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Ophthalmology 2022 Jun 22. Epub 2022 Jun 22.

Department of Radiology and Nuclear Medicine, Amsterdam UMC, Vrije Universiteit Amsterdam, Cancer Center Amsterdam, Amsterdam, the Netherlands; European Retinoblastoma Imaging Collaboration (ERIC).

Objective: To investigate prevalence and MRI phenotype of retinoblastoma-associated orbital cellulitis. Additionally, this study aimed to identify postlaminar optic nerve enhancement patterns differentiating between inflammation and tumor invasion.

Design: A monocenter cohort study assessed the prevalence of orbital cellulitis features on MRI in retinoblastoma patients. Read More

Orbit 2022 Jun 24:1-3. Epub 2022 Jun 24.

Consultants in Ophthalmic and Facial Plastic Surgery, P.C, Southfield, MI, USA.

A 59-year-old woman with prior bilateral lower eyelid autologous fat transfer, subdermal micro-needling and fractional radiofrequency skin resurfacing presented with delayed left-sided preseptal cellulitis with small multinodular abscesses unresponsive to oral outpatient antibiotic regimens and inpatient intravenous antibiotics. Wound culture revealed infection treated successfully with a 4-month regimen of clarithromycin and tedizolid without recurrence. This case highlights (1) the need for vigilance and a broad differential in delayed post-operative wound infections including non-tuberculous mycobacterial infections, (2) resolution of infection without recurrence on clarithromycin and novel tedizolid oral antibiotic therapy, and (3) that caution should be exercised when performing combination autologous fat transfers with subdermal micro-needling procedures as the breakdown in skin integrity may potentiate infection. Read More

Curr Drug Deliv 2022 Jun 23. Epub 2022 Jun 23.

ISF College of Pharmacy, Moga, Punjab, 142001, India.

A frequent inflammatory pilosebaceous disorder that affects 80-90% of teenagers, acne vulgaris is still a concern for dermatologists and other doctors in the field of medicine. Acne has a significant psychosocial impact and is responsible for a bigger worldwide burden of disease than psoriasis, cellulitis, and melanoma, as measured by age-standardized disability-adjusted life years. Patients may experience psychological problems as well as severe skin scars as a result of the condition. Read More

Ned Tijdschr Geneeskd 2022 May 4;166. Epub 2022 May 4.

Albert Schweitzer Ziekenhuis, afd. Kindergeneeskunde, Dordrecht.

Background: An umbilical infection (omphalitis) is frequent in de neonatal period. The infection usually presents as a relatively mild cellulitis. However, in rare cases omphalitis has a complicated course. Read More

Cureus 2022 May 17;14(5):e25070. Epub 2022 May 17.

Dermatology, Raymond G. Murphy Department of Veterans Affairs Medical Center, Albuquerque, USA.

Although nontuberculous mycobacteria (NTM) infection is often thought of as a pulmonary disease, it can manifest on the skin in rare cases. In this report, we describe two cases of cutaneous  that presented as nonhealing rashes that were initially thought to be caused by bacterial cellulitis but did not respond to broad-spectrum antibiotics. In both cases, the rash began on the upper extremities. Read More

Clin Pediatr (Phila) 2022 Jun 21:99228221104385. Epub 2022 Jun 21.

Department of Pediatric Intensive Care Unit, The First Hospital of Jilin University, Changchun, Jilin, China.

Clinics (Sao Paulo) 2022 Jun 18;77:100063. Epub 2022 Jun 18.

Instituto do Câncer do Estado de São Paulo (ICESP), Hospital das Clínicas, Faculdade de Medicina, Universidade de São Paulo (HCFMUSP), São Paulo, SP, Brazil.

Background: The use of Indwelling Pleural Catheter (IPC) in the care of patients with Malignant Pleural Effusion (MPE) is well established, however studies involving public health systems of low and middle-income countries are still lacking. This study aimed to determine the effect of IPC on the respiratory symptoms and Quality of Life (QoL) of patients with MPE in the setting of a Brazilian public health system.

