536 results match your criteria Caspian journal of internal medicine[Journal]


Coronavirus disease 2019 (COVID-19): What we need to know.

Caspian J Intern Med 2020 ;11(2):235-236

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

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http://dx.doi.org/10.22088/cjim.11.2.23DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265506PMC
January 2020

A case of thyroxine (T4) toxicosis complicated by thyroid storm with an unusual precipitant.

Caspian J Intern Med 2020 ;11(2):231-234

Endocrinology, Diabetes and Metabolism Division, Department of Internal Medicine, Babcock University Teaching Hospital, Ilishan-Remo, Ogun State, Nigeria.

Background: Thyrotoxicosis, though commonly encountered in endocrinology practice in Nigeria, seldom presents solely as thyroxine (T4) toxicosis. Thyroid storm, a known life-threatening complication of thyrotoxicosis, can be precipitated by myriad factors. Fine need aspiration for cytology is not known, and has not been previously reported (to the best of our knowledge) to precipitate thyroid storm. Read More

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http://dx.doi.org/10.22088/cjim.11.2.231DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265511PMC
January 2020

Combination antifungal therapy without craniotomy in an immunocompromised patient with rhino-orbito-cerebral mucormycosis: A case report.

Caspian J Intern Med 2020 ;11(2):227-230

Imam Khomeini Complex Hospital, Department of Infectious Diseases, Tehran University of Medical Sciences, Tehran, Iran.

Background: Mucormycosis is an uncommon fungal infection caused by the members of the order Mucorales. In susceptible patients, mucormycosis can infect any tissue or organ, and without suitable treatment (i.e. Read More

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http://dx.doi.org/10.22088/cjim.11.2.227DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265517PMC
January 2020

Concurrence of multiple sclerosis and primary biliary cholangitis: Report of 3 cases.

Caspian J Intern Med 2020 ;11(2):223-226

Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system which damages the myelin and axon. Primary biliary cholangitis (PBC) is a slow progressive liver disease with autoimmune feature in which non-purulent destructive cholangitis and interlobular bile duct destruction occur. Involvement of each of PBC and MS is thought to be related to environmental exposure in genetically susceptible persons. Read More

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http://dx.doi.org/10.22088/cjim.11.2.223DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265518PMC
January 2020

Investigating the relationship of positive family history pattern and the incidence and prognosis of idiopathic epilepsy in epilepsy patients.

Caspian J Intern Med 2020 ;11(2):219-222

Department of Neurology, Faculty of Medicine, Hamadan University of Medical Sciences , Hamadan, Iran.

Background: Epilepsy is one of the most common neurological disorder. This study aimed to investigating the relationship of family history pattern and prognosis of idiopathic epilepsy.

Methods: In this study, 377 patients with epilepsy referring to Imam clinic were investigated. Read More

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http://dx.doi.org/10.22088/cjim.11.2.219DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265512PMC
January 2020

Prevalence and factors related to psychiatric symptoms in low risk pregnancy.

Caspian J Intern Med 2020 ;11(2):211-218

Infertility and Health Reproductive Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Psychiatric disorders are associated with poor pregnancy outcomes both for mother and child. This study aimed to determine the prevalence and related demographic risk factors of psychiatric symptoms among the pregnant women in Babol City.

Methods: This cross-sectional study was conducted in five private and public obstetrics clinics of Babol city. Read More

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http://dx.doi.org/10.22088/cjim.11.2.211DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265507PMC
January 2020

HBS Ag seroclearance and seroconversion time in Patients with chronic hepatitis B Infection.

Caspian J Intern Med 2020 ;11(2):205-210

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Hepatitis B Surface antigen (HBsAg) seroclearance and seroconversion (development of antibodies against HBsAg) can increases the survival of Chronic hepatitis B (CHB) patients. The aim of this study was to determine the percentage and timing of HBsAg seroclearance and seroconversion in patients with chronic hepatitis B infection.

Methods: 1026 patients with CHB infection who referred to a private clinic were included. Read More

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http://dx.doi.org/10.22088/cjim.11.2.205DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265509PMC
January 2020

Prevalence of torque teno virus in healthy individuals and those infected with hepatitis C virus living in Yazd, Iran.

Caspian J Intern Med 2020 ;11(2):199-204

Gastroentrology Department, Shahid Sadoughi Hospital, Faculty of Medicine,, Shahid Sadoughi University of Medical Sciences,Yazd, Iran.

