33,307 results match your criteria Cerebral Aneurysms


The Effect of Myosin Light Chain Kinase on the Occurrence and Development of Intracranial Aneurysm.

Front Cell Neurosci 2018 13;12:416. Epub 2018 Nov 13.

Department of Neurology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Myosin light chain kinase is a key enzyme in smooth muscle cell contraction. However, whether myosin light chain kinase plays a role in the occurrence or development of intracranial aneurysms is not clear. The present study explored the function of myosin light chain kinase in human intracranial aneurysm tissues. Read More

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http://dx.doi.org/10.3389/fncel.2018.00416DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6282066PMC
November 2018

Real-time Imaging of an Experimental Intracranial Aneurysm in Rats.

Neurol Med Chir (Tokyo) 2018 Dec 15. Epub 2018 Dec 15.

Department of Molecular Pharmacology, Research Institute, National Cerebral and Cardiovascular Center.

Subarachnoid hemorrhage due to rupture of a pre-existing intracranial aneurysm has quite a poor outcome in spite of intensive medical care. Hemodynamic stress loaded on intracranial arterial walls is considered as a trigger and a regulator of formation and progression of the disease, but how intracranial arterial walls or intracranial aneurysm walls behave under hemodynamic stress loading remains unclear. The purpose of this study was to visualize and analyze the wall motion of intracranial aneurysms to detect a pathological flow condition. Read More

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http://dx.doi.org/10.2176/nmc.oa.2018-0197DOI Listing
December 2018

Scalp nerves block for surgical clipping of cerebral aneurysms in patients allergic to nonsteroidal anti-inflammatory drugs.

J Clin Anesth 2018 Dec 12;54:156. Epub 2018 Dec 12.

Department of Anesthesiology, Showa University Hospital, Tokyo, Japan.

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http://dx.doi.org/10.1016/j.jclinane.2018.12.003DOI Listing
December 2018

Safety and efficacy of cangrelor in acute stenting for the treatment of cerebrovascular pathology: preliminary experience in a single-center pilot study.

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Lyerly Neurosurgery, Baptist Neurological Institute, Baptist Health, Jacksonville, Florida, USA.

Background: Treatment of acute cerebrovascular pathology, such as acute ischemic stroke or intracranial aneurysms, presents a challenge if an extracranial or intracranial stent is required; immediate platelet inhibition is vital. To date, there is no standardized approach for antiplatelet inhibition in an acute setting.

Objective: To report our preliminary experience and lessons learnt using cangrelor in acute neurointervention. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014396DOI Listing
December 2018

Pipeline shield with single antiplatelet therapy in aneurysmal subarachnoid haemorrhage: multicentre experience.

J Neurointerv Surg 2018 Dec 14. Epub 2018 Dec 14.

Institute of Neurological Sciences, Prince of Wales Hospital, Randwick, New South Wales, Australia.

Background: The Pipeline Embolisation Device with Shield technology (PED-Shield) is suggested to have reduced thrombogenicity. This reduced thrombogenicity may make it possible to use safely in the acute treatment of aneurysmal subarachnoid haemorrhage (aSAH) on single antiplatelet therapy (SAPT).

Objective: To evaluate the safety and efficacy of the off-label use of PED-Shield with SAPT for the acute treatment of aSAH. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014363DOI Listing
December 2018

Clipping of Basilar Perforator Pure Arterial Malformation Aneurysm: 2-Dimensional Operative Video.

Oper Neurosurg (Hagerstown) 2018 Dec 14. Epub 2018 Dec 14.

University of Miami, Department of Neurosurgery, Miami, Florida.

Pure arterial malformations are rarely-encountered intracranial lesions, often mistaken for arteriovenous malformations. A minority of these lesions may harbor associated aneurysms. In a recent series of 12 patients with pure arterial malformations, 3 patients had associated aneurysms. Read More

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http://dx.doi.org/10.1093/ons/opy382DOI Listing
December 2018

Efficiency and complications of Woven EndoBridge (WEB) devices for treatment of larger, complex intracranial aneurysms-a single-center experience.

Acta Neurochir (Wien) 2018 Dec 13. Epub 2018 Dec 13.

Institute of Clinical Medicine, University in Oslo, Problemveien 17, 0315, Oslo, Norway.

Background: Several recently published multicenter studies have reported high treatment feasibility, high safety, and good 6-month to 1-year efficiency when treating smaller intracranial aneurysms (IA) with WEB deployment. The purpose of the study was to evaluate the long-term efficiency and complications related to WEB treatment of larger, complex intracranial aneurysms in a small single-center cohort.

