31 results match your criteria Centipede Envenomation

Centipede envenomation (Chilopoda): Case report.

Rev Soc Bras Med Trop 2022 6;55:e0601. Epub 2022 Jun 6.

Universidade Estadual Paulista, Instituto de Biociências, Botucatu, SP, Brasil.

Centipedes are venomous arthropods that have an elongated body, divided into many segments, presenting a pair of legs in each segment, adapted pairs of paws that simulate fangs and inject venom causing intense pain, with local erythema and edema, and rarely, blisters and skin necrosis. We present the case of a young woman pricked on her upper lip with intense swelling and local pain and discuss the real danger of envenomation and the therapeutic measures that should be taken. Read More

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Recombinant Production and Characterization of a New Toxin from Centipede Venom Revealed by Proteome and Transcriptome Analysis.

Toxins (Basel) 2021 12 2;13(12). Epub 2021 Dec 2.

Laboratório de Imunopatologia, Instituto Butantan, São Paulo 05503-900, Brazil.

Among the Chilopoda class of centipede, the genus is one of the most associated with envenomation in humans in the metropolitan region of the state of São Paulo. To date, there is no study in the literature about the toxins present in its venom. Thus, in this work, a transcriptomic characterization of the venom gland, as well as a proteomic analysis of its venom, were performed to obtain a toxin profile of this species. Read More

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December 2021

Mortality caused by venomous animals in Venezuela (2000-2009): A new epidemiological pattern

Biomedica 2021 03 19;41(1):29-40. Epub 2021 Mar 19.

Grupo de Investigación en Toxinología Aplicada y Animales Venenosos, Departamento de Ciencias Fisiológicas, Escuela de Ciencias de la Salud, Núcleo de Anzoátegui, Universidad de Oriente, Barcelona, Venezuela.

Introduction: Injuries by venomous animals frequently occur in impoverished communities with limited access to health services. They are considered neglected diseases that stand out as important causes of morbidity and mortality in various countries, including Venezuela. Objective: To assess mortalities resulting from contact with venomous animals in Venezuela from 2000 to 2009 (X20-X29 series). Read More

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An unusual two-stage infection following a scolopendra bite.

Acta Biomed 2020 12 30;91(14-S):e2020009. Epub 2020 Dec 30.

Orthopaedic and Trauma Department, Hospital Santa Maria delle Croci, Ravenna, Italy.

Background: Scolopendrae represent the best-known genus of centipedes. They are nocturnal general feeders with strong mandibles and venomous fangs which leave visible puncture marks at the bite site. The bite accidents occur during the warm rainy season and mostly take place on the extremities. Read More

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December 2020

Patients with centipede bites presenting to a university hospital in Bangkok: a 10-year retrospective study.

Clin Toxicol (Phila) 2021 Aug 21;59(8):721-726. Epub 2021 Jan 21.

Department of Emergency Medicine, Faculty of Medicine Vajira Hospital, Navamindradhiraj University, Dusit, Bangkok, Thailand.

Introduction: Centipede envenomation occurs commonly in tropical and subtropical countries. In most cases, centipede envenomation causes benign clinical manifestations. Serious complications are reported occasionally. Read More

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Toxicity of venom from the mamushi, Gloydius blomhoffii, (Squamata, Crotalinae) to centipedes.

Toxicon 2020 Dec 8;188:11-15. Epub 2020 Oct 8.

Department of Zoology, Graduate School of Science, Kyoto University, Sakyo, Kyoto, 606-8502, Japan.

Vipers include approximately 300 species and usually feed on vertebrates, but over 30 species of them occasionally eat centipedes. Centipedes have been also known to occur in stomach contents of a Japanese pit viper, mamushi, Gloydius blomhoffii. Toxicity of the venom of mamushi to small mammals has been well studied, but there is no information concerning its toxicity to arthropods. Read More

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December 2020

Target switch of centipede toxins for antagonistic switch.

Sci Adv 2020 08 7;6(32):eabb5734. Epub 2020 Aug 7.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of bioactive peptides of Yunnan Province, Kunming Institute of Zoology, Kunming, Yunnan 650223, China.

