1,703 results match your criteria Central Vertigo


Peripheral vestibular disorders: an update.

Curr Opin Neurol 2019 Feb;32(1):165-173

Otology & Neurotology Group CTS495, Department of Genomic Medicine- Centro de Genómica e Investigación Oncológica - Pfizer/Universidad de Granada/ Junta de Andalucía (Genyo), PTS.

Purpose Of Review: To provide an update on the most frequent peripheral vestibular disorders.

Recent Findings: The on-going classification of vestibular disorders by the Bárány Society represents major progress. The diagnosis of bilateral vestibulopathy (BVP) requires quantitative testing of vestibular function. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000649DOI Listing
February 2019

What Is Behind Cerebellar Vertigo and Dizziness?

Cerebellum 2018 Dec 14. Epub 2018 Dec 14.

Department of Neurology, Ludwig-Maximilians University, Marchioninistrasse 15, 81377, Munich, Germany.

The differential diagnosis of vertigo or dizziness as a result of cerebellar disorders can be difficult as many patients with a cerebellar pathology do not present with the full spectrum of cerebellar signs. The main goal of this study was to describe the typical clinical features of these patients with vertigo or dizziness of a cerebellar origin. We reviewed the medical records of 5400 patients with vertigo and dizziness from our tertiary outpatient clinic for vertigo and balance disorders. Read More

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http://dx.doi.org/10.1007/s12311-018-0992-8DOI Listing
December 2018

[Analysis of nystagmus and medical history of 121 patients positive with positional test].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Oct;32(19):1491-1494

Department of Otolaryngology, Kuang Tien General Hospital, Taichung, Taiwan.

To observe the characteristics of positional nystagmus and clinical profile of patients with positive positional test, and to explore its possible pathogenesis. One hundred and twenty-one patients with positive positional test in the vestibular function examination were enrolled in the Peking University International Hospital from January to June in 2017. According to the 2017 BPPV guidelines, patients with test positive positional nystagmus were divided into two groups: definite BPPV and the controversial syndrome. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.19.012DOI Listing
October 2018

[Characteristics analysis of patients with benign paroxysmal positional vertigo-spontaneously cured].

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Sep;32(18):1426-1428

Department of Otolaryngology Head and Neck Surgery, Dalian Municipal Central Hospital Affiliated of Dalian Medical University.

To analyze the characteristics of patients with benign paroxysmal positional vertigo which were spontaneously cured. A total of 1 257 patients with chief complaint of positional vertigo were included and analyzed retrospectively, in which 921 cases were diagnosed as BPPV with the diagnosis standard of Guiyang meeting, and the other 336 cases were negative in the positional test diagnosed as BPPV-spontaneously cured. The age,gender and history course of the two groups were analyzed respectively. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.18.015DOI Listing
September 2018
1 Read

[Approach to patients with vertigo].

Medicina (B Aires) 2018 ;78(6):410-416

Servicio de Otorrinolaringología, Hospital Británico de Buenos Aires, Argentina.

Vertigo is defined as an abnormal sensation of body motion or of its surrounding objects. It is a common chief complaint in emergency departments comprising 2 to 3% of these consultations worldwide. Vertigo is classified as peripheral or central, according to its origin, and can also be occasionally mixed, the most common cause of peripheral involvement being benign paroxysmal positional vertigo. Read More

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January 2018
6 Reads

Baclofen for alcohol use disorder.

Cochrane Database Syst Rev 2018 Nov 26;11:CD012557. Epub 2018 Nov 26.

Department of Epidemiology, Lazio Regional Health Service, Via Cristoforo Colombo, 112, Rome, Italy, 00154.

Background: Alcohol use disorder (AUD) and alcohol-related impairments belong to the most widespread psychiatric disorders leading to specific psychophysical, affective and cognitive symptoms and consequences for psychosocial well-being and health. Alcohol consumption is increasingly becoming a problem in many developing regions and AUD prevalence is estimated at 4.1% worldwide, with highest prevalence in European countries (7. Read More

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http://dx.doi.org/10.1002/14651858.CD012557.pub2DOI Listing
November 2018
1 Read

Clinical presentation, risk factors and outcome of central nervous system metastasis vs stroke in cancer patients.

Curr Probl Cancer 2018 Nov 16. Epub 2018 Nov 16.

Neuro-oncology Unit, Research Unit, Instituto Nacional de Cancerología, Mexico City, Mexico.