Methods: Patients with ruptured and unruptured IA were treated with WEB devices; data were collected prospectively and analyzed retrospectively. Read More

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http://link.springer.com/10.1007/s00701-018-3752-0
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http://dx.doi.org/10.1007/s00701-018-3752-0DOI Listing
December 2018
2 Reads

Endovascular management of ruptured distal posterior inferior cerebellar artery aneurysms: A retrospective cohort study.

Medicine (Baltimore) 2018 Dec;97(49):e13300

Department of Neurosurgery, Second Affiliated Hospital, School of Medicine.

Distal posterior inferior cerebellar artery (PICA) aneurysm is a kind of rare intracranial aneurysm with controversial evidence in managements. The main purposes of this research are to study the safety and effectiveness of parent artery occlusion (PAO) compared with selective aneurysm coiling (SAC) as well as figure out factors that affect the outcomes.All characteristics of patients that diagnosed with ruptured distal PICA aneurysm and treated with endovascular management in our hospital from July 2009 to February 2016 were retrospectively collected. Read More

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http://dx.doi.org/10.1097/MD.0000000000013300DOI Listing
December 2018

Perioperative Clinical Considerations in a Patient With Carotid Agenesis: A Case Report.

A A Pract 2018 Dec 11. Epub 2018 Dec 11.

From the Department of Anesthesiology, Northwestern Memorial Hospital, Chicago, Illinois.

An 86-year-old female with previously diagnosed congenitally absent right internal carotid artery presented for total shoulder arthroplasty. Bedside ultrasonography confirmed the anomaly and identified several arterial collateral vessels. No aberrant vessels were seen traversing the brachial plexus. Read More

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http://dx.doi.org/10.1213/XAA.0000000000000938DOI Listing
December 2018

Comparison of carotid and basilar bifurcation aneurysms versus non-T-angled bifurcations: the geometry is associated with the outcome.

Neurosurg Rev 2018 Dec 12. Epub 2018 Dec 12.

Department of Neurosurgery, Goethe-University Hospital, Schleusenweg 2-16, 60528, Frankfurt am Main, Germany.

Patients with ruptured aneurysms of carotid bifurcation artery seem to suffer less often from cerebral vasospasm and early brain injury and have a better clinical outcome. Aim of our study was to identify differences in clinical course and outcome in aneurysms of terminus segments (carotid bifurcation artery and basilar tip) compared to aneurysms of other aneurysm locations except carotid bifurcation artery and basilar tip. Patients with SAH were entered into a prospectively collected database (1999 to June 2014). Read More

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http://dx.doi.org/10.1007/s10143-018-01056-2DOI Listing
December 2018

Stents and Stent Mimickers in Endovascular Management of Wide-neck Intracranial Aneurysms.

Cureus 2018 Oct 5;10(10):e3420. Epub 2018 Oct 5.

Radiology, The Aga Khan University, Karachi, PAK.

Subarachnoid hemorrhage due to a ruptured cerebral aneurysm is a disastrous event accounting for approximately 5%-15% of all stroke cases and has a high mortality rate. One of the major goals in the management of these patients is to prevent rebleeding by securing the aneurysm either surgically or by endovascular means. Endovascular treatment is considered the first line of treatment for intracranial aneurysms; however, wide-neck aneurysms (WNAs) are specifically difficult to treat by endovascular means due to the difficulty in achieving a stable coil mass inside the aneurysm sac. Read More

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http://dx.doi.org/10.7759/cureus.3420DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6284878PMC
October 2018

The effect of intravascular interventional embolization and craniotomy on MMP-2, MMP-9 and caspase3 in serum of intracranial aneurysm patients.

Exp Ther Med 2018 Dec 14;16(6):4511-4518. Epub 2018 Sep 14.

Department of Neurosurgery, Hulunbeier People's Hospital, Hulunbuir, Inner Mongolia 021000, P.R. China.

The effect of intravascular interventional embolization and surgical operation on matrix metalloprotein (MMP)-2, MMP-9 and caspase3 in serum of intracranial aneurysms was analyzed to study the mechanisms. Seventy-nine patients of intracranial aneurysms from September 2011 to August 2014 were divided into the intervention group (n=41) and the craniotomy group (n=38) based on treatment methods, and 40 cases of normal volunteers with normal physical examination were selected as the control group. Patients in the intervention group were treated with intravascular interventional embolization, and the surgical group was treated with craniotomy and no treatment was performed in the control group. Read More

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http://dx.doi.org/10.3892/etm.2018.6740DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6257825PMC
December 2018

Orofacial neuralgia associated with a middle cerebral artery aneurysm.

