28,220 results match your criteria Cerebral Palsy


FOOD INTAKE, NUTRITIONAL STATUS AND GASTROINTESTINAL SYMPTOMS IN CHILDREN WITH CEREBRAL PALSY.

Arq Gastroenterol 2018 Oct-Dec;55(4):352-357

Universidade Federal de São Paulo, Escola Paulista de Medicina, Disciplina de Gastroenterologia Pediátrica, São Paulo, SP, Brasil.

Background: Cerebral palsy may be associated with comorbidities such as undernutrition, impaired growth and gastrointestinal symptoms. Children with cerebral palsy exhibit eating problems due to the effect on the anatomical and functional structures involved in the eating function resulting in malnutrition.

Objective: The aim of this study was to investigate the association between food intake, nutritional status and gastrointestinal symptoms in children with cerebral palsy. Read More

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http://dx.doi.org/10.1590/S0004-2803.201800000-78DOI Listing

Atrial standstill presenting as cerebral infarction in a 7-year-old girl.

SAGE Open Med Case Rep 2019 4;7:2050313X19827735. Epub 2019 Feb 4.

Department of Pediatrics, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark.

Atrial standstill is a rare arrhythmia defined by the absence of mechanical and electrical activity in the atria. Few cases of atrial standstill have been described in children, none of which have presented with cerebral infarction confirmed by imaging. We report a unique case of a 7-year-old girl presenting with expressive aphasia, central facial palsy and irregular pulse with cerebral infarction secondary to atrial standstill. Read More

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http://dx.doi.org/10.1177/2050313X19827735DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6366293PMC
February 2019

Children with Hemiparesis Arm and Movement Project (CHAMP): protocol for a multisite comparative efficacy trial of paediatric constraint-induced movement therapy (CIMT) testing effects of dosage and type of constraint for children with hemiparetic cerebral palsy.

BMJ Open 2019 Jan 15;9(1):e023285. Epub 2019 Jan 15.

University of Virginia, Charlottesville, Virginia, USA.

Introduction: The Children with Hemiparesis Arm and Movement Project (CHAMP) addresses two pressing issues concerning paediatric constraint-induced movement therapy (CIMT): effects of two dosages and two types of constraint on functional outcomes. Systematic reviews conclude that CIMT is one of the most efficacious treatments, but wide variations in treatment protocols, outcome measures and patient characteristics have prevented conclusions about potential effects of dosage levels and constraint methods.

Methods And Analysis: CHAMP is a multisite comparative efficacy randomised controlled trial of 135 children (2-8 years) with hemiparetic cerebral palsy. Read More

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http://dx.doi.org/10.1136/bmjopen-2018-023285DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6340418PMC
January 2019

Associations between use of macrolide antibiotics during pregnancy and adverse child outcomes: A systematic review and meta-analysis.

PLoS One 2019 19;14(2):e0212212. Epub 2019 Feb 19.

Population, Policy and Practice Programme, Great Ormond Street Institute of Child Health, University College London, London, United Kingdom.

Background: Evidence on adverse effects of maternal macrolide use during pregnancy is inconsistent. We conducted a systematic review and meta-analysis to investigate the association between macrolide use during pregnancy and adverse fetal and child outcomes.

Methods And Findings: We included observational studies and randomised controlled trials (RCTs) that recorded macrolide use during pregnancy and child outcomes. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0212212PLOS
February 2019

Association Between the Elasticity of Hip Muscles and the Hip Migration Index in Cerebral Palsy.

J Ultrasound Med 2019 Feb 18. Epub 2019 Feb 18.

Department of Radiology, Baskent University Faculty of Medicine, Adana, Turkey.

Objectives: Cerebral palsy (CP) increases the risk of hip displacement during childhood. Abnormal hip muscle forces have been proposed as the predisposing factors. In CP, the amount of hip displacement is commonly evaluated by the Reimers hip migration index (MI) on an anteroposterior pelvic radiograph. Read More

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http://dx.doi.org/10.1002/jum.14969DOI Listing
February 2019

Characterization of torque generating properties of ankle plantar flexor muscles in ambulant adults with cerebral palsy.

Eur J Appl Physiol 2019 Feb 18. Epub 2019 Feb 18.

Department of Neuroscience, University of Copenhagen, Blegdamsvej 3, 2200, Copenhagen N, Denmark.

