1,500 results match your criteria Cavernous Sinus Thrombosis

Radiographic and Clinical Analysis of Cranio-Maxillofacial Complications of Cavernous Sinus Thrombosis Among 256 COVID-19 Patients.

J Craniofac Surg 2022 Jun 27. Epub 2022 Jun 27.

Tashkent Medical Academy.

Background: A heavy burden of cranio-maxillofacial complications may be encountered in corona virus disease-2019 patients due to the associated coagulopathy and inflammatory consequences of the disease. This study aims to describe clinical and radiographic features of these complications in 256 patients who developed 1 or more of the following complications: cavernous sinus thrombosis, osteomyelitis or necrosis of the jaws.

Methods: Clinical assessment of cranial nerve function and general clinical assessment were performed. Read More

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Transorbital embolization of cavernous sinus dural arterio-venous malformations with surgical exposure and catheterization of the superior ophthalmic vein.

Interv Neuroradiol 2022 Jun 26:15910199221110967. Epub 2022 Jun 26.

Department of Otorhinolaryngology, Head and Neck Surgery; Saarland University Medical Center, Homburg/Saar, Germany.

Purpose: Cavernous sinus dural arterio-venous malformations (dAVF) represent a pathologic connection between branches of the internal and/or external carotid artery and the cavernous sinus. Standard endovascular approaches for dAVF treatment are transvenous embolization through the inferior petrosal sinus or the facial vein and transarterial embolization. These approaches are not always successful or feasible, and alternative techniques are required. Read More

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Bilateral Dilation of the Superior Ophthalmic Veins-Consequential or Incidental.

Neurohospitalist 2022 Jul 22;12(3):583-584. Epub 2022 Apr 22.

Department of Neurology, University of South Carolina School of Medicine, Columbia, SC, USA.

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Series of isolated sphenoid disease: Often neglected but perilous.

SAGE Open Med Case Rep 2022 19;10:2050313X221097757. Epub 2022 May 19.

Department of Otorhinolaryngology, Hospital Sultanah Bahiyah, Alor Setar, Malaysia.

Isolated sphenoid sinus disease (ISSD) is an uncommon entity and may present with non-specific symptoms. As sphenoid sinus is located adjacent to vital structures, a diseased sphenoid sinus can potentially lead to devastating complications such as cranial neuropathies, cavernous sinus thrombosis and intracranial abscess. Herein, we report a case series of three patients who presented with different localization of headache as their main symptom. Read More

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An Integrated Approach on the Diagnosis of Cerebral Veins and Dural Sinuses Thrombosis (a Narrative Review).

Life (Basel) 2022 May 11;12(5). Epub 2022 May 11.

Department of Neurosciences-Division of Neurology, Victor Babes University of Medicine and Pharmacy, E. Murgu Sq., no.2, 300041 Timisoara, Romania.

(1) Objective: This review paper aims to discuss multiple aspects of cerebral venous thrombosis (CVT), including epidemiology, etiology, pathophysiology, and clinical presentation. Different neuroimaging methods for diagnosis of CVT, such as computer tomography CT/CT Venography (CTV), and Magnetic Resonance Imaging (MRI)/MR Venography (MRV) will be presented. (2) Methods: A literature analysis using PubMed and the MEDLINE sub-engine was done using the terms: cerebral venous thrombosis, thrombophilia, and imaging. Read More

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Misdirection of a nasopharyngeal SARS-CoV-2 swab: An unexpected complication.

Otolaryngol Case Rep 2022 Sep 6;24:100439. Epub 2022 May 6.

Otolaryngology Department, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.

Background: The diagnosis of coronavirus disease (COVID-19) is based on detecting viral RNA of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in the nasal cavities and the nasopharynx. Millions of nasopharyngeal swab tests are currently performed daily worldwide; complications of the procedure are uncommon, but occasionally they occur.

Case Report: We describe the case of a 79-year-old man who developed right orbital cellulitis after a nasopharyngeal swab test for SARS-CoV-2. Read More

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September 2022

Misdiagnosis of fungal infections of the orbit.

Can J Ophthalmol 2022 May 4. Epub 2022 May 4.