Aust Dent J 2018 Dec 7. Epub 2018 Dec 7.

Senior Lecturer, School of Dentistry, University of Adelaide, South Australia, Australia.

Chronic orofacial pain of neuropathic origin can present diagnostic and management dilemmas to dental practitioners and also affect the patient's quality of life. Intracranial aneurysms are a potential cause of stroke, with associated sub-arachnoid haemorrhage leading to high rates of mortality and morbidity. A patient who had been previously managed for symptoms of temporomandibular joint disorder (TMD) presented with sharp, shooting pain of moderate intensity. Read More

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http://dx.doi.org/10.1111/adj.12668DOI Listing
December 2018
1 Read

Y-Stent-Assisted Coiling of Wide-Neck Bifurcation Intracranial Aneurysms: A Meta-Analysis.

AJNR Am J Neuroradiol 2018 Dec 6. Epub 2018 Dec 6.

From the Interventional Neuroradiology Unit (F.C., N.L., S.N., L.R., A.R., A.L., S.M.), Careggi University Hospital, Florence, Italy.

Background: Y-stent-assisted coiling for wide-neck intracranial aneurysms required further investigation.

Purpose: Our aim was to analyze outcomes after Y-stent placement in wide-neck aneurysms.

Data Sources: We performed a systematic search of 3 data bases for studies published from 2000 to 2018. Read More

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http://www.ajnr.org/lookup/doi/10.3174/ajnr.A5900
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http://dx.doi.org/10.3174/ajnr.A5900DOI Listing
December 2018
3 Reads

Angiographic Features of Intracranial Aneurysms in Ecuador.

J Stroke Cerebrovasc Dis 2018 Dec 3. Epub 2018 Dec 3.

University of Iowa School of Medicine, Universidad San Francisco de Quito, Quito, Ecuador, USA.

Background: Most of the literature describing morphological features of intracranial aneurysms (IAs) is from North-America, East-Asia, and Europe. There is limited data from South-America. We describe the epidemiologic and angiographic features of ruptured and unruptured IAs in a cohort of patients from Ecuador. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.11.020DOI Listing
December 2018

Comparison of PED and FRED Flow Diverters for Internal Carotid Artery Aneurysms: A Propensity Score-Matched Cohort Study.

Neurosurgery 2018 Dec 12. Epub 2018 Dec 12.

Department of Neurology, Paracelsus Medical University, Salzburg, Austria.

Background: Flow diversion has become an accepted endovascular treatment modality for intracranial aneurysms. Studies comparing different types of flow diverters are currently lacking.

Objective: To perform a propensity score-matched cohort study comparing the Pipeline Embolization Device (PED; Medtronic, Dublin, Ireland) and Flow Redirection Endoluminal Device (FRED; MicroVention, Aliso Viejo, California). Read More

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https://academic.oup.com/neurosurgery/advance-article/doi/10
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http://dx.doi.org/10.1093/neuros/nyy572DOI Listing
December 2018
2 Reads

Postoperative antiplatelet therapy in the treatment of complex basilar apex aneurysms implementing Hunterian ligation and extracranial-to-intracranial bypass: review of the literature with an illustrative case report.

World Neurosurg 2018 Dec 8. Epub 2018 Dec 8.

Neurorestoration Center, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA; Department of Neurological Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA. Electronic address:

Large, broad-based basilar artery (BA) apex aneurysms involving multiple arterial origins are complex lesions commonly not amenable to direct clipping or endovascular management. BA proximal (Hunterian) occlusion with extracranial-to-intracranial bypass is a supported strategy if one or both posterior communicating arteries are small. Hunterian ligation risks sudden aneurysm thrombosis and thromboembolism in the perforator rich BA apex. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.237DOI Listing
December 2018

Predictors of cognitive function in the acute phase after aneurysmal subarachnoid hemorrhage.

Acta Neurochir (Wien) 2018 Dec 8. Epub 2018 Dec 8.

Department of Neurosurgery, Oslo University Hospital, Rikshospitalet, P.B. 4950, Nydalen, 0424, Oslo, Norway.

Background: Cognitive dysfunction is the most common form of neurological impairment after aneurysmal subarachnoid hemorrhage (aSAH) in the chronic phase. Cognitive deficits in the acute phase after aSAH, however, remain scarcely investigated. The aim of the present study was to test cognitive function and to identify medical predictors of cognitive deficits in the acute phase of aSAH. Read More

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http://link.springer.com/10.1007/s00701-018-3760-0
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http://dx.doi.org/10.1007/s00701-018-3760-0DOI Listing
December 2018
2 Reads

Early Intracranial Aneurysm Recurrence after Microsurgical Clip Ligation: Case Report and Review of the Literature.

