12,258 results match your criteria Cellulitis


The association of cellulitis incidence and meteorological factors in Taiwan.

Epidemiol Infect 2019 Jan;147:e138

Division of Urology, Department of Surgery,Chang Gung Memorial Hospital at Linkou,Taoyuan,Taiwan.

Cellulitis is a common infection of the skin and soft tissue. Susceptibility to cellulitis is related to microorganism virulence, the host immunity status and environmental factors. This retrospective study from 2001 to 2013 investigated relationships between the monthly incidence rate of cellulitis and meteorological factors using data from the Taiwanese Health Insurance Dataset and the Taiwanese Central Weather Bureau. Read More

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http://dx.doi.org/10.1017/S0950268819000323DOI Listing
January 2019
1 Read

Orbital Nasal-Type Extranodal Natural Killer/T-Cell Lymphoma: An Ongoing Diagnostic Challenge Further Confounded by Small-Cell Predominance.

Ophthalmic Plast Reconstr Surg 2019 Mar 8. Epub 2019 Mar 8.

Division of Ophthalmic Plastic and Reconstructive Surgery, Department of Ophthalmology, Massachusetts Eye and Ear Infirmary, Harvard Medical School, Boston, Massachusetts.

Purpose: To highlight the histopathologic diagnostic challenges of small-cell predominant extranodal nasal-type natural killer/T-cell lymphoma (ENTNKT) of the orbit.

Methods: Retrospective chart review and histopathologic study with immunohistochemistry and in situ hybridization of 3 cases.

Results: Three cases of ENTNKT presented to the Mass Eye and Ear emergency room as orbital cellulitis over 1 year. Read More

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http://dx.doi.org/10.1097/IOP.0000000000001333DOI Listing
March 2019
1 Read

Reactivation of latent and disseminated cytomegalovirus in a returning traveller with ulcerative colitis.

JMM Case Rep 2018 Dec 23;5(12):e005170. Epub 2018 Nov 23.

The Royal London Hospital, Whitechapel Road, Whitechapel, London E1 1BB, UK.

Introduction: We describe a case of progressive disseminated histoplasmosis (PDH) and disseminated cytomegalovirus (CMV) with development of haemophagocytic lymphohistiocytosis in a 62-year-old man of Bangladeshi origin living in the UK.

Case Presentation: The patient had a background of ulcerative colitis for which he took prednisolone and azathioprine. He presented with fever, lethargy, cough, weight loss and skin redness, and was initially treated for bacterial cellulitis and investigated for underlying malignancy. Read More

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http://dx.doi.org/10.1099/jmmcr.0.005170DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6412033PMC
December 2018

Radiographic Musculoskeletal Findings Indicating Opioid Misuse: An Overview for Orthopedic Surgeons.

HSS J 2019 Feb 8;15(1):84-92. Epub 2019 Jan 8.

2UHealth Sports Medicine Institute, University of Miami Miller School of Medicine, Coral Gables, FL USA.

Background: Given the high prevalence of musculoskeletal conditions in the USA, it is important for orthopedic surgeons to promptly identify patients who may be at risk for opioid misuse.

Questions/purposes: The aim of this literature review was to elucidate various musculoskeletal pathologies and complications, as seen on imaging, that may indicate opioid misuse or opioid use disorder.

Methods: A literature search was conducted using the PubMed, Scopus, and Cochrane Library databases for articles related to imaging findings associated with chronic opioid use or misuse in orthopedic patients. Read More

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http://dx.doi.org/10.1007/s11420-018-09654-yDOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384203PMC
February 2019

Herpetic whitlow of the toe presenting with severe viral cellulitis.

Pediatr Dermatol 2019 Mar 11. Epub 2019 Mar 11.

Division of Pediatric Infectious Diseases, Department of Pediatrics, Cedars-Sinai Medical Center, Los Angeles, California.

Herpetic whitlow of the toe is a common infection in an uncommon location, leading it to be frequently misdiagnosed; however, as the virus responds well to conservative management or antivirals alone, proper identification is necessary to prevent unnecessary interventions. We present a case of herpetic whitlow of the toe with an unusually ominous appearance in a previously healthy and otherwise well-appearing child. This case illustrates the spectrum of herpetic whitlow's clinical presentations and enourages consideration of the disease even for atypical location and severity. Read More

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http://doi.wiley.com/10.1111/pde.13795
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http://dx.doi.org/10.1111/pde.13795DOI Listing
March 2019
1 Read

Painful Scalp Nodules on an Active-Duty Sailor.

J Spec Oper Med 2019 ;19(1):128-129

Lesions of the scalp can present a challenging differential diagnosis to the primary care provider, especially in remote military settings where specialist care is not immediately available. Scalp lesions can be painful and disfiguring, and cause duty limitations if they interfere with the donning of personal protective equipment such as helmets, hardhats, or firefighting gear. We present a case of dissecting scalp cellulitis on an active- duty Navy Sailor who was leaving on an extended underway period on his ship the next day. Read More

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http://dx.doi.org/DOI Listing
January 2019

Efficacy of a collagen-fibrin sealant patch (TachoSil®) as adjuvant treatment in the inguinofemoral lymphadenectomy for vulvar cancer: a double-blind randomized-controlled trial.