Background And Purpose: Cancer and stroke are the second and third causes of death worldwide; brain metastases (BM) occur in one third of patients with cancer, any neurologic deficit in these population always prompts the clinician to discard metastases for their presence carries a bad outcome. Both might share clinical presentation and differences in their outcome are not entirely known. The aim was to compare risk factors, clinical presentation, and outcome of cancer patients with BM vs stroke. Read More

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http://dx.doi.org/10.1016/j.currproblcancer.2018.09.001DOI Listing
November 2018
2 Reads

Vestibular dysfunction and concussion.

Handb Clin Neurol 2018 ;158:135-144

Baylor Institute for Rehabilitation, Frisco, TX, United States.

The assessment and treatment of sport-related concussion (SRC) often requires a multifaceted approach. Vestibular dysfunction represents an important profile of symptoms and pathology following SRC, with high prevalence and association with prolonged recovery. Signs and symptoms of vestibular dysfunction may include dizziness, vertigo, disequilibrium, nausea, and visual impairment. Read More

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https://linkinghub.elsevier.com/retrieve/pii/B97804446395470
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http://dx.doi.org/10.1016/B978-0-444-63954-7.00014-8DOI Listing
January 2018
13 Reads

Disorders of the inner-ear balance organs and their pathways.

Handb Clin Neurol 2018 ;159:385-401

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia; Neurology Department, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia. Electronic address:

Disorders of the inner-ear balance organs can be grouped by their manner of presentation into acute, episodic, or chronic vestibular syndromes. A sudden unilateral vestibular injury produces severe vertigo, nausea, and imbalance lasting days, known as the acute vestibular syndrome (AVS). A bedside head impulse and oculomotor examination helps separate vestibular neuritis, the more common and innocuous cause of AVS, from stroke. Read More

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https://linkinghub.elsevier.com/retrieve/pii/B97804446391650
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http://dx.doi.org/10.1016/B978-0-444-63916-5.00025-2DOI Listing
January 2018
3 Reads

Vestibular rehabilitation: advances in peripheral and central vestibular disorders.

Curr Opin Neurol 2019 Feb;32(1):137-144

Department of Physical Therapy, University of Pittsburgh, Pittsburgh, Pennsylvania.

Purpose Of Review: Rehabilitation for persons with vertigo and balance disorders is becoming commonplace and the literature is expanding rapidly. The present review highlights recent findings of both peripheral and central vestibular disorders and provides insight into evidence related to new rehabilitative interventions. Risk factors will be reviewed to create a better understanding of patient and clinical characteristics that may effect recovery among persons with vestibular disorders. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000632DOI Listing
February 2019
16 Reads

Thalamocortical network: a core structure for integrative multimodal vestibular functions.

Curr Opin Neurol 2019 Feb;32(1):154-164

German Center for Vertigo and Balance Disorders.

Purpose Of Review: To apply the concept of nonreflexive sensorimotor and cognitive vestibular functions and disturbances to the current view of separate right and left thalamocortical systems.

Recent Findings: The neuronal modules for sensorimotor and cognitive functions are organized in so-called provincial hubs with intracommunity connections that interact task-dependently via connector hubs. Thalamic subnuclei may serve not only as provincial hubs but also in higher order nuclei as connector hubs. Read More

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http://dx.doi.org/10.1097/WCO.0000000000000638DOI Listing
February 2019
7 Reads

The Hippocratic Doctrine of "the Acute Brain Suffering" as the Brain Stroke.

J Stroke Cerebrovasc Dis 2018 Nov 9. Epub 2018 Nov 9.

History of Medicine, School of Medicine, University of Crete, Heraklion, Greece. Electronic address:

Background: The ancient Greek term "apoplexy" as is repeatedly mentioned by the Hippocratic School of Medicine, included a cluster of diseases, mainly those concerning the central nervous system. The term was wrongfully infiltrated in Western European medicine as synonymous to what is called today a "stroke" of the brain.

Objective: While in "Corpus Hippocraticum" the definition of the stroke was rather ambiguous; our study aims to unveil those fragments referring to it, in order to compose the Hippocratic theory of what it stood for "Acute Brain Suffering" (Greek: Οξείες Οδύνες του Εγκεφάλου) during the Classical era of ancient Greece. Read More

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http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2018.10.017DOI Listing
November 2018

Histamine H1 receptor contributes to vestibular compensation.

J Neurosci 2018 Nov 9. Epub 2018 Nov 9.

