9,325 results match your criteria Cauda Equina Syndrome


Traitement chirurgical de la hernie discale lombaire. Hors urgence, 6 semaines après un traitement médical bien conduit et inefficace.

Rev Prat 2016 Apr;66(4):393-396

Service de chirurgie orthopédique et traumatologie, chirurgie du rachis, groupe hospitalier Paris Saint-Joseph, Paris, France.

Surgical treatment of lumbar disc herniations. The definitive treatment of lumbar disc herniation with radiculopathy includes interventional spine procedures and surgical treatment (open or micro discectomy). It is indicated in emergency in specific situations: in case of cauda equina syndrome, motor deficit lower or equal to 3/5 or hyperalgic radicular pain resistant to maximal medical therapy, including opioid drugs. Read More

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Low entropy maps as patterns of the pathological alteration specificity of brain regions: A meta-analysis dataset.

Data Brief 2018 Dec 30;21:1483-1495. Epub 2018 Oct 30.

GCS-FMRI, Koelliker Hospital and Department of Psychology, University of Turin, Turin, Italy.

The data presented in this article are related to the research article entitled "The alteration landscape of the cerebral cortex" (Cauda et al., 2018). Here, we applied a metric called alteration negentropy (A-negentropy) on a large human neuroimaging dataset, in order to denote the "low structural alteration variety" of the altered brain areas. Read More

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December 2018

Seasonal expressions of luteinising hormone receptor, follicle-stimulating hormone receptor and prolactin receptor in the epididymis of the male wild ground squirrel (Spermophilus dauricus).

Reprod Fertil Dev 2018 Dec 4. Epub 2018 Dec 4.

Luteinising hormone (LH), follicle-stimulating hormone (FSH) and prolactin (PRL) are pituitary-derived hormones and mediate their functions through LH receptor (LHR), FSH receptor (FSHR) and PRL receptor (PRLR) respectively. This study aimed to investigate the seasonal expression patterns of LHR, FSHR and PRLR in the epididymis of the male wild ground squirrel during the breeding and non-breeding seasons. Histologically, principal cells, basal cells, cilia and mature spermatozoa were found in the lumen of caput, corpus and cauda epididymidis in the breeding season, whereas in the non-breeding season, cilia and basal cells were rarely found and the epididymidal duct was devoid of spermatozoa. Read More

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December 2018

Structures of filum terminale and characteristics of ependymal cells of its central canal in rats.

Brain Res 2018 Nov 27. Epub 2018 Nov 27.

Central Biomedical Laboratory, Aino University School of Health Science, 4-5-11 Higashiohda, Ibaraki City, Osaka 567-0012, Japan. Electronic address:

The filum terminale (FT) is a potential source of ependymal cells for transplantation. The present study was performed to clarify the characteristics of ependymal cells of the central canal (CC) of the FT in rats. The FT was a thin strand continuous with the conus medullaris (CM), a caudal end of the main spinal cord, situated at the L3-4 level in adult rats. Read More

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November 2018
2 Reads

Persistence of piperacillin concentrations after treatment discontinuation: in cauda venenum?

Intensive Care Med 2018 Nov 27. Epub 2018 Nov 27.

Department of Laboratory Medicine, Ghent University Hospital, Ghent, Belgium.

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November 2018

A mobile hemangioblastoma of the cauda equina: Case report and review of the literature.

J Spinal Cord Med 2018 Nov 26:1-4. Epub 2018 Nov 26.

a Department of Neurosurgery , The Second Affiliated Hospital of Nanchang University , Nanchang , People's Republic of China.

Context: Cases of migratory spinal tumors have been reported since 1963. Most involve spinal schwannomas, which are benign tumors of the lining of nerve cells. We report a rare case of a mobile spinal hemangioblastoma, which is a type of benign vascular tumor. Read More

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November 2018

Factors that influence neurological deficit and recovery in lumbar disc prolapse-a narrative review.

Int Orthop 2018 Nov 24. Epub 2018 Nov 24.

Department of spine surgery, Ganga Medical centre & Hospital. Pvt. Ltd, #313, Mettupalayam road, Sai baba Colony, Coimbatore, Tamilnadu, 641001, India.