Background: Torque teno virus (TTV) is a non-enveloped DNA virus that its role as a helper or causative agent in hepatitis is still unclear. TTV prevalence varies in different regions of the world. This study aimed to determine the prevalence of TTV in healthy individuals and those infected with hepatitis C virus (HCV) living in Yazd city, Iran. Read More

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http://dx.doi.org/10.22088/cjim.11.2.199DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265513PMC
January 2020

Applying GC-MS analysis to identify chemical composition of Iranian propolis prepared with different solvent and evaluation of its biological activity.

Caspian J Intern Med 2020 ;11(2):191-198

Oral Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Propolis as a natural product has shown beneficial effects on human health. This study was aimed to investigate the chemical compositions and biological activity of three different extracts of propolis from two distinct geographic areas in Iran.

Methods: The chemical composition of Iranian propolis extracts that were collected in the Spring of 2016 from two provinces in northern Iran: Ardabil and Polur in Mazandaran Province were measured through gas chromatography-mass spectrometry (GC-MS) methods. Read More

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http://dx.doi.org/10.22088/cjim.11.2.191DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265523PMC
January 2020

Anthropometric measures and the risk of coronary artery disease.

Caspian J Intern Med 2020 ;11(2):183-190

Department of Internal Medicine, School of Medicine, AJA University of Medical Sciences, Tehran, Iran.

Background: Nowadays, obesity and overweight are projected to become main risk factors for coronary artery disease (CAD). We aimed to determine the association of anthropometric measures with presence of significant (sig.) CAD as evaluated by coronary angiography, among an adult Iranian population. Read More

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http://dx.doi.org/10.22088/cjim.11.2.183DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265515PMC
January 2020

Albumin excretion rate among patients with diabetic retinopathy.

Caspian J Intern Med 2020 ;11(2):177-182

Department of Biostatistics, Faculty of Public Health, University of Hasanuddin, Makassar, Indonesia.

Background: Chronic microvascular complications consist of diabetic nephropathy (DN), diabetic retinopathy (DR), and diabetic neuropathy. Diabetic nephropathy is assessed through albuminuria, and diabetic retinopathy is assessed through fundoscopy. Several studies have assessed the albuminuria in diabetic retinopathy but have found inconclusive results. Read More

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http://dx.doi.org/10.22088/cjim.11.2.177DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265519PMC
January 2020

Phenotypic and genotypic detection of metallo-beta-lactamases in Carbapenem resistant Acinetobacter baumannii.

Caspian J Intern Med 2020 ;11(2):171-176

Infectious Diseases and Tropical Medicine Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Carbapenem resistance in has become a major concern for treating physicians. The aim of this study was to investigate the prevalence of metallo β-lactamase (MBL) genes () among isolated multidrug-resistant .

Methods: Fifty non-repetitive carbapenem-resistant isolates were collected. Read More

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http://dx.doi.org/10.22088/cjim.11.2.171DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265521PMC
January 2020

Comparison of two manual therapy techniques in patients with carpal tunnel syndrome: A randomized clinical trial.

Caspian J Intern Med 2020 ;11(2):163-170

Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Manual therapy techniques are part of physiotherapy treatment of carpal tunnel syndrome (CTS) which are classified into two groups including nerve mobilization and mechanical interface mobilization. The aim of the study was to find which manual therapy method-technique directed to mechanical interface and nerve mobilization-has superior beneficial effects on clinical and electrophysiological findings in conservative management of patients with CTS.

Methods: Thirty patients with CTS participated into two groups namely: mechanical interface and nerve mobilization in this randomized clinical trial. Read More

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http://dx.doi.org/10.22088/cjim.11.2.163DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265508PMC
January 2020

Efficacy and safety of rituximab in patients with refractory neuromyelitis optica spectrum disorders: A prospective observation in Iranian cases.

Caspian J Intern Med 2020 ;11(2):155-162

Multiple Sclerosis Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran.

