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Sleep Sci 2022 Apr-Jun;15(2):259-264

Amir Alam Hospital, Tehran University of Medical Sciences, Otorhinolaryngology Research Center - Tehran - Iran.

Introduction: Patients with migraine, who suffer from sleep apnea, whether obstructive or central, might lead to treatment-resistant headaches. In this study, we have reported a 42-year-old man with a confirmed treatment-resistant migraine headaches and hemiplegic attacks, who was referred to our sleep clinic for evaluation of sleep breathing problems.

Case Report: The patient had recurrent attacks of migraine headaches with hemiplegic attacks. Read More

Children (Basel) 2022 Jun 17;9(6). Epub 2022 Jun 17.

Department of Pediatrics, Taipei Tzu Chi Hospital, Buddhist Tzu Chi Medical Foundation, New Taipei City 23142, Taiwan.

Obstructive sleep apnea syndrome (OSAS) is one of the most common comorbidities in patients with Prader-Willi syndrome (PWS) and causes significant consequences. This observational study was conducted to investigate the progression of OSAS in pediatric patients with PWS, who had not undergone upper airway surgery, through a longitudinal follow-up of their annual polysomnography results. Annual body mass index (BMI), BMI z-score, sleep efficiency and stages, central apnea index (CAI), obstructive apnea-hypopnea index (OAHI), and oxygen saturation nadir values were longitudinally analyzed. Read More

Laryngoscope Investig Otolaryngol 2022 Jun 25;7(3):885-893. Epub 2022 Apr 25.

Department of Otolaryngology, Head and Neck Surgery, The Second Xiangya Hospital Central South University Changsha Hunan China.

Background: Patients with obstructive sleep apnea (OSA) are more likely to suffer from hypertension. At the same time, the serum levels of matrix metalloproteinase-9 (MMP-9) and nitric oxide (NO) in patients with OSA are also changed in OSA patients. We investigated the correlation between serum levels of MMP-9, NO in patients with OSA and their association with hypertension in those patients, and the effects of continuous positive airway pressure therapy (CPAP) on these serum biomarkers and blood pressure. Read More

JAMA Surg 2022 Jun 22. Epub 2022 Jun 22.

Division of Digestive Surgery and Urology, Turku University Hospital, Turku, Finland.

Importance: Long-term results from randomized clinical trials comparing laparoscopic sleeve gastrectomy (LSG) with laparoscopic Roux-en-Y-gastric bypass (LRYGB) are limited.

Objective: To compare long-term outcomes of weight loss and remission of obesity-related comorbidities and the prevalence of gastroesophageal reflux symptoms (GERD), endoscopic esophagitis, and Barrett esophagus (BE) after LSG and LRYGB at 10 years.

Design, Setting, And Participants: This 10-year observational follow-up evaluated patients in the Sleeve vs Bypass (SLEEVEPASS) multicenter equivalence randomized clinical trial comparing LSG and LRYGB in the treatment of severe obesity in which 240 patients aged 18 to 60 years with median body mass index of 44. Read More

Int J Pediatr Otorhinolaryngol 2022 Jun 14;159:111208. Epub 2022 Jun 14.

Department of Otorhinolaryngology-Head and Neck Surgery, Soonchunhyang University College of Medicine, Bucheon Hospital, Bucheon, Gyeonggi-do, Republic of Korea. Electronic address:

Objectives: This study aimed to identify the effectiveness of respiratory mechanic instability (RMI) in the diagnosis of pediatric obstructive sleep apnea syndrome (OSAS). We sought to evaluate the correlations of RMI with sleep-related parameters and determine the effectiveness of using RMI for diagnosing OSAS in children.

Methods: Children who underwent polysomnography (PSG) for various reasons were enrolled in this study. Read More

Sleep Breath 2022 Jun 20. Epub 2022 Jun 20.

Department of Internal Medicine II - Cardiology, Pneumology and Angiology, University Hospital Bonn, Bonn, Germany.

Purpose: The relationship between chronic heart failure and sleep-disordered breathing (SDB) has been frequently described. However, little is known about the association of mitral regurgitation (MR) and SDB or the impact of transcatheter mitral valve repair (TMVR) on SDB. Our aims were first to determine the prevalence of SDB in patients with MR, and second to determine the effect of TMVR on SDB. Read More

Sleep Med 2022 Jun 9;97:64-72. Epub 2022 Jun 9.