Neurodeficit due to lumbar disc herniation (LDH) is a serious complication and can range from sensory hypoesthesia in a single dermatome to a debilitating condition like cauda equina syndrome (CES). Many authors have described variable clinical and radiological risk factors for neurodeficit in LDH. Similarly the prognostic factors influencing recovery have been variable across the studies. Read More

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November 2018
8 Reads

Anti-coagulation Drug Warfarin Contributes to Severe Adverse Outcomes in Prolonged Unsupervised Use: A Double-edged Sword.

Cureus 2018 Sep 22;10(9):e3347. Epub 2018 Sep 22.

Neurological Surgery, Haider Spine Center, Riverside, USA.

Anti-coagulation medications are widely used in clinical practice, especially in the United States as cardiac-related emergencies are on the rise. An overarching caveat in using anti-coagulation drugs as a long-term treatment regimen, such as warfarin, is that patients are closely monitored by their primary care provider. Routine monthly laboratory examinations are strictly required to assess the international normalized ratio (INR) which measures prothrombin time (PT), providing insight into how long it takes for blood to clot. Read More

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September 2018
4 Reads

Does the Surgical Timing and Decompression Alone or Fusion Surgery in Lumbar Stenosis Influence Outcome in Cauda Equina Syndrome?

Asian Spine J 2018 Nov 27. Epub 2018 Nov 27.

Department of Spine Surgery, Stavya Spine Hospital and Research Institute, Ahmedabad, India.

Study Design: A retrospective comparative analysis of 64 patients with cauda equina syndrome (CES), who underwent either decompression alone (NF) or fusion (F) surgery.

Purpose: We compared the outcomes and timing effects.

Overview Of Literature: CES can cause loss of autonomic control of vesicular function and lower limb neurological deficits. Read More

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November 2018
6 Reads

Visualization of the electrical activity of the cauda equina using a magnetospinography system in healthy subjects.

Clin Neurophysiol 2018 Nov 12;130(1):1-11. Epub 2018 Nov 12.

Department of Orthopedic Surgery, Tokyo Medical and Dental University, 1-5-45 Yushima, Bunkyo-ku, Tokyo 113-8510, Japan. Electronic address:

Objective: To establish a method to measure cauda equina action fields (CEAFs) and visualize the electrical activities of the cauda equina in a broadly aged group of healthy adults.

Methods: Using a 124-channel magnetospinography (MSG) system with superconducting interference devices, the CEAFs of 43 healthy volunteers (22-64 years of age) were measured after stimulation of the peroneal nerve at the knee. Reconstructed currents were obtained from the CEAFs and superimposed on the X-ray image. Read More

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November 2018

Secondary sacral tethered cord syndrome after treatment of secondary cervical syringomyelia.

J Clin Neurosci 2018 Nov 20. Epub 2018 Nov 20.

Department of Neurosurgery, HELIOS Klinikum, Erfurt, Germany.

A female patient operated at the age of 11 on a pilocytic astrocytoma in the posterior fossa, was re-operated for a recurrence 9 years later. A Torkildsen drain was placed in the 4th ventricle and she remained asymptomatic for 15 years before presenting again with acute hydrocephalus, tonsillar herniation, and a massive cervicothoracic syrinx. The symptoms retreated following craniocervical untethering and decompression. Read More

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November 2018
1 Read

Evolution of major non-HIV-related comorbidities in HIV-infected patients in the Italian Cohort of Individuals, Naïve for Antiretrovirals (ICONA) Foundation Study cohort in the period 2004-2014.

HIV Med 2018 Nov 21. Epub 2018 Nov 21.

University College London, London, UK.

Objectives: The management of HIV disease is complicated by the incidence of a new spectrum of comorbid noncommunicable diseases (NCDs). It is important to document changes in the prevalence of NCDs over time. The aim of the study was to describe the impact of ageing on HIV markers and on the prevalence of NCDs in people living with HIV (PLWHIV) in the Italian Cohort of Individuals, Naïve for Antiretrovirals (ICONA) seen for care in 2004-2014. Read More

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November 2018
1 Read

Intradural Disc a Diagnostic Dilemma: Case Series and Review of Literature.