Arch Gynecol Obstet 2019 Mar 11. Epub 2019 Mar 11.

Department of Obstetrics and Gynecology, AOUI Verona, University of Verona, Piazzale A. Stefani 1, 37126, Verona, Italy.

Purpose: To evaluate the effect of a collagen-fibrin sealant patch (TachoSil®) in preventing postoperative complications after inguinofemoral lymphadenectomy for vulvar cancer.

Methods: Double-blind randomized-controlled trial on consecutive patients undergoing bilateral inguinofemoral lymphadenectomy for vulvar cancer. Intraoperatively, inguinofemoral areas were randomized: one was treated with TachoSil®, while the contralateral had standard closure without collagen-fibrin sealant patch. Read More

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http://dx.doi.org/10.1007/s00404-019-05113-zDOI Listing

Patients' understanding of cellulitis and their information needs: a mixed-methods study in primary and secondary care.

Br J Gen Pract 2019 Mar 11. Epub 2019 Mar 11.

Primary Care and Population Science, Faculty of Medicine, University of Southampton, Southampton.

Background: Cellulitis is a painful infection of the skin and underlying tissues, commonly affecting the lower leg. Approximately one-third of people experience recurrence. Patients' ability to recover from cellulitis or prevent recurrence is likely to be influenced by their understanding of the condition. Read More

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http://dx.doi.org/10.3399/bjgp19X701873DOI Listing

Recurrent periorbital cellulitis associated with rhinosinusitis in children: Characteristics, course of disease, and management paradigm.

Int J Pediatr Otorhinolaryngol 2019 Feb 25;121:26-28. Epub 2019 Feb 25.

Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center and Schneider Children's Hospital, Petah Tikva, Israel; Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel.

Background: Recurrent periorbital cellulitis (RPOC) associated with rhinosinusitis is rarely noted and scarcely discussed in the literature. The aim of our study was to analyze the characteristics and disease course of a group of pediatric patients with RPOC.

Methods: The medical records of all pediatric patients with a diagnosis of RPOC treated in a tertiary children's hospital were retrieved. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.037DOI Listing
February 2019
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Computed tomography-guided navigation assisted drainage for inaccessible deep neck abscess: A case report.

Medicine (Baltimore) 2019 Mar;98(10):e14674

Department of Otorhinolaryngology-Head and Neck Surgery, Yonsei University Wonju College of Medicine, Wonju, Korea.

Rationale: Deep neck infections (DNIs) in the head and neck area are difficult to treat due to the anatomical complexity of the cervical region. Since inflammation causes changes in anatomy, it is often difficult to find the exact location of the abscess, which leads to failed surgical drainage.

Patient Concern: A 76-year-old female patient was referred to our clinic with trismus and right-side facial swelling. Read More

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http://dx.doi.org/10.1097/MD.0000000000014674DOI Listing
March 2019
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Efficacy and safety of intravenous ceftriaxone at home versus intravenous flucloxacillin in hospital for children with cellulitis (CHOICE): a single-centre, open-label, randomised, controlled, non-inferiority trial.

Lancet Infect Dis 2019 Mar 7. Epub 2019 Mar 7.

Department of Paediatrics, University of Melbourne, Melbourne, VIC, Australia; Murdoch Children's Research Institute, Melbourne, VIC, Australia; Infectious Diseases Unit, Department of General Medicine, The Royal Children's Hospital, Melbourne, VIC, Australia; Hospital-In-The-Home Department, The Royal Children's Hospital, Melbourne, VIC, Australia. Electronic address:

Background: Outpatient parenteral antimicrobial therapy in children is common despite no evidence of its efficacy or safety from clinical trials. We aimed to compare the efficacy and safety of intravenous antibiotic therapy at home with that of standard treatment in hospital for children with moderate to severe cellulitis.

Methods: The Cellulitis at Home or Inpatient in Children from the Emergency Department (CHOICE) trial was a randomised, controlled, non-inferiority trial in children aged 6 months to 18 years who presented to the emergency department at The Royal Children's Hospital (Melbourne, VIC, Australia) with uncomplicated moderate to severe cellulitis. Read More

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http://dx.doi.org/10.1016/S1473-3099(18)30729-1DOI Listing

Testicular wedge biopsy for fertility preservation in children at significant risk for azoospermia after gonadotoxic therapy.

J Pediatr Surg 2019 Feb 21. Epub 2019 Feb 21.

Department of Surgery, Northwestern University Feinberg School of Medicine, Chicago, IL, USA; Division of Pediatric Surgery, Ann and Robert H. Lurie Children's Hospital of Chicago, Chicago, IL, USA.

Background/purpose: Testicular tissue cryopreservation (TTC) provides an experimental option for fertility preservation for male children at significant risk for azoospermia owing to high-risk gonadotoxic treatments.

