Pediatr Infect Dis J 2017 Jun 20. Epub 2017 Jun 20.

1Department of Paediatrics, Royal Free London NHS Foundation Trust, UK; 2Paediatric & Adolescent Division, University College Hospitals NHS Foundation Trust, UK, 3Centre of Medical Imaging, University College London, 4UCL Institute of Neurology Academic Neuroradiological Unit, University College London, UK; 5KD Haemophilia and Thrombosis Centre , Royal Free London NHS Foundation Trust, UK.

We present a case of sub-total cavernous sinus thrombosis secondary to Panton-Valentine leucocidin-associated Staphylococcus aureus pyomyositis of the muscles of mastication in a previously healthy child, who was successfully managed with no residual disease. He was found to have a factor V Leiden heterozygous mutation. We highlight the propensity of PVL-SA to induce venous thrombosis at any site, but with potential for more severe consequences in the head. Read More

J Med Case Rep 2017 Jun 20;11(1):164. Epub 2017 Jun 20.

Eye Clinic, Melegnano Hospital, Vizzolo Predabissi, Milan, Italy.

Background: This case illustrates the importance of prompt assessment and treatment of orbital cellulitis. In fact the ocular signs and symptoms may be associated with systemic complications which should be investigated and identified as soon as possible to avoid a poor prognosis.

Case Presentation: A 46-year-old white woman presented to our emergency room with proptosis, ophthalmoplegia, and conjunctival chemosis of her left eye. Read More

Orbit 2017 Jun 3;36(3):135-136. Epub 2017 Mar 3.

a Ophthalmology Department , Mater Misericordiae University Hospital , Dublin , Ireland.

Orbital cellulitis is a serious sight threatening and potentially life threatening condition which can be complicated by orbital abscess formation. Posterior subtenon (PST) injection of corticosteroid is commonly used in the treatment of posterior segment inflammation including post-operative macular oedema. We report a case of orbital abscess formation as a late complication of PST triamcinolone acetonide and discuss the presentation, diagnosis and management. Read More

J Pediatric Infect Dis Soc 2017 Jun 1. Epub 2017 Jun 1.

Department of Pediatrics, Baylor College of Medicine and Texas Children's Hospital, Houston; and.

Background.: Periorbital and orbital cellulitis cause significant pediatric morbidity. Here, we define the clinical features of and characterize isolates from children with periorbital or orbital cellulitis caused by Staphylococcus aureus at Texas Children's Hospital in Houston. Read More

Saudi J Ophthalmol 2017 Apr-Jun;31(2):109-111. Epub 2017 Feb 21.

Department of Ocular Pathology, Dr. Rajendra Prasad Centre for Ophthalmic Sciences, All India Institute of Medical Sciences, Ansari Nagar, New Delhi 110029, India.

A previously diagnosed child of persistent hyperplastic primary vitreous (PHPV) with painless blind eye remained clinically silent for about 3 years follow-up. The child suddenly presented as a case of orbital cellulitis and panopthalmitis with meningitis. No definite mass lesion was detected on ultrasonography, magnetic resonance imaging (MRI) and positron emission tomography (PET) scan. Read More

J Glaucoma 2017 May 26. Epub 2017 May 26.

Sunderland Eye Infirmary, Sunderland, UK.

J Glaucoma 2017 May 26. Epub 2017 May 26.

Shri Ganesh Vinayak Eye Hospital, Raipur, India.

Ocul Immunol Inflamm 2017 May 24:1-3. Epub 2017 May 24.

a Department of Ophthalmology , University Hospital Centre Zagreb , Zagreb , Croatia.

Purpose: To present our experience in the management of superior ophthalmic vein thrombosis (SOVT), which is a rare, but extremely serious condition if not recognized and managed promptly and appropriately.

Methods: Two patients with septic and aseptic SOVT are presented. Clinical characteristics, radiographic features, management techniques, and outcomes are described. Read More

Vestn Oftalmol 2017 ;133(2):86-91

Research Institute of Eye Diseases, 11 A,B Rossolimo St., Moscow, Russian Federation, 119021; I.M. Sechenov First Moscow State Medical University, 2, str. 4 Bol'shaya Pirogovskaya St., Moscow, Russian Federation, 119991.

Granulomatous orbital cellulitis is one of the most common ocular manifestations of granulomatosis with polyangiitis (Wegener's). The process is often refractory to conventional immunosuppressive therapy and requires a more radical treatment approach. However, surgical experience with this type of patients is limited. Read More

J Vet Diagn Invest 2017 May 1:1040638717708584. Epub 2017 May 1.

