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    Vancomycin Infiltrate-Induced Dermatitis Mimicking Bullous Cellulitis.
    J Drugs Dermatol 2017 Nov;16(11):1160-1163

    Extravasation of medications can manifest as tenderness, pain, tissue necrosis, and thrombophlebitis and lead to infection and severe long-term complications. Risk factors for leakage of medications include mechanical and pharmacologic mechanisms such as cannulation technique, vasoconstriction, and cytotoxicity. Well-known vesicants like anthracyclines, vinca alkaloids, and vasopressors are usually administered with proper caution. Read More

    Two Cases of Lepromatous Leprosy from Exposure to Armadillos in Florida.
    Skinmed 2017 1;15(5):391-393. Epub 2017 Oct 1.
    Department of Dermatopathology, James A. Haley Veterans Hospital, Tampa, FL.
    The first patient was a 41-year-old white man who was referred to the dermatology clinic with a 2-year history of numerous erythematous, hypoesthetic, poorly demarcated papules and plaques present on the trunk, buttocks, and bilateral upper and lower extremities (Figures 1 and 2). The lesions had initially begun as localized erythematous plaques on the right flank, and were diagnosed and treated as cellulitis and allergic contact dermatitis by primary care on separate occasions, with no resolution and continued gradual but persistent spread. Read More

    Lymphedema: Diagnostic workup and management.
    J Am Acad Dermatol 2017 Dec;77(6):995-1006
    Department of Dermatology, Boston University School of Medicine, Boston, Massachusetts.
    Lymphedema is a localized form of tissue swelling resulting from excessive retention of lymphatic fluid in the interstitial compartment. It is caused by impaired lymphatic drainage. Lymphedema is a chronic progressive disease with serious physical and psychosocial implications. Read More

    When an Orbital Infection Isn't Infectious at All: A Review of Orbital Inflammatory Syndrome.
    Pediatr Ann 2017 Nov;46(11):e433-e436
    Orbital inflammatory syndrome (OIS) includes a wide range of clinical manifestations and may initially be misdiagnosed as orbital cellulitis due similar symptoms of fever, periorbital swelling, and pain with eye movements. A diagnosis of OIS requires evaluation for underlying systemic disorders including autoimmune disorders and thyroid disease. Symptoms typically improve rapidly after initiation of steroid therapy, although recurrence can occur. Read More

    A Comparison of Laboratory Testing in Teaching vs Nonteaching Hospitals for 2 Common Medical Conditions.
    JAMA Intern Med 2017 Nov 13. Epub 2017 Nov 13.
    Department of Internal Medicine, Dell Medical School at The University of Texas at Austin.
    Importance: Robust laboratory use data are lacking to support the general assumption that teaching hospitals with trainees routinely order more laboratory tests for inpatients than do nonteaching hospitals.

    Objective: To quantify differences in the use of laboratory tests between teaching and nonteaching hospitals.

    Design, Setting, And Participants: A cross-sectional study was performed using a statewide database to identify hospitalizations with a primary diagnosis of bacterial pneumonia or cellulitis from January 1, 2014, to June 30, 2015, at teaching and nonteaching hospitals with 100 or more hospitalizations of each condition. Read More

    Interhemispheric and Infratentorial Subdural Empyema with Preseptal Cellulitis as Complications of Sinusitis: A Case Report.
    Pediatr Neurosurg 2017 Nov 11. Epub 2017 Nov 11.
    Department of Neurosurgery, Kanudjoso Djatiwibowo Hospital, Balikpapan, Indonesia.
    Intracranial complications of paranasal sinusitis have become rare due to the use of antibiotics nowadays. However, several cases have been reported due the ability of paranasal sinusitis to cause serious complications. Once the infection spreads over the cranial structure, it could infect the orbits, underlying bones, meninges, adjacent veins, and brain. Read More