Purpose: Weakness of plantar flexor muscles is related to reduced push-off and forward propulsion during gait in persons with cerebral palsy (CP). It has not been clarified to what an extent altered muscle contractile properties contribute to this muscle weakness. Here, we investigated the torque generating capacity and muscle fascicle length in the triceps surae muscle throughout ankle range of motion (ROM) in adults with CP using maximal single muscle twitches elicited by electrical nerve stimulation and ultrasonography. Read More

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http://dx.doi.org/10.1007/s00421-019-04102-zDOI Listing
February 2019

[Long-term results of chronic intrathecal baclofen treatment in patients with spasticity and secondary dystonia].

Zh Nevrol Psikhiatr Im S S Korsakova 2019 ;119(1):38-43

Pirogov Russian National Research Medical University, Moscow, Russia.

Aim: To estimate the efficacy of intrathecal treatment with baclofen (ITB) in spasticity and dystonia.

Material And Methods: Two groups of patients have been operated: 19 patients with spinal spasticity and 33 patients with cerebral spasticity (cerebral palsy). After baclofen screening test, the Synchromed2 (Medtronic) was implanted. Read More

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http://dx.doi.org/10.17116/jnevro201911901138DOI Listing
January 2019

[Follow-up recommendations for the late preterm infant].

An Pediatr (Barc) 2019 Feb 15. Epub 2019 Feb 15.

Grupo SEN34-36/ACUNA, Sociedad Española de Neonatología, España; Servicio de Pediatría-Neonatología, SCIAS, Hospital Barcelona, Barcelona, España.

The population of late preterm infants (PT), those born between 34+0 and 36+6 weeks of gestation, accounts for 70-74% of all premature infants, and is not specifically included in most of the follow-up protocols for preterm infants. For many years, PTs have been handled as if they were term newborns, which has led to a limited knowledge of their outcome in the medium and long term. Their neonatal morbidity is associated with a higher incidence of postnatal complications, with an increased rate of hospital re-admissions due to malnutrition, hyperbilirubinaemia, and respiratory problems, when compared to term infants. Read More

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http://dx.doi.org/10.1016/j.anpedi.2019.01.008DOI Listing
February 2019

Cerebral palsy among children of immigrants in Denmark and the role of socioeconomic status.

Eur J Paediatr Neurol 2019 Feb 4. Epub 2019 Feb 4.

Department of Public Health at University of Copenhagen, Oesterfarimagsgade 5, Postboks 2099, 1014 Copenhagen, Denmark.

Background: Children of immigrants in Denmark have excess risk for some of the most well-established risk factors for cerebral palsy (CP).

Objectives: To study differences in risk of CP between children of immigrants and children of Danish-born mothers, and explore whether socioeconomic status drives any potential association.

Methods: A register-based cohort study including 1,274,616 children born in Denmark between 1981 and 2007. Read More

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http://dx.doi.org/10.1016/j.ejpn.2019.01.007DOI Listing
February 2019

Validity and reliability of the Persian ABILHAND-Kids in a sample of Iranian children with cerebral palsy.

Disabil Rehabil 2019 Feb 19:1-9. Epub 2019 Feb 19.

f Department of Physical Therapy , Augusta Regents University , Augusta , GA , USA.

Aim: To develop a Persian version of ABILHAND-Kids and to determine its reliability and validity in Persian-speaking children with cerebral palsy (CP).

Method: The ABILHAND-Kids questionnaire was translated into Persian language and cross-culturally adapted following guidelines. The Persian ABILHAND-Kids was administered to 50 parents of CP children. Read More

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http://dx.doi.org/10.1080/09638288.2018.1530307DOI Listing
February 2019

Upper limb impairments, process skills, and outcome in children with unilateral cerebral palsy.

Dev Med Child Neurol 2019 Feb 18. Epub 2019 Feb 18.

Royal Hobart Hospital, Hobart, TAS, Australia.

Aim: To examine the relationships between upper limb impairments and independence in self-care (ISC) in children with unilateral cerebral palsy (CP).

Method: One hundred and eight children with unilateral CP (46 females, 62 males; mean age 8y 7mo, SD 3y 9mo) recruited from a population register were assessed for upper limb muscle power, spasticity, sensation, motor control, and process skills, and for ISC as the functional outcome using structural equation modelling.

Results: The model showed good fit indices and explained 90% of the variance in ISC. Read More

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http://dx.doi.org/10.1111/dmcn.14185DOI Listing
February 2019

Effect of electrical stimulation on aspiration in children with cerebral palsy and dysphagia.

J Phys Ther Sci 2019 Jan 29;31(1):93-94. Epub 2019 Jan 29.