Departments of Pathobiology and Population Medicine (Baumgartner), College of Veterinary Medicine, Mississippi State University, Mississippi State, MS.

In 2009, a virulent strain of Aeromonas hydrophila caused severe disease and high mortalities (motile aeromonad septicemia variant [MASv]) in farmed channel catfish ( Ictalurus punctatus) and hybrid catfish ( I. punctatus × I. furcatus) in eastern Mississippi and Alabama. Read More

Ophthal Plast Reconstr Surg 2017 May 5. Epub 2017 May 5.

*Division of Oculofacial Plastic and Reconstructive Surgery, UC San Diego Department of Ophthalmology, Shiley Eye Institute, La Jolla, California, †Division of Oculofacial Plastic and Reconstructive Surgery, University of Miami Bascom Palmer Eye Institute, Miami, Florida, ‡Division of Radiology, Rady Children's Hospital, San Diego, California, and §Division of Plastic Surgery, University of California San Diego Division of Plastic Surgery, La Jolla, California, U.S.A.

An 11-year-old female presented with orbital cellulitis, bacterial sinusitis, enlarged left superior ophthalmic vein, dural venous sinuses, and internal jugular vein. The patient underwent endoscopic sinus surgery and was started on intravenous antibiotics and anticoagulation with limited improvement in orbital signs and symptoms. A magnetic resonance imaging/magnetic resonance venography of the orbits and brain revealed a dilated left superior ophthalmic vein with absence of flow but no clearly discernible orbital abscess. Read More

BMJ Case Rep 2017 Apr 28;2017. Epub 2017 Apr 28.

Division of Infectious Diseases, Department of Internal Medicine, American University of Beirut, Beirut, Lebanon.

A middle-aged poorly controlled diabetic man developed left-sided orbital and facial swelling several days after extraction of a left upper wisdom tooth. The clinical impression was that of acute dacryocystitis. Opening the skin above the lacrimal sac failed to reveal an inflamed sac establishing the diagnosis of deep facial cellulitis. Read More

Am J Ther 2017 Apr 25. Epub 2017 Apr 25.

1Division of Pediatric Emergency Medicine, Department of Pediatrics, Dana-Dwek Children Hospital, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel; 2Divisions of Pediatric Emergency Medicine and Clinical Pharmacology and Toxicology, Department of Pediatrics, The Hospital for Sick Children, University of Toronto, Canada; and 3Division of Pediatrics, Dana-Dwek Children Hospital, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.

Introduction: Preseptal (periorbital) and orbital cellulitis are potentially catastrophic infections near the eye. Preseptal cellulitis is far more common, and although classically reported to be associated with dacrocystitis, sinusitis/upper respiratory infection, trauma/surgery, or infection from contiguous areas, it can also be associated with insect bites. The objective of this study was to determine the prevalence of insect bite-associated preseptal cellulitis and to compare clinical findings and outcomes of these patients with those having other causes for the condition. Read More

Radiologia 2017 May - Jun;59(3):182-195. Epub 2017 Apr 10.

Hospital Universitario Puerta de Hierro-Majadahonda, Majadahonda, Madrid, España.

Nontraumatic emergencies of the head and neck represent a challenge in the field of neuroradiology for two reasons. As explained in the first part of this update, these entities affect an area where the thorax joins the cranial cavity and can thus compromise both structures; second, they are uncommon, so they are not well known. Maintaining the same approach as in the first part, focusing on the clinical presentations in the emergency department rather than on the anatomic regions affected, we will study the entities that present with two patterns: those that present with a combination of cervical numbness, dysphagia, and dyspnea and those that present with acute sensory deficits. Read More

Open Ophthalmol J 2017 31;11:11-16. Epub 2017 Jan 31.

Department of Ophthalmology, The George Washington University, Washington D.C., USA.

Purpose: To determine whether prophylactic antibiotic use in patients with orbital fracture prevent orbital infection.

Design: Retrospective cohort study.

Participants: All patients diagnosed with orbital fracture between January 1, 2008 and March 1, 2014 at The George Washington University Hospital and Clinics. Read More

Int J Pediatr Otorhinolaryngol 2017 May 6;96:72-76. Epub 2017 Mar 6.

