1,441 results match your criteria Cavernous Sinus Thrombosis

Cavernous sinus thrombosis: a late complication of head and neck surgery.

BMJ Case Rep 2021 Feb 4;14(2). Epub 2021 Feb 4.

Surgical Oncology, All India Institute of Medical Sciences, New Delhi, India.

Cavernous sinus thrombosis is a rare but fatal condition arising due to various infectious and noninfectious causes. Although its incidence is very low in the setting of head and neck surgery, including radical neck dissection, a high index of suspicion with prompt treatment is the key to a successful outcome. We report a case of a 50-year-old woman with a chondrosarcoma of left lower alveolobuccal complex who underwent en bloc tumour resection with infratemporal fossa clearance and left modified radical neck dissection. Read More

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February 2021

Cavernous Sinus Thrombosis related to Orbital Cellulitis Serious Complication to Prevent: a case report and literature review.

Ann Med Surg (Lond) 2021 Feb 18;62:179-181. Epub 2021 Jan 18.

Faculty of Medicine and Pharmacy, Hassan II University of Casablanca, B.P 5696, Casablanca, Morocco.

Introduction: The authors report a case which aims to underline the importance of multidisciplinary management and rapid diagnosis of orbital cellulitis, for an adequate treatment of ocular damages and related complications, to prevent serious and permanent sequelae and avoid a fatal prognosis.

Presentation Of Case: A 61-year-old female reported to the oral and maxillofacial surgery department after she was dragged around for two months. She presented with a right facial swelling and orbital apex syndrome including proptosis, ophthalmoplegia and ptosis. Read More

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February 2021

Orbital Apex Syndrome: A Clinico-anatomical Diagnosis.

J Pediatr Neurosci 2020 Jul-Sep;15(3):336-337. Epub 2020 Nov 6.

Division of Child Neurology, Department of Pediatrics, All India Institute of Medical Sciences, New Delhi, India.

An 8-month-old girl presented with fever, restricted left eye movements and increasing proptosis for 8 days. On examination she had left orbital cellulitis, relative afferent pupillary defect and ophthalmoplegia. Contrast-enhanced magnetic resonance imaging (MRI) brain with orbits revealed orbital apex syndrome (OAS) with cavernous sinus thrombosis. Read More

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November 2020

Etiology, localization of the lesion, and prognosis for patients firstly diagnosed in ophthalmology department with oculomotor nerve palsy.

Zhong Nan Da Xue Xue Bao Yi Xue Ban 2020 Dec;45(12):1425-1430

Department of Ophthalmology, First Medical Center of PLA General Hospital, Beijing 100039, China.

Objectives: Oculomotor nerve palsy is a kind of disease with many causes, showing eye movement disorders, abnormal eyelid position, and/or damage of the pupil. The etiology of oculomotor nerve palsy in different departments is different. The study discussed the etiology, localization of the lesion, and prognosis for oculomotor nerve palsy firstly diagnosed in department of ophthalmology. Read More

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December 2020

Bilateral cavernous sinus and left dural sigmoid sinus thrombosis associated with extreme exertion: a case report.

Arq Bras Oftalmol 2021 Jan-Feb;84(1):83-86

Department of Ophthalmology, School of Medical Sciences, Universiti Sains Malaysia, Kerian, Kelantan, Malaysia.

Septic cavernous sinus thrombosis is a rare but often debilitating and potentially fatal disease. We describe a case of bilateral orbital cellulitis with rapidly progressing cavernous sinus thrombosis and left sigmoidal sinus thrombosis in an immunocompetent 20-year-old military man who had undergone intensive physical training. The patient presented with rapid painful swollen left eye for 2 days. Read More

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February 2021

Risk factors of orbital complications in outpatients presenting with severe rhinosinusitis: A case-control study.

Clin Otolaryngol 2021 May 24;46(3):587-593. Epub 2021 Jan 24.

Department of Otolaryngology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

Objectives: We assessed associations of potential factors with orbital complications in acute rhinosinusitis (ARS) patients.

Design: An unmatched case-control study.