From the Department of Ophthalmology and Visual Sciences, Carver College of Medicine, University of Iowa Hospitals and Clinics, Iowa City, Iowa. Electronic address:

Objective: To evaluate the accuracy of the initial diagnosis in the case of fungal infections of the orbit and identify factors that may influence patient outcomes.

Methods: An institutional review board-approved retrospective chart review was conducted across 2 large academic centres to identify cases of fungal infections involving the orbit from January 1, 1998, to November 15, 2019. Data collected included patient demographics, past medical history, examination findings, diagnosis, treatment, imaging, and outcomes. Read More

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Unique Presentation of Septic Cavernous Sinus Thrombosis and Pulmonary Embolism in the Setting of Reusable Face Covering.

Case Rep Infect Dis 2022 15;2022:3388537. Epub 2022 Apr 15.

Division of Infectious Disease, Tripler Army Medical Center, Honolulu, HI 96859, USA.

Identified in December 2019, SARS-CoV-2 quickly spread worldwide with a resultant increase in global morbidity, mortality, and economic disruption on a scale not seen since the 1918 Spanish flu. Health officials recommended universal masking to further reduce human-to-human spread of SARS-CoV-2. The state of Hawaii and the Department of Defense (DOD) adopted strict mask policies early in the pandemic and is shown to be effective at reducing transmission. Read More

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Septic cavernous sinus thrombosis after minor head trauma: A case report.

Medicine (Baltimore) 2022 Mar 11;101(10):e29057. Epub 2022 Mar 11.

Department of Neurology, Chonnam National University Medical School & Hospital, Gwangju, South Korea.

Rationale: Septic cavernous sinus thrombosis (SCST) is a rare but life-threatening condition that commonly arises from infections, including paranasal sinusitis, otitis media, and skin infection. Meanwhile, head trauma as a predisposing factor of SCST has been scarcely reported. We report a case of SCST complicated by meningitis after minor head trauma, even in the absence of identifiable fractures. Read More

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Clinical Profile of Central Nervous System Involvement in Patients with Rhino Orbital Cerebral Mucormycosis.

J Assoc Physicians India 2022 Apr;70(4):11-12

Bangalore Medical College, Kalaburgi.

Mucormycosis is life threatening fungal infection that occurs in immunocompromised patients. Patients at risk are those with poorly controlled diabetes mellitus, immunosuppressed patients such as those undergoing treatment for hematological cancer or recipients of solid organ and hematopoietic stem cell transplantation. COVID 19 infection is known to produce a state of hyper inflammation with release of various cytokines this state of immune dysfunction is associated with development of opportunistic infections, of which Mucormycosis is on the rise currently. Read More

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Clinical Profile and Long-Term Outcomes in Pediatric Cavernous Sinus Thrombosis.

Pediatr Neurol 2022 05 4;130:28-40. Epub 2022 Mar 4.

Department of Pediatrics, Section of Pediatric Neurology and Developmental Neuroscience, Baylor College of Medicine, Houston, Texas. Electronic address:

Background: Pediatric cavernous sinus thrombosis (CST) is a rare condition with limited data regarding its clinical characteristics and long-term outcomes. The objective of this study was to describe the clinical and radiologic features, diagnostic evaluation, management, and long-term prognosis and to identify clinical variables associated with long-term outcomes in pediatric CST.

Methods: A retrospective chart review of patients younger than 18 years diagnosed with a CST between 2004 and 2018 at a single center was conducted. Read More

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Radiological spectrum of invasive mucormycosis in COVID-19.

BJR Case Rep 2022 Mar 9;7(6):20210111. Epub 2022 Mar 9.

Department of Radio-diagnosis, Batra Hospital and Medical Research Centre (BHMRC), New Delhi, India.

Mucormycosis, commonly known as the "black fungus" is recently emerging as a deadly complication in COVID patients in the Indian subcontinent. A growing number of cases are being reported from all over the country, with a majority of the patients either undergoing treatment or having recovered from COVID. Here, we report three cases of multisystem mucormycosis in COVID positive patients showing, rhino-orbital, cerebral, pulmonary, and genitourinary involvement. Read More

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Methamphetamine Injection Into Face Causing Fatal Cavernous Sinus Thrombosis.