Background: Rituximab has been used successfully in the recent years for treatment of neuromyelitis optica spectrum disorders (NMOSD). However, a uniform treatment protocol for maintenance therapy and the best interval for evaluation and retreatment have not been postulated. We evaluated the efficacy and safety of rituximab treatment as second line therapy, in Iranian patients with refractory NMOSD, based on annualized relapse rate (ARR) and expanded disability status scale (EDSS). Read More

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http://dx.doi.org/10.22088/cjim.11.2.155DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265520PMC
January 2020

Comparison of CD4+ and CD8+ T- lymphocyte in Helicobacter pylori-negative functional dyspepsia.

Caspian J Intern Med 2020 ;11(2):150-154

Liver and Gastrointestinal Diseases Research Center, Imam Reza Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.

Background: Functional dyspepsia (FD) is the most common gastrointestinal disorder with several symptoms such as stomach pain and abdominal bloating. The aim of this study was to investigate and compare CD4+ and CD8+ in the Helicobacter pylori-negative functional dyspepsia and control groups.

Methods: Sixty one patients (35 patients with stomach pain and 26 with abdominal bloating), and 30 controls were reviewed based on the quantity of CD4+ and CD8+ T-cells isolated from gastric mucosa biopsy samples. Read More

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http://dx.doi.org/10.22088/cjim.11.2.150DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265516PMC
January 2020

Helicobacter pylori eradication in the management of glaucoma.

Caspian J Intern Med 2020 ;11(2):143-149

Pharmaceutical Research Center, Faculty of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.

Background: To investigate the possibility that the eradication of infection is associated with a reduction in the risk of glaucoma.

Methods: Sixty-five successive patients with elevated intraocular pressure (IOP) or glaucoma were included in the study. Serum samples from all subjects were analyzed for the presence of - antibodies using ELISA. Read More

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http://dx.doi.org/10.22088/cjim.11.2.143DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265522PMC
January 2020

Systemic effects of starved fibroblast culture supernatant on immunosuppressed rats treated with cancer stem cells (LA7).

Caspian J Intern Med 2020 ;11(2):135-142

Cellular and Molecular Biology Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: The present study aimed to investigate and compare the effect of starved fibroblast culture supernatant (SFS), DMEM and normal saline alone or along with LA7 on dexamethasone-treated immunosuppressed Wistar rats.

Methods: After the isolation of fibroblasts from the fresh foreskin of children, it was cultured in serum-free DMEM, and the supernatant collected after 16 hours (16h-SFS). This solution and the other treatments were injected subcutaneously into the rats from each group once daily for 14 days. Read More

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http://dx.doi.org/10.22088/cjim.11.2.135DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265514PMC
January 2020

Prevalence rate of laboratory defined aspirin resistance in cardiovascular disease patients: A systematic review and meta-analysis.

Caspian J Intern Med 2020 ;11(2):124-134

Department of Health Services Management, School of Health Management and Information Sciences, Iran University of Medical Sciences, Tehran, Iran.

Background: Cardiovascular disease (CVD) is the first cause of mortality worldwide, with all the healthcare systems facing this very challenging issue. Aspirin continues to be the major gold-standard treatment worldwide in the prevention of thrombotic disease in patients with CVD, even though not all individuals respond to antiplatelet therapy in a similar way, being resistant to aspirin. The aim of this study was to determine the prevalence of laboratory defined aspirin resistance in CVD patients worldwide. Read More

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http://dx.doi.org/10.22088/cjim.11.2.124DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265510PMC
January 2020

Challenging case of muscle bridge; a 15-year follow-up of a patient.

Caspian J Intern Med 2020 ;11(1):120-123

School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.

Background: Anatomically myocardial bridging (MB) consists of either superficial myocardial fibers that traverse over the LAD or deep fibers that encircle the coronary artery. In this study, we present a patient with myocardial bridging, who was primarily diagnosed with coronary artery disease which did not properly respond to full-dose medical treatment but benefited from coronary artery bypass graft (CABG).

Case Presentation: In 2017, a 53-year old man was referred to Tehran Heart Center (THC) with complaint of typical chest pain (TCP). Read More

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http://dx.doi.org/10.22088/cjim.11.1.120DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992718PMC
January 2020

A case of aberrant bilateral vertebral arteries orgin presenting with right VA dissection.

Caspian J Intern Med 2020 ;11(1):116-119

Department of Neurology, Firoozgar Hospital, Iran University of Medical Sciences, Tehran, Iran.