Department of Otolaryngology, Sant'Orsola-Malpighi Hospital, University of Bologna, Via Massarenti 9, 40138 Bologna, Italy. Electronic address:

Objective: Pediatric periorbital cellulitis represents a common disease complicating a nasal infection.

Methods: A ten-year retrospective review of fifty-seven children admitted to our institution with the diagnosis of periorbital cellulitis as a complication of sinus infections was carried out.

Results: The age varied from one month to eleven years (mean 3. Read More

Ophthal Plast Reconstr Surg 2017 Mar 31. Epub 2017 Mar 31.

Department of Ophthalmology, SUNY Downstate Medical Center, Brooklyn, New York, U.S.A.

Purpose: To compare the outcomes of children with orbital cellulitis treated with intravenous (IV) dexamethasone and antibiotics on admission to patients treated with antibiotics alone.

Methods: Prospective comparative interventional study. Forty-three children admitted to a tertiary institution with orbital cellulitis were enrolled. Read More

Oral Maxillofac Surg 2017 Jun 16;21(2):271-279. Epub 2017 Mar 16.

Department of Surgery, Section of Oral and Maxillofacial Surgery, University of Verona, Verona, Italy.

Odontogenic orbital abscess is a rare but well-documented complication of sinusitis and infections spreading from dental apical lesion. We report a case of orbital abscess with periorbital cellulitis, in a 35-year-old man with positive recent dental history of a periapical dental infection arising from the second upper left premolar spread into maxillary sinus. The patient has shown facial edema, ocular pain, ophthalmoplegia, proptosis, and initial visual symptoms. Read More

Surv Ophthalmol 2017 Mar 11. Epub 2017 Mar 11.

Department of Pathology, Duke University Medical Center, Durham, North Carolina, USA. Electronic address:

Periocular necrotizing fasciitis developed in a 12-month-old boy with swelling of both eyes and redness and a discharge from the left eye approximately 36 hours after blunt trauma. Computed tomography revealed preseptal and soft-tissue edema on the left side, but no signs of orbital involvement, orbital fractures, or drainable abscess in the anterior left lower eyelid. The inflammatory signs worsened over the next day, and there was purulent discharge from the left lower eyelid and an abscess and necrosis of the lower eyelid skin. Read More

Pan Afr Med J 2016 2;25:131. Epub 2016 Nov 2.

Ophthalmology Department, Mohamed VI University Hospital, Marrakech, Morroco.

Retinoblastoma is the most frequent childhood intraocular tumor. The aim of our study is to evaluate the clinical features and management of extra-ocular retinoblastoma in the Mohamed VI university hospital of Marrakech. Retrospective case series, the patient's records were reviewed for patient and tumor features, ocular management, histopathological findings, and patient survival. Read More

Mil Med 2017 Mar;182(3):e1880-e1882

Department of Dermatology, Naval Health Clinic Hawaii, 480 Central Avenue, Pearl Harbor, HI 96869.

Introduction: Psoriatic patients on tumor necrosis factor alpha inhibitors (TNFi) may be at increased risk for upper respiratory tract infections, including chronic rhino-sinusitis (CRS). Rarely, CRS can progress to orbital cellulitis (OC), an emergent ophthalmic complication wherein respiratory flora from paranasal sinus disease intrude the retro-orbital space.

Materials And Methods: Single case report. Read More

J Emerg Med 2017 Jun 9;52(6):e221-e223. Epub 2017 Mar 9.

Department of Internal Medicine, University Hospitals Leuven, Leuven, Belgium.

Background: Endophthalmitis is a feared complication of pyogenic liver abscesses caused by hypervirulent Klebsiella pneumoniae strains. First described in East Asia in the 1980s, this invasive syndrome is only recently emerging in Europe and America.

Case Report: We describe an 84-year-old man who presented to the emergency department with fever, orbital cellulitis, and bilateral visual loss. Read More

J Ophthalmic Inflamm Infect 2017 Dec 9;7(1). Epub 2017 Mar 9.

Department of Ophthalmology, Minia University Hospital, Minia City, Minia Governorate, Egypt.

Background: The purpose of this paper is to study the etiology, clinical findings, and outcomes of management of cases of orbital cellulitis treated in Minia University Hospital in Upper Egypt over the period of 6 years from July 2009 to July 2015. One-hundred two patients diagnosed to have orbital cellulitis were admitted to the hospital and treated on inpatient basis from July 2009 to July 2015. All patients were subjected to full ophthalmological examination, systemic evaluation, and ear, nose, and throat (ENT) consultation. Read More

Surv Ophthalmol 2017 Feb 27. Epub 2017 Feb 27.