Animal venoms are powerful, highly evolved chemical weapons for defense and predation. While venoms are used mainly to lethally antagonize heterospecifics (individuals of a different species), nonlethal envenomation of conspecifics (individuals of the same species) is occasionally observed. Both the venom and target specifications underlying these two forms of envenomation are still poorly understood. Read More

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Complex regional pain syndrome following a centipede bite: a case report.

Clin Toxicol (Phila) 2020 07 26;58(7):777-779. Epub 2019 Nov 26.

Ramathibodi Poison Center, Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Complex Regional Pain Syndrome (CRPS) is a chronic neuropathic pain condition associated with autonomic features. To date, the development of CRPS following centipede bite has not been reported. We report a case of CRPS likely secondary to a centipede bite. Read More

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Challenges of Remote Medical Care in South Sudan: Centipede Bites.

Wilderness Environ Med 2019 Jun 19;30(2):203-207. Epub 2019 Apr 19.

Royal Army Medical Corps, Camberley, UK.

Centipede bites are a constant risk throughout tropical regions and have the rare potential for systemic side effects. We report a case of multiple centipede bites in South Sudan that was complicated by severe pain refractory to opioid analgesia and an unusual association with acute involuntary muscle contractions. Treatment with local anesthetic, antihistamines, and corticosteroids was effective. Read More

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The kiss of (cell) death: can venom-induced immune response contribute to dermal necrosis following arthropod envenomations?

Clin Toxicol (Phila) 2019 Aug 26;57(8):677-685. Epub 2019 Feb 26.

a Venom Systems and Proteomics Lab, School of Natural Sciences , Ryan Institute, National University of Ireland Galway , Galway , Ireland.

Snakes, insects, arachnids and myriapods have been linked to necrosis following envenomation. However, the pathways involved in arthropod venom-induced necrosis remain a highly controversial topic among toxinologists, clinicians and the public. On the one hand, clinicians report on alleged envenomations based on symptoms and the victims' information. Read More

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Centipede envenomation: Clinical importance and the underlying molecular mechanisms.

Toxicon 2018 Nov 29;154:60-68. Epub 2018 Sep 29.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences/Key Laboratory of Bioactive Peptides of Yunnan Province, Kunming Institute of Zoology, Kunming 650223, Yunnan, China. Electronic address:

Centipede bites are usually characterized by mildly to moderately painful encounters with humans, however, they are relatively infrequent. The vast majority of centipede envenomations do not cause severe symptoms and only in very rare cases more serious symptoms such as myocardial ischemia and infarction, hematuria, hemoglobinuria, rhabdomyolysis, hemorrhage, pruritus, eosinophilic cellulitis, as well as anaphylaxis are observed. More prevalent are symptoms including pain, paresthesia, lethargy, localized necrosis, headache, dizziness and nausea. Read More

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November 2018

Evaluation of Aristolochia indica L. and Piper nigrum L. methanol extract against centipede Scolopendra moristans L. using Wistar albino rats and screening of bioactive compounds by high pressure liquid chromatography: a polyherbal formulation.

Biomed Pharmacother 2018 Jan 28;97:1603-1612. Epub 2017 Nov 28.

Department of Pharmacy, Federal University of Sergipe, Cristovao, Sergipe, CEP, 49100-000, Sao Cristovao, Brazil.

The present study was aimed to explore the anti-venom activity of Aristolochia indica and Piper nigrum plants against the centipede (Scolopendra moristans) envenomation in animal model. In vtiro phytochemical, antioxidant and blocking of proteolysis were carried out by using standard spectrophotometric methods. In vivo anti-venom activity of methanol extracts was determined using Wistar albino rats after fixing lethal and effective doses. Read More

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January 2018

Vietnamese centipede envenomation.

Clin Toxicol (Phila) 2018 11 24;56(11):1168-1169. Epub 2018 Apr 24.

a Division of Emergency Medicine , Washington University School of Medicine , St. Louis , MO , USA.

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November 2018

Centipedes subdue giant prey by blocking KCNQ channels.

Proc Natl Acad Sci U S A 2018 02 22;115(7):1646-1651. Epub 2018 Jan 22.