2nd Department of Respiratory Medicine, Institute of Tuberculosis and Lung Diseases, Warsaw, Poland.

Objective: In 2010, a questionnaire-based study on obstructive sleep apnea (OSA) management in Europe identified differences regarding reimbursement, sleep specialist qualification, and titration procedures. Now, 10 years later, a follow-up study was conducted as part of the ESADA (European Sleep Apnea Database) network to explore the development of OSA management over time.

Methods: The 2010 questionnaire including questions on sleep diagnostic, reimbursement, treatment, and certification was updated with questions on telemedicine and distributed to European Sleep Centers to reflect European OSA management practice. Read More

Lung 2022 Jun 18. Epub 2022 Jun 18.

Instituto de Doenças Do Tórax (IDT), Universidade Federal Do Rio de Janeiro (UFRJ), Rua Professor Rodolpho Paulo Rocco, 255 - 1° andar - sala 01D 58/60, Rio de Janeiro, RJ, CEP, 21941-913, Brazil.

Purpose: To evaluate the frequency of sleep-disordered breathing (SDB) and predictors of the presence of nocturnal desaturation in adults with pulmonary arterial hypertension and chronic thromboembolic pulmonary hypertension.

Methods: Outpatients with a hemodynamic diagnosis of precapillary pulmonary hypertension who underwent portable polysomnography were evaluated. Diagnosis and severity of SDB were assessed using three well-established respiratory disturbance index (RDI) thresholds: 5. Read More

Int J Pediatr Otorhinolaryngol 2022 Jun 2;159:111194. Epub 2022 Jun 2.

Department of Otolaryngology, Shandong Provincial Hospital Affiliated to Shandong First Medical University, No. 324 Jingwuweiqi Road, 250021, Jinan, Shandong Province, China. Electronic address:

Background: Obstructive sleep apnea-hypopnea syndrome (OSAHS) is a sleep disorder causing cognitive impairments.

Aims: We use the auditory verbal learning test (AVLT), clock drawing test (CDT), Wechsler intelligence scale for children (WISC) and Montreal cognitive assessment (MoCA) to evaluate the memory and spatial impairments of OSHAS in 6-12 years old children patients with different severity.

Material And Methods: A total of 137 children of snoring were enrolled following the inclusion criteria of this study. Read More

High Alt Med Biol 2022 Jun;23(2):165-172

Center for Investigation and Research in Sleep, University Hospital of Lausanne, Lausanne, Switzerland.

Heiniger, Grégory, Simon Walbaum, Claudio Sartori, Alban Lovis, Marco Sazzini, Andrew Wellman, and Raphael Heinzer. Altitude-Induced Sleep Apnea Is Highly Dependent on Ethnic Background (Sherpa Vs. Tamang). Read More

Curr Psychiatry Rep 2022 Jun 11. Epub 2022 Jun 11.

Department of Medicine, Baylor College of Medicine, Houston, USA.

Purpose Of Review: This article will provide a brief review of most recent findings of sleep, insomnia, obstructive sleep apnea, and restless leg syndrome during pregnancy.

Recent Findings: Recent meta-analyses have found that 38.2% of pregnant women experience insomnia, 15% experience obstructive sleep apnea, and 20% experience restless leg syndrome. Read More

Int J Environ Res Public Health 2022 06 6;19(11). Epub 2022 Jun 6.

Department of Physics and Applied Mathematics, Universidad de Navarra, 31009 Pamplona, Spain.

Obstructive sleep apnea (OSA) is a common sleep disorder characterized by repetitive upper airway obstruction, intermittent hypoxemia, and recurrent awakenings during sleep. The most used treatment for this syndrome is a device that generates a positive airway pressure-Continuous Positive Airway Pressure (CPAP), but it works continuously, whether or not there is apnea. An alternative consists on systems that detect apnea episodes and produce a stimulus that eliminates them. Read More

Sleep Med 2022 May 23;97:1-9. Epub 2022 May 23.