J Neurol Surg Rep 2018 Oct 7;79(4):e93-e97. Epub 2018 Dec 7.

Department of Neurosurgery, Kantonsspital Aarau (KSA), Aarau, Switzerland.

Microsurgical clip ligation is considered a definitive treatment for intracranial aneurysms (IAs), resulting in low rates of local recurrence that range from 0.2 to 0.5% and a latency period that averages about a decade. Read More

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http://dx.doi.org/10.1055/s-0038-1676454DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6286179PMC
October 2018

Delayed diagnosis of post-traumatic aneurysm of distal anterior cerebral artery.

Surg Neurol Int 2018 1;9:222. Epub 2018 Nov 1.

Department of Neurosurgery, Regina Elena National Cancer Institute, Neurosurgery Department, Via Elio Chianesi 53, 00144, Rome, Italy.

Background: Traumatic intracranial aneurysms (TICA) are often associated with poor prognosis and should be diagnosed as soon as possible to prevent delayed intracranial hemorrhage and high rates of morbidity/mortality related to bleeding. Diagnosis requires a high index of suspicion. The goal of treatment is to exclude the aneurysm issue with surgical or endovascular methods. Read More

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http://dx.doi.org/10.4103/sni.sni_252_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6238328PMC
November 2018

Blood Culture-Negative but Clinically Diagnosed Infective Endocarditis Complicated by Intracranial Mycotic Aneurysm, Brain Abscess, and Posterior Tibial Artery Pseudoaneurysm.

Case Rep Neurol Med 2018 8;2018:1236502. Epub 2018 Nov 8.

Department of Anesthesiology/Critical Care Medicine, Johns Hopkins University, School of Medicine, Baltimore, MD, USA.

Blood culture-negative endocarditis is often severe and difficult to diagnose. It is necessary to emphasize the importance for the early diagnosis and accurate treatment of blood culture-negative endocarditis. Here, we described the relevant clinical information of a blood culture-negative but clinically diagnosed infective endocarditis complicated by intracranial mycotic aneurysm, brain abscess, and posterior tibial artery pseudoaneurysm. Read More

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http://dx.doi.org/10.1155/2018/1236502DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6250033PMC
November 2018

[Results of a single-centre study of open and endovascular operations of prosthetic repair of abdominal aortic aneurysms].

Angiol Sosud Khir 2018 ;24(4):126-130

National Medical Research Centre named after V.A. Almazov under the RF Ministry of Public Health, Saint Petersburg, Russia.

Objective: The purpose of the study was to assess surgical outcomes in patients suffering from an infrarenal abdominal aortic aneurysm and treated at the Department of Cardiovascular Surgery #2 of the National Medical Research Centre named after V.A. Almazov. Read More

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January 2018

Parent Artery Occlusion for Unruptured Cerebral Aneurysms: Results of the Japanese Registry of Neuroendovascular Therapy 3.

Neurol Med Chir (Tokyo) 2018 Dec 7. Epub 2018 Dec 7.

Department of Neuroendovascular Therapy, Institute of Biomedical Research and Innovation.

Although the current standard treatment for unruptured aneurysms comprises surgical clipping or endovascular coiling, these techniques are not suitable for some cases, such as large, giant, and fusiform aneurysms. Endovascular parent artery occlusion (PAO), which includes internal trapping and proximal occlusion, is a well-established alternative treatment for such cases. Here, we retrospectively reviewed PAO cases from the Japanese Registry of Neuroendovascular Therapy 3, a nation-wide survey of all neuroendovascular therapy cases between 2010 and 2014. Read More

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http://dx.doi.org/10.2176/nmc.st.2018-0190DOI Listing
December 2018

Construction of aneurysmal models on a curved vascular segment of a carotid siphon model for testing endovascular devices.

World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, The First Hospital, Hebei Medical University, Shijiazhuang, Hebei Province, China 050030.

Purpose: To investigate construction of an aneurysm on a curved vascular segment of a carotid siphon model for testing endovascular devices.

Materials And Methods: Pre-shaped carotid siphon models of polytetrafluoroethylene were constructed from a human cadaver for confining canine common carotid artery (CCA). The canine right external jugular vein was isolated and harvested to make a venous pouch by suturing one end. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.224DOI Listing
December 2018

Pipeline embolization of a giant cavernous ICA aneurysm with direct carotid puncture and arteriotomy closure device: neuroendovascular surgical video.

World Neurosurg 2018 Dec 6. Epub 2018 Dec 6.

