callosum and corona radiata infarction due to cerebral venous sinus thrombosis presenting as headache and acute reversible aphasia: a rare case report.

BMC Neurol 2020 Jun 19;20(1):249. Epub 2020 Jun 19.

Cerebral Palsy Rehabilitation Department, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, 450000, Henan, China.

Background: Cerebral venous sinus thrombosis (CVST), a rare cause of cerebral infarction, is often unrecognized at initial presentation. We report the case of a patient with bilateral corpus callosum and corona radiata infarction due to cerebral venous sinus thrombosis presenting as headache and acute reversible aphasia.

Case Presentation: A 30-year-old female patient presented with headache, vomiting, and motor aphasia. Read More

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http://dx.doi.org/10.1186/s12883-020-01829-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7304224PMC

Incidence of Antithrombin Deficiency and Anti-Cardiolipin Antibodies After Severe Traumatic Brain Injury: A Prospective Cohort Study.

Neurocrit Care 2020 Jun 18. Epub 2020 Jun 18.

Department of Intensive Care Medicine, Royal Perth Hospital, ICU, 4th Floor, North Block, Wellington Street, Perth, WA, 6000, Australia.

Background: Animal studies suggested that cerebral mitochondrial cardiolipin phospholipids were released after severe traumatic brain injury (TBI), contributing to the pathogenesis of thromboembolism.

Objectives: To determine the incidence of anti-cardiolipin antibodies after severe TBI and whether this was related to the severity of TBI and development of venous thromboembolism.

Methods: Serial anti-cardiolipin antibodies, antithrombin levels, viscoelastic testing, and coagulation parameters were measured on admission, day-1, and between day-5 and day-7 in patients with severe TBI requiring intracranial pressure monitoring. Read More

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http://dx.doi.org/10.1007/s12028-020-01026-xDOI Listing
June 2020
2.440 Impact Factor

Anticoagulation delay does not affect the functional outcome of cerebral venous thrombosis.

Aging (Albany NY) 2020 Jun 18;12(12):11835-11842. Epub 2020 Jun 18.

China-America Institute of Neuroscience, Xuanwu Hospital, Capital Medical University, Beijing 100053, China.

Available knowledge about the impact of anticoagulation delay on outcomes of patients with cerebral venous thrombosis (CVT) is limited. We therefore assessed the factors influencing anticoagulation delay and investigated the effect of this delay on outcomes of CVT patients. Anticoagulation delay was defined as the time interval between symptom onset and anticoagulation initiation. Read More

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http://dx.doi.org/10.18632/aging.103353DOI Listing

Cerebral Venous Thrombosis Associated with COVID-19.

AJNR Am J Neuroradiol 2020 Jun 18. Epub 2020 Jun 18.

From the Departments of Radiology (D.D.C., E.R., M.S., S.D., R.J., A.R., P.K.N.).

Despite the severity of coronavirus disease 2019 (COVID-19) being more frequently related to acute respiratory distress syndrome and acute cardiac and renal injuries, thromboembolic events have been increasingly reported. We report a unique series of young patients with COVID-19 presenting with cerebral venous system thrombosis. Three patients younger than 41 years of age with confirmed Severe Acute Respiratory Syndrome coronavirus 2 (SARS-Cov-2) infection had neurologic findings related to cerebral venous thrombosis. Read More

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http://dx.doi.org/10.3174/ajnr.A6644DOI Listing

Atypical Deep Cerebral Vein Thrombosis with Hemorrhagic Venous Infarction in a Patient Positive for COVID-19.

AJNR Am J Neuroradiol 2020 Jun 18. Epub 2020 Jun 18.

From the Service de Neuroradiologie (L.C., N.S.).

