758 results match your criteria Cauda Equina and Conus Medullaris Syndromes


An Asymptomatic Case of Radiologically Active Neurocysticercosis.

Cureus 2020 May 21;12(5):e8219. Epub 2020 May 21.

Internal Medicine, Midland Memorial Hospital, Midland, USA.

The case describes an 82-year-old right-handed Hispanic male with multiple chronic comorbidities complaining of upper and lower extremity weakness as well as paresthesias that had been worsening over the last two weeks. He had bilateral upper and lower extremity weakness that was worse on the right and he complained of not being able to walk on his own with several falls preceding admission because of this. There were no overt signs of spinal cord compression or cauda equina syndrome. Read More

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http://dx.doi.org/10.7759/cureus.8219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7306638PMC

[Malignant Spinal Cord Compression].

Gan To Kagaku Ryoho 2020 Jun;47(6):875-880

Dept. of Medical Oncology, Toranomon Hospital.

Malignant spinal cord compression(MSCC)is defined as a compression of the spinal cord or cauda equina with neuropathy caused by tumor spreading to the vertebral body. The common symptoms of MSCC are back pain, neck pain, muscle weakness, sensory reduction, bladder and rectal disturbance. The risk of MSCC is relatively high in patients with lung cancer, breast cancer, and prostate cancer. Read More

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Expression of Nogo-A in dorsal root ganglion in rats with cauda equina injury.

Biochem Biophys Res Commun 2020 Jun 28;527(1):131-137. Epub 2020 Apr 28.

Department of Orthopedic Surgery, Spine Center, Changzheng Hospital, Second Military Medical University, No.415 Fengyang Road, Shanghai, 200003, People's Republic of China. Electronic address:

Objective: To investigate the expression of Nogo-A in dorsal root ganglion (DRG) in rats with cauda equina injury and the therapeutic effects of blocking Nogo-A and its receptor.

Methods And Materials: Fifty-eight male Sprague-Dawley rats were divided randomly into either the sham operation group (n = 24) or the cauda equina compression (CEC) control group (n = 34). Behavioral, histological, and terminal deoxynucleotidyl transferase dUTP nick end labeling (TUNEL) analyses were conducted to assess the establishment of the model. Read More

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http://dx.doi.org/10.1016/j.bbrc.2020.04.094DOI Listing

Spinal Epidural Hematoma After Attempted Catheter Thrombectomy of a Large Iliofemoral Deep Venous Thrombosis: A Case Report.

R I Med J (2013) 2020 May 1;103(4):52-54. Epub 2020 May 1.

Department of Neurosurgery, The Warren Alpert Medical School of Brown University, Providence.

The authors report the case of an 82-year-old woman with a spinal epidural hematoma following attempted catheter-directed thrombolysis of a large femoral- popliteal deep venous thrombosis. The patient rapidly developed acute motor and sensory paralysis below the level of T7 within hours of the thrombectomy procedure. Computed tomography imaging revealed that the catheter had perforated the wall of the right inferior vena cava and magnetic resonance imaging subsequently demonstrated an extensive T1-S1 dorsal epidural hematoma with compression of the thoracic spinal cord, conus medullaris, and cauda equina. Read More

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Metastatic spinal cord compression.

Br J Hosp Med (Lond) 2020 Apr;81(4):1-10

Department of Trauma and Orthopaedic Surgery, East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust, Redhill, UK.

Metastatic spinal cord compression is compression of the spinal cord or cauda equina as a result of metastatic deposits in the spinal column. It affects approximately 4000 cases per year in England and Wales. Prompt identification and treatment of metastatic spinal cord compression is necessary to prevent irreversible neurological injury, treat pain and maintain patients' mobility, function and independence. Read More

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http://dx.doi.org/10.12968/hmed.2019.0399DOI Listing

Posterior and anterior epidural and intradural migration of the sequestered intervertebral disc: Three cases and review of the literature.

J Spinal Cord Med 2020 Mar 4:1-6. Epub 2020 Mar 4.

Department of Radiology, Miyazaki Konan Hospital, Miyazaki, Japan.

Dorsal migration of the sequestered lumbar intervertebral disc is an unusual and underrecognized pattern of lumbar disc herniation associated with pain and neurological deficit. Three patients presented with lower limb- and low back pain. MR imaging showed intracanalicular mass lesions with compression of the spinal cord and allowed precise localization of lesions in the extradural or intradural space. Read More

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http://dx.doi.org/10.1080/10790268.2020.1730110DOI Listing

Full Endoscopic Lumbar Diskectomy for Lumbar Disk Herniation in the Presence of a Low-Lying Cord.