Department of Occupational Therapy, Kyunghee Medical Center: 23 Kyungheedae-ro, Dongdaemun-gu, Seoul, Republic of Korea.

[Purpose] This study aims to investigate the effect of electrical stimulation on aspiration in children with cerebral palsy and dysphagia. [Participants and Methods] Five children with cerebral palsy and dysphagia were recruited. Electrical stimulation was applied to the submental region targeting submental muscles. Read More

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https://www.jstage.jst.go.jp/article/jpts/31/1/31_jpts-2018-
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http://dx.doi.org/10.1589/jpts.31.93DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348171PMC
January 2019
8 Reads

Demographics and Risk Factors for Non-Accidental Orthopedic Trauma.

Clin Pediatr (Phila) 2019 Feb 16:9922819829045. Epub 2019 Feb 16.

1 Rainbow Babies and Children's Hospital, University Hospitals Cleveland Medical Center, Cleveland, OH, USA.

Childhood non-accidental trauma (NAT) is the second most common cause of death in children. Despite its prevalence, NAT is frequently unreported due to provider misdiagnosis or unawareness. The purpose of this study was to determine current risk factors and injury patterns associated with NAT. Read More

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http://dx.doi.org/10.1177/0009922819829045DOI Listing
February 2019

Morphofunctional characteristics of skeletal muscle in rats with cerebral palsy.

Int J Exp Pathol 2019 Feb 17. Epub 2019 Feb 17.

Programa de Pós-Graduação em Biociências e Saúde, Universidade Estadual do Oeste do Paraná - UNIOESTE, Cascavel, Paraná, Brazil.

Knowledge of skeletal muscle adaptations is important to understand the functional deficits in cerebral palsy (CP). This study aimed to investigate the morphofunctional characteristics of skeletal muscle in a CP animal model. Initially, pregnant Wistar rats were injected intraperitoneally with saline or lipopolysaccharide over the last five days of pregnancy. Read More

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http://doi.wiley.com/10.1111/iep.12304
Publisher Site
http://dx.doi.org/10.1111/iep.12304DOI Listing
February 2019
1 Read

Ultrasound-Guided Botulinum Toxin Injections into the Salivary Glands for the Treatment of Drooling.

Isr Med Assoc J 2019 Feb;21(2):116-119

Department of Oral and Maxillofacial Surgery, Sheba Medical Center, Tel Hashomer, affiliated with Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Drooling is the unintentional loss of saliva from the mouth, usually caused by poor coordination of the swallowing mechanism. It is commonly seen in patients with chronic neurologic disorders, such as Parkinson's disease, amyotrophic lateral sclerosis (ALS), cerebral palsy, and stroke, as well as in patients with cognitive impairment and dementia.

Objectives: To evaluate the efficacy and safety of ultrasound-guided botulinum toxin injections into the parotid and submandibular salivary glands for the treatment of drooling. Read More

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February 2019
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Outcome of hand surgery in children with spasticity, a 9-year follow-up study.

J Pediatr Orthop B 2019 Feb 12. Epub 2019 Feb 12.

Department of Women's and Children's Health, Karolinska Institutet.

To evaluate whether short-term positive effects on bimanual function after surgery of the paretic arm in cerebral palsy are maintained long term. Assisting Hand Assessment (AHA) and active range of motion was tested before surgery and at 7 month and 9-year follow-up (n=18). AHA improved significantly from 50 to 52 U at 7 months, but was not different from before surgery at the 9-year follow-up, 49 U. Read More

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http://dx.doi.org/10.1097/BPB.0000000000000600DOI Listing
February 2019
1 Read

Opening the Door to Physical Activity for Children With Cerebral Palsy: Experiences of Participants in the BeFAST or BeSTRONG Program.

Adapt Phys Activ Q 2019 Feb 15:1-21. Epub 2019 Feb 15.

2 Holland Bloorview Kids Rehabilitation Hospital.

This study explored children's experiences of participating in one-to-one physical training programs to identify how programs can best promote physical activity participation for children with cerebral palsy. A qualitative descriptive design with self-determination theory was used. Semistructured interviews were conducted with 6 children with cerebral palsy, age 8-14 years, who participated in a fundamental-movement-skills or lower-limb strength-training program. Read More

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http://dx.doi.org/10.1123/apaq.2018-0048DOI Listing
February 2019
1 Read

A bio-psycho-social view of cerebral palsy: friendships reduce mental health disorders.

Authors:
Frank W Paulus

Dev Med Child Neurol 2019 Feb 14. Epub 2019 Feb 14.