Medical Research Center Oulu Brain Health, Oulu University Hospital, Research Unit of Clinical Neuroscience, Oulu University of Oulu, Oulu, Finland. Electronic address:

Background: The aim of the study was to investigate whether findings in cardiorespiratory polygraphy had an association with stroke mortality or ischemic event recurrence after ischemic stroke.

Methods: We prospectively studied 204 ischemic stroke patients who underwent cardiorespiratory polygraphy within the first 48 h after the symptom onset. We followed all these patients for a median of 6. Read More

Praxis (Bern 1994) 2022 ;111(8):436-443

Universitätsklinik für Pneumologie, Inselspital, Universitätsspital Bern, Universität Bern, Bern, Schweiz.

Treatment-Emergent Central Sleep Apnea - Detection and Treatment In treatment-emergent central sleep apnea (TECSA), affected patients with obstructive sleep apnea newly develop central sleep apnea (AHI central ≥5/h) under therapy with positive pressure ventilation which cannot be explained by other causes. The pathophysiology of TECSA is incompletely understood. PaCO2 and the associated apnea threshold seem to play a central role. Read More

Praxis (Bern 1994) 2022 ;111(8):433-434

KSM Klinik für Schlafmedizin, Bad Zurzach und Airport Zürich, Schweiz.

Sleep 2022 Jun 7. Epub 2022 Jun 7.

Department of Psychiatry and Human Behavior, University of California, Irvine, CA, USA.

Study Objectives: Fast frequency sleep spindles are reduced in aging and Alzheimer's disease (AD), but the mechanisms and functional relevance of these deficits remains unclear. The study objective was to identify AD biomarkers associated with fast sleep spindle deficits in cognitively unimpaired older adults at risk for AD.

Methods: Fifty-eight cognitively unimpaired, β-amyloid negative, older adults (mean±SD; 61. Read More

Saf Health Work 2022 Jun 5;13(2):148-154. Epub 2022 Feb 5.

CENTRALABS, University of Cagliari, Engineering Labs, SS 554, Km 4,500, 09042 Monserrato, Italy.

Background: Bus driving is a mentally demanding activity that requires prolonged attention to ensure safety. The aim of the study was to assess mental fatigue caused by driving a public bus and to find a profile of workers at higher risk.

Methods: We evaluated changes of critical flicker fusion (CFF) (index of central arousal) and heart rate variability (HRV) (index of autonomic balance) in a 6-hour driving shift on a real route, in 31 professional bus drivers, and we tested the influence of personal factors such as sleep quality, BMI, and age. Read More

Semin Ophthalmol 2022 Jun 3:1-9. Epub 2022 Jun 3.

Department of Ophthalmology, Parke Street Specialist Centre, Katoomba, NSW, Australia.

Introduction: A 43-year-old Caucasian male presented to our ophthalmology clinic with blurry vision and metamorphopsia in his right eye, 24 hours after receiving the first dose of the Pfizer-BioNTech COVID-19 vaccine.

Methods: Clinical examination and imaging tests were consistent with acute unilateral central serous chorioretinopathy (CSCR) that completely resolved after 2 months without any treatment. He had no significant ophthalmic or medical history. Read More

Ann Med 2022 12;54(1):1578-1589

Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, China.

Background: Obstructive sleep apnea (OSA) and inflammation are closely related. This study aimed to evaluate the associations and causal effect between C-reactive protein (CRP) and tumour necrosis factor-alpha (TNF-α) levels andOSA.

Methods: Pooled analysis was conducted to compare the expression differences of CRP and TNF-α between OSA patients with different severity and controls, and between continuous positive airway pressure (CPAP) and non-CPAP interventions for OSA patients. Read More

J Clin Sleep Med 2022 May 31. Epub 2022 May 31.

Institute of Neurology, Fondazione Policlinico Universitario "Agostino Gemelli", IRCCS, Università Cattolica del Sacro Cuore, Rome, Italy.

Study Objectives: The main aim was to evaluate the prevalence of sleep-disordered breathing (SDB) in patients with Chiari II malformation (CM-II). The secondary objectives were to evaluate the association between SDB, morphological abnormalities and neurological symptoms and to review the literature of patients with SDB and CM-II.

Methods: The study has a cross-sectional, case-control design. Read More

Laryngoscope 2022 Jun 1. Epub 2022 Jun 1.