World Neurosurg 2020 May 19;137:367-371. Epub 2020 Feb 19.

Department of Orthopedic Surgery, Kaohsiung Chang Gung Memorial Hospital and Chang Gung University College of Medicine, Kaohsiung, Taiwan. Electronic address:

Background: The distal extent of the spinal cord is most often at the level of the L1 or L2 vertebral body. In rare cases, a low-lying cord extends more distally. In this scenario, pathology that normally causes radiculopathy may cause myelopathy due to compression of the cord rather than nerve roots of the cauda equina. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.02.042DOI Listing

Traumatic intradural ruptured lumbar disc with a spinal compression fracture: A case report.

Medicine (Baltimore) 2020 Feb;99(7):e19037

Department of Neurosurgery, Chonnam National University Hospital and Medical School, Gwangju, Republic of Korea.

Rationale: We present a rare case of a traumatic intradural ruptured disc associated with a mild vertebral body compression fracture along with a review of the relevant medical literature. An intradural ruptured disc often occurs due to chronic degenerative diseases and is rarely due to trauma. It can cause irreversible neurological complications if the appropriate treatment is not planned. Read More

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http://dx.doi.org/10.1097/MD.0000000000019037DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7035050PMC
February 2020

Two cases of paralysis secondary to aneurysmal bone cysts with complete neurologic recovery.

Spine Deform 2020 Apr 11;8(2):339-344. Epub 2020 Feb 11.

Children's Orthopaedic Center, Children's Hospital Los Angeles, 4650 Sunset Blvd, MS#69, Los Angeles, CA, 90027, USA.

Design: Case report (retrospective).

Objective: These two cases of paralysis secondary to aneurysmal bone cysts (ABCs) demonstrated complete neurologic recovery following decompression and posterior spinal fusion. Although neurologic injury from ABCs has been described, information about the prognosis in the pediatric population is limited. Read More

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http://dx.doi.org/10.1007/s43390-019-00023-1DOI Listing

Spinal Sparganosis Coexisting with Acquired Arteriovenous Fistula of the Filum Terminale.

World Neurosurg 2020 Apr 26;136:341-347. Epub 2020 Jan 26.

Department of Radiology, Bumrungrad International Hospital, Bangkok, Thailand.

Background: Spinal sparganosis associated with filum terminale arteriovenous fistula (FTAVF) has not been reported in the literature. In previous studies, these 2 rare diseases were usually reported separately. We report the first case of spinal sparganosis with concomitant FTAVF. Read More

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http://dx.doi.org/10.1016/j.wneu.2020.01.132DOI Listing
April 2020
2.417 Impact Factor

Progressive myelopathy associated with spinal epidural lipomatosis in three non-obese patients with type 1 diabetes mellitus.

J Neurol Sci 2020 Apr 16;411:116688. Epub 2020 Jan 16.

Department of Neurology, Multiple Sclerosis Comprehensive Care Center, NYU Langone Medical Center, New York, NY, United States of America.

Background: Spinal epidural lipomatosis (SEL) is a rare condition defined as pathological overgrowth of the normally present epidural fat within the spinal canal. SEL is associated with Cushing disease, obesity and chronic corticosteroid therapy. Diabetes mellitus type 1 (DM1) has not known to be a risk factor for SEL. Read More

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http://dx.doi.org/10.1016/j.jns.2020.116688DOI Listing

Effect of Single-Fraction vs Multifraction Radiotherapy on Ambulatory Status Among Patients With Spinal Canal Compression From Metastatic Cancer: The SCORAD Randomized Clinical Trial.

JAMA 2019 12;322(21):2084-2094

CRUK & UCL Cancer Trials Centre, London, United Kingdom.

Importance: Malignant spinal canal compression, a major complication of metastatic cancer, is managed with radiotherapy to maintain mobility and relieve pain, although there is no standard radiotherapy regimen.

Objective: To evaluate whether single-fraction radiotherapy is noninferior to 5 fractions of radiotherapy.

Design, Setting, And Participants: Multicenter noninferiority randomized clinical trial conducted in 42 UK and 5 Australian radiotherapy centers. Read More

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http://dx.doi.org/10.1001/jama.2019.17913DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6902166PMC
December 2019

Pure Conus Medullaris Syndrome without Lower Extremity Involvement Caused by Intradural Disc Herniation at L1/2: A Case Report.

Authors:
Tetsuji Inoue

Spine Surg Relat Res 2019 19;3(4):392-395. Epub 2018 Oct 19.

Department of Orthopaedic Surgery, Minamata City General Hospital and Medical Center, Minamata, Japan.