There is growing evidence that Severe Acute Respiratory Syndrome coronavirus 2 (SARS-CoV-2) has a neurotropic and neuroinvasive potential. In particular, neurologic complications associated with the infection by SARS-CoV-2 include strokes that may result from a dysregulated inflammatory response to the infection. We report an atypical deep cerebral vein thrombosis complicated with hemorrhagic venous infarction in a patient positive for SARS-CoV-2 with no risk factors for thrombosis. Read More

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http://dx.doi.org/10.3174/ajnr.A6642DOI Listing

Risk factors for pediatric cerebral sinovenous thrombosis: A case-control study with case validation.

Thromb Res 2020 Jun 9;194:8-15. Epub 2020 Jun 9.

Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD, USA; Johns Hopkins All Children's Institute for Brain Protection Sciences, St. Petersburg, FL, USA; Department of Neurosurgery, Geisinger Medical Center, Danville, PA, USA; Department of Neuroscience, Geisinger Commonwealth School of Medicine, Scranton, PA, USA.

Introduction: Cerebral sinovenous thrombosis (CSVT) represents the second most common type of venous thromboembolism (VTE) in children. Current literature includes limited evidence on risk factors for CSVT, particularly in the pediatric population. We sought to determine risk factors for CSVT in pediatric patients through a single-institutional case-control study. Read More

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http://dx.doi.org/10.1016/j.thromres.2020.06.013DOI Listing

Use and Removal of Inferior Vena Cava Filters in Patients With Acute Brain Injury.

Neurohospitalist 2020 Jul 28;10(3):188-192. Epub 2020 Feb 28.

Clinical and Translational Neuroscience Unit, Feil Family Brain and Mind Research Institute, New York, NY, USA.

Background: Few data exist regarding the rate of inferior vena cava (IVC) filter retrieval among brain-injured patients.

Methods: We conducted a retrospective cohort study using inpatient claims between 2009 and 2015 from a nationally representative 5% sample of Medicare beneficiaries. We included patients aged ≥65 years who were hospitalized with acute brain injury. Read More

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http://dx.doi.org/10.1177/1941874420907531DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7271624PMC

Cerebral sinovenous thrombosis in pediatric hemolytic uremic syndrome.

Res Pract Thromb Haemost 2020 May 30;4(4):659-665. Epub 2020 Mar 30.

Division of Pediatric Hematology/Oncology Department of Pediatric and Adolescent Medicine Mayo Clinic Rochester Minnesota.

Hemolytic uremic syndrome (HUS) may result in thrombotic central nervous system complications. We present a child with diarrhea-associated HUS who developed new-onset focal seizures secondary to cerebral sinovenous thrombosis (CSVT). Her CSVT was treated with low-molecular-weight heparin. Read More

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http://dx.doi.org/10.1002/rth2.12329DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292672PMC

Increased risk of thrombotic events in cold agglutinin disease: A 10-year retrospective analysis.

Res Pract Thromb Haemost 2020 May 9;4(4):628-635. Epub 2020 Apr 9.

Bioverativ, a Sanofi company Waltham Massachusetts.

Background: Cold agglutinin disease (CAD) is a rare autoimmune hemolytic anemia mediated by IgM autoantibodies that trigger hemolysis via classical complement pathway. Increased incidence of thrombotic events (TEs) has been reported in patients with other forms of hemolysis. The incidence of TEs in patients with CAD is unknown. Read More

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http://dx.doi.org/10.1002/rth2.12333DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7292660PMC

Reversible cerebral vasoconstriction syndrome concomitant with cerebral venous sinus thrombosis following ovarian tumor resection: A report of two cases.

Surg Neurol Int 2020 30;11:128. Epub 2020 May 30.

Department of Neurosurgery, Kanazawa Medical Center, Shimoishibikimachi, Kanazawa, Ishikawa, Japan.

Background: Reversible cerebral vasoconstriction syndrome (RCVS) presents with characteristic clinical, brain imaging, and angiographic findings. The most common clinical feature of RCVS is a severe acute headache, which is often referred to as a thunderclap headache due to the nature of its presentation. It may occur spontaneously or may be provoked by various precipitating factors. Read More

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http://dx.doi.org/10.25259/SNI_578_2019DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7294317PMC

Brain MRI Findings in Severe COVID-19: A Retrospective Observational Study.