Asian J Neurosurg 2018 Oct-Dec;13(4):1033-1036

Department of Orthopedic, King Edward Memorial Hospital, Mumbai, India.

Introduction: We present a case series of six cases of intradural disc herniation at L4-L5 level diagnosed on the basis of intraoperative findings.

Result: All our cases, on preoperative magnetic resonance imaging (MRI) were reported as having diffuse annular bulge with large posterocentral extrusion. Our study comprised patients in age group of 30-60 years. Read More

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November 2018
1 Read

Seminal vesicle secretory protein 7, PATE4, is not required for sperm function but for copulatory plug formation to ensure fecundity.

Biol Reprod 2018 Nov 18. Epub 2018 Nov 18.

Research Institute for Microbial Diseases, Osaka University, Suita, Osaka 5650871, JAPAN.

Seminal vesicle secretions (SVSs), together with spermatozoa, are ejaculated into the female reproductive tract. SVS7, also known as PATE4, is one of the major SVS proteins found in the seminal vesicle, copulatory plug, and uterine fluid after copulation. Here, we generated Pate4 knockout (-/-) mice and examined the detailed function of PATE4 on male fecundity. Read More

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November 2018
2 Reads

A case of neurofibromatosis type 2 (NF2) with classic imaging and skin findings.

Med J Armed Forces India 2018 Oct 5;74(4):407-409. Epub 2017 Oct 5.

Classified Specialist (ENT), Command Hospital (Central Command), Lucknow, India.

Neurofibromatosis is a neurocutaneous, tumor predisposing, inheritable disorder characterized by tumors of the brain and spine and the presence of skin lesions. The most important tumors associated with neurofibromatosis are vestibular nerve schwannomas, with others being meningiomas and ependymomas. The cord is also affected by tumors, ependymoma being the commonest, besides meningiomas and schwannomas. Read More

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October 2018
7 Reads

Guillain-Barré Syndrome and Low Back Pain: Two Cases and Literature Review.

Open Med (Wars) 2018 22;13:503-508. Epub 2018 Oct 22.

Department of Neurology, Brain Research Center, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University, Hangzhou 310016, Hangzhou China.

Purpose: To describe the clinical, electrophysiological, and lumbar magnetic resonance imaging (MRI) features of two cases of atypical Guillain-Barré syndrome (GBS). Methods We reported two GBS variant cases with initial and prominent symptoms of low back pain. We analysed their clinical, electrophysiological, and lumbar MRI features. Read More

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October 2018
6 Reads

Lumbar Intraspinal Osteolipoma Presenting as Cauda Equina Syndrome: A Case Report and Review of Literature.

Case Rep Orthop 2018 22;2018:1945149. Epub 2018 Oct 22.

Department of Spine Surgery, 313 Mettupalayam Road, Ganga Hospital, Coimbatore, India.

Introduction: Osteolipomas are uncommon variants of lipoma. These lesions have been usually reported to arise from the oral cavity, brain, and neck and scarcely from the knee and thigh. Intraspinal osteolipomas are rare. Read More

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October 2018
4 Reads

Post-transplant lymphoproliferative disorder of the cauda equina in a kidney transplant recipient.

Spinal Cord Ser Cases 2018 6;4:100. Epub 2018 Nov 6.

1Department of Orthopedic Surgery, Keio University School of Medicine, Tokyo, Japan.

Introduction: Post-transplant lymphoproliferative disorder (PTLD) is a condition associated with post-transplant immunosuppression that can develop in various organs, including the grafted one. However, it has rarely been reported in nerve tissue. We encountered an unexpected case of PTLD in the cauda equina of a kidney transplant recipient who was being treated with chronic immunosuppressive therapies. Read More

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November 2018
1 Read

Successful treatment of central nervous system myeloma manifesting as cauda equina nodules with intrathecal chemotherapy, lenalidomide and dexamethasone.

BMJ Case Rep 2018 Nov 8;2018. Epub 2018 Nov 8.

Medical Imaging Department, ACT Health, Canberra, Australian Capital Territory, Australia.