Am J Forensic Med Pathol 2022 Mar 4. Epub 2022 Mar 4.

From the Department of Pathology, Harris County Institute of Forensic Sciences Baylor Scott and White Health, Dallas, TX.

Abstract: Cavernous sinus thrombosis is a rare and often fatal condition, usually associated with infections in the head and neck region. Clinical presentation includes fever, headache, and periorbital swelling. Mortality can be high; however, prompt treatment can reduce the probability of death. Read More

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Orbital abscess: 20 years' experience at a tertiary eye care center.

Orbit 2022 Feb 23:1-8. Epub 2022 Feb 23.

Orbit, Oculoplasty, Aesthetic & Reconstructive Services, Sankara Nethralaya, Medical Research Foundation, Chennai, India.

Purpose: To study the clinical, microbiological profile and management outcomes of orbital abscess at a tertiary care center in South India.

Material And Method: In a retrospective interventional case series, we reviewed all patients diagnosed with orbital cellulitis from 2000-2020. The data analyzed included demographic profile, clinical and radiological features, microbiological profile, and management outcome. Read More

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February 2022

Cavernous Sinus Thrombosis and Blindness Complicating Dental Infection.

Cureus 2022 Jan 17;14(1):e21318. Epub 2022 Jan 17.

Ophthalmology, Kuala Lumpur General Hospital, Kuala Lumpur, MYS.

A 32-year-old gentleman with underlying hypertension presented with left eye ptosis and diplopia for two weeks. He also complained of the left eye progressive blurring of vision. One week of left-sided toothache, headache, and fever preceded these symptoms. Read More

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January 2022

When Worlds Collide: An Interesting Case of Rhinocerebral Mucormycosis Exacerbated by COVID-19 and Diabetic Ketoacidosis Complicated by Intraorbital Hematoma.

Cureus 2022 Jan 13;14(1):e21203. Epub 2022 Jan 13.

Internal Medicine, Texas Tech University Health Sciences Center El Paso, El Paso, USA.

Mucormycosis is a devastating fungal infection seen in patients who are immunosuppressed or in severe inflammatory states. Mucormycosis has been increasingly seen in the setting of the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) virus. We describe a 68-year-old male with a past medical history of uncontrolled diabetes mellitus who presented with acute vision loss and was found to have concomitant diabetic ketoacidosis (DKA) and coronavirus disease 2019 (COVID-19) infection on presentation. Read More

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January 2022

Cavernous sinus thrombosis with bilateral orbital vein involvement and diffuse ischemic retinopathy.

Arq Bras Oftalmol 2022 Feb 14. Epub 2022 Feb 14.

Department of Ophthalmology, Scheie Eye Institute, University of Pennsylvania, Philadelphia, PA, USA.

A 53-year-old man with a 3-day history of periorbital swelling and vision loss in the left eye was found to have septic cavernous sinus thrombosis with bilateral orbital vein involvement causing congestive orbitopathy. He was treated with an emergent canthotomy and cantholysis, intraocular pressure-lowering drops, antibiotics, anticoagulation, and serial examinations. Optical coherence tomography ultimately revealed diffuse ischemic destruction of both layers of the retina, which suggested occlusion of the ophthalmic artery or the short posterior ciliary arteries and central retinal artery without intracavernous internal carotid artery involvement. Read More

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February 2022

Study of Profile of Mucormycosis During the Second Wave of COVID-19 in a Tertiary Care Hospital.

Cureus 2022 Jan 9;14(1):e21054. Epub 2022 Jan 9.

Internal Medicine, Tata Main Hospital, Jamshedpur, IND.

Introduction and aim Mucormycosis is a lethal opportunistic infection caused by filamentous fungi of the family Mucoraceae (black fungus). There has been a sudden increase in the incidence of these cases during the second wave of the COVID-19 pandemic due to the immunocompromised state caused by the disease and its treatment. Early diagnosis and appropriate medical management are essential to reduce disease morbidity and mortality. Read More

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January 2022

Management of Cavernous Sinus Thrombosis Following Herpes Zoster Ophthalmicus.