Introduction: Conus medullaris syndrome (CMS) is a rare pathology. The conus medullaris is located at the end of the spinal cord and continues to the cauda equina. Conus medullaris lesions can cause variable symptoms and neurological deficits, usually involving the lower extremities; CMS that does not affect the lower limbs is extremely rare. Read More

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http://dx.doi.org/10.22603/ssrr.2018-0032DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834459PMC
October 2018

Alteration of the lysophosphatidic acid and its precursor lysophosphatidylcholine levels in spinal cord stenosis: A study using a rat cauda equina compression model.

Sci Rep 2019 11 12;9(1):16578. Epub 2019 Nov 12.

Department of Clinical Laboratory Medicine, The University of Tokyo, Tokyo, Japan.

Cauda equina compression (CEC) is a major cause of neurogenic claudication and progresses to neuropathic pain (NP). A lipid mediator, lysophosphatidic acid (LPA), is known to induce NP via the LPA receptor. To know a possible mechanism of LPA production in neurogenic claudication, we determined the levels of LPA, lysophosphatidylcholine (LPC) and LPA-producing enzyme autotaxin (ATX), in the cerebrospinal fluid (CSF) and spinal cord (SC) using a CEC as a possible model of neurogenic claudication. Read More

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http://dx.doi.org/10.1038/s41598-019-52999-5DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6851136PMC
November 2019

Mini-Open Lateral Corpectomy for Thoracolumbar Junction Lesions.

Oper Neurosurg (Hagerstown) 2020 Jun;18(6):640-647

Department of Neurological Surgery, University of Virginia, Charlottesville, Virginia.

Background: Neoplastic, traumatic, infectious, and degenerative pathologies affecting the thoracolumbar junction pose a unique challenge to spine surgeons. Posterior or anterior approaches have traditionally been utilized to treat these lesions. Although minimally invasive surgeries through a lateral approach to the thoracic or lumbar spine have gained popularity, lateral access to the thoracolumbar junction remains technically challenging due to the overlying diaphragm positioned at the interface of the peritoneum and pleura. Read More

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http://dx.doi.org/10.1093/ons/opz298DOI Listing
June 2020
1 Read

Performance of On-Call Radiology Residents in Interpreting Total Spine MRI Studies for the Detection of Spinal Cord Compression or Cauda Equina Compression.

AJR Am J Roentgenol 2019 12 25;213(6):1341-1347. Epub 2019 Sep 25.

Department of Radiology, Beth Israel Deaconess Medical Center, Harvard Medical School, WCB90, 330 Brookline Ave, Boston, MA 02215.

Accurate diagnosis of spinal cord compression (SCC) or cauda equina compression (CEC) is important in the emergency setting so management decisions may be made promptly. The purpose of this study is to evaluate the performance of on-call radiology residents in interpreting total spine MRI studies for the detection of SCC or CEC. On-call radiology residents' preliminary interpretation of total spine MRI studies performed over a period of two and half years were evaluated. Read More

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http://dx.doi.org/10.2214/AJR.19.21505DOI Listing
December 2019
2 Reads

Multiple bone metastases: what the palliative care specialist should know about the potential, limitations and practical aspects of radiation therapy.

Ann Palliat Med 2020 May 8;9(3):1307-1313. Epub 2019 Aug 8.

Department of Radiation Oncology, Odette Cancer Centre, University of Toronto, Toronto, ON, Canada.

Bone metastases represent a significant health care problem in the cancer population. The most common symptom for bone metastases is pain. Bone metastases may also cause pathologic fracture, spinal cord compression, cauda equina compression and serum calcium disorders. Read More

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http://dx.doi.org/10.21037/apm.2019.07.09DOI Listing
May 2020
1 Read

Correction of Adolescent Idiopathic Scoliosis Using a Convex Pedicle Screw Technique: A Novel Technique for Deformity Correction.

JBJS Essent Surg Tech 2019 Mar 13;9(1):e9. Epub 2019 Mar 13.

Scottish National Spine Deformity Centre, Royal Hospital for Sick Children, Edinburgh, United Kingdom.

Background: We describe our convex segmental pedicle screw technique for the treatment of adolescent idiopathic scoliosis. We developed this technique to achieve optimum 3-dimensional deformity correction while reducing the surgical risks of an inherently dangerous procedure.

Description: The surgery involves a wide posterior subperiosteal exposure across the deformity levels to the tips of the transverse processes. Read More

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http://dx.doi.org/10.2106/JBJS.ST.18.00009DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6635136PMC
March 2019
3 Reads

Low Back Pain in the Emergency Department: Prevalence of Serious Spinal Pathologies and Diagnostic Accuracy of Red Flags.

Am J Med 2020 01 3;133(1):60-72.e14. Epub 2019 Jul 3.