We report a case of central nervous system myeloma manifesting as cauda equina nodules, successfully treated with triple intrathecal (IT) chemotherapy, lenalidomide and dexamethasone. After presenting with multiple plasmacytomas which led to a diagnosis of non-secretory myeloma at age 56, the patient underwent multiple episodes of treatment for relapsing myeloma over a 7-year period. In March 2017, he presented with declining gait over a month with bilateral hip flexion weakness, absent lower limb reflexes and dorsal column loss. Read More

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November 2018
3 Reads

Effects of secretome on cisplatin-induced testicular dysfunction in rats.

Vet World 2018 Sep 29;11(9):1349-1356. Epub 2018 Sep 29.

Department of Anatomy, Faculty of Veterinary Medicine, Universitas Gadjah Mada, Yogyakarta, 55821, Indonesia.

Background: Testicular dysfunction is a degenerative disorder characterized by failure in the synthesis of reproductive hormones and spermatogenesis. Secretome derived from the human umbilical mesenchymal stem cell (MSC) has been reported to repair some degenerative disorders.

Aim: This study aimed to investigate the effect of secretome derived from the human umbilical MSCs on cisplatin-induced testicular dysfunction in rats. Read More

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September 2018
2 Reads

Lipopolysaccharide-induced testicular dysfunction and epididymitis in mice: a critical role of tumor necrosis factor alpha.

Biol Reprod 2018 Nov 6. Epub 2018 Nov 6.

Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Peking Union Medical College, Beijing, China.

Systemic inflammation may impair male fertility, and its underlying mechanisms remain poorly understood. The present study investigates the effect of lipopolysaccharide (LPS)-induced systemic inflammation on the testis and epididymis in mice. Intraperitoneal injection of LPS significantly impaired testicular functions, including testosterone production, spermatogenesis, and blood-testis barrier permeability. Read More

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November 2018
5 Reads

A Case Report of Paravertebral Block: A Safe Alternative for Microdiscectomy in a Pregnant Patient.

A A Pract 2018 Nov 1. Epub 2018 Nov 1.

From the Department of Anesthesiology and Pain, Fortis Memorial Research Institute, Gurugram, Haryana, India.

Nonobstetric surgery during pregnancy is common. Administration of safe anesthesia to a pregnant patient, while minimizing its side effects on the fetus, is a major challenge for the anesthesiologist. Both general anesthesia and central neuraxial block are associated with risks during early pregnancy. Read More

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November 2018

Modification of sperm fatty acid composition during epididymal maturation in bats.

Reproduction 2018 Oct 1. Epub 2018 Oct 1.

P Christe, Department of Ecology and Evolution, Universite de Lausanne Departement d'ecologie et evolution, Lausanne, Switzerland.

Biochemical properties of polyunsaturated fatty acids (PUFAs) are fundamental to sperm movements. Amongst all adjustments operated during epididymal maturation, sperm membrane lipid composition is remodelled. Specifically, the proportion of PUFAs usually increases from the caput towards the cauda epididymidis. Read More

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October 2018
5 Reads

[Effect of oral appliance on reproductive system of the male New-Zealand rabbit with obstructive sleep apnea-hypopnea syndrome].

Zhonghua Yi Xue Za Zhi 2018 Oct;98(38):3090-3095

Department of Urology, Children's Hospital of Hebei Province, Shijiazhuang 050031, China.

To observe the effect of the mandible advanced device on the reproductive system of the male New-Zealand rabbit with obstructive sleep apnea-hypopnea syndrome (OSAHS). Thirty male New-Zealand white rabbits were randomly divided into three groups (with 10 rabbits in each group): sleep apnea-hypopnea syndrome group (group OSAHS), mandible advanced device group (group MAD) and control group. On the basis of the OSAHS animal model, mandible advanced devices were used for group MAD animals. Read More

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October 2018
2 Reads

Toxicity and Mutagenicity Evaluation Following RISUG Contraception Reversal in Rats.

Int J Toxicol 2018 Nov 1:1091581818809473. Epub 2018 Nov 1.