Cureus 2022 Jan 8;14(1):e21036. Epub 2022 Jan 8.

Department of Neurology, University of Florida College of Medicine, Gainesville, USA.

Herpes zoster opthalmicus (HZO) is the reactivation of latent varicella zoster virus (VZV) within the ophthalmic branch of the trigeminal ganglion (V1). Common complications are postherpetic neuralgia and vasculopathy. Here, we report a rare case of a 47-year-old female presenting with HZO and aseptic cavernous sinus thrombosis (CST). Read More

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January 2022

Mucormycosis in COVID-19: A systematic review of literature.

Infez Med 2021 10;29(4):504-512. Epub 2021 Dec 10.

Department of Neurology, University of Alabama, Birmingham, USA.

Coronavirus disease 2019 (COVID-19) is an acute viral illness caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). Opportunistic infections such as mucormycosis have been reported among COVID-19 patients particularly in South Asian countries during the second wave of this pandemic. It is necessary to re-evaluate any changes in traditional risk factors associated with mucormycosis such as diabetes mellitus, organ transplant, etc in the precedent of ongoing COVID-19 pandemic. Read More

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December 2021

Successful closure of trigemino-cavernous fistula with minimally invasive approach.

BMJ Case Rep 2022 Feb 9;15(2). Epub 2022 Feb 9.

Department of Neurology, G S Neuroscience Clinic and Research Center, Patna, Bihar, India.

A male in his early teens presented with redness of the right eye following a fall. This redness was progressive and increased suddenly over the week prior to presentation. Fundus evaluation revealed an exudative retinal detachment, and a bruit was audible over the right eye. Read More

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February 2022

Mucormycosis in COVID-19 pandemic: study at tertiary hospital in India.

Eur Arch Otorhinolaryngol 2022 Jun 5;279(6):3201-3210. Epub 2022 Feb 5.

Department of ENT, GMC Miraj (Maharashtra), Miraj, India.

Aim: During the second wave of COVID-19, cases of mucormycosis were increased suddenly over a period of 3 months in Maharashtra, India. An attempt was made to study the clinical profile and risk factors associated with mucormycosis.

Materials And Methods: A retrospective descriptive study was carried out at a tertiary hospital during May 2021-July 2021. Read More

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Cavernous Sinus Thrombosis and Blindness After Simple Tooth Extraction in Patient Who Recovered From Coronavirus 2019: A Case Report.

J Oral Maxillofac Surg 2022 04 30;80(4):709-713. Epub 2021 Dec 30.

Associate Professor, Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Beni-Suef University, Beni-Suef, Egypt. Electronic address:

The pandemic Coronavirus 2019 is a disease transmitted either by droplets from a person's sneeze or cough or direct spread; also known as severe acute respiratory syndrome coronavirus-2. Although the morbidity of the disease is mainly related to respiratory distress, the associated inflammatory response can induce various coagulopathies despite an anticoagulant therapy. The authors are documenting a case of a diabetic patient who recovered from Coronavirus 2019 and is on prophylactic anticoagulant therapy after routine extraction of a maxillary second molar that progressed to unilateral cavernous sinus thrombosis and loss of vision. Read More

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Predictors of seizures in patients with cerebral venous thrombosis in the Thai population: A retrospective study.

Seizure 2022 Mar 10;96:1-5. Epub 2022 Jan 10.

Division of neurology, Department of Internal Medicine, Faculty of Medicine, Prince of Songkla University, Hat Yai, Songkhla 90110, Thailand. Electronic address:

Purpose: This study aimed to define independent factors associated with the onset of early seizure (ES) amongst patients with cerebral venous thrombosis (CVT).

Methods: This retrospective cohort study recruited patients diagnosed with CVT and hospitalised between 2002 and 2020. Demographic, clinical, and seizure characteristics; neuroimaging findings; and clinical outcomes were compared between the seizure and non-seizure groups. Read More

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Bridging the Gap between Ophthalmology and Emergency Medicine in Community-Based Emergency Departments (EDs): A Neuro-Ophthalmology Guide for ED Practitioners.