State Key Laboratory of Pharmaceutical Biotechnology and Department of Physiology, School of Life Sciences, Nanjing University, 163 Xianlin Avenue, Nanjing 210023, China

Vestibular compensation is responsible for the spontaneous recovery of postural, locomotor and oculomotor dysfunctions in patients with peripheral vestibular lesion or posterior circulation stroke. Mechanism investigation of vestibular compensation is of great importance in both facilitating recovery of vestibular function and understanding the post-lesion functional plasticity in the adult central nervous system. Here, we report that postsynaptic histamine H1 receptor contributes greatly to facilitating vestibular compensation. Read More

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http://www.jneurosci.org/content/early/2018/11/09/JNEUROSCI.
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http://www.jneurosci.org/lookup/doi/10.1523/JNEUROSCI.1350-1
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http://dx.doi.org/10.1523/JNEUROSCI.1350-18.2018DOI Listing
November 2018
6 Reads

Cerebellar arteriovenous malformation presenting with recurrent positional vertigo.

J Neurol 2018 Oct 30. Epub 2018 Oct 30.

Institute of Clinical Neurosciences, Royal Prince Alfred Hospital, Central Clinical School, University of Sydney, Sydney, NSW, Australia.

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http://dx.doi.org/10.1007/s00415-018-9103-5DOI Listing
October 2018

Imaging biomarkers of behavioral impairments: A pilot micro-positron emission tomographic study in a rat electrical post-status epilepticus model.

Epilepsia 2018 Dec 28;59(12):2194-2205. Epub 2018 Oct 28.

Institute of Pharmacology, Toxicology, and Pharmacy, Ludwig Maximilian University of Munich, Munich, Germany.

Objective: In patients with epilepsy, psychiatric comorbidities can significantly affect the disease course and quality of life. Detecting and recognizing these comorbidities is central in determining an optimal treatment plan. One promising tool in detecting biomarkers for psychiatric comorbidities in epilepsy is positron emission tomography (PET). Read More

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http://doi.wiley.com/10.1111/epi.14586
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http://dx.doi.org/10.1111/epi.14586DOI Listing
December 2018
7 Reads

Apamin treatment accelerates equilibrium recovery and gaze stabilization in unilateral vestibular neurectomized cats: Cellular and behavioral aspects.

Neuropharmacology 2019 Jan 24;144:133-142. Epub 2018 Oct 24.

Aix Marseille Université-CNRS, Laboratory of Sensory and Cognitive Neuroscience, LNSC UMR 7260. Team Pathophysiology and Therapy of Vestibular Disorders, Marseille, France; Centre Saint-Charles, Case B; 3 Place Victor Hugo 13331 Marseille cedex 03, France.

Sudden and complete unilateral loss of peripheral vestibular inputs evokes characteristic vestibular syndrome comprised of posturo-locomotor, oculomotor, vegetative and cognitive symptoms. Subsequently to the vestibular insult, a neurophysiological process called central vestibular compensation promotes the progressive restoration of the posture and balance. The modulation of the excitability of vestibular secondary neurons has been demonstrated to be a key process of this mechanism. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S00283908183081
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http://dx.doi.org/10.1016/j.neuropharm.2018.10.029DOI Listing
January 2019
5 Reads

[Acute vestibular disorder in the elderly: stroke or peripheral vestibulopathy].

Zh Nevrol Psikhiatr Im S S Korsakova 2018 ;118(6. Vyp. 2):46-49

Russian Medical Academy of Continuous Professional Education, Moscow, Russia.

Acute vestibular disorder is a frequent cause of urgent hospitalization in elderly patients. A CNS vascular disorder is often thought to be a cause of vertigo and a patient is diagnosed with stroke or transitory ischemic attack (TIA) or vertebral-basilar insufficiency. Despite the higher risk of cerebrovascular disease in the elderly, stroke and TIA are not the only cause of acute vestibular disorder. Read More

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http://dx.doi.org/10.17116/jnevro201811806246DOI Listing
January 2018
5 Reads

An fMRI study of visuo-vestibular interactions following vestibular neuritis.

Neuroimage Clin 2018 9;20:1010-1017. Epub 2018 Oct 9.

Neuro-otology Unit, Division of Brain Sciences, Charing Cross Hospital, Imperial College London, London W6 8RP, UK. Electronic address:

Vestibular neuritis (VN) is characterised by acute vertigo due to a sudden loss of unilateral vestibular function. A considerable proportion of VN patients proceed to develop chronic symptoms of dizziness, including visually induced dizziness, specifically during head turns. Here we investigated whether the development of such poor clinical outcomes following VN, is associated with abnormal visuo-vestibular cortical processing. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S22131582183031
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http://dx.doi.org/10.1016/j.nicl.2018.10.007DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6197146PMC
October 2018
13 Reads

FDG PET/CT in a Case of Dural Amyloidoma.