Radiology 2020 06 16:202222. Epub 2020 Jun 16.

Hôpitaux Universitaires de Strasbourg, Service d'imagerie 2, Hôpital de Hautepierre, Strasbourg, France (S.K., F.L., S.B., F.D.A., T.W.); Engineering science, computer science and imaging laboratory (ICube), Integrative Multimodal Imaging in Healthcare, UMR 7357, University of Strasbourg-CNRS, Strasbourg, France (S.K.,); Service de Neurologie, Hôpitaux Universitaires de Strasbourg, Strasbourg, France (J.S., C.B., V.M., M.A.); CHU Rennes, Department of Neuroradiology, Rennes, France (J.C.F., B.C.N.); Service de maladies infectieuses et réanimation médicale. CHU Rennes, France (A.M.); Hôpitaux universitaires de Strasbourg, Service d'Anesthésie-Réanimation, Nouvel Hôpital Civil, Strasbourg, France (O.C., P.M.M.); Service de Neuroradiologie, CHU Toulouse, Toulouse, France (F.B., G.A.); Department of infectious and tropical diseases, Toulouse University Hospital, Toulouse, France (G.M.B.); Department of Neurology, Toulouse University Hospital, Toulouse, France (M.R.); Department of Anesthesia and Critical Care, Toulouse University Hospital University Toulouse 3-Paul Sabatier, Toulouse, France (T.G., L.D.); Service de neuroradiologie diagnostique et interventionnelle, Centre Hospitalier Universitaire des Alpes, Grenoble, France (S.G., A.K.); Nephrology and Transplantation department, Hôpitaux Universitaires de Strasbourg. Inserm UMR S1109, LabEx Transplantex, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg, Strasbourg, France (S.C.); EA CHIMERE 7516, Université de Picardie Jules Verne, Amiens, France; Service de NeuroRadiologie, pôle Imagerie Médicale, Centre Hospitalo-Universitaire d'Amiens, Amiens, France (J.M.C., A.H.); Service de Neuro Radiologie, pôle Imagerie Médicale, Centre Hospitalo-Universitaire d'Amiens, Amiens, France (S.M.); Hôpitaux universitaires de Strasbourg, Service de Médecine Intensive Réanimation, Nouvel Hôpital Civil, Strasbourg, France (J.H., F.M.); Immuno-Rhumatologie Moléculaire, INSERM UMR_S1109, LabEx TRANSPLANTEX, Centre de Recherche d'Immunologie et d'Hématologie, Faculté de Médecine, Fédération Hospitalo-Universitaire (FHU) OMICARE, Fédération de Médecine Translationnelle de Strasbourg (FMTS), Université de Strasbourg (UNISTRA), Strasbourg, France (J.H.); Hôpitaux universitaires de Strasbourg, Service de Médecine Intensive Réanimation, Hautepierre, Strasbourg, France (M.S., F.C.); Service de Maladies infectieuses, NHC, CHU de Strasbourg, Strasbourg, France (N.L., Y.H.); Service de Radiologie, CHU de Saint-Etienne, Saint-Etienne, France (C.B.); Service de Réanimation, CH de Roanne, Roanne, France (X.F.); University Hospital of Limoges, Neuroradiology Department, Limoges, France (G.F., S.S.); Radiology Department, Hôpital Privé d'Antony, Antony, France (I.B., G.B.); Service d'imagerie Pédiatrique et Fœtale, Hôpital Femme Mère