Methods: A single institution, retrospective review of TTC cases from 2015 to 2017. Children at significant risk for azoospermia were eligible for study inclusion. Read More

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http://dx.doi.org/10.1016/j.jpedsurg.2019.01.055DOI Listing
February 2019
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Extranodal NK/T cell lymphoma, nasal type, with retrobulbar extraconal phlegmon and naso-oral fistula.

BMJ Case Rep 2019 Mar 9;12(3). Epub 2019 Mar 9.

Department of Otolaryngology, Head and Neck Surgery, Barwon Health, Geelong, Victoria, Australia.

Extranodal natural killer (NK-)/T cell lymphoma, nasal type (ENKL), is a rare disease that often mimics rheumatological and infectious conditions and can therefore be difficult to diagnose. The authors present a case of a 55-year-old Vietnamese woman who was misdiagnosed with severe atrophic rhinitis and chronic sinus osteitis. Over a period of 8 months from initial referral, she underwent multiple biopsies and was treated with various antimicrobial regimens until the histopathological diagnosis of ENKL was finally made. Read More

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http://dx.doi.org/10.1136/bcr-2018-227160DOI Listing

Emergency Department Visits and Disease Burden Attributable to Ambulatory Care Sensitive Conditions in Elderly Adults.

Sci Rep 2019 Mar 7;9(1):3811. Epub 2019 Mar 7.

Institute of Occupational Medicine and Industrial Hygiene, College of Public Health, National Taiwan University, Taipei, Taiwan.

Many countries worldwide are aging rapidly, and the complex care needs of older adults generate an unprecedented demand for health services. Common reasons for elderly emergency department (ED) visits frequently involve conditions triggered by preventable infections also known as ambulatory care sensitive conditions (ACSCs). This study aims to describe the trend and the associated disease burden attributable to ACSC-related ED visits made by elderly patients and to characterize their ED use by nursing home residence. Read More

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http://dx.doi.org/10.1038/s41598-019-40206-4DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6405841PMC
March 2019
1 Read

A systematic review showing the lack of diagnostic criteria and tools developed for lower limb cellulitis.

Br J Dermatol 2019 Mar 7. Epub 2019 Mar 7.

Centre of Evidence Based Dermatology, University of Nottingham, Nottingham, UK.

Background: Cellulitis can be a difficult diagnosis to make. 31% of patients admitted from the emergency department with suspected lower limb cellulitis are misdiagnoses, with incorrect treatment potentially resulting in avoidable hospital admission and antibiotic prescribing.

Objective: We sought to identify diagnostic criteria or tools that have been developed for lower limb cellulitis. Read More

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http://dx.doi.org/10.1111/bjd.17857DOI Listing
March 2019
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Lipodermatosclerosis: the common skin condition often treated as cellulitis.

J R Coll Physicians Edinb 2019 03;49(1):41-42

Good Hope Hospital (University Hospitals Birmingham NHS Foundation Trust), Sutton Coldfield, UK.

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http://dx.doi.org/10.4997/JRCPE.2019.110DOI Listing
March 2019
1 Read

Ophthalmological emergencies. An epidemiological study: Are resources been used properly?

Arch Soc Esp Oftalmol 2019 Mar 2. Epub 2019 Mar 2.

UGC Oftalmología, Hospital Universitario Virgen Macarena, Sevilla, España; Departamento de Cirugía, Universidad de Sevilla, Sevilla, España.

Objectives: To determine the prevalence of ophthalmological emergency visits to two tertiary hospital in all age groups during years 2014 and 2015.

Methods: All patients who attended Ophthalmological Emergency Department from 1 January 2014 to 31 December 2015 were included in the study. The demographic variables studied were gender, age, place of origin, time of arrival, day of the week, month and year of the visit, the diagnosis, destination on discharge, total time of the visit and priority. Read More

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http://dx.doi.org/10.1016/j.oftal.2019.01.007DOI Listing
March 2019
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[Invasive disease due to Streptococcus pyogenes: Changes in incidence and prognostic factors].

An Pediatr (Barc) 2019 Mar 2. Epub 2019 Mar 2.

Sección de Enfermedades Infecciosas, Servicio de Pediatría, Hospital General Universitario Gregorio Marañón, Madrid, España; Universidad Complutense de Madrid, Madrid, España.

Introduction: Invasive group A streptococcal disease (iGASD) is a serious infection in children. Several studies have shown an increased incidence in the past years.

Objective: To evaluate the characteristics and outcome of iGASD in children, and to determine changes in incidence or severity. Read More

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http://dx.doi.org/10.1016/j.anpedi.2018.12.017DOI Listing
March 2019
3 Reads

A 60-year-old woman with recurrent cellulitis.

CMAJ 2019 Mar;191(9):E257-E259

Faculty of Medicine (Vijh) and Department of Medicine (Shah, Andany), University of Toronto; Division of General Internal Medicine (Shah), Toronto Western Hospital; Division of Infectious Diseases (Andany), Sunnybrook Health Sciences Centre, Toronto, Ont.