Clin Nucl Med 2018 Dec;43(12):925-929

Department of Nuclear Medicine, Changhai Hospital, Second Military Medical University, Shanghai, China.

Dural amyloidoma is an unusual presentation of central nervous system amyloidosis. A 49-year-old woman presented with 1-month history of repeated episodes of vertigo. Precontrast MRI showed dural thickening over right frontal convexity with signal intensity similar to white matter. Read More

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http://Insights.ovid.com/crossref?an=00003072-900000000-9743
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http://dx.doi.org/10.1097/RLU.0000000000002304DOI Listing
December 2018
3 Reads

Frequency of audiological complaints in patients with fibromyalgia syndrome and its relationship with oxidative stress.

Niger J Clin Pract 2018 Oct;21(10):1271-1277

Department of Clinic Biochemistry, Faculty of Medicine, Sütçü İmam University, Kahramanmaraş, Turkey.

Aim: Central sensitization-related neuroaudiological symptoms are frequently seen in patients with fibromyalgia syndrome (FMS). This study aimed to evaluate the audiological signs and symptoms in patients with FMS and explore their relationship with oxidative stress markers.

Methods: This prospective controlled cross-sectional study compared the serum myeloperoxidase, superoxide dismutase, glutathione peroxidase (GPx), nitric oxide (NO), and malondialdehyde (MDA) concentrations in 44 patients with FMS diagnosed according to the 2010 American College of Rheumatology criteria and 44 healthy volunteers. Read More

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http://dx.doi.org/10.4103/njcp.njcp_95_18DOI Listing
October 2018
4 Reads

Peripheral Vestibular Disorders: An Epidemiologic Survey in 70 Million Individuals.

Otol Neurotol 2019 Jan;40(1):88-95

Department of Otorhinolaryngology, Head and Neck Surgery, Medical Faculty Mannheim, University Medical Centre Mannheim, University of Heidelberg, Heidelberg.

Background: Dizziness is a common complaint in medicine. Nevertheless, there is a lack of valid data concerning the age and gender distribution of dizziness disorders within a larger population. Therefore, the aim of the present study is to undertake a representative epidemiological survey that examines all age groups of an entire population and describes the age and gender distribution of the most common peripheral vestibular disorders. Read More

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http://Insights.ovid.com/crossref?an=00129492-900000000-9661
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http://dx.doi.org/10.1097/MAO.0000000000002013DOI Listing
January 2019
2 Reads

The effective clinical outcomes of the Gufoni maneuver used to treat 91 vertigo patients with apogeotropic direction-changing positional nystagmus (apo-DCPN).

Medicine (Baltimore) 2018 Sep;97(39):e12363

Department of Neurology, Zhejiang Provincial People's Hospital.

This study aimed to observe and analyze the effects and outcomes of patients with apogeotropic direction-changing positional nystagmus (apo-DCPN) who received Gufoni maneuver.A total of 91 patients with positional vertigo admitted to the specialized dizziness clinic in Zhejiang Provincial People's Hospital from February 2014 to August 2017 were included. The immediate treatment responses to the Gufoni maneuver were observed and recorded. Read More

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http://Insights.ovid.com/crossref?an=00005792-201809280-0003
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http://dx.doi.org/10.1097/MD.0000000000012363DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6181626PMC
September 2018
2 Reads

Autoimmune vertigo: an update on vestibular disorders associated with autoimmune mechanisms.

Immunol Res 2018 Oct 1. Epub 2018 Oct 1.

Department of Sense Organs, Sapienza University of Rome, Viale del Policlinico 155, 00100, Rome, Italy.

The role of the immune system in mediating cochleovestibular pathologies has received increasing attention in recent years. Autoimmune vertigo may be an invalidating condition and may worsen the quality of life of affected patients, especially in the cases of delayed diagnosis. Since the etiopathogenesis is still not clear, also the treatment is not yet completely delineated. Read More

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http://dx.doi.org/10.1007/s12026-018-9023-6DOI Listing
October 2018
7 Reads

Trichosporon inkin meningitis in Northeast Brazil: first case report and review of the literature.

BMC Infect Dis 2018 Sep 18;18(1):470. Epub 2018 Sep 18.