Background: Knowledge of variations in the origin of vertebral artery (VA) is indispensable to vascular surgeons. Aberrant origin of vertebral artery on either side is an uncommon finding. There are unilateral and bilateral variability in VA origin. Read More

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http://dx.doi.org/10.22088/cjim.11.1.116DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992730PMC
January 2020

Papillary carcinoma in correlation to thyroidal duct cyst: A case series.

Caspian J Intern Med 2020 ;11(1):110-115

Department of Internal Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Persistent thyroglossal duct leads to a fibrous cyst formation named thyroglossal cyst which is the most common form of congenital cyst and usually located in the midline neck below the hyoid bone. Rarely the thyroglossal cyst is associated with thyroid cancer. Although the Sistrunk procedure is often considered adequate, currently there is no clear consensus on the optimal management of thyroglossal duct cyst especially duct cyst carcinoma. Read More

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http://dx.doi.org/10.22088/cjim.11.1.110DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992716PMC
January 2020

Bernard-Soulier syndrome or idiopathic thrombocytopenic purpura: A case series.

Authors:
Nahid Reisi

Caspian J Intern Med 2020 ;11(1):105-109

Department of Pediatric Hematology and Oncology, Faculty of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran.

Background: Bernard-Soulier syndrome (BSS) is a rare, autosomal recessive platelet function disorder which is commonly mistaken for idiopathic thrombocytopenic purpura (ITP).The report includes seven cases of BSS that have been diagnosed and treated as ITP for a long time.

Methods: Between 2006 and 2016, data of seven BSS patients who have long been diagnosed and treated as ITP were collected and analyzed. Read More

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http://dx.doi.org/10.22088/cjim.11.1.105DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992729PMC
January 2020

Rate of urinary tract infection after urodynamic study in pelvic floor clinic.

Caspian J Intern Med 2020 ;11(1):100-104

Department of Uro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.

Background: One of the complications of urodynamic study is urinary tract infection. The aim of this study was to determine the rate of urinary tract infection (UTI) after UDS in patients referred to the pelvic floor clinic with regard to the specific conditions of these patients, such as presence of pelvic organ prolapse and high post voiding residual volume (PVR).

Methods: In a prospective descriptive-analytic study, 146 female candidates for UDS from January 2016 to June 2017 entered the study. Read More

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http://dx.doi.org/10.22088/cjim.11.1.100DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992731PMC
January 2020

Effect of hydroalcoholic extract of flaxseed on bone mineral density in Wistar rats using digital radiography.

Caspian J Intern Med 2020 ;11(1):92-99

Oral Health Researche Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Given that the world's population is aging, the problems associated with osteoporosis and related fractures are increasing. The aim of the study was to evaluate the effect of flaxseed extract on bone mineral density (BMD) in Wistar rats using digital radiography.

Methods: In this experimental study, 25 male and 25 female Wistar rats were randomly divided into 5 groups: 1. Read More

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http://dx.doi.org/10.22088/cjim.11.1.92DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992728PMC
January 2020

Association of serum magnesium levels with risk factors, severity and prognosis in ischemic and hemorrhagic stroke patients.

Caspian J Intern Med 2020 ;11(1):83-91

School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.

Background: Stroke is the third leading cause of mortality worldwide. One of the factors that affect the occurrence of stroke can be attributed to changes in the levels of trace elements. Accumulating evidence has been shown that magnesium, as an important element, is a new predictor of stroke. Read More

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http://dx.doi.org/10.22088/cjim.11.1.83DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992732PMC
January 2020

Prevalence of K-RAS mutations and CA125 tumor marker in patients with ovarian carcinoma.

Caspian J Intern Med 2020 ;11(1):75-82

Biotechnology Research Center, Tabriz University of Medical Science, Tabriz, Iran.

Background: Ovarian carcinoma is one of the leading causes of cancer-related death among females. K-ras codon 12 mutations are commonly occurring mutations in different types of cancers and leads to resistance against anti-EGFR therapeutics. Hence, determination of mutations in k-ras gene is crucial for predicting response to anti-EGFR therapies. Read More

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http://dx.doi.org/10.22088/cjim.11.1.75DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992719PMC
January 2020

Total delay and associated factors in pulmonary tuberculosis patients in Golestan province.