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http://dx.doi.org/10.1503/cmaj.180686DOI Listing
March 2019
2 Reads

c-ANCA vasculitis after initiation of denosumab.

BMJ Case Rep 2019 Mar 1;12(3). Epub 2019 Mar 1.

University of Miami Miller School of Medicine at Holy Cross Hospital, Fort Lauderdale, Florida, USA.

Denosumab is a fully human antibody to receptor activator of nuclear factor kappa-B ligand (RANKL), and it is administered every 6 months in women with postmenopausal osteoporosis (PMO) at high risk for fracture. Adverse effects of denosumab include musculoskeletal pain, hypercholesterolaemia, symptomatic hypocalcaemia, osteonecrosis of the jaw and cutaneous events such as angioedema, cellulitis and pustular dermatitis. While the possibility of vasculitis was mentioned in the product Monograph as well as in the WHO Newsletter, this is the first case, to our knowledge, of cytoplasmic-ANCA (c-ANCA) associated vasculitis officially published in the literature. Read More

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http://dx.doi.org/10.1136/bcr-2018-228336DOI Listing

Evaluation of an emergency department to outpatient parenteral antibiotic therapy program for cellulitis.

Am J Emerg Med 2019 Feb 21. Epub 2019 Feb 21.

Department of Emergency Medicine, University of Ottawa, Ottawa, Canada; Clinical Epidemiology Program, The Ottawa Hospital Research Institute, University of Ottawa, Canada; School of Epidemiology and Public Health, University of Ottawa, Ottawa, Ottawa, Canada.

Objective: Emergency department (ED) patients with non-purulent skin and soft tissue infections (SSTIs) requiring intravenous antibiotics may be managed via outpatient parenteral antibiotic therapy (OPAT). Prospective studies describing the performance of an ED-to-OPAT clinic program are lacking. The primary objective was to determine the OPAT treatment failure rate for ED patients with non-purulent SSTIs. Read More

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http://dx.doi.org/10.1016/j.ajem.2019.02.023DOI Listing
February 2019

Do Groin Drains Reduce Postoperative Morbidity in Women Undergoing Inguinofemoral Lymphadenectomy for Vulvar Cancer?

Int J Gynecol Cancer 2018 01;28(1):183-187

King Edward Memorial Hospital, Subiaco.

Objective: Sentinel lymph node biopsy has been widely adopted in the surgical management of women with early-stage vulvar cancer, but many patients require inguinofemoral lymphadenectomy (IFL). Following IFL, many surgeons drain the groin to prevent lymphocyst formation despite a lack of evidence to support this practice. Our objective was to investigate whether groin drains after IFL are associated with reduced postoperative morbidity in women undergoing surgery for vulvar cancer. Read More

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http://dx.doi.org/10.1097/IGC.0000000000001146DOI Listing
January 2018
1 Read

Duration of antibiotic treatment for common infections in English primary care: cross sectional analysis and comparison with guidelines.

BMJ 2019 Feb 27;364:l440. Epub 2019 Feb 27.

Modelling and Economics Unit, National Infection Service, Public Health England, London NW9 5EQ, UK.

Objective: To evaluate the duration of prescriptions for antibiotic treatment for common infections in English primary care and to compare this with guideline recommendations.

Design: Cross sectional study.

Setting: General practices contributing to The Health Improvement Network database, 2013-15. Read More

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http://dx.doi.org/10.1136/bmj.l440DOI Listing
February 2019
2 Reads

Analysis of Readmissions Following Hospitalization for Cellulitis in the United States.

JAMA Dermatol 2019 Feb 27. Epub 2019 Feb 27.

Harvard Medical School, Boston, Massachusetts.

Importance: Cellulitis commonly results in hospitalization. Limited data on the proportion of cellulitis admissions associated with readmission are available.

Objective: To characterize the US national readmission rate associated with hospitalization for treatment of cellulitis. Read More

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http://dx.doi.org/10.1001/jamadermatol.2018.4650DOI Listing
February 2019
1 Read

Decompression of Ludwig's angina in a pregnant patient under bilateral superficial cervical plexus block.

J Perioper Pract 2019 Feb 27:1750458919834195. Epub 2019 Feb 27.

Department of OMFS, Aligarh Muslim University, Aligarh, India.

Ludwig's angina is defined as a potentially lethal, rapidly spreading cellulitis, involving the sublingual and submandibular spaces, and is manifested by a brawny suprahyoid induration, tender swelling in the floor of the mouth, and elevation and posterior displacement of the tongue. During a life-threatening infection such as Ludwig's angina, the mother and foetus are vulnerable to septicemia and asphyxia. We describe a case of decompression of Ludwig's angina in a 28 weeks pregnant patient under bilateral superficial cervical plexus block. Read More

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http://dx.doi.org/10.1177/1750458919834195DOI Listing
February 2019
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Gracilis musculotendinous free flap for lower extremity reconstruction after surgical removal of malignant tumors: A report of five cases.