Department of Internal Medicine, University Hospital Bern, Bern, Switzerland.

Background: Very little evidence is available on the prevalence of serious spinal pathologies and the diagnostic accuracy of red flags in patients presenting to the emergency department (ED). This systematic review aims to investigate the prevalence of serious spinal pathologies and the diagnostic accuracy of red flags in patients presenting with low back pain to the ED.

Methods: We systematically searched MEDLINE, PUBMED, EMBASE, Cochrane Library, and SCOPUS from inception to January 2019. Read More

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http://dx.doi.org/10.1016/j.amjmed.2019.06.005DOI Listing
January 2020
2 Reads

Arteriovenous Fistula of the Filum Terminale: A Case Report and Review of the Literature.

World Neurosurg 2019 Oct 26;130:42-49. Epub 2019 Jun 26.

Department of Neurological Surgery, Tulane University School of Medicine, New Orleans, Louisiana, USA. Electronic address:

Background: Fistulas of the filum terminale are rare lesions that result from a fistulous connection between the artery and vein of the filum terminale. These lesions often present as progressive thoracic myelopathy secondary to venous hypertension that is transmitted to the coronal venous plexus of the spinal cord. Frequently, filum fistulas will be associated with lumbar stenosis and likely form as a result of chronic inflammation and compression. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.06.136DOI Listing
October 2019
5 Reads
2.417 Impact Factor

Paraganglioma of the Lumbar Spine: A case report and literature review.

Neurochirurgie 2019 Dec 25;65(6):387-392. Epub 2019 Jun 25.

Department of Neurosurgery, Western General Hospital, Crewe Road South, Edinburgh, EH4 2XU, UK.

Introduction: Lumbar paragangliomas are rare, vascular, neuroendocrine tumors. They are notoriously difficult to diagnose radiologically and can prove challenging to manage intraoperatively, if capable of catecholamine secretion.

Case Report: We report the case of a 45-year-old man, who presented with a lumbar spinal paraganglioma. Read More

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http://dx.doi.org/10.1016/j.neuchi.2019.05.010DOI Listing
December 2019
5 Reads

Malignant spinal cord compression.

J R Coll Physicians Edinb 2019 Jun;49(2):151-156

Aberdeen Royal Infirmary, Aberdeen, UK.

Malignant spinal cord compression (MSCC) is a potentially devastating consequence of cancer. Early recognition of the signs and symptoms of MSCC can allow diagnosis prior to the development of irreversible complications. Information provision to patients and doctors regarding the risk of MSCC and a streamlined pathway for further investigation are both key to improving the outcome for patients developing this condition. Read More

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http://dx.doi.org/10.4997/JRCPE.2019.217DOI Listing
June 2019
13 Reads

A Case of Acute Aortoiliac Occlusive Disease Presenting as Cauda Equina Syndrome and Fournier´s Gangrene.

Case Rep Surg 2019 17;2019:4027460. Epub 2019 Apr 17.

Oulu University Hospital, Oulu, Finland.

Aortoiliac occlusive disease presents itself more frequently as chronic claudication, erectile dysfunction, and absent femoral pulses. Its acute manifestation is less frequently encountered in a clinical practice; hence, it presents sometimes as a diagnostic challenge. We illustrate a case of acute aortoiliac occlusive disease presenting with spinal cord ischemia and gluteal and scrotal necroses, which was initially diagnosed and treated as spinal cord compression. Read More

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http://dx.doi.org/10.1155/2019/4027460DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6501124PMC
April 2019
12 Reads

Lower Urinary Tract Symptoms and Urinary Bother Are Common in Patients Undergoing Elective Cervical Spine Surgery.

Clin Orthop Relat Res 2019 04;477(4):872-878

E. G. Lieberman, S. Radoslovich, L. M. Marshall, J. U. Yoo, Department of Orthopaedics and Rehabilitation, Oregon Health & Science University, Portland, OR, USA.

Background: Lower urinary tract symptoms (LUTS) and urinary bother have been reported in adults undergoing surgery and have been associated with urinary tract infections, longer hospital stays, increased surgical costs, and decreased patient satisfaction. Previous reports indicate that up to one in two patients with lumbar spine pathology have moderate-to-severe LUTS, but little is known about LUTS in patients with cervical spine conditions.

Questions/purposes: (1) What is the prevalence of moderate-to-severe LUTS and clinically relevant urinary bother among patients undergoing elective cervical spine surgery? (2) Does the presence of myelopathy affect frequency of moderate-to-severe LUTS or clinically relevant urinary bother among patients undergoing elective cervical spine surgery? (3) Do MRI findings of spinal cord injury or compression correlate with presence and severity of LUTS?