Caspian J Intern Med 2020 ;11(1):67-74

Department of Biostatistics, Faculty of Health, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Delay in diagnosis and treatment of TB is a critical component in TB control program which thereby spreading illness in the community. Sicnce Golestan province has the high risk with high rates of tuberculosis in the country, therefore, the analysis of the factors associated with treatment delay in this province for effective interventions and proper planning is considered necessary.

Methods: 689 patients documents of TB cases in the health department of Golestan University of Medical Sciences in 2016 were enrolled in this survey. Read More

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http://dx.doi.org/10.22088/cjim.11.1.67DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992724PMC
January 2020

The effect of aqueous and ethanolic extract of Iranian propolis on Candida Albicans isolated from the mouth of patients with colorectal malignancy undergone chemotherapy: An in-vitro study.

Caspian J Intern Med 2020 ;11(1):62-66

Oral Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Candidiasis is one of the most common fungal infections in immunosuppressed patients. The condition is usually treated with local and systemic antifungal agents. Given the antifungal properties of propolis, it appears this natural resin material can be effective in treating this infection. Read More

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http://dx.doi.org/10.22088/cjim.11.1.62DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992721PMC
January 2020

Triglyceride to high-density lipoprotein cholesterol and low-density lipoprotein cholestrol to high-density lipoprotein cholesterol ratios are predictors of cardiovascular risk in Iranian adults: Evidence from a population-based cross-sectional study.

Caspian J Intern Med 2020 ;11(1):53-61

Department of Midwifery, Babol University of Medical Sciences, Babol, Iran.

Background: The superiority of TG/HDL-C and LDL-C/HDL-C ratios in predicting CVD risk is a matter of debates. Thus, the objective of this study was to compare TG/HDL-C and LDL-C to HDL-C ratios in predicting the risk of CVD events.

Methods: In a population-based cross-sectional study, 567 representative participants aged 40 years or older were entered in the study in Babol, North of Iran. Read More

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http://dx.doi.org/10.22088/cjim.11.1.53DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992727PMC
January 2020

Smoking status and changes in thyroid-stimulating hormone and free thyroxine levels during a decade of follow-up: The Tehran thyroid study.

Caspian J Intern Med 2020 ;11(1):47-52

Prevention of Metabolic Disorders Research Center Research Institute for Endocrine Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Smoking can cause thyroid disorders; the aim of the present study was to investigate the association between smoking status and changes in thyroid hormone levels among adult males during a decade long follow-up of in the Tehran Thyroid Study (TTS).

Methods: Data of 895 adult males (smokers=115, non-smokers=691, ex-smokers=89) participants of the TTS without any previously known thyroid disease were analyzed. To examine trends of changes in thyroid hormone levels in these three groups, generalized estimating equation models were used. Read More

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http://dx.doi.org/10.22088/cjim.11.1.47DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992726PMC
January 2020

Real-life efficacy of generic sofosbuvir/ledipasvir for treatment of Iranian patients with chronic hepatitis C: A cohort study.

Caspian J Intern Med 2020 ;11(1):41-46

Baqiyatallah Research Center for Gastroenterology and Liver Diseases, Baqiyatallah University of Medical Sciences, Tehran, Iran.

Background: Treatment of hepatitis C virus (HCV) infection with recently introduced direct-acting antiviral agents (DAA) is effective and safe, however there is little known regarding safety and efficacy of generic DAAs in the real-life clinical setting. This study aimed to evaluate the efficacy and safety of generic sofosbuvir/ledipasvir (SOF/LDV) in a real-life clinical experience.

Methods: In this prospective cohort study, patients with chronic HCV infection who referred to Middle East Liver Diseases (MELD) Center were included. Read More

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http://dx.doi.org/10.22088/cjim.11.1.41DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992720PMC
January 2020

Comparing the effect of kangaroo mother care and field massage on serum bilirubin level of term neonates with hyperbilirubinemia under phototherapy in the neonatal ward.

Caspian J Intern Med 2020 ;11(1):34-40

Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Several factors contribute to the effectiveness of phototherapy. The aim of this study was to compare the effect of kangaroo mother care (KMC) and field massage on bilirubin level of term neonates with hyperbilirubinemia under phototherapy in the neonatal ward.

Methods: This double-blind clinical trial was performed on 90 term neonates aged 48 hours with hyperbilirubinemia, hospitalized in Fereydunkenar Hospital during 2018-2019. Read More

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http://dx.doi.org/10.22088/cjim.11.1.34DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992723PMC
January 2020

Comparison of the calcium-related factors in Parkinson's disease patients with healthy individuals.