Enfant, HCL, Lyon, France (A.L.); Service de Neuroradiologie, Hôpitaux Civils de Colmar, Colmar, France (H.O., F.B., J.M.); INSERM U1266, Service d'imagerie morphologique et fonctionnelle, GHU Psychiatrie et Neurosciences, site Sainte-Anne, Paris, France (G.H., J.B., C.O., G.B., M.E.G., B.K.); service de Neuroradiologie, CHU Henri Mondor, Créteil, France (B.B., I.M.); Neuroradiology Unit, Department of Radiology, Assistance Publique-Hôpitaux de Paris (APHP), Bichat University Hospital, Paris, France (M.H.F., A.G.); Department of Radiology, Assistance Publique-Hôpitaux de Paris (APHP), Denis Diderot University and Medical School, Bichat University Hospital, Paris, France (A.K.); CHIC Unisanté, Hôpital Marie Madeleine, Forbach, France (L.J., P.N., Y.T.M.); service de Radiologie 1, GHR Mulhouse Sud Alsace, Hôpital Mère Enfants, Mulhouse, France (C.H., P.F., N.S.); Service de Neurologie, Centre Hospitalier de Haguenau, Haguenau, France (S.C., C.L.); Service de Radiologie, Centre Hospitalier de Haguenau, Haguenau, France (M.A.); Service de Neuroradiologie, Hôpital Central, CHU de Nancy, Nancy, France (E.S., R.A., F.Z.); Department of Neuroradiology, University Hospital of Dijon, Hôpital François Mitterrand, Dijon, France (P.C., F.R., P.T.); Department of Diagnostic and Interventional Neuroradiology, University Hospital, Nantes, France (H.D.); Neuroradiology department - CHU de Bordeaux, Bordeaux, France (J.B.); Service de Neuroradiologie, CHU de Lille, Lille, France (A.K.); Assistance Publique Hôpitaux de Paris, Service de Neuroradiologie, Hôpital Pitié-Salpêtrière, Paris, France Sorbonne Université, Univ Paris 06, UMR S 1127, CNRS UMR 7225, ICM, F-75013, Paris, France (N.P.); Neuroradiology department, Fondation A.Rothschild Hospital, Paris, France (A.L.); Hôpitaux Universitaires de Strasbourg, UCIEC, Pôle d'Imagerie, Strasbourg, France (P.E.Z., M.M.); Observatoire Français de la Sclérose en Plaques, Lyon, France (J.C.B.); Hôpitaux universitaires de Strasbourg, Laboratoire de Virologie Médicale, Strasbourg, France (S.F.K.); Radiology Department, Nouvel Hôpital Civil, Strasbourg University Hospital, Strasbourg, France (M.O.); INSERM (French National Institute of Health and Medical Research), UMR 1260, Regenerative Nanomedicine (RNM), FMTS, Strasbourg, France (F.M.); Department of Anaesthesia and Intensive Care, Lyon-Sud Hospital, Hospices Civils de Lyon, F-69495 Pierre Benite; University Claude Bernard Lyon 1, Lyon, France (J.S.D.); CHU de Strasbourg, Service de Santé Publique, GMRC, F-67091 Strasbourg, France (N.M.); Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), INSERM-U964/CNRSUMR7104/Université de Strasbourg, Illkirch, France (M.A.); MRI center, Centre Hospitalier Lyon Sud, Hospices Civils de Lyon, Lyon, France (F.C.); Université Lyon 1, CREATIS-LRMN, CNRS/UMR/5220-INSERM U630, Villeurbanne, France (F.C.).