Saarland University Hospital - Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Homburg/Saar, Germany.

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http://dx.doi.org/10.1111/dmcn.14200DOI Listing
February 2019
1 Read

High rates of malnutrition and epilepsy: two common comorbidities in children with cerebral palsy

Turk J Med Sci 2019 Feb 11;49(1):33-37. Epub 2019 Feb 11.

Background/aim: The aim of this study was to evaluate the nutritional status of children with cerebral palsy and determine the particular characteristics of the disorder.

Materials And Methods: The nutritional status of the children was assessed by the Gomez classification using weight-for-age. The Gross Motor Function Classification System was used to determine the gross and fine motor functions. Read More

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http://dx.doi.org/10.3906/sag-1803-79DOI Listing
February 2019
1 Read

Safety and efficacy of a propofol and ketamine based procedural sedation protocol in children with cerebral palsy undergoing botulinum toxin A injections.

PM R 2019 Feb 13. Epub 2019 Feb 13.

Division of Pediatric Critical Care Medicine, Indiana University School of Medicine, Riley Hospital for Children at Indiana University Health, Indianapolis, IN.

Background: Pediatric patients with cerebral palsy (CP) often undergo intramuscular botulinum toxin (BoNT-A) injections. These injections can be painful and may require procedural sedation. An ideal sedation protocol has yet to be elucidated. Read More

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http://dx.doi.org/10.1002/pmrj.12146DOI Listing
February 2019
1 Read

Reliability and responsiveness of the Jebsen-Taylor Test of Hand Function and the Box and Block Test for children with cerebral palsy.

Dev Med Child Neurol 2019 Feb 14. Epub 2019 Feb 14.

Institute of Neuroscience, Université catholique de Louvain, Brussels, Belgium.

Aim: To assess the reliability and to evaluate the responsiveness of both the Jebsen-Taylor Test of Hand Function (JTTHF) and the Box and Block Test (BBT) in children with cerebral palsy (CP).

Method: In this retrospective study, the reliability analyses were conducted with paired t-tests considering a short (mean 14d) and a long (mean 120d) time in between two assessment periods. In addition, an intraclass correlation coefficient (ICC) was used to assess the level of congruency. Read More

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http://dx.doi.org/10.1111/dmcn.14184DOI Listing
February 2019
1 Read

Cardiovascular disease in cerebral palsy: shifting our focus from attention to prevention.

Authors:
Patrick G McPhee

Dev Med Child Neurol 2019 Feb 14. Epub 2019 Feb 14.

Department of Pediatrics, McMaster University, Hamilton, Ontario, Canada.

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http://dx.doi.org/10.1111/dmcn.14198DOI Listing
February 2019
1 Read

Preoperative treatment of spasticity with botulinum neurotoxin A to reduce pain in cerebral palsy: is it worthwhile?

Authors:
Mark Gormley

Dev Med Child Neurol 2019 Feb 14. Epub 2019 Feb 14.

Gillette Children's Specialty Healthcare - Physical Medicine, Saint Paul, MN, USA.

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http://dx.doi.org/10.1111/dmcn.14191DOI Listing
February 2019
1 Read

Quantifying motor learning strategies can translate to physiotherapy dose for children with cerebral palsy.

Authors:
Helene M Dumas

Dev Med Child Neurol 2019 Feb 14. Epub 2019 Feb 14.

Medical/Rehabilitation Research Center, Franciscan Children's Hospital, Boston, MA, USA.

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http://dx.doi.org/10.1111/dmcn.14196DOI Listing
February 2019
1 Read

Effectiveness of Modified Constraint-Induced Movement Therapy Compared With Bimanual Therapy Home Programs for Infants With Hemiplegia: A Randomized Controlled Trial.

Am J Occup Ther 2018 Nov/Dec;72(6):7206205010p1-7206205010p9

Varda Gross-Tsur, PhD, MD, is Professor of Pediatrics, Neuropediatric Unit, Department of Pediatrics, Shaare Zedek Medical Center, Jerusalem, Israel, and the Hebrew University of Jerusalem, Jerusalem, Israel.

Objective: We examined the effectiveness of modified constraint-induced movement therapy (mCIMT) in treating infants with hemiplegic cerebral palsy and compared therapy outcomes with a nonconstraining bimanual therapy (BIM) of equal intensity.