Caspian J Intern Med 2020 ;11(1):28-33

Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Parkinson's disease (PD) is one of the most common neurodegenerative diseases (ND). Studies have demonstrated that biochemical markers have an association with PD. We aimed to investigate an association of biochemical markers including calcium, vitamin D, alkaline phosphatase (ALP), parathormone (PTH), and phosphorous with PD. Read More

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http://dx.doi.org/10.22088/cjim.11.1.28DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992725PMC
January 2020

Assessment of left ventricular torsion in long axis view in patients with chronic stenosis of coronary arteries.

Caspian J Intern Med 2020 ;11(1):21-27

Metabolic Disorders Research Center, Golestan University of Medical Sciences, Gorgan, Iran.

Background: Left ventricular torsion is one of the most important biomechanical parameters of heart that routinely is measured in short axis view. A review of the literature has indicated that assessment of left ventricular torsion in short axis view has some limitations. In the present study, we evaluated whether torsion angle assessment in long axis view can be used as a diagnostic biomechanical marker in patients with coronary artery disease (CAD). Read More

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http://dx.doi.org/10.22088/cjim.11.1.21DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992717PMC
January 2020

Evaluating the effect of a herb on the control of blood glucose and insulin-resistance in patients with advanced type 2 diabetes (a double-blind clinical trial).

Caspian J Intern Med 2020 ;11(1):12-20

Gastroenterology & Hepatology Disease Research Center, Qom University of Medical Science, Qom, Iran.

Background: Different benefits of various herbal medicines in decreasing blood sugar have been reported in different clinical trials so far. Considering the growing tendency toward these combinations and the booming market, inappropriate advice is growing accordingly. Hence, it is necessary to evaluate the effects and possible complications of such combinations on health status and blood glucose control. Read More

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http://dx.doi.org/10.22088/cjim.11.1.12DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992722PMC
January 2020

A systematic review and meta-analysis on the association of serum and tumor tissue iron and risk of breast cancer.

Caspian J Intern Med 2020 ;11(1):1-11

Faculty of Medicine, Ilam University of Medical Sciences, Ilam, Iran.

Background: Some studies have investigated the effects of iron on breast carcinogenesis and reported different findings about the association between Fe and breast cancer risk. This study was conducted to estimate this effect using meta-analysis method.

Methods: A total of 20 articles published between 1984 and 2017 worldwide were selected through searching PubMed, Scopus, Embase, Web of Science, and Cochrane Library. Read More

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http://dx.doi.org/10.22088/cjim.11.1.1DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6992715PMC
January 2020

Parvimonas micra bacteremia in a patient with colonic carcinoma.

Caspian J Intern Med 2019 ;10(4):472-475

Department of Internal Medicine, Marshfield Clinic Health System, Marshfield, Wisconsin, USA.

Background: is a gram-positive anaerobe and a part of the normal commensal flora of the gastrointestinal tract. Factors predisposing to anaerobic bacteremia include malignant neoplasms, periodontal disease, immune deficiencies, chronic renal insufficiency, decubitus ulcers and perforated abdominal viscus. Cases of Parvimonas bacteremia in a patient with esophageal carcinoma and in a patient following ERCP procedure have been reported but to our best knowledge no case has been reported yet in which a patient had colonic carcinoma. Read More

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http://dx.doi.org/10.22088/cjim.10.4.472DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856917PMC
January 2019

Benign schwannoma of posterior mediastinum accompanied by bloody pleural effusion misdiagnosed as solitary fibrous tumor: A case report.

Caspian J Intern Med 2019 ;10(4):468-471

Department of Pathology, Ayatollah Rouhani Hospital, Babol University of Medical Sciences, Babol, Iran.

Background: Schwannoma is a peripheral nerve sheath tumor originating from schwann cells. It is the most common neurogenic tumor of the posterior mediastinum. Pleural effusion is a rare presentation of benign schwannoma and it is mainly related to malignant tumors. Read More

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http://dx.doi.org/10.22088/cjim.10.4.468DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856921PMC
January 2019

Bradycardia caused by interaction of venlafaxine and cyclosporine: A case report.