Methods: We performed a cross-sectional study using clinical data collected from adult patients undergoing elective cervical spine surgery. Read More

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http://dx.doi.org/10.1097/CORR.0000000000000666DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6437367PMC
April 2019
9 Reads

Intradural Extramedullary Spinal Neoplasms: Radiologic-Pathologic Correlation.

Radiographics 2019 Mar-Apr;39(2):468-490

From the Department of Neuroradiology, American Institute for Radiologic Pathology, 1011 Wayne Ave, Suite 320, Silver Spring, MD 20910 (K.K.K., R.Y.S.); Department of Radiology, Mayo Clinic, Rochester, Minn (K.K.K.); Uniformed Services University of the Health Sciences, Bethesda, Md (R.Y.S.); and Department of Radiology, Walter Reed National Military Medical Center, Bethesda, Md (R.Y.S.).

While intradural extramedullary spinal disease varies widely, identification of tumors in this location and their radiologic manifestations greatly facilitates narrowing of the diagnostic considerations. Meningioma and schwannoma are the two most common intradural extramedullary tumors, and both are associated with neurofibromatosis. Meningiomas are most common in the thoracic spine and show a strong female predilection and a clinical manifestation related to compression of the spinal cord or nerve roots. Read More

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http://dx.doi.org/10.1148/rg.2019180200DOI Listing
March 2020
18 Reads

Surgical Intervention for Osteoporotic Vertebral Burst Fractures in Middle-low Lumbar Spine with Special Reference to Postoperative Complications Affecting Surgical Outcomes.

Neurol Med Chir (Tokyo) 2019 Mar 13;59(3):98-105. Epub 2019 Feb 13.

Department of Orthopaedic Surgery, Yokohama City University Hospital.

The purpose of this study was to investigate the clinical and radiological features of osteoporotic burst fractures affecting levels below the second lumbar (middle-low lumbar) vertebrae, and to clarify the appropriate surgical procedure to avoid postoperative complications. Thirty-eight consecutive patients (nine male, 29 female; mean age: 74.8 years; range: 60-86 years) with burst fractures affecting the middle-low lumbar vertebrae who underwent posterior-instrumented fusion were included. Read More

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http://dx.doi.org/10.2176/nmc.oa.2018-0232DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6434421PMC
March 2019
7 Reads

Symptomatic Idiopathic Spinal Epidural Lipomatosis in 9 Patients: Clinical, Radiologic, and Pathogenetic Features.

World Neurosurg 2019 Jun 29;126:e33-e40. Epub 2019 Jan 29.

The Atkinson Morley Neurosurgical Department, St. George's Hospital, Tooting, England.

Background: Symptomatic spinal epidural lipomatosis (SSEL) is characterized by hypertrophy of adipose tissue within the spinal canal and consequent neural compromise. The exact pathogenesis remains enigmatic. The authors describe a retrospective case series, define the full clinical spectrum, and discuss possible pathogenetic mechanisms. Read More

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http://dx.doi.org/10.1016/j.wneu.2019.01.098DOI Listing
June 2019
7 Reads

Vertebral solitary bone plasmacytoma in a young adult with Trisomy 21: A case report.

J Spinal Cord Med 2018 Dec 17:1-4. Epub 2018 Dec 17.

a Neurology's Department , Habib Bourguiba Hospital , Sfax , Tunisia.

Context: Solitary bone plasmacytoma (SBP) are rare lesions, accounting for less than 5% of all plasma cell proliferations. We describe a case of a 21-year-old female with Trisomy 21 presenting with cauda equina compression from an SBP.

Findings: Solitary bone plasmacytoma (SBP) is a rare primary bone tumor. Read More

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https://www.tandfonline.com/doi/full/10.1080/10790268.2018.1
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http://dx.doi.org/10.1080/10790268.2018.1557866DOI Listing
December 2018
15 Reads

Anti-coagulation Drug Warfarin Contributes to Severe Adverse Outcomes in Prolonged Unsupervised Use: A Double-edged Sword.

Cureus 2018 Sep 22;10(9):e3347. Epub 2018 Sep 22.

Neurological Surgery, Haider Spine Center, Riverside, USA.

Anti-coagulation medications are widely used in clinical practice, especially in the United States as cardiac-related emergencies are on the rise. An overarching caveat in using anti-coagulation drugs as a long-term treatment regimen, such as warfarin, is that patients are closely monitored by their primary care provider. Routine monthly laboratory examinations are strictly required to assess the international normalized ratio (INR) which measures prothrombin time (PT), providing insight into how long it takes for blood to clot. Read More

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https://www.cureus.com/articles/14892-anti-coagulation-drug-
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http://dx.doi.org/10.7759/cureus.3347DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6248782PMC
September 2018
43 Reads

Pyogenic Spondylodiscitis: Risk Factors for Adverse Clinical Outcome in Routine Clinical Practice.