Centro de Ciências da Saúde, Laboratório de Micologia Médica e Molecular, Departamento de Análises Clínicas e Toxicológicas, Universidade Federal do Rio Grande do Norte, Rua Gal. Gustavo Cordeiro de Faria S/N, Petrópolis, Natal, Rio Grande do Norte, Brazil.

Background: Trichosporon species may colonize the skin, respiratory tract and gastrointestinal tract of human beings. The yeast is recognized as etiological agent of white piedra, a superficial mycosis. Nevertheless, immunocompromised hosts may develop invasive Trichosporonosis. Read More

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http://dx.doi.org/10.1186/s12879-018-3363-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145100PMC
September 2018
1 Read

Dabrafenib and Trametinib Treatment for Erdheim-Chester Disease With Brain Stem Involvement.

Mayo Clin Proc Innov Qual Outcomes 2018 Sep 4;2(3):303-308. Epub 2018 Jul 4.

Department of Hematology and Oncology, University of Miami Miller School of Medicine, Miami, FL.

Erdheim-Chester disease (ECD) is a rare form of non-Langerhans cell histiocytosis characterized by infiltration of organs by CD68 and CD1a lipid-laden histiocytes, including the central nervous system in more than a third of patients. Molecular analysis of ECD samples has demonstrated the prevalence of V600E mutations as high as 54%. Recently, vemurafenib became the only Food and Drug Administration-approved treatment for patients with ECD who carry the V600E mutation. Read More

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http://dx.doi.org/10.1016/j.mayocpiqo.2018.05.001DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6132217PMC
September 2018
2 Reads

Role of Electronystagmography in Diagnosis of Secondary BPPV in Elderly Patients with Vertigo: A Retrospective Study.

Indian J Otolaryngol Head Neck Surg 2018 Sep 13;70(3):428-433. Epub 2018 Jul 13.

2Department of ENT, MGM Medical College and MY Hospital, Indore, M.P. India.

Elderly population is frequently affected by vertigo which affects their mobility and makes them vulnerable to fall and other morbidities. Often these patient visit neurologist and are often subjected to CT scan, MRI brain etc. to rule out a central cause of vertigo; whereas majority of these patients suffer from vestibular cause of vertigo. Read More

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http://link.springer.com/10.1007/s12070-018-1449-6
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http://dx.doi.org/10.1007/s12070-018-1449-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6127064PMC
September 2018
8 Reads

Ptosis and Mass Like Lesions in Behçet's Disease: A Rare Presentation.

Arch Rheumatol 2018 Jun 16;33(2):221-224. Epub 2017 Oct 16.

Department of Rheumatology, Ondokuz Mayıs University, Faculty of Medicine, Samsun, Turkey.

In this article, we describe a case of neuro-Behçet's disease presenting with unilateral ptosis and facial paresis due to an intracranial mass lesion. A 25-year-old male patient with a history of Behçet's disease presented with headache, vertigo, double vision, ptosis in his right eyelid and slurred speech. Cranial magnetic resonance imaging scan revealed a right-sided capsulothalamic lesion, which was extending to the right cerebral pedicle, pons and superior cerebellar pedicle. Read More

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http://dx.doi.org/10.5606/ArchRheumatol.2018.6515DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6117147PMC
June 2018
7 Reads

Evaluation of Hearing and Balance Functions of Patients with Sickle Cell Anemia.

Audiol Neurootol 2018 11;23(2):122-125. Epub 2018 Sep 11.

Hatay Mustafa Kemal University Medicine, Faculty Ear-Nose-Throat Department, Hatay, Turkey.

Introduction: Sickle cell anemia is a disease characterized by a wide vaso-occlusive incident from micro-vascular incident to muscularactivity. The cochlear function can also get affected by this vaso-occlusion.

Objective: It is aimed at determining what kind of effects sickle cell anemia has on hearing and balance system. Read More

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http://dx.doi.org/10.1159/000492171DOI Listing
September 2018
1 Read

Usage of the HINTS exam and neuroimaging in the assessment of peripheral vertigo in the emergency department.

J Otolaryngol Head Neck Surg 2018 Sep 10;47(1):54. Epub 2018 Sep 10.

Department of Otolaryngology- Head and Neck Surgery, University of Ottawa, 501 Smyth Rd, Ottawa, ON, K1H 8L6, Canada.