Microsurgery 2019 Feb 27. Epub 2019 Feb 27.

Department of Orthopaedic Surgery, The Johns Hopkins School of Medicine, Baltimore, Maryland.

Background: Lower extremity reconstruction is challenging because of the need to restore form and function. Despite the many options for soft-tissue coverage, little research has addressed combined tendon and soft-tissue reconstitution. We present a series of patients undergoing lower extremity tendon reconstruction and wound coverage with a single free gracilis flap and its tendon. Read More

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http://dx.doi.org/10.1002/micr.30444DOI Listing
February 2019
6 Reads

Tracheoesophageal Puncture Site Closure With Butterfly Cartilage Graft.

J Craniofac Surg 2019 Feb 16. Epub 2019 Feb 16.

Bezmialem Vakif University, Faculty of Medicine, Department of Otorhinolaryngology, Fatih, Istanbul, Turkey.

A tracheoesophageal voice prosthesis is very effective for improving speech after total laryngectomy. Although it is generally a safe method, it may be necessary to close the tracheoesophageal fistula due to complications such as prosthesis-related cellulitis, granulation tissue formation, tracheoesophageal fistula necrosis, or salivary leakage around the prosthesis. Surgical and non-surgical methods for closure have been described. Read More

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http://dx.doi.org/10.1097/SCS.0000000000005286DOI Listing
February 2019
1 Read

A retrospective study (2001-2017) of acute and chronic morbidity and mortality associated with Staphylococcus aureus bacteraemia in a tertiary neonatal intensive care unit.

Ir J Med Sci 2019 Feb 25. Epub 2019 Feb 25.

Clinical Innovation Unit, Rotunda Hospital, Dublin 1, Ireland.

Background: Staphylococcus aureus bacteraemia (SAB) in NICU patients can cause significant morbidity and mortality.

Aims: To review early and late neonatal SAB with regard to risk factors, treatment, acute complications and long-term outcomes.

Methods: A retrospective study of laboratory confirmed SAB over a 16-year period (November 2001-January 2017) in a tertiary neonatal unit in Ireland. Read More

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http://link.springer.com/10.1007/s11845-019-01992-y
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http://dx.doi.org/10.1007/s11845-019-01992-yDOI Listing
February 2019
2 Reads

Necrotizing Fasciitis Following Herpes Zoster Ophthalmicus in an Immunocompromised Patient.

Case Rep Ophthalmol Med 2019 20;2019:4534153. Epub 2019 Jan 20.

Fondazione Policlinico Universitario A. Gemelli, Università Cattolica del S. Cuore, Rome, Italy.

Necrotizing fasciitis (NF) is a rare infection that spreads rapidly along the subcutaneous soft tissue planes. NF rarely involves the periorbital region due to the excellent blood supply of this region. We report a case of periorbital necrotising fasciitis following herpes zoster (HZ) in an immunocompromised 70-year-old patient with a dramatically rapid evolution into septic shock. Read More

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http://dx.doi.org/10.1155/2019/4534153DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6360555PMC
January 2019
3 Reads

Antibiotic Prescribing Patterns Among Dental Professionals In Massachusetts.

Pediatr Dent 2019 Jan;41(1):25-30

Dr. Sonis is a senior clinical associate, Department of Dentistry, Boston Children's Hospital, and a professor, Department of Developmental Biology, Harvard School of Dental Medicine, Boston, Mass., USA.

The purposes of this study were to investigate prescribing patterns of antibiotics for the management of common pediatric oral infections, and to and identify the independent predictors of antibiotic preference across different groups of dental practitioners in Massachusetts, USA. A cross-sectional survey assessed antibiotic prescribing practices of general dentists, pediatric dentists, endodontists, and oral surgeons based on a series of clinical scenarios where antibiotic coverage may be warranted. The appropriate therapeutic management of patients with facial cellulitis occurred across all clinical groups. Read More

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January 2019

Infections in Older Adults: A Case-Based Discussion Series Emphasizing Antibiotic Stewardship.

MedEdPORTAL 2018 Sep 21;14:10754. Epub 2018 Sep 21.

Physician-Scientist, Geriatric Research Education and Clinical Center, Louis Stokes Cleveland Veterans Affairs Medical Center.

Introduction: Compared with younger populations, adults 65 years and older are more likely to suffer infection-related morbidity and mortality, experience antibiotic-related adverse events, and acquire multidrug-resistant organisms. We developed a series of case-based discussions that stressed antibiotic stewardship while addressing management of common infections in older adults.

Methods: Five 1-hour case-based discussions address recognition, diagnosis, and management of infections common in older adults, including those living in long-term care settings: urinary tract infections, upper respiratory tract infections, lower respiratory tract infections, skin and soft tissue infections, and infection. Read More

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http://dx.doi.org/10.15766/mep_2374-8265.10754DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6346280PMC
September 2018
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Scedosporium apiospermum: A Rare Cause of Aggressive Orbital Apex Syndrome.

Cureus 2018 Dec 17;10(12):e3743. Epub 2018 Dec 17.