Method: In a single-blinded randomized controlled trial, 33 infants with hemiplegia (mean corrected age = 11.1 mo, standard deviation = 2. Read More

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http://dx.doi.org/10.5014/ajot.2018.025981DOI Listing
February 2019
1 Read

Hereditary spastic paraplegia: a clinical and epidemiological study of a Brazilian pediatric population.

Arq Neuropsiquiatr 2019 Jan;77(1):10-18

Irmandade da Santa Casa de Misericórdia de São Paulo, São Paulo SP, Brasil.

Aims: To investigate hereditary spastic paraplegia (HSP) in a pediatric Brazilian sample.

Methods: Epidemiological, clinical, radiological and laboratory data were analyzed in 35 patients.

Results: Simple HSP (HSP-S) was detected in 12 patients, and complicated HSP (HSP-C) was detected in 23 patients. Read More

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http://dx.doi.org/10.1590/0004-282X20180153DOI Listing
January 2019
1 Read

Acute kwashiorkor in the setting of cerebral palsy and pancreatic insufficiency.

Cutis 2019 Jan;103(1):E10-E12

Department of Dermatology, Medical College of Georgia, Augusta University, USA.

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January 2019
1 Read

Correction to: Locomotion and cadence detection using a single trunk-fixed accelerometer: validity for children with cerebral palsy in daily life-like conditions.

J Neuroeng Rehabil 2019 Feb 12;16(1):27. Epub 2019 Feb 12.

Laboratory of Movement Analysis and Measurement, Ecole Polytechnique Fédérale de Lausanne (EPFL), Station 9, CH-1015, Lausanne, Switzerland.

The original article [1] contained a minor error whereby the middle initial of Christopher J. Newman's name was mistakenly omitted. Read More

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http://dx.doi.org/10.1186/s12984-019-0498-8DOI Listing
February 2019
1 Read

The health of children conceived by ART: 'the chicken or the egg?'

Hum Reprod Update 2019 Feb 12. Epub 2019 Feb 12.

Fertility Clinic, Rigshospitalet, Copenhagen University Hospital, Blegdamsvej 9, Copenhagen, Denmark.

Worldwide, more than 7 million children have now been born after ART: these delivery rates are steadily rising and now comprise 2-6% of births in the European countries. To achieve higher pregnancy rates, the transfer of two or more embryos was previously the gold standard in ART. However, recently the practise has moved towards a single embryo transfer policy to avoid multiple births. Read More

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http://dx.doi.org/10.1093/humupd/dmz001DOI Listing
February 2019
3 Reads

Emergent Prophylactic, Reparative and Restorative Brain Interventions for Infants Born Preterm With Cerebral Palsy.

Front Physiol 2019 28;10:15. Epub 2019 Jan 28.

The Discipline of Child and Adolescent Health, The Children's Hospital at Westmead Clinical School, The University of Sydney Medical School, Sydney, NSW, Australia.

Worldwide, an estimated 15 million babies are born preterm (<37 weeks' gestation) every year. Despite significant improvements in survival rates, preterm infants often face a lifetime of neurodevelopmental disability including cognitive, behavioral, and motor impairments. Indeed, prematurity remains the largest risk factor for the development of cerebral palsy. Read More

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http://dx.doi.org/10.3389/fphys.2019.00015DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360173PMC
January 2019
1 Read

Parent-reported sleep disorders in children with motor disabilities: a comparison with the Sleep Disturbance Scale for Children's new norms.

Sleep Med 2018 Dec 14;55:26-32. Epub 2018 Dec 14.

Pediatric Neurology and Neurorehabilitation Unit, Department of Pediatrics, University Hospital of Lausanne, Lausanne, Switzerland.

Objective: Children with motor disabilities such as cerebral palsy or neuromuscular diseases present more sleep disorders than their typically developing (TD) peers. However, research on these populations has always been performed using historical normative datasets or controls such as siblings. Therefore, we assessed the sleep quality of children with motor disabilities in comparison with a large, contemporary, general population sample. Read More

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http://dx.doi.org/10.1016/j.sleep.2018.11.016DOI Listing
December 2018
1 Read

High prevalence of pituitary hormone deficiency in both unilateral and bilateral optic nerve hypoplasia.

Acta Paediatr 2019 Feb 11. Epub 2019 Feb 11.

Department of Women's and Children's Health, Neuropediatric Unit, Karolinska Institutet, Stockholm, Sweden.

Aim: This study examined the prevalence of neurological impairment and pituitary hormone deficiency (PHD) in patients with unilateral and bilateral optic nerve hypoplasia (ONH).

Methods: A population-based cross-sectional cohort study of 65 patients (51% female) with ONH was conducted in Stockholm. Of these were 35 bilateral and 30 unilateral. Read More

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http://dx.doi.org/10.1111/apa.14751DOI Listing
February 2019
2 Reads

The Hand Assessment for Infants at risk for cerebral palsy.

Authors:
Margaret Wallen

Dev Med Child Neurol 2019 Feb 10. Epub 2019 Feb 10.

Occupational Therapy, School of Allied Health, Australian Catholic University, North Sydney, New South Wales, Australia.

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http://dx.doi.org/10.1111/dmcn.14183DOI Listing
February 2019
1 Read

Gait analysis for individually tailored interdisciplinary interventions in children with cerebral palsy: a randomized controlled trial.

Dev Med Child Neurol 2019 Feb 10. Epub 2019 Feb 10.

The Orthopaedic Research Unit, Department of Orthopaedic Surgery and Traumatology, Odense University Hospital, Odense, Denmark.

Aim: To test the hypothesis that improvements in gait and function following individualized interdisciplinary interventions consisting of physical therapy, orthotics, spasticity management, and orthopaedic surgery using instrumented gait analysis are superior to 'usual care' in children with cerebral palsy (CP).

Method: This was a prospective, single-blind, parallel-group, randomized controlled trial investigating the effectiveness of interventions based on the use of gait analysis. Primary outcome was gait (Gait Deviation Index) and secondary outcomes were walking and patient-reported outcome measures of function, disability, and health-related quality of life. Read More

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http://dx.doi.org/10.1111/dmcn.14178DOI Listing
February 2019
2 Reads

Reliability of the Motor Learning Strategies Rating Instrument in physiotherapy intervention for children with cerebral palsy.

Dev Med Child Neurol 2019 Feb 11. Epub 2019 Feb 11.

Bloorview Research Institute, Toronto, ON, Canada.

Aim: To evaluate the reliability of the Motor Learning Strategies Rating Instrument (MLSRI-20) in gait-based, video-recorded physiotherapy interventions for children with cerebral palsy (CP).

Method: Thirty videos of 18 children with CP, aged 6 to 17 years, participating in either traditional or Lokomat-based physiotherapy interventions were rated using the MLSRI-20. Physiotherapist raters provided general and item-specific feedback after rating each video, which was used when interpreting reliability results. Read More

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http://dx.doi.org/10.1111/dmcn.14177DOI Listing
February 2019
1 Read

Early Childhood Outcomes After Neonatal Encephalopathy in Uganda: A Cohort Study.

EClinicalMedicine 2018 Dec;6:26-35

Department of Paediatrics, Imperial College London, London, UK.

Background: Neonatal encephalopathy (NE) is a leading cause of global child mortality. Survivor outcomes in low-resource settings are poorly described. We present early childhood outcomes after NE in Uganda. Read More

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http://dx.doi.org/10.1016/j.eclinm.2018.12.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6358042PMC
December 2018
1 Read

MicroRNA Profile Differences in Neonates at Risk for Cerebral Palsy.

Phys Med Rehabil Int 2018 31;5(3). Epub 2018 May 31.

Department of Pediatrics, Northwestern University, USA.

Background: MicroRNAs; miRs are used as biomarkers in the diagnosis of several diseases. Cerebral palsy; CP, resulting from perinatal brain injury, cannot be diagnosed until 18-24 months old. Biomarkers to predict CP and assess response to investigational therapies are needed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6364989PMC
May 2018
2 Reads

Current thinking in the health care management of children with cerebral palsy.

Med J Aust 2019 Feb 10;210(3):129-135. Epub 2019 Feb 10.

Royal Children's Hospital Melbourne, Melbourne, VIC.

Cerebral palsy is a developmental disorder of movement and posture which is often associated with comorbidities. While there is currently a limited range of evidence-based treatments that change the underlying pathology of cerebral palsy, there are many areas in which health care professionals can change the natural history of cerebral palsy and improve participation and quality of life for children with this condition. Early identification has become of paramount importance in the management of cerebral palsy, and it is hoped that it will allow earlier access to cerebral palsy interventions that may improve the natural history of the condition. Read More

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http://dx.doi.org/10.5694/mja2.12106DOI Listing
February 2019
1 Read

Could the inhibitor of DNA binding 2 and 4 play a role in white matter injury?

Rev Neurosci 2019 Feb 9. Epub 2019 Feb 9.

Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

White matter injury (WMI) prevents the normal development of myelination, leading to central nervous system myelination disorders and the production of chronic sequelae associated with WMI, such as chronic dyskinesia, cognitive impairment and cerebral palsy. This results in a large emotional and socioeconomic burden. Decreased myelination in preterm infant WMI is associated with the delayed development or destruction of oligodendrocyte (OL) lineage cells, particularly oligodendrocyte precursor cells (OPCs). Read More

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http://dx.doi.org/10.1515/revneuro-2018-0090DOI Listing
February 2019
1 Read

Hip pain in children with cerebral palsy: a population-based registry study of risk factors.

BMC Musculoskelet Disord 2019 Feb 8;20(1):62. Epub 2019 Feb 8.

Lund University, Skåne University Hospital, Department of Clinical Sciences Lund, Orthopedics, Lund, Sweden.

Background: Hip pain is prevalent in children with cerebral palsy (CP). Hip displacement is a known risk factor for hip pain. However, many children do not have displaced hips but still have hip pain and the aetiologies are poorly understood. Read More

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http://dx.doi.org/10.1186/s12891-019-2449-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6368700PMC
February 2019
1 Read

"Now I am a techie too" - parental perceptions of using mobile technology for communication by children with complex communication needs in the Global South.

Disabil Rehabil Assist Technol 2019 Feb 8:1-12. Epub 2019 Feb 8.

c Cerebral Palsy Lanka Foundation , Colombo , Sri Lanka.

Purpose: Parental perceptions are key to the uptake of augmentative and alternative communication (AAC) devices for their children with complex communication needs. This study aimed to explore the perceptions of parents in a resource poor Global South country on the use of mobile technology as AAC devices.

Materials And Methods: Sixteen participants (11 female; 5 male) were included in the study. Read More

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http://dx.doi.org/10.1080/17483107.2018.1554713DOI Listing
February 2019
2 Reads

Interest of children with unilateral spastic cerebral palsy in bimanual daily activities.

Scand J Occup Ther 2019 Feb 8:1-9. Epub 2019 Feb 8.

b Department of Occupational Therapy and Graduate Program in Rehabilitation Sciences , Universidade Federal de Minas Gerais , Belo Horizonte , Minas Gerais , Brazil.

Background: Many bimanual activities are challenging for children with unilateral spastic cerebral palsy (USCP).

Aims: To investigate hand use by children with USCP in daily activities of their interest. Material e methods: Sample included twenty children with USCP, aged 8 to 14 years old. Read More

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https://www.tandfonline.com/doi/full/10.1080/11038128.2018.1
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http://dx.doi.org/10.1080/11038128.2018.1561938DOI Listing
February 2019
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Transcranial Direct Current Stimulation (tDCS) in Unilateral Cerebral Palsy: A Pilot Study of Motor Effect.

Neural Plast 2019 14;2019:2184398. Epub 2019 Jan 14.

Department of Developmental Neuroscience, IRCCS Fondazione Stella Maris, Calambrone, Pisa, Italy.

Transcranial Direct Current Stimulation (tDCS) is an emerging tool to improve upper limb motor functions after stroke acquired in adulthood; however, there is a paucity of reports on its efficacy for upper limb motor rehabilitation in congenital or early-acquired stroke. In this pilot study we have explored, for the first time, the immediate effects, and their short-term persistence, of a single application of anodal tDCS on chronic upper limb motor disorders in children and young individuals with Unilateral Cerebral Palsy (UCP). To this aim, in a crossover sham-controlled study, eight subjects aged 10-28 years with UCP underwent two sessions of and tDCS. Read More

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http://dx.doi.org/10.1155/2019/2184398DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6348802PMC
January 2019
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The Cerebral Palsy Profile of Health and Function: Upper-Extremity Domain's Sensitivity to Change Following Musculoskeletal Surgery.

J Hand Surg Am 2019 Feb 4. Epub 2019 Feb 4.

Department of Occupational Therapy, College of Rehabilitation Sciences, Thomas Jefferson University, Philadelphia, PA; Shriners Hospitals for Children, Philadelphia, PA.

Purpose: The Cerebral Palsy Profile of Health and Function (CP-PRO) Computerized Adaptive Tests (CAT) are quality of life measures developed specifically for use in children with cerebral palsy. This study examined the ability of the upper-extremity (UE) CP-PRO CAT to detect change in function after UE surgery compared with the Pediatric Outcomes Data Collection Instrument (PODCI), ABILHAND-Kids, and Box and Blocks test.

Methods: From 2009 to 2013, children with cerebral palsy who had UE musculoskeletal surgery completed the UE CP-PRO CAT, PODCI-UE, ABILHAND-Kids, and Box and Blocks tests before surgery (97 children) and at 3 postoperative intervals: 6 months (80 children), 12 months (73 children), and 24 months (52 children). Read More

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http://dx.doi.org/10.1016/j.jhsa.2018.12.007DOI Listing
February 2019
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Sex-Specific Genetic Susceptibility To Adverse Neurodevelopmental Outcome in Offspring of Pregnancies at Risk of Early Preterm Delivery.

Am J Perinatol 2019 Feb 7. Epub 2019 Feb 7.

Department of Obstetrics and Gynecology, University of Pittsburgh, Pittsburgh, Pennsylvania.

Objective:  To evaluate sex-specific genetic susceptibility to adverse neurodevelopmental outcome (ANO, defined as cerebral palsy [CP], mental, or psychomotor delay) at risk for early preterm birth (EPTB, < 32 weeks).

Study Design:  Secondary case-control analysis of a trial of magnesium sulfate (MgSO) before anticipated EPTB for CP prevention. Cases are infants who died by the age of 1 year or developed ANO. Read More

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http://dx.doi.org/10.1055/s-0039-1678535DOI Listing
February 2019
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Adults with cerebral palsy have higher prevalence of fracture compared to adults without cerebral palsy independent of osteoporosis and cardiometabolic diseases.

J Bone Miner Res 2019 Feb 7. Epub 2019 Feb 7.

Department of Physical Medicine and Rehabilitation, Michigan Medicine, University of Michigan, Ann Arbor, MI, USA.

Individuals with cerebral palsy (CP) have increased risk of fracture throughout their lifespan due to an underdeveloped musculoskeletal system, excess body fat, diminished mechanical loading, and early development of noncommunicable diseases. However, the epidemiology of fracture among adults with CP is unknown. The purpose of this cross-sectional study was to determine the prevalence of fracture among a large sample of privately-insured adults with CP, as compared to adults without CP. Read More

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http://dx.doi.org/10.1002/jbmr.3694DOI Listing
February 2019
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Application of a wearable switch to perform a mouse left click for a child with mix type of cerebral palsy: a single case study.

Disabil Rehabil Assist Technol 2019 Feb 7:1-6. Epub 2019 Feb 7.

a Department of Community Health Science, Graduate School of Health Science , Kobe University , Kobe , Japan.

Purpose: Children with cerebral palsy may face difficulties using handheld pointing devices, due to involuntary muscle movements. This study aimed at describing the idea of the new wearable sensor switch and assessing its feasibility as an access solution in a case of mixed-type cerebral palsy.

Methods: The study participant was a 17-year-old male with mixed-type cerebral palsy characterized by chorea-athetotic movements and bilateral spasticity with gross motor function classification system level V. Read More

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https://www.tandfonline.com/doi/full/10.1080/17483107.2018.1
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http://dx.doi.org/10.1080/17483107.2018.1520309DOI Listing
February 2019
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Sarcopenia among adults with cerebral palsy in South Korea.

PM R 2019 Feb 7. Epub 2019 Feb 7.

Department of Rehabilitation Medicine, Seoul National University College of Medicine, Seoul National University Boramae Medical Center, Seoul, Republic of Korea.

Background: Most adults with cerebral palsy (CP) encounter newly developing physical health problems and premature functional decline with aging. These physical and functional losses along with the characteristic symptoms of CP may heighten the risk of sarcopenia.

Objective: To determine the prevalence of sarcopenia among a selected group of adults with cerebral palsy and to identify the factors associated with the sarcopenia among them. Read More

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http://dx.doi.org/10.1002/pmrj.12134DOI Listing
February 2019
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Mortality due to cardiovascular disease, respiratory disease, and cancer in adults with cerebral palsy.

Dev Med Child Neurol 2019 Feb 6. Epub 2019 Feb 6.

Department of Medical Statistics, London School of Hygiene and Tropical Medicine, London, UK.

Aim: To compare mortality rates for cardiovascular disease, cancer, and respiratory disease between adults with cerebral palsy (CP) and the general population.

Method: A cohort study was conducted using data from adults with CP in England, identified through a primary care data set (the Clinical Practice Research Datalink), with linked data on death registrations from the Office for National Statistics. Cause of death was categorized according to International Classification of Diseases codes. Read More

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http://dx.doi.org/10.1111/dmcn.14176DOI Listing
February 2019
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