    [Maternal deaths due to anesthesia complications. Results from the French confidential enquiry into maternal deaths, 2010-2012].
    Gynecol Obstet Fertil Senol 2017 Nov 6. Epub 2017 Nov 6.
    Département d'anesthésie-réanimation, hôpital femme-mère-enfant, hospices civils de Lyon, 59, boulevard Pinel, 69500 Bron, France. Electronic address:
    Over the period 2010-2012, maternal mortality linked to anesthesia accounted for 2% of maternal deaths, with no significant change since 2007-2009. Of the 7 maternal deaths analyzed by the expert committee, anesthetic complications were in 5 cases the main cause of death: 4 attributed to direct causes related to anesthetic procedures during childbirth and 1 to indirect cause in connection with an ENT complication during pregnancy. The anesthetic causes of maternal mortality were for the 2010-2012 period: cardiac arrest under spinal anesthesia during caesarean section, local anesthetic intoxication with unsuccessful resuscitation after cardiac arrest without intralipid administration, acute respiratory distress syndrome in the postpartum period after pulmonary aspiration during caesarean section, cardiac arrest during caesarean section under general anesthesia in a context of non-Hodgkin lymphoma with mediastinal syndrome, unsuccessful endotracheal intubation in a context of cellulitis of the oral cavity floor. Read More

    A review of squamous cell vulvar cancers in Waikato region, New Zealand.
    N Z Med J 2017 Nov 10;130(1465):19-28. Epub 2017 Nov 10.
    Medical Oncologist, Lomas Building, Waikato Hospital, Pembroke Street, Hamilton.
    Background: Squamous cell vulvar cancers (SCVC) are rare. Although management guidelines have recently been published, New Zealand studies presenting "real world" outcomes are limited.

    Methods: Retrospective single-centre review of SCVC diagnosed between 1 January 2000 and 31 August 2015. Read More

    Managing chronic oedema and wet legs in the community: a service evaluation.
    Nurs Stand 2017 Nov;32(11):39-50
    Lymphoedema Network Wales, Cimla Hospital, West Glamorgan, Wales.
    Patients with chronic oedema and 'wet legs' are frequently seen in the community setting, with research indicating that more than half of community nurses' caseloads are patients with chronic oedema. However, a lack of nurse education and standardised care pathways for this condition has been identified. In June 2016, the Welsh Government supported the development of the On the Ground Education Project (OGEP), which aimed to raise community nurses' awareness and recognition of chronic oedema and wet legs, to improve the management of these conditions, and to support the efficient use of community nurses' time and resources. Read More

    Dissecting Cellulitis of the Scalp Early Diagnosed by Color Doppler Ultrasound.
    Int J Trichology 2017 Oct-Dec;9(4):147-148
    Department of Dermatology, Faculty of Medicine, Pontifical Catholic University, Santiago, Chile.
    Dissecting cellulitis of the scalp (DC) is a chronic inflammatory condition of the scalp that ultimately leads to scarring alopecia. A healthy 19-year-old male presented with a solitary, soft, alopecic nodule that had appeared 1 year before. A color Doppler ultrasound examination showed a hypodermal anechoic fluid collection in the left parietotemporal region of the scalp, connected to the base of widened hair follicles, and presented inner echoes suggestive of debris, as well as several fragments of hair tracts. Read More

    Patterns of paediatric emergency presentations to a tertiary referral centre in the Northern Territory.
    Emerg Med Australas 2017 Nov 8. Epub 2017 Nov 8.
    Emergency Department, The Royal Children's Hospital, Melbourne, Victoria, Australia.
    Objective: To describe epidemiological data concerning paediatric attendances at the ED of Royal Darwin Hospital (RDH).

    Methods: We conducted a retrospective cohort study of paediatric emergency presentations to the RDH ED during 2004 and 2013. Epidemiological data, including demographics, admission rates and diagnostic grouping, were analysed using descriptive and comparative statistical methods. Read More

    Point-of-Care Ultrasound is Associated With Decreased Length of Stay in Children Presenting to the Emergency Department With Soft Tissue Infection.
    J Emerg Med 2017 Oct 27. Epub 2017 Oct 27.
    Division of Emergency Medicine, Boston Children's Hospital, Boston, Massachusetts.
    Background: Point-of-care ultrasound (POCUS) is increasingly being used to differentiate cellulitis from abscess in the pediatric emergency department (ED). POCUS has also been shown to decrease length of stay (LOS) for other applications among adult patients.