Ophthalmology, Hospital Tengku Ampuan Rahimah, Klang, MYS.

Orbital apex syndrome (OAS) is a localized orbital cellulitis at the orbital apex that can cause vision loss from optic neuropathy and ophthalmoplegia involving multiple cranial nerves. Herein, we report a rare and rapidly progressive case of OAS secondary to fungal pansinusitis caused by in an immunocompromised patient following the extraction of abscessed teeth. A 48-year-old man with diabetes mellitus who had failed to adhere to his treatment presented with complaints of a right-sided headache and toothache for two weeks, with nausea and vomiting for two days prior to presentation. Read More

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http://dx.doi.org/10.7759/cureus.3743DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6384044PMC
December 2018
2 Reads

Clostridioides difficile-related toxic megacolon after Cryptococcus neoformans cellulitis: A complex of two rare infections in an immunocompromised host.

J Infect Chemother 2019 Feb 21. Epub 2019 Feb 21.

Department of Clinical Infectious Diseases, Aichi Medical University Hospital, Nagakute, Aichi, Japan; Department of Infection Control and Prevention, Aichi Medical University Hospital, Nagakute, Aichi, Japan. Electronic address:

A 76-year-old Japanese woman was admitted due to uncontrolled cellulitis of the right lower leg. She had deep vein thrombosis on the right limb. Moreover, she had a long history of rheumatoid arthritis treated with corticosteroids. Read More

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http://dx.doi.org/10.1016/j.jiac.2018.12.003DOI Listing
February 2019
2 Reads

Radiographic Soft Tissue Thickness Differentiating Pyogenic Flexor Tenosynovitis From Other Finger Infections.

J Hand Surg Am 2019 Feb 20. Epub 2019 Feb 20.

Department of Orthopaedics and Sports Medicine, University of Washington, Harborview Medical Center, Seattle, WA. Electronic address:

Purpose: Characteristic swelling has been described as a differentiating sign of pyogenic flexor tenosynovitis (PFT) but has not been validated. We conducted a retrospective study of adults with finger infections to compare radiographic parameters of soft tissue dimensions. Our hypothesis was that in patients with digit infections, radiographic soft tissue thickness measurement would differ between PFT and non-PFT infected digits. Read More

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http://dx.doi.org/10.1016/j.jhsa.2019.01.013DOI Listing
February 2019
1 Read

Single-Dose Dalbavancin and Patient Satisfaction in an Outpatient Setting in the Treatment of Acute Bacterial Skin and Skin Structure Infections.

J Glob Antimicrob Resist 2019 Feb 20. Epub 2019 Feb 20.

Allergan plc, 5 Giralda Farms, Madison, NJ 07940, USA. Electronic address:

Objectives: Treatment of acute bacterial skin and skin structure infections (ABSSSI) in the outpatient setting has potential advantages. We performed a subanalysis of outcomes for patients treated as outpatients versus inpatients with dalbavancin, a long-acting lipoglycopeptide, in a phase 3 clinical trial of ABSSSI.

Methods: The study was a double-blind trial of patients with ABSSSI randomized to receive dalbavancin 1500 mg intravenously as a single dose or 2 doses (1000 mg followed by 500 mg a week later). Read More

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http://dx.doi.org/10.1016/j.jgar.2019.02.007DOI Listing
February 2019
1 Read

Preservation of retinoblastoma group E eyes with neovascular glaucoma using intravenous chemotherapy: risk factors and outcomes.

Br J Ophthalmol 2019 Feb 22. Epub 2019 Feb 22.

Ocular Oncology Service, Centre for Sight, Hyderabad, India.

Background/aim: To report the outcomes of retinoblastoma group E eyes with neovascular glaucoma (NVG) treated conservatively with intravenous chemotherapy and investigate factors associated with eye salvage and secondary enucleation.

Methods: This is a retrospective, comparative, interventional case series. The outcome measures were life salvage, eye salvage and vision salvage. Read More

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http://dx.doi.org/10.1136/bjophthalmol-2018-313442DOI Listing
February 2019
2 Reads

Reactive thrombocytosis in acute infectious diseases: Prevalence, characteristics and timing.

Eur J Intern Med 2019 Feb 19. Epub 2019 Feb 19.

Departments of Medicine (AS, ID) and Imaging (JK), Laniado Hospital, Sanz Medical Centre, Netanya, Israel.

Background: Reactive thrombocytosis is known to occur in infectious, inflammatory and neoplastic diseases. However, the characteristics of its association with acute infections (ID) has not been systematically studied.

Setting: A department of internal medicine in a general teaching hospital. Read More

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http://dx.doi.org/10.1016/j.ejim.2019.02.010DOI Listing
February 2019

North of Home: Obligations to Families of Undocumented Patients.