Caspian J Intern Med 2019 ;10(4):463-467

Department of Internal Medicine, Orthopedic Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

Background: Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are prescribed widely for the treatment of depression, anxiety disorders and other psychiatric disorders. Although antidepressants are considered as a safety drug category but unexpected cardiovascular events have been reported as the most serious complications. The aim of this study was to introduce a case presentation on bradycardia due to the drug interference of venlafaxine and cyclosporine. Read More

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http://dx.doi.org/10.22088/cjim.10.4.463DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856918PMC
January 2019

Butyrylcholinesterase level in poisoned patients with phosphide compounds.

Caspian J Intern Med 2019 ;10(4):458-462

Department of Community Medicine, School of Medicine, Hamadan University of Medical Sciences, Hamadan, Iran.

Background: Metal phosphides are widely used as a rodenticide and insecticide and poisoning with these substances has a very high mortality. The aim of this study was to evaluate the butyrylcholinesterase (BuCh) level in poisoning with metal phosphides.

Methods: In this case series study, 60 poisoned patients with zinc phosphide (ZnP) and aluminum phosphide (ALP) who was admitted to poisoning ward in Hamadan, Iran, enrolled in the study and BuCh level was measured. Read More

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http://dx.doi.org/10.22088/cjim.10.4.458DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856910PMC
January 2019

Effect of (Carob) syrup and vitamin E on sperm parameters, oxidative stress index and sex hormones in infertile men: Protocol for a randomized controlled trial.

Caspian J Intern Med 2019 ;10(4):452-457

Pharmaceutical Sciences Research Center and School of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran, Iran.

Background: Spermatogenesis is a necessary process in fertility and reproductive capacity of humans. In view of the relative high prevalence of spermatogenesis disorders in men and the failure of treatments provided in conventional medicine, new therapeutic approaches are being considered. This study will be designed to investigate the effect of Ceratonia siliqua (Carob) syrup and vitamin E on sperm parameters, oxidative stress index and reproductive hormones in infertile men. Read More

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http://dx.doi.org/10.22088/cjim.10.4.452DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856924PMC
January 2019

Hearing status in patients with rheumatoid arthritis.

Caspian J Intern Med 2019 ;10(4):447-451

Department of Audiology, School of Rehabilitation, Iran University of Medical Sciences, Tehran, Iran.

Background: Previous studies showed that one of the complications of rheumatoid arthritis disease was auditory disorder. The goal of the present study was to compare the auditory status in patients with rheumatoid arthritis and healthy individuals.

Methods: In the present case-control study, 30 normal persons and 60 persons with rheumatoid arthritis with mean age of 46. Read More

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http://dx.doi.org/10.22088/cjim.10.4.447DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856920PMC
January 2019

Anticancer properties of chitosan against osteosarcoma, breast cancer and cervical cancer cell lines.

Caspian J Intern Med 2019 ;10(4):439-446

Dental Materials Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Cancer is still the most common cause of morbidity in the world. Chitosan, a commonly used natural polymer, is consisted of different molecular weight with different biological activities.The purpose of this study was to determine cytotoxicity effect of high molecular weight (HMWC) and low molecular weight of chitosan (LMWC) on three cancerous cell lines MCF-7, HeLa and Saos-2 with different histological origin. Read More

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http://dx.doi.org/10.22088/cjim.10.4.439DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856915PMC
January 2019

Effectiveness of continuous versus pulsed short-wave diathermy in the management of knee osteoarthritis: A randomized pilot study.

Caspian J Intern Med 2019 ;10(4):431-438

University Faculty of Medicine, Department of Physical and Rehabilitation Medicine, Ankara, Turkey.

Background: Short-wave diathermy (SWD) is an electrotherapeutic modality used in the conservative treatment of knee osteoarthritis (KOA). Electromagnetic radiation delivered in continuous (cSWD) or pulse (pSWD) mode provides a deep heating effect on tissues. There is no consensus on outcomes of treatment with cSWD versus pSWD in KOA. Read More

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http://dx.doi.org/10.22088/cjim.10.4.431DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856911PMC
January 2019

Factors predicting the outcome of intravenous thrombolysis in stroke patients before rt-PA administration.

Caspian J Intern Med 2019 ;10(4):424-430

Department of Neurology, Firoozgar Hospital, Iran University of Medical Sciences, (IUMS), Tehran, Iran.