Department of Neurosurgery, University of Illinois at Chicago, Chicago, Illinois, 60612. Electronic address:

Flow diversion technology has revolutionized the treatment of complex anterior circulation cerebral aneurysms. However, vessel tortuosity and atherosclerotic disease may hamper the standard transfemoral access used in these procedures. Percutaneous direct carotid puncture is a viable alternative, but adequate carotid closure must be achieved. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.230DOI Listing
December 2018

Post-thrombolysis rupture of small lenticulostriate aneurysms: A report of 2 consecutive cases.

J Clin Neurosci 2018 Oct 24. Epub 2018 Oct 24.

Department of Neurology, National Neuroscience Institute, Singapore.

The 2018 American Heart Association/American Stroke Association (AHA/ASA) guidelines stated that the administration of intravenous recombinant tissue-type plasminogen activator (rTPA) for acute ischaemic stroke is probably safe for patients with small (i.e. <10 mm) unruptured intracranial aneurysms. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.10.087DOI Listing
October 2018

MRI Presentation of Infectious Intracranial Aneurysms in Infective Endocarditis.

Neurocrit Care 2018 Dec 5. Epub 2018 Dec 5.

Cerebrovascular Center, Neurological Institute, Cleveland Clinic, Cleveland, OH, USA.

Background: The radiographic appearance of infectious intracranial aneurysms (IIAs) of infective endocarditis (IE) on magnetic resonance imaging (MRI) of brain is varied. We aimed to describe the IIA-specific MRI features in a series of patients with IIAs.

Methods: Records of patients with active IE who had digital subtraction angiography (DSA) at a tertiary medical center from January 2011 to December 2016 were reviewed. Read More

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http://link.springer.com/10.1007/s12028-018-0654-1
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http://dx.doi.org/10.1007/s12028-018-0654-1DOI Listing
December 2018
5 Reads

Preliminary Clinical Microneurosurgical Experience With the 4K3-Dimensional Microvideoscope (ORBEYE) System for Microneurological Surgery: Observation Study.

Oper Neurosurg (Hagerstown) 2018 Dec 3. Epub 2018 Dec 3.

Department of Neurological Surgery, Nippon Medical School, Tokyo, Japan.

Background: The exoscope has been reported as a novel neurosurgical instrumentation in clinical practice.

Objective: To investigate the possibility that ORBEYE (OE), a novel instrument that excludes eyepiece lenses and allows for microsurgery by observation of the 4K3D monitor, could replace microscopes.

Methods: We report 22 clinical cases by 5 experienced neurosurgeons and the comparative results of training 10 residents. Read More

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http://dx.doi.org/10.1093/ons/opy277DOI Listing
December 2018
1 Read

The use of flow diverters to treat small (≤5 mm) ruptured, saccular aneurysms.

Surg Neurol Int 2018 30;9:216. Epub 2018 Oct 30.

Neuroradiological Clinic, Neurocenter, Leipzig, Germany.

Background: There is limited published literature on the use of flow diverting stents (FDS) to treat ruptured intracranial aneurysms in the acute stage. We present our experience of using FDS to treat small (≤5 mm) ruptured aneurysms.

Methods: We retrospectively identified all patients with ≤5 mm ruptured aneurysms treated exclusively with FDS between February 2009 and February 2016. Read More

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http://dx.doi.org/10.4103/sni.sni_243_18DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6219287PMC
October 2018
1 Read

Surgery for very large and giant intracranial aneurysms: Results and complications.

Neurol India 2018 Nov-Dec;66(6):1741-1757

Department of Neurosurgery, University of Washington, Seattle, Washington, USA.

Background: Results of and the complications encountered during surgery for very large and giant intracranial aneurysms are illustrated.

Objective: To analyze a consecutive series of patients with very large and giant aneurysms treated with microsurgery.

Methods: This retrospective study included seventy six very large and giant aneurysms which were managed by clipping and bypass technique. Read More

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http://dx.doi.org/10.4103/0028-3886.246291DOI Listing
December 2018
1 Read

Patency of anterior choroidal artery after flow diverter deployment with assessment of magnetic resonance imaging follow-up.

Neuroradiol J 2018 Dec 3:1971400918817149. Epub 2018 Dec 3.

2 Department of Neurosurgery, Juntendo University School of Medicine, Japan.

Purpose: We aimed to analyse the patency rate of the anterior choroidal artery, and presented imaging and neurological findings, after deployment of a flow diverter in the anterior choroidal artery in the treatment of patients with intracranial aneurysms.