Background: Dizziness is a common presenting symptom in the emergency department (ED). The HINTS exam, a battery of bedside clinical tests, has been shown to have greater sensitivity than neuroimaging in ruling out stroke in patients presenting with acute vertigo. The present study sought to assess practice patterns in the assessment of patients in the ED with peripherally-originating vertigo with respect to utilization of HINTS and neuroimaging. Read More

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http://dx.doi.org/10.1186/s40463-018-0305-8DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6131950PMC
September 2018

Physical therapy examination and management of a 48-year-old male with vertigo, cephalalgia, and cervicalgia secondary to unilateral vestibular hypofunction.

Physiother Theory Pract 2018 Sep 10:1-12. Epub 2018 Sep 10.

c Department of Physical Therapy , Angelo State University, Texas Tech University System , San Angelo , TX , USA.

Purpose: This case report presents evidence-based physical therapy assessments and interventions for a patient with unilateral vestibular hypofunction (UVH). UVH is the result of peripheral vestibular dysfunction in the inner ear.

Case Description: The patient was a 48-year-old male with symptoms of dizziness, cephalalgia, and cervicalgia. Read More

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http://dx.doi.org/10.1080/09593985.2018.1517848DOI Listing
September 2018
2 Reads

Vascular vertigo: updates.

J Neurol 2018 Sep 5. Epub 2018 Sep 5.

Department of Neurology, Seoul National University College of Medicine, Seoul, Republic of Korea.

Discriminating strokes in patients with acute dizziness/vertigo is challenging especially when other symptoms and signs of central nervous involvements are not evident. Despite the developments in imaging technology over the decades, a significant proportion of acute strokes may escape detection on imaging especially during the acute phase or when the lesions are small. Thus, small strokes causing isolated dizziness/vertigo would have a higher chance of misdiagnosis in the emergency department. Read More

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http://dx.doi.org/10.1007/s00415-018-9040-3DOI Listing
September 2018
1 Read

Aminopyridines and acetyl-DL-leucine: new therapies in cerebellar disorders.

Curr Neuropharmacol 2018 Sep 4. Epub 2018 Sep 4.

Department of Neurology, German Center for Vertigo and Balance Disorders, and Institute for Clinical Neurosciences, University Hospital Munich, Campus Grosshadern, Munich. Germany.

Cerebellar ataxia is a frequent and often disabling syndrome severely impairing motor functioning and quality of life. Patients suffer from reduced mobility, and restricted autonomy, experiencing an even lower quality of life than, e.g. Read More

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http://dx.doi.org/10.2174/1570159X16666180905093535DOI Listing
September 2018
4 Reads

[Neuro-otology: at the borders of ear and brain].

Nervenarzt 2018 Oct;89(10):1106-1114

Neurologische Klinik und Poliklinik, Universitätsklinikum Ludwig-Maximilians-Universität München, Campus Großhadern, Marchioninistr. 15, 81377, München, Deutschland.

Vertigo and dizziness are frequent chief complaints in clinical practice. Symptoms may originate from otological, neurological, medical and psychiatric etiologies, which poses an interdisciplinary challenge. Systematic analysis of case history and clinical examination generally allow classification into peripheral-, central- or non-vestibular disorders. Read More

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http://dx.doi.org/10.1007/s00115-018-0598-xDOI Listing
October 2018
4 Reads

Gravity-Independent Upbeat Nystagmus in Syndrome of Anti-GAD Antibodies.

Cerebellum 2018 Aug 22. Epub 2018 Aug 22.

Department of Neurology, Cleveland VA Medical Center, University Hospitals, Cleveland, OH, 44022, USA.

An autoimmune disorder of the central nervous system, stiff person syndrome, frequently presents with increased titers of 65KD anti-glutamic acid decarboxylase (anti-GAD) antibodies. The clinical phenomenology of this syndrome includes stiffness, ataxia, vertigo due to horizontal gaze-evoked and downbeat vertical nystagmus, and dysmetria of saccades and reaching movements. Here, we describe a novel phenomenology of syndrome of anti-GAD antibody, non-position-dependent upbeat nystagmus and superimposed horizontal gaze-evoked nystagmus. Read More

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http://link.springer.com/10.1007/s12311-018-0972-z
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http://dx.doi.org/10.1007/s12311-018-0972-zDOI Listing
August 2018
16 Reads

Mining healthcare data for markers of the multiple sclerosis prodrome.

Mult Scler Relat Disord 2018 Oct 8;25:232-240. Epub 2018 Aug 8.