Key Laboratory of Animal Models and Human Disease Mechanisms of Chinese Academy of Sciences, Kunming Institute of Zoology, Kunming 650223, Yunnan, China;

Centipedes can subdue giant prey by using venom, which is metabolically expensive to synthesize and thus used frugally through efficiently disrupting essential physiological systems. Here, we show that a centipede (, ∼3 g) can subdue a mouse (∼45 g) within 30 seconds. We found that this observation is largely due to a peptide toxin in the venom, SsTx, and further established that SsTx blocks KCNQ potassium channels to exert the lethal toxicity. Read More

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February 2018

Lymphangitis From Scolopendra heros Envenomation: The Texas Redheaded Centipede.

Wilderness Environ Med 2017 Mar 11;28(1):51-53. Epub 2017 Jan 11.

Department of Emergency Medicine, Texas A&M/Baylor Scott & White Health, Temple, TX (Drs Essler and Juergens).

Envenomation by Scolopendra heros, the Texas redheaded centipede, can present variably. Although transient pain and erythema are often treated conservatively, complications may include cellulitis, necrosis, myocardial infarction, and rhabdomyolysis. We present a case of an elderly man who came to the emergency department with lymphangitis and dermatitis secondary to a centipede sting that awoke him from sleep. Read More

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Venomous and poisonous arthropods: identification, clinical manifestations of envenomation, and treatments used in human injuries.

Rev Soc Bras Med Trop 2015 Nov-Dec;48(6):650-7

Clínica Privada, Ubatuba, São Paulo, Brazil.

This review presents the main species of venomous and poisonous arthropods, with commentary on the clinical manifestations provoked by the toxins and therapeutic measures used to treat human envenomations. The groups of arthopods discussed include the class Arachnida (spiders and scorpions, which are responsible for many injuries reported worldwide, including Brazil); the subphylum Myriapoda, with the classes Chilopoda and Diplopoda (centipedes and millipedes); and the subphylum Hexapoda, with the class Insecta and the orders Coleoptera (beetles), Hemiptera (stink bugs, giant water bugs, and cicadas), Hymenoptera (ants, wasps, and bees), and Lepidoptera (butterflies and moths). Read More

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Cardiovascular collapse after myocardial infarction due to centipede bite.

Wien Klin Wochenschr 2015 Jul 21;127(13-14):577-9. Epub 2015 May 21.

Department of Cardiology, Antalya Education and Research Hospital, Varlık mah. Kazımkarabekir Caddesi, Soğuksu, Muratpaşa, 07100, Antalya, Turkey.

Centipede bites have been reported to cause localized and/or systemic symptoms including local pain, erythema and edema, nausea and vomiting, palpitations, headache, lymphadenopathy, and rhabdomyolysis. However, acute myocardial infarction due to centipede envenomation is reported in only three cases in English medical literature.We present a case of 31-year-old male bitten by a golden colored centipede leading to myocardial infarction and cardiopulmonary arrest which is seen very rarely. Read More

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Centipede envenomation: bringing the pain to Hawai'i and Pacific Islands.

Hawaii J Med Public Health 2014 Nov;73(11 Suppl 2):41-3

Department of Medicine, Tripler Army Medical Center, Honolulu, HI 96859.

Scolopendra subspinipes is the only clinically significant centipede found in Hawai'i. Envenomation typically leads to extreme localized pain, erythema, induration, and tissue necrosis and possible lymphedema or lymphangitis. Mortality is uncommon and results from secondary infection or anaphylaxis. Read More

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November 2014

Local inflammatory reaction induced by Scolopendra viridicornis centipede venom in mice.

Toxicon 2013 Dec 17;76:239-46. Epub 2013 Oct 17.

Laboratory of Immunopathology, Butantan Institute, Av. Vital Brasil 1500, 05503-900 São Paulo, SP, Brazil.

Centipede envenomation is generally mild, and human victims usually manifest burning pain, erythema and edema. Despite the abundance and ubiquity of these animals, centipede venom has been poorly characterized in literature. For this reason, the aim of this work was to investigate local inflammatory features induced by Scolopendra viridicornis centipede envenomation in mice, evaluating edema formation, leukocyte infiltration, production of inflammatory mediators, and also performing histological analysis. Read More

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December 2013

Acute ST-segment elevation myocardial infarction from a centipede bite.

J Cardiovasc Dis Res 2011 Oct;2(4):244-6

Sri Gokulam Hospitals and Research Institute, Salem, Tamil Nadu, India.