Setting: A tertiary referral hospital in Thailand. Read More

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A Unique Radiologic Case of Optic Nerve Infarction in a Patient With Mucormycosis.

J Neuroophthalmol 2021 Jan 11. Epub 2021 Jan 11.

Ruiz Department of Ophthalmology and Visual Science (ALC, THD, KR, O-OA), McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth), Houston, Texas; Robert Cizik Eye Clinic (ALC, THD, KR, O-OA), Houston, Texas; Department of Diagnostic and Interventional Imaging (EPS), McGovern Medical School at UTHealth, Houston, Texas; and Departments of Pathology (MBB) and Neurology (O-OA), McGovern Medical School at UTHealth, Houston, Texas.

Abstract: This is a rare presentation of a unilateral optic nerve infarction of the left eye caused by mucormycosis in a 51-year-old man with poorly controlled Type 2 diabetes. Diffusion-weighted MRI of the orbit demonstrated extensive infarction of the left optic nerve with ipsilateral cavernous sinus thrombosis and periorbital adnexal inflammation. Left orbital exenteration and sinus debridement were performed, and mucormycosis involving the optic nerve sheath was confirmed on histopathology. Read More

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January 2021

Skull base osteomyelitis with secondary cavernous sinus thrombosis: a rare presentation of an animate foreign body in the ear.

BMJ Case Rep 2021 Jan 11;14(1). Epub 2021 Jan 11.

Department of ENT-Otology, Neurotology & Cochlear Implant Unit, Christian Medical College and Hospital Vellore, Vellore, India.

A 42-year-old woman presented with fever, left ear pain, restricted mouth opening, difficulty in swallowing and inability to open her left eyelid for a period of 10 days. She was treated with antibiotics for the same at a local medical facility; however, a sudden decrease in her left eye vision prompted her to visit our tertiary centre. Her history was insignificant except for having multiple left ear syringing for an insect removal 10 days before onset of her current symptoms. Read More

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January 2021

Spontaneous Abscess of the Posterior Nasal Septum: An Unusual Cause of Nasal Obstruction in Children.

Ann Otol Rhinol Laryngol 2021 Aug 9;130(8):966-969. Epub 2021 Jan 9.

Unit of Otorhinolaryngology-Head and Neck Surgery, University of Brescia, Brescia, Italy.

Introduction: Nasal septal abscess is a rare disorder in pediatric patients and is mostly diagnosed as a complication of trauma or secondary to dental or sinonasal infection.

Case Presentation: A 10-year-old girl presented with acute nasal obstruction, otalgia, and headache. Medical history was negative; physical examination and anterior rhinoscopy did not reveal signs of acute rhinosinusitis or septal abscess. Read More

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Bilateral cavernous sinus thrombosis complicating acute unilateral pansinusitis in a 15-year-old boy.

BMJ Case Rep 2020 Dec 22;13(12). Epub 2020 Dec 22.

Otolaryngology, University Hospital Crosshouse, Kilmarnock, UK.

Cavernous sinus thrombosis (CST) is a rare and potentially fatal complication of acute sinusitis. Timely diagnosis and management is, therefore, essential in preventing death and neurological disability. Here, we describe the case of a paediatric patient with bilateral CST secondary to acute unilateral pansinusitis that presented with rapidly progressing bilateral periorbital oedema. Read More

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December 2020

The diagnostic dilemma of a pregnant woman presenting with an isolated sixth nerve palsy: A case report.

Obstet Med 2020 Dec 31;13(4):195-197. Epub 2019 Jan 31.

Department of Radio-Diagnosis, Jawaharlal Institute of Post-graduate Medical Education & Research (JIPMER), Puducherry, India.

Pregnant women presenting with isolated cranial palsies are uncommon. Isolated sixth nerve (abducens nerve) palsy can occur for a variety of reasons and neuroimaging is often performed to identify an underlying cause. We report a case of a woman in her third pregnancy with preeclampsia who presented with an isolated sixth nerve palsy. Read More

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December 2020

[Co-existence of Guillain-Barré syndrome and Behcet syndrome: A case report].

