799 results match your criteria Catheterization Umbilical Artery


Risk factors for umbilical vascular catheter-related adverse events: A scoping review.

Aust Crit Care 2021 Jun 1. Epub 2021 Jun 1.

Clinical and Health Sciences, University of South Australia, PO Box 2471, South Australia, 5000, Australia. Electronic address:

Introduction: Adverse events associated with umbilical catheters include malposition, bloodstream infections, thrombosis, tip migration, and extravasation, resulting in loss of vascular access and increased risk of morbidity and mortality. There is a need for greater understanding of risk factors associated with adverse events to inform safe practice.

Objectives: The aim of the study was to summarise the existing evidence regarding risk factors for umbilical catheter-related adverse events to inform the undertaking of future research. Read More

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Off label use of PICC as umbilical arterial catheter: Clinical case series.

J Vasc Access 2021 Apr 7:11297298211008089. Epub 2021 Apr 7.

Neonatal Intensive Care Unit, Ospedale Infermi, AUSL Romagna, Rimini, Italy.

Umbilical arterial catheters are often placed at birth in critical ill neonates. Advantages of umbilical arterial catheterization include continuous blood pressure monitoring, accurate blood gas and frequent blood samplings. We described the off-label use of a third generation polyurethane power injectable 3 Fr single lumen peripheral inserted central catheter as umbilical arterial catheter. Read More

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Incidence and risk factors of subclinical umbilical catheter-related thrombosis in neonates.

Thromb Res 2020 10 25;194:21-25. Epub 2020 May 25.

Department of Radiology, Haeundae Paik Hospital, Inje University College of Medicine, Pusan, Republic of Korea.

Introduction: This study aimed to determine the risk factors for subclinical umbilical catheter-related thrombosis (UCRT) and its association with clinical morbidities.

Materials And Methods: In infants without any symptoms associated with umbilical catheterization, the presence of thrombosis was monitored using abdominal ultrasonography within 1 week after umbilical catheter removal. The association between UCRT and the clinical variables was analyzed by comparing the groups with and without UCRT. Read More

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October 2020

Neonatal aortic thrombosis: A life threatening complication of umbilical artery catheterisation.

Med J Malaysia 2020 03;75(2):173-174

Universiti Putra Malaysia, Faculty of Medicine and Health Sciences, Department of Paediatric, Serdang, Malaysia.

Umbilical artery catheterisation is considered the standard of care for arterial access in neonatal intensive care unit. It is routinely used for blood sampling and blood pressure monitoring. Unfortunately, an indwelling umbilical catheter have been associated with thrombotic complication which may result in either partial or complete occlusion of the aorta. Read More

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In-vivo vascular application via ultra-fast bioprinting for future 5D personalised nanomedicine.

Sci Rep 2020 02 21;10(1):3205. Epub 2020 Feb 21.

Department of Medicine and Surgery, University of Parma, via Gramsci 14, 43126, Parma, IT, Italy.

The design of 3D complex structures enables new correlation studies between the engineering parameters and the biological activity. Moreover, additive manufacturing technology could revolutionise the personalised medical pre-operative management due to its possibility to interplay with computer tomography. Here we present a method based on rapid freeze prototyping (RFP) 3D printer, reconstruction cutting, nano dry formulation, fast freeze gelation, disinfection and partial processes for the 5D digital models functionalisation. Read More

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February 2020

Umbilical artery catheter, aortic dissection, carotid cannulation, and pseudoaneurysm in a neonate: A tale of propagating pathology.

Ann Pediatr Cardiol 2020 Jan-Mar;13(1):87-90. Epub 2019 Jul 19.

Department of Pediatric Intensive Care, Royal Brompton Hospital, London, United Kingdom.

Arterial dissections are uncommon in neonates. Complications include thrombosis, bleeding, dissection, aneurysm and pseudoaneurysm. We report an unusual case of multisite pathology (dissection and pseudoaneurysm) following common vascular interventions. Read More

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A Novel Epigenetic Drug-Eluting Balloon Angioplasty Device: Evaluation in a Large Animal Model of Neointimal Hyperplasia.

Cardiovasc Drugs Ther 2019 12;33(6):687-692

Eastern Health Clinical School, Monash University, Clayton, Australia.

Purpose: Drug-eluting balloon catheters (DEBc) coated with paclitaxel (PTX) have been associated with potential safety concerns. An efficacious but less toxic balloon coating may reduce these outcomes. We evaluated a novel DEBc, Epi-Solve, coated with metacept-3 (MCT-3), a member of the histone deacetylase inhibitor (HDACi) class of epigenetic agents, in a large animal model of neointimal hyperplasia (NIH). Read More

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December 2019

Hepatocyte Transplantation to the Liver via the Splenic Artery in a Juvenile Large Animal Model.