Medicine (Neurology), University of British Columbia and The Djavad Mowafaghian Centre for Brain Health, 2215 Wesbrook Mall, Vancouver, BC V6T 1Z3, Canada. Electronic address:

Background: Previous studies suggest the existence of a prodromal period in multiple sclerosis, but little is known about the phenotypic characteristics. This study aims to characterize the multiple sclerosis (MS) prodrome using data mining analytics in the healthcare setting.

Methods: We identified people with MS and matched general population controls using health administrative data in two Canadian provinces (British Columbia and Saskatchewan). Read More

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http://dx.doi.org/10.1016/j.msard.2018.08.007DOI Listing
October 2018

[Paradigm shift in management of patients with vertigo and imbalance].

Ideggyogy Sz 2018 Jul;71(7-08):221-235

Petz Aladár Megyei Oktató Kórház, Fül-Orr-Gégészeti és Fej-, Nyaksebészeti Osztály, Gyôr.

Dizziness is one of the most common causes of medical visits. Management of the dizzy patient may be challenging both for the general practitioner, in emergency departments, and special clinics, as behind a seemingly homogeneous clinical presentation several very different etiologies may occur. Research of the last two century enriched our knowledge about physiology and pathophysiology of the vestibular system. Read More

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http://www.elitmed.hu/kiadvanyaink/ideggyogyaszati-szemle/sz
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http://dx.doi.org/10.18071/isz.71.0221DOI Listing
July 2018
21 Reads

Characterization of vertigo and hearing loss in patients with Fabry disease.

Orphanet J Rare Dis 2018 Aug 15;13(1):137. Epub 2018 Aug 15.

Department of Otorhinolaryngology, Head and Neck Surgery "Otto Körner", University Medical Center Rostock, Doberaner Straße 137-139, D-18057, Rostock, Germany.

Background: Fabry Disease (FD) is an X-linked hereditary lysosomal storage disorder which leads to a multisystemic intralysosomal accumulation of globotriaosylceramid (Gb3). Besides prominent renal and cardiac organ involvement, patients commonly complain about vestibulocochlear symptoms like high-frequency hearing loss, tinnitus and vertigo. However, comprehensive data especially on vertigo remain scarce. Read More

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http://dx.doi.org/10.1186/s13023-018-0882-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6094894PMC
August 2018
1 Read

Unique Clinical Language Patterns Among Expert Vestibular Providers Can Predict Vestibular Diagnoses.

Otol Neurotol 2018 Oct;39(9):1163-1171

Department of Otolaryngology and Communication Sciences, Medical College of Wisconsin, Milwaukee, Wisconsin.

Objective: To identify novel language usage by expert providers predictive of specific vestibular conditions.

Study Design: Retrospective chart review and natural language processing. Level IV. Read More

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http://dx.doi.org/10.1097/MAO.0000000000001930DOI Listing
October 2018
12 Reads

Sudden hearing loss as an early detector of multiple sclerosis: a systematic review.

Eur Rev Med Pharmacol Sci 2018 Jul;22(14):4611-4624

Neurology Department, San Camillo Hospital IRCCS, Venice, Italy.

Objective: To evaluate whether Sudden Sensorineural Hearing Loss (S-SNHL) may be an early symptom of Multiple Sclerosis (MS).

Materials And Methods: A systematic review was conducted using the following keywords: "Multiple sclerosis, hearing loss, sudden hearing loss, vertigo, tinnitus, magnetic resonance imaging, otoacoustic emission, auditory brainstem responses, white matter lesions, sensorineural hearing loss, symptoms of MS and otolaryngology, nerve disease and MS". Only the articles that included results of at least one auditory test and MRI were considered. Read More

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http://dx.doi.org/10.26355/eurrev_201807_15520DOI Listing
July 2018
2 Reads

Efficacy of Repositioning Therapy in Patients With Benign Paroxysmal Positional Vertigo and Preexisting Central Neurologic Disorders.

Front Neurol 2018 29;9:486. Epub 2018 Jun 29.

Department of Neurology, School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan.

With the exception of migraines, benign paroxysmal positional vertigo (BPPV) in patients with preexisting central neurologic disorders (CND) is rarely discussed in the literature. Demographic features of this patient group and the efficacy of repositioning therapy are still unknown. We hypothesized that a CND may alter the function of the central vestibular pathway, thus changing the pattern of BPPV and outcomes of repositioning. Read More

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http://dx.doi.org/10.3389/fneur.2018.00486DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6037198PMC
June 2018
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Utility of thermographic measurements of laterality of body surface temperature to prevent misdiagnosis of acute Wallenberg's syndrome.