Clin Pract 2021 Dec 2;11(4):919-932. Epub 2021 Dec 2.

Department of Ophthalmology, Central Valley Eye Medical Group, Stockton, CA 95207, USA.

Coordination of care for patients with neuro-ophthalmic disorders can be very challenging in the community emergency department (ED) setting. Unlike university- or tertiary hospital-based EDs, the general ophthalmologist is often not as familiar with neuro-ophthalmology and the examination of neuro-ophthalmology patients in the acute ED setting. Embracing image capturing of the fundus, using a non-mydriatic camera, may be a game-changer for communication between ED physicians, ophthalmologists, and tele-neurologists. Read More

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December 2021

Low Fluctuation of Symptoms May Delay Diagnosis of Myasthenia Gravis: A Case Series.

Neurol Ther 2022 Mar 18;11(1):481-487. Epub 2021 Dec 18.

Neurology Department, University Emergency Hospital of Bucharest, 169 Splaiul Independentei, 050098, Bucharest, Romania.

Introduction: Myasthenia gravis is an autoimmune disorder affecting neuromuscular transmission, and its hallmark is fluctuating muscular weakness affecting the ocular, bulbar, respiratory, or limb muscles. Our objective is to highlight the difficulties encountered in diagnosing this disorder in patients lacking this characteristic phenomenon.

Methods: Three cases of patients presenting with progressive weakness of bulbar and ocular muscles, in whom a lack of fluctuation delayed the diagnosis of myasthenia gravis, are described. Read More

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Clinico-Radiological-Pathological Correlation of Visual Loss in COVID-Associated Rhino-Orbito-Cerebral Mucormycosis.

Ophthalmic Plast Reconstr Surg 2022 May-Jun 01;38(3):242-249. Epub 2022 May 11.

Department of Radiodiagnosis, Maulana Azad Medical College, New Delhi, India.

Purpose: To correlate the clinical, radiological, and histopathological features in Covid-associated Rhino-orbito-cerebral mucormycosis cases presenting with acute visual loss.

Design: Cross-sectional study.

Methods: Covid-associated Rhino-orbito-cerebral mucormycosis cases with unilateral visual loss, planned for exenteration, underwent orbital and ophthalmological ocular examination. Read More

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Mucormycosis with extensive cranial nerve involvement as the first presentation of diabetes mellitus: A case report.

Qatar Med J 2021 30;2021(3):61. Epub 2021 Oct 30.

Primary Health Care Corporation, Doha, Qatar.

Mucormycosis, a rare fungal infection, mainly affects individuals with diabetes mellitus and those who were immunocompromised and has a high mortality rate. Its most common presentation is similar to that of acute bacterial sinusitis with symptoms of nasal congestion, headache, and fever. The involvement of multiple cranial nerves in mucormycosis was rarely reported in the literature and indicates severe disease. Read More

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October 2021

Sinogenic Orbital Complications.

Dtsch Arztebl Int 2022 Jan 21(Forthcoming). Epub 2022 Jan 21.

Background: The term "orbital complication" does not designate an independent nosological entity, but is rather a collective designation for diseases or disease effects that involve the orbit and its internal structures by extension from outside. In general, their most prominent manifestation is swelling of the orbital soft tissues, usually unilaterally. The incidence of sinogenic orbital complications is approximately 1. Read More

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January 2022

Superior Ophthalmic Vein Thrombosis Induced by Orbital Cellulitis: An Ophthalmic Emergency.

Cureus 2021 Oct 25;13(10):e19038. Epub 2021 Oct 25.

Internal Medicine, New York-Presbyterian Brooklyn Methodist Hospital, Brooklyn, USA.

Superior ophthalmic vein thrombosis (SOVT) is a rare ophthalmologic emergency. The most common etiologies include infection, trauma, inflammation, and malignancy, as well as thyroid-related orbitopathy. Early identification and timely intervention can lead to a significant decrease in complications that include cavernous sinus thrombosis (CST), vision loss, and death. Read More

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October 2021