    Objective: We sought to determine if ED LOS differed for children presenting with skin and soft tissue infections who received POCUS versus radiology-performed ultrasound. Read More

    Post-irradiation morphoea of the breast: a case report and review of the literature.
    Histopathology 2017 Aug 14. Epub 2017 Aug 14.
    Breast Cancer Research Program, Vanderbilt-Ingram Cancer Center, Vanderbilt University Medical Center, Nashville, TN, USA.
    We describe a 44-year-old female with triple-negative breast cancer who developed skin erythaema, sclerosis and contracture of her entire right breast 15 months after completion of post-lumpectomy chemotherapy and radiotherapy, consistent with post-irradiation morphoea (PIM). PIM is a rare complication of breast irradiation that impairs a patient's quality of life. PIM is located usually at the radiation port or in the surrounding tissue. Read More

    Ludwig's angina in children anesthesiologist's nightmare: Case series and review of literature.
    J Anaesthesiol Clin Pharmacol 2017 Jul-Sep;33(3):406-409
    Department of Anaesthesia and Intensive Care, Lady Hardinge Medical College, New Delhi, India.
    Ludwig's angina is potentially lethal, rapidly spreading cellulitis of the floor of mouth and neck. The anticipated difficult airway becomes even more challenging when it occurs in children. In children, the larynx is positioned relatively higher in the neck, and one does not have the option for blind nasal intubation or awake fiberoptic, which otherwise is the technique of choice in adult patients. Read More

    [Maternal deaths due to infectious cause, results from the French confidential enquiry into maternal deaths, 2010-2012].
    Gynecol Obstet Fertil Senol 2017 Nov 3. Epub 2017 Nov 3.
    Service d'anesthésie-réanimation, hôpital Nord, AP-HM, chemin des Bourrely, 13015 Marseille, France.
    Over the period 2010-2012, maternal mortality from infectious causes accounted for 5% of maternal deaths by direct causes and 16% of maternal deaths by indirect causes. Among the 22 deaths caused by infection occurred during this period, 6 deaths were attributed to direct causes from genital tract origin, confirming thus the decrease in direct maternal deaths by infection during the last ten years. On the contrary, indirect maternal deaths by infection, from extragenital origin, doubled during the same period, with 16 deaths in the last triennium, dominated by winter respiratory infections, particularly influenza: the 2009-2010 influenza A (H1N1) virus pandemic was the leading cause of indirect maternal mortality by infection during the studied period. Read More

    Epidemiology of primary ophthalmic inpatient admissions in the United States.
    Am J Ophthalmol 2017 Oct 31. Epub 2017 Oct 31.
    Wilmer Eye Institute, Johns Hopkins School of Medicine, Baltimore, MD. Electronic address:
    Purpose: To determine the national estimates, demographics and costs of inpatient eye care in the United States (US).

    Design: Retrospective cross-sectional study.

    Methods: National Inpatient Sample (NIS), a representative sample of all US community hospitals, was used to analyze inpatient admissions with a primary ophthalmic diagnosis from 2001 to 2014. Read More

    Flap coverage for the treatment of exposed left ventricular assist device (LVAD) hardware and intractable LVAD infections.
    J Card Surg 2017 Nov 3. Epub 2017 Nov 3.
    Hansjörg Wyss Department of Plastic Surgery, NYU Langone Medical Center, New York, New York.
    Background: Left ventricular assist devices (LVADs) have become useful adjuncts in the treatment of patients with end-stage heart failure. LVAD implantation is associated with a unique set of problems; one such problem is device infection. We report our experience with flap salvage of infected and/or exposed LVAD hardware. Read More

    A Case of Daptomycin-induced Eosinophilic Pneumonia and a Review of the Published Literature.
    Intern Med 2017 Nov 1. Epub 2017 Nov 1.
    Department of Clinical Infectious Diseases, Graduate School of Medicine and Pharmaceutical Sciences for Research, University of Toyama, Japan.
    A 53-year-old man was admitted to the hospital with a diagnosis of cellulitis and osteomyelitis. Twenty-four days after the initiation of daptomycin and sulbactam/ampicillin, he developed a fever and pulmonary infiltration. Bronchoalveolar lavage revealed a high number of eosinophils, while an intracutaneous test revealed positivity for daptomycin. Read More