Med Sci (Basel) 2018 Oct 30;6(4). Epub 2018 Oct 30.

Department of Infection and Tropical Medicine, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

We aimed to describe the clinical features and outcomes of pyogenic spondylodiscitis and to identify factors associated with an unfavourable clinical outcome (defined as death, permanent disability, spinal instability or persistent pain). In our tertiary centre, 91 cases were identified prospectively and a retrospective descriptive analysis of clinical records was performed prior to binary regression analysis of factors associated with an unfavourable outcome. A median 26 days elapsed from the onset of symptoms to diagnosis and 51% of patients had neurological impairment at presentation. Read More

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http://www.mdpi.com/2076-3271/6/4/96
Publisher Site
http://dx.doi.org/10.3390/medsci6040096DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6313505PMC
October 2018
36 Reads

Spontaneous Epidural Hematoma of Cervical Spine.

Int J Spine Surg 2018 Jan 30;12(1):26-29. Epub 2018 Mar 30.

Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Spontaneous cervical epidural hematoma is an uncommon cause of acute spinal cord compression. This is a rare idiopathic condition that leads to acute onset of neurologic deficits, which if not recognized early can have catastrophic consequences. Acute cervical epidural hematoma is definitely a condition of neurologic emergency. Read More

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http://dx.doi.org/10.14444/5005DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162037PMC
January 2018
25 Reads

Fungal cauda equina lesion with delayed cord compression and treatment response.

Clin Neurol Neurosurg 2018 11 21;174:185-186. Epub 2018 Sep 21.

University of Vermont Medical Center, Department of Neurological Sciences, 111 Colchester Avenue, Burlington, VT, 05401, United States. Electronic address:

This is a 24 year old man with profound chronic hydrocephalus found to have a cauda equina abscess composed of Candida albicans. Prior literature reveals a paucity of central nervous system candidiasis. In these previously reported cases, there was evidence of local invasion of surrounding structures; however, this case is a sentinel report of a fungal abscess without evidence of local structural invasion. Read More

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https://linkinghub.elsevier.com/retrieve/pii/S03038467183039
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http://dx.doi.org/10.1016/j.clineuro.2018.09.029DOI Listing
November 2018
50 Reads

Aspiration of sterile post-operative spinal fluid collections using low-dose computed tomography guidance.

J Clin Neurosci 2018 Nov 25;57:202-207. Epub 2018 Aug 25.

Department of Radiologic Sciences, David Geffen School of Medicine, University of California, Los Angeles, Los Angeles, CA 90095, USA. Electronic address:

Sterile postoperative seromas can develop after posterior spinal surgery and cause pain, weakness, and numbness. Management typically involves operative evacuation. We propose that these collections can be managed with percutaneous computed tomography (CT) guided aspiration, potentially saving the patient an additional surgery. Read More

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http://dx.doi.org/10.1016/j.jocn.2018.08.011DOI Listing
November 2018
12 Reads

Symptomatic spinal epidural lipomatosis after combined hormonal and steroidal palliative therapy of prostate cancer.

Spinal Cord Ser Cases 2018 10;4:75. Epub 2018 Aug 10.

3Radiology Department, Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Derby Road, Nottingham, NG7 2UH UK.

Introduction: Spinal epidural lipomatosis (SLE) is an abnormal accumulation of unencapsulated fat. The association of chronic steroid therapy is described as well as obesity and Cushing's syndrome. SLE has a range of neurological presentations such as back pain, myelopathy, and cauda equina syndrome. Read More

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http://dx.doi.org/10.1038/s41394-018-0107-2DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6086905PMC
August 2018
37 Reads

Myelopathy from Intradural Extramedullary Metastasis as an Initial Presentation of Metastatic Melanoma.

Cureus 2018 May 22;10(5):e2668. Epub 2018 May 22.

Neurosurgery, Maimonides Medical Center.

The incidence of metastatic melanoma (MM) has been steadily rising, and it is the third most common metastatic lesion to the central nervous system (CNS). Spinal intradural extramedullary (IDEM) MM is rare, and it is associated with coexisting or antecedent brain metastasis. Metastatic disease to the CNS is a complication of advanced disease, and it generally occurs months to years after initial diagnosis and treatment. Read More

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http://dx.doi.org/10.7759/cureus.2668DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6054369PMC
May 2018
12 Reads

Rapid Fire: Central Nervous System Emergencies.