1 Department of Zoology, Centre for Advanced Studies, University of Rajasthan, Jaipur, Rajasthan, India.

Reestablishment of fertility, after a male contraceptive method, is of great concern. In this context, RISUG (Reversible Inhibition of Sperm Under Guidance) has been evaluated for its mutagenicity following reversibility with dimethyl sulfoxide (DMSO)/sodium bicarbonate (NaHCO) in Wistar albino rats. Animals were divided into 7 groups, namely, sham-operated control, vas occlusion with RISUG for 90 and 360 days, reversal with DMSO and NaHCO after 90 and 360 days, respectively. Read More

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November 2018
3 Reads

Pyogenic Spondylodiscitis: Risk Factors for Adverse Clinical Outcome in Routine Clinical Practice.

Med Sci (Basel) 2018 Oct 30;6(4). Epub 2018 Oct 30.

Department of Infection and Tropical Medicine, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne NE1 4LP, UK.

We aimed to describe the clinical features and outcomes of pyogenic spondylodiscitis and to identify factors associated with an unfavourable clinical outcome (defined as death, permanent disability, spinal instability or persistent pain). In our tertiary centre, 91 cases were identified prospectively and a retrospective descriptive analysis of clinical records was performed prior to binary regression analysis of factors associated with an unfavourable outcome. A median 26 days elapsed from the onset of symptoms to diagnosis and 51% of patients had neurological impairment at presentation. Read More

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October 2018
3 Reads

Economic Consequences of Investing in Anti-HCV Antiviral Treatment from the Italian NHS Perspective: A Real-World-Based Analysis of PITER Data.

Pharmacoeconomics 2018 Oct 30. Epub 2018 Oct 30.

CEIS-Economic Evaluation and HTA (EEHTA), Faculty of Economics, University of Rome "Tor Vergata", Via Columbia 2, 00133, Rome, Italy.

Objective: We estimated the cost consequence of Italian National Health System (NHS) investment in direct-acting antiviral (DAA) therapy according to hepatitis C virus (HCV) treatment access policies in Italy.

Methods: A multistate, 20-year time horizon Markov model of HCV liver disease progression was developed. Fibrosis stage, age and genotype distributions were derived from the Italian Platform for the Study of Viral Hepatitis Therapies (PITER) cohort. Read More

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October 2018

Accuracy of the kissing sign on lumbar spine MRI in cases of axillary disc herniation and the surgical correlation: an Indian multi-center study.

Rev Bras Ortop 2018 Nov-Dec;53(6):681-686. Epub 2018 Feb 6.

Interventional Radiology, Dr. B. L. Kapur Hospital, New Delhi, India.

Objectives: Magnetic resonance imaging has proven to be a valuable tool in the assessment of disc abnormalities. Two types of disc extrusion can be described according to the direction of herniated disc material: shoulder type and axillary type. Axillary disc herniation is described when the extruded disc fragment lies in the recess between the lateral border of cauda equina and medial to the nerve roots, while in the shoulder type the disc lies lateral to the nerve roots. Read More

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February 2018

Cauda equina syndrome-the questions.

Authors:
Andrew Quaile

Int Orthop 2018 Oct 29. Epub 2018 Oct 29.

Hampshire Clinic, Basing Road, Basingtoke, RG24 7AL, UK.

Cauda equina syndrome is a devastating condition often following an innocent pathology in the form of a disc prolapse. The effect on sufferers, however, can be lifelong. It is necessary to make a diagnosis as expeditiously as possible via adequate history, clinical examination and appropriate imaging to offer treatment, in the form of decompressive surgery within 48 hours. Read More

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October 2018
1 Read

Effects of Estrogen Treatment on Aging in the Rat Epididymis.

Anat Rec (Hoboken) 2018 Oct 26. Epub 2018 Oct 26.

Department of Biomedical Sciences, Grand Valley State University, Allendale, Michigan.

Previous studies from our laboratory demonstrated that estrogen signaling in the testis contributes to maintaining spermatogenesis in adult rats, and that estrogen treatment attenuated the age-associated decline in sperm production. The purpose of this study was to determine if epididymal function is also altered with age, and what effects estrogen treatment may have on the epididymis during aging. We compared untreated rats at 3 and 15 months of age to 18-month-old vehicle-treated and estrogen treated rats. Read More

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October 2018
5 Reads

Brain structural alterations are distributed following functional, anatomic and genetic connectivity.