Cell Transplant 2019 Dec 17;28(1_suppl):14S-24S. Epub 2019 Dec 17.

Department of Surgery, Campus Charité Mitte | Campus Virchow-Klinikum, Experimental Surgery, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin, Humboldt-Universität zu Berlin, and Berlin Institute of Health, Berlin, Germany.

Hepatocyte transplantation (HcTx) is a promising approach for the treatment of metabolic diseases in newborns and children. The most common application route is the portal vein, which is difficult to access in the newborn. Transfemoral access to the splenic artery for HcTx has been evaluated in adults, with trials suggesting hepatocyte translocation from the spleen to the liver with a reduced risk for thromboembolic complications. Read More

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December 2019

Abdominal aortic perforation by an umbilical arterial catheter.

Arch Dis Child Fetal Neonatal Ed 2020 Jan 29;105(1):40. Epub 2019 Aug 29.

Neonatology, Rambam Health Care Campus, Haifa, Israel.

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January 2020

Umbilical catheters as vectors for generalized bacterial infection in premature infants regardless of antibiotic use.

J Med Microbiol 2019 Sep 5;68(9):1306-1313. Epub 2019 Jul 5.

Neonatal Intensive Care Unit, Department of Pediatrics, Jagiellonian University Medical College, Kraków, Poland.

Umbilical catheterization offers unique vascular access that is only possible in the neonatal setting due to unobstructed umbilical vessels from foetal circulation. With the cut of the umbilical cord, two arteries and a vein are dissected, allowing quick and painless catheterization of the neonate. Unfortunately, keeping the umbilical access sterile is challenging due to its mobility and necrosis of the umbilical stump, which makes it a perfect model for vessel catheter colonization analysis. Read More

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September 2019

Burden of hypoxia and intraventricular haemorrhage in extremely preterm infants.

Arch Dis Child Fetal Neonatal Ed 2020 May 29;105(3):242-247. Epub 2019 Jun 29.

Neonatal Unit, Rosie Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.

Objective: Thresholds of cerebral hypoxia through monitoring of near-infrared spectroscopy tissue oxygenation index (TOI) were used to investigate the relationship between intraventricular haemorrhage (IVH) and indices of hypoxia.

Design: Prospective observational study.

Setting: A single-centre neonatal intensive care unit. Read More

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Technical feasibility of umbilical cannulation in midgestation lambs supported by the EXTra-uterine Environment for Neonatal Development (EXTEND).

Artif Organs 2019 Dec 28;43(12):1154-1161. Epub 2019 Jul 28.

Center for Fetal Research, Department of Surgery, Children's Hospital of Philadelphia Research Institute, Philadelphia, Pennsylvania.

EXTEND (EXTra-uterine Environment for Neonatal Development) is a novel system for supporting extremely premature infants that replicates in utero conditions by maintaining a sterile fluid environment and providing gas exchange via a pumpless arteriovenous oxygenator circuit connected to the umbilical vessels. Target gestational age (GA) for EXTEND support in human infants is 23-27 weeks, when immature lungs are most susceptible to injury in the setting of air ventilation. We previously demonstrated physiologic support of premature lambs cannulated at 105-117 days GA (lungs developmentally analogous to the 23-27 week GA human infant) for up to 28 days on EXTEND. Read More

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December 2019

Relation of shunt index with the patent ductus arteriosus among preterm infants under 30 weeks or 1500 g.

J Matern Fetal Neonatal Med 2019 Mar 25:1-6. Epub 2019 Mar 25.

c Department of Pediatrics, Division of Pediatric Cardiology, Faculty of Medicine , Atatürk University , Erzurum , Turkey.

Objective: Patent ductus arteriosus is an important problem in preterms. We aimed to investigate the relation of patent ductus arteriosus with shunt index.

Methods: The preterm infants with a birth weight of ≤1500 g and/or gestational age of <30 weeks and an indication for umbilical artery and venous catheterization formed the study group. Read More

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Balloon atrial septostomy at the bedside versus the catheterisation laboratory.

Cardiol Young 2019 Mar 28;29(3):454. Epub 2019 Jan 28.

Department of Cardiology,Sree Chitra Tirunal Institute for Medical Sciences and Technology,Thiruvananthapuram,Kerala,India.