Background Brain MRI parenchymal signal abnormalities have been in association with SARS-CoV-2. Purpose Describe the neuroimaging findings (excluding ischemic infarcts) in patients with severe COVID-19 infection. Methods This was a retrospective study of patients evaluated from March 23th, 2020 to April 27th, 2020 at 16 hospitals. Read More

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http://dx.doi.org/10.1148/radiol.2020202222DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7301613PMC

Cryptogenic cerebral venous thrombosis in a multiple-sclerosis-patient treated with Alemtuzumab.

Mult Scler Relat Disord 2020 May 30;44:102246. Epub 2020 May 30.

Regional Epilepsy Centre, Great Metropolitan Hospital, Reggio Calabria, Italy; Department of Medical and Surgical Sciences, Magna Graecia University of Catanzaro, Italy.

Alemtuzumab is a highly effective treatment for relapsing-remitting multiple sclerosis (MS). Its molecular target is CD 52, a GPI-anchored protein. Herein, we describe the case of a 40-year-old man with MS treated with alemtuzumab, who developed cerebral sinus thrombosis. Read More

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http://dx.doi.org/10.1016/j.msard.2020.102246DOI Listing

[A case of cerebral venous sinus thrombosis mimicking transient ischemic attack].

Rinsho Shinkeigaku 2020 Jun 13. Epub 2020 Jun 13.

Department of Neurology, Kumamoto Rosai Hospital.

A 48-year-old woman with a right-sided headache beginning a month prior to admission presented with sudden-onset right hemiparesis. On admission, she had weakness of the right lower extremity, which disappeared 3 hours after onset. Contrast enhanced brain MRI revealed no parenchymal lesion, while indicated thrombi in the superior sagittal sinus and the right side of the transverse sinus, sigmoid sinus, and internal jugular vein, leading to the diagnosis of cerebral venous sinus thrombosis. Read More

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http://dx.doi.org/10.5692/clinicalneurol.60.cn-001423DOI Listing

Isolated severe blunt traumatic brain injury: effect of obesity on outcomes.

J Neurosurg 2020 Jun 12:1-8. Epub 2020 Jun 12.

2Department of Surgery, Division of Trauma, Emergency Surgery, and Surgical Critical Care, LAC+USC Medical Center, University of Southern California, Los Angeles, California.

Objective: Obesity has been widely reported to confer significant morbidity and mortality in both medical and surgical patients. However, contemporary data indicate that obesity may confer protection after both critical illness and certain types of major surgery. The authors hypothesized that this "obesity paradox" may apply to patients with isolated severe blunt traumatic brain injuries (TBIs). Read More

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http://dx.doi.org/10.3171/2020.3.JNS193458DOI Listing

Deep Cerebral Venous Thrombosis Treatment : Endovascular Case using Aspiration and Review of the Various Treatment Modalities.

Clin Neuroradiol 2020 Jun 11. Epub 2020 Jun 11.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

Background: Deep cerebral venous thrombosis (CVT) is an uncommon condition with a high morbidity and mortality. The optimal treatment approach for deep CVT remains uncertain and due to its low prevalence, randomized trials are not feasible. We showcase a straight sinus thrombosis treated with a large bore aspiration and performed a meta-analysis of the available literature to characterize and evaluate the various treatment modalities for patients with deep CVT. Read More

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http://dx.doi.org/10.1007/s00062-020-00920-3DOI Listing

Cerebral venous thrombosis induced by intravaginal estrogen ring: A lingering adverse reaction on hemostasis.

Niger J Clin Pract 2020 Jun;23(6):887-888

Associate Professor of Neurology, Department of Internal Medicine, Saudi Arabia.

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http://dx.doi.org/10.4103/njcp.njcp_223_19DOI Listing

Cryptogenic stroke over 60 years of age: should patent foramen ovale be closed?

Eur Heart J Suppl 2020 Jun 30;22(Suppl E):E82-E86. Epub 2020 Mar 30.

U.O.C. Cardiologia, Ospedale S. Eugenio, Roma.

Patent foramen ovale (PFO) is an anatomical communication between the left and the right atrium due to the lack of completed sealing of the fossa ovalis. Epidemiologic data, for the most part derived from young populations studies, suggested that PFO, allowing paradoxical embolization of thrombotic material from the venous to the arterial district, could play a significant role in the pathogenesis of cryptogenic ischaemic cerebral events. Recently, three randomized studies in patients ≤60 years of age demonstrated the superiority of percutaneous closure of PFO over medical antithrombotic treatment. Read More

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http://dx.doi.org/10.1093/eurheartj/suaa067DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7270899PMC

Venous Thromboembolism in Geriatric Trauma Patients-Risk Factors and Associated Outcomes.

J Surg Res 2020 Jun 7;254:327-333. Epub 2020 Jun 7.