Brain Behav 2018 Aug 11;8(8):e01040. Epub 2018 Jul 11.

Department of Neurology, Kanto Central Hospital, Tokyo, Japan.

Introduction: Acute Wallenberg's syndrome (WS) is sometimes misdiagnosed as a nonstroke disease including auditory vertigo, and careful neurological examination is required for a precise diagnosis. Lateral difference of body surface temperature (BST) had been reported as a symptom of WS, although further details of this symptom are currently lacking. Our aim was to investigate the laterality of BST of patients with acute WS using thermography and the usefulness of thermography to detect acute WS. Read More

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http://dx.doi.org/10.1002/brb3.1040DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6085920PMC
August 2018
13 Reads

Posturography studies in patients with central and mixed vertigo Summary.

Otolaryngol Pol 2018 May;72(3):19-25

Clinic of Otolaryngology and Laryngological Oncology of the 2nd Department of Otolaryngology, Medical University of Lodz; Head of the Clinic and the Department: Professor J. Olszewski MD, PhD; Łódź, Poland.

Introduction: The aim of the study was to compare the results of posturography in patients with central and mixed vertigo.

Material And Methods: 50 patients (40 female and 10 male) aged between 26-47 complaining of vertigo were examined during their hospitalization in the Department of Otolaryngology, Laryngological Oncology, Audiology and Phoniatrics, Medical University of Lodz in 2014. The subjects were divided into two groups: I - 26 patients (23 female and 3 male) with central vertigo, II - 24 patients (17 female and 7 male) with mixed vertigo. Read More

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http://dx.doi.org/10.5604/01.3001.0011.7256DOI Listing
May 2018
11 Reads

[Advances in peripheral vestibular diseases with downbeat nystagmus].

Authors:

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(13):1034-1037

Downbeat nystagmus is not rare and usually considered as a central nervous system disease. However, there are a lot of diseases that present with downbeat nystagmus only or downbeat component in nystagmus, including peripheral and central vestibular diseases and Chiari malformations. This review will briefly summarize the vestibulo ocular reflexes and the mechanisms of the downbeat nystagmus with a peripheral origin, and then common vestibular disease such as the anterior semicircular canal benign paroxysmal positional vertigo,posterior semicircular canal benign paroxysmal positional vertigo, posterior semicircular canal light cupula, Meniere's disease and inferior vestibular neuritis are reviewed. Read More

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http://www.cnki.net/kcms/doi/10.13201/j.issn.1001-1781.2018.
Publisher Site
http://dx.doi.org/10.13201/j.issn.1001-1781.2018.13.020DOI Listing
July 2018
14 Reads

[Short-term outcomes of Li's repositioning maneuver of different age groups patients of horizontal semicircular canal canalithiasis benign paroxysmal positional vertigo].

Authors:
J Ju J R Li S Z Zou

Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2018 Jul;32(13):1009-1012

Central of Otolaryngology Head and Neck Surgery, Navy General Hospital, Beijing,100048,China.

To analyse whether there is statistical difference between different age group short-term outcomes of horizontal semicircular canal canalithiasis benign paroxysmal positional vertigo (HC-BPPV) patients treated by Li's repositioning maneuver.Since October 2009 to July 2017, we included 169 unilateral HC-BPPV patients treated by Li's repositioning maneuver. Then we recorded and analyse 3-day and 1-week outcomes. Read More

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http://dx.doi.org/10.13201/j.issn.1001-1781.2018.13.012DOI Listing
July 2018
7 Reads

Central cause of positioning vertigo.

Pract Neurol 2018 Dec 3;18(6):492-493. Epub 2018 Jul 3.

Department of Neurology, Tauranga Hospital, Tauranga, New Zealand.

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http://dx.doi.org/10.1136/practneurol-2018-001987DOI Listing
December 2018
1 Read

[A case of neurosarcoidosis with recurrent brainstem infarction, obstructive hydrocephalus and brainstem atrophy].

Rinsho Shinkeigaku 2018 Jul 30;58(7):445-450. Epub 2018 Jun 30.

Department of Neurology, Osaka City University.

We report the case of a 42-year-old female with neurosarcoidosis who was hospitalized in year 2017 for gait disturbance. In 2011, she suddenly had vertigo that lasted for a few days. In 2013, she noticed left hemiplegia. Read More

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http://dx.doi.org/10.5692/clinicalneurol.cn-001155DOI Listing
July 2018
3 Reads