Emerg Med Clin North Am 2018 Aug 12;36(3):537-548. Epub 2018 Jun 12.

Department of Emergency Medicine, University of Maryland Medical Center, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA; Department of Internal Medicine, University of Maryland Medical Center, 110 South Paca Street, 6th Floor, Suite 200, Baltimore, MD 21201, USA.

Neurologic complications are unfortunately common in oncology patients, with many presenting to the emergency department for diagnosis and management. This case-based review provides a brief overview of the key points in pathophysiology, diagnosis, and management of 2 oncologic central nervous system emergencies: malignant spinal cord compression and intracranial mass. Read More

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http://dx.doi.org/10.1016/j.emc.2018.04.010DOI Listing
August 2018
29 Reads

Incomplete Cord Syndromes: Clinical and Imaging Review.

Radiographics 2018 Jul-Aug;38(4):1201-1222

From the Department of Radiology, SUNY Downstate Medical Center, University Hospital of Brooklyn, 450 Clarkson Ave, Brooklyn, NY 11203 (V.K.K., V.V., Z.A.C., D.L.R.); Department of Radiology, University of California Davis Health System, Sacramento, Calif (M.B.); and Department of Radiology, University of Iowa Hospital and Clinics, Iowa City, Iowa (W.R.K.S.).

The ability to localize the three spinal tracts (corticospinal tract, spinothalamic tract, and dorsal [posterior] columns) involved in incomplete spinal cord syndromes at cross-sectional imaging and knowledge of the classic clinical manifestations of the various syndromes enable optimized imaging evaluation and provide clinicians with information that aids in diagnosis and treatment. The requisite knowledge for localizing these tracts is outlined. The authors review the spinal cord anatomy, blood supply, and course of these tracts and describe the various associated syndromes: specifically, dorsal cord, ventral cord, central cord, Brown-Séquard, conus medullaris, and cauda equina syndromes. Read More

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http://dx.doi.org/10.1148/rg.2018170178DOI Listing
October 2018
41 Reads

Metastatic biphasic pleural mesothelioma presenting with cauda equina syndrome.

Radiol Case Rep 2018 Jun 18;13(3):736-739. Epub 2018 May 18.

Darent Valley Hospital, Kent, UK.

Patient with previous asbestos exposure on a watchful wait and watch regime presents acutely with cauda equina syndrome. Radiological imaging confirmed a mass with direct invasion of the spinal cord. Histology confirmed metastatic pleural mesothelioma. Read More

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http://dx.doi.org/10.1016/j.radcr.2018.03.013DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6026097PMC
June 2018
12 Reads

An unusual cause of combined cauda equina and conus medullaris syndrome.

Neurol India 2018 May-Jun;66(3):886-888

Department of Spine Surgery, VPS Lakeshore Hospital, Ernakulam, Kerala, India.

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http://dx.doi.org/10.4103/0028-3886.232280DOI Listing
September 2019
2 Reads

Kinetic and kinematic variables affecting trunk flexion during level walking in patients with lumbar spinal stenosis.

PLoS One 2018 10;13(5):e0197228. Epub 2018 May 10.

Department of Medical Research and Management for Musculoskeletal Pain, 22nd Century Medical and Research Center, The University of Tokyo, Tokyo, Japan.

Lumbar spinal stenosis causes cauda equina and nerve root compression, resulting in neurological symptoms. Although trunk flexion during level walking may alleviate these symptoms by enabling spinal canal decompression, some patients do not use this strategy. We aimed to identify the kinetic and kinematic variables that affect trunk flexion in patients during level walking. Read More

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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0197228PLOS
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5944950PMC
July 2018
12 Reads

Long-Term Outcomes After Stereotactic Radiosurgery for Spine Metastases: Radiation Dose-Response for Late Toxicity.

Int J Radiat Oncol Biol Phys 2018 07 6;101(3):602-609. Epub 2018 Mar 6.

Department of Radiation Oncology, University of Pittsburgh Medical Center Hillman Cancer Center, Pittsburgh, Pennsylvania. Electronic address:

Purpose: To document the 5- and 10-year rates of late toxicity and vertebral compression fracture (VCF) in long-term survivors after stereotactic radiosurgery for spine metastases.

Methods And Materials: A retrospective review was performed on 562 patients treated with SRS for spine metastases between April 2001 and July 2011. Selecting those with at least 5-year survival after SRS, included were 43 patients who collectively underwent 84 treatments at 54 spine sites. Read More

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http://dx.doi.org/10.1016/j.ijrobp.2018.02.035DOI Listing
July 2018
29 Reads

Disorders of the Cauda Equina.