Hastings Cent Rep 2019 Jan;49(1):12-14

Undocumented and undomiciled, Gustavo Jiménez had been in the United States for several years. He knew his leg wasn't right when it began to swell and redden. After the cellulitis spread to his bloodstream, he was found unconscious on the street and admitted to the intensive care unit. Read More

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http://dx.doi.org/10.1002/hast.972DOI Listing
January 2019
1 Read

Orbital Complications of Rhinosinusitis in the Adult Population: Analysis of Cases Presenting to a Tertiary Medical Center Over a 13-Year Period.

Ann Otol Rhinol Laryngol 2019 Feb 21:3489419832624. Epub 2019 Feb 21.

1 Department of Otolaryngology Head and Neck Surgery, Rabin Medical Center, Petah-Tikva.

Background:: Orbital complications of rhinosinusitis in adults are scarcely discussed in the literature.

Objective:: To review our experience with the management of orbital complications of rhinosinusitis in the adult patient population and identify key factors in the characteristics and management of these patients.

Design:: Retrospective case series during the years 2004 to 2016 in a tertiary referral center including all patients with rhinosinusitis and orbital complications. Read More

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http://dx.doi.org/10.1177/0003489419832624DOI Listing
February 2019
2 Reads

Skin Complications of Orthopedic Procedures and Devices.

Iran J Public Health 2018 Dec;47(12):1937-1944

Kassir Dermatology, Dallas, Texas, USA.

Background: Knowledge of skin complications and contributing factors in orthopedic patients is important for design and development of preventive approaches. Therefore, this study was designed to assess skin complications in orthopedic patients.

Methods: In this case-series study, 126 orthopedic patients referred to Rasoul-e-Akram and Bahman hospitals from 2012 to 2016 with skin complications were analyzed. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379618PMC
December 2018
2 Reads

Diagnostic Stewardship: A Clinical Decision Rule for Blood Cultures in Community-Onset Methicillin-Resistant Staphylococcus aureus (MRSA) Skin and Soft Tissue Infections.

Infect Dis Ther 2019 Feb 19. Epub 2019 Feb 19.

Anti-Infective Research Laboratory, College of Pharmacy and Health Sciences, Wayne State University, Detroit, MI, USA.

Introduction: The emergence, spread and persistence of methicillin-resistant Staphylococcus aureus (MRSA) as a causative pathogen in community-onset (CO) skin and soft tissue infections (SSTIs) have resulted in substantial changes in the management of these infections. The indications for obtaining blood cultures in patients with CO-MRSA SSTIs remain poorly defined. The objectives of this study were to derive and validate a clinical decision rule that predicts the probability of MRSA bacteremia in CO-MRSA SSTIs and to identify a low-risk population for whom blood cultures may be safely omitted. Read More

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http://link.springer.com/10.1007/s40121-019-0238-1
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http://dx.doi.org/10.1007/s40121-019-0238-1DOI Listing
February 2019
10 Reads

Impact of Azithromycin-Based Extended-Spectrum Antibiotic Prophylaxis on Noninfectious Cesarean Wound Complications.

Am J Perinatol 2019 Feb 19. Epub 2019 Feb 19.

Division of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, University of Alabama at Birmingham, Birmingham, Alabama.

Objective:  Adding azithromycin to standard antibiotic prophylaxis for unscheduled cesarean delivery has been shown to reduce postcesarean infections. Because wound infection with ureaplasmas may not be overtly purulent, we assessed the hypothesis that azithromycin-based extended-spectrum antibiotic prophylaxis also reduces wound complications that are identified as noninfectious.

Study Design:  This is a secondary analysis of the C/SOAP (Cesarean Section Optimal Antibiotic Prophylaxis) randomized controlled trial, which enrolled women with singleton pregnancies ≥24 weeks who were undergoing nonelective cesarean. Read More

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http://dx.doi.org/10.1055/s-0039-1679914DOI Listing
February 2019
3 Reads

Common Community-acquired Bacterial Skin and Soft-tissue Infections in Children: an Intersociety Consensus on Impetigo, Abscess, and Cellulitis Treatment.

Clin Ther 2019 Feb 15. Epub 2019 Feb 15.

Division of Dermatology, Department of Experimental, Diagnostic and Specialty Medicine, Sant'Orsola-Malpighi Hospital, University of Bologna, Bologna, Italy.

Purpose: The main objective of this article was to offer practical suggestions, given the existing evidence, for identifying and managing bacterial impetigo, abscess, and cellulitis in ambulatory and hospital settings.

Methods: Five Italian pediatric societies appointed a core working group. In selected conditions, specially trained personnel evaluated quality assessment of treatment strategies according to the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology. Read More

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http://dx.doi.org/10.1016/j.clinthera.2019.01.010DOI Listing
February 2019
6 Reads
2.731 Impact Factor

Trauma-associated Pott's puffy tumor: an ophthalmologic perspective.

Orbit 2019 Feb 18:1-3. Epub 2019 Feb 18.

a Division of Ophthalmology , Ann & Robert H. Lurie Children's Hospital of Chicago , Chicago , IL , USA.