Acute myocardial infarction (AMI) following a centipede bite has been very rarely reported. Here, we describe a 22 year-old man who had ST-segment elevation AMI after a centipede bite. He presented with typical chest pain, electro and echocardiographic abnormalities, and elevated cardiac enzymes with normal coronary angiography. Read More

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October 2011

Comparisons of ice packs, hot water immersion, and analgesia injection for the treatment of centipede envenomations in Taiwan.

Clin Toxicol (Phila) 2009 Aug;47(7):659-62

Department of Emergency Medicine, Chang-Gung Memorial Hospital, Kuei-Shang County, Taoyuan, Taiwan, Republic of China.

Objective: To compare the effectiveness of ice packs and hot water immersion for the treatment of centipede envenomations.

Methods: Sixty patients envenomated by centipedes were randomized into three groups and were treated with ice packs, hot water immersion, or analgesia injection. The visual analog score (VAS) for pain was measured before the treatment and 15 min afterward. Read More

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[Centipede bite in a woman with heterozygotous sickle cell disease].

Med Trop (Mars) 2008 Dec;68(6):647-8

Département d'Anesthésie-Réanimation-Urgences, Hôpital Principal, Dakar, Sénégal.

Although centipede bits can cause severe symptoms, they are seldom reported since outcome is generally favorable. The purpose of this report is to describe a case of centipede envenomation causing severe and prolonged symptoms in a woman with sickle cell trait. Read More

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December 2008

Toxic activities of Brazilian centipede venoms.

Toxicon 2008 Aug 4;52(2):255-63. Epub 2008 Jun 4.

Laboratory of Immunopathology, Butantan Institute, Av. Vital Brasil 1500, 05503-900, São Paulo, SP, Brazil.

Centipedes have a venom gland connected to a pair of forceps, which are used to arrest preys. Human victims bitten by centipedes usually manifest burning pain, paresthesia and edema, which may develop into superficial necrosis. The aim of this work was to characterize and compare toxic activities found in venoms of three species of Brazilian centipedes-Otostigmus pradoi, Cryptops iheringi and Scolopendra viridicornis. Read More

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[Centipede (Scolopendra sp.) envenomation in a rural village of semi-arid region from Falcon State, Venezuela].

Rev Invest Clin 2004 Nov-Dec;56(6):712-7

Posgrado de Medicina Interna, Hospital Universitario Alfredo Van Grieken, Coro, estado Falcón, Venezuela.

Introduction: Centipedes are invertebrate animals belonging to Phylum Arthropoda, Class Chilopoda, with a first pair of front legs that has been modified to form large, poisonous fangs connected to venomous glands. Likely, due to relatively benignity of the clinical manifestations, in Venezuela studies and research on centipede envenomation are virtually scarse.

Aim: The objective of this work was to study, biological, clinical, epidemiological and treatment profiles of envenomation caused by centipedes from Río Seco town, semi-arid area of Falcon State, Venezuelan north-western region. Read More

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Vietnamese centipede envenomation.

Vet Hum Toxicol 2004 Dec;46(6):312-3

Department Emergency Medicine, New York University, New York City Poison Control Center New York, New York 10016, USA.

The Vietnamese centipede (Scolopendra subspinipes) is one of the largest and most aggressive tropical centipedes. It has become a popular pet among arthropod enthusiasts and the general public. Despite their reputation, few well-documented cases of envenomation are reported in the medical literature. Read More

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December 2004

Acute coronary ischemia following centipede envenomation: case report and review of the literature.

Wilderness Environ Med 2004 ;15(2):109-12

Dokuz Eylul University School of Medicine, Department of Emergency Medicine, Inciralti, Izmir, Turkey.

This is the first known case report of electrocardiographic (ECG) changes suggestive of coronary vasospasm following a centipede envenomation. A 60-year-old man presented to the emergency department (ED) 1 hour after being stung by a 12-cm centipede. He complained of right great toe pain that did not radiate to his leg. Read More

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Centipede envenomation.

Wilderness Environ Med 2001 ;12(2):93-9

Department of Emergency Medicine, Loma Linda University School of Medicine, CA 92354, USA.

Five episodes of envenomation by centipedes in 2 patients are reported. These arthropods are fast-moving, frightening in appearance to some, and may display aggressive behavior. However, stings from these centipedes, like most found worldwide, caused no serious morbidity or mortality. Read More

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