C Yu C Li Y Y Fan Y Xu

Beijing Da Xue Xue Bao Yi Xue Ban 2020 Dec;52(6):1146-1149

Department of Neurology, Peking University People's Hospital, Beijing 100044, China.

A 40-year-old male patient was referred to our department with complains of recurrent oral ulcer for more than 20 years and vulvar ulcer for more than 10 years. He presented with a 3-month history of right external ophthalmoplegia. More than 10 days ago, the patient received ganglioside infusion. Read More

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December 2020

Herpes zoster in the ophthalmic branch of the trigeminal ganglia obscuring cavernous sinus thrombosis due to subsp. - A case report.

Anesth Pain Med (Seoul) 2020 Apr 29;15(2):205-208. Epub 2020 Apr 29.

Department of Anesthesiology and Pain Medicine, Presbyterian Medical Center, Jeonju, Korea.

Background: Herpes zoster ophthalmicus (HZO) is an infectious disease that results from the reactivation of latent varicella zoster virus in the ophthalmic branch of the trigeminal ganglia. HZO manifests with herpes zoster-like symptoms such as rash with or without signs of ocular involvement. Cavernous sinus thrombosis (CST) is a life-threatening condition accompanied by signs and symptoms involving the eyes and the cranial nerves. Read More

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Cavernous sinus thrombosis in a COVID-19 patient: A case report.

Radiol Case Rep 2021 Mar 9;16(3):480-482. Epub 2020 Dec 9.

Radiology department of CHU HASSAN II de Fez, Morocco, Faculty of medecine Fez, Universitý Sidi Mohamed Ben Abdellah, Fez, Morocco.

Coronavirus disease 2019 (COVID-19) is an emerged pandemic disease caused by a new coronavirus known as SARS-CoV-2 (severe acute respiratory syndrome-coronavirus-2). Initially the mortality of this infection are related to severe acute respiratory distress syndrome, but several publications also showed that this infection caused an inflammatory response with severe systemic complications [1]. Venous thromboembolism has been shown to be an important cause of morbidity and mortality in patients with COVID-19, both in the general inpatient and in the intensive care unit (ICU) setting, and even in patients receiving therapeutic anticoagulation [2]. Read More

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Cavernous sinus thrombosis after follow-up cerebral angiography.

Porto Biomed J 2020 Nov-Dec;5(6):e097. Epub 2020 Nov 24.

Neurology Department, Centro Hospitalar Universitário de São João, E.P.E; Department of Clinical Neurosciences and Mental Health, Faculty of Medicine, Porto University (FMUP).

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November 2020

Neurovascular disease and syndromes: Diagnosis and therapy in children.

Gary M Nesbit

Handb Clin Neurol 2021 ;176:305-323

Dotter Department of Interventional Radiology, Oregon Health and Science University, Portland, OR, United States. Electronic address:

The pediatric neurovascular disease runs the chronologic spectrum with dramatic changes in the presentation, evaluation, and treatment from the prenatal, perinatal, and infant periods through childhood and adolescence. These diseases are often dynamic throughout this period and the dynamic continues throughout life. There are four major categories: high-flow arteriovenous shunting lesions, arterial aneurysms, low-flow vascular lesions, and vascular occlusive disease. Read More

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Images of the month: Cavernous sinus venous thrombosis secondary to maxillary sinusitis: An unusual cause of diplopia and headache.

Clin Med (Lond) 2020 11;20(6):e271-e272

St George's University Hospitals NHS Foundation Trust, London, UK and St George's, University of London, London, UK.

Cavernous sinus venous thrombosis is an uncommon condition associated with high mortality rates if not recognised early. Symptoms include headache, visual loss, ophthalmoplegia, altered consciousness, proptosis and periorbital oedema. High-quality imaging is critical in early diagnosis and successful management. Read More

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November 2020

Panophthalmitis and Orbital Inflammation with Cavernous Sinus Thrombosis Following Cataract Surgery.

Int Med Case Rep J 2020 3;13:569-572. Epub 2020 Nov 3.

Ophthalmology Department, Westmead Hospital, Sydney, NSW, Australia.