Pott's puffy tumor is a significant complication of frontal sinusitis that leads to frontal bone osteomyelitis and can be associated with frontal swelling, subperiosteal abscess, and intracranial abscess. It may be associated with antecedent trauma and typically presents in adolescents. Orbital involvement is rarely reported. Read More

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http://dx.doi.org/10.1080/01676830.2019.1573909DOI Listing
February 2019
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Pediatric preseptal and orbital cellulitis: A 10-year experience.

Int J Pediatr Otorhinolaryngol 2019 Feb 7;120:82-88. Epub 2019 Feb 7.

Pediatrics Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Portugal.

Objective: Characterize clinical features, epidemiology and treatment of hospitalized pediatric cases of preseptal and orbital cellulitis.

Methods: Retrospective study of children/adolescents admitted to a central hospital with preseptal and orbital cellulitis between 2007 and 2017.

Results: A total of 122 cases were included, 80. Read More

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http://dx.doi.org/10.1016/j.ijporl.2019.02.003DOI Listing
February 2019
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First case report of thyroid abscess caused by Helicobacter cinaedi presenting with thyroid storm.

BMC Infect Dis 2019 Feb 15;19(1):166. Epub 2019 Feb 15.

Division of Pulmonary Medicine, Department of Internal Medicine, Federation of National Public Service Personnel Mutual Aid Associations, Tachikawa Hospital, 4-2-22 Nishikicho, Tachikawa, Tokyo, 190-8531, Japan.

Background: Helicobacter cinaedi is a microaerobic Gram-negative spiral-shaped bacterium that causes enteritis, cellulitis, and bacteremia in both immunocompromised and immunocompetent patients. While there have been increasing numbers of reported H. cinaedi infections recently, there has been no thyroid abscess case caused by H. Read More

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http://dx.doi.org/10.1186/s12879-019-3808-7DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6377776PMC
February 2019
1 Read

Factors associated with readmission and mortality in adult patients with skin and soft tissue infections.

Int J Dermatol 2019 Feb 15. Epub 2019 Feb 15.

Clinical Microbiology Department, Son Llàtzer Hospital, Balearic Islands, Spain.

Background: Skin and soft tissue infections (SSTIs) are a common cause of consultation, and complicated cases require hospitalization. We describe factors that are related to readmission and/or mortality of hospitalized patients diagnosed with SSTIs.

Methods: Retrospective review of hospital-admitted patients with a diagnosis of cellulitis, abscess, hidradenitis, fasciitis, and Fournier's gangrene. Read More

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http://dx.doi.org/10.1111/ijd.14390DOI Listing
February 2019
2 Reads

Systematic review of the role of corticosteroids in cervicofacial infections.

Br J Oral Maxillofac Surg 2019 Feb 12. Epub 2019 Feb 12.

Maxillofacial surgery Trainees Research Collaborative, Queen Elizabeth University Hospital, Glasgow.

The role of corticosteroids in the management of cervicofacial infections continues to cause controversy. Systemic anti-inflammatory and immunomodulatory effects that reduce swelling and improve symptoms in the head and neck may make these agents an effective addition to the antibiotics used and to surgical management, although this same effect may dull the physiological response to infection, and allow infections to progress. We have systematically reviewed the evidence for the use of corticosteroids in common cervicofacial infections following the PRISMA guidelines. Read More

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http://dx.doi.org/10.1016/j.bjoms.2019.01.010DOI Listing
February 2019

Association between Drug Use and In-hospital Outcomes after Infrainguinal Bypass for Peripheral Arterial Occlusive Disease.

Ann Vasc Surg 2019 Feb 13. Epub 2019 Feb 13.

Department of Surgery, Johns Hopkins Bayview Vascular and Endovascular Research Center, Baltimore, MD; Department of Surgery, University of California San Diego, La Jolla, CA. Electronic address:

Background: Drug abuse may affect lower extremity vessels due to ischemia following intra-arterial injections, vasospasm, arterial and venous pseudoaneurysms, arteriovenous fistulae, vasculitis, and complicated abscesses. Little is known about the outcomes of lower extremity bypass (LEB) for peripheral arterial disease (PAD) in patients with a history of drug abuse disorder. The aim of this study is to evaluate the outcomes of LEB in this patient population. Read More

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http://dx.doi.org/10.1016/j.avsg.2018.12.070DOI Listing
February 2019
2 Reads

Reactions to Gudair® vaccination identified in sheep used for biomedical research.

Aust Vet J 2019 Mar 13;97(3):56-60. Epub 2019 Feb 13.

Ear Sciences Centre, School of Medicine, the University of Western Australia, Crawley, WA, Australia.

Case Report: We report Gudair® vaccination (against ovine Johne's disease, Mycobacterium avium subsp. paratuberculosis) site reactions in sheep used as a surgical model in biomedical research and discuss the actual and potential impact these lesions may have on surgical procedures, particularly in otology. Nine female Merino-cross sheep (Ovis aries) were enrolled in a project designed to investigate the healing capabilities of the malleus bone in the middle ear. Read More

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http://dx.doi.org/10.1111/avj.12788DOI Listing
March 2019
1 Read