Brain 2018 Nov;141(11):3211-3232

GCS-fMRI, Koelliker Hospital and Department of Psychology, University of Turin, Turin, Italy.

The pathological brain is characterized by distributed morphological or structural alterations in the grey matter, which tend to follow identifiable network-like patterns. We analysed the patterns formed by these alterations (increased and decreased grey matter values detected with the voxel-based morphometry technique) conducting an extensive transdiagnostic search of voxel-based morphometry studies in a large variety of brain disorders. We devised an innovative method to construct the networks formed by the structurally co-altered brain areas, which can be considered as pathological structural co-alteration patterns, and to compare these patterns with three associated types of connectivity profiles (functional, anatomical, and genetic). Read More

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November 2018

Depression Increases the Rates of Neurological Complications and Failed Back Surgery Syndrome in Patients Undergoing Lumbar Spine Surgery.

Clin Spine Surg 2018 Oct 22. Epub 2018 Oct 22.

Department of Orthopaedic Surgery, Keck School of Medicine, University of Southern California, Los Angeles, CA.

Study Design: This was a retrospective database study.

Objective: The aim of this study was to use a large sample to accurately determine risk factors and rates of neurological complications in patients undergoing commonly performed lumbar spine surgeries.

Summary Of Background Data: Damage to neurological structures and failed back surgery syndrome (FBSS) are among the most feared complications of lumbar spine surgery. Read More

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October 2018
3 Reads

Intravascular large B-cell lymphoma presenting as an isolated cauda equina-conus medullaris syndrome - A case report.

J Spinal Cord Med 2018 Oct 22:1-4. Epub 2018 Oct 22.

b Department of Neurology , University of Missouri School of Medicine , Columbia , Missouri , USA.

Context: Intravascular large B-cell lymphoma (IVLBCL) is a rare form of Non-Hodgkin lymphoma. The central nervous system, skin and hematopoietic system are the most commonly affected sites. We report a case of IVLBCL presenting as a combined conus medullaris-cauda equina syndrome. Read More

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October 2018
5 Reads

Paternal Exercise Improves Glucose Metabolism in Adult Offspring.

Diabetes 2018 Dec 21;67(12):2530-2540. Epub 2018 Oct 21.

Section on Integrative Physiology and Metabolism, Joslin Diabetes Center, Boston, MA

Poor paternal diet has emerged as a risk factor for metabolic disease in offspring, and alterations in sperm may be a major mechanism mediating these detrimental effects of diet. Although exercise in the general population is known to improve health, the effects of paternal exercise on sperm and offspring metabolic health are largely unknown. Here, we studied 7-week-old C57BL/6 male mice fed a chow or high-fat diet and housed either in static cages (sedentary) or cages with attached running wheels (exercise trained). Read More

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December 2018
19 Reads

Reproductive functions in Desmodus rotundus: A comparison between seasons in a morphological context.

PLoS One 2018 17;13(10):e0205023. Epub 2018 Oct 17.

Department of General Biology, Federal University of Viçosa, Viçosa, Minas Gerais, Brazil.

Reproductive seasonality in Neotropical bats has been assessed to the better understand their reproductive behavior. This knowledge is especially important for the control of Desmodus rotundus population as it is a transmitter of rabies virus. Therefore, we aimed to evaluate the functional activity of testis and epididymis of D. Read More

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October 2018

Bladder Recovery Patterns in Patients with Complete Cauda Equina Syndrome: A Single-Center Study.

Asian Spine J 2018 Dec 16;12(6):981-986. Epub 2018 Oct 16.

Department of Spine Surgery, Indian Spinal Injuries Centre, New Delhi, India.

Study Design: Retrospective case series.

Purpose: Cauda equina syndrome (CES) is associated with etiologies such as lumbar disc herniation (LDH) and lumbar canal stenosis (LCS). CES has a prevalence of 2% among patients with LDH and exhibits variable outcomes, even with early surgery. Read More

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December 2018
6 Reads

The Natural Course of Myxopapillary Ependymoma : An Unusual Case Report and Review of The Literature.

World Neurosurg 2018 Oct 12. Epub 2018 Oct 12.