Background: Panophthalmitis is a severe inflammation of the globe that can result as a rare complication of ophthalmic surgery. In severe cases, it may also be associated with orbital inflammation and cavernous sinus thrombosis.

Purpose: This case demonstrates a rare and life-threatening post-operative complication of cataract surgery. Read More

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November 2020

Internal Jugular Vein and Cerebral Venous Sinus Infective Thrombophlebitis Detected With 99mTc-HMPAO White Blood Cell Scintigraphy.

Clin Nucl Med 2021 Feb;46(2):e112-e113

Nuclear Medicine, Western University, London.

Abstract: A 35-year-old man with a history of renal transplant, congenital cystinosis, and diabetes was admitted to the hospital with fever, bilateral parotid gland swelling, and acute renal failure. He had 99mTc-HMPAO-WBC (99mTc-hexamethylpropyleneamineoxime white blood cell) imaging for the evaluation of possible parotitis. There was intense radiopharmaceutical uptake along the right internal jugular vein extending to the right sigmoid and transverse and superior sagittal sinuses, suggestive of infective thrombophlebitis or Lemierre syndrome. Read More

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February 2021

Diagnostic difficulties in a patient with multiple sclerosis who presents with cranial nerve palsies: an unusual complication of dental work.

BMJ Case Rep 2020 Oct 30;13(10). Epub 2020 Oct 30.

NHS Lanarkshire, Bothwell, UK.

A woman in her 60s with multiple sclerosis (MS) presented with right-sided ptosis, right sixth nerve palsy, right facial paraesthesia and signs of sepsis. She had a recent diagnosis of a dental abscess. Investigations revealed a right submasseter abscess leading to bacterial meningitis () and a cavernous sinus thrombosis. Read More

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October 2020


Ulster Med J 2020 09 21;89(2):131-132. Epub 2020 Oct 21.

Consultant Department of Diabetes & Endocrinology, Russells Hall hospital, Dudley Group NHS Foundation Trust.

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September 2020

Carotid-cavernous fistula from the perspective of an ophthalmologist A Review.

Čmelo Jozef

Cesk Slov Oftalmol 2020 ;1(Ahead of print):1-8

Carotid-cavernous fistula (CCF) is an abnormal communication - vascular connection between arteries and veins in the cavernous sinus. Classification according to etiology is traumatic vs spontaneous. According to blood flow rate per high flow vs low flow fistula. Read More

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November 2020

Efficiency of Endovascular Therapy for Bilateral Cavernous Sinus Dural Arteriovenous Fistula.

World Neurosurg 2021 02 10;146:e53-e66. Epub 2020 Oct 10.

Division of Diagnostic Radiology, Department of Radiology, Faculty of Medicine Siriraj Hospital, Mahidol University, Bangkok, Thailand.

Background: The principles of endovascular treatment of bilateral cavernous sinus dural arteriovenous fistula (CS-dAVF) are not well established because of the complexity in the number of fistula tracts and their behavior, which seems to be more aggressive. We aimed to determine an efficient technique for endovascular treatment of bilateral CS-dAVF and the associated factors to achieve good clinical and angiographic outcomes.

Methods: The data were analyzed from 165 consecutive patients diagnosed with CS-dAVF from January 2005 to September 2018. Read More

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February 2021

Paediatric periorbital cellulitis: A 10-year retrospective case series review.

J Paediatr Child Health 2021 Feb 28;57(2):227-233. Epub 2020 Sep 28.

Ear, Nose and Throat Department, Norfolk and Norwich University Hospital, Norwich, United Kingdom.

Aim: To identify the predictors of poor outcome and need for surgical management in paediatric patients with periorbital cellulitis. To assess the adherence to local guidelines in the management of periorbital cellulitis.

Methods: Retrospective descriptive analysis of clinical, laboratory and radiological characteristics of 175 paediatric periorbital cellulitis presentations at a UK teaching hospital over a 10-year period. Read More

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February 2021

Retinal and Optic Nerve Deformations Due to Orbital Versus Intracranial Venous Hypertension.