Department of Pathology, Ankara University Faculty of Medicine, Ankara, Turkey.

Orbital cellulitis associated with retinoblastoma is uncommon and is characterised by non-infectious inflammation of the periorbital structures. The underlying mechanism is thought to be necrosis of the intraocular tumor leading to intraocular and periorbital inflammation. We report two retinoblastoma patients who presented with an orbital cellulitis-like picture. Read More

J Clin Diagn Res 2016 Dec 1;10(12):MC04-MC07. Epub 2016 Dec 1.

Residents, Department of ENT, Krishna Institute of Medical Sciences University , Karad, Maharashtra, India .

Introduction: The use of corticosteroids or antihistaminics in treatment of allergic rhinitis is known and practiced since long. The efficacy of topical use of fluticasone propionate and Olopatadine Hydrochloride (HCL) for symptomatic relief of allergic rhinitis has been studied either individually or with other drugs. But very few studies show comparison between these two drugs. Read More

GMS Ophthalmol Cases 2017 6;7:Doc04. Epub 2017 Feb 6.

Pathology Department, Hospital Sultanah Aminah Johor Bahru, Johor, Malaysia.

Objective: To report an aggressive case of extranodal natural killer/T-cell lymphoma (NKTCL) of the ethmoid sinus presenting as orbital cellulitis Method: Case report Results: A 56-year-old male presented with right eye redness, reduced vision, and periorbital swelling for 5 weeks duration associated with a two-month history of blocked nose. The visual acuity of the right eye was 6/18. The eye was proptosed with periorbital oedema and conjunctival chemosis. Read More

Clin Exp Ophthalmol 2017 Feb 10. Epub 2017 Feb 10.

South Australian Institute of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Austalia, Australia.

Clin Neuroradiol 2017 Feb 9. Epub 2017 Feb 9.

Department of Neuroradiology, University Hospital Zurich, Frauenklinikstrasse 10, 8091, Zurich, Switzerland.

Am J Hematol 2017 Jun 4;92(6):591-592. Epub 2017 Mar 4.

Department of Internal Medicine, Plaza Medical Center, Dallas, Texas, USA.

J Glaucoma 2017 Feb;26(2):e101-e102

Sunderland Eye Infirmary, Sunderland, Tyne and Wear.

Purpose: To date, there have only been 5 reported cases of orbital cellulitis following implantation of an aqueous tube shunt for glaucoma. Previously reported cases have involved eyes with significant comorbidities and successful management has often required the removal of the device alongside systemic antibiotic therapy.

Patients And Methods: We present a 53-year-old man with severe orbital cellulitis, 3 months after routine implantation of a Baerveldt tube shunt for primary open angle glaucoma. Read More

Am J Respir Crit Care Med 2017 Feb;195(4):533-535

SUNY Downstate Medical Center, Brooklyn, New York.

Korean J Ophthalmol 2016 Dec 6;30(6):483-484. Epub 2016 Dec 6.

Royal Victorian Eye and Ear Hospital, Melbourne, Australia.

Am J Case Rep 2016 Dec 9;17:934-938. Epub 2016 Dec 9.

Department of Otolaryngology, Hamad Medical Corporation, Doha, Qatar.

BACKGROUND Extranodal lymphoma of the paranasal sinuses is a rare clinical entity seen in only 5-8% of extranodal lymphomas of the head and neck. Nasal natural killer/T cell lymphoma (Nasal NKTCL), which is a subtype of peripheral T cell lymphoma, constitutes about 1.4% of all lymphomas. Read More

Am J Otolaryngol 2017 Mar - Apr;38(2):130-134. Epub 2016 Nov 24.

Department of Ophthalmology, Academic Medical Center Amsterdam, The Netherlands.

Background: Pre- or retroseptal bacterial orbital cellulitis (pOC/rOC) is not an uncommon orbital disease. Treatment consists of antibiotics with or without surgical drainage. Several questions regarding course, complications and outcome of treatment are unanswered and the indication for surgery is not well defined. Read More

Indian Pediatr 2016 Nov;53(11):1037

Pediatric Hematology-Oncology unit, Department of Pediatrics, Advanced Pediatrics Center, and # Department of Ophthalmology, PGIMER, Chandigarh, India.

Dis Mon 2017 Feb 22;63(2):30-32. Epub 2016 Nov 22.

Ophthal Plast Reconstr Surg 2016 Nov 22. Epub 2016 Nov 22.