Methods: Among the 139 patients who underwent a flow diverter deployment from December 2012 to September 2017 in our hospital, there were 21 patients (15.1%) for whom their anterior choroidal artery was covered for the procedure with a flow diverter. Read More

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http://dx.doi.org/10.1177/1971400918817149DOI Listing
December 2018
1 Read

Management of patients with unruptured intracranial aneurysms.

Curr Opin Neurol 2019 Feb;32(1):49-53

Department of Neurology and Neurosurgery, Brain Center Rudolf Magnus, University Medical Center Utrecht, Utrecht, The Netherlands.

Purpose Of Review: Intracranial aneurysms are frequent incidental findings on cranial imaging. The decision for preventive treatment depends on the presumed risk of rupture, the efficacy and risk of complications of preventive treatment, and the quality of life having to live with an unruptured aneurysms. Data on all these factors are still incomplete, and additional data are needed. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000642DOI Listing
February 2019
3 Reads

Is surgical parent artery occlusion effective for intracranial aneurysms measuring over 10 mm in size? Result from long-term follow-up of size changes and outcomes.

Acta Neurochir (Wien) 2018 Dec 4. Epub 2018 Dec 4.

Department of Neurosurgery, Showa University School of Medicine, 5-8 Hatanodai 1-chome, Shinagawa-ku, Tokyo, 142-8666, Japan.

Background: There have been no long-term follow-up reports pertaining to chronological size changes in large or giant unruptured intracranial aneurysms treated with surgical parent artery occlusion (PAO). The object of this study is to investigate the utility and safety of surgical PAO by conducting a long-term follow-up of chronological aneurysm size changes and outcomes.

Methods: A retrospective study of 21 unruptured intracranial aneurysms measuring over 10 mm (20 patients) treated with surgical PAO in the period 2012-2017 was conducted. Read More

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http://dx.doi.org/10.1007/s00701-018-3756-9DOI Listing
December 2018
1 Read

Delayed parent artery occlusions following use of SILK flow diverters for treatment of intracranial aneurysms.

J Neurointerv Surg 2018 Dec 4. Epub 2018 Dec 4.

Department of Radiology, Dalhousie University, Halifax and University of Manitoba, Winnipeg, Canada.

Background: The efficacy of SILK flow diverters (SFD) in the management of cerebral aneurysms has been established. However, the risk of complications with parent artery occlusion (PAO) remains to be fully elucidated. The purpose of our study was to analyze intracranial aneurysms treated with SFDs and assess for occurrences and potential risk factors for PAO. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014354DOI Listing
December 2018
1 Read

Confidence of treatment decision and perceived risk of procedure-related neurological complications in the management of unruptured intracranial aneurysms.

J Neurointerv Surg 2018 Dec 4. Epub 2018 Dec 4.

Centre for Radiology and Endoscopy, Department of Diagnostic and Interventional Neuroradiology, University Medical Centre Hamburg-Eppendorf, Hamburg, Germany.

Background And Purpose: To evaluate factors influencing the confidence of management recommendation for unruptured intracranial aneurysms (UIAs) and to assess the ability of neurointerventionalists to predict procedure-related neurological complications compared with a 3-point risk score.

Materials And Methods: Twenty-eight neurointerventionalists were asked to evaluate digital subtraction angiographies examinations of patients with UIAs by determining the best management approach, their level of confidence in their management recommendation, and estimating the risk of procedure-related neurological complications. Knowledge and experience in interventional neuroradiology (INR) of each participant were assessed. Read More

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http://dx.doi.org/10.1136/neurintsurg-2018-014346DOI Listing
December 2018
1 Read

Size, Aspect Ratio and Anatomic Location of Ruptured Intracranial Aneurysms: Consecutive Series of 415 Patients from a Prospective, Multicenter, Observational Study.

Cell Transplant 2018 Dec 4:963689718817227. Epub 2018 Dec 4.

1 Department of Neurosurgery, Huashan Hospital, Shanghai Medical College, Fudan University, Shanghai, China.

To analyze the size and location distribution of ruptured intracranial aneurysms (IAs) helps to provide evidence for clinical treatment of unruptured IAs using this feature of aneurysms. In this study, 415 patients who presented with an acute subarachnoid hemorrhage caused by IAs were enrolled from eight tertiary referral centers between June 2016 and March 2018. The size, aspect ratio and anatomic location of ruptured IAs were defined and reported by patient sex. Read More

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http://dx.doi.org/10.1177/0963689718817227DOI Listing
December 2018
1 Read

Endoscopic endonasal clipping of cerebral aneurysms: started from the bottom, now we here!

J Neurosurg Sci 2018 Dec 5. Epub 2018 Dec 5.