Methods: From August 2015 to November 2019, patients with MPE underwent IPC placement and were prospectively followed. Read More

Eur J Intern Med 2022 Jun 14. Epub 2022 Jun 14.

Division of Internal Medicine, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland; Department of Clinical Research, University of Basel, Schanzenstrasse 55, 4056 Basel, Switzerland. Electronic address:

Background: Guidance for blood culture (BC) collection is limited. Inappropriate BC collection may be associated with potentially harmful consequences for the patient such as unnecessary laboratory testing, treatment and additional costs. The aim of the study was to assess the appropriateness of BC collection and related knowledge and attitude of precribers. Read More

BMJ Case Rep 2022 Jun 20;15(6). Epub 2022 Jun 20.

Dentistry, All India Institute of Medical Sciences, Raipur, Chhattisgarh, India.

Ludwig's angina is a rapidly spreading, potentially fatal infection of deep fascial spaces of the neck leading to airway oedema and death. This, in recent times when associated with COVID-19 infection, possess treatment challenges making the patient susceptible to opportunistic infections with reduced healing potential. Owing to the multifactorial aetiology in our case and addressing them at the earliest, it is important to achieve favourable outcomes. Read More

JPRAS Open 2022 Sep 24;33:37-41. Epub 2022 May 24.

University of Colorado School of Medicine, Department of Otolaryngology, 12631 E 17th Ave, Aurora, CO 80045, United States.

Hyaluronic acid-based filler is the most popular injectable augmentation preparation due to its efficacy and safety compared to other injection fillers. The complication of infected filler is known, but it is unknown exactly how long filler persists prior to reabsorption. A case was presented of filler-exacerbated facial cellulitis that occurred 2. Read More

Hum Vaccin Immunother 2022 Jun 17:2073750. Epub 2022 Jun 17.

Optum, Epidemiology, Boston, MA, USA.

The 4-valent human papillomavirus (HPV) vaccine (4vHPV vaccine), Gardasil®, is indicated for the prevention of several HPV-related diseases. The objective was to assess the safety of 4vHPV vaccine administered to males as part of routine care. The study used a US health insurance claims database, and included males, age 9 to 26 years, who initiated 4vHPV between October 2009 and December 2016. Read More

Pediatr Dermatol 2022 Jun 17. Epub 2022 Jun 17.

Department of Dermatology, Massachusetts General Hospital, Boston, Massachusetts, USA.

The clinical features of 588 pediatric inpatients admitted with a diagnosis of cellulitis were reviewed with attention to diagnostic accuracy of true cellulitis (95.1%) versus pseudocellulitis (4.9%) and utilization of specialist consultations (28. Read More

Int J Gen Med 2022 9;15:5567-5578. Epub 2022 Jun 9.

Division of Infectious Disease, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, Taiwan.

Bilateral lower limbs cellulitis is a rare clinical condition, which has been overlooked for a long time. In daily clinical practice, bilateral cellulitis is a sporadically encountered condition; however, it remains a clinical challenge. There is a broad differential diagnosis for this clinical entity, and there is a lack of accepted international diagnostic criteria. Read More

Case Rep Ophthalmol 2022 Jan-Apr;13(1):265-269. Epub 2022 Apr 13.

Department of Ophthalmology, University of Colorado, Aurora, Colorado, USA.

Hematic pseudocysts are fibrous, nonepithelial lined capsules containing blood byproducts that typically present remotely following orbital fracture hardware implantation. Trauma, implant migration, and tissue erosion are believed to cause hemorrhage to pool within the capsular space. Risk factors include inadequate posterior fracture reduction and use of nonporous material which prevents fibrovascular ingrowth and stabilization. Read More

J Pediatr Hematol Oncol 2022 Jun 7. Epub 2022 Jun 7.

Department of Endocrinology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, Uttar Pradesh.