*King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia; †Department of Ophthalmology, Complejo Hospitalario Palencia, Palencia, Spain; ‡Department of Ophthalmology, College of Medicine, King Saud University, Riyadh, Saudi Arabia; §Department of Diagnostic Radiology, Mansoura Faculty of Medicine, Mansoura, Egypt; and ‖Department of Ophthalmology, Otorhinolaryngology and Head and Neck Surgery, School of Medicine of Ribeirão Preto - University of São Paulo, São Paulo, Brazil.

An 8-year-old boy initially presented with an orbitopalpebral mass diagnosed clinically and radiologically as a low-flow diffuse venous lymphatic malformation involving the left upper eyelid and orbit. Over 8 months of follow up, he had 2 acute episodes of severe orbital inflammation that warranted hospitalization and treatment with intravenous antibiotic, steroids and surgical debulking. After a third surgical excision, the lesion remained clinically stable. Read More

Ulus Travma Acil Cerrahi Derg 2016 Sep;22(5):432-436

Department of Ophthalmology, Uludağ University Faculty of Medicine, Bursa-Turkey.

Background: The present study is an evaluation of clinical features and management outcomes of patients operated on for intraorbital foreign bodies (FBs).

Methods: Medical records of 24 patients who underwent surgery for intraorbital FBs within a 10-year period were reviewed.

Results: Twenty patients (83%) were male and 4 (17%) were female (mean age: 28 years; range: 4-69 years). Read More

Niger J Surg 2016 Jul-Dec;22(2):107-110

Department of Ophthalmology, University of Benin Teaching Hospital, P.M.B. 1111, Benin, Edo State, Nigeria.

Background: Orbital cellulitis refers to the inflammation or infection of the soft tissues of the orbit located behind the orbital septum.

Aim: To determine the current trends in the outcomes following the management of orbital cellulitis in a tertiary hospital in Southern Nigeria.

Patients And Methods: A retrospective review of medical records of patients with orbital cellulitis from January 2008 to December 2014 was conducted. Read More

Clin Ophthalmol 2016 27;10:2129-2133. Epub 2016 Oct 27.

Department of Ophthalmology, Lewis Katz School of Medicine; Department of Bioengineering, College of Engineering, Temple University, Philadelphia, PA, USA.

Purpose: The purpose of this study was to analyze the practice management patterns of the current members of the American Society of Ophthalmic Plastic and Reconstructive Surgery (ASOPRS) and to determine the use of oral prophylactic antibiotics in an attempt to prevent orbital cellulitis following nonoperative orbital fractures.

Patients And Methods: A cross-sectional web-based survey was emailed to all the members of ASOPRS regarding their current management of nonsurgical orbital fractures and their experience with orbital cellulitis following nonoperative orbital fractures.

Results: The majority of practicing oculoplastic surgeon members of ASOPRS do not routinely prescribe prophylactic antibiotics for patients with nonoperative orbital fractures or patients with orbital fractures whom the physicians are observing and who might potentially need surgical intervention. Read More

J AAPOS 2016 Dec 31;20(6):546-548.e2. Epub 2016 Oct 31.

Moorfields Eye Hospital NHS Foundation Trust, London, England; UCSF Benioff Children's Hospital, UCSF Medical Center (Mission Bay), San Francisco, California.

Ophthalmomyiasis interna posterior is a rare condition caused by the invasion of the ocular posterior segment by the larval form of certain flies in the order Diptera. The main clinical features are reduced visual acuity, intense posterior uveitis, and neuroretinitis. Treatment of this condition is predominantly surgical, including argon laser photocoagulation for subretinal larva and pars plana vitrectomy for intravitreal infection. Read More

J AAPOS 2016 Dec 31;20(6):527-531.e1. Epub 2016 Oct 31.

Vanderbilt Eye Institute, Vanderbilt University School of Medicine, Nashville, Tennessee. Electronic address:

Purpose: To investigate practice patterns for cases of subperiosteal abscess (SPA) with concomitant frontal sinusitis to identify factors favorable to medical management in children <9 years of age.

Methods: The medical records of all pediatric cases of orbital and periorbital cellulitis admitted at a tertiary care center from 1999-2014 were reviewed retrospectively. Cases were included if radiography demonstrated sinusitis-associated SPA in children <9 years of age. Read More

Case Rep Ophthalmol Med 2016 10;2016:9630698. Epub 2016 Oct 10.