Craniospinal Surgery Center , Ankara, Turkey.

Spinal cord ependymomas are the most frequent primary intramedullary tumours of the cord in middle age (40-60 years of age). Myixopapillary ependymomas are low incidence tumours and occur in the cauda equina and conus medullaris. They are typically described as fleshly, sausage-shaped, vascular lesions. Read More

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October 2018
6 Reads

[Effect of long-term deep slow-wave sleep deprivation on the reproductive system in male rats].

Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi 2018 Aug;36(8):585-589

The institute of Endocrinology, Metabolic Disease Hospital of Tianjin Medical University, Key Laboratory of Hormones and Development, Key Laboratory of Metabolic Disease, Basic Medical college of Tianjin Medical University, Tianjin 300070, China.

To investigate the effect of long-term deep slow-wave sleep deprivation on the gonad axis, sperm abnormality rate, and structure of the testis in male rats and possible mechanisms. A total of 30 specific pathogen-free male Wistar rats aged 5 weeks were randomly divided into slow-wave sleep deprivation group 1 (SD1 group) , slow-wave sleep and sleep time deprivation group 2 (SD2 group) , and control group, with 10 rats in each group. The flower pot method was used to establish a model of sleep deprivation. Read More

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August 2018
4 Reads

Cauda equina: Normal anatomy.

J Med Imaging Radiat Oncol 2018 Oct;62 Suppl 1:123

Department of Radiology, Concord Repatriation General Hospital, Concord, New South Wales, Australia.

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October 2018
1 Read

The clinical features and outcome of scan-negative and scan-positive cases in suspected cauda equina syndrome: a retrospective study of 276 patients.

J Neurol 2018 Dec 8;265(12):2916-2926. Epub 2018 Oct 8.

Centre for Clinical Brain Sciences, University of Edinburgh, Edinburgh, UK.

Background: The majority of patients presenting with suspected clinical cauda equina syndrome (CES) have no identifiable structural cause for their symptoms ('scan-negative' CES). Understanding these patients aids clinical differentiation and management in CES.

Methods: A retrospective electronic note review was undertaken of patients presenting with suspected CES, defined as ≥ 1 of acute bladder, bowel, sexual dysfunction or saddle numbness, to a regional neurosciences centre. Read More

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December 2018
2 Reads

Probing the Origins of 1,800 MHz Radio Frequency Electromagnetic Radiation Induced Damage in Mouse Immortalized Germ Cells and Spermatozoa .

Front Public Health 2018 21;6:270. Epub 2018 Sep 21.

Priority Research Centre for Reproductive Biology, School of Environmental and Life Sciences, Discipline of Biological Sciences, University of Newcastle, Callaghan, NSW, Australia.

As the use of mobile phone devices is now highly prevalent, many studies have sought to evaluate the effects of the radiofrequency-electromagnetic radiation (RF-EMR) on both human health and biology. While several such studies have shown RF-EMR is capable of inducing cellular stress, the physicobiological origin of this stress remains largely unresolved. To explore the effect of RF-EMR on the male reproductive system, we exposed cultured mouse spermatogonial GC1 and spermatocyte GC2 cell lines, as well as cauda epididymal spermatozoa to a waveguide generating continuous wave RF-EMR (1. Read More

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September 2018
1 Read

Spinal Emergencies in Primary Care Practice.

Am J Med 2018 Oct 3. Epub 2018 Oct 3.

Division of Spine Surgery, Department of Orthopaedic Surgery, Warren Alpert Medical School, Brown University, Providence, RI.

Atraumatic spinal emergencies often present a diagnostic and management dilemma for health care practitioners. Spinal epidural abscess, cauda equina syndrome, and spinal epidural hematoma are conditions that can insidiously present to outpatient medical offices, urgent care centers, and emergency departments. Unless a high level of clinical suspicion is maintained, these clinical entities may be initially misdiagnosed and mismanaged. Read More

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October 2018
4 Reads

Spontaneous Epidural Hematoma of Cervical Spine.

Int J Spine Surg 2018 Jan 30;12(1):26-29. Epub 2018 Mar 30.

Department of Neurosurgery, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.