Division of Pulmonary Medicine and the Sleep Center, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio, USA.

Laryngoscope 2022 Jun 1. Epub 2022 Jun 1.

Department of Surgery, Section of Otolaryngology-Head and Neck Surgery, The University of Chicago Medicine, Chicago, Illinois, USA.

Sleep Breath 2022 May 31. Epub 2022 May 31.

Division of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of California San Diego (UCSD), 9300 Campus Point Drive #7381, La Jolla, CA, 92037, USA.

Purpose: Sleep disordered breathing in decompensated heart failure has physiological consequences (e.g., intermittent hypoxemia) that may predispose to subclinical myocardial injury, yet a temporal relationship between sleep apnea and troponin elevation has not been established. Read More

Eur J Clin Invest 2022 May 31:e13821. Epub 2022 May 31.

Department of Respiratory Medicine, Xiangya Hospital, Central South University, Changsha, Hunan, China.

Background: Comorbidity of obstructive sleep apnea (OSA) and heart failure (HF) is becoming increasingly common. This is a global analysis of positive airway pressure (PAP) efficacy for the cardiovascular outcomes in those HF Patients with comorbid OSA.

Methods: Related randomized controlled trials were included. Read More

Sleep Med 2022 Aug 18;96:107-112. Epub 2022 May 18.

Alberta Children's Hospital, 28 Oki Drive NW, Calgary, AB, T3B 6A8, Canada; Department of Pediatrics, Cumming School of Medicine, University of Calgary, Alberta, Canada. Electronic address:

Study Objectives: The gold standard test for diagnosis of sleep related breathing disorders (SRBD) in children is diagnostic polysomnography (PSG). This is often followed by a titration PSG to identify optimal non-invasive ventilation (NIV) pressures. Access to pediatric PSG is limited, resulting in delays to diagnosis and initiation of treatment. Read More

Biomed Rep 2022 Jun 1;16(6):45. Epub 2022 Apr 1.

Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen 40002, Thailand.

Obstructive sleep apnea (OSA) is a common disease and related to several cardiovascular diseases. Treatment with a continuous positive airway pressure (CPAP) machine is effective. However, not all patients with OSA purchase a CPAP machine for personal use. Read More

Sleep Disord 2022 17;2022:2590337. Epub 2022 May 17.

Department of Otolaryngology-Head and Neck Surgery, University of Texas Southwestern Medical Center, Dallas, Texas, USA.

Purpose: To determine the prevalence of central apnea (CA) events and central sleep apnea (CSA) in children with sleep-disordered breathing (SDB) and to assess the effect of tonsillectomy and adenoidectomy (TA) on CSA in children with obstructive sleep apnea (OSA). . The medical charts of children with SDB were reviewed to obtain information on past medical history, polysomnography (PSG) findings, and surgical management. Read More

Sleep Med 2022 Aug 5;96:99-104. Epub 2022 May 5.

Department of Otolaryngology-Head and Neck Surgery, Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Guangzhou, Guangdong Province, China. Electronic address:

Objective: Obstructive sleep apnea (OSA) may to be strongly associated with cancer mortality. The risk hazards of OSA regarding aggressive features of papillary thyroid carcinoma (PTC) remain unclear. The main objective of this study was to explore the relationship between OSA and aggressive features of PTC. Read More

Zhonghua Er Bi Yan Hou Tou Jing Wai Ke Za Zhi 2022 May;57(5):649-655

Department of Otorhinolaryngology Head and Neck Surgery, Xiangya Hospital, Central South University, National Clinical Research Center for Geriatric Diseases (Xiangya Hospital), Changsha 410008, China.

BMC Pulm Med 2022 May 24;22(1):204. Epub 2022 May 24.

Diagnostic Imaging Center, Kuopio University Hospital (KYS), P.O. Box 100, 70029, Kuopio, Finland.

Background: Obstructive sleep apnea (OSA) is associated with vascular diseases from which stroke and sudden cardiac death are the most significant ones. It is known that disturbances of the autonomic nervous system and electrocardiographic changes are seen in patients with a previous cerebrovascular event. However, the pathophysiological cascade between breathing cessations, autonomic regulation, and cardiovascular events is not fully understood. Read More