Panton-Valentine Leukocidin Producing Staphylococcus aureus Facial Pyomyositis Causing Partial Cavernous Sinus Thrombosis.
- Katherine Green,
- Ioanna Chranioti,
- Saurabh Singh,
- Hans Rolf Jäger,
- Anje Drebes,
- Susie Gabbie,
- Jonathan Cohen
Pediatr Infect Dis J 2017 Jun 20. Epub 2017 Jun 20.
1Department of Paediatrics, Royal Free London NHS Foundation Trust, UK; 2Paediatric & Adolescent Division, University College Hospitals NHS Foundation Trust, UK, 3Centre of Medical Imaging, University College London, 4UCL Institute of Neurology Academic Neuroradiological Unit, University College London, UK; 5KD Haemophilia and Thrombosis Centre , Royal Free London NHS Foundation Trust, UK.
We present a case of sub-total cavernous sinus thrombosis secondary to Panton-Valentine leucocidin-associated Staphylococcus aureus pyomyositis of the muscles of mastication in a previously healthy child, who was successfully managed with no residual disease. He was found to have a factor V Leiden heterozygous mutation. We highlight the propensity of PVL-SA to induce venous thrombosis at any site, but with potential for more severe consequences in the head. Read More