Spontaneous cervical epidural hematoma is an uncommon cause of acute spinal cord compression. This is a rare idiopathic condition that leads to acute onset of neurologic deficits, which if not recognized early can have catastrophic consequences. Acute cervical epidural hematoma is definitely a condition of neurologic emergency. Read More

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January 2018
1 Read

Effect of chrysin on methotrexate-induced testicular damage in rats.

Andrologia 2018 Oct 1:e13145. Epub 2018 Oct 1.

Department of Pathology, Veterinary Faculty, Yuzuncu Yıl University, Van, Turkey.

This study was conducted on 28 male Wistar albino rats to determine the effects of chrysin on methotrexate-induced damage to testicular tissue. Rats were grouped into four groups of seven rats reach: Group 1 (n = 7) was the control group to which no drugs were administered; this group was only provided with food and water. Group 2 (n = 7) was administered 20 mg/kg of methotrexate once intraperitoneally. Read More

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October 2018

Fungal cauda equina lesion with delayed cord compression and treatment response.

Clin Neurol Neurosurg 2018 Nov 21;174:185-186. Epub 2018 Sep 21.

University of Vermont Medical Center, Department of Neurological Sciences, 111 Colchester Avenue, Burlington, VT, 05401, United States. Electronic address:

This is a 24 year old man with profound chronic hydrocephalus found to have a cauda equina abscess composed of Candida albicans. Prior literature reveals a paucity of central nervous system candidiasis. In these previously reported cases, there was evidence of local invasion of surrounding structures; however, this case is a sentinel report of a fungal abscess without evidence of local structural invasion. Read More

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November 2018
10 Reads

Informed appropriate imaging for low back pain management: A narrative review.

J Orthop Translat 2018 Oct 27;15:21-34. Epub 2018 Aug 27.

Department of Radiology, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, Brazil.

Most patients with acute low back pain (LBP), with or without radiculopathy, have substantial improvements in pain and function in the first 4 weeks, and they do not require routine imaging. Imaging is considered in those patients who have had up to 6 weeks of medical management and physical therapy that resulted in little or no improvement in their LBP. It is also considered for those patients presenting with suspicion for serious underlying conditions, such as cauda equina syndrome, malignancy, fracture and infection. Read More

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October 2018
7 Reads

The proteome of pig spermatozoa is remodeled during ejaculation.

Mol Cell Proteomics 2018 Sep 26. Epub 2018 Sep 26.

Murcia University, Spain

Proteins are essential for sperm function, including their fertilizing capacity. Pig spermatozoa, emitted in well-defined ejaculate fractions, vary in their functionality, which could be related to different sperm protein composition. This study aimed (i) to update the porcine sperm proteome and (ii) to identify proteins differentially expressed in mature spermatozoa from cauda epididymis and those delivered in separate ejaculate fractions. Read More

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September 2018
1 Read

Effect of Extender and Freezing Rate on Quality Parameters and In Vitro Fertilization Capacity of Alpaca Spermatozoa Recovered from Cauda Epididymis.

Biopreserv Biobank 2018 Sep 26. Epub 2018 Sep 26.

1 Department of Animal Production, Faculty of Animal Husbandry, National Agrarian University La Molina , Lima, Peru .

In alpacas, improvement of reproductive efficiency of male camelids is limited by the small testicular size, low spermatozoa production, and low quality of semen. In this study we aim to evaluate the effect of two extenders and two freezing rates on post-thaw quality of sperm recovered from alpaca epididymis with two methods (flushing and mincing), and to evaluate the in vitro fertilization (IVF) capacity of frozen sperm selected with two different selection methods (washing and swim-up). Sperm samples were processed with Tris-egg yolk or Bioxcell extenders and frozen with slow freezing and fast freezing. Read More

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September 2018

Mechanical Low Back Pain.

Am Fam Physician 2018 Oct;98(7):421-428

Martin Army Community Hospital, Fort Benning, GA, USA.

Low back pain is usually nonspecific or mechanical. Mechanical low back pain arises intrinsically from the spine, intervertebral disks, or surrounding soft tissues. Clinical clues, or red flags, may help identify cases of nonmechanical low back pain and prompt further evaluation or imaging. Read More

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October 2018
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