Department of Neurosurgery, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India.

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https://www.minervamedica.it/index2.php?show=R38Y9999N00A181
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http://dx.doi.org/10.23736/S0390-5616.18.04627-1DOI Listing
December 2018
2 Reads
0.780 Impact Factor

Convolutional Neural Networks for the Detection and Measurement of Cerebral Aneurysms on Magnetic Resonance Angiography.

J Digit Imaging 2018 Dec 3. Epub 2018 Dec 3.

Radiology, Columbia University Medical Center, 622 West 168th Street, PB 1-301, New York, NY, USA.

Aneurysm size correlates with rupture risk and is important for treatment planning. User annotation of aneurysm size is slow and tedious, particularly for large data sets. Geometric shortcuts to compute size have been shown to be inaccurate, particularly for nonstandard aneurysm geometries. Read More

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http://dx.doi.org/10.1007/s10278-018-0162-zDOI Listing
December 2018
2 Reads

A case report on middle cerebral artery aneurysm treated by rapid ventricular pacing: A CARE compliant case report.

Authors:
Yi Ping Huahua Gu

Medicine (Baltimore) 2018 Nov;97(48):e13320

Department of Anesthesiology, Huashan Hospital Fudan University, Shanghai, China.

Rationale: Cerebral aneurysm is a common cause of intracranial hemorrhage, stroke, and death. It is treated with vascular surgeries, such as coil embolism and artery clipping. However, surgery itself is a risk factor that may cause rupture of aneurysm, and leads to irreversible brain damage, and even death. Read More

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http://dx.doi.org/10.1097/MD.0000000000013320DOI Listing
November 2018
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Endovascular Treatment for Ruptured Aneurysms at Distal Cerebral Arteries.

World Neurosurg 2018 Nov 27. Epub 2018 Nov 27.

Department of Neurosurgery The Tenth Affiliated People's Hospital of Shanghai Tong Ji University No. 301, Middle Yan Chang Road; Shanghai, 200072, China. Electronic address:

Purpose: To evaluate the feasibility and efficacy of the endovascular treatment for ruptured aneurysms at distal cerebral arteries.

Methods: A total of 30 ruptured aneurysms at distal cerebral arteries in 30 patients received endovascular treatment (EVT). Distal cerebral arteries were defined as arteries distal to the A2 or M2 segmentations in the anterior circulation and P2 segmentation in the posterior circulation or at other small branches or perforating arteries. Read More

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http://dx.doi.org/10.1016/j.wneu.2018.11.178DOI Listing
November 2018
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Vascular Behçet's syndrome: an update.

Intern Emerg Med 2018 Nov 29. Epub 2018 Nov 29.

Department of Experimental and Clinical Medicine, University of Firenze, Firenze, Italy.

Behçet's syndrome (BS) is a complex vasculitis, characterised by peculiar histological, pathogenetic and clinical features. Superficial venous thrombosis (SVT) and deep vein thrombosis (DVT) are the most frequent vascular involvements, affecting altogether 15-40% of BS patients. Atypical thrombosis is also an important clinical feature of BS, involving the vascular districts of the inferior and superior vena cava, suprahepatic veins with Budd-Chiari syndrome, portal vein, cerebral sinuses and right ventricle. Read More

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http://dx.doi.org/10.1007/s11739-018-1991-yDOI Listing
November 2018
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Therapeutic evaluation of a patient with ruptured intracranial aneurysm without subarachnoid hemorrhage by CT imaging: a case report.

BMC Neurol 2018 Nov 29;18(1):197. Epub 2018 Nov 29.

China-Japan Union Hospital of Jilin University, Jilin, China.

Background: The majority of ruptured intracranial aneurysms are combined with subarachnoid hemorrhage, but patients with only intracerebral hematoma without any subarachnoid hemorrhage are extremely rare.

Case Presentation: The patient was hospitalized due to sudden dizziness combined with slurred speech. The patient showed considerable decreased physical activity without any nuchal rigidity. Read More

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http://dx.doi.org/10.1186/s12883-018-1197-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6263545PMC
November 2018
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Inflammatory Smooth Muscle Cells Induce Endothelial Cell Alterations to Influence Cerebral Aneurysm Progression via Regulation of Integrin and VEGF Expression.

Cell Transplant 2018 Nov 30:963689718815824. Epub 2018 Nov 30.