A shorter umbilical venous approach provides an opportunity for balloon atrial septostomy in the younger neonate as opposed to those who present at the end of first week of life. However, the ideal choice of access for a bedside balloon atrial septostomy is not well established. Wouldn't prostaglandin infusion be a safer option for transport of babies with dextro-transposition in the neonatal period, when the arterial duct can be kept open? A prenatal diagnosis of dextro-transposition facilitates monitoring and planning of septostomy in the early neonatal period explaining why babies underwent bedside procedures more often. Read More

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Difficult Vascular Access in Urgent Coronary Artery Angiogram: A Rare Case of a Persistent Sciatic Artery.

JACC Cardiovasc Interv 2018 09 15;11(17):e141-e142. Epub 2018 Aug 15.

Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.

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September 2018

Antenatal exposure to nonsteroidal anti-inflammatory drugs and risk of neonatal hypertension.

J Clin Hypertens (Greenwich) 2018 09 27;20(9):1334-1341. Epub 2018 Jul 27.

Perinatal Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, Ohio.

Nonsteroidal anti-inflammatory drugs (NSAIDs) are used as tocolytics, which are medications that suppress uterine contractions for preterm birth prevention. Their effect on cerebral/systemic vascular beds poses the question of whether antenatal NSAID exposure is associated with neonatal hypertension. We performed a retrospective case-control study in a tertiary neonatal intensive care unit, including 40 hypertension cases (hospitalized neonates ≥ 35 weeks with systolic BP > 100 mm Hg on three consecutive days) compared to 134 controls matched by gestational age at delivery, plurality, and delivery date. Read More

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September 2018

Catheter-Related Arterial Thrombosis in Neonates and Children: A Systematic Review.

Thromb Haemost 2018 06 25;118(6):1058-1066. Epub 2018 Apr 25.

Division of Hematology, University Children's Hospital, Zurich, Switzerland.

Catheter-related arterial thrombosis (CAT) is increasingly recognized in children. Available data are scarce and based on expert opinions. This systematic review aimed to identify knowledge on paediatric CAT. Read More

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Failed umbilical artery catheterization and adverse outcomes in extremely low birth weight infants.

J Matern Fetal Neonatal Med 2019 Nov 2;32(21):3566-3570. Epub 2018 May 2.

a Division of Neonatal and Developmental Medicine, Department of Pediatrics , Stanford University School of Medicine , Palo Alto , CA , USA.

To determine whether successful catheterization of the umbilical artery is associated with a reduced risk of death or neurodevelopment impairment among critically ill extremely low birth weight (ELBW) infants. A retrospective chart review was conducted between 2007 and 2014 at Stanford University for all ELBW infants that required intubation immediately after birth. The primary outcome was death or neurodevelopmental impairment at 18-22 months. Read More

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November 2019

Noncanonical Matrix Metalloprotease 1-Protease-Activated Receptor 1 Signaling Drives Progression of Atherosclerosis.

Arterioscler Thromb Vasc Biol 2018 06 5;38(6):1368-1380. Epub 2018 Apr 5.

From the Center for Hemostasis and Thrombosis Research, Tufts Medical Center, Tufts University School of Medicine, Boston, MA (R.R., T.H., G.K., E.K.F., S.E.T., A.S., L.C., A.K.)

Objective: Protease-activated receptor-1 (PAR1) is classically activated by thrombin and is critical in controlling the balance of hemostasis and thrombosis. More recently, it has been shown that noncanonical activation of PAR1 by matrix metalloprotease-1 (MMP1) contributes to arterial thrombosis. However, the role of PAR1 in long-term development of atherosclerosis is unknown, regardless of the protease agonist. Read More

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Postnatal dilatation of umbilical cord vessels and its impact on wall integrity: Prerequisite for the artificial placenta.

Int J Artif Organs 2018 Jul 22;41(7):393-399. Epub 2018 Mar 22.

1 Division of Neonatology, Department of Pediatrics, McMaster University, Hamilton, ON, Canada.

Introduction: A lung assist device, which acts as an artificial placenta, can provide additional gas exchange for preterm and term newborns with respiratory failure. The concept of the lung assist device requires a large bore access via umbilical vessels to allow pumpless extracorporeal blood flow rates up to 30 mL/kg/min. After birth, constricted umbilical vessels need to be reopened for vascular access. Read More

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Role of ultrasound for central catheter tip localization in neonates: a review of the current evidence.

J Matern Fetal Neonatal Med 2019 Jul 15;32(14):2429-2437. Epub 2018 Feb 15.

b Department of Pulmonology , Mofid Children's Hospital, Shahid Beheshti University of Medical Sciences , Tehran , Iran.

Central catheters are known as "life lines" in intensive care units and are used frequently in neonatal intensive care unit (NICU) for multiple indications. The central catheters used in NICU includes umbilical venous catheter (UVC), umbilical arterial catheter (UAC) and peripherally inserted central catheter (PICC) lines. The tip of these central lines needs to be in a correct position as malpositioned central line tips lead to many neonatal complications. Read More

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Umbilical cannulation optimizes circuit flows in premature lambs supported by the EXTra-uterine Environment for Neonatal Development (EXTEND).