Background: To determine whether it is possible to predict intravenous thrombolytic therapy (IVT) outcome after 3 months in acute ischemic stroke patients who are candidate to receive recombinant tissue plasminogen activator (rt-PA), before rt-PA administration based on their risk factors and some available laboratory results.

Methods: We enrolled 118 ischemic stroke patients who were treated with standard dose of Alteplase in our hospital. Baseline characteristics, door-to-needle time (DTN), onset-to-treatment time (OTT), the National Institute Health Stroke Scale (NIHSS), systolic and diastolic blood pressure on admission, history of diabetes, hypertension, dyslipidemia, coronary artery disease (CAD), previous ischemic stroke, atrial fibrillation (AF), laboratory results were retrospectively collected. Read More

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http://dx.doi.org/10.22088/cjim.10.4.424DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856912PMC
January 2019

Comparison of bladder ultrasonographic and rigid cystoscopic findings in patients with hematuria.

Caspian J Intern Med 2019 ;10(4):417-423

Cancer Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Bladder cancer ranks ninth in world-wide cancer incidence and is 2.5-4 times more common in men, and painless gross hematuria is its typical clinical symptom. Cystoscopy is used to evaluate the cause of hematuria in bladder while the use and reliability of ultrasonography is questionable for this purpose. Read More

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http://dx.doi.org/10.22088/cjim.10.4.417DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856913PMC
January 2019

Overexpression of cancer stem cell marker Lgr5 in colorectal cancer patients and association with clinicopathological findings.

Caspian J Intern Med 2019 ;10(4):412-416

Gastrointestinal Cancer Research Center, Mazandaran University of Medical Science, Sari, Iran.

Background: To determine the expression of cancer stem cell marker Leucine-rich repeat-containing G-protein coupled receptor 5 (Lgr5) in colorectal carcinoma samples compared to normal adjacent tissue and any possible association with clinicopathological findings.

Methods: This study was performed on forty samples of cancerous colorectal tissues (case group) and their adjacent normal mucosa (control group) in Imam Khomeini Hospital (Sari, Mazandaran, Iran). Expression of Lgr5 in tissue sections was done by immunohistochemistry. Read More

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http://dx.doi.org/10.22088/cjim.10.4.411DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856925PMC
January 2019

A cross-sectional study on serum high-sensitivity C-reactive protein level and shift work among reproductive age women.

Caspian J Intern Med 2019 ;10(4):402-410

Mobility Impairment Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Among the inflammatory factors, high-sensitivity C-reactive protein (hs-CRP) is one of the strongest predictors of cardiovascular disease. This study aimed to evaluate the relationship of serum hs-CRP level with shift work among reproductive age women.

Methods: This cross-sectional study was conducted from September 2017 to May 2018 in three cities in Mazandaran Province, North of Iran. Read More

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http://dx.doi.org/10.22088/cjim.10.4.402DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856923PMC
January 2019

A 25-year trend in gastrointestinal cancers in northern Iran (1991-2016).

Caspian J Intern Med 2019 ;10(4):396-401

Social Determinants of Health Research Center, Health Research Institute, Babol University of Medical Sciences, Babol, Iran.

Background: Identifying the incidence of cancer helps in planning and prioritizing resources for its screening, prevention, treatment and diagnosis. This study aimed at investigating a 25-year trend in gastrointestinal cancer in northern Iran during 1991-2016.

Methods: This research was a trend analysis. Read More

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http://dx.doi.org/10.22088/cjim.10.4.396DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856909PMC
January 2019

Association between high sensitivity C-reactive protein (hs-CRP) levels and the risk of major adverse cardiovascular events (MACE) and/or microembolic signals after carotid angioplasty and stenting.

Caspian J Intern Med 2019 ;10(4):388-395

Clinical Neurology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.

Background: To evaluate the association between pre/post-procedural high sensitive C-reactive protein (hs-CRP) level and hs-CRP difference, and the risk of major adverse cardiovascular events (MACE) or new diffusion-weighted MRI lesions after carotid angioplasty and stenting (CAS).

Methods: In this study, conducted in 2016 in Shiraz (Iran), patients who underwent diagnostic angiography and CAS were recruited. CAS was performed with distal embolic protection device on patients with both standard and high risk of endarterectomy. Read More

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http://dx.doi.org/10.22088/cjim.10.4.388DOI Listing
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6856919PMC
January 2019