J Neuroophthalmol 2020 Sep 11. Epub 2020 Sep 11.

Departments of Neurology, Ophthalmology, and Neurosurgery (MJK), New York Eye and Ear Infirmary and Icahn School of Medicine at Mount Sinai, New York, New York; and Department of Ophthalmology (PSS), State University of New York at Stony Brook, Stony Brook, New York.

Introduction: Abnormal forces around the optic nerve head (ONH) due to orbital diseases, intracranial hypertension (IH), glaucoma, and space travel, are associated with alterations of the ONH shape. Elevated cerebral and ophthalmic venous pressure can contribute to stress and strain on the ONH and peripapillary retina. We hypothesize that IH and elevated ophthalmic venous pressure without IH cause different ONH and retinal changes. Read More

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September 2020

Cerebral Venous Sinus Thrombosis in Women: Subgroup Analysis of the VENOST Study.

Stroke Res Treat 2020 1;2020:8610903. Epub 2020 Sep 1.

Antalya Research and Training Hospital, Clinic of Neurology, Antalya, Turkey.

Background: Early diagnosis of cerebral venous sinus thrombosis (CVST) associated with reproductive health-related risk factors (RHRF) including pregnancy, puerperium, and oral contraceptive (OC) use can prevent severe neurological sequelae; thus, the symptoms must be documented in detail for each group.

Methods: Out of 1144 patients with CVST, a total of 777 women were enrolled from a multicenter for the study of cerebral venous sinus thrombosis (VENOST). Demographic, biochemical, clinical, and radiological aspects were compared for 324 cases with RHRF and 453 cases without RHRF. Read More

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September 2020

Spectrum of Orbital Cellulitis on Magnetic Resonance Imaging.

Cureus 2020 Aug 11;12(8):e9663. Epub 2020 Aug 11.

Radiology, Bharati Vidyapeeth Hospital, Pune, IND.

Introduction Orbital infection is an ophthalmological emergency as it can lead to blindness and intracranial spread. Imaging is needed to determine the extent of the infection, to localize an abscess, and for surgical planning. The role of magnetic resonance imaging (MRI) is well established in the evaluation of orbital pathologies, including orbital cellulitis and abscess, mainly due to its ability to evaluate early intracranial involvement. Read More

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A Challenging Case of Lemierre's Syndrome With Central Nervous System Involvement and a Comprehensive Review.

Cureus 2020 Aug 30;12(8):e10131. Epub 2020 Aug 30.

Internal Medicine, Medical College of Wisconsin, Wauwatosa, USA.

Lemierre's syndrome (LS) is a complex medical condition that is characterized by an acute oropharyngeal infection leading to thrombophlebitis of the internal jugular vein and an eventual metastatic spread to distant vital organs. This metastatic spread is from septic emboli and is most frequently seen in the lungs, kidneys, and large joints. Central nervous system (CNS) involvement in LS is extremely rare, and only a few cases of CNS involvement have been reported in the literature. Read More

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Cerebral Venous Thrombosis: A Comprehensive Review.

Eur Neurol 2020 2;83(4):369-379. Epub 2020 Sep 2.

Columbia University Medical Center, New York, New York, USA.

Background: Cerebral sinus venous thrombosis (CSVT) is a relatively rare, potentially fatal neurological condition that can be frequently overlooked due to the vague nature of its clinical and radiological presentation. A literature search on PubMed using the keyword "Cerebral sinus venous thrombosis" was performed. We searched for the epidemiology, risk factors, pathophysiology, clinical features, diagnosis, and treatment of CSVT. Read More

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February 2021

Allergic fungal sinusitis masquerading as cavernous sinus thrombosis.

J Surg Case Rep 2020 Aug 24;2020(8):rjaa233. Epub 2020 Aug 24.

Department of Ophthalmology, Loma Linda University Medical School, Loma Linda, California.

Allergic fungal sinusitis (AFS), a noninvasive form of fungal sinusitis, is rarely seen in immunocompetent patients. Involvement of sphenoid sinus can result in proptosis and loss of vision. We report AFS masquerading as posterior cavernous sinus syndrome. Read More

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