J Physiol 2018 05 2;596(9):1575-1585. Epub 2018 Mar 2.

Center for Fetal Research, Department of Surgery.

Key Points: Bronchopulmonary dysplasia is a disease of extreme prematurity that occurs when the immature lung is exposed to gas ventilation. We designed a novel 'artificial womb' system for supporting extreme premature lambs (called EXTEND) that obviates gas ventilation by providing oxygen via a pumpless arteriovenous circuit with the lamb submerged in sterile artificial amniotic fluid. In the present study, we compare different arteriovenous cannulation strategies on EXTEND, including carotid artery/jugular vein (CA/JV), carotid artery/umbilical vein (CA/UV) and umbilical artery/umbilical vein (UA/UV). Read More

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Repair of a mycotic abdominal aortic aneurysm in a neonate using an everted jugular vein patch.

J Vasc Surg Cases Innov Tech 2017 Dec 2;3(4):218-220. Epub 2017 Nov 2.

Section of Pediatric Surgery, Department of Surgery, Yale University School of Medicine, New Haven, Conn.

A 43-day-old boy presented with bacteremia after umbilical artery catheterization. Duplex ultrasound examination revealed a 1.1- × 1. Read More

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December 2017

Umbilical artery perforation: a potentially life-threatening complication of umbilical artery catheterisation.

BMJ Case Rep 2017 Nov 14;2017. Epub 2017 Nov 14.

Department of Neonatology, VU University Medical Center, Amsterdam, The Netherlands.

Umbilical artery catheterisation is frequently performed in preterm or critically ill newborn infants for invasive monitoring of blood pressure and blood sampling for laboratory tests. It is associated with well-known complications like catheter-related infections, thromboembolic events and aneurysmal formation of the aorta. In this report, we present another major complication of umbilical artery catheterisation: umbilical artery perforation. Read More

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November 2017

Association between Umbilical Catheters and Neonatal Outcomes in Extremely Preterm Infants.

Am J Perinatol 2018 Feb 14;35(3):233-241. Epub 2017 Sep 14.

Department of Pediatrics, University of Alberta, Edmonton, Alberta, Canada.

Objective:  The objective of this study was to examine the association between umbilical catheters and a composite outcome of mortality or major neonatal morbidity in extremely preterm infants.

Study Design:  Data were abstracted from the Canadian Neonatal Network database for infants born at <29 weeks' gestational age and admitted to 29 neonatal intensive care units between January 2010 and December 2012. Four groups were identified: those with no umbilical catheters, umbilical venous catheters (UVCs), umbilical artery catheters (UACs), and those with both UVCs and UACs. Read More

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February 2018

Accuracy of 11 formulae to guide umbilical arterial catheter tip placement in newborn infants.

Arch Dis Child Fetal Neonatal Ed 2018 Jul 17;103(4):F364-F369. Epub 2017 Aug 17.

Newborn Research, The Royal Women's Hospital, Melbourne, Australia.

Background: Umbilical arterial catheter (UAC) insertion is a common procedure in the neonatal intensive care unit (NICU). Correct placement of the tip of the UAC at first attempt minimises handling of the infant and reduces the risk of infection and complications. We aimed to determine the accuracy of 11 published formulae to guide UAC placement. Read More

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Vessel Perforation and False Tracking Resulting From Umbilical Artery Catheterization: A Case Report and Literature Review.

Pediatr Dev Pathol 2017 Sep-Oct;20(5):426-431. Epub 2017 Jan 26.

1 Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.

We report an extremely low-birth-weight neonate who developed umbilical artery perforation and false tracking. There was no life-threatening event relating to the complication. Diagnosis was made at postmortem examination. Read More

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A Newborn with an Alternative Porto-Caval Shunt.

Pol J Radiol 2017 16;82:320-321. Epub 2017 Jun 16.

Department of Radiology, Gazi University, Faculty of Medicine, Ankara, Turkey.

Background: Absent ductus venosus (ADV) is a rare condition, but it should be known that this embryonic anomaly may be detected by fetal echocardiographic or newborn ultrasound examinations.

Case Report: We present a baby with an ADV and an accompanying alternative porto-caval shunt between the right portal vein and inferior vena cava detected on postnatal ultrasound examination.

Conclusions: Variations in the fetal umbilical or porto-systemic circulations should be detected by fetal or newborn ultrasound examinations and kept in mind before common interventions such as UV catheterizations. Read More

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