Authors:
Brent P Goodman

Continuum (Minneap Minn) 2018 04;24(2, Spinal Cord Disorders):584-602

Purpose Of Review: Conditions that affect the cauda equina are a diverse group of disorders that require timely recognition and management. This article reviews cauda equina anatomy, the diagnostic approach to disorders of the cauda equina, features of cauda equina syndrome, and diskogenic and nondiskogenic disorders of the cauda equina.

Recent Findings: Establishing clinical criteria for cauda equina syndrome has been a focus of a number of reviews, although the clinician must maintain a low threshold for emergent imaging in cases of suspected cauda equina syndrome because of the suboptimal reliability of various signs and symptoms in identifying this condition clinically. Read More

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http://dx.doi.org/10.1212/CON.0000000000000584DOI Listing
April 2018
14 Reads

UPPER LUMBAR DISC PROLAPSE.

J West Afr Coll Surg 2018 Apr-Jun;8(2):113-122

Department of Neurological Surgery, University College Hospital Ibadan, Nigeria.

Upper lumbar disc prolapse (ULDP) is a rare and a unique clinical entity which has a potentially devastating clinical outcome. It may manifest with low back or anterior thigh pain, polyradiculopathies (from spinal cord or cauda equina compression) and/or degenerative kyphoscoliosis. Its diagnosis is often difficult and may be missed because of the lack of specific root signs. Read More

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7276217PMC

Caudal lumbar spinal cysts in two French Bulldogs.

Acta Vet Scand 2018 Mar 1;60(1):14. Epub 2018 Mar 1.

Department of Clinical Sciences of Companion Animals, Faculty of Veterinary Medicine, Utrecht University, Yalelaan 108, 3584 CM, Utrecht, The Netherlands.

Background: Spinal cysts are rare findings in veterinary medicine, but they are increasingly recognized due to the availability of advanced imaging techniques. Extradural meningeal cysts in French Bulldogs have not been reported previously and arachnoid cysts (diverticula) have not been reported at the caudal lumbar (L6-L7) region in dogs.

Case Presentation: Two French Bulldogs, aged 5 and 8 years, were referred for evaluation of lower back pain and bilateral hind limb neurological deficits. Read More

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http://dx.doi.org/10.1186/s13028-018-0368-6DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5831591PMC
March 2018
38 Reads

The importance of the bulbocavernosus reflex.

Spinal Cord Ser Cases 2018 10;4. Epub 2018 Jan 10.

Spinal Unit, Centre Calve, Fondation Hopale, Berck-sur-Mer, France.

The BCR consists of the contraction of the bulbocavernosus muscle in response to squeezing the glans penis or clitoris, and is mediated through the pudendal nerve. In case of a complete lesion, the presence of BCR is indicative of intact S2-S4 spinal reflex arcs and loss of supraspinal inhibition, determining an upper motor neuron (UMN) lesion, its absence a lower motor neuron (LMN) lesion. The BCR further helps distinguish conus medullaris from cauda equina syndromes. Read More

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http://dx.doi.org/10.1038/s41394-017-0012-0DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5798690PMC
January 2018
7 Reads

Analysis of stress application at the thoracolumbar junction and influence of vertebral body collapse on the spinal cord and cauda equina.

Exp Ther Med 2018 Feb 27;15(2):1177-1184. Epub 2017 Nov 27.

Department of Orthopedic Surgery, Yamaguchi University Graduate School of Medicine, Ube, Yamaguchi 755-8505, Japan.

The thoracolumbar junction comprises the spinal cord, nerve roots and the cauda equina, exhibiting unique anatomical features that may give rise to a diverse array of symptoms under conditions of injury, thus complicating the diagnosis of compressive disorders. The present study aimed to examine varying degrees and forms of compression at this level of the spinal cord using a two-dimensional model to calculate the relationship of these variables to injury. The degree of compression was expressed as a percentage of the spinal canal that was occupied. Read More

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http://dx.doi.org/10.3892/etm.2017.5570DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC5774549PMC
February 2018
13 Reads

Cauda Equina Syndrome Due to Lumbar Disc Herniation: a Review of Literature.

Folia Med (Plovdiv) 2017 Dec;59(4):377-386

3Department of Medical Imaging, Allergology and Physical Medicine, Faculty of Dental Medicine, Medical University of Plovdiv, Plovdiv, Bulgaria.

Cauda equina syndrome (CES) is a rare neurologic condition that is caused by compression of the cauda equina. Cauda equina consists of spinal nerves L2-L5, S1-S5 and the coccygeal nerve. The compression of these nerve roots can be caused mainly by lumbar disc herniation (45% of all causes). Read More

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http://dx.doi.org/10.1515/folmed-2017-0038DOI Listing
December 2017
28 Reads