Section of Trauma and Acute Care Surgery, Department of Surgery, Westchester Medical Center, New York Medical College, Valhalla, New York.

Background: Venous thromboembolism (VTE) places elderly trauma patients at a high risk of morbidity. The purpose of this study was to determine the outcomes related to VTE in geriatric trauma patients, as well as to identify risk factors for the development of VTE in this population. We also assessed the impact of the type and timing of VTE prophylaxis, and the type of injuries, on development of VTE in geriatric trauma population. Read More

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http://dx.doi.org/10.1016/j.jss.2020.05.008DOI Listing

Antiphospholipid syndrome and its role in pediatric cerebrovascular diseases: A literature review.

World J Clin Cases 2020 May;8(10):1806-1817

Department of Paediatric Neurology, School of Medicine in Katowice, Medical University of Silesia in Katowice, Sosnowiec 41200, Poland.

Antiphospholipid syndrome (APS) or Hughes syndrome is an acquired thromboinflammatory disorder. Clinical criteria of APS diagnosis are large- and small-vessel thrombosis as well as obstetric problems; laboratory criteria are the presence of antiphospholipid antibodies (lupus anticoagulant, anticardiolipin antibodies and anti-β2-glycoprotein-1). The presence of at least 1 clinical and 1 laboratory criterion allows definitive diagnosis of APS. Read More

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http://dx.doi.org/10.12998/wjcc.v8.i10.1806DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7262698PMC

COVID-19: A Global Threat to the Nervous System.

Ann Neurol 2020 07;88(1):1-11

Department of Neurology, Medicine, and Immunology-Microbiology, University of Colorado School of Medicine, Aurora, CO, USA.

In less than 6 months, the severe acute respiratory syndrome-coronavirus type 2 (SARS-CoV-2) has spread worldwide infecting nearly 6 million people and killing over 350,000. Initially thought to be restricted to the respiratory system, we now understand that coronavirus disease 2019 (COVID-19) also involves multiple other organs, including the central and peripheral nervous system. The number of recognized neurologic manifestations of SARS-CoV-2 infection is rapidly accumulating. Read More

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http://dx.doi.org/10.1002/ana.25807DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300753PMC

Concomitant brain arterial and venous thrombosis in a COVID-19 patient.

Eur J Neurol 2020 Jun 5. Epub 2020 Jun 5.

Department of Neurology and Regional Referral Multiple Sclerosis Centre, University-Hospital San Luigi, Orbassano, Italy.

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http://dx.doi.org/10.1111/ene.14380DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7300879PMC

Cerebral ischemic and hemorrhagic complications of coronavirus disease 2019.

Int J Stroke 2020 Jun 26:1747493020937189. Epub 2020 Jun 26.

Department of Neurological Surgery, Thomas Jefferson University Hospital, Philadelphia, USA.

Background: The coronavirus disease 2019 is associated with neurological manifestations including stroke.

Objectives: We present a case series of coronavirus disease 2019 patients from two institutions with acute cerebrovascular pathologies. In addition, we present a pooled analysis of published data on large vessel occlusion in the setting of coronavirus disease 2019 and a concise summary of the pathophysiology of acute cerebrovascular disease in the setting of coronavirus disease 2019. Read More

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http://dx.doi.org/10.1177/1747493020937189DOI Listing

Not Just Another Headache: Cerebral Venous Sinus Thrombosis in a Patient With Isolated Antithrombin III Deficiency.

Cureus 2020 May 31;12(5):e8383. Epub 2020 May 31.

Internal Medicine, Kirksville College of Osteopathic Medicine, A. T. Still University, Kirksville, USA.

Cerebral venous sinus thrombosis (CVST) is a rare condition. Symptoms and signs arise from a combination of thrombosis of cerebral veins and increased intracranial pressure. The most common presenting symptom is a non-descriptive headache, but presentation varies with underlying etiology. Read More

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http://dx.doi.org/10.7759/cureus.8383DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265752PMC