Corticosteroids and l-asparaginase used in the treatment of pediatric acute lymphoblastic leukemia (ALL) can cause drug-induced diabetes mellitus (DIDM). DIDM can lead to dyselectrolytemia, a higher risk of infections including cellulitis, bacteremia, fungemia, and a higher incidence of febrile neutropenia and may have an impact on the outcome of ALL. Literature on the management of DIDM among children with ALL is sparse and the diagnostic criteria for pediatric diabetes should be carefully applied considering the acute and transient nature of DIDM during ALL therapy. Read More

Ophthalmic Plast Reconstr Surg 2022 Jun 14. Epub 2022 Jun 14.

Department of Ophthalmology, Ophthalmic Plastic Surgery, Massachusetts Eye and Ear, Harvard Medical School, Boston, Massachusetts.

A 62-year-old man presented with diffuse, painless, left-sided preseptal edema, erythema, and woody induration extending to the left temple. The induration generated an orbital compartment syndrome with markedly elevated intraocular pressure necessitating lateral canthotomy and cantholysis. Although atypical for an infectious etiology, empiric broad-spectrum intravenous antibiotics were initiated with no improvement. Read More

Orbit 2022 Jun 13:1-6. Epub 2022 Jun 13.

Discipline of Ophthalmology & Visual Sciences, University of Adelaide, Adelaide, South Australia, Australia.

Purpose: Bacterial orbital cellulitis (OC) and diffuse non-specific orbital inflammation (DNSOI) may be challenging to differentiate clinically. This study investigates the utility of systemic inflammatory markers, namely white cell count (WCC) and C-reactive protein (CRP), in differentiating between OC and DNSOI.

Methods: A single-centre retrospective study of patients diagnosed with OC or DNSOI, between 2003 to 2021, who had WCC and/or CRP obtained at presentation. Read More

J Eur Acad Dermatol Venereol 2022 Jun 13. Epub 2022 Jun 13.

Dermatology Unit and Skin Bank, Department of Medical, Surgical and Neurosciences, Siena University Hospital, Siena, Italy.

Background: The spectrum of pustular skin disorders (PSD) is large and particularly challenging, including inflammatory, infectious and amicrobial diseases. Moreover, although pustules represent the unifying clinical feature, they can be absent or not fully developed in the early stage of the disease. The line-field confocal optical coherence tomography (LC-OCT) is a recently developed imaging technique able to perform a non-invasive, in vivo, examination of the epidermis and upper dermis, reaching very high image resolution and virtual histology. Read More

Infez Med 2022 1;30(2):285-292. Epub 2022 Jun 1.

Clinical Department of Medical, Surgical and Health Sciences, University of Trieste, Trieste, Italy.

is a genus of aerobic actinomycetes that are usually responsible for opportunistic infection in immunocompromised patients. Less frequently nocardiosis can interest immunocompetent population, causing especially primary cutaneous infections. Cutaneous involvement by spp. Read More

J Eur Acad Dermatol Venereol 2022 Jun 12. Epub 2022 Jun 12.

Department of Dermatology, Massachusetts General Hospital, Boston, MA, USA.

Ann Plast Surg 2022 06;88(5 Suppl 5):S473-S477

Division of Plastic Surgery, University of Alabama in Birmingham, Birmingham, AL.

Background: Autologous fat grafting is a popular technique for volume replacement in the breast and face. The efficacy, safety, and complication rate of this technique at the division of plastic surgery at the University of Alabama at Birmingham will be described in this review.

Methods: An institutional review board-approved retrospective review of patients undergoing fat grafting procedures from January 2015 to July 2018 was performed. Read More

J Clin Med 2022 May 30;11(11). Epub 2022 May 30.

College of Medicine, Chang Gung University, Taoyuan 33302, Taiwan.

Despite an increased incidence of secondary lower limb lymphedema (LLL) and severity of comorbidities with age, the impact of age on the effectiveness of lymphaticovenous anastomosis (LVA) in the older patients remains unclear.