Ruiz Department of Ophthalmology and Visual Science, The University of Texas Health Science Center at Houston, Houston, TX, USA; Robert Cizik Eye Clinic, Houston, TX, USA.

We present a case of a 50-year-old woman with acute dacryocystitis that was complicated by posterior rupture of the lacrimal sac causing an orbital cellulitis with subsequent visual acuity of no light perception. Upon presentation, she was immediately started on broad-spectrum antibiotics and underwent surgical incision and drainage of the lacrimal sac abscess but never regained vision. There are 4 cases in the literature of permanent severe vision loss from acute dacryocystitis. Read More

Acta Paediatr 2017 Feb 24;106(2):268-273. Epub 2016 Nov 24.

Sach's Children and Youth Hospital, South General Hospital, Stockholm, Sweden.

Aim: This study established the incidence of acute rhinosinusitis and related orbital complications in tertiary care in Stockholm County and surveyed the clinical outcomes.

Methods: This was a population-based, retrospective, observational study, from July 1, 2003 to June 30, 2007, of the hospital admissions records of 213 children up to five years old, with a diagnosis of sinusitis and related complications.

Results: Preseptal cellulitis was present in 171 of the 213 admissions, which equated to an incidence of orbital complications due to acute rhinosinusitis of 36 per 100 000 people per year (95% confidence interval 26-49). Read More

Jpn J Infect Dis 2017 May 31;70(3):314-316. Epub 2016 Oct 31.

Department of Ophthalmology, Lokmanya Tilak Municipal Medical College & General Hospital Sion.

Orbital cellulitis along with panophthalmitis is uncommon. The causes are usually trauma-related or endogenous. The prognosis in terms of globe salvage is very poor, with most cases usually requiring enucleation or evisceration of the affected eye. Read More

Eur J Ophthalmol 2016 Oct 13;27(1). Epub 2016 Oct 13.

Department of Ophthalmology, Eye and Ear Institute, University of Pittsburgh Medical Center, Pittsburgh, PA - USA.

Purpose: To report a case of bilateral cavernous sinus thrombosis (CST) in a patient with tacrolimus-associated posttransplant thrombotic microangiopathy.

Methods: Case report.

Results: An 8-year-old boy with a medical history of orthotopic heart transplant, posttransplant lymphoproliferative disease, and recurrent infections was hospitalized for nausea, vomiting, and diarrhea. Read More

J Emerg Med 2017 Feb 14;52(2):e41-e43. Epub 2016 Oct 14.

Department of Neurosurgery, Rush University Medical Center, Chicago, Illinois.

Indian J Ophthalmol 2016 Aug;64(8):609-11

Department of Ophthalmology, Government Medical College and Hospital, Chandigarh, India.

Orbital cellulitis is an infection of soft tissue behind the orbital septum. Common pathogens isolated include Staphylococcus aureus, Staphylococcus epidermidis, and Streptococcus pneumoniae. It is a straightforward diagnosis and usually responds to empirical treatment without any sequela. Read More

BMC Ophthalmol 2016 Sep 21;16(1):165. Epub 2016 Sep 21.

Department of Anatomy, All India Institute of Medical Sciences, Ansari Nagar, New Delhi, 110029, India.

Background: Discovery of sessile mode of microbial existence (Biofilm state) focussed much interest, during the recent years, on the study of biofilms in many recurring and chronic infections. However, the exact role of microbial biofilms in chronic rhinosinusitis and orbital cellulitis were not elucidated earlier. The purpose of the present study was to look for the adherent property and biofilm producing ability of the clinical isolates in chronic rhinosinusitis and orbital cellulitis, and to look for the effects of antimicrobial agents on these biofilms by colorimetric assay and ultrastructural analysis. Read More

Balkan Med J 2016 Jul 1;33(4):401-6. Epub 2016 Jul 1.

Department of Otorhinolaryngology, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China; Institute of Eye and ENT, Shandong Provincial Hospital Affiliated to Shandong University, Jinan, China.

Background: The orbital complications account for about 80% of all complications secondary to acute rhinosinusitis. If the treatment is not correct and in time, orbital complications could progress rapidly, leading to optic neuritis, cavernous sinus thrombophlebitis or life-threatening intracranial complications.

Aims: To evaluate the therapeutic efficacy of conservative therapy for the patients with orbital cellulitis and endoscopic sinus surgery (ESS) performed on patients with subperiosteal abscess (SPA) secondary to acute rhinosinusitis in children. Read More