    Soft-tissue infection secondary to cellulitis killed St. John of the Cross (1542-1591).
    Infection 2017 Oct 31. Epub 2017 Oct 31.
    Department of Medicine, "San Giovanni di Dio" Hospital, Gorizia, Italy.
    Purpose: St. John of the Cross (1542-1591) died aged 49 years after 3 months of excruciating pain following a trivial lesion in his right foot. Erysipelas, a superficial bacterial infection of the skin, and subsequent sepsis were previously suggested as the cause of his death. Read More

    Clinical Presentation of Soft-tissue Infections and its Management: A Study of 100 Cases.
    Niger J Surg 2017 Jul-Dec;23(2):86-91
    Department of Surgery, Government Medical College, Amritsar, Punjab, India.
    Background: Soft-tissue infections vary widely in their nature and severity. A clear approach to the management must allow their rapid identification and treatment as they can be life-threatening.

    Objective: Clinical presentation of soft-tissue infections and its management. Read More

    Management of Skin and Soft-Tissue Infections Before and After Clinical Pathway Implementation.
    Clin Pediatr (Phila) 2017 Oct 1:9922817738329. Epub 2017 Oct 1.
    2 Children's Hospital of Philadelphia, PA, USA.
    We evaluated if the introduction of a clinical pathway for skin and soft-tissue infections (SSTIs) would reduce methicillin-resistant Staphylococcus aureus (MRSA)-directed therapy for simple cellulitis and antibiotic use for simple abscess after drainage. We compared the treatment of SSTI during a 3-month prepathway and 11-month postpathway period. We included patients 57 days to 18 years old discharged from the emergency department (ED) with a diagnosis of cellulitis or abscess. Read More

    Acute myocardial infarction associated with thrombotic microangiopathy following a hump-nosed viper bite: a case report.
    J Med Case Rep 2017 Oct 30;11(1):305. Epub 2017 Oct 30.
    University Medical Unit, National Hospital of Sri Lanka, Colombo, Sri Lanka.
    Background: Hump-nosed viper bite is the commonest cause of venomous snakebite in Sri Lanka. Despite initially being considered a moderately venomous snake more recent reports have revealed that it could cause significant systemic envenoming leading to coagulopathy and acute kidney injury. However, myocardial infarction was not reported except for a single case, which occurred immediately after the snakebite. Read More

    Clinical Mimics: An Emergency Medicine-Focused Review of Cellulitis Mimics.
    J Emerg Med 2017 Oct;53(4):475-484
    Department of Emergency Medicine, The University of Texas Southwestern Medical Center, Dallas, Texas.
    Background: Cellulitis is a common clinical condition with low rates of morbidity and mortality if treated appropriately. Mimics of cellulitis presenting with erythema, edema, warmth, and pain can be associated with grave morbidity and mortality if misdiagnosed.

    Objective: This review investigates the signs and symptoms of cellulitis, mimics of cellulitis, and an approach to the management of both cellulitis and its mimics. Read More

    Salvage of Infected Breast Implants.
    Arch Plast Surg 2017 Oct 27. Epub 2017 Oct 27.
    Department of Plastic and Reconstructive Surgery, Institute for Human Tissue Restoration, Severance Hospital, Yonsei University College of Medicine, Seoul, Korea.
    Background: Implant-based breast reconstruction is being performed more frequently, and implants are associated with an increased risk of infection. We reviewed the clinical features of cases of implant infection and investigated the risk factors for breast device salvage failure.

    Methods: We retrospectively analyzed 771 patients who underwent implant-based breast reconstruction between January 2010 and December 2016. Read More

    Outbreak of invasive infections from subtype emm26.3 group A Streptococcus among homeless adults-Anchorage, Alaska, 2016-2017.
    Clin Infect Dis 2017 Oct 23. Epub 2017 Oct 23.
    Arctic Investigations Program, Division of Preparedness and Emerging Infections, National Center for Zoonotic and Emerging Infectious Diseases, Centers for Disease Control and Prevention, Anchorage, USA.
    Background: In 2016, we detected an outbreak of group A Streptococcus (GAS) invasive infections among the estimated 1000 persons experiencing homelessness (PEH) in Anchorage, Alaska. We characterized the outbreak and implemented a mass antibiotic intervention at homeless service facilities.