Methods: This retrospective cohort study enrolled older patients (age > 65 years) with secondary unilateral LLL. All patients underwent supermicrosurgical LVA. Read More

J Am Acad Dermatol 2022 Jun 6. Epub 2022 Jun 6.

Department of Dermatology, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA; Rocky Mountain Regional Veterans Affairs Medical Center, Eastern Colorado Health Care System, Aurora, Colorado, USA.

FP Essent 2022 Jun;517:11-16

Department of Dermatology - University of North Carolina School of Medicine, 410 Market St Suite 400, Chapel Hill, NC 27516.

Alopecia affects men and women and can result in significant distress for patients. Alopecias can be categorized as nonscarring or scarring. Nonscarring alopecias include male and female pattern alopecias, alopecia areata, telogen effluvium, traction alopecia, trichotillomania, and tinea capitis. Read More

Front Pharmacol 2022 23;13:853012. Epub 2022 May 23.

Department of Emergency and Critical Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.

Jidabokuippo (JDI) () has been used in Japan to alleviate contusion-induced swelling and pain since medieval times. This review investigated the effects of JDI on various symptoms in patients with trauma or static blood. The PubMed and Igaku Chuo Zasshi databases were searched until 24 December 2021. Read More

Case Rep Infect Dis 2022 29;2022:2002488. Epub 2022 May 29.

Nursing, Florida International University, Miami, FL 33199, USA.

There has been a rise in antibiotic resistance in secondary conditions such as () due to overuse of antibiotics. Oral antibiotics are used to treat , which further disrupts the intestinal flora resulting in unwanted side effects. Naturopathic treatments often have fewer side effects and lower secondary infection risk than pharmaceutical interventions making them ideal for pediatric use. Read More

CJEM 2022 Jun 8. Epub 2022 Jun 8.

Clinical Epidemiology Program, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada.

Objectives: Emergency department (ED) patients with cellulitis requiring intravenous antibiotics may be treated via outpatient parenteral antibiotic therapy (OPAT) as opposed to hospitalization. The primary objective was to compare healthcare costs for the following strategies: community intravenous antibiotics with referral to an OPAT clinic operated by infectious disease specialists ('OPAT clinic' strategy); community intravenous antibiotics with return to ED if necessary ('return to ED' strategy); and hospital admission.

Methods: Using a hospital administrative database, we conducted a cost analysis using patient-level data of adult cellulitis patients presenting to two tertiary care EDs and were treated with intravenous antibiotics in one of three ways: OPAT clinic strategy; return to ED strategy; and hospital admission. Read More

Dermatol Ther 2022 Jun 8:e15626. Epub 2022 Jun 8.

Department of Dermatology, Consorci Sanitari Parc Taulí, Sabadell, Autonomous University of Barcelona, Sabadell, Spain.

Leuk Lymphoma 2022 Jun 7:1-8. Epub 2022 Jun 7.

Department of Hematology and Medical Oncology, Winship Cancer Institute, Emory University, Atlanta, GA, USA.

Infections originating in the skin/soft tissue are a major cause of mortality in cutaneous T-cell lymphoma (CTCL). We performed a retrospective analysis to characterize cutaneous cultures and assess risk factors for bacteremia among 69 patients with CTCL. Cutaneous infections and antimicrobial resistance were common. Read More

Aust Health Rev 2022 Jun 7. Epub 2022 Jun 7.

ObjectivesTo describe the burden of disease and hospitalisation costs in children with common infections using statewide administrative data.MethodsWe analysed hospitalisation prevalence and costs for 10 infections: appendicitis, cellulitis, cervical lymphadenitis, meningitis, osteomyelitis, pneumonia, pyelonephritis, sepsis, septic arthritis, and urinary tract infections in children aged <18 years admitted to hospital within New South Wales, Australia, using an activity-based management administrative dataset over three financial years (1 July 2016-30 June 2019).ResultsAmong 339 077 admissions, 28 748 (8. Read More