1 Department of Neurosurgery, Huashan Hospital of Fudan University. Shanghai, China.

Cerebral aneurysm growth is characterized by vessel wall frailness, although the underlying cellular mechanisms are unclear. Here, we examined the relationship between inflammatory smooth muscle cells (SMCs) and endothelial cells (ECs) in cerebral aneurysms, including the mechanisms underlying inflammatory SMC-induced changes in ECs. Five saccular cerebral aneurysms were collected and five temporal artery samples were used as controls. Read More

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http://dx.doi.org/10.1177/0963689718815824DOI Listing
November 2018

Nationwide analysis of hospital-to-hospital transfer in patients with aneurysmal subarachnoid hemorrhage requiring aneurysm repair.

Authors:

J Neurosurg 2018 Oct 1:1-8. Epub 2018 Oct 1.

OBJECTIVEAneurysmal subarachnoid hemorrhage (aSAH) has devastating consequences. The association between higher institutional volumes and improved outcomes for aSAH patients has been studied extensively. However, the literature exploring patterns of transfer in this context is sparse. Read More

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http://dx.doi.org/10.3171/2018.4.JNS172269DOI Listing
October 2018
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Ruptured intracranial aneurysm in a patient with autosomal recessive polycystic kidney disease.

Authors:

J Neurosurg Pediatr 2018 Oct 1:1-5. Epub 2018 Oct 1.

Aneurysmal rupture can result in devastating neurological consequences and can be complicated by comorbid disease processes. Patients with autosomal recessive polycystic kidney disease (ARPKD) have a low rate of reported aneurysms, but this may be due to the relative high rate of end-stage illnesses early in childhood. Authors here report the case of a 10-year-old boy with ARPKD who presented with a Hunt and Hess grade V subarachnoid hemorrhage requiring emergency ventriculostomy, embolization, and decompressive craniectomy. Read More

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http://dx.doi.org/10.3171/2018.8.PEDS18286DOI Listing
October 2018
4 Reads

Cerebral revascularization for the management of complex intracranial aneurysms: a single-center experience.

Authors:

J Neurosurg 2018 Oct 1:1-11. Epub 2018 Oct 1.

OBJECTIVEBecause simple intracranial aneurysms (IAs) are increasingly treated endovascularly, neurovascular surgery has become focused on complex IAs that may require deconstructive aneurysm therapy with concomitant surgical bypass. The authors describe the decision-making process concerning cerebral revascularization and present outcomes that were achieved in a large case series of complex IAs managed with cerebral revascularization and parent artery occlusion.METHODSThe authors retrospectively reviewed the medical records, including neuroimaging studies, operative reports, and follow-up clinic notes, of all patients who were treated at the National Brain Aneurysm Center between July 1997 and June 2015 using cerebral revascularization as part of the management of an IA. Read More

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http://dx.doi.org/10.3171/2018.4.JNS172752DOI Listing
October 2018
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Software-based simulation for preprocedural assessment of braided stent sizing: a validation study.

Authors:

J Neurosurg 2018 Nov 1:1-7. Epub 2018 Nov 1.

OBJECTIVEThe authors sought to validate the use of a software-based simulation for preassessment of braided self-expanding stents in the treatment of wide-necked intracranial aneurysms.METHODSThis was a retrospective, observational, single-center study of 13 unruptured and ruptured intracranial aneurysms treated with braided self-expanding stents. Pre- and postprocedural angiographic studies were analyzed. Read More

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http://dx.doi.org/10.3171/2018.5.JNS18976DOI Listing
November 2018

Management of recurrent intracranial aneurysms after coil embolization: a novel classification scheme based on angiography.

Authors:

J Neurosurg 2018 Nov 1:1-7. Epub 2018 Nov 1.

OBJECTIVERecurrent aneurysms after coil embolization remain a challenging issue. The goal of the present study was to report the authors' experience with recurrent aneurysms after coil embolization and to discuss the radiographic classification scheme and recommended management strategy.METHODSAneurysm treatments from a single institution over a 6-year period were retrospectively reviewed. Read More

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http://dx.doi.org/10.3171/2018.6.JNS181046DOI Listing
November 2018
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Whole blood aggregometry prior to Pipeline embolization device treatment of intracranial aneurysms: defining an optimal platelet inhibition cutoff value for clopidogrel.

Authors:

J Neurosurg 2018 Nov 1:1-8. Epub 2018 Nov 1.

OBJECTIVEDual antiplatelet therapy is required for the treatment of intracranial aneurysms with the Pipeline embolization device (PED). Platelet function testing (PFT) is often used to assess the efficacy of the antiplatelet regimen prior to PED placement. The optimal impedance values for whole blood aggregometry in this setting have not been defined. Read More

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http://dx.doi.org/10.3171/2018.6.JNS181044DOI Listing
November 2018
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