    Methods: We identified cases through the Alaska GAS laboratory-based surveillance system. Read More

    End-colostomy diverticulitis with parastomal phlegmon: A case report.
    Medicine (Baltimore) 2017 Oct;96(43):e8358
    aDepartment of General and Visceral Surgery, EHC Hospital, Morges b Department of Visceral Surgery, University Hospital CHUV, Lausanne cUnilabs, Department of Pathology, Lausanne, Switzerland.
    Rationale: Acute colonic diverticulitis is a well-known surgical emergency, which occurs in about 10 percent of patients known for diverticulosis.

    Patient Concerns: The case of a 77-year-old woman is reported, with past history of abdominoperineal resection with end-colostomy for low rectal adenocarcinoma, and who developed an acute colonic diverticulitis in a subcutaneous portion of colostomy with parastomal phlegmon.

    Diagnoses: Initial computed tomography imaging demonstrated a significant submucosal parietal edema with local fat tissues infiltration in regard of 3 diverticula. Read More

    Watch Out for Wild Animals: A Systematic Review of Upper Extremity Injuries Caused by Uncommon Species.
    Plast Reconstr Surg 2017 Nov;140(5):1008-1022
    Madison, Wis.; and Fort Collins, Colo. From the Division of Plastic Surgery, University of Wisconsin, Madison; and Northern Colorado Plastic and Hand Surgery.
    Background: Across the world, many species of nondomesticated animals dwell among humans in metropolitan areas. Rare animal bites pose a dilemma for hand surgeons, as they often result in operative injuries and recalcitrant infections. The authors treated an 85-year-old man who experienced severe cellulitis of the index finger following an opossum bite. Read More

    Cryptococcal cellulitis: A rare entity histologically mimicking a neutrophilic dermatosis.
    J Cutan Pathol 2017 Oct 25. Epub 2017 Oct 25.
    St. Joseph Mercy Health System, 5333 McAuley Dr. Suite 5003, Ypsilanti, MI, 48197.
    Cutaneous Cryptococcus infection presents classically with granulomatous and gelatinous reactive patterns. Cases mimicking neutrophilic dermatoses have not been described. Conversely, neutrophilic dermatoses with degrading cells mimicking cryptococcal organisms have been reported. Read More

    ASCOT: Autologous Bone Marrow Stem Cell Use for Osteoarthritis of the Thumb-First Carpometacarpal Joint.
    Plast Reconstr Surg Glob Open 2017 Sep 19;5(9):e1486. Epub 2017 Sep 19.
    Department of Plastic Surgery, Saint Vincent's University Hospital, Dublin, Ireland.
    Background: The first carpometacarpal joint (CMCJ) in the hand is a commonly affected joint by osteoarthritis. It causes significant thumb base pain, limiting functional capacity. Microfracturing and application of autologous stem cells has been performed on large joints such as the knee but has never been evaluated for use in the smaller joints in the hand. Read More

    Ludwig's Angina.
    Cureus 2017 Aug 21;9(8):e1588. Epub 2017 Aug 21.
    Internal Medicine, Kettering Medical Center.
    Ludwig's angina is a diffuse cellulitis in the submandibular, sublingual, and submental spaces, characterized by its propensity to spread rapidly to the surrounding tissues. Early recognition and treatment for Ludwig's angina are of paramount importance due to the myriad of complications that can occur in association with Ludwig's angina. Known complications of Ludwig's angina include carotid arterial rupture or sheath abscess, thrombophlebitis of the internal jugular vein, mediastinitis, empyema, pericardial effusion, osteomyelitis of the mandible, subphrenic abscess, aspiration pneumonia, and pleural effusion. Read More

    Ocular tuberculosis in Hospital Universiti Sains Malaysia - A case series.
    Ann Med Surg (Lond) 2017 Dec 13;24:25-30. Epub 2017 Oct 13.
    Department of Ophthalmology, School of Medical Sciences, Health Campus, Universiti Sains Malaysia, 16150 Kubang Kerian, Kelantan, Malaysia.
    Introduction: Ocular tuberculosis (TB) encompasses a broad spectrum of clinical manifestations affecting different structures of the eye. It is caused by Mycobacterium tuberculosis, a great ancient organism that induces various types of diseases and unfavorable outcomes if unrecognized and not well treated.

    Purpose: To report the clinical profile of 34 ocular TB cases observed during 6 years period in Hospital Universiti Sains Malaysia (HUSM). Read More

    A review of periorbital cellulitis guidelines in Fifty-One Acute Admitting Units in the United Kingdom.
    Clin Otolaryngol 2017 Oct 20. Epub 2017 Oct 20.
    Newcastle University.
    Periorbital cellulitis is an acute infection of the periorbital soft tissues with potential sight and life threatening complications that most commonly occurs in children([1]) . Post-septal abscess formation can cause loss of sight; furthermore, posterior spread of infection may progress to cavernous sinus thrombosis and intracranial infection([1, 2]) . In England April 2014-March 2015, 3687 patients attended hospital with periorbital cellulitis costing the National Health Service over £9. Read More

    Hyaluronidase allergy mimicking orbital cellulitis.
    Orbit 2017 Oct 20:1-5. Epub 2017 Oct 20.
    a Orbit, Oculoplasty, Reconstructive & Aesthetic Services , Sankara Nethralaya, Medical Research Foundation , Chennai , India.
    Purpose: Hyaluronidase enzyme is a common additive with local anesthetic agent to facilitate faster permeation of the anesthetic in periocular tissues during ophthalmic surgery. We report a series of five subjects presenting with clinical features mimicking orbital cellulitis following peribulbar anesthesia and consequently diagnosed with hyaluronidase hypersensitivity.

    Setting: The study was conducted at a tertiary eye care center in Southern India. Read More

    A rare case of orbital granulomatous inflammation from explosive hydraulic oil masquerading as orbital cellulitis.
    Orbit 2017 Oct 20:1-3. Epub 2017 Oct 20.
    a Department of Ophthalmology , University of Alberta , Edmonton , Canada.
    The differential diagnosis for acute orbital inflammation is broad. We report a case of granulomatous orbital inflammation due to high-pressure oil injury to the orbit presenting as an atypical orbital cellulitis. Here we review the presentation and treatment of orbital inflammation from oil. Read More

    Spontaneous Rupture of Lacrimal Gland Pleomorphic Adenoma: Pivotal Role in Masquerading Orbital Cellulitis.
    Ophthal Plast Reconstr Surg 2017 Oct 14. Epub 2017 Oct 14.
    *Ophthalmic Plastic & Reconstructive Surgery Department, Farabi Hospital, Tehran University of Medical Sciences, †Eye Research Center, Farabi Hospital, and ‡Pathology Department, Farabi Hospital, Tehran University of Medical Sciences, Tehran, Iran.
    The authors aim to report a 68-year-old patient presenting with acute swelling and redness of orbital area diagnosed initially as orbital cellulitis. Surgical excision was decided based on clinical and imaging findings with the diagnosis of pleomorphic adenoma of the lacrimal gland. Lacrimal gland pleomorphic adenoma usually presents with painless gradual swelling of upper eyelid. Read More

    Clinical, laboratory, and hemostatic findings in cats with naturally occurring sepsis.
    J Am Vet Med Assoc 2017 Nov;251(9):1025-1034
    OBJECTIVE To characterize clinical and laboratory findings in cats with naturally occurring sepsis, emphasizing hemostasis-related findings, and evaluate these variables for associations with patient outcomes. DESIGN Prospective, observational, clinical study. ANIMALS 31 cats with sepsis and 33 healthy control cats. Read More

    Procalcitonin as a diagnostic and prognostic marker in diabetic foot infection. A current literature review.
    Rom J Intern Med 2017 Oct 11. Epub 2017 Oct 11.
    Diabetic foot ulcers (DFUs) are a very common cause of mortality and morbidity. The distinction between infected and non-infected DFU remains a very challenging task for clinicians in everyday practice. Even when infection is documented, the spectrum of diabetic foot infection is wide, ranging from cellulitis and soft tissue infection to osteomyelitis. Read More

    Aggressive Combined Medical and Surgical Management of Mucormycosis Results in Disease Eradication in 2 Pediatric Patients.
    Plast Surg (Oakv) 2017 Aug 28;25(3):211-217. Epub 2017 Jun 28.
    Department of Plastic Surgery, McMaster University, Hamilton, Ontario, Canada.
    Rhinocerebral mucormycosis is an acute, rapidly fatal, fungal infection, classically involving the nasal mucosa and paranasal sinuses. It is an aggressive, opportunistic infection that frequently progresses to involve the orbit and cerebrum. Cerebral extension in immunocompromised patients is almost universally fatal. Read More

    Ultrasound evaluation of normal orbital preseptal thickness.
    Nepal J Ophthalmol 2017 Jan;9(18):56-59
    Introduction: Orbital preseptal thickness is an important parameter not only in diagnosis of orbital cellulitis but also in recent classification and management of dark eye circle (DEC).

    Objective: The aim of this study was to evaluate normal preseptal thickness and collect baseline data in normal skin in a given population with no orbital pathology.

    Materials & Method: Ultrasound was performed on 42 patients (23 females and 19 males) with clinically normal eyes and orbits for evaluation of normal orbital preseptal thickness. Read More

    Staphylococcus lugdunensis Infections of the Skin and Soft Tissue: A Case Series and Review.
    Dermatol Ther (Heidelb) 2017 Oct 11. Epub 2017 Oct 11.
    Department of Dermatology, University of California San Diego, La Jolla, CA, USA.
    Introduction: Staphylococcus lugdunensis (S. lugdunensis) is a coagulase-negative, Gram-positive bacterium that can be isolated as a component of normal skin flora in humans. However, more recently, it has also been documented as a culprit in skin and soft tissue infections. Read More

    Disseminated cryptococcosis in a patient taking tocilizumab for Castleman's disease.
    J Infect Chemother 2017 Oct 8. Epub 2017 Oct 8.
    Department of General Internal Medicine, Kobe City Medical Center General Hospital, Hyogo, Japan.
    Infections occur more frequently in patients receiving biologics. However, cryptococcal infection is uncommon in patients receiving tocilizumab, an interleukin-6 inhibitor, in contrast to patients receiving tumor necrosis factor-α inhibitors. In this report, we describe a case of disseminated cryptococcosis in a 55-year-old man who was receiving tocilizumab every 2 weeks along with daily prednisolone and cyclosporine for Castleman's disease. Read More

    Prophylactic Negative Pressure Wound Therapy for Obese Women After Cesarean Delivery: A Systematic Review and Meta-analysis.
    Obstet Gynecol 2017 Nov;130(5):969-978
    Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Utah, Salt Lake City, Utah; the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, and the Health Sciences Library, University of North Carolina-Chapel Hill, Chapel Hill, North Carolina; the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Duke University, Durham, North Carolina; and the Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Iowa, Iowa City, Iowa.
    Objective: To summarize available studies on wound complication outcomes after prophylactic negative pressure wound therapy for obese women (body mass index 30 or greater).

    Data Sources: We conducted a systematic review and meta-analysis using electronic database search (PubMed, Cumulative Index to Nursing and Allied Health Literature, EMBASE, Google scholar, and Web of Science), Cochrane, and trial registries including Read More

    Rare postoperative complication: Clostridium perfringens septic shock following elective abdominal surgery.
    BMJ Case Rep 2017 Oct 9;2017. Epub 2017 Oct 9.
    Department of General Surgery, Bedford Hospital NHS Trust, Bedford, UK.
    Postoperative infections are one of the most common complications in general surgery, and while rates have reduced with the routine administration of perioperative antibiotics, around 5% of patients undergoing a surgical procedure will develop an infective complication.(1) The Gram-positive, obligate anaerobe, Clostridium perfringens, is a well-known pathogen that forms part of both the environmental and gastrointestinal flora.(2) While more commonly associated with food poisoning, anaerobic cellulitis and traumatic gas gangrene, rare cases of spontaneous non-traumatic gas gangrene of abdominal viscera have also been recorded. Read More

    Sirolimus precipitating diabetes mellitus in a patient with congenital hyperinsulinaemic hypoglycaemia due to autosomal dominant ABCC8 mutation.
    J Pediatr Endocrinol Metab 2017 Oct;30(11):1219-1222
    Background: Sirolimus (mTOR inhibitor) is proven to be effective in children with congenital hyperinsulinism (CHI). Studies in animals suggest that sirolimus may have diabetogenic actions. However, its role in precipitating diabetes mellitus (DM) in